Diagnsose Sentence Context
Table 1. Analysis of context sentence of 8542 absracts clustered as diagnosis.
| PMID | Gene Context Sentence | ePubDate |
|---|---|---|
| 31944312 | Conventional diagnostic tests, such as the assays for rapid detection of antiviral antibodies or viral antigens, are widely used in many clinical laboratories. […] With the development of modern technologies, new diagnostic strategies, including multiplex nucleic acid amplification and microarray-based assays, are emerging. […] This review summarizes currently available and novel emerging diagnostic methods for the detection of common respiratory viruses, such as influenza virus, human respiratory syncytial virus, coronavirus, human adenovirus, and human rhinovirus. […] It is anticipated that such data will assist researchers and clinicians to develop appropriate diagnostic strategies for timely and effective detection of respiratory virus infections. | 2020-03-19 |
| 31967265 | This case of severe YF with non-fatal outcome emphasizes the importance of adequate syndromic diagnosis, and early and aggressive supportive treatment that can save a patient’s life. | 2020-01-23 |
| 31987001 | These findings provide the basis for starting further studies on the pathogenesis, and optimizing the design of diagnostic, antiviral and vaccination strategies for this emerging infection. | 2020-03-16 |
| 31992387 | We aimed to develop and deploy robust diagnostic methodology for use in public health laboratory settings without having virus material available. […] Here we present a validated diagnostic workflow for 2019-nCoV, its design relying on close genetic relatedness of 2019-nCoV with SARS coronavirus, making use of synthetic nucleic acid technology. | 2020-02-19 |
| 32004427 | We report the first case of 2019-nCoV infection confirmed in the United States and describe the identification, diagnosis, clinical course, and management of the case, including the patient’s initial mild symptoms at presentation with progression to pneumonia on day 9 of illness. | 2020-03-16 |
| 32017984 | Here, we focus on advances in research and development of fast diagnosis methods, as well as potential prophylactics and therapeutics to prevent or treat 2019-nCoV infection. | 2020-03-18 |
| 32020915 | Herein, we present on an overview of the currently available information on the pathogenesis, epidemiology, clinical presentation, diagnosis, and treatment of this virus. | 2020-04-13 |
| 32023681 | To standardize the diagnosis and treatment of this new infectious disease, operational guidelines for the diagnosis and management of 2019-nCoV infection is accomplished by Peking Union Medical College Hospital. | 2020-02-05 |
| 32023682 | After the outbreak of this disease, Chinese scientists invested a lot of energy to carry out research by developing rapid diagnostic reagents, identifying the characters of the pathogen, screening out clinical drugs that may inhibit the virus, and are rapidly developing vaccines. | 2020-02-05 |
| 32023684 | Based on current studies, the author summarized the clinical characteristics and evolution of the novel viral pneumonia, and proposed the key points of diagnosis and treatment, the scientific management of both confirmed and suspected cases, and the scientific management of disease prevention and control. | 2020-02-05 |
| 32023686 | The novel coronavirus has the characteristics of rapid transmission, atypical clinical symptoms, and easy to affect both lungs, leading to missed diagnosis and misdiagnosis, as well as difficult to detection and assessment at early stage. | 2020-02-05 |
| 32026148 | Following the latest National recommendations for diagnosis and treatment of pneumonia caused by 2019-nCoV (the 4th edition) and current status of clinical practice in Zhejiang Province, recommendations for the diagnosis and treatment of respiratory infection caused by 2019-nCoV for children were drafted by the National Clinical Research Center for Child Health, the National Children’s Regional Medical Center, Children’s Hospital, Zhejiang University School of Medicine to further standardize the protocol for diagnosis and treatment of respiratory infection in children caused by 2019-nCoV. | 2020-02-06 |
| 32026671 | According to the relevant diagnostic criteria, the patients were divided into three groups: mild (15 cases), severe (9 cases) and critical (5 cases). […] High resolution CT is of great value in the differential diagnosis of this disease. | 2020-02-06 |
| 32029004 | This guideline includes the guideline methodology, epidemiological characteristics, disease screening and population prevention, diagnosis, treatment and control (including traditional Chinese Medicine), nosocomial infection prevention and control, and disease nursing of the 2019-nCoV. | 2020-03-19 |
| 32033513 | the National Health Commission of the People’s Republic of China publish the guidelines for the diagnosis and treatment of novel coronavirus (2019-nCoV) infection (trial version 5) . | 2020-02-08 |
| 32033514 | It needs to emphasize that bronchoscopy should not be used as a routine means for the diagnosis of 2019-nCoV infection sampling. | 2020-02-08 |
| 32034659 | This statement is based on the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (the fourth edition) (National Health Committee) and other previous diagnosis and treatment strategies for pediatric virus infections. […] The present consensus statement summarizes current strategies on diagnosis, treatment, and prevention of 2019-nCoV infection in children. | 2020-02-08 |
| 32035431 | In about 20 days since the diagnosis of the first case of the 2019 novel coronavirus (2019-nCoV) in Korea on January 20, 2020, 28 cases have been confirmed. | 2020-03-18 |
| 32046815 | Thirty-eight laboratories in 24 EU/EEA countries had diagnostic tests available by 29 January 2020. | 2020-03-20 |
| 32047895 | Saliva is a promising non-invasive specimen for diagnosis, monitoring, and infection control in patients with 2019-nCoV infection. | 2020-04-03 |
| 32048163 | Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection. | 2020-03-19 |
| 32051072 | During the epidemic of 2019-nCoV, the emergency response plan for the NICU should be based on the actual situation, including diagnosis, isolation, and treatment, as well as available equipment and staffing, and take into account the psychosocial needs of the families and neonatal care staff. | 2020-02-19 |
| 32051073 | In order to further standardize and enhance the clinical management of 2019-nCoV infection in children, reduce the incidence, and decrease the number of severe cases, we have formulated this diagnosis and treatment recommendation according to the recent information at home and abroad. | 2020-02-19 |
| 32051074 | Under the unified arrangement of the Xiangya Hospital of Central South University, the Department of Pediatrics has formulated an action plan with Xiangya unique model to prevent and control NCP among children according to the current epidemic situation and diagnostic and therapeutic program in China. | 2020-02-19 |
| 32053470 | Purpose To determine the change in chest CT findings associated with COVID-19 pneumonia from initial diagnosis until patient recovery. | 2020-02-13 |
| 32057211 | Strategies for prevention and control of NCP include improving epidemic surveillance, quarantining the source of infection, speeding up the diagnosis of suspected cases, optimizing the management of close contacts, tightening prevention and control of cluster outbreaks and hospital infection, preventing possible rebound of the epidemic after people return to work from the Chinese Spring Festival holiday, and strengthening community prevention and control. | 2020-02-14 |
| 32062875 | Chest CT scanning is heplful for early diagnosis. | 2020-02-26 |
| 32065057 | It was believed that 2019-nCoV was transmitted through respiratory tract and then induced pneumonia, thus molecular diagnosis based on oral swabs was used for confirmation of this disease. | 2020-03-16 |
| 32066206 | Rapid diagnosis of concomitant NCP, safe and effective transportation, implementation of the interventional procedure, protection of vascular surgical team and postoperative management and follow-up of such patients have become urgent problems for us. | 2020-02-17 |
| 32074516 | Diagnostic systems for 2019-nCoV were developed with urgency. | 2020-02-19 |
| 32074550 | The drug is recommended to be included in the next version of the Guidelines for the Prevention, Diagnosis, and Treatment of Pneumonia Caused by COVID-19 issued by the National Health Commission of the People’s Republic of China for treatment of COVID-19 infection in larger populations in the future. | 2020-03-18 |
| 32077115 | Detailed clinical investigation of 140 hospitalized COVID-19 cases suggests eosinopenia together with lymphopenia may be a potential indicator for diagnosis. | 2020-02-27 |
| 32077440 | For patients with lung occupying lesions, the whole process of diagnosis and treatment can not be carried out as usual due to the epidemic. […] All thoracic surgeons in China should work together to develop the proper procedures for the diagnosis and treatment in this special situation, and continuously update the recommendations based on epidemic changes and further understanding of COVID-19. | 2020-03-16 |
| 32077441 | With the spread of COVID-19, the routine clinical diagnosis and treatment for lung cancer patients has been disturbed. | 2020-03-16 |
| 32077660 | Clinical classification (mild, moderate, severe, and critical) was carried out according to the diagnosis and treatment program of novel coronavirus pneumonia (Trial Fifth Edition) issued by the National Health Commission. | 2020-02-20 |
| 32080994 | Complying with overall requirements of the government and regulations on public health emergences, as well as the clinical features of diagnosis and treatment of dental illness, this paper refers to previous guidelines and studies on the infection prevention and control in dental diagnosis and treatment in China and foreign countries. | 2020-02-21 |
| 32083985 | Since most COVID-19 infected patients were diagnosed with pneumonia and characteristic CT imaging patterns, radiological examinations have become vital in early diagnosis and assessment of disease course. […] To date, CT findings have been recommended as major evidence for clinical diagnosis of COVID-19 in Hubei, China. | 2020-02-21 |
| 32084676 | Referring to the “Diagnosis and Treatment Scheme for NCP (Trial Version 4 and 5)” and combining the actual practice situation in our hospital with the “Summary of New Coronavirus Files of Shanghai Renji Hospital”, we summarize how to carry out the clinical practice of colorectal surgery under the situation of the prevention and control of the NCP epidemiology, meanwhile under such situation aiming the procedure of diagnose and treatment for emergency patients with colorectal tumor, we share the experiences of the diagnosis of colorectal tumor, the management of patients with colorectal cancer who are scheduled to be admitted for surgery, the protection of wards, the perioperative management. […] The main points are as follows: (1) Multidisciplinary team (MDT) must be run through the diagnosis and treatment of colorectal cancer. | 2020-02-22 |
| 32086886 | The outbreak of the novel coronavirus has affected the normal diagnosis and treatment services in oral medical institutions across the country. | 2020-02-22 |
| 32086938 | Utilizing the Centers for Disease Control and Prevention (CDC, USA) website, and a comprehensive review of PubMed literature, we obtained information regarding clinical signs and symptoms, treatment and diagnosis, transmission methods, protection methods and risk factors for Middle East Respiratory Syndrome (MERS), Severe Acute Respiratory Syndrome (SARS) and COVID-19. | 2020-02-22 |
| 32087623 | Objective: To raise awareness about 2019 novel coronavirus pneumonia (NCP) and reduce missed diagnosis rate and misdiagnosis rate by comparing the clinical characteristics between RNA positive and negative patients clinically diagnosed with NCP. Methods: From January 2020 to February 2020, 54 patients who were newly diagnosed with NCP in Wuhan Fourth Hospital were included in this study. […] Therefore, we should improve the understanding of NCP to prevent missed diagnosis and misdiagnosis; In addition, more rapid and accurate NCP diagnostic approaches should be further developed. 目的： 比较临床诊断新型冠状病毒肺炎（novel coronavirus pneumonia，NCP）核酸检测阳性与阴性患者临床特征的差异，以提高对NCP的认识，降低漏诊及误诊率。 | 2020-02-23 |
| 32088679 | Diagnostic PCR protocols can be found at https://www.who.int/health-topics/coronavirus/laboratory-diagnostics-for-novel-coronavirus. | 2020-03-18 |
| 32088847 | A retrospective review of the patients’ medical history, clinical and laboratory data, as well as imaging findings strongly suggested a diagnosis of COVID-19. […] Although 18F-FDG PET/CT cannot be routinely used in an emergency setting and is generally not recommended for infectious diseases, our pilot data shed light on the potential clinical utility of this imaging technique in the differential diagnosis of complex cases. | 2020-04-03 |
| 32091414 | Computed tomography plays an important role in the diagnosis and evaluation of this emerging global health emergency. | 2020-04-14 |
| 32096367 | However, since COVID-19 was a newly emerging disease, more work was warranted to improve strategies of prevention, diagnosis and treatment for COVID-19. | 2020-03-16 |
| 32096395 | In the central epidemic area of COVID-19, Hubei province, especially Wuhan, the clinical specialists of breast diseases should consider all of the following factors comprehensively: the prevention of COVID-19, the diagnosis and treatment of breast diseases and the accessibility of medical resources. | 2020-02-25 |
| 32096396 | After the outbreak of this disease, the overwhelming majority of cities have launched the “first level response” and the regular diagnosis and treatment of cancer patients are greatly affected. […] The epidemic of novel coronavirus pneumonia poses new challenges to diagnosis and treatment of the patients with digestive system malignancies. | 2020-02-25 |
| 32098019 | Third, ascertainment bias and risk of death among all those infected would be smaller when estimated using shorter virus detection windows and less sensitive diagnostic laboratory tests. | 2020-03-20 |
| 32098302 | The collaborative efforts of researchers are needed to fill the knowledge gaps about this new virus, to develop the proper diagnostic tools, and effective treatment to combat this infection. | 2020-02-26 |
| 32098422 | The goal of this work is to systematically review and compare between SARS-CoV and SARS-CoV-2 in the context of their virus incubation, originations, diagnosis and treatment methods, genomic and proteomic sequences, and pathogenic mechanisms. | 2020-03-23 |
| 32098466 | According to " the Diagnosis and Treatment of New Coronavirus Pneumonia "(6th edition) of the National Health Commission of the People’s Republic of China, a new guideline for the diagnosis and treatment of 2019 novel coronavirus infection suitable for the military (first trial version) was established. […] Some unique opinions and suggestions are put forward in terms of disease name, diagnosis criteria, antiviral treatment, glucocorticoid application, etc. […] This article will make a proper interpretation in order to understand the guideline better and help guide the diagnosis and treatment of diseases. | 2020-02-26 |
| 32099934 | Due to significant variations in the control strategies, which have been changing over time, and thanks to the introduction of detection technologies that have been rapidly improved, enabling to shorten the time from infection/symptoms onset to diagnosis, leading to faster confirmation of the new coronavirus cases, our previous estimations on the transmission risk of the 2019-nCoV need to be revised. | 2020-04-01 |
| 32100980 | Fever patients during chemotherapy need to receive differential diagnosis and screening according to national standards. | 2020-02-26 |
| 32101510 | Background Chest CT is used for diagnosis of 2019 novel coronavirus disease (COVID-19), as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) tests. […] Purpose To investigate the diagnostic value and consistency of chest CT as compared with comparison to RT-PCR assay in COVID-19. […] Conclusion Chest CT has a high sensitivity for diagnosis of COVID-19. | 2020-02-26 |
| 32104917 | Although the virus (severe acute respiratory syndrome coronavirus [SARS-Cov-2]) nucleic acid real-time polymerase chain reaction (PCR) test has become the standard method for diagnosis of SARS-CoV-2 infection, these real-time PCR test kits have many limitations. […] In addition, we evaluated clinical diagnosis results obtained from different types of venous and fingerstick blood samples. | 2020-04-13 |
| 32105637 | Combining assessment of imaging features with clinical and laboratory findings could facilitate early diagnosis of COVID-19 pneumonia. | 2020-04-08 |
| 32107577 | Chest CT examination plays an important role in the initial diagnosis of the novel coronavirus pneumonia. | 2020-04-03 |
| 32108459 | In addition to supporting the frontline actively, medical workers in general surgery spare no efforts in making good diagnosis and treatment of specialized diseases by optimizing treatment process, providing medical advice online, mastering indications of delayed operation and emergency operation reasonably, etc. | 2020-02-28 |
| 32108460 | During the epidemic period, the routine diagnosis and treatment of tumor patients was affected with varying degrees. […] In this special period, we performed the superiority of the multi-disciplinary team of diagnosis and treatment, achieved accurate diagnosis and treatment of patients with hepatobiliary malignant tumors, provided support for these patients with limited medical resources, and helped them to survive during the epidemic period.On the basis of fully understanding the new coronavirus pneumonia, the treatment strategy should be changed timely during the epidemic, and more appropriate treatment methods should be adopted to minimize the adverse effect of the epidemic on tumor treatment. | 2020-02-28 |
| 32109443 | CT scanning provides important bases for early diagnosis and treatment of NCP. | 2020-04-06 |
| 32111114 | According to the guidelines on the diagnosis and treatment of COVID-19 (6(th) trial edition), the latest relative literature at home and abroad, the features of the COVID-19, recommendations for the COVID-19 prevention and control issued by the National Health Commission of China, and management experience of diagnosis and treatment in the related disciplines, we put forward recommendations for the medical practices of burn treatment during the outbreak of the COVID-19 in outpatient and emergency treatment, inpatient treatment, operation and ward management, etc. | 2020-02-29 |
| 32111449 | The reported cases highlight non-specific clinical presentations of 2019 novel coronavirus disease (COVID-19) as well as the importance of rapid laboratory-based diagnosis. | 2020-04-01 |
| 32112549 | Since the outbreak of novel coronavirus pneumonia in December 2019, the diagnosis and treatment of patients with cancer have been facing great challenges. […] Although oncologists are not fighting on the front line to against the epidemic, during this special period, we should not only protect patients, their families and medical staff from the infection of novel Coronavirus, but also minimize the impact of the epidemic on the diagnosis and the treatment of patients with cancer. […] Combining the guidelines for diagnosis and treatment of tumors with our clinical experience, in this epidemic period, we discuss the strategies for diagnosis, treatment, and follow-up of malignant tumors of the digestive system in this article. | 2020-02-29 |
| 32112886 | The information on demographic, epidemiological, clinical, laboratory test for the COVID-19 virus, diagnostic classification, cluster case and outcome were obtained. | 2020-04-06 |
| 32114193 | It might be better to make a diagnosis combining the computed tomography scans and nucleic acid detection. | 2020-04-13 |
| 32116147 | It is feasible that potentially infectious samples may be received in histopathology laboratories for diagnosis. | 2020-03-02 |
| 32118389 | Close contact history of epidemiology, nucleic acid detection and chest imaging are important bases for diagnosis. | 2020-03-02 |
| 32118394 | The diagnosis and treatment of lung cancer patients have been challenged greatly because of extraordinary public health measures since the lung cancer patients are a high-risk population during the COVID-19 outbreak period. | 2020-03-02 |
| 32124995 | These results may help to understand the clinical diagnosis and the changes in clinical parameters of COVID-19. | 2020-03-12 |
| 32125126 | How to make early diagnosis? | 2020-03-03 |
| 32127123 | Since the symptoms are similar to other respiratory infections, differential diagnosis in travellers arriving from countries with wide-spread COVID-19 must include other more common infections such as influenza and other respiratory tract diseases. | 2020-03-18 |
| 32130038 | OBJECTIVE. The objective of our study was to determine the misdiagnosis rate of radiologists for coronavirus disease 2019 (COVID-19) and evaluate the performance of chest CT in the diagnosis and management of COVID-19. […] The CT features of COVID-19 are reported and compared with the CT features of other viruses to familiarize radiologists with possible CT patterns. MATERIALS AND METHODS. This study included the first 51 patients with a diagnosis of COVID-19 infection confirmed by nucleic acid testing (23 women and 28 men; age range, 26-83 years) and two patients with adenovirus (one woman and one man; ages, 58 and 66 years). […] There are differences as well as similarities in the CT features of COVID-19 compared with those of the severe acute respiratory syndrome. CONCLUSION. We found that chest CT had a low rate of missed diagnosis of COVID-19 (3.9%, 2/51) and may be useful as a standard method for the rapid diagnosis of COVID-19 to optimize the management of patients. | 2020-03-04 |
| 32131908 | A bundled approach of active and enhanced laboratory surveillance, early airborne infection isolation, rapid molecular diagnostic testing, and contact tracing for healthcare workers (HCWs) with unprotected exposure in the hospitals was implemented. | 2020-04-09 |
| 32132196 | The highly sensitive and specific COVID-19-RdRp/Hel assay may help to improve the laboratory diagnosis of COVID-19. | 2020-04-01 |
| 32133833 | Objective: To investigate the principles of differential diagnosis of pulmonary infiltrates in cancer patients during the outbreak of novel coronavirus (2019-nCoV) by analyzing one case of lymphoma who presented pulmonary ground-glass opacities (GGO) after courses of chemotherapy. Methods: Baseline demographics and clinicopathological data of eligible patients were retrieved from medical records. | 2020-03-05 |
| 32134116 | We summarize latest literatures on genetic, epidemiological, and clinical features of COVID-19 in comparison to SARS and MERS and emphasize special measures on diagnosis and potential interventions. | 2020-03-31 |
| 32138488 | Diagnosis is confirmed with PCR based testing of appropriate respiratory samples. […] Standard infection control and prevention techniques should be followed. | 2020-03-10 |
| 32141619 | The Chinese government has taken emergency measures to control the outbreak and has undertaken initial steps in the diagnosis and treatment of 2019 novel coronavirus infection disease (COVID-19). […] Our research presents selected available cases of COVID-19 in China to better understand the transmission and diagnosis regarding this infectious disease. | 2020-03-12 |
| 32145185 | This Seminar provides an update on the current knowledge and perspectives on MERS epidemiology, virology, mode of transmission, pathogenesis, diagnosis, clinical features, management, infection control, development of new therapeutics and vaccines, and highlights unanswered questions and priorities for research, improved management, and prevention. | 2020-04-13 |
| 32147731 | We report diagnosis and management of the first laboratory-confirmed case of coronavirus disease 2019 (COVID-19) hospitalized in Toronto, Canada. | 2020-04-03 |
| 32153167 | The National Health Commission, PRC has revised the consensus on diagnosis and treatment seven times in a short period of time, indicating the growing understanding of the disease. […] The diagnosis and differential diagnosis of novel coronavirus pneumonia was facing challenges not only because of large number of tourists increasing dramatically after the relieving of epidemic, but also patients with other diseases return from different areas to search for medical care. […] We were trying to find the similarities and differences among them, and to identify clues to the diagnosis of novel coronavirus pneumonia, so as to ensure accurate diagnosis and treatment. | 2020-03-10 |
| 32155789 | The data will be used for future reference. Methods: From 31 January to 2 February 2020, we conducted an online survey using snowball sampling techniques. | 2020-03-18 |
| 32156330 | The need for timely establishment of diagnostic assays arose when Germany was confronted with the first travel-associated outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Europe. | 2020-03-18 |
| 32156607 | The RT-PCR detection of viral nucleic acid test (NAT) was one of the most quickly established laboratory diagnosis method in a novel viral pandemic, just as in this COVID-19 outbreak. 4880 cases that had respiratory infection symptoms or close contact with COVID-19 patients in hospital in Wuhan, China, were tested for SARS-CoV-2 infection by use of quantitative RT-PCR (qRT-PCR) on samples from the respiratory tract. | 2020-04-14 |
| 32157849 | Objective: To construct and evaluate a diagnosis process for 2019-Corona Virus Disease (COVID-19). Methods: A continuous cohort of adults and adolescent (≥12 years) who screened COVID-19 was included in Xiangya Hospital of Central South University from January 23 to February 3, 2020 in which cases were divided the test library and the verification library. […] The accuracy of CT to make a definite diagnosis was higher than that of epidemiological history, fever, and blood lymph count decline (0.809 vs 0.660, 0.532, 0.596, P=0.001, 0.002, 0.003, respectively). […] The CT-COVID-19 would have reduced the missed diagnosis rate caused by false negative of nucleic acid test (31 vs 64, difference rate 51.6%), the positive rate of nucleic acid test was 64.5% (20/31). | 2020-03-11 |
| 32157862 | Then, chest computed tomography was performed and showed bilateral multifocal ground glass opacities with consolidation which suggested viral pneumonia as a differential diagnosis, and the subsequent 2019-novel coronavirus pneumonia nucleic acid test was positive. | 2020-04-15 |
| 32160149 | A patient in the United States was given a diagnosis of infection with this virus by the state of Washington and the US Centers for Disease Control and Prevention on January 20, 2020. | 2020-03-11 |
| 32161940 | Surveillance of NLR and lymphocyte subsets is helpful in the early screening of critical illness, diagnosis and treatment of COVID-19. | 2020-04-03 |
| 32162699 | However, there is no unified standard for the diagnosis and treatment of COVID-19. […] In the retrospective analysis, we report nine cases of COVID-19, describe the history of contact, clinical manifestations, the course of diagnosis and clinical treatment before, during and after treatment. | 2020-03-16 |
| 32164078 | Based on current studies, the author summarized the clinical characteristics and evolution of the novel viral pneumonia, and proposed the key points of diagnosis and treatment, the scientific management of both confirmed and suspected cases, and the scientific management of disease prevention and control. | 2020-03-13 |
| 32164079 | The novel coronavirus has the characteristics of rapid transmission, atypical clinical symptoms, and easy to affect both lungs, leading to missed diagnosis and misdiagnosis, as well as difficult to detection and assessment at early stage. | 2020-03-13 |
| 32164088 | It needs to emphasize that bronchoscopy should not be used as a routine means for the diagnosis of 2019-nCoV infection sampling. | 2020-03-13 |
| 32164089 | According to the relevant diagnostic criteria, the patients were divided into three groups: mild (15 cases), severe (9 cases) and critical (5 cases). […] High resolution CT is of great value in the differential diagnosis of this disease. | 2020-03-13 |
| 32166607 | Diagnosis is by demonstration of the virus in respiratory secretions by special molecular tests. | 2020-03-23 |
| 32166939 | According to the guidelines drafted by China’s Center for Disease prevention and Control (CDC), the positive nucleic acid test is need to the diagnosis of patient with COVID-19. […] Therefore, which kind of sampling methods should be chosen to help the COVID-19 diagnosis and which way is the most secure for doctors and nurses is our concern. | 2020-03-13 |
| 32167180 | Establishment of the reference sequence for SARS-CoV-2 could benefit not only biological study of this virus but also diagnosis, clinical monitoring and intervention of SARS-CoV-2 infection in the future. | 2020-03-20 |
| 32170559 | This report describes the identification, diagnosis, clinical course, and management of three cases from a family, suggests the expected therapeutic effects of SHL on COVID-19, and warrants further clinical trials. | 2020-03-14 |
| 32170865 | The purpose of this review is primarily to review the pathogen, clinical features, diagnosis, and treatment of COVID-19, but also to comment briefly on the epidemiology and pathology based on the current evidence. | 2020-03-29 |
| 32171740 | The efforts of international health authorities have since focused on rapid diagnosis and isolation of patients as well as the search for therapies able to counter the most severe effects of the disease. | 2020-04-04 |
| 32171872 | The primary endpoint was a negative conversion rate of coronavirus from the date of COVID-19 diagnosis(day7, day14), and assessed whether the pneumonia was progressing or improving by chest CT (day7). […] We analyzed 16 patients who received oral arbidol and LPV/r in the combination group and 17 who oral LPV/r only in the monotherapy group, and both initiated after diagnosis. | 2020-04-16 |
| 32171948 | The detection and diagnosis have been improved as well. | 2020-03-15 |
| 32171952 | This paper aggregates and consolidates the epidemiology, clinical manifestations, diagnosis, treatments and preventions of this new type of coronavirus. | 2020-04-01 |
| 32172228 | As the current gold standard for the etiological diagnosis of SARS-CoV-2 infection is (real time) reverse transcription polymerase chain reaction (rRT-PCR) on respiratory tract specimens, the diagnostic accuracy of this technique shall be considered a foremost prerequisite. […] Some analytical problems may also contribute to jeopardize the diagnostic accuracy, including testing outside the diagnostic window, active viral recombination, use of inadequately validated assays, insufficient harmonization, instrument malfunctioning, along with other specific technical issues. […] Some practical indications can hence be identified for minimizing the risk of diagnostic errors, encompassing the improvement of diagnostic accuracy by combining clinical evidence with results of chest computed tomography (CT) and RT-PCR, interpretation of RT-PCR results according to epidemiologic, clinical and radiological factors, recollection and testing of upper (or lower) respiratory specimens in patients with negative RT-PCR test results and high suspicion or probability of infection, dissemination of clear instructions for specimen (especially swab) collection, management and storage, together with refinement of molecular target(s) and thorough compliance with analytical procedures, including quality assurance. | 2020-04-01 |
| 32172669 | To standardize the diagnosis and treatment of this new infectious disease, an operational recommendation for the diagnosis and management of SARS-CoV-2 infection is developed by Peking Union Medical College Hospital. | 2020-03-17 |
| 32174057 | Owing to the complications of COVID-19 pneumonia, the first symptom and imaging features of patients can be very atypical and early diagnosis of COVID-19 infections remains a challenge. | 2020-03-16 |
| 32174096 | Objective: To explore the management strategies for patients with gynecological malignant tumors during the outbreak and transmission of COVID19. Methods: We retrospectively analyzed the clinical characteristics, treatment, and disease outcomes of three patients with gynecological malignancies associated with COVID19 in Renmin Hospital of Wuhan University in January 2020, and proposed management strategies for patients with gynecological tumors under risk of COVID19. Results: Three patients were treated COVID19 based on the national diagnosis and treatment protocol as well as research progress. […] While actively preventing and controlling COVID-19, the diagnosis and treatment of gynecological malignant tumors should be carried out in an orderly and safe manner. 目的： 在新型冠状病毒肺炎(COVID-19)暴发和传播期间，探讨妇科恶性肿瘤患者的管理策略。 | 2020-03-16 |
| 32174267 | In this study, we illustrated the importance of combining molecular diagnostics to rule out common pathogens and performed mNGS to obtain unbiased potential pathogen result for the diagnosis of UP. | 2020-03-17 |
| 32179660 | The epidemic curves were constructed by key dates of disease onset and case diagnosis. […] Onset-to-diagnosis curves were constructed by fitting a log-normal distribution to data on both onset and diagnosis dates. | 2020-04-09 |
| 32179908 | We report a 55-day-old case with COVID-19 confirmed in China and describe the identification, diagnosis, clinical course, and treatment of the patient, including the disease progression from day 7 to day 11 of illness. | 2020-03-17 |
| 32180140 | We should attach importance to early recognition, early diagnosis, and early treatment of infected children. | 2020-03-17 |
| 32181488 | We evaluated the correlation of domestic air traffic to the number of confirmed COVID-19 cases and determined the growth curves of COVID-19 cases within China before and after lockdown as well as after changes in COVID-19 diagnostic criteria. […] A further increase is detected after changing diagnostic and testing methodology to 19.3 (95% CI: 15.1-26.3), respectively. | 2020-03-17 |
| 32181807 | The median of incubation period was 6 (IQR, 3-8) days and the median time from first visit to a doctor to confirmed diagnosis was 1 (1-2) days. | 2020-03-17 |
| 32181911 | The role of clinical laboratory data in the differential diagnosis of the severe forms of COVID-19 has not been definitely established. | 2020-04-10 |
| 32183901 | In this scoping review, 65 research articles published before 31 January 2020 were analyzed and discussed to better understand the epidemiology, causes, clinical diagnosis, prevention and control of this virus. […] During this early period, published research primarily explored the epidemiology, causes, clinical manifestation and diagnosis, as well as prevention and control of the novel coronavirus. | 2020-03-19 |
| 32185921 | If the diagnosis and treatment of malaria cases as well as the investigation and response of the epidemic foci are not carried out timely, it may endanger patients’lives and cause the possible of secondary transmission, which threatens the achievements of malaria elimination in China. […] Due to the extensive spread and high transmission ability of the COVID-19, there is a possibility of virus infections among malaria cases during the medical care-seeking behaviors and among healthcare professionals during clinical diagnosis and treatment, sample collection and testing and epidemiological surveys. | 2020-03-19 |
| 32187887 | The World Health Organization confirmed this diagnosis and named the pathogen SARSCoV-2. […] From the perspective of clinical pediatricians as the first line fighting the epidemic, this paper will discuss the clinical characteristics, prevention and control measures, outcomes, diagnosis, and treatment of pediatric cases. | 2020-04-16 |
| 32187921 | Rapid diagnosis of concomitant COVID-19, safe and effective transportation, implementation of the interventional procedure, protection of vascular surgical team and postoperative management and follow-up of such patients have become urgent problems for us. | 2020-03-19 |
| 32187929 | After the outbreak of this disease, Chinese scientists invested a lot of energy to carry out research by developing rapid diagnostic reagents, identifying the characters of the pathogen, screening out clinical drugs that may inhibit the virus, and are rapidly developing vaccines. | 2020-03-19 |
| 32189015 | Diagnosis relies on PCR using specimens from the respiratory tract. | 2020-04-10 |
| 32189175 | Knowledge of CT characteristics of COVID-19 pneumonia might be helpful to the early diagnosis and treatment of patients, and to control the spread of infection. | 2020-03-19 |
| 32190290 | Here we highlight nine most important research questions concerning virus transmission, asymptomatic and presymptomatic virus shedding, diagnosis, treatment, vaccine development, origin of virus and viral pathogenesis. | 2020-03-22 |
| 32191587 | Background CT may play a central role in the diagnosis and management of COVID-19 pneumonia. | 2020-03-19 |
| 32191588 | Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), sensitivity and specificity. | 2020-03-19 |
| 32191623 | Despite there being evidence that laboratory tests are vital throughout many clinical pathways, there are at least three major areas where in vitro diagnostics can also provide essential contributions to diagnostic reasoning and managed care of patients with suspected or confirmed SARS-CoV-2 infection. […] These include etiological diagnosis, patient monitoring, as well as epidemiologic surveillance. | 2020-04-01 |
| 32191813 | The World Health Organization recommends a combination of measures: rapid diagnosis and immediate isolation of cases, rigorous tracking and precautionary self-isolation of close contacts. | 2020-03-25 |
| 32192296 | Although colorectal surgery is not a front-line subject in the fight against the epidemic, but in this special situation, it is a difficult task to provide the highest quality medical services and ensure the orderly clinical work, on the premise of maximizing the protection for patients and their families, health of medical staff, and the safety of wards and hospitals, We summarize how to carry out the clinical practice of colorectal surgery under the situation of the prevention and control of the COVID-19 epidemiology, including the procedures of diagnose and treatment for emergency patients with colorectal tumor, and share the experiences of the diagnosis of colorectal tumor, the management of patients with colorectal cancer who are scheduled to be admitted for surgery, the protection of wards, the perioperative management. […] The main points are as follows: (1) Multidisciplinary team (MDT) must be run through the diagnosis and treatment of colorectal cancer. | 2020-03-23 |
| 32192297 | Fever patients during chemotherapy need to receive differential diagnosis and screening according to national standards. | 2020-03-23 |
| 32193037 | We analyzed the initial and follow-up CT features of patients with disease severity, according to the Guidelines for the Diagnosis and Treatment of New Coronavirus Pneumonia. | 2020-04-10 |
| 32193638 | In diagnosis, chest computed tomography (CT) manifestations can supplement parts of limitations of real-time reverse transcription polymerase chain reaction (RT-PCR) assay. […] Based on a comprehensive literature review and the experience in the frontline, we aim to review the typical and relatively atypical CT manifestations with representative COVID-19 cases at our hospital, and hope to strengthen the recognition of these features with radiologists and help them make a quick and accurate diagnosis.Key Points • Ground glass opacities, consolidation, reticular pattern, and crazy paving pattern are typical CT manifestations of COVID-19. | 2020-03-30 |
| 32195698 | Here, the authors review COVID-19 pathogenesis, presentation, diagnosis, and potential therapeutics, with a focus on management of COVID-19-associated respiratory failure. | 2020-04-16 |
| 32196032 | Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents. | 2020-03-20 |
| 32196430 | The three unprecedented outbreaks of emerging human coronavirus (HCoV) infections at the beginning of the twenty-first century have highlighted the necessity for readily available, accurate and fast diagnostic testing methods. […] The laboratory diagnostic methods for human coronavirus infections have evolved substantially, with the development of novel assays as well as the availability of updated tests for emerging ones. […] Several integrated, random-access, point-of-care molecular devices are currently under development for fast and accurate diagnosis of SARS-CoV-2 infections. | 2020-04-07 |
| 32196678 | Laboratory detection of the viral nucleic acid can yield false-negative results, and serological testing of virus-specific IgG and IgM antibodies should be used as an alternative for diagnosis. | 2020-04-06 |
| 32198191 | It includes a description of hazard group 3 organisms, the category to which SARS-CoV-2 has been assigned, a brief description of what is currently known about the pathological and autopsy findings in COVID-19, a summary of the recommendations for conducting autopsies in suspected COVID-19 cases and the techniques for making the diagnosis at autopsy. | 2020-04-02 |
| 32198501 | The diagnostic value of IgM was evaluated in this cohort. […] Humoral response to SARS-CoV-2 can aid to the diagnosis of COVID-19, including subclinical cases. | 2020-03-21 |
| 32198915 | Clinicians need to comprehensively analyze the epidemic history, disease onset characteristics, clinical manifestations, image characteristics, serological andpathogenic microorganism test results to confirm diagnosis. […] Because of this, the article will discuss the issues related to the differential diagnosis and management of COVID-19 and ILD, and try to provide reasonable suggestions. | 2020-03-21 |
| 32198986 | But so far, the pathological diagnosis of COVID-19 has been relatively deficient： it is still confined to the pathological findings of punctured organs, and the majority of medical workers have poor awareness of its pathological characteristics. | 2020-04-08 |
| 32201353 | Based on the current published evidence, we systematically summarizes the epidemiology, clinical characteristics, diagnosis, treatment and prevention of knowledge surrounding COVID-19. | 2020-04-16 |
| 32202343 | Diagnostic findings have been similar to adults, with fever and respiratory symptoms being prevalent, but fewer children seem to have developed severe pneumonia. | 2020-04-14 |
| 32202646 | Frontline health care workers engaged in direct diagnosis, treatment, and care of patients with COVID-19 were associated with a higher risk of symptoms of depression (OR, 1.52; 95% CI, 1.11-2.09; P = .01), anxiety (OR, 1.57; 95% CI, 1.22-2.02; P < .001), insomnia (OR, 2.97; 95% CI, 1.92-4.60; P < .001), and distress (OR, 1.60; 95% CI, 1.25-2.04; P < .001). […] In this survey of heath care workers in hospitals equipped with fever clinics or wards for patients with COVID-19 in Wuhan and other regions in China, participants reported experiencing psychological burden, especially nurses, women, those in Wuhan, and frontline health care workers directly engaged in the diagnosis, treatment, and care for patients with COVID-19. | 2020-04-01 |
| 32202911 | Gastrointestinal (GI) endoscopy is a high-risk diagnostic-therapeutic procedure in the case of upper GI examinations, and a moderate to low-risk intervention when involving lower GI explorations. | 2020-03-23 |
| 32204750 | With the spread of coronavirus disease 2019 (COVID-19) and growing knowledge of its diagnosis and treatment, it has been clear that children are also susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). | 2020-03-26 |
| 32204756 | Infants and young children with COVID-19 tend to have mild clinical symptoms and imaging findings not as typical as those of adults, and therefore, the diagnosis of COVID-19 should be made based on imaging findings along with epidemiological history and nucleic acid detection. […] Chest CT has guiding significance for the early diagnosis of asymptomatic children. | 2020-03-26 |
| 32204757 | This article reports the diagnosis and treatment of twin girls who were diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Hunan Province, China. | 2020-03-26 |
| 32205090 | This ward houses patients exhibiting atypical manifestations or awaiting definitive diagnosis. | 2020-04-16 |
| 32205269 | Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases. […] We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. | 2020-04-10 |
| 32207068 | There is still an urgent need to accelerate protocols that lead to the implementation of rapid point-of-care diagnostic testing and effective antiviral therapies. | 2020-04-09 |
| 32207542 | Mobilize research platforms for patient needs: Leverage our relationships with participants and rapidly deploy novel clinical engagement techniques such as digital tools to intervene remotely and reduce the negative effects of social isolation on our participants. | 2020-04-03 |
| 32207591 | A total of 67 patients diagnosed as COVID-19 by nucleic acid testing were included and divided into 4 groups according to the clinical staging based on Diagnosis and treatment of novel coronavirus pneumonia (Trial version 6). | 2020-03-26 |
| 32211920 | Diagnosis relies on PCR using specimens from the respiratory tract. | 2020-03-26 |
| 32211963 | If these typical alterations are found, then the differential diagnosis of coronavirus disease 2019 must be considered. | 2020-03-30 |
| 32213269 | The interval from onset to diagnosis for the first case was longer than those of other cases in the familial clusters (Z=-2.406, P= 0.016). […] The intervals from onset to diagnosis were significant different among the family, working place and public place clusters (H=8.843, , P=0.012) , and there were also significant differences in onset time among the secondary cases (H=16.607, P=0.000) . Conclusions: In the surveillance of COVID-19 epidemic, special attention should be paid to the cases from same family, same work place, or other places where clustering are prone to occur, and the epidemiological investigation should be carried out timely to confirm the cluster. | 2020-03-27 |
| 32213270 | The median of onset- diagnosis interval of the initial cases was 6 (3-9) days, and the median of onset-diagnosis interval of the secondary cases was 5 (3-8) days. Conclusions: Epidemic clusters of COVID-19 were common in many cities outside Wuhan and Hubei. […] After 4 February, the epidemic clusters were mainly caused by the first generation or second generation cases in local areas, and the time for diagnosis became shorter. 目的： 了解新型冠状病毒肺炎聚集性病例的流行病学特征，探讨家庭因素以及集体活动等对本病传播的影响。 | 2020-03-27 |
| 32213337 | Serological assay can complement RT-qPCR for diagnosis. | 2020-04-16 |
| 32215691 | ROC was used to test the diagnosis ability of TSS for severe-critical type. | 2020-03-30 |
| 32216961 | Spiral CT is a sensitive examination method, which can be applied to make an early diagnosis and for evaluation of progression, with a diagnostic sensitivity and accuracy better than that of nucleic acid detection. | 2020-04-10 |
| 32217113 | Here we present a review of COVID-19 in pregnancy, bringing together the various factors integral to the understanding of pathophysiology and susceptibility, diagnostic challenges with real-time reverse transcriptase polymerase chain reaction (RT-PCR) assays, therapeutic controversies, intrauterine transmission and maternal-fetal complications. | 2020-03-28 |
| 32217506 | However, some countries remain ill-equipped, have poor diagnostic capacity, and are in need of further capacity development in response to public health threats. | 2020-04-03 |
| 32217556 | Among a cohort of 799 patients, 113 who died and 161 who recovered with a diagnosis of covid-19 were analysed. | 2020-04-06 |
| 32219006 | The confirmation rate of Wuhan estimated by our model is 0.0643, substantially lower than that of Hubei excluding Wuhan (0.1914), and that of China excluding Hubei (0.2189), but it jumps to 0.3229 after February 12 when clinical evidence was adopted in new diagnosis guidelines. | 2020-03-31 |
| 32219626 | Based on the New Diagnosis and Treatment Scheme for Novel Coronavirus Infected Pneumonia (Trial Edition 5), combined with our current clinical treatment experience, we recently proposed a revision of the first edition of “Guidance for maternal and fetal management during pneumonia epidemics of novel coronavirus infection in the Wuhan Tongji Hospital”. […] This article focused on the issues of greatest concern of pregnant women including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnostic criteria, inspection precautions, drug treatment options, indications and methods of termination of pregnancy, postpartum fever, breastfeeding considerations, mode of mother-to-child transmission, neonatal isolation and advice on neonatal nursing, to provide valuable experience for better management of SARS-CoV-2 infection in pregnant women and newborns. | 2020-03-28 |
| 32219814 | In view of the seriousness of the COVID-19 epidemic, a series of prevention and control measures adopted by the government have restricted the follow-up, diagnosis and treatment of patients by the hospitals, which has a great impact on their mental and physical health. | 2020-04-02 |
| 32219885 | We also found that the RT-PCR results from several tests at different points were variable from the same patients during the course of diagnosis and treatment of these patients. […] Our results indicate that in addition to the emphasis on RT-PCR testing, clinical indicators such as computed tomography images should also be used not only for diagnosis and treatment but also for isolation, recovery/discharge, and transferring for hospitalized patients clinically diagnosed with COVID-19 during the current epidemic. […] These results suggested the urgent needs for the standard of procedures of sampling from different anatomic sites, sample transportation, optimization of RT-PCR, serology diagnosis/screening for SARS-CoV-2 infection, and distinct diagnosis from other respiratory diseases such as fluenza infections as well. | 2020-04-05 |
| 32220177 | Meanwhile, rapid detection kit for serological monitoring of the virus in general population is expected so as to achieve early detection, early diagnosis, early isolation and early treatment. | 2020-04-02 |
| 32220181 | The epidemiological and clinical features could provide quicker diagnosis and better management for the COVID-19 infected patients. | 2020-04-02 |
| 32221117 | COVID-19 can complicate the perioperative course with diagnostic challenge and a high potential fatality rate. | 2020-03-29 |
| 32221519 | Combining RNA and antibody detections significantly improved the sensitivity of pathogenic diagnosis for COVID-19 (p<0.001), even in early phase of 1-week since onset (p=0.007). […] The findings provide strong empirical support for the routine application of serological testing in the diagnosis and management of COVID-19 patients. | 2020-03-29 |
| 32221523 | The widely used reverse transcription PCR (RT-PCR) method has limitations for clinical diagnosis and treatment. | 2020-03-29 |
| 32222119 | Therefore, the protective measures are necessary on admission; the instant CT scan and real-time reverse-transcriptase polymerase-chain-reaction assay should be helpful in early diagnosis and avoid cross-infection on the occasion that patients have fever and other respiratory signs. | 2020-04-10 |
| 32222720 | Practical work experience in our spinal outpatient and emergency department during the COVID-19 pandemic is summarized in this article, with combined evidence-based medical evidence to explore a standardized process of diagnosis and treatment for spinal diseases. | 2020-04-07 |
| 32222812 | The topics were: (1) infection control, (2) laboratory diagnosis and specimens, (3) hemodynamic support, (4) ventilatory support, and (5) COVID-19 therapy. | 2020-04-02 |
| 32222988 | Diarrhoea was the most common gastrointestinal symptom in children and adults, with a mean duration of 4.1 ± 2.5 days, and was observed before and after diagnosis. | 2020-04-16 |
| 32222992 | All of these three cases experienced mild illness and recovered soon after the treatment, with the nucleic acid of throat swab turning negative within 14, 11, and 7 days after diagnosis, respectively. | 2020-04-15 |
| 32223004 | Dermatoscope is a convenient diagnostic tool used by dermatologists in the diagnosis of skin, hair and nail disorders. | 2020-03-30 |
| 32223179 | The aim of this review article is to inform the audience of diagnostic and surveillance technologies for SARS-CoV-2 and their performance characteristics. | 2020-04-10 |
| 32223665 | OBJECTIVE. This study aims to assess correlations of the time from symptom onset to diagnosis and treatment with the time to disease resolution and CT scores as based on findings from sequential chest CT examinations. MATERIALS AND METHODS. Thirty patients with coronavirus disease (COVID-19) confirmed by reverse transcription-polymerase chain reaction analysis underwent chest CT examinations. […] The time from symptom onset to diagnosis and treatment was recorded for each patient, and on the basis of this information, patients with COVID-19 were divided into group 1 (patients for whom this interval was ≤ 3 days) and group 2 (those for whom this interval was > 3 days). […] The differences in age, sex, and last CT scores determined before discharge between the two groups were analyzed, and correlations of the time from symptom onset to diagnosis and treatment with the time to disease resolution as well as with the highest CT score also underwent statistical analysis. RESULTS. A total of 25 subjects were enrolled in the study. […] The time from symptom onset to diagnosis and treatment had a positive correlation with the time to disease resolution (r = 0.93; p = 0.000) as well as with the highest CT score (r = 0.83; p = 0.006). CONCLUSION. Timely diagnosis and treatment are key to providing a better prognosis for patients with COVID-19. | 2020-03-31 |
| 32224769 | The topics were: 1) infection control, 2) laboratory diagnosis and specimens, 3) hemodynamic support, 4) ventilatory support, and 5) COVID-19 therapy. | 2020-03-31 |
| 32225135 | Simplification of the diagnostic and staging pathway has to be prioritized in order to reduce hospital visits and consequently the risk of contagion. | 2020-03-31 |
| 32226287 | Based on our data on SARS-CoV-2 RNA shedding in stool and the possibility of a lag in viral detection in NPS specimens, the assessment of both fecal and respiratory specimen is recommended to enhance diagnostic sensitivity, and also to aid discharge decision before the role of viral RNA shedding in stool is clarified. | 2020-04-03 |
| 32226295 | We will cover the basics about the epidemiology, etiology, virology, diagnosis, treatment, prognosis, and prevention of the disease. | 2020-04-03 |
| 32226962 | Our unique case underscores the increasing diversity of COVID-19 presentations and potential for initial mis- diagnosis and delay in implementing proper precautions. | 2020-04-01 |
| 32227197 | Diagnosis of COVID-19 is currently confirmed with PCR based testing of appropriate respiratory samples. […] Since this case, any patient with severe disease (eg, ARDS or pneumonia) requiring hospitalization without an explanatory diagnosis can be tested even if no clear source of exposure is identified. […] While influencing national health policies for revising screening criteria, this case also highlighted significant knowledge gaps in diagnosis and treatment and a desperate need for early, widespread, fast and cheap testing for COVID-19. | 2020-04-01 |
| 32227494 | After patient recovery, a chest CT examination, combined with SARS-CoV-2 RNA detection, confirmed diagnosis. | 2020-03-31 |
| 32228809 | These findings might also serve as a practical reference for clinical diagnosis and medical treatment. | 2020-04-01 |
| 32229107 | We report the dynamic change process of target genes by RT-PCR testing of SARS-Cov-2 during the course of a COVID-19 patient: from successive negative results to successive single positive nucleocapsid gene, to two positive target genes (orf1ab and nucleocapsid) by RT-PCR testing of SARS-Cov-2, and describe the diagnosis, clinical course, and management of the case. | 2020-04-16 |
| 32229322 | To evaluate the diagnostic value of computed tomography (CT) and real-time reverse-transcriptase-polymerase chain reaction (rRT-PCR) for COVID-19 pneumonia. […] For patients with a final confirmed diagnosis, clinical and laboratory data, in addition to CT imaging findings were evaluated. | 2020-04-16 |
| 32229605 | Background: At present, PCR-based nucleic acid detection cannot meet the demands for coronavirus infectious disease (COVID-19) diagnosis.Methods: 214 confirmed COVID-19 patients who were hospitalized in the General Hospital of Central Theater Command of the People’s Liberation Army between January 18 and February 26, 2020, were recruited. […] Two Enzyme-Linked Immunosorbent Assay (ELISA) kits based on recombinant SARS-CoV-2 nucleocapsid protein (rN) and spike protein (rS) were used for detecting IgM and IgG antibodies, and their diagnostic feasibility was evaluated.Results: Among the 214 patients, 146 (68.2%) and 150 (70.1%) were successfully diagnosed with the rN-based IgM and IgG ELISAs, respectively; 165 (77.1%) and 159 (74.3%) were successfully diagnosed with the rS-based IgM and IgG ELISAs, respectively. […] The positive rate of rN-based and rS-based IgM and IgG ELISAs was less than 60% during the early stage of the illness 0-10 d.p.o., and that of IgM and IgG was obviously increased after 10 d.p.o.Conclusions: ELISA has a high sensitivity, especially for the detection of serum samples from patients after 10 d.p.o, it can be an important supplementary method for COVID-19 diagnosis. | 2020-04-01 |
| 32229732 | All these patients did not meet the diagnostic criteria of AKI. | 2020-04-01 |
| 32232230 | As one of the busiest specialised hospitals in the world, the Department of Oral and Maxillofacial Surgery of Peking University School and Hospital of Stomatology summarised the experience with disease prevention and control and clinical recommendations on the examination, diagnosis and treatment processes, clinical management, healthcare personnel protection and disinfection amid the continued spread of the pandemic. | 2020-04-02 |
| 32232423 | Because of the rapid spread of this disease through respiratory droplets, health care workers who come in close contact with the upper aerodigestive tract during diagnostic and therapeutic procedures, such as otolaryngologists-head and neck surgeons, are particularly at risk. | 2020-04-01 |
| 32232433 | Understanding ocular manifestations of patients with COVID-19 by ophthalmologists and others may facilitate the diagnosis and prevention of transmission of the disease. | 2020-04-04 |
| 32232648 | To evaluate the diagnostic performance of chest CT to differentiate coronavirus disease 2019 (COVID-19) pneumonia in non-high-epidemic area in Japan. […] Using a Likert scale and its receiver operating characteristic curve analysis, two radiologists (R1/R2) evaluated the diagnostic performance of the five CT criteria: (1) ground glass opacity (GGO)-predominant lesions, (2) GGO- and peripheral-predominant lesions, (3) bilateral GGO-predominant lesions; (4) bilateral GGO- and peripheral-predominant lesions, and (5) bilateral GGO- and peripheral-predominant lesions without nodules, airway abnormalities, pleural effusion, and mediastinal lymphadenopathy. […] The five CT criteria showed moderate to excellent diagnostic performance with area under the curves (AUCs) ranging 0.77-0.88 for R1 and 0.78-0.92 for R2. | 2020-04-01 |
| 32232837 | Pre-existing primary headache diagnosis was present in about a third [46/158 (29.1%)] of respondents. […] A pre-existing primary headache diagnosis (OR = 4.20, 95% CI 1.48-15.40; P = .030) and combined PPE usage for >4 hours per day (OR 3.91, 95% CI 1.35-11.31; P = .012) were independently associated with de novo PPE-associated headaches. […] Since COVID-19 outbreak, 42/46 (91.3%) of respondents with pre-existing headache diagnosis either “agreed” or “strongly agreed” that the increased PPE usage had affected the control of their background headaches, which affected their level of work performance. | 2020-04-13 |
| 32233563 | Delay in diagnosis and limited hospital resources lead to a rapid spread of COVID-19. […] In this study, we investigate the effect of delay in diagnosis on the disease transmission with a new formulated dynamic model. […] Sensitivity analyses and numerical simulations reveal that, improving the proportion of timely diagnosis and shortening the waiting time for diagnosis can not eliminate COVID-19 but can effectively decrease the basic reproduction number, significantly reduce the transmission risk, and effectively prevent the endemic of COVID-19, e.g., shorten the peak time and reduce the peak value of new confirmed cases and new infection, decrease the cumulative number of confirmed cases and total infection. | 2020-04-09 |
| 32233876 | Emergency trauma radiology, although a relatively new subspecialty of radiology, plays a critical role in both the diagnosis/triage of acutely ill patients, but even more important in providing leadership and taking the lead in the preparedness of imaging departments in dealing with novel highly infectious communicable diseases and mass casualties. […] We discuss roles that community radiology clinics, outpatient radiology departments, and emergency radiology departments can play in the diagnosis of this disease. | 2020-04-02 |
| 32233973 | Satisfactory outcome was observed in one mild case and one severe case of COVID-19 pneumonia after the use of the online/offline multidisciplinary quarantine observation form, online monitoring, and classified diagnosis and treatment, as well as strict compliance with quarantine measures. | 2020-04-02 |
| 32233980 | Furthermore, rapid and effective stroke care remains paramount to achieve maximal functional recovery for those needing admission and to triage care appropriately for those who may be presenting with neurological symptoms but have an alternative diagnosis. | 2020-04-02 |
| 32234126 | The diagnosis of COVID-19 is based on the positive of etiological test. | 2020-04-02 |
| 32234127 | Also, the incubation period prolonged along with the epidemic stage (F=51.65, P<0.01), but the intervals between disease onset and hospital visit (F=5.32, P<0.01), disease onset and diagnosis (F=5.25, P<0.01) became shorter along with the epidemic stage. | 2020-04-02 |
| 32234465 | To effectively implement epidemic prevention, early identification and diagnosis are critical to disease control. | 2020-04-15 |
| 32234468 | Early diagnosis, quarantine, and supportive treatments are essential to cure patients. […] This paper reviews the literature on all available information about the epidemiology, diagnosis, isolation and treatments of COVID-19. | 2020-04-09 |
| 32235517 | Whereas diagnostic or infrastructural technology is an expensive investment with long-term payback, leapfrogging digital applications reduce contingent costs. “Digital” savings can be shared by key stakeholders with P4P schemes, incentivizing value co-creation patterns. | 2020-04-02 |
| 32237160 | Chinese medical staff have summarized a set of effective strategies and methods in the diagnosis and treatment of this disease that are worthy of reference for their international counterparts. | 2020-04-10 |
| 32237278 | The ability to rapidly identify, propagate, and internationally share our SARS-CoV-2 isolate is an important step in collaborative scientific efforts to deal effectively with this international public health emergency by developing better diagnostic procedures, vaccine candidates, and antiviral agents. | 2020-04-05 |
| 32237288 | COVID-19 is a severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and real-time reverse transcription-PCR is currently the most reliable diagnostic method for COVID-19 around the world. […] These guidelines are based on other related domestic and international guidelines, as well as expert opinions and include the selection of test subjects, selection of specimens, diagnostic methods, interpretation of test results, and biosafety. | 2020-04-02 |
| 32238024 | A lower respiratory tract specimen should be obtained for better diagnosis of corona virus disease 2019, even in the absence of respiratory symptoms for patients with significant travel or exposure history. | 2020-04-16 |
| 32238223 | Diagnosis in this patient was facilitated by chest imaging and repeat viral testing. […] Thus, chest imaging studies might enhance capabilities for early diagnosis of COVID-19 pneumonia. | 2020-04-02 |
| 32238224 | The Importance of Diagnostic Testing during a Viral Pandemic: Early Lessons from Novel Coronavirus Disease (COVID-19). | 2020-04-02 |
| 32238260 | Thus leading to a delay in the diagnosis of COVID-19 infection and further spread of the virus, since in most cases of Dengue there are no warning signs and treatment is ambulatory. | 2020-04-08 |
| 32238336 | The response strategy included early diagnosis, patient isolation, symptomatic monitoring of contacts as well as suspected and confirmed cases, and public health quarantine. | 2020-04-09 |
| 32238612 | Diagnosis involves a combination of clinical and epidemiological features with laboratory confirmation. | 2020-04-16 |
| 32238615 | Perinatal period poses unique challenges and care of the mother-baby dyads requires special resources for prevention of transmission, diagnosis of infection and providing clinical care during labor, resuscitation and postnatal period. […] To provide recommendations for prevention of transmission, diagnosis of infection and providing clinical care during labor, resuscitation and postnatal period. […] A set of twenty recommendations are provided under the following broad headings: 1) pregnant women with travel history, clinical suspicion or confirmed COVID-19 infection; 2) neonatal care; 3) prevention and infection control; 4) diagnosis; 5) general questions. | 2020-04-02 |
| 32238757 | Currently, various diagnostic kits to test for COVID-19 are available and several repurposing therapeutics for COVID-19 have shown to be clinically effective. […] Here, we review the current status of epidemiology, diagnosis, treatment, and vaccine development for COVID-19. | 2020-04-10 |
| 32239472 | To subjectively and objectively evaluate the feasibility and diagnostic reliability of a low-dose, long-pitch dual-source chest CT protocol on third-generation dual-source CT (DSCT) with spectral shaping at 100Sn kVp for COVID-19 patients. […] Qualitative analysis demonstrated significant reduction in motion artifacts (p = 0.031) with comparable diagnostic reliability between HD-DECT and LDCT. […] Ultra-low-dose, dual-source, fast CT protocol provides highly diagnostic images for COVID-19 with potential for reduction in dose and motion artifacts. | 2020-04-14 |
| 32240285 | Contacts were persons exposed to the case on or after the day before case diagnostic specimen collection. […] Specimens collected 18 days after diagnosis tested positive. […] This report demonstrates that SARS-CoV-2 infection can cause mild illness and result in positive tests for up to 18 days after diagnosis, without evidence of transmission to close contacts. | 2020-04-02 |
| 32241244 | To date, computed tomography (CT) findings have been recommended as major evidence for the clinical diagnosis of COVID-19 in Hubei, China. […] Since most patients with COVID-19 infection share typical imaging features, radiological examinations have an irreplaceable role in screening, diagnosis and monitoring treatment effects in clinical practice. | 2020-04-03 |
| 32241316 | Early diagnosis is one of the important contents in prevention and control. […] COVID-19 patients with early mild pneumonia often lack typical evidence to make a definitive diagnosis. […] Based on the analysis of the cases of 4 patients, this article finds that early diagnosis requires a combination of epidemiology, clinical manifestations, imaging, and etiology, with particular emphasis on epidemiology history and chest CT manifestations. | 2020-04-03 |
| 32241761 | 4 959 790 Chinese students aged 6 to 22 years with a diagnosis of any of 44 notifiable infectious diseases. […] Diagnosis of, and deaths from, 44 notifiable infectious diseases. | 2020-04-08 |
| 32242438 | Diagnosis is made by a RT-PCR test using respiratory secretions, usually nasopharyngeal and oropharyngeal swabs. | 2020-04-08 |
| 32242947 | We aim to explore reliable evidence for the diagnosis and treatment of the COVID-19 by analyzing all the published studies by Chinese scholars on the clinical and imaging features in novel coronavirus pneumonia caused by SARS-CoV-2. | 2020-04-10 |
| 32243238 | Background The standard for diagnosis of SARS-CoV-2 virus is reverse transcription polymerase chain reaction (RT-PCR) test, but chest CT may play a complimentary role in the early detection of COVID-19 pneumonia. […] Diagnostic performance of CT was calculated using RT-PCR as reference. | 2020-04-03 |
| 32243288 | This has led the United States to declare a national emergency and a ban on all elective diagnostic and therapeutic procedures, as well as elective surgery in inpatient and outpatient settings. […] However, these facilities may be able assist acute care hospitals, as essential (urgent and emergent) surgeries and diagnostic and therapeutic procedures will still need to be performed. | 2020-04-03 |
| 32243697 | After the diagnosis of COVID-19, immunosuppressive agents were discontinued and methylprednisolone with prophylactic antibiotics were initiated, however, the lung injury progressed. | 2020-04-03 |
| 32245150 | In the absence of effective vaccines, infection prevention and control through diagnostic testing and quarantine are critical. […] Early detection and differential diagnosis of PEDV infections increase the chance of successful control of the disease. […] Particularly, the bridge assay constitutes a rapid diagnostic that substantially improves upon the “time to result” metric of currently available immunoassays. | 2020-04-06 |
| 32245395 | In this Commentary, we would like to comment on the article titled “A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)” as a featured article in Military Medical Research. | 2020-04-10 |
| 32245396 | On 6 February 2020, our team had published a rapid advice guideline for diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infection, and this guideline provided our experience and make well reference for fighting against this pandemic worldwide. […] However, the coronavirus disease 2019 (COVID-19) is a new disease, our awareness and knowledge are gradually increasing based on the ongoing research findings and clinical practice experience; hence, the strategies of diagnosis and treatment are also continually updated. […] In this letter, we answered one comment on our guideline and provided the newest diagnostic criteria of “suspected case” and “confirmed case” according to the latest Diagnosis and Treatment Guidelines for COVID-19 (seventh version) that issued by the National Health Committee of the People’s Republic of China. | 2020-04-10 |
| 32245835 | This commentary covers current issues and challenges for the laboratory diagnosis of infections caused by SARS-CoV-2. […] In the pre-analytical stage, collecting the proper respiratory tract specimen at the right time from the right anatomic site is essential for a prompt and accurate molecular diagnosis of COVID-19. […] In the analytic stage, real-time RT-PCR assays remain the molecular test of choice for the etiologic diagnosis of SARS-CoV-2 infection while antibody-based techniques are being introduced as supplemental tools. […] Finally, random access, integrated devices available at the point of care with scalable capacities will facilitate the rapid and accurate diagnosis and monitoring of SARS-CoV-2 infections and greatly assist in the control of this outbreak. | 2020-04-04 |
| 32246819 | Thus, suspected cases need to be closely monitored, and epidemiological history and clinical laboratory examination should also be considered during diagnosis. | 2020-04-09 |
| 32246822 | Nucleic acid testing (NAT) has played an important role in patient diagnosis and management of COVID-19. | 2020-04-04 |
| 32246838 | We had a dedicated task force that identified a response plan, which included: (1) establishment of dedicated, cohorted intensive care unit(s) (ICU) for COVID-19-positive patients; (2) design of appropriate procedures for pre-triage, diagnosis and isolation of suspected and confirmed cases; and (3) training of all staff to work in the dedicated ICU in personal protective equipment use and patient management. | 2020-04-04 |
| 32249943 | In summary, knowledge of these differences between children and adults will not only be helpful for the clinical diagnosis of 2019 novel coronavirus disease (COVID-19), but also for a future discussion on age-specific coronavirus infection. | 2020-04-06 |
| 32249944 | The diagnosis was performed by the virology team under direction of Maria R. | 2020-04-06 |
| 32250170 | Plant biotechnology offers potential solutions to this pandemic through the development of low-cost vaccines and antibodies useful for therapy, prophylaxis, and diagnosis. | 2020-04-16 |
| 32250958 | Using a third-party statistics tool, we anonymously monitored user activity as well as content utilization patterns since the diagnosis of the first case of SARS-CoV-2 in Switzerland on February 25, 2020. | 2020-04-16 |
| 32251668 | We collected data from the cohort of patients with COVID-19 in Hong Kong (n=59; diagnosis from February 2 through Feb 29, 2020), and searched PubMed, Embase, Cochrane and three Chinese databases through March 11, 2020 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. | 2020-04-06 |
| 32251790 | To prevent further outbreak of COVID-19, this article discusses the current understanding of COVID-19 and compares with the outbreak of SARS-CoV-2 in 2003 of Hong Kong from the causes, transmission, symptoms, diagnosis, treatments and preventions to study for an applicable measurement to control COVID-19. | 2020-04-06 |
| 32251798 | To investigate the diagnostic value of serological test and dynamitic variance of serum antibody in coronavirus disease 2019 (COVID-19). […] Viral serological test is an effective diagnostic means for SARS-CoV-2 infection. | 2020-04-06 |
| 32253371 | To provide insights on this issue, a 25-items online Survey was sent to all Italian residents one month after the first case of COVID-19 in Italy, to evaluate their routine involvement in “clinical” (on-call duty, outpatient visits, diagnostic procedures) and “surgical” (endoscopic, open and minimally invasive surgery) training activities before and during the COVID-19 period. | 2020-04-07 |
| 32255413 | For these regions, healthcare delivery has been disrupted and compromised by critical resource constraints in diagnostic testing, hospital beds, ventilators, and healthcare workers who have fallen ill to the virus exacerbated by shortages of personal protective equipment. […] Thoracic imaging with chest radiography (CXR) and computed tomography (CT) are key tools for pulmonary disease diagnosis and management, but their role in the management of COVID-19 has not been considered within the multivariable context of the severity of respiratory disease, pre-test probability, risk factors for disease progression, and critical resource constraints. | 2020-04-08 |
| 32257173 | From the research objectives for SARS-CoV and MERS-CoV, ten themes in the literature were identified: Clinical characterisation, prognosis, diagnosis, clinical management, viral pathogenesis, epidemiological characterisation, infection prevention and control/transmission, susceptibility, psychosocial, and aetiology. […] For COVID19, some information on clinical presentation, diagnostic testing, and aetiology is available but many clinical research gaps have yet to be filled. | 2020-04-15 |
| 32259123 | Where needed, clients are referred to 16-hour treatment clinics, which are specifically set up for the diagnosis and treatment of the disease, to the hospitals, or will be treated at home. | 2020-04-09 |
| 32259130 | Accordingly, our narrative review appraised epidemiological and clinical aspects of the disease including genetic diversity of coronavirus genus, mode of transmission, incubation period, infectivity, pathogenicity, virulence, immunogenicity, diagnosis, surveillance, clinical case management and also successful measures for preventing its spread in some communities. | 2020-04-09 |
| 32259132 | This diagnostic accuracy study was conducted on suspected COVID-19 patients, who presented to Behpooyan Clinic Medical center in Tehran (Iran) from 22 February to 14 March, 2020. | 2020-04-09 |
| 32259403 | Children who have a familial clustering or have a family member with a definite diagnosis should be reported to ensure a timely diagnosis. | 2020-04-07 |
| 32259546 | To describe an outbreak investigation of a patient with COVID-19 who was nursed in an open cubicle of a general ward before the diagnosis was made. | 2020-04-09 |
| 32259829 | Highly sensitive and specific diagnostic assays are key to case identification, contact tracing, identification of the animal source, and implementation of control measures. | 2020-04-07 |
| 32259853 | Diagnosis relies on clinical presentation, exposure history, PCR using specimens from the respiratory tract together with computed tomography (CT) imaging. | 2020-04-07 |
| 32260436 | ECG-derived respiration techniques were used in conjunction with a novel, phonocardiogram-derived respiration approach to extract respiratory parameters. | 2020-04-10 |
| 32260471 | There have been tremendous advances in in vitro diagnostic (IVD) assays for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] A wide range of serology immunoassays (IAs) have also been developed that complement the molecular assays for the diagnosis of COVID-19. […] However, the performance of IVD assays needs to be critically evaluated before they are employed for the clinical diagnosis of COVID-19. | 2020-04-08 |
| 32265088 | A proof of concept (PoC) and prototype are presented, demonstrating a reusable custom-made three-dimensionally (3D) printed face mask based on materials and techniques (3D imaging and 3D printing) with global availability. | 2020-04-16 |
| 32265202 | However, conjunctival sampling might not be useful for early diagnosis because the virus may not appear initially in the conjunctiva. | 2020-04-08 |
| 32265220 | Three models were identified for predicting hospital admission from pneumonia and other events (as proxy outcomes for covid-19 pneumonia) in the general population; 18 diagnostic models for detecting covid-19 infection (13 were machine learning based on computed tomography scans); and 10 prognostic models for predicting mortality risk, progression to severe disease, or length of hospital stay. […] C index estimates ranged from 0.73 to 0.81 in prediction models for the general population (reported for all three models), from 0.81 to more than 0.99 in diagnostic models (reported for 13 of the 18 models), and from 0.85 to 0.98 in prognostic models (reported for six of the 10 models). […] Finally, studies should adhere to the TRIPOD (transparent reporting of a multivariable prediction model for individual prognosis or diagnosis) reporting guideline. | 2020-04-10 |
| 32266184 | One had rashes at birth but was discharged without parental consent for a diagnostic test. | 2020-04-10 |
| 32266524 | The definite diagnosis of corona virus disease 2019 (COVID-19) is based on the viral isolation or positive result of polymerase chain reaction (PCR) from sputum, or nasal swab, or throat swab. | 2020-04-08 |
| 32267072 | Management depends on the recognized diagnosis. | 2020-04-09 |
| 32267109 | The diagnosis is most often based on the detection of the viral genome in the nasopharynx by molecular biology methods. […] Le diagnostic repose, le plus souvent, sur la détection du génome viral au niveau du nasopharynx par des méthodes de biologie moléculaire. | 2020-04-09 |
| 32267209 | Radiology departments play a critical role in policy and guideline development both for the department and for the institutions, specifically in planning diagnostic screening, triage, and management of patients. | 2020-04-08 |
| 32267220 | Although molecular diagnostic tests were rapidly developed, serologic assays are still lacking, yet urgently needed. […] Overall, the validated assays described can be instrumental for detection of SARS-CoV-2-specific antibodies for diagnostic, seroepidemiologic, and vaccine evaluation studies. | 2020-04-08 |
| 32268019 | High-flow nasal cannula (HFNC) has been utilized widely due to its superiority over other non-invasive respiratory support techniques. | 2020-04-10 |
| 32268454 | After admission, 6 patients were given routine treatment, the medical staffs paid attention to the protection and screened COVID-19 according to the diagnosis and treatment plan of COVID-19. | 2020-04-08 |
| 32269893 | Furthermore, the limitations and statistical strength of the diagnostic tools currently in clinical practice are evaluated. | 2020-04-11 |
| 32270477 | In the context of the COVID-19 pandemic, patients need to be evaluated within 2-4 weeks in the following cases: cytology result of “squamous cell carcinoma,” “atypical glandular cells, favor neoplastic,” “endocervical adenocarcinoma in situ,” or “adenocarcinoma”; histopathological diagnosis of suspected invasion from cervical/vaginal biopsy, or invasive disease after a cervical excision procedure, vaginal excision, or vulvar biopsy/excision; sudden onset of strongly suggestive symptoms for malignancy. | 2020-04-09 |
| 32270581 | For any care or intervention in the upper aerodigestive tract region, irrespective of the setting and a confirmed diagnosis (eg, rhinoscopy or flexible laryngoscopy in the outpatient setting and tracheostomy or rigid endoscopy under anesthesia), it is strongly recommended that all health care personnel wear personal protective equipment such as N95, gown, cap, eye protection, and gloves. | 2020-04-15 |
| 32270938 | The Covid-19 pandemic imposes new diagnostic strategies in order to optimize the medical care of our patients. | 2020-04-13 |
| 32271208 | Diagnostic Level IV. | 2020-04-09 |
| 32271596 | They were referred to the intended centers for COVID-19 diagnosis and management of Shiraz University of Medical Sciences in southern Iran. | 2020-04-14 |
| 32271599 | Therefore, cancer patients require higher level measures for preventing and treating infectious diseases. furthermore, cancer patients may bear additional risk due to the restriction of access to the routine diagnostic and therapeutic services during such epidemic. […] This article provides the recommendations and possible actions that should be considered by patients, their caregivers and families, physician, nurses, managers and staff of medical centers involved in cancer diagnosis and treatment. […] We pursued two major goals in our recommendations: first, limiting the exposure of cancer patients to medical environments and second, modifying the treatment modalities in a manner that reduces the probability of myelosuppression such as delaying elective diagnostic and therapeutic services, shortening the treatment course, or prolonging the interval between treatment courses. | 2020-04-14 |
| 32271601 | Recently, accurate RNA detection has been decisive for the diagnosis of COVID-19. | 2020-04-14 |
| 32271602 | The number of infected people is rapidly increasing, while the diagnostic method of COVID-19 is only by nucleic acid testing. […] To explain the epidemiological characteristics, clinical features, imaging manifestations and to judge diagnostic value of COVID-19 by analyzing the clinical data of COVID-19 suspected and confirmed patients in a non-outbreak, Shanghai, China. | 2020-04-14 |
| 32271724 | At the time the investigation began, testing guidance recommended focusing on persons with clinical findings of lower respiratory illness and travel to an affected area or an epidemiologic link to a laboratory-confirmed COVID-19 case, or on persons hospitalized for severe respiratory disease and no alternative diagnosis (1). | 2020-04-10 |
| 32272080 | Streamlining of workflows for rapid diagnosis and isolation, clinical management, and infection prevention will matter not only to patients with COVID-19, but also to health-care workers and other patients who are at risk from nosocomial transmission. | 2020-04-09 |
| 32272262 | Clinical performances of patients with COVID-19, mostly with epidemiologic history and typical symptoms, were critical valuable in the diagnosis of the COVID-19. | 2020-04-11 |
| 32272857 | In light of the current novel coronavirus (COVID-19) pandemic, as well as other viral outbreaks in the 21st century, there is a dire need for new diagnostic and therapeutic strategies to combat infectious diseases worldwide. | 2020-04-15 |
| 32273490 | Diagnosis is by Reverse transcriptase-Polymerase chain reaction (RT-PCR) testing of upper or lower respiratory tract secretions. | 2020-04-10 |
| 32275128 | To analyze the roles of multidisciplinary team (MDT) in the diagnosis and treatment of suspected cases of corona virus disease 2019 (COVID-19). […] The efficiency of diagnosis and treatment for suspected COVID-19 patients can be improved under MDT mode, particularly for complicated and refractory cases. | 2020-04-13 |
| 32275257 | This review summarizes current strategies on the diagnosis. […] The SARS-CoV-2 causes changes in blood cells and factors and makes lung abnormalities in patients, which can be detected by serological, molecular, and radiological techniques by detecting these changes and injuries. | 2020-04-15 |
| 32275288 | The study included 214 consecutive hospitalized patients with laboratory-confirmed diagnosis of severe acute respiratory syndrome coronavirus 2 infection. […] During the epidemic period of COVID-19, when seeing patients with neurologic manifestations, clinicians should suspect severe acute respiratory syndrome coronavirus 2 infection as a differential diagnosis to avoid delayed diagnosis or misdiagnosis and lose the chance to treat and prevent further transmission. | 2020-04-14 |
| 32275452 | Patients were divided into four groups according to age and into three groups (moderate, severe, and critical group) according to the fifth version of the guidelines issued by the National Health Commission of China on Diagnosis and Treatment of COVID-19. | 2020-04-10 |
| 32275742 | The diagnosis of coronavirus disease 2019 (COVID-19) was confirmed by real-time reverse transcriptase polymerase chain reaction testing on postmortem swabs. | 2020-04-10 |
| 32275766 | Compared to other monitoring modalities, such as auscultation or radiographic imaging, we argue lung ultrasound has high diagnostic accuracy, is ergonomically favourable and has fewer infection control implications. | 2020-04-10 |
| 32275784 | Telemedicine, defined as the delivery of health care services at a distance using electronic means for diagnosis and treatment, holds tremendous promise to increase access to broadly specialty care. | 2020-04-10 |
| 32275978 | For these regions, healthcare delivery has been disrupted and compromised by critical resource constraints in diagnostic testing, hospital beds, ventilators, and healthcare workers who have fallen ill to the virus exacerbated by shortages of personal protective equipment. […] Thoracic imaging with chest radiography (CXR) and computed tomography (CT) are key tools for pulmonary disease diagnosis and management, but their role in the management of COVID-19 has not been considered within the multivariable context of the severity of respiratory disease, pre-test probability, risk factors for disease progression, and critical resource constraints. | 2020-04-16 |
| 32276051 | Diagnosis of COVID-19 is currently performed by RT-qPCR methods, but the capacity of RT-qPCR methods is limited by its requirement of high-level facilities and instruments. | 2020-04-13 |
| 32276116 | To describe the availability of this method in clinical diagnosis, we collected 130 specimens from patients with clinically suspected SARS-CoV-2 infection. | 2020-04-13 |
| 32276755 | Chest radiography and chest CT are frequently used to support the diagnosis of COVID-19 infection. | 2020-04-14 |
| 32276930 | Amid concerns over the spread of COVID-19, oncology practices have “gone virtual,” with video appointments scheduled for any service that does not require diagnostic testing or treatment. | 2020-04-11 |
| 32277022 | Laboratories are currently witnessing extraordinary demand globally for sampling devices, reagents, consumables, and diagnostic instruments needed for timely diagnosis of SARS-CoV-2 infection. […] To meet diagnostic needs as the pandemic grows, the US Food and Drug Administration (FDA) recently granted several commercial SARS-CoV-2 tests Emergency Use Authorization (EUA), but manufacturer-independent evaluation data are scarce. […] Immediate prospective head-to-head comparative evaluation followed on 502 samples, and the diagnostic approaches showed overall percent agreement of 99.6% and a kappa value of 0.98. […] Under the extraordinary circumstances that laboratories are facing worldwide, a safe diagnostic platform switch is feasible in only 48 hours and in the midst of the COVID-19 pandemic if carefully planned and executed. | 2020-04-11 |
| 32277387 | It is urgent to set up guidelines for the prevention, diagnosis, and treatment of COVID-19 in liver transplant recipients. | 2020-04-11 |
| 32277408 | The patient conformed to the diagnostic criteria of the Chinese expert consensus statement for fulminant myocarditis. | 2020-04-11 |
| 32277490 | For patients, concerns about Severe Acute Respiratory Syndrome-Corona Virus 2 (SARS-CoV2) will add to the anxiety caused by the diagnosis of a serious fetal anomaly, and for fetal medicine teams the situation gets more complex. | 2020-04-11 |
| 32277763 | The COVID-19 pandemic has necessitated cancelation of elective or non-urgent contact with the healthcare system, including non-urgent nerve conduction studies and electromyography (electrodiagnostic [EDX] studies). | 2020-04-11 |
| 32277845 | There are limitations associated with sensitivity and specificity of diagnostic tests used and classification of patients based on test results has also been questioned. | 2020-04-11 |
| 32277967 | Monitoring dynamic changes of SAA, combined with CT imaging could be valuable in diagnosis and treatment of COVID-19. | 2020-04-14 |
| 32278065 | We searched on PubMed, EMBASE, and Web of Science up to March 2020 to identify studies documenting diarrhea and mechansism of intestinal inflammation in patients with confirmed diagnosis of SARS-CoV-2 infection. […] Increasing evidence indicates possible fecal oral transmission, indicating the need for a rapid and effective modification of the screening and diagnostic algorithms. | 2020-04-13 |
| 32278764 | We searched for articles in PubMed and Google Scholar databases till 02 April 2020, with the following keywords: “SARS-CoV-2”, “COVID-19”, “infection”, “pathogenesis”, “incubation period”, “transmission”, “clinical features”, “diagnosis”, “treatment”, “diabetes”, with interposition of the Boolean operator “AND”. | 2020-04-16 |
| 32279934 | The latter leads to an acceptable choice of materials and techniques for personal protection and prevention of cross-contamination to other patients and staff. […] The authors have presented a protocolized approach that uses diagnostic criteria to clearly define benchmarks from the medical history along with clinical symptoms and laboratory tests. […] Patients can then be rapidly assigned into 1 of 3 risk categories that direct the choice of protective materials and/or techniques. | 2020-04-16 |
| 32280076 | There were some typical CT features for diagnosis of COVID-19 pneumonia. | 2020-04-13 |
| 32281327 | Taking full advantage of the clinical experience of traditional Chinese medicine(TCM) in preventing and controlling major epidemics such as SARS, it is an important mission for TCM to propose effective formula with immediate response and solid evidence by using modern biomedical knowledge and techniques(molecular docking assisted TCM formulation for short). | 2020-04-14 |
| 32281328 | By combining the diagnosis and treatment scheme of Hunan province’s and angiotensin converting enzyme 2(ACE2) inhibitors screening from literature, present study also discussed the rational application of candidate herbs to this epidemic situation. | 2020-04-14 |
| 32281329 | In the end, we obtained the potential active prescriptions on "cytokine storm" according to the potential herbs in the "National novel coronavirus pneumonia diagnosis and treatment plan(trial version sixth)". | 2020-04-14 |
| 32281331 | To investigate the regularity of prescription and clinical syndromes by analyzing the diagnosis and treatment protocols of traditional Chinese medicine(TCM) for coronavirus disease 2019(COVID-19), so as to provide references for syndrome differentiation and relevant researches. […] The diagnosis and treatment protocols of COVID-19 published by national and regional health authorities were searched, and information was extracted in regard to disease stages, type of syndromes, and prescriptions, etc. […] A total of 26 diagnosis and treatment protocols of TCM for COVID-19 were retrieved after screening(including 1 national scheme and 25 regional ones), among which 16 contained aspects of both prevention and treatment, 7 only involved treatment contents and 3 were prevention schemes. […] There were many diagnosis and treatment protocols for COVID-19 have been published, which generally followed the national edition, through with certain personalities in different regional protocols. […] Along with the deepening recognition of COVID-19, the diagnosis and treatment protocols are still need further concretization and standardization. | 2020-04-14 |
| 32281333 | This study collected prevention and treatment approaches of traditional Chinese medicine for COVID-19 released from the National Health Committee of China, 7 provinces and municipal health committees, the Chinese Medicine Administration and Handbook of Traditional Chinese Medicine Diagnosis and Treatment of COVID-19 between January 1 and February 18, 2020, and prescriptions prepared by 3 masters of Chinese medicine and 4 well-known Chinese medicine experts. | 2020-04-14 |
| 32281335 | Chinese patent medicines and prescriptions in medical observation and clinical treatment were recommended in the "pneumonia diagnosis and treatment plan for new coronavirus infection"(trial version fifth) of the National Health Commission of the People’s Republic of China. | 2020-04-14 |
| 32281391 | We recommend to set up an isolation zone for handling patients who do not meet the diagnostic criteria of COVID-19 but are not completely cleared of the possibility of infection. | 2020-04-13 |
| 32281667 | " 1 which report the clinical features, diagnosis and treatment of the novel Coronavirus Disease 2019 (COVID-19). | 2020-04-13 |
| 32281668 | The present study aimed to analyze the characteristics of severe COVID-19 and identify biomarkers for differential diagnosis and prognosis prediction. | 2020-04-13 |
| 32281757 | However, as Covid-19 is an emerging disease, more work is needed to improve prevention, diagnosis and treatment strategies. […] It is essential to avoid nosocomial spread; in order to control and reduce the rate of infections it is necessary to strengthen the management of medical and nursing personnel through the early diagnosis, isolation and treatment of patients undergoing dialysis treatment. | 2020-04-16 |
| 32281785 | Reliable laboratory diagnosis of the disease has been one of the foremost priorities for promoting public health interventions. […] The routinely used reverse transcription polymerase chain reaction (RT-PCR) is currently the reference method for COVID-19 diagnosis. […] In this work, a dual-functional plasmonic biosensor combining the plasmonic photothermal (PPT) effect and localized surface plasmon resonance (LSPR) sensing transduction provides an alternative and promising solution for the clinical COVID-19 diagnosis. […] This study gains insight into the thermoplasmonic enhancement and its applicability in the nucleic acid tests and viral disease diagnosis. | 2020-04-16 |
| 32282372 | Here he considers the implications of exemplary innovations-virtual care, hospital at home, advances in diagnosis and therapy, virtual learning, and virtual clinical learning-for regulators, academic medical centers, faculty, and students. | 2020-04-13 |
| 32282404 | It is critical for Nuclear Medicine physicians to develop diagnostic skills for timely recognition of typical findings of C-19AP on a localizing CT. | 2020-04-13 |
| 32282863 | In this minireview, we provide a brief introduction of the general features of SARS-CoV-2 and discuss current knowledge of molecular immune pathogenesis, diagnosis and treatment of COVID-19 on the base of the present understanding of SARS-CoV and MERS-CoV infections, which may be helpful in offering novel insights and potential therapeutic targets for combating the SARS-CoV-2 infection. | 2020-04-16 |
| 32282894 | Diagnostic testing to identify persons infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) infection is central to control the global pandemic of COVID-19 that began in late 2019. […] In a few countries, the use of diagnostic testing on a massive scale has been a cornerstone of successful containment strategies. […] Although excellent tools exist for the diagnosis of symptomatic patients in well-equipped laboratories, important gaps remain in screening asymptomatic persons in the incubation phase, as well as in the accurate determination of live viral shedding during convalescence to inform decisions to end isolation. […] Here, the authors review the current array of tests for SARS-CoV-2, highlight gaps in current diagnostic capacity, and propose potential solutions. | 2020-04-13 |
| 32283006 | Attempts at slowing the pandemic at this stage depend on the number and quality of diagnostic tests performed. | 2020-04-13 |
| 32283141 | The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time RT-PCR. | 2020-04-13 |
| 32283185 | The two cohorts (cryopreserved versus fresh) were similar in patient age, KPS, diagnosis, DRI, HCT-comorbidity index, donor/graft source, and conditioning intensity. | 2020-04-13 |
| 32283268 | With the high transmissibility of the virus, there has been an increasing concern for the development of techniques to perform surgical intervention while mitigating the risk for infecting hospital staff. | 2020-04-15 |
| 32283498 | Ample data is available to suggest the differences in etiology, transmission cycle, diagnosis, genetics, hosts, reproductive rates, clinical features, laboratory diagnosis and radiological features between SARS-CoV-1, MERS-CoV and SARS-CoV-2. | 2020-04-15 |
| 32285293 | This article will summarize the role of ACE2 in multiple organ damage caused by COVID-19 and SARS-CoV, targeted blocking drugs against ACE2, and drugs that inhibit inflammation in order to provide the basis for subsequent related research, diagnosis and treatment, and drug development. | 2020-04-14 |
| 32285338 | Among surgeons worldwide, a concern with the use of minimally invasive techniques has been raised due to a proposed risk of viral transmission of the coronavirus disease of 2019 (COVID-19) with the creation of pneumoperitoneum. | 2020-04-14 |
| 32285862 | The publication of full-genomes of the newly identified coronavirus (initially called 2019-nCoV, now called SARS-CoV2) in public and private databases, of standardized diagnostic protocols and of the clinical-epidemiological information generated will allow addressing the Public Health Emergency of International Concern (PHEIC), declared on January 30 by the WHO. | 2020-04-16 |
| 32285949 | This report provides reference for the diagnosis and treatment of HIV-infected patients with COVID-19. | 2020-04-14 |
| 32286155 | Confirmative diagnosis of SARS-CoV-2 infections has been challenged due to unsatisfactory positive rate of molecular assays. […] Our results emphasized the significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections, especially for COVID-19 close contacts screening. | 2020-04-14 |
| 32286216 | This is a review of diagnostic imaging findings in coronavirus disease-2019 (COVID-19). […] Initially the CT can be normal, and the diagnostic performance for COVID-19 is not optimal. | 2020-04-15 |
| 32286242 | A viral nucleic acid test is used for the diagnosis of COVID-19, and some hematological indicators have been used in the auxiliary diagnosis and identification of the severity of COVID-19. | 2020-04-14 |
| 32286916 | Until preoperative diagnostic testing becomes standardized and readily available, elective cases should be deferred and emergent/urgent cases should be treated as high risk for COVID-19 exposure. | 2020-04-14 |
| 32287040 | The HHS was designed for the collection, integration, standardization, and analysis of COVID-19-related data from multiple sources, which includes a case reporting system, diagnostic labs, electronic medical records, and social media on mobile devices. | 2020-04-14 |
| 32289466 | This is a cross-sectional study of patients who received a COVID-19 diagnosis between December 30, 2019 and February 7, 2020 at Tongji Hospital. […] A total of 102 patients (48 Male [47%] and 54 Female [53%]) with clinical symptoms, Rt, and chest Computed Tomography (CT) abnormalities were identified with a clinical diagnosis of COVID-19. […] Of a total of 102 patients identified, 72 patients (36 men [50%] and 36 women [50%]; mean [SD] age, 58.68 [14.81] years) were confirmed to have COVID-19 by laboratory diagnosis with a SARS-CoV-2 RT-PCR assay. […] To lower the SARS-CoV-2 nosocomial infection, all health care professionals should wear protective goggles.The inefficient diagnostic method and the sampling time lag may contribute to the lower positive rate of conjunctival swab samples of SARS-CoV-2. | 2020-04-14 |
| 32290643 | To summarize the administration model of a COVID-19 designated hospital transformed from a community hospital to improve the emergency capacity of community hospitals and the efficiency of diagnosis and treatment of medical staff in the COVID-19 pandemic. […] Its diagnosis and treatment model has completed the treatment of COVID- 19 patients successfully. | 2020-04-15 |
| 32291080 | As this is a respiratory infection, chest radiography and computed tomography (CT) are important imaging techniques in the work-up of this disease. […] We describe the response of radiology departments in Singapore to this pandemic, in terms of diagnosis, re-configuration of the department, re-organisation and segregation of staff, infection control, managerial, and leadership issues. | 2020-04-15 |
| 32291197 | Computed tomography (CT) can be used as an important complement for the diagnosis of COVID-19 pneumonia in the current epidemic context. […] In this review, we present the typical CT features of COVID-19 pneumonia and discuss the main differential diagnosis. | 2020-04-15 |
| 32291207 | We enrolled patients with confirmed diagnosis of COVID-19 retrospectively and collected heart-related clinical data, mainly including cardiac imaging findings, laboratory results and clinical outcomes. | 2020-04-15 |
| 32291374 | One of the challenges in managing COVID-19 is the identification of a swift, accessible, and reliable diagnostic modality that could serve as an alternative to a reverse-transcriptase polymerase chain reaction (RT-PCR). […] As of the writing of this paper, RT-PCR is still the recommended tool in diagnosing COVID-19, but the notion of a more prompt and accurate diagnostic tool is a possibility worth looking into. […] The objective of this case study is to investigate the importance and utility of chest computed tomography (CT) in the diagnosis of COVID-19, as increasing pieces of evidence suggest that chest CT could prove useful in the clinical pathway in diagnosing COVID-19. | 2020-04-16 |
| 32291501 | As the majority of patients infected with COVID-19 had chest CT abnormality, chest CT has become an important tool for early diagnosis of COVID-19 and monitoring disease progression. […] This review is mainly about the differences in clinical symptom spectrum, diagnosis of COVID-19, and CT imaging findings between adults and children, while highlighting the value of radiology in prevention and control of COVID-19 in pediatric patients. | 2020-04-15 |
| 32291542 | In this review, we summarized the epidemiological characteristics, clinical features, diagnosis, treatment, and prognosis of COVID-19. | 2020-04-15 |
| 32292205 | The COVID-19 epidemic should be considered a global threat and the steps for control include early diagnosis and treatment, as well as isolation. | 2020-04-15 |
| 32292213 | Molecular diagnostic methods have been established in a very short time and a number of clinical studies on the effectiveness of different antiviral drugs are ongoing. | 2020-04-15 |
| 32292529 | As the epicentre of the initial outbreak, China has been updating the National COVID-19 Diagnostic and Treatment Guideline with up-to-date information about the disease. | 2020-04-15 |
| 32292623 | It is important to establish a quick standard diagnostic test for the detection of the infectious disease (COVID-19) to prevent subsequent secondary spread. […] Polymerase chain reaction (PCR) is regarded as a gold standard test for the molecular diagnosis of viral and bacterial infections with high sensitivity and specificity. […] It is anticipated that this will assist researchers and clinicians in developing better techniques for timely and effective detection of coronavirus infection. | 2020-04-15 |
| 32292637 | Based on refined management theory, we professionally developed the standards for prevention and control of COVID-19 in non-isolated areas, systematically implemented various prevention and control measures, performed gridding audit, effectively communicated among teams and between doctors and patients assisted by information techniques, and reported results for quality improvement. | 2020-04-15 |
| 32292697 | All patients received oral HGF therapy for six months when they were confirmed the diagnosis of steroid-associated ONFH. | 2020-04-15 |
| 32292802 | We have also provided information about the classification, genome, proteins, clinical presentation of COVID-19, type of clinical specimens to be collected and diagnostic methods adopted to identify the respiratory illness. | 2020-04-15 |
| 32292826 | Since the coronavirus disease 2019 (COVID-19) outbreak was identified in December 2019 in Wuhan, China, a strong response from the research community has been observed with the proliferation of independent clinical trials assessing diagnostic methods, therapeutic and prophylactic strategies. | 2020-04-15 |
| 32292880 | The appearance of pneumonia is one of the major clues for the diagnosis, progress and therapeutic evaluation. | 2020-04-15 |
| 32292902 | An overt diagnosis of pneumonia was made in 91.8% and the most common symptoms were fever (82.6%), cough (57.1%) and dyspnea (27.0%). | 2020-04-15 |
| 32292904 | The diagnosis, infection control, and treatment of COVID-19 in hemodialysis patients are discussed in this report, and we conclude with recommendations for how a dialysis facility can respond to COVID-19 based on our experiences. | 2020-04-15 |
| 32293168 | Because no specific drugs or vaccines for COVID-19 are yet available, early diagnosis and management are crucial for containing the outbreak. […] Thus, we have successfully fabricated a promising FET biosensor for SARS-CoV-2; our device is a highly sensitive immunological diagnostic method for COVID-19 that requires no sample pretreatment or labeling. | 2020-04-15 |
| 32293743 | In general, respiratory viral co-infections are recognized more commonly today with the use of respiratory multiplex molecular diagnostic panels. […] A high degree of suspicion in this rapidly evolving outbreak is required in order to make the diagnosis. | 2020-04-15 |
| 32294077 | The goal of this column is to inform mental health care professionals about the evolving way the diagnosis of Coronavirus Disease 2019 (COVID-19) is being made, with emphasis on tests to assist in making the diagnosis and to determine the presence of antibodies to the virus. | 2020-04-15 |
| 32294796 | This study was conducted to explore the clinical value of noninvasive assessment of bedside ultrasound in the diagnosis of lung lesions of Coronavirus Disease-19. […] The ultrasound scores to evaluate mild, moderate and severe lung lesions exhibited sensitivity of 68.8 % (11/16), 77.8 % (7/9), 100.0 % (2/2), specificity of 85.7 % (12/14), 76.2 % (16/21), 92.9 % (26/28), and diagnostic accuracy of 76.7 % (23/30), 76.7 % (23/30), 93.3 % (28/30), respectively. […] Though the diagnostic efficacy of bedside ultrasound is relatively low for mild to moderate patients, it is high for severe patients. | 2020-04-15 |
| 32294816 | The results showed that the positive rate of bronchoalveolar lavage for detection of new coronavirus nucleic acid was high, and bronchoalveolar lavage for suspected or confirmed new coronavirus pneumonia patients with negative detection of nucleic acid in pharynx swabs but still residual lung lesions was helpful for early diagnosis, treatment and prognosis. | 2020-04-17 |
| 32294858 | Objective: To explore the CT imaging features of the 2019 novel coronavirus (2019-nCoV) infection in order to summarize the imaging characteristics of the disease and improve the ability of imaging diagnosis and early diagnosis of the disease. Methods: From January 13, 2020 to January 31, 2020, a total of 33 patients with 2019-nCoV infection diagnosed and treated by Suzhou Fifth People’s Hospital were analyzed retrospectively, including 20 males and 13 females, with an average age of (50±12) years, ranging from 20 to 70 years old. […] CT images can indicate the diagnosis of COVID-19 and provide important basis for early detection and disease monitoring. 目的： 探讨新型冠状病毒（2019-nCoV）感染患者的肺部CT影像表现，总结其影像特征，提高对该病肺部影像诊断能力。 | 2020-04-17 |
| 32295188 | We performed a narrative review to describe existing literature with regard to Corona Virus Disease 2019 (COVID-19) epidemiology, pathophysiology, diagnosis, management and future perspective. […] In particular, we focus on public health impact, pathophysiology and clinical manifestations, diagnosis, case management, emergency response and preparedness. | 2020-04-21 |
| 32295322 | Objective: To analyze the epidemiological characteristics and clinical features of the patients with 2019-nCoV infection in Nanyang City, so as to provide evidence for clinical diagnosis and treatment. Methods: The epidemiology, clinical symptoms, atory and radiologic data of 150 patients with 2019-nCoV infection admitted to the designated hospitals in Nanyang City from January 24,2020 to February 16, 2020 were retrospectively analyzed. Results: The 150 patients with 2019 nCov infection consisted of 67 men and 83 women, and the median age was 45±16 years; 69 of them were the first generation case,60 of them were the second generation case, 6 of them were the third generation case,the median incubation period of the first generation case was 5.4±2.2 days, and the second generation case was 6.7±3.1 days, and the first-generation cases are the majority in severe patients (69%) . […] After active treatment, 45% of patients were discharged according to discharge standards. 33% of sever and critically ill patients were discharged, 49% of them were degraded hospitalization.The average length of hospitalization was 12±4 days. Conclusion: A history of epidemiological exposure, fever, chest CT with signs of pneumonia, normal or decreased WBC, and lymphocytopenia, eosinophilia are the clinical basis for the diagnosis of this disease, and most of the sever patients were the first generation cases. | 2020-04-16 |
| 32295323 | Based on the characteristics of sleep-disordered breathing, this consensus elaborates on the recommendations from the following four aspects that include patient and medical staff education, optimization of diagnostic and treatment protocols, sterilization of medical devices and the environment, and control of hospital-acquired infection. | 2020-04-16 |
| 32295324 | Conjunctival swab novel coronavirus nucleic acid test was performed on patients with clinical manifestation of conjunctivitis. Results: Only 3 of the 81 patients (3.70%) complained of eye discomfort, which appeared on the day 16.67±9.29 after the diagnosis of coronavirus disease-19. […] There was no evidence to support the diagnosis of novel coronavirus related conjunctivitis. | 2020-04-16 |
| 32296473 | An abdominal CT scan ruled out a diagnosis of appendicitis and a chest CT scan yielded a diagnosis of SARS-CoV-2 infection. | 2020-05-07 |
| 32296826 | However, as the diagnosis criteria changed, a sudden increase (slope=5530) was observed on 12th Feb., which sharply decreased afterward (slope=-4898). | 2020-04-30 |
| 32296837 | We analyzed routine diagnostic data for >70,000 episodes of respiratory illness tested molecularly for multiple respiratory viruses between 2005 and 2017. […] These findings highlight the importance of considering cocirculating viruses in the differential diagnosis of COVID-19. | 2020-04-30 |
| 32296940 | Imaging exams have been a main clinical diagnostic criteria for the 2019 novel coronavirus disease (COVID-19) in China. […] Imaging features of multiple patchy areas of ground glass opacity and consolidation predominately in the periphery of the lungs are characteristic manifestations on chest CT and extremely helpful in the early detection and diagnosis of this disease, which aids prompt diagnosis and the eventual control of this emerging global health emergency. […] • Imaging examination has become the indispensable means not only in the early detection and diagnosis but also in monitoring the clinical course, evaluating the disease severity, and may be presented as an important warning signal preceding the negative RT-PCR test results. | 2020-04-30 |
| 32297723 | Hence, the standard infection control techniques and preventive steps for healthy individuals and supportive care for the confirmed cases is the best available strategy to deal with current viral outbreak. . | 2020-04-20 |
| 32297868 | We provide several use cases for infection control, home-based diagnosis and screening, empowerment through information, public health surveillance and epidemiology, and leveraging crowd-sourced data. | 2020-04-21 |
| 32297981 | At present, it mainly relies on Real-time RT-PCR to detect SARS-CoV-2 virus nucleic acid collected from the clinical specimens of patients as the standard for diagnosis, discontinuation of quarantine and discharge.1,2 This article is protected by copyright. | 2020-04-27 |
| 32298029 | Patients who need to be hospitalized for cancer treatment were protected from potential SARS-CoV-2 infection by creating a dedicated diagnostic and therapeutic internal pathway for cancer treatment. | 2020-04-27 |
| 32298139 | Context. Point-of-care testing (POCT), diagnostic testing at or near the site of patient care, is inherently spatial , that is, performed at points of need, and also intrinsically temporal , because it produces fast actionable results. […] The COVID-19 pandemic demonstrates unequivocally that governments must support POCT and multidisciplinary healthcare personnel must learn its principles, then adopt POC geospatial strategies, so that onsite diagnostic testing can ramp up to meet needs in times of crisis. | 2020-04-16 |
| 32298149 | The purpose of this article is to critically review some of the most frequently cited studies on the use of CT for detecting COVID-19. CONCLUSION. To date, the radiology literature on COVID-19 has consisted of limited retrospective studies that do not substantiate the use of CT as a diagnostic test for COVID-19. | 2020-04-16 |
| 32298250 | Geographic differences in numbers of COVID-19 cases and deaths, cumulative incidence, and changes in incidence likely reflect a combination of jurisdiction-specific epidemiologic and population-level factors, including 1) the timing of COVID-19 introductions; 2) population density; 3) age distribution and prevalence of underlying medical conditions among COVID-19 patients (1-3); 4) the timing and extent of community mitigation measures; 5) diagnostic testing capacity; and 6) public health reporting practices. | 2020-04-17 |
| 32298676 | The role of saliva in COVID-19 diagnosis could not be limited to a qualitative detection of the virus, but it may also provide information about the clinical evolution of the disease. | 2020-05-05 |
| 32299200 | The symptoms are undiagnostic, the results of viral nucleic acid detection method (PCR) can delay, so that chest computerized tomography is often key diagnostic test in patients with possible COVID-19 pneumonia. | 2020-04-22 |
| 32299201 | The first patients may be lost without a proper diagnosis. | 2020-04-22 |
| 32299304 | Elevated CAS scores were found to be associated with coronavirus diagnosis, impairment, alcohol/drug coping, negative religious coping, extreme hopelessness, suicidal ideation, as well as attitudes toward President Trump and Chinese products. | 2020-05-08 |
| 32300101 | This review summarizes diagnostic value of saliva for 2019-nCoV, possibly direct invasion into oral tissues, and close contact transmission of 2019-nCoV by saliva droplets, expecting to contribute to 2019-nCoV epidemic control. | 2020-04-21 |
| 32300673 | Information on the variation of viruses is of considerable medical and biological impacts on the prevention, diagnosis, and therapy of infectious diseases. | 2020-04-21 |
| 32300823 | Neither image quality nor the handling of the technology are relevant obstacles to a reliable diagnosis. | 2020-05-07 |
| 32300968 | Radiological examinations were confirmed as effective methods for the screening and diagnosis of COVID-19. | 2020-05-01 |
| 32300971 | Rapid and accurate diagnosis of coronavirus disease 2019 (COVID-19) is critical during the epidemic. […] We aim to identify differences in CT imaging and clinical manifestations between pneumonia patients with and without COVID-19, and to develop and validate a diagnostic model for COVID-19 based on radiological semantic and clinical features alone. […] Diagnostic efficacies of developed models were quantified by receiver operating characteristic curve. […] Besides ground-glass opacities (p = 0.032) and consolidation (p = 0.001) in the lung periphery, the lesion size (1-3 cm) is also significant for the diagnosis of COVID-19 (p = 0.027). […] Three diagnostic models achieved an area under the curve value as high as 0.986 (95% CI 0.966~1.000). […] The clinical and radiological semantic models provided a better diagnostic performance and more considerable net benefits. […] A model composed of radiological semantic and clinical features has an excellent performance for the diagnosis of COVID-19. […] • A diagnostic model for COVID-19 was developed and validated using radiological semantic and clinical features, which had an area under the curve value of 0.986 (95% CI 0.966~1.000) and 0.936 (95% CI 0.866~1.000) in the primary and validation cohorts, respectively. | 2020-04-30 |
| 32301099 | We reported on the epidemiological, clinical, laboratory, and radiological characteristics of children cases to help health workers better understand and provide timely diagnosis and treatment. | 2020-05-29 |
| 32301155 | Median age at diagnosis was 71.0 ± 12.8 years, and the median interval since transplantation was 9.3 years. | 2020-05-10 |
| 32301198 | Here, we report the clinical features and our treatment approach for a kidney transplant patient with a diagnosis of COVID-19. | 2020-05-22 |
| 32301631 | OBJECTIVE. This series of patients presented to the emergency department (ED) with abdominal pain, without the respiratory symptoms typical of coronavirus disease (COVID-19), and the abdominal radiologist was the first to suggest COVID-19 infection because of findings in the lung bases on CT of the abdomen. CONCLUSION. COVID-19 infection can present primarily with abdominal symptoms, and the abdominal radiologist must suggest the diagnosis when evaluating the lung bases for typical findings. | 2020-04-17 |
| 32301646 | Background Recent studies have suggested that chest computed tomography (CT) scans could be used as a primary screening or diagnostic tool for coronavirus disease 2019 (COVID-19) in epidemic areas. […] Purpose To perform a meta-analysis to evaluate diagnostic performance measures, including predictive values, of chest CT and initial reverse transcriptase-polymerase chain reaction (RT-PCR). […] Meta-regression was performed to reveal the effect of potential explanatory factors on the diagnostic performance measures. | 2020-04-17 |
| 32301647 | In comparison with clinical model containing only clinical parameters (AUC, 0.83), all three quantitative models showed higher diagnostic performance (AUC 0.86 for all models). | 2020-04-27 |
| 32301692 | Laboratory diagnosis is required to confirm the diagnosis of COVID-19. […] In this review we provide guidance on the diagnosis and management of COVID-19, the influence it has on urological practice and consider the long-term implications that may be of consequence for years to come. | 2020-05-20 |
| 32301745 | Laboratory-based diagnostic tests utilized real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat samples. […] This study evaluated the diagnostic value to analyzing throat and sputum samples in order to improve accuracy and detection efficiency. […] The results can facilitate the selection of specimens and increase the accuracy of diagnosis. | 2020-04-17 |
| 32301749 | Moreover, many patients can be asymptomatic, thus increasing the uncertainty of the diagnostic work-up. […] Laboratory tests play a pivotal role in the diagnosis and management of COVID-19, the current gold standard being real-time reverse transcription polymerase chain reaction (rRT-PCR) on respiratory tract specimens. […] However, the diagnostic accuracy of rRT-PCR depends on many pre-analytical and analytical variables. […] These data represent a pre-requisite for the appropriate utilization of specific antibodies for the diagnosis and management of COVID-19 patients. | 2020-04-17 |
| 32301761 | These patients are more likely to test positive for viral RNA in stool, to have a longer delay before viral clearance, and to experience delayed diagnosis compared with patients with only respiratory symptoms. | 2020-04-23 |
| 32301997 | The patients were divided into three groups according to the “Diagnosis and Treatment of New Coronavirus Pneumonia (6th edition)” issued by the National Health Commission of China. | 2020-04-30 |
| 32302058 | During the SARS-CoV and MERS-CoV epidemics, a variety of molecular and serological diagnostic assays were established and should be referred to for SARS-CoV-2. | 2020-05-19 |
| 32302277 | This mobile RRT laboratory provides a mobile and rapid diagnostic resource when epidemic/pandemic resource allocation may need to be prioritized based on confirmed disease prevalence. | 2020-05-20 |
| 32302284 | They also can address the common problems healthcare workers must overcome to continue working (ie, risk mitigation techniques). | 2020-05-20 |
| 32302459 | The laboratory derangements may be reminiscent of HELLP (hemolysis, elevated liver enzymes, low platelet count) syndrome, and thus knowledge of the COVID-19 relationship is paramount for appropriate diagnosis and management. | 2020-05-26 |
| 32302675 | These evidence provide a molecular structural rationale for a potential role in conferring protection from SARS-CoV-2 infection and identifying potential candidates for the development of diagnostic tools and prophylactic-oriented strategies. | 2020-04-20 |
| 32302813 | Homeless people have less access to health care providers who could otherwise order diagnostic testing and, if confirmed, isolate them from others in coordination with local health departments. | 2020-05-19 |
| 32302927 | As the global pandemic of coronavirus disease-19 (COVID-19) progresses, many physicians in a wide variety of specialties continue to play pivotal roles in diagnosis and management. | 2020-05-22 |
| 32302956 | No unified diagnostic standard has been formulated. […] The initial diagnosis remains based on the positive of nucleic acid tests. […] In accordance with the latest COVID-19 diagnostic criteria, 69 patients diagnosed with COVID-19 treated in the infected V ward of Xiaogan Central Hospital from 2020/1/25 to 2020/2/6 were retrospectively analyzed. | 2020-05-27 |
| 32303575 | Seven days after initial diagnosis, the index patient and the other one from the quarantine retested positive for SARS-CoV-2, although they had been completely asymptomatic for over 96 hours. | 2020-05-31 |
| 32304191 | This review aims to summarize the current epidemics, clinical presentations, diagnosis, and treatment of COVID-19 in pediatric patients. | 2020-04-22 |
| 32304192 | PCR and rapid diagnostic kits are being used to analyze the samples at the central Microbiology Reference Laboratory and the authorized laboratories in several provinces. | 2020-04-22 |
| 32304276 | Urgent joined research efforts regarding the SARS-COV-2 rapid tests, accurate diagnosis, especially early recognition, and effective treatment of life-threatening complications would be highly desirable for humanity and medical workforce all over the world that try to combat a current global pandemic threat. | 2020-05-06 |
| 32304371 | This includes not only the strategy of public surveillance, but also sentinel and event-based surveillance, as it is impossible to actually identify all positive cases; b) Mitigating measures against the spread of the epidemic, such as social distancing and hygiene, washing hands, quarantine, restricting movement and using masks, among others; c) Measures to suppress transmission when the number of cases is very high, such as strict measures to stay at home; d) strengthening health services ‘capacity for medical attention and improving health services’ ability to prevent transmission, including the use of diagnostic tests; e) the development of prophylactic vaccines against Covid-19, as well as the development of therapeutic agents. | 2020-04-18 |
| 32304643 | A significant increase is expected in the number of imaging studies ordered for the initial diagnosis and treatment follow-up of cases of COVID-19. | 2020-05-01 |
| 32305025 | Epidemiological data and laboratory and imaging results were collected on the first day of admission, and analyzed based on the Diagnosis and Treatment Guideline for COVID-19 (5th edition, China). | 2020-05-27 |
| 32305181 | Prevention, diagnosis and treatment of malnutrition should therefore be routinely included in the management of COVID-19 patients. | 2020-05-31 |
| 32305269 | More COVID-19 diagnostic tests should be procured to increase the testing capacity. | 2020-04-21 |
| 32305884 | Studies are rapidly published to share information regarding epidemiology, clinical and diagnostic patterns, and prognosis. | 2020-05-28 |
| 32305937 | Moreover, the computer-aided platforms help radiologists make clinical decisions, i.e., for disease diagnosis, tracking, and prognosis. […] In this review paper, we thus cover the entire pipeline of medical imaging and analysis techniques involved with COVID-19, including image acquisition, segmentation, diagnosis, and follow-up. | 2020-05-01 |
| 32306015 | Tele-medical diagnosis and referral should be developed by local governments during COVID-19. | 2020-04-22 |
| 32306047 | The gold standard for COVID-19 diagnosis was nucleic acid testing for SARS-CoV-2 by RT-PCR. […] The serodiagnostic power of the specific IgM and IgG antibodies against SARS-CoV-2 was investigated in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and consistency rate. […] Antibody detection may play an important role in the diagnosis of COVID-19 as complement approach for viral nucleid acid assays. | 2020-04-30 |
| 32306118 | This study provides a brief and precise review of the current knowledge regarding COVID-19, including disease transmission, clinical characteristics, diagnosis, and potential treatment. | 2020-04-30 |
| 32306597 | Provided strict adherence to the epidemic prevention standards formulated by the state and professional societies, it is necessary to carry out clinical diagnosis and treatment as soon as possible. | 2020-04-20 |
| 32306656 | How to make early diagnosis? | 2020-04-21 |
| 32306836 | In practice, experimental techniques can measure the time and space average properties but they cannot be captured the structural variation of the COVID-19 during the interaction of inhibitor. | 2020-05-06 |
| 32306853 | With the recent emergence of the novel SARS-CoV-2, the availability of rapid, sensitive, and reliable diagnostic methods is essential for disease control. | 2020-05-19 |
| 32306864 | Such information is of immediate relevance and would assist COVID-19 clinical diagnosis, prognosis and vaccine design. | 2020-05-05 |
| 32307014 | Therefore, the People’s Liberation Army Professional Committee of Critical Care Medicine and Chinese Society on Thrombosis and Hemostasis grouped experts from the frontline of the Wuhan epidemic to come together and develop an expert consensus on diagnosis and treatment of coagulation dysfunction associated with a severe COVID-19 infection. | 2020-04-23 |
| 32307298 | The diagnosis of hemophagocytic lymphohistiocytosis (HLH) with cerebral involvement is challenging given the rarity of HLH and its resemblance to the much more common severe sepsis. […] Timely diagnosis and treatment may be lifesaving. […] OBJECTIVE: To raise awareness about the importance of early diagnosis and treatment of HLH with neurological involvement to prevent serious complications and demise. | 2020-04-23 |
| 32307320 | COVID-19 pneumonia presented with certain characteristic chest CT imaging features, which are helpful to the radiologist in the early detection and diagnosis of this emerging global health emergency. | 2020-05-13 |
| 32307322 | Current diagnosis is based mainly on typical ground glass opacities on chest CT, epidemiological suspicion and contact tracing. | 2020-05-13 |
| 32309266 | In line with the current opinion of the WHO, we strongly believe that preventive measures and early diagnosis of COVID-19 are crucial to interrupt virus spread and avoid local outbreaks. | 2020-04-22 |
| 32309267 | In the current epidemiological context, clinical and biological work-up led to a diagnosis of COVID-19 infection. | 2020-05-27 |
| 32309388 | We report the screening and diagnosis of corona virus disease 2019 (COVID-19) in our hospital. | 2020-04-23 |
| 32310621 | In this review, we summarize epidemiologic, clinical and diagnostic findings, as well as treatment and prevention options for common circulating and novel CoVs infections in humans with a focus on infections in children. | 2020-04-24 |
| 32310816 | Rather, the surgeon invites the patient to assess the wound, which opens up a sequence of patient and physician assessments where diagnostic criteria such as redness or swollenness are made explicit. | 2020-05-06 |
| 32310920 | The integrated clinical, laboratory and ultrasound approach is essential for the diagnosis, monitoring and evaluation of the patient’s therapy in COVID-19 pneumonia. | 2020-04-22 |
| 32310921 | If this, on one hand, results in reducing improper access to the ER and hospital, on the other hand it substantiates the risk of underestimating problems not connected to COVID-19, such as an increased delay in the diagnosis and treatment of acute myocardial infarction and other cardiovascular emergencies. | 2020-04-22 |
| 32311047 | COVID-19 data flowing across geographic borders are extremely useful to public health professionals for many purposes such as accelerating the pharmaceutical development pipeline, and for making vital decisions about intensive care unit rooms, where to build temporary hospitals, or where to boost supplies of personal protection equipment, ventilators, or diagnostic tests. | 2020-04-30 |
| 32311303 | Preoperative testing for COVID-19, limited operating room personnel, adequate personal protective equipment, and surgical technique are factors to consider for high-risk procedures. Methods: This article presents the case of an awake tracheotomy performed for a transglottic mass causing airway obstruction. Results: With detailed planning and specific techniques, the amount of aerosolization was reduced, and the procedure was performed as safely as possible. Conclusion: This case provides a template for future aerosol-generating procedures during respiratory pandemics. | 2020-05-13 |
| 32311350 | All studies of pregnant women who received a coronavirus disease 2019 diagnosis using acid nucleic test, with reported data about pregnancy, and, in case of delivery, reported outcomes, were included. | 2020-05-16 |
| 32311437 | Real-time fluorescence quantitative reverse transcriptase polymerase chain reaction (reverse transcriptase-polymerase chain reaction,RT-PCR) and viral gene sequencing are the gold standard for the diagnosis of COVID-19. […] COVID-19 diagnostic criteria: according to China’s ⟪pneumonia diagnosis and treatment Program of novel coronavirus infection (trial version 7) ⟫, in accordance with the relevant epidemiological and clinical manifestations, nasopharyngeal swabs real-time fluorescence RT-PCR detection of 2019-nCoV nucleic acid positive, COVID-19 cases were divided into mild, ordinary, severe and severe [1]. | 2020-05-13 |
| 32311451 | The study also highlights the necessity of taking stool samples for suspected patients to help in early diagnosis and assessment of disease status. | 2020-05-31 |
| 32311826 | In addition to its central role in the diagnosis of COVID-19 infection, the clinical laboratory provides critical information to clinicians regarding prognosis, disease course, and response to therapy. […] The purpose of this review is to 1) provide background context about the origins and course of the pandemic 2) discuss the laboratory’s role in the diagnosis of COVID-19 infection 3) summarize the current state of biomarker analysis in COVID-19 infection, with an emphasis on markers derived from the hematology laboratory 4) comment on the impact of COVID-19 on hematology laboratory safety, and 5) describe the impact the pandemic has had on organized national and international educational activities worldwide. | 2020-04-20 |
| 32311836 | Analysis compared responses by diagnosis, disease activity, and new onset of symptoms. […] Of the 7061 participants invited to participate, 530 responded, with RA as the most frequent diagnosis (61%). | 2020-05-09 |
| 32312018 | The COVID-19 poses significant threats to international health.Computed tomography (CT) has been an important imaging modality in assisting in the diagnosis and management of patients withCOVID-19. | 2020-04-23 |
| 32312025 | Computed tomography (CT) has been described as a diagnostic modality in the COVID-19 diagnosis and treatment plan. […] While sensitive for detecting lung parenchymal abnormalities in COVID-19 pneumonia, CT for initial diagnosis is discouraged and should be reserved for specific clinical indications. | 2020-04-21 |
| 32312064 | As two important means of examination, computed tomography (CT) and real-time reverse transcription polymerase chain reaction (RT-PCR) have always been controversial in the clinical diagnosis of COVID-19 pneumonia. […] Here, we report a family cluster case of a father and a son diagnosed as COVID-19 at our hospital, and described the clinical manifestations, laboratory results, CT changes, diagnosis and treatment strategy of these two patients. […] Focus on the value of these two methods in the diagnosis and treatment of diseases, as well as their respective deficiencies. […] For patient 1 (father), the efficacy of RT-PCR is not satisfactory either in terms of diagnosis or follow-up, which may cause misdiagnosis and delay treatment. | 2020-04-21 |
| 32312290 | Two patient groups were simulated (50,000 patients in each group); (1) Patients received tPA immediately upon diagnosis of ARDS and (2) patients received standard therapy for ARDS. | 2020-04-23 |
| 32312568 | Based on our own experience and the guidelines on the diagnosis and treatment of COVID-19 (7th Version) with other regulations and literature, we describe our experience with suggestions for medical practices for burn units during the COVID-19 outbreak. | 2020-04-23 |
| 32312574 | The overlap in the signs and symptoms of COVID-19 associated Acute Respiratory Distress Syndrome (ARDS) and COVID-19 with concurrent pulmonary embolism creates a diagnostic challenge for emergency medicine physicians in patients already at risk for renal impairment. | 2020-04-26 |
| 32312628 | The electrodiagnostic test showed that the patient is an AMSAN variant of GBS. | 2020-04-23 |
| 32312676 | Surgical techniques should be adapted to limit the risk of viral dissemination in the air, avoiding the use of drills, microdebriders, monopolar cautery or lasers. | 2020-05-22 |
| 32313296 | We have applied a computational strategy, using a combination of virtual screening, docking and molecular dynamics techniques, aimed at identifying possible lead compounds for the non-covalent inhibition of the main protease 3CLpro of the SARS-CoV2 Coronavirus. | 2020-05-14 |
| 32313588 | The utility of the noncontrast CT chest in the diagnosis of COVID-19 has been controversial, but there are specific imaging findings that have been increasingly associated with this virus in the appropriate clinical context. | 2020-05-31 |
| 32313785 | Saliva has an immense potential as a diagnostic fluid and offers an edge over other biological fluids as its collection method does not require invasive procedure, economical and is useful for monitoring systemic health. […] Development of sensitive and precise salivary diagnostic tools and the formulation of defined guidelines following meticulous testing will allow salivary diagnostics to be utilised as chair side tests for various oral and systemic diseases in the near future. […] Rapid and accurate diagnosis of Covid-19 is crucial in controlling the outbreak in the community and in hospitals. […] Nasopharyngeal and oropharyngeal swabs are the recommended specimen types for Covid-19 diagnostic testing. […] Salivary diagnostics is a dynamic field that is being incorporated as part of disease diagnosis, clinical monitoring of systemic health and to make significant clinical decisions for patient care. […] More research is required to analyze the potential diagnostic of Covid-19 in saliva to develop rapid chair side tests for the detection of Covid-19 and it is also pivotal to improve and develop successful strategies for prevention, especially for dentists and healthcare professionals who are involved in performing aerosol-generating procedures. | 2020-04-23 |
| 32313822 | There are two diagnostic tests for coronavirus infection i.e. molecular test and serology test. | 2020-04-23 |
| 32313828 | In this perspective, to support the National Health Care System and to minimize the impact of this rapidly spreading virus, the Italian Ministry of Health involved the Istituti Zooprofilattici Sperimentali (IZSs), Veterinary Public Health Institutes, in the diagnosis of SARS-CoV-2 by testing human samples. | 2020-05-30 |
| 32313886 | Based on his medical history and current presentation, he received a diagnosis of SSD. | 2020-05-20 |
| 32314050 | Both percutaneous and open techniques can be performed safely with careful modifications to technique and appropriate enhanced personal protective equipment. | 2020-04-30 |
| 32314058 | This document from the European Society of Radiology (ESR) and the European Society of Thoracic Imaging (ESTI) aims to present the main imaging features, and the role of CT scan in the early diagnosis of COVID-19, describing, in particular, the typical findings which make it possible to identify the disease and distinguish it from bacterial causes of infection, and to define which category of patients may benefit from CT imaging. | 2020-04-29 |
| 32314249 | Correct diagnosis and management in the postoperative setting would be challenging. | 2020-04-23 |
| 32314685 | His atypical presentation led to a delay in diagnosis, but ultimately he was isolated and tested. […] On confirming the diagnosis of COVID-19, the patient was isolated in a separate hospital with a dedicated medical care team. | 2020-04-21 |
| 32314699 | The initial testing strategy resulted in delays in both diagnosis and implementation of appropriate precautions. | 2020-04-21 |
| 32315171 | It is very efficient to apply computer-aided drug design techniques to quickly identify promising drug repurposing candidates, especially after the detailed 3D structures of key viral proteins are resolved. | 2020-05-07 |
| 32315725 | The decreased levels of T lymphocyte subsets reported in our study were similar with SARS but not common among other virus infection, which may be possible biomarkers for early diagnosis of COVID-19. | 2020-04-26 |
| 32315907 | Also, the evaluation of current treatments for wastewater and sewage sludge, as well as the eventual development of new specific techniques, based on sorption, nanotechnology, etc., would be of great interest for controlling the environmental dissemination of these viruses in the current and eventual future outbreaks. | 2020-05-29 |
| 32316233 | To enable the World Health Organization include appropriate G6PD POC diagnostic tests in its list of essential in-vitro diagnostics for use in resource-limited settings, we recommend a wider evaluation of available POC diagnostic tests for G6PD deficiency, particularly in malaria-endemic countries. | 2020-05-29 |
| 32316618 | The purpose of this review is to provide a comprehensive update on the pathogenesis, clinical aspects, diagnosis, challenges and treatment of SARS-CoV-2 infections. | 2020-05-29 |
| 32316712 | The aims were to investigate medical needs of lung cancer patients and their mental health status during the epidemic periods, so as to provide rational recommendations for subsequent diagnosis and treatment. | 2020-05-16 |
| 32317153 | According to COVID-19 prevention and control policy and requirements, combined with series of diagnosis and treatment plans, pharmacists in the first provincial-level COVID-19 diagnosis and treatment unit in Jilin Province in Northeast China have established the management practices of drug supply and pharmaceutical care from four aspects: personnel, drugs supply management, off-label drug use management and pharmaceutical care. | 2020-04-24 |
| 32317257 | Diagnostic testing for COVID-19 is central to controlling the global pandemic. | 2020-04-22 |
| 32317409 | This would help in the development of diagnostic assays for novel viruses with outbreak potential and be useful in disease interventions. | 2020-05-06 |
| 32317557 | Data captured included patient characteristics, pre-COVID-19 risk factors and comorbidities, confirmation of COVID-19 diagnosis, features of ECMO support, specific medications utilized to treat COVID-19, and short-term outcomes through hospital discharge. | 2020-05-15 |
| 32317558 | The diagnosis was established through a remote interaction with the patient after early discharge from outpatient therapy due to upcoming traveling restrictions. | 2020-05-26 |
| 32317591 | ICU of a university-affiliated hospital from northern Italy dedicated to care of patients with confirmed diagnosis of coronavirus disease 2019. […] Ten intubated patients with acute respiratory distress syndrome and confirmed diagnosis of coronavirus disease 2019. | 2020-04-30 |
| 32317810 | The emerging trends in SARS-CoV-2 genome data show specific mutation and genetic diversity, which could provide the basis to develop a cocktail of vaccine and may also be used to develop the region-specific diagnostic tool, thus decreasing the chances of testing failures in fields. | 2020-04-24 |
| 32318325 | The objectives of this study were to analyze the clinical features of coronavirus disease 2019 (COVID-19) and evaluate the diagnosis and treatment. | 2020-04-24 |
| 32318703 | The median period from contact to diagnosis and the last positive nucleic acid test was 19 (8-24 days) and 21.5 days (10-36 days), respectively. […] The median period from diagnosis to negative nucleic acid test was significantly different between patients with normal or atypical chest computed tomography (CT) findings (n=16, 61.5%; 7.5 days [2-20 days]) and patients with typical ground-glass or patchy opacities on CT(n=10, 38.5%; 12.5 days[8-22 days]; P<0.01). | 2020-04-30 |
| 32318891 | The sonographic signs are non-specific when considered alone, but observation of some aspects of vertical artifacts can enhance the diagnostic power of the ultrasound examination. | 2020-04-24 |
| 32319446 | An early diagnosis associated with an appropriate therapeutic action in the initial stages of the disease can reduce the progression of CoViD-19 towards interstitial pneumonia, thus interfering with the number of transfers to intensive care and lethality of the pandemic in progress. | 2020-04-24 |
| 32319971 | Due to the lack of current effective treatment and vaccine for COVID-19, screening, rapid diagnosis and isolation of the patients are essential (1, 2). | 2020-04-22 |
| 32320064 | The goal of this study was to assess the diagnostic values of different methods of detecting and estimating the SARS-CoV-2 infection, and the auxiliary diagnostic potential of antibody assays. | 2020-04-22 |
| 32320375 | Emerging infectious diseases by their nature, pose new challenges to the diagnostic-treatment-control nexus, and push our concepts of causality beyond the limits of the conventional Koch-Henle approach to aetiology. | 2020-05-29 |
| 32320809 | Using daily time series of COVID-19 incidence, we illustrate how epidemic curves of reported cases may not always reflect the true epidemic growth rate due to changes in testing rates, which could be influenced by limited diagnostic testing capacity during the early epidemic phase. | 2020-05-20 |
| 32323011 | • CT can play an early warning role in the diagnosis of COVID-19 in the case of no epidemic exposure. […] • CT could be used for the differential diagnosis of influenza and COVID-19 with satisfactory accuracy. | 2020-05-01 |
| 32323016 | The ultimate decision on the approach should be made after considering the proven benefits of laparoscopic techniques versus the potential theoretical risks of aerosolization. | 2020-05-14 |
| 32323908 | Not only will this allow us to continue our strong history of education, it will enhance our strong commitment to using modern educational techniques and tools to address the genetics workforce issues that have defined the recent past. | 2020-05-29 |
| 32323974 | Simple and rapid immunodiagnostic methods are urgently needed to identify positive cases. […] The results of the validation experiment met the requirements for clinical diagnostic reagents. | 2020-05-21 |
| 32324101 | This report summarizes evidence for thromboembolic disease, potential diagnostic and preventive actions as well as recommendations for patients with COVID-19 infection. | 2020-04-23 |
| 32324331 | We describe the case of a 61-year-old kidney transplant recipient with several comorbidities who was hospitalized and later received a diagnosis of COVID-19 pneumonia; the infection was successfully managed with the use of hydroxychloroquine and a single administration of tocilizumab, after immunosuppression reduction; the patient did not require mechanical ventilation. | 2020-05-13 |
| 32324359 | Here below, we focus mainly on the diagnostic issues of COVID-19 and on the estimation of the prognosis. […] We also focus on the proper method of microbiological sampling and the relevant informations regarding diagnostic tests like the gold standard real-time reverse transcriptase polymerase chain reaction (RT-PCR) for SARS-CoV-2. | 2020-04-27 |
| 32324360 | Thus, imaging techniques are situated in the frontline to aim the diagnostic decision-making, to follow up the progress and to evaluate the possible complications. | 2020-04-27 |
| 32324451 | There is a need for medical and scientific expertise to clinically and sociologically contextualize and interpret diagnostic tests as well as drugs and vaccines that will be deployed in the coming months as part of the planetary collective response to the COVID-19 pandemic. | 2020-04-23 |
| 32324653 | We also anticipate that some patients will have incidentally detected findings that could be attributable to COVID-19 pneumonia, requiring radiologists to decide whether or not to mention COVID-19 specifically as a differential diagnostic possibility. | 2020-05-30 |
| 32325718 | Healthcare workers exposed to coronavirus (COVID-19) may not have adequate access to personal protective equipment (PPE), safety procedures, and diagnostic protocols. […] The vast majority (n = 707; 75.5%) had access to personal safety policies and procedures, and 699 (74.7%) participants had access to diagnostic algorithms. | 2020-04-29 |
| 32326343 | While great resources are understandably being dedicated to treatment and diagnosis, more efforts could be dedicated to limit the virus spread. | 2020-05-23 |
| 32327245 | The purpose of this study was to distinguish the imaging features of COVID-19 from those of other infectious pulmonary diseases and evaluate the diagnostic value of chest CT for suspected COVID-19 patients. […] The combinations with GGOs could be useful in the identification and differential diagnosis of COVID-19, alerting clinicians to isolate patients for prompt treatment and repeat RT-PCR tests until the end of incubation. | 2020-04-27 |
| 32327383 | Ultrasound, although not used in the diagnosis of COVID-19 may be utilised by practitioners at the point of care (POC) or on the intensive care units (ITUs) where rapid assessment of the lung condition may be required. […] Ultrasound is being used in Italy and China to help review lung condition during the COVID-19 outbreak however not strictly as a diagnostic tool as Computed Tomography (CT) of the chest and chest radiographs are currently gold standard. […] However it should not be used as a diagnostic tool for COVID-19 due to low specificity in relation to the virus. | 2020-04-27 |
| 32327448 | Scarborough, ME) is a rapid diagnostic test that can be performed in a point of care setting equivalent to CLIA waived testing. | 2020-04-24 |
| 32327904 | Many of the medications used for treatment of COVID-19 can also be associated with GI symptoms or liver injury and can be included in the differential diagnosis in these patients. […] Although the diagnosis of the infection is currently based on RNA analysis in respiratory samples, the available literature on fecal shedding of this virus suggests that fecal RNA testing might prove to be a useful diagnostic test. | 2020-04-27 |
| 32328954 | Diagnostic criteria and the identification of persons under investigation have evolved as more data has emerged. […] However, the approach to diagnosis is still very variable from region to region, country to country, and even among different hospitals in the same city. […] The importance of a clinical pathway to implement the most effective and relevant diagnostic strategy is of critical importance to establish the control of this virus that is responsible for more and more deaths each day. | 2020-05-08 |
| 32329026 | Although this should be interpreted cautiously, it may be possible that either the viral clearance kinetics in these matrices matches the progressive clinical recovery of the patient or that the virus was never present in these fluids at the time of the laboratory diagnosis. | 2020-05-07 |
| 32329102 | Indeed, there is urgent need to develop and deploy robust diagnostic methodologies not only to use in health laboratory environments but also directly in places where humans circulate and spread the virus such as airports, trains, boats, and any public aggregation places. […] The success of a reliable and sensitive asymptomatic diagnosis relies on the identification and measurement of informative biomarkers from human host and virus in a rapid, sensitive, and inexpensive manner. | 2020-05-27 |
| 32329275 | All articles were categorized into epidemiology, clinical diagnosis and treatment, basic research, pregnant women and children, mental health, epidemic prevention & control, and others. | 2020-04-27 |
| 32329276 | In this review we introduce these research works related to spike proteins, hoping it will provide reasonable ideas for the control of the current pandemic, as well as for the diagnosis and treatment of COVID-19. | 2020-04-27 |
| 32329432 | Reverse transcriptase-polymerase chain reaction testing, our primary diagnostic tool to date, has sensitivity and timing concerns, owing to sampling/handling errors, as well as a complex virus-host interaction. | 2020-05-06 |
| 32329659 | Concerns about the prevention and management of COVID-19 are on the rise, as it is crucial in contagious epidemics that travel and transfer of the patients be minimal for diagnosis, treatment, and follow-ups. | 2020-04-24 |
| 32329877 | In this crisis, a collective pool of knowledge about the advancement of clinical diagnostic and management for COVID-19 is a prerequisite. […] Here, we summarize all the available updates on the multidisciplinary approaches for the advancement of diagnosis and proposed therapeutic strategies for COVID-19. […] Advances in various diagnostic approaches, such as the use of real-time polymerase chain reaction (RT-PCR), chest radiography, and computed tomography (CT) imaging; and other modern diagnostic methods, for this infection have been highlighted. […] Collectively, the review provides an overview of the SARS-CoV-2 infection outbreak along with the recent advancements and strategies for diagnosis and therapy of COVID-19. | 2020-04-30 |
| 32329881 | This is a case series of patients with a confirmed diagnosis of SARS-CoV2 infection and severe pneumonia or ARDS who were treated with up to 4 infusions of eculizumab as an off-label agent. | 2020-04-29 |
| 32329958 | Multidisciplinary conferences (MDC) are an important component of head and neck oncologic care including diagnosis, treatment, and survivorship. | 2020-05-29 |
| 32330078 | Dental professionals may play an important role in early identification and diagnosis of patients with COVID-19. | 2020-04-24 |
| 32330124 | With the current rapid spread of COVID-19, global health systems are increasingly overburdened by the sheer number of people that need diagnosis, isolation and treatment. | 2020-04-29 |
| 32330291 | Though molecular diagnostic tests are the gold standard for COVID-19, serological testing is emerging as a potential surveillance tool, in addition to its complementary role in COVID-19 diagnostics. | 2020-05-11 |
| 32330303 | Nucleic acid testing is the standard method for the diagnosis of viral infections. […] The IgM-IgG test is an accurate and sensitive diagnostic method. […] A combination of nucleic acid and IgM-IgG testing is a more sensitive and accurate approach for diagnosis and early treatment of COVID-19. | 2020-05-08 |
| 32330313 | Diagnosis of late pregnancy with asymptomatic COVID-19 infection was made. | 2020-04-30 |
| 32330340 | The diagnosis is made employing quantitative reverse transcriptase polymerase chain reaction to identify the viral nucleic acid in respiratory specimens or blood samples. | 2020-04-24 |
| 32330356 | We describe each patient’s medical history including transplantation history, their clinical presentation and workup, and their course from diagnosis to either hospital discharge or to improvement in symptoms. | 2020-05-08 |
| 32330414 | Utilizing two complementary sequencing techniques, we present a high-resolution map of the SARS-CoV-2 transcriptome and epitranscriptome. | 2020-05-19 |
| 32330437 | We searched at the Brazilian Health Regulatory Agency (ANVISA) online platform to describe the pooled sensitivity (Se), specificity (Sp), diagnostic odds ratio (DOR) and summary receiver operating characteristic curves (SROC) for detection of IgM/IgG antibodies and for tests using naso/oropharyngeal swabs in the random-effects models. […] Pooled diagnostic accuracy measures [95%CI] were: (i) for IgM antibodies Se=82% [76-87]; Sp=97% [96-98]; DOR=168 [92-305] and SROC=0.98 [0.96-0.99]; (ii) for IgG antibodies Se=97% [90-99]; Sp=98% [97-99]; DOR=1994 [385-10334] and SROC=0.99 [0.98-1.00]; and (iii) for detection of SARS-CoV-2 by antigen or molecular assays in naso/oropharyngeal swabs Se=97% [85-99]; Sp=99% [77-100]; DOR=2649 [30-233056] and SROC=0.99 [0.98-1.00]. […] Future studies addressing the diagnostic performance of tests for COVID-19 in the Brazilian population are urgently needed. | 2020-04-28 |
| 32330439 | Diagnosis for acute disease was confirmed with RT-PCR testing. | 2020-04-27 |
| 32330458 | When a new infectious disease emerges, appropriate case definitions are important for clinical diagnosis and for public health surveillance. | 2020-05-13 |
| 32331519 | His chest computed tomography was performed and showed bilateral multifocal ground-glass opacities with consolidation, which suggested viral pneumonia as a differential diagnosis. | 2020-04-28 |
| 32331845 | We discuss and propose mitigation strategies for: the risk of COVID-19 infection and its associated morbidity and mortality for individuals with ADRD; the impact of COVID-19 on the diagnosis and clinical management of ADRD; consequences of societal responses to COVID-19 in different ADRD care settings; the effect of COVID-19 on caregivers and physicians of individuals with ADRD; mental hygiene, trauma, and stigma in the time of COVID-19; and the potential impact of COVID-19 on ADRD research. | 2020-04-28 |
| 32332061 | As part of the worldwide response, many molecular diagnostic platforms have been granted Emergency Use Authorization (EUA) by the Food and Drug Administration (FDA) to identify SARS-CoV-2 positive patients. […] Our objective was to evaluate three sample-to-answer molecular diagnostic platforms (Cepheid Xpert® Xpress SARS-CoV-2 [Xpert Xpress], Abbott ID NOW™ COVID-19 [ID NOW], GenMark ePlex® SARS-CoV-2 Test [ePlex]) to determine analytical sensitivity, clinical performance, and workflow for the detection of SARS-CoV-2 in nasopharyngeal swabs from 108 symptomatic patients. | 2020-04-25 |
| 32332765 | As these fusion proteins exhibit cross-reactivity against coronaviruses, they have potential applications in the diagnosis, prophylaxis, and treatment of SARS-CoV-2. | 2020-04-28 |
| 32333222 | In this review, we introduced current diagnostic methods and criteria for the SARS-CoV-2 in China and discuss the advantages and limitations of the current diagnostic methods, including chest imaging and laboratory detection. | 2020-05-01 |
| 32333248 | In the early February, 2020, we called up an experts’ committee with more than 30 Chinese experts from 11 national medical academic organizations to formulate the first edition of consensus statement on diagnosis, treatment and prevention of coronavirus disease 2019 (COVID-19) in children, which has been published in this journal. […] With accumulated experiences in the diagnosis and treatment of COVID-19 in children, we have updated the consensus statement and released the second edition recently. […] The current version in English is a condensed version of the second edition of consensus statement on diagnosis, treatment and prevention of COVID-19 in children. […] In the current version, diagnosis and treatement criteria have been optimized, and early identification of severe and critical cases is highlighted. […] This version of experts consensus will be valuable for better prevention, diagnosis and treatment of COVID-19 in children worldwide. | 2020-05-01 |
| 32333544 | Further studies are needed to evaluate the utility of lung ultrasound in the diagnosis and management of COVID-19. | 2020-05-06 |
| 32333644 | To curb the spreading of the virus, WHO urgently demanded an extension of screening and testing; thus, a rapid and simple diagnostic method is needed. | 2020-04-25 |
| 32333860 | Soluble cluster of differentiation (CD)14 subtype (sCD14-ST also termed presepsin PSP) is a regulatory factor that modulates immune responses by interacting with T and B cells, useful for early diagnosis, prognosis and risk stratification prediction. | 2020-05-18 |
| 32333929 | Major issues for patients with ILD will include restricted access to key components of the diagnostic process, new uncertainties in the use of common ILD pharmacotherapies, limited ability to monitor both disease severity and the presence of medication adverse effects, and significantly curtailed research activities. […] The purpose of this review is to summarize how COVID-19 has impacted key components of the diagnosis and management of fibrotic ILD as well as to provide strategies to mitigate these challenges. | 2020-05-10 |
| 32334323 | In this manuscript we provide guidance to prepare for the impact of COVID-19 pandemic on breast cancer patients and advise on how to triage, prioritize and organize diagnostic procedures, surgical, radiation and medical treatments. | 2020-05-29 |
| 32334905 | The ability to perform diagnostic tests in all suspect patients would also allow us to refine our procedures. | 2020-04-28 |
| 32335089 | The detection of SARS-CoV-2 RNA by real-time reverse transcription-polymerase chain reaction (rRT-PCR) is used to confirm the clinical diagnosis of COVID-19 by molecular diagnostic laboratories. | 2020-05-18 |
| 32335200 | From 673 valid questionnaires, we found that 10.8% of respondents met the diagnosis of post-traumatic stress disorder (PTSD) after returning to work. | 2020-04-29 |
| 32335426 | Early detection, isolation, diagnosis, and treatment are the most effective means of prevention and control. […] The current gold standard for the diagnosis of COVID-19 is the detection of coronavirus nucleic acids, but imaging has an important role in the detection of lung lesions, stratification, evaluation of treatment strategies, and differentiation of mixed infections. | 2020-05-15 |
| 32335585 | Real-time reverse-transcription polymerase chain reaction (rRT-PCR) screening is considered as the standard laboratory test for the diagnosis of COVID-19. | 2020-04-28 |
| 32336317 | Currently, various diagnostic kits to test for COVID-19 are available, and repurposing therapeutics for COVID-19 has shown to be clinically effective. | 2020-04-29 |
| 32336564 | The great pulmonary affectation produced by the COVID-19 infection, requires a fast diagnostic tool that complements the diagnostic test by PCR and which is also useful in evaluating the progression of lung lesions. […] Since most of these are peripheral, in this consensus document we propose the use of thoracic ultrasound for early diagnosis and for the daily evaluation of the progression of lung lesions by a single explorer without the need to use the chest CT. | 2020-04-29 |
| 32336594 | Since containment of the outbreak may have partially failed due to asymptomatic transmission, it is imperative to accelerate the development of rapid point-of-care diagnostic tests, vaccines, and therapeutics for the COVID-19 epidemic. | 2020-04-30 |
| 32336959 | While knowledge regarding epidemiologic features and diagnostic tools of coronavirus disease 2019 (COVID-19) is rapidly evolving, uncertainties surrounding various aspects of its optimal management strategies persist. | 2020-05-06 |
| 32337113 | In this study, we will provide a brief review of viral origin, identification, symptoms, transmission, diagnosis, and potential treatment strategies for the newly identified SARS-CoV-2 strain. | 2020-04-30 |
| 32337143 | Some preventive strategies of the disease include blocking the routes of transmission of the infections, disinfection of instruments used during medical case handling, using personal protective equipment, proper and early diagnosis of the disease, avoiding contact with the sick patients, and quarantine of the infected/exposed people. | 2020-04-30 |
| 32337148 | We need more research in Covid-19 patients with cardiovascular involvement for early diagnosis, prevention of exposure to health care workers and effective treatment. | 2020-04-30 |
| 32337201 | Careful acquisition of an epidemiological history is necessary to make a correct diagnosis and strategize a treatment plan. | 2020-04-30 |
| 32337662 | Extensive experiments are performed by considering the proposed and the competitive machine learning techniques on the chest CT images. | 2020-05-07 |
| 32337664 | In this paper, we will elaborate the role of cytokine storm in COVID-19, the mechanism of tocilizumab on cytokine storm and the key points of pharmaceutical care based on the actual clinical application for COVID-19 in our hospital, the latest research reports, clinical trial progress of tocilizumab, drug instruction from the US FDA, and “Diagnosis and Treatment Plan of Novel Coronavirus Pneumonia (seventh trial edition)” in China, so as to provide reference for the treatment of COVID-19. | 2020-05-28 |
| 32337795 | Although chest Computer Tomography (CT) represents the gold standard to assess lung involvement, with a specificity even superior to the nasal/pharyngeal swab for diagnosis, lung ultrasound examination can be a valid alternative to CT scan, with some advantages, particularly desirable for pregnant women. | 2020-04-27 |
| 32338347 | Diagnosis can be confirmed by Reverse transcriptase - Polymerase chain reaction (RT-PCR) on respiratory specimen (commonly nasopharyngeal and oropharyngeal swab). […] Rapid progress is being made to develop rapid diagnostic tests, which will help ramp up the capacity to test and also reduce the time to getting test results. | 2020-05-19 |
| 32339082 | The resulting area under the receiver operating characteristics curve (AUC) was compared to results from RT-PCR and clinical diagnosis of COVID-19. […] The average AUC was 0.91 (95% CI 0.85-0.97) for predicting RT-PCR outcome and 0.95 (95% CI 0.91-0.99) for clinical diagnosis. | 2020-04-27 |
| 32339231 | Incubation period and interval times were calculated using dates of the following events: contact with an infected person, onset, first visit and diagnosis. […] In addition, the lengths of the intervals between onset and diagnosis, onset and first visit, and first visit and diagnosis decreased over time. | 2020-05-06 |
| 32339260 | We discuss how preventative and control measures implemented during the COVID-19 crisis could affect the prevalence of anaemia, and highlight issues regarding the diagnosis and treatment of anaemia in patients requiring elective or emergency surgery. | 2020-05-06 |
| 32339487 | In severe ICU group, patients have the lowest count of lymphocytes, but the highest neutrophil count and NLR among the above three groups (all P values < 0.05); NLR and MLR indicators were combined for diagnostic efficacy analysis of severe COVID-19, and its area under the curve reached 0.925. | 2020-05-18 |
| 32339662 | This perspective paper reviews the following: current COVID-19 epidemiology, diagnosis, and potential therapies; care considerations unique to HCT recipients; and the concept of a learning network to assimilate emerging guidelines and best practices and to optimize patient outcomes through facilitating shared learning and experience across transplantation centers. | 2020-05-07 |
| 32339723 | The estimated diagnosis dates of deaths and cured cases were calculated based on median cure time or median death time of individual cases. […] Afterward, instant fatality rate was calculated according to the number of deaths and cured cases on the same estimated diagnosis date. | 2020-04-29 |
| 32340018 | The difficulties in diagnosis, infection control, and treatment of COVID-19 in maintenance HD patients are discussed in this report. | 2020-04-27 |
| 32340091 | Objective: By describing and analyzing the epidemic characteristics and trends of the attack rate, the crude mortality and relevant indexes in Hubei province during the pandemic of COVID-19 to provide comprehensive evaluations of the epidemic trends and the effects of intervention measures. Methods: Based on the case data reported in Hubei province during the COVID-19 epidemic, combined with the important time of major interventions and event, the cumulative attack rate, the sequential increase rate of new cases, baseline increase rate of new cases, the observation- confirmed case conversion rate, the cumulative crude mortality, the daily severe case rate, and the ratio of death to severe were used to describe and analyze the epidemic characteristics in different phases of the COVID-19 epidemic. Results: The epidemic experienced an outbreak phase from January 10 to February 3 with large amount of case reported, a peak phase from February 4 to February 19 with continuous increasing number of new cases and deaths, a platform phase from February 20 to March 3 with balanced diagnosis and treatment number, and a descending phase from March 4 to March 18 with decreased diagnosis and increased treatment number. | 2020-04-28 |
| 32340096 | The previous diagnosis of hypertension was clear. | 2020-04-28 |
| 32340107 | This commentary explores the potential of implementing digital technologies that can be used at different stages of the COVID-19 outbreak, including data-driven disease surveillance, screening, triage, diagnosis, and monitoring. | 2020-04-30 |
| 32340389 | We identified potent Mpr inhibitors employing computational techniques that entail the screening of a Marine Natural Product (MNP) library. […] Molecular dynamics and re-docking further confirmed the results obtained by structure-based techniques and allowed this study to highlight some crucial aspects. | 2020-04-29 |
| 32340541 | When possible, alternative diagnostic and treatment strategies should be pursued. | 2020-04-28 |
| 32340555 | We analyzed the first 237 entries, which revealed that anosmia was noted in 73% of patients prior to COVID-19 diagnosis and was the initial symptom in 26.6%. | 2020-04-28 |
| 32340751 | They are recommendations in continuous review and can be modified if the epidemiological situation, the diagnostic and therapeutic options so require. | 2020-04-30 |
| 32340833 | In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed. | 2020-05-05 |
| 32340912 | In consideration of the crucial role of diagnostic testing during COVID-19, the aim of this technical note was to provide a complete synthesis of approaches implemented for the management of suspected or confirmed COVID-19 patients. | 2020-04-30 |
| 32341078 | With the surge in COVID-19 cases worldwide, the medical community should be aware of atypical clinical presentations to help with correct diagnosis, to take the proper measures to place the patient in isolation and to avoid healthcare professionals being infected by coronavirus (SARS-CoV-2). […] In our case series, CT scan findings helped us to suspect the correct diagnosis, which was subsequently confirmed with COVID-19 RT-PCR tests. | 2020-04-28 |
| 32341143 | In the present study, we have evaluated the analytical sensitivity and clinical performance of four SARS-CoV-2 molecular diagnostic assays granted Emergency Use Authorization by the FDA using nasopharyngeal swabs from symptomatic patients: the New York SARS-CoV-2 Real-time Reverse Transcriptase (RT)-PCR Diagnostic Panel (Modified CDC), the Simplexa COVID-19 Direct (Diasorin Molecular), GenMark ePlex SARS-CoV-2 assay (GenMark) and the Hologic Panther Fusion® SARS-CoV-2 assay (Hologic). | 2020-04-28 |
| 32341311 | Future directions include the development of validated, modified examination techniques and new technology that will allow for improved interactive physical examinations, as we rapidly move forward into the realm of telemedicine due to unexpected necessity. | 2020-05-16 |
| 32341519 | Timely analysis of the laboratory characteristics associated with 2019 novel coronavirus pneumonia (COVID-19) can assist with clinical diagnosis and prognosis. | 2020-05-08 |
| 32341718 | But for Hubei Province, the subjects of Wuhan City and Hubei Province were included from the time of admission to the Huoshenshan Hospital to present day in order to ensure that all or the majority of the confirmed and suspected patients were collected for diagnosis and treatment. | 2020-05-16 |
| 32341721 | The median time from admission to diagnosis of SARS-Cov-2 infection was 34 days (5-61 days). […] In 12 patients (80%), the diagnosis was made after a hospital stay of more than 14 days (15-63 days). | 2020-04-28 |
| 32341722 | In some doubtful cases, virologic assessment of stool samples can yield definitive diagnosis. | 2020-04-28 |
| 32341946 | In the bioinformatics area, one of the crucial points is the analysis of the virus nucleotide sequences using approaches such as data stream, digital signal processing, and machine learning techniques and algorithms. | 2020-05-21 |
| 32342051 | Even though we need to be vigilant in the diagnosis of COVID-19, we should not forget about the common pathologies. | 2020-04-28 |
| 32342174 | A survey among all 36 University Pathologies was conducted (return rate 83%) and evaluated; it allows to assess the current situation and shows significant restrictions in the diagnostic and research performance and high willingness to perform Coviid autopsies. | 2020-04-29 |
| 32342191 | To illustrate the [18F]FDG-PET/CT findings in patients affected by cancer with clinical diagnosis of Covid-19 METHODS: We retrospectively reviewed the cases of patients who showed pulmonary involvement unrelated to cancer metastases on March 13 and 16 2020. | 2020-05-28 |
| 32342543 | Operative diagnosis and procedure; droplet count and distribution on face shields were documented. | 2020-05-29 |
| 32342566 | Otolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of ageusia and nonspecific anosmia that arose suddenly and are not associated with rhinitis symptoms. | 2020-05-29 |
| 32342570 | We performed a literature review of current evidence surrounding SARS-CoV-2 diagnostic testing highlighting its utility, limitations, and implications for otolaryngologists. | 2020-05-12 |
| 32342849 | This case demonstrates that viral shedding after COVID-19 diagnosis can be prolonged. | 2020-04-28 |
| 32342927 | Diagnosis of suspected cases is confirmed by nucleic acid assays with real-time PCR, using respiratory samples. […] A review of multiple reports and kit inserts on the diagnostic performance of rapid tests from various manufacturers that are commercially available were performed. […] There is much to determine regarding the value of serological testing in COVID-19 diagnosis and monitoring. | 2020-04-30 |
| 32342928 | Routine nasopharyngeal swab of suspected COVID-19 infection should take anatomy of the nasal cavity into consideration to increase patient comfort and diagnostic yield. […] Routine oropharyngeal swab should be replaced by throat washing which has demonstrated better diagnostic accuracy, and it is safe towards others. | 2020-04-30 |
| 32343300 | As an aerosol-generating procedure, traditional pediatric microlaryngoscopy and bronchoscopy techniques must be adapted in order to reduce the risk of transmission of severe acute respiratory syndrome coronavirus 2. […] The main outcome was the feasibility of technique, which was measured by ability to perform microlaryngoscopy and bronchoscopy with comparable success to the usual technique (ie, adequate examination of the patient for diagnostic procedures and ability to perform interventional procedures). | 2020-05-05 |
| 32343968 | We report two cases of patients who received a diagnosis of COVID-19 complicated by CRS and were treated with tocilizumab. | 2020-05-06 |
| 32344166 | We describe the virological characteristics of SARS-CoV-2 and the clinical course of COVID-19 with an emphasis on diagnostic challenges, duration of viral shedding, severity markers and current treatment options. […] However, accurate diagnosis as well as early identification and management of high-risk severe cases are important for many clinicians. | 2020-05-22 |
| 32344309 | In the ongoing process, radiological imaging is also preferred where chest X-rays are highlighted in the diagnosis. […] The SqueezeNet that comes forward with its light network design is tuned for the COVID-19 diagnosis with Bayesian optimization additive. […] Fine-tuned hyperparameters and augmented dataset make the proposed network perform much better than existing network designs and to obtain a higher COVID-19 diagnosis accuracy. | 2020-05-18 |
| 32344317 | Moreover, the COVID-19 manifestations as well as its diagnosis are particular in this special population. | 2020-05-28 |
| 32344370 | The available technologies of Industry 4.0 could also help the detection and diagnosis of COVID-19 and other related problems and symptoms. | 2020-05-27 |
| 32344438 | Nearly all participants (97 %) report a decline of nuclear medicine diagnostic procedures. | 2020-04-28 |
| 32344568 | Testing for the presence of coronavirus is an essential diagnostic tool for monitoring and managing the current COVID-19 pandemic. | 2020-05-01 |
| 32345226 | Combining chest computed tomography images with the qPCR analysis of throat swab samples can improve the accuracy of COVID-19 diagnosis. | 2020-04-30 |
| 32345443 | In view of the current pandemic by SARS-CoV-2 it deems essential to understand the key concepts about the infection: its epidemiological origin, presentation, clinical course, diagnosis and treatment (still experimental in many cases). | 2020-05-01 |
| 32345728 | We searched MEDLINE/PubMed, CINAHL (EBSCO), and Scopus databases for adult patients with preexisting neurologic disease who were diagnosed and hospitalized for COVID-19 or reported incidence of secondary neurologic events following diagnosis of COVID-19. | 2020-05-29 |
| 32346223 | In the meantime, extensive gathering of diagnostic data on who is infectious will be essential to save lives, train AI, and limit economic damages. | 2020-05-01 |
| 32346392 | This paper discusses the impact of coronavirus infection on cancer diagnosis and treatment in two leading cancer centres in Pakistan. […] There is an urgent need to evaluate the effect of delays in diagnosis and treatment on cancer stage and treatment, and to decide how to minimise these during likely future cycles of lockdown over the coming months and years. | 2020-05-01 |
| 32346593 | While CT examination serves as the screening and diagnostic basis for COVID-19, its accuracy is limited. […] The nucleic acid testing is the gold standard for the diagnosis of COVID-19, but has a low sensitivity is low. […] This paper reviews the published literature, guidelines and consensus, and summarizes the clinical and imaging characteristics of COVID-19, in order to provide a reliable basis for early diagnosis and treatment. | 2020-05-11 |
| 32346790 | We updated our published systematic review on imaging findings in COVID-19 to include 37 published studies pertaining to diagnostic features of COVID-19 in chest CT. […] The proposed COVID-RADS and common lexicon would improve the communication of findings to other healthcare providers, thus facilitating the diagnosis and management of COVID-19 patients. […] • The proposed COVID-RADS and common lexicon would improve the communication of findings to other healthcare providers, thus facilitating the diagnosis and management of COVID-19 patients. | 2020-05-06 |
| 32346843 | Here, we raise the importance of stringent diagnosis and data collection regarding neurological complications of COVID-19; we urge caution in the over-diagnosis of neurological disease where it does not exist, but equally strongly encourage the concerted surveillance for such conditions. | 2020-05-01 |
| 32346873 | The median time from exposure to diagnosis was 7.0 days (interquartile range [IQR]: 1.0-15.0 days). | 2020-05-13 |
| 32347053 | Since SARS-CoV-2 and SARS-CoV are closely related, previous findings on SARS-CoV are highly relevant to a better understanding as well as diagnosis, treatment, prevention and control of SARS-CoV-2. […] In this review, we highlight recent progresses in the field; compare the biological characteristics of SARS-CoV and SARS-CoV-2; summarize the urgently-needed diagnostic, treatment, prevention and control options; and provide future perspectives for the outcome of the outbreak and research questions to be answered, including some of the difficulties in vaccine development. | 2020-05-01 |
| 32347067 | Therefore, the optimized assay developed in this study can be used in screening and early clinical diagnosis. […] Our work provides a tool to facilitate rapid clinical diagnosis of COVID-19. | 2020-05-01 |
| 32347112 | The coronavirus disease 2019 (COVID-19) pandemic during the first months of 2020 is causing profound changes in worldwide health care systems, resulting in a major reduction of surgical interventions and routine non-urgent outpatient diagnostic procedures. […] Furthermore, as the current measures of lockdown continue, it will be difficult to perform scheduled and new diagnostic assessments, medical treatments and surgical procedures in a timely manner favoring the risk of diagnostic and therapeutic delays with severe impact on patients’ health. | 2020-04-29 |
| 32347200 | While our models would not justify presumptive SARS-CoV-2 diagnosis without molecular confirmation, it can contribute to targeted screening strategies. | 2020-05-01 |
| 32347618 | Their age, sex, diagnosis of disease, requirement for emergent intervention, and their medical records about COVID-19 were obtained. | 2020-05-22 |
| 32347761 | For the dermatology community, this interruption to the healthcare system can lead to delays in the diagnosis and treatment of melanoma. | 2020-05-13 |
| 32347772 | Identified strategies included early recognition of the threat and rapid activation of national response protocols led by national leadership; rapid establishment of diagnostic capacity; scale-up of measures for preventing community transmission; and redesigning the triage and treatment systems, mobilizing the necessary resources for clinical care. […] Key recommendations include (1) recognize the problem, (2) establish diagnostic capacity, (3) implement aggressive measures to prevent community transmission, (4) redesign and reallocate clinical resources for the new environment, and (5) work to limit economic impact through and while prioritizing controlling the spread and impact of COVID-19. | 2020-05-04 |
| 32347964 | The aim of this review is to demonstrate the potential utility of enhanced DNA-based stool testing for colorectal cancer screening and diagnosis during crises that strain available healthcare resources, such as the current COVID-19 pandemic. | 2020-05-29 |
| 32348233 | These patients later showed development of persistent hypoxia with increased levels of d-dimer levels and were given a diagnosis of pulmonary embolisms. | 2020-04-29 |
| 32348339 | They were tested for HFABP after the diagnosis of COVID-19, and monitored for HFABP during their hospital stay. | 2020-05-04 |
| 32348585 | Imaging modalities such as chest radiography, thoracic and cardiovascular ultrasound, and computed tomography have roles in the diagnosis, prognosis, monitoring, and therapy of COVID-19. | 2020-04-29 |
| 32348588 | Real-time PCR is used as a diagnostic tool using nasal swab, tracheal aspirate or bronchoalveolar lavage samples. […] Computed tomography findings are important for both diagnosis and follow-up. | 2020-05-13 |
| 32349032 | The stringent medical resources hinder the diagnostic capacity globally, while 84 thousands of new cases confirmed within a single day of 14 April 2020. […] Real-time reverse-transcriptase polymerase chain reaction (RT-PCR) with is the current first-line diagnosis, but the false-negative rate remains concerned. […] Radiographic technologies and tools, including Computed tomography (CT) and Chest X-ray (CXR), were applied for initial screening and follow-up, from which provides detail diagnosis with specific pathologic features for staging and treatment arrangement. […] In this review, we will discuss the challenges and the future perspectives of using radiographic modalities for COVID-19 diagnosis in view of securing human lives amid the crisis. | 2020-04-29 |
| 32349033 | These platforms can facilitate routine diagnostic assays in certified clinical labs. | 2020-04-29 |
| 32349121 | To enable routine surveillance and comprehensive diagnostic applications, there is a need for detection technologies that can scale to test many samples1-3 while simultaneously testing for many pathogens4-6. […] Scalable, highly multiplexed CRISPR-based nucleic acid detection shifts diagnostic and surveillance efforts from targeted testing of high-priority samples to comprehensive testing of large sample sets, greatly benefiting patients and public health9-11. | 2020-05-28 |
| 32349382 | Although we have covered many topics related to health monitoring using IR-UWB, this paper is mainly focused on signal processing techniques for measurement of vital signs, i.e., respiration and heart rate monitoring. | 2020-05-01 |
| 32349902 | Efforts should be made to provide the best evidence-based care, which will mean revisiting old techniques, and risk stratifying patients on a case by case basis. | 2020-05-02 |
| 32350047 | The absence of FDA oversight of serologic tests is concerning, given that the commercially available serologic assays are highly variable, differing in their format, the antibody class detected, the targeted antigen and the acceptable specimen types. | 2020-04-30 |
| 32350048 | Multiple laboratory developed tests and commercially available assays have emerged to meet diagnostic needs related to the SARS-CoV-2 pandemic. | 2020-04-30 |
| 32350226 | We recently reported a laboratory diagnostic protocol for SARS-CoV-2 based on real-time RT-PCR assays using two primer sets, N and N2. […] On 30-31 January 2020, the protocol and reagents for these assays were distributed to local public health institutes and quarantine depots in Japan, and nationwide, SARS-CoV-2 diagnostic testing was started. […] These indicate that the protocol using the N and N2 sets is comparable to commercially available kits and is reliable for the laboratory diagnosis of COVID-19. | 2020-04-30 |
| 32350462 | Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections. | 2020-04-30 |
| 32350794 | Italian radiology departments found themselves at the forefront in the management of suspected and positive COVID cases, both in diagnosis, in estimating the severity of the disease and in follow-up. […] In this emergency situation, several expectations have been raised by the scientific community about the role that artificial intelligence can have in improving the diagnosis and treatment of coronavirus infection, and SIRM wishes to deliver clear statements to the radiological community, on the usefulness of artificial intelligence as a radiological decision support system in COVID-19 positive patients. […] (3) Chest CT with artificial intelligence cannot replace molecular diagnosis tests with nose-pharyngeal swab (rRT-PCR) in suspected for COVID-19 patients. | 2020-05-13 |
| 32350796 | Radiological imaging plays a key role in the diagnostic process and during the monitoring of the clinical conditions especially of patients with severe symptoms. | 2020-05-13 |
| 32350871 | A retrospective analysis of medical records and comparison of vaginal delivery outcomes between 10 pregnant women with clinical diagnosis of COVID-19 and 53 pregnant women without COVID-19 admitted to Zhongnan Hospital of Wuhan University between January 20 and March 2, 2020. […] Results of laboratory tests, imaging tests, and SARS-CoV-2 nucleic acid tests were also analyzed in neonates delivered by pregnant women with clinical diagnosis of COVID-19. […] Neonates delivered by pregnant women with clinical diagnosis of COVID-19 tested negative for SARS-CoV-2 infection. | 2020-05-19 |
| 32351037 | Time intervals from onset to visit, hospitalization and diagnosis confirmed were all shortened after Shanghai’s first-level public health emergency response. | 2020-05-13 |
| 32351103 | In the diagnosis of COVID-19, the polymerase chain reaction (RT-PCR) is considered as the reference standard test. […] In the early stages, thorax CT findings could be present even before the onset of symptoms, thorax CT has quite high sensitivity in COVID-19 patients with false negative RT-PCR results, and it has a great importance not only in diagnosis but also in follow up (6,7). […] We think that it might be beneficial for our radiologist colleagues in the early diagnosis of the imaging features of this disease, by sharing the experiences we have gained by evaluating the typical and relatively atypical CT findings regarding the natural course of the tomographic findings of COVID-19 and when to control CT. | 2020-04-30 |
| 32351814 | Given the highly infectious nature of the coronavirus disease 2019 (COVID-19) virus and the lack of proven specific therapeutic drugs and licensed vaccines effective against it, early diagnosis of the disease is of paramount importance. | 2020-04-30 |
| 32351851 | Early diagnosis and self-isolation or quarantine remain key to stemming the tide of the contagion as there is a real risk of the healthcare system being overwhelmed. | 2020-05-05 |
| 32352202 | Patients with positive diagnosis of Covid-19 were recruited from 18 European hospitals. | 2020-04-30 |
| 32352309 | OBJECTIVE. Because CT plays an important role in diagnosis, isolation, treatment, and effective evaluation of coronavirus disease (COVID-19), infection prevention and control management of CT examination rooms is important. CONCLUSION. We describe modifications to the CT examination process, strict disinfection of examination rooms, arrangement of waiting areas, and efforts to increase radiographers’ awareness of personal protection made at our institution during the COVID-19 outbreak. | 2020-04-30 |
| 32352915 | Proactive measures, therefore, must be taken to ensure the continuation of diagnostic and interventional support to clinicians, while minimizing the risk of nosocomial transmission among staff and other patients. | 2020-04-30 |
| 32352917 | A fast and accurate diagnosis in this outbreak is critical to isolate and treat patients. […] Radiology plays an important role in the diagnosis and management of the patients. […] Shortcomings of the real-time reverse transcriptase-polymerase chain reaction test, including inappropriate sample collection and analysis methods, initial false negative results, and limited availability has led to widespread use of chest CT in the diagnostic algorithm. […] This review summarizes the role of radiology in COVID-19 pneumonia, diagnostic accuracy of imaging, and chest CT findings of the disease. | 2020-04-30 |
| 32352933 | The positive result of nucleic acid test is a golden criterion to confirm SARS-CoV-2 infection, but the detection features remain unclear.METHODSWe performed a retrospective analysis in 5630 high-risk individuals receiving SARS-CoV-2 nucleic acid tests in Wuhan, China, and investigated their characteristics and diagnosis rates.RESULTSThe overall diagnosis rate was 34.7% (1952/5630). […] Furthermore, we investigated the association between diagnosis rate and the amount of testing in 501 subjects. […] Results revealed a 1.27-fold improvement (from 27.9% to 35.5%) of diagnosis rate from testing once to twice (P = 5.847 × 10-9) and a 1.43-fold improvement (from 27.9% to 39.9%) from testing once to 3 times (P = 7.797 × 10-14). […] Increasing the amount of testing could significantly improve diagnosis rates, except for subjects with pneumonia. | 2020-05-25 |
| 32353184 | Univariate analyses associated both diagnosis of drug-resistant epilepsy and time spent paying attention to COVID-19 with severe psychological distress (defined as K-6 score >12; both P ≤ .001). […] Multivariate logistic regression identified two independent predictors of severe psychological distress: time spent paying attention to COVID-19 (odds ratio [OR] = 1.172, 95% confidence interval [CI] = 1.073-1.280) and diagnosis of drug-resistant epilepsy (OR = 0.283, 95% CI = 0.128-0.623). | 2020-05-22 |
| 32353457 | Further studies testing UVGI and other decontamination techniques are an unmet need. | 2020-05-30 |
| 32353518 | More than one-third of psychiatric patients might fulfil the diagnostic criteria post-traumatic stress disorder (PTSD). | 2020-05-03 |
| 32353547 | Provision of quarantine or isolation facilities and availability of rapid diagnostic kits for fast and reliable testing and diagnosis of the disease can also be a challenge in Africa. | 2020-05-29 |
| 32353746 | The high number of arterial and, in particular, venous thromboembolic events diagnosed within 24 h of admission and the high rate of positive VTE imaging tests among the few COVID-19 patients tested suggest that there is an urgent need to improve specific VTE diagnostic strategies and investigate the efficacy and safety of thromboprophylaxis in ambulatory COVID-19 patients. | 2020-05-30 |
| 32353760 | Numerous nucleic acid amplification assays have recently received emergency use authorization (EUA) for the diagnosis of SARS-CoV-2 infection, and there is a need to assess their test performance relative to one another. […] We performed a diagnostic comparison study by testing nasopharyngeal samples on the two assays. | 2020-05-27 |
| 32353762 | From February 19, 2020 to April 15, 2020, 12870 patients referred to the hospital emergency department, of which 2968 were hospitalized with COVID-19 diagnosis. | 2020-05-27 |
| 32353825 | The key step to infection prevention is to identify risk points of infection exposure, strengthen the protection against those risk points, and formulate an appropriate diagnosis and treatment protocol. […] Following an in-depth study of the latest literature on COVID-19 diagnosis and treatment, we reviewed the protocols surrounding hospitalization of patients with extensive burns (area≥50 %) in our hospital from February 2009 to February 2019 and, in accordance with the epidemiological characteristics of COVID-19, developed an algorithm for protection during diagnosis and treatment of burns. […] Therefore, the aspects of medical protection and the diagnosis and treatment of burns appear to be particularly important during the prevention and control of the COVID-19. | 2020-05-21 |
| 32353857 | Diagnostic testing is critical for epidemiological surveillance, but the accuracy (sensitivity and specificity) and clinical utility (impact on health outcomes) of the current diagnostic methods used for SARS-CoV-2 detection are not known. […] I ran a quick search in PubMed/MEDLINE to find studies on laboratory diagnostic tests and rapid viral diagnosis. | 2020-05-04 |
| 32354113 | The applications of nanochemistry and general nanotechnology was also discussed to give the status of nanodiagnostic systems for COVID-19. | 2020-05-01 |
| 32354369 | Nucleic acid detection is considered as the gold standard for the diagnosis of COVID-19. […] This case report described an effective supportive medication scheme to treat SARS-COV-2 infected patient and emphasized the necessity of detection of the viral genome using BALF samples and its significance in the diagnosis and prognosis of the disease. | 2020-05-04 |
| 32354651 | Hospitalization should be reserved for emergencies, the conduct of treatments that cannot be postponed, check-ups for which the diagnostic delay may result in a loss of survival chance, and cardiorespiratory assessments for which the delay could be detrimental to the patient. | 2020-05-03 |
| 32354990 | This Italian prospective observational cohort study enrolled consecutive patients with an established IBD diagnosis and confirmed COVID-19. […] Age over 65 years (p=0.03), UC diagnosis (p=0.03), IBD activity (p=0.003) and a CCI score >1 (p=0.04) were significantly associated with COVID-19 pneumonia, whereas concomitant IBD treatments were not. | 2020-05-28 |
| 32355546 | At present, diagnosis COVID-19 were based on real-time RT-PCR, which have to be performed in biosafe laboratory and is unsatisfactory for suspect case screening. […] Therefore, there is an urgent need for rapid diagnostic test for COVID-19. […] To evaluate the diagnostic performance and clinical utility of the colloidal gold immunochromatography assay for SARS-Cov-2 specific IgM/IgG anti-body detection in suspected COVID-19 cases. […] At least two samples of each patient were collected for RT-PCR assay analysis, and the PCR results were performed as the reference standard of diagnosis. […] The colloidal gold immunochromatography assay for SARS-Cov-2 specific IgM/IgG anti-body had 71.1% sensitivity and 96.2% specificity in this population, showing the potential for a useful rapid diagnosis test for COVID-19. | 2020-05-03 |
| 32355837 | Herein, we aim to discuss the latest updates on the origin, genomic characteristics, diagnosis, treatment options and current efforts being made by international health organizations with regards to the 2019-nCoV outbreak. | 2020-05-05 |
| 32356508 | Immediate RP was defined as RP within 3-months of diagnosis, while delayed RP was analyzed in 3-month intervals up to 12-months. | 2020-05-01 |
| 32356641 | Gastroenterologists and members of other medical specialties should also remember that the current epidemiological situation has changed diagnostic and therapeutic algorithms in the management of several gastrointestinal and liver disorders. | 2020-05-29 |
| 32356672 | COVID-19 - More Lung Pocus and Sparing Use of Stethoscope, Chest X-Ray and Lung CT Abstract. For an optimal management of COVID-19 (Coronary Virus Disease) we depend on a fast and reliable diagnosis and severity assessment. […] Moreover, all three diagnostic examination techniques expose physicians, support staff and subsequent patients to an additional risk of exposure. | 2020-05-01 |
| 32356760 | Lung infection or pneumonia is the common complication of COVID-19, and imaging techniques, especially computed tomography (CT), have played an important role in diagnosis and treatment assessment of the disease. | 2020-05-01 |
| 32357257 | This review discusses respirators, their purpose, types, clinical efficiency and proper donning and doffing techniques. | 2020-05-29 |
| 32357288 | In both scenarios, the “fertility window” may be transitory; postponing diagnostic semen analysis and sperm banking in these men could compromise the prospects of biological parenthood. | 2020-05-23 |
| 32357381 | A plethora of respiratory sampling methods for SARS-CoV-2 viral detection has been used and in the current evolving situation, there is no international consensus on the recommended method of respiratory sampling for diagnosis. | 2020-05-08 |
| 32357503 | The current outbreak of COVID-19 severe respiratory disease, which started in Wuhan, China, is an ongoing challenge, and a major threat to public health that requires surveillance, prompt diagnosis, and research efforts to understand this emergent pathogen and to develop an effective response. […] Due to the scientific community’s efforts, there is an increasing body of published studies describing the virus’ biology, its transmission and diagnosis, its clinical features, its radiological findings, and the development of candidate therapeutics and vaccines. […] Selective approaches to postmortem diagnosis, such as limited postmortem sampling over full autopsy, can also be useful in the control of disease outbreaks and provide valuable knowledge for managing appropriate control measures. | 2020-05-04 |
| 32357575 | There is an urgent need to share expertise and clinical management skills with geriatricians as well as the need for early diagnosis to start treatment at the earliest convenience in the community, with the aim to avoid the collapse of intensive care units. | 2020-05-04 |
| 32357808 | Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. | 2020-05-14 |
| 32357994 | A total of 218 COVID-19 positive patients from March 18th-April 8th, 2020 with a malignant diagnosis were identified. | 2020-05-06 |
| 32358689 | Although chest X-ray (CXR) is considered not sensitive for the detection of pulmonary involvement in the early stage of the disease, we believe that, in the current emergency setting, CXR can be a useful diagnostic tool for monitoring the rapid progression of lung abnormalities in infected patients, particularly in intensive care units. | 2020-05-13 |
| 32358691 | To improve the risk stratification of patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an experimental chest X-ray (CXR) scoring system for quantifying lung abnormalities was introduced in our Diagnostic Imaging Department. | 2020-05-13 |
| 32358855 | Operative diagnosis; droplet count and distribution on plastic sheet and face shields were documented. | 2020-05-06 |
| 32358956 | Our results indicate that serological tests could be powerful approach for the early diagnosis of COVID-19. | 2020-05-06 |
| 32358960 | Though diagnostic tests are fundamental to the ability to detect and respond, overwhelmed healthcare systems are already experiencing shortages of reagents associated with this test, calling for a lean immediately-applicable protocol. | 2020-05-06 |
| 32359201 | This “quantitative and time-sequence dependent” model has several implications for prevention, diagnosis, and therapy of COVID-19 at all ages. | 2020-05-02 |
| 32359210 | We also highlight the role of lung ultrasonography in early diagnosis of the inflammatory phase of COVID-19. | 2020-05-02 |
| 32359223 | With the ongoing need for urgent and emergency colorectal surgery, including surgery for colorectal cancer, several questions pertaining to operating room (OR) utilization and techniques needed to be rapidly addressed. | 2020-05-22 |
| 32359226 | The novel coronavirus disease 2019 (COVID-19) pandemic has urged the development and implementation of guidelines and protocols on diagnosis, management, infection control strategies, and discharge planning. | 2020-05-02 |
| 32360053 | Body temperature was measured and acquired for each patient, a coronavirus disease 2019 (COVID-19) epidemiologic investigation questionnaire was given to each patient, an endodontic diagnosis was determined for the offending tooth, and a verbal numerical rating scale (VNRS) was used to record pain levels. | 2020-05-26 |
| 32360111 | We report our experience on lung ultrasound examination in the diagnosis of Sars-Cov-2 pneumonia in a pregnant woman. […] We suggest point of care lung ultrasound examination as a diagnostic imaging tool in pregnant women with suspected COVID-19. | 2020-05-05 |
| 32360205 | In some doubtful cases, virologic assessment of stool samples can yield definitive diagnosis. | 2020-05-05 |
| 32360420 | Guidelines for the diagnosis and treatment of SARS-CoV-2 infected pneumonia were first published January 30th, 2020; these guidelines recommended for the first time that cytokine monitoring should be applied in severely ill patients to reduce pneumonia related mortality. | 2020-05-13 |
| 32360479 | To analyze the diagnosis and treatment of patients with chronic renal failure complicated with novel coronavirus pneumonia, and to evaluate the effect of blood purification technology on the treatment and prognosis of such patients. | 2020-05-11 |
| 32360481 | Of the patients, 67.1 % were originally healthy people with no underlying diseases, others mostly had common comorbidities including hypertension (12.3 %) and diabetes (5.5 %), 10.9 % were current smokers, 30.1 % had low white blood cell counts and 45.2 % showed decreased lymphocytes at the first time of diagnosis. […] The epidemiological characteristics of patients in the area around Wuhan, such as Shiyan, at first diagnosis are described as follows: Patients had histories of Wuhan residences in the early stage and family clustering in the later period. […] The initial diagnosis of the patients was mostly ordinary, and the percentage of critical patients who evolved into the ICU during follow-up is 2.7 %, which is lower than the 26.1 % reported by Wuhan city. […] According to the Shiyan experience, early diagnosis with multiple swaps of the Q-PCR test and timely treatment can reduce the death rate. […] No evidence exists that smoking protects COVID-19 patients from developing to severe/critical cases, and the absolute number of lymphocytes at initial diagnosis could not predict the progression risk from severe to critical condition. | 2020-05-30 |
| 32360679 | All 20 patients already had a diagnosis of COVID-19 pneumonia. | 2020-05-15 |
| 32360780 | Diagnosis of COVID-19 was confirmed by real-time RT-PCR. | 2020-05-29 |
| 32360862 | Review of the current telehealth landscape including usage, policies, and techniques for ambulatory practice integration. | 2020-05-06 |
| 32361161 | In this paper, we will systematically review the pathogenic features, transmission routes, and infection mechanisms of SARS-CoV-2, as well as any adverse effects on the digestive system, urogenital system, central nervous system, and circulatory system, in order to provide a theoretical and clinical basis for the diagnosis, classification, treatment, and prognosis assessment of SARS-CoV-2 infection. | 2020-05-21 |
| 32361285 | The rapid spread of the virus challenged diagnostic laboratories to rapidly develop molecular diagnostic methods. […] As SARS CoV-2 assays became available for testing on existing molecular platforms, laboratories devoted unprecedented energy and resources into evaluating the analytical performance of the new tests and in some cases developed their own diagnostic assays under FDA-EUA guidance. | 2020-05-27 |
| 32361529 | Many nations are employing combinations of containment and mitigation strategies, where early diagnosis of COVID-19 is vital in controlling illness progression and limiting viral spread within the population. […] These requirements coupled with associated financial pressures may prevent effective deployment of such diagnostic tests. […] We hypothesise that recent advancements in enhanced LAMP protocols assay perhaps represent the best chance for a rapid and robust assay for field diagnosis of COVID-19, without the requirement of specialized equipment and highly trained professionals to interpret results. […] We hope that this strategy could be applied rapidly, and confirmed for viability with clinical samples, before being rolled out for mass-diagnostic testing in these current times. | 2020-05-12 |
| 32361714 | There have already been papers on the radiology preparedness that should be applied to radiology and nuclear medicine departments to support the care of patients with COVID-19 and maintain radiologic diagnostic and interventional support for the entirety of the hospital and healthcare system, particularly for emergencies, without jeopardizing an outbreak in the units. […] Since most nuclear medicine diagnostic and therapeutic interventions are non-urgent, the general guidance from the International Atomic Energy Agency (IAEA) for infection prevention and control is to postpone scheduled procedure after cautious risk assessment, with certain exceptions. | 2020-05-05 |
| 32362005 | Bioinformatics techniques such as artificial intelligence should be used for collecting the hemogram and serum biochemistry data of all COVID-19- infected people worldwide, even they do not show severe symptoms. […] These data may help find a biomarker that can be used in combination with the CT results for rapid and accurate diagnosis of COVID-19. | 2020-05-21 |
| 32362041 | Uncertainty about the duration of these measures led us to consider the potential impact of diagnostic delays due to the paralyzation of certain health procedures and services on the prognosis of patients with melanoma. | 2020-05-03 |
| 32362296 | The diagnosis of COVID-19 was based on positive COVID-19 nucleic acid testing according to the unified triage standards of the Guidelines for the Diagnosis and Treatment of Novel Coronavirus Pneumonia (Trial version 4),4 issued by the National Health Commission of the People’s Republic of China. | 2020-05-20 |
| 32362344 | The COVID-19 diagnostic standard was polymerase chain reaction detection of target genes of 2019 novel coronavirus (2019-nCoV). | 2020-05-06 |
| 32362384 | This consensus document has been drawn up by the Techniques and Transplantation and Nursing areas of the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) and the Spanish Society of Respiratory Endoscopy (AEER) with the aim of providing information on the safe and effective use of bronchoscopy in patients with suspected or confirmed COVID-19 infection. | 2020-05-16 |
| 32362424 | This narrative literature review aims to gather the main contributions in the area of intensive care to date in relation to the epidemiology, clinic, diagnosis and management of 2019-nCoViD. | 2020-05-04 |
| 32362647 | Data were extracted from Virus Research and Diagnostic Laboratory Network for analysis. | 2020-05-06 |
| 32362799 | Instead of applying simplistic and uniform assumptions for a MC which is a common practice, a deep learning-based CMC is used in conjunction of fuzzy rule induction techniques. | 2020-05-07 |
| 32362969 | The main aim of this systematic review is to provide a comprehensive clinical summary of all the available data from high-quality research articles relevant to the epidemiology, demographics, trends in hospitalization and outcomes, clinical signs and symptoms, diagnostic methods and treatment methods of COVID-19, thus increasing awareness in health care providers. | 2020-05-07 |
| 32363045 | Based on the current epidemic situation, this study reviewed publications on this virus and coronavirus disease 2019 (COVID-19), analyzed common features of respiratory viral pneumonias, and presented the currently reported clinical characteristics of COVID-19 in transplant recipients to improve strategies regarding the diagnosis and treatment of COVID-19 in this special population. | 2020-05-07 |
| 32363205 | The diagnostic evaluation process of suspected patients needs to be accelerated at the epicentre of the outbreak and early isolation of infected patients in a healthcare setting rather than at home is urgently required to stop the spread of the virus. | 2020-05-07 |
| 32363337 | We present a case of rapid clinical decompensation and development of severe Acute Respiratory Distress Syndrome (ARDS) in a woman at 31 weeks’ gestation to highlight these unique considerations and present an algorithmic approach to the disease’s diagnosis and management. | 2020-05-04 |
| 32363809 | A model using all 5 diagnostic symptoms had the highest accuracy with a predictive ability of 82% in discriminating between COVID-19 results. […] To maximize sensitivity and maintain fair diagnostic accuracy, a combination of 2 symptoms, change in sense of smell or taste and fever was found to have a sensitivity of 70% and overall discrimination accuracy of 75%. | 2020-05-04 |
| 32364028 | Of these, 47 were hospitalized, 53 needed a differential diagnosis to continue with their cancer treatment, and 201 were about to undergo surgery. | 2020-05-04 |
| 32364358 | These results strongly support that Anhui and Clungene rapid tests detecting IgM and IgG antibodies against SARS-CoV-2 virus should not be used in the differential diagnosis of infection. | 2020-05-06 |
| 32364528 | Evaluating chest CT, clinical symptoms, and laboratory results could facilitate the early diagnosis of COVID-19, and judge disease progression. | 2020-05-26 |
| 32364936 | Electrochemical biosensors for pathogen detection are broadly reviewed in terms of transduction elements, biorecognition elements, electrochemical techniques, and biosensor performance. | 2020-05-06 |
| 32364959 | The diagnostic value of CT is unclear. […] No statistical difference was found in the diagnostic performance between initial RT-PCR and chest CT. […] Initial RT-PCR and chest CT had comparable diagnostic performance in identification of suspected COVID-19 patients outside the epidemic center. | 2020-05-29 |
| 32364962 | There are several specific image changes along with the disease progression may be helpful in early recognition and differential diagnosis of Coronavirus Disease 2019. | 2020-05-29 |
| 32365415 | For patients with severe aortic stenosis, efforts to bring treatment to symptomatic patients amid this pandemic might lead to favored use of catheter based management using minimalist techniques that do not require these elements. | 2020-05-04 |
| 32365567 | The techniques mentioned herein have already had significant impacts in our lives, from in-the-field diagnosis of disease and parasitic infections, through home fertility tests, to uncovering the interactions between SARS-CoV-2 and their host cells. […] How do these techniques work? | 2020-05-05 |
| 32365891 | As this was a current study, there are still not many sources in the literature, and scientific strategies are moving towards therapy and diagnosis, rather than knowing the characteristics of the virus. | 2020-05-08 |
| 32366131 | A Literature search was performed using PubMed [1 December 2019-17 April 2020].Expert opinion: This paper reviews the remarkable diagnostic and therapeutic potential of the CRISPR-Cas9 platform and concludes with a look at ethical issues and technical hurdles pertaining to the implementation of permanent gene modification in the practice of Hospital Medicine. | 2020-05-14 |
| 32366162 | This “digital divide” is not fair to our patients in need-especially those with a cancer diagnosis. | 2020-05-05 |
| 32366746 | This article summarized the understanding of the etiology, pathogenesis, epidemiology, clinical characteristics, diagnosis, treatment, rehabilitation, and prevention and control measures of COVID-19 based on the available data and anti-epidemic experience in China. | 2020-05-05 |
| 32366759 | In fighting COVID-19, radiologic examinations played a critical role in the early diagnosis of COVID-19, and could also help assess disease course and severity. | 2020-05-05 |
| 32367319 | Artificial intelligence (AI) software has been employed to facilitate CT diagnosis. […] In this communication, we present an example of a good tool for the radiologist (Thoracic VCAR software, GE Healthcare, Italy) in Covid-19 diagnosis (Pan et al. in Radiology, 2020. https://doi.org/10.1148/radiol.2020200370). […] Therefore, keeping in mind that CT has high diagnostic sensitivity in identifying lesions, but not specific for Covid-19 and similar to other infectious viral diseases, it is mandatory to have an AI software that expresses objective evaluations of the percentage of ventilated lung parenchyma compared to the affected one. | 2020-05-13 |
| 32367615 | Fast and widespread diagnosis is crucial to fighting against the outbreak of COVID-19. […] Molecular diagnostic assays based on quantitative reverse transcription polymerase chain reaction are used in most clinical laboratories. | 2020-05-27 |
| 32367683 | There was a reduction in daily emergency room attendance since January 25, 2020 (group 1,327/day vs. group 2,231/day) and 149 patients with diagnosis of MI were included into analysis (group 1 N = 85 vs. group 2 N = 64). | 2020-05-05 |
| 32367749 | This case emphasized the importance of peripheral blood smear and clinical manifestation, especially in the differential diagnosis of thrombocytopenia. | 2020-05-14 |
| 32367888 | CONCLUSIONS The dynamic changes of CT images of lungs of COVID-19 patients, combined with the clinical manifestations and laboratory indicators of patients, can help guide clinical diagnosis and treatment. | 2020-05-06 |
| 32368493 | The case represents the importance of prompt diagnosis and awareness of the potential co-infection with other respiratory viruses and this novel deadly virus. | 2020-05-08 |
| 32368531 | These patients may also present with less well-defined symptoms like diarrhea, nausea, vomiting and/or abdominal discomfort both at the time of diagnosis and during the clinical course. | 2020-05-08 |
| 32368550 | Differential diagnosis of lung contusion and COVID-19 must be emphasized. | 2020-05-08 |
| 32368570 | The present study review is on the general continent, virology, pathogenesis, global epidemiology, clinical presentation, diagnosis, treatment and control of COVID-19 with the reference to India. | 2020-05-07 |
| 32368728 | We compared the clinical features and laboratory findings of the two groups, and analyzed the diagnostic performance of several laboratory parameters in predicting SARS-CoV-2 infection and made relevant comparisons to the China diagnosis guideline of having a normal or decreased number of leukocytes (≤9•5 109/L) or lymphopenia (<1•1 109/L). […] The addition of eosinopenia alone or the combination of eosinopenia and elevated hs-CRP into the guideline-recommended diagnostic parameters for COVID-19 improved the predictive capacity with higher than zero of both net reclassification improvement (NRI) and integrated discrimination improvement (IDI). | 2020-05-05 |
| 32368875 | After the lung computerized tomography (CT) findings which are important in the diagnosis of COVID-19 are described, protection measures against infection were defined in radiology departments. […] There is no publication involving protection measures for diagnostic and therapeutic procedures in nuclear medicine (NM) (appointment, patient acceptance, imaging and treatment procedures, disinfection etc). […] These lung findings detected in hybrid images will be helpful in the early diagnosis of pulmonary involvement. | 2020-05-14 |
| 32368928 | OBJECTIVE. The purpose of this study was to explore the value of CT in the diagnosis of coronavirus disease (COVID-19) pneumonia, especially for patients who have negative initial results of reverse transcription-polymerase chain reaction (RT-PCR) testing. MATERIALS AND METHODS. Patients with COVID-19 pneumonia from January 19, 2020, to February 20, 2020, were included. | 2020-05-05 |
| 32368994 | The reduction was visible for all diagnostic groups, except for a group of ‘Other’ diagnoses, which includes anxiety disorders, neurocognitive disorders, etc. | 2020-05-05 |
| 32369222 | The management of COVID-19 should focus on early diagnosis, immediate isolation, general and optimized supportive care, and infection prevention and control. | 2020-05-23 |
| 32369240 | The identification of C. auris necessitates use of sophisticated technology not readily available to make this essential diagnosis since C. auris is multi-drug resistant and isolation precautions would become paramount. | 2020-05-29 |
| 32369429 | Increased awareness of this fact may encourage earlier diagnosis and treatment, as well as heighten vigilance for viral transmission. | 2020-05-05 |
| 32369578 | Highly sensitive and specific nucleic acid amplification tests have become the diagnostic reference standard for viruses and translation of bacterial assays from basic research to routine clinical practice represents an exciting advance in respiratory medicine. […] Here, we summarize the current state of the art with respect to the diagnosis of viral and bacterial RTIs, provide a practical framework for diagnostic decision-making using selected patient-centered vignettes, and make recommendations for future studies to advance the field. | 2020-05-05 |
| 32369611 | The thoracic anaesthetic community has been confronted with the need to modify existing techniques to maximise safety for patients and healthcare professionals. | 2020-05-05 |
| 32369646 | Here, the World Endoscopy Organisation (WEO) is providing practical advice for the management of IBD patients during the pandemic covering the diagnostic and therapeutic spectrum. | 2020-05-05 |
| 32369666 | The observed risk for VTE in COVID-19 is high, particularly in ICU patients, which should lead to a high level of clinical suspicion and low threshold for diagnostic imaging for DVT or PE. […] Future research should focus on optimal diagnostic and prophylactic strategies to prevent VTE and potentially improve survival. | 2020-05-05 |
| 32369770 | Here, we summarize some of the diagnostic and management dilemmas for these patients, and we provide guidance on safe and as effective as possible delivery of care in the COVID-19 era. | 2020-05-07 |
| 32370128 | Diagnosis was confirmed either by DENV-specific real time reverse transcriptase polymerase chain reaction (rRT-PCR), or non-structural protein 1 (NS1) antigen or enzyme linked immunosorbent assay (ELISA) tests; a case fatality rate of 0.4% (10/3994) was observed. | 2020-05-06 |
| 32370204 | Thanks to the latest advancements in the field of molecular and computational techniques and information and communication technologies (ICTs), artificial intelligence (AI) and Big Data can help in handling the huge, unprecedented amount of data derived from public health surveillance, real-time epidemic outbreaks monitoring, trend now-casting/forecasting, regular situation briefing and updating from governmental institutions and organisms, and health facility utilization information. | 2020-05-11 |
| 32370561 | COVID-19 illuminates the need for a tiered diagnostic approach to rapidly identify clinically significant infections and reduce disease spread. […] A multi-tiered, diagnostic strategy incorporating a rapid host immune response assay as a screening test, molecular confirmatory testing and rapid IgM/IgG testing to assess benefit from quarantine/further testing and provide information on population exposure/herd immunity would efficiently evaluate potential COVID-19 patients. | 2020-05-21 |
| 32370983 | We quickly summarize the diagnostic and therapeutic approaches already in place, such as telemedicine, which is undergoing rapid development during the COVID-19 crisis. | 2020-05-08 |
| 32371057 | There is a massive international effort underway to develop diagnostic reagents, vaccines, and antiviral drugs in a bid to slow down the spread of the disease and save lives. […] One part of that international effort involves the research community working with plants, bringing researchers from all over the world together with commercial enterprises to achieve the rapid supply of protein antigens and antibodies for diagnostic kits, and scalable production systems for the emergency manufacturing of vaccines and antiviral drugs. | 2020-05-08 |
| 32371096 | Here we report a case of a patient hospitalised in December 2019 in an intensive care unit in a hospital in the north of Paris for haemoptysis with no aetiological diagnosis. […] RT-PCR was performed retrospectively on the stored respiratory sample and confirmed the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. | 2020-05-11 |
| 32371192 | The differential diagnosis between novel coronavirus pneumonia patients (NCPP) and influenza patients (IP) remains a challenge in clinical practice. […] The diagnostic model based on a combination of 18 routine laboratory indicators showed an area under the curve of 0.796 (95% CI, 0.777-0.814), with a sensitivity of 46.93% and specificity of 90.09% when using a cut-off value of 0.598. […] A diagnostic model based on a combination of routine laboratory results provided an adjunct approach in the differential diagnosis between NCPP and IP. | 2020-05-29 |
| 32371416 | Following treatment with oseltamivir and short-term methylprednisolone combined with symptomatic management, all three patients recovered within 3 weeks, as evidenced by the disappearance of their symptoms, clearance of pulmonary infiltrates and consecutive negative molecular diagnostic test findings. | 2020-05-07 |
| 32371417 | Magnetic resonance imaging showed changes in keeping with inflammation of the brainstem and the upper cervical cord, leading to a diagnosis of rhombencephalitis. | 2020-05-06 |
| 32371823 | Finally, a reverse transcriptase polymerase chain reaction (RT-PCR) of a pharyngeal specimen confirmed the diagnosis of COVID-19. | 2020-05-08 |
| 32373061 | However, for acute stroke patients who have a diagnosis of or are under investigation for COVID-19, the concern for nosocomial transmission moderates operational procedures for acute stroke care. | 2020-05-08 |
| 32373990 | This review of current studies on COVID-19 provides insight into the radiological role in the detection, diagnosis, and monitoring for COVID-19. […] A combination of chest CT and repeat Reverse Transcription-Polymerase Chain Reaction (RT-PCR) testing may be beneficial for the diagnosis of COVID-19 in the setting of strongly clinical suspicion. […] Chest CT may improve the sensitivity for COVID-19 diagnosis, but patients’ exposure to radiation should be kept as low as possible especially for children and pregnant women patients. | 2020-05-08 |
| 32373999 | Here we present an overview of the viral structure, pathogenesis, diagnosis, and clinical features of COVID-19 based on the current state of knowledge, and we compare its clinical characteristics with SARS and Middle East Respiratory Syndrome (MERS). | 2020-05-08 |
| 32374001 | In this review, 73 research articles published before 25 March 2020 were analyzed to better understand the clinical characteristics of patients and to introduce the available serological, hematology and molecular diagnostic methods. […] We highlighted the role of HLA haplotype in virus infection as HLA typing will provide susceptibility information for personalized prevention, diagnosis, and treatment in future studies. | 2020-05-08 |
| 32374007 | Here we summarized relatively mature diagnostic methods like nuclear acid test and computed tomography. […] Especially, we also presented several novel techniques for diagnosing COVID-19 like lung ultrasound. […] Chinese Clinical Guidance for COVID-19 Pneumonia Diagnosis and Treatment (7th edition) by National Health Commission is recommended to follow as it provides detailed diagnostic procedures using currently available tools. | 2020-05-08 |
| 32374208 | What are the best diagnostic tests currently available for companion animals and livestock? | 2020-05-28 |
| 32374537 | A limitation of the propagation, the understanding of the functioning of the virus and its clinical manifestations, the administration of specific treatments, rapid and reliable diagnostic tools are the basis of the fight against this germ, which is still little known today. | 2020-05-08 |
| 32374538 | Diagnosis is based on PCR from a nasopharyngeal swab and emergency treatment rely on oxygen therapy. […] Le diagnostic repose sur la PCR à partir d’un frottis nasopharyngé et le traitement d’urgence sur l’oxygénothérapie. | 2020-05-08 |
| 32374545 | The nasopharyngeal smear with PCR analysis is the first diagnostic test proposed to confirm infection with COVID-19 SARS-CoV-2. […] For this reason, the chest CT-scan has been proposed as a rapid triage tool for diagnosis in these suspect Covid-19 patients. […] However, its specificity is limited, exposing to the risk of over-diagnosis, and further data are needed to confirm its usefulness, and to highlight the possible prognostic value of the CT, in detecting early lesions associated with poor outcome, indicating the need for admission to intensive care. […] Aussi, le CT-scan thoracique a été proposé comme outil de triage rapide pour poser le diagnostic chez ces patients suspects de COVID-19. […] Toutefois, sa spécificité est limitée, exposant au risque de surdiagnostic. | 2020-05-08 |
| 32374647 | In early to mid-March, there were no clear guidelines or recommendations available from neurodiagnostic-related organizations or hospitals on how to adapt procedure workflow to those with COVID-19. | 2020-05-06 |
| 32374815 | Autopsies performed at a single academic medical center, as mandated by the German federal state of Hamburg for patients dying with a polymerase chain reaction-confirmed diagnosis of COVID-19. | 2020-05-23 |
| 32374942 | For suspected referrals with cancer, we adapted the Head and Neck Cancer Risk Calculator (HaNC-RC)-V.2, generated from 10 244 referrals with the following diagnostic efficacy metrics: 85% sensitivity, 98.6% negative predictive value, and area under the curve of 0.89. | 2020-05-11 |
| 32375085 | Diverse clinical manifestations and laboratory abnormalities occur in patients with cardiovascular injury in COVID-19, characterizing the development of this complication, as well as providing clues to diagnosis and treatment. | 2020-05-08 |
| 32375144 | The COVID-19 pandemic has stressed patients and healthcare givers alike and challenged our practice of antenatal care, including fetal diagnosis and therapy. | 2020-05-06 |
| 32375487 | This paper describes, besides general measures in times of a pandemic, also the necessary changes in the invasive diagnosis and treatment of patients presenting with different entities of acute coronary syndromes including structural adaptations (networks, spokes and hub centres) and therapeutic adjustments. | 2020-05-29 |
| 32375787 | The government has also made efforts to divulge high-quality information concerning the COVID-19 and to provide laboratories and hospitals with diagnostic kits and adequate resources to treat patients. | 2020-05-11 |
| 32376004 | Psychiatrists need to know: (i) how to identify, the risks associated with the prescription of psychotropic drugs and which can prove to be counterproductive in their association with COVID-19 (coronavirus disease 2019), (ii) how to assess in terms of benefit/risk ratio, the implication of any hasty and brutal modification on psychotropic drugs that can induce confusion for a differential diagnosis with the evolution of COVID-19. | 2020-05-09 |
| 32376306 | We conducted diagnosis of the residuals and also its goodness of fit with testing data from Mar. 13 to Apr. | 2020-05-09 |
| 32376309 | The median number of days to first negative RT-PCR in the asymptomatic carriers was 4.5 (range 2.5-9), and all asymptomatic carriers reached a first RT-PCR Ct>35 within 14 days after diagnosis. […] Patients who have COVID-19 may already be infectious before there are symptoms, and 14 days of isolation after diagnosis may be sufficient in entirely asymptomatic cases. | 2020-05-29 |
| 32376317 | Perinatal exposure, including mode of delivery and time interval from delivery to the diagnosis of neonatal infection are crucial in differentiating congenital from perinatal infection. | 2020-05-10 |
| 32376532 | To standardize the management and facilitate the diagnosis and treatment, we formulated the guidelines for the procedures and strategies for the diagnosis and treatment of AMI, which highlight 5 Key Principles, namely Nearby treatment, Safety protection, Priority of thrombolysis, Transport to designated hospitals, and Remote consultation. | 2020-05-08 |
| 32376543 | To explore the value of the “dandelion clock-like” sign on chest CT for diagnosis of SARS-CoV-2-associated pneumonia. | 2020-05-08 |
| 32376546 | The selection of appropriate detection techniques and methods for accurate and rapid identification of pathogens therefore plays a key role in improving the diagnosis and treatment of the patients and containing the outbreak. […] These techniques are expected to provide valuable assistance in controlling the epidemic and new ideas for future researches. | 2020-05-08 |
| 32376571 | This retrospective study was conducted in 11 patients with established diagnosis of COVID-19 and 10 patients with diseases other than COVID- 19 in our hospital. | 2020-05-11 |
| 32376573 | According to the Fifth Edition of the Diagnosis and Treatment Guidelines by the National Health Commission, the patients were divided into common type, severe type and critical type. […] MSCT volume scanning not only allows early diagnosis of COVID-19 but also provides evidence for evaluating the severity of COVID-19 to assist in the clinical treatment of the patients. | 2020-05-11 |
| 32376581 | Multivariate logistic regression analysis showed that NLR was an independent risk factor for severe COVID-19 (OR=1.264, 95% CI: 1.046-1.526, P=0.015) with an AUC of 0.831 (95% CI: 0.730-0.932), an optimal diagnostic threshold of 4.795, a sensitivity of 0.839, and a specificity of 0.750. | 2020-05-11 |
| 32376583 | We review the experience with the diagnosis and treatment of secondary cerebral infarction in an elderly patient with coronavirus disease 2019 (COVID-19). | 2020-05-11 |
| 32376700 | Assessment of the diagnostic performance of the PHEV S1 ELISA using serum samples (n = 924) collected from 7-week-old pigs (n = 84; 12 pigs per group) inoculated with PHEV, porcine epidemic diarrhea virus, transmissible gastroenteritis virus, porcine respiratory coronavirus, or porcine deltacoronavirus showed that a sample-to-positive cutoff value of ≥0.6 was both sensitive and specific, i.e., all PHEV-inoculated pigs were seropositive from days postinoculation 10 to 42, and no cross-reactivity was observed in samples from other groups. | 2020-05-20 |
| 32376714 | The fundamental role of the spike protein in infectivity suggests that it is an important target for vaccine development, blocking therapy with antibodies and diagnostic antigen-based tests. | 2020-05-07 |
| 32377468 | These findings serve as a practical reference for the clinical diagnosis and medical treatment of children with COVID-19. | 2020-05-09 |
| 32377469 | It also serves as an example of how healthcare providers may need to increase their suspicion for COVID-19 to ensure self-protection and prompt diagnosis in the era of an ongoing pandemic. | 2020-05-09 |
| 32377507 | There remains diagnostic uncertainty regarding the sensitivity of reverse transcription polymerase chain reaction in detection of SARS-CoV-2 from nasopharyngeal specimens. | 2020-05-09 |
| 32377597 | As this pandemic continues, patients with symptoms of RP require diagnostic attention. | 2020-05-10 |
| 32377677 | Viral-PCR and serology are the mainstays of testing but a positive diagnosis may be increasingly supported by radiological findings. | 2020-05-29 |
| 32378459 | This article aims to provide an overview of recent studies on the effectiveness of nanoparticles as diagnostic or antiviral tools against coronaviruses. | 2020-05-07 |
| 32378729 | Last but not least, currently available and possible future therapeutic and diagnostic options are briefly commented on. | 2020-05-29 |
| 32378854 | Together, these findings may inform future research, diagnosis, prevention and treatment of COVID-19. | 2020-05-12 |
| 32379077 | While in some cases a history of fever and/or respiratory distress (e.g. cough or shortness of breath) may suggest the diagnosis, epidemiologic studies indicate that the majority of individuals infected with COVID-19 develop mild to no symptoms. […] A case of sudden unexpected death due to COVID-19 is presented as a means of illustrating common autopsy findings, as well as diagnostic and biosafety considerations. | 2020-05-09 |
| 32379104 | All patients who were ≥65 years of age, presented to the Emergency Department of the participating hospitals during this period with a diagnosis of proximal femoral fracture, and had a minimum follow-up of 10 days were included in the cohort. | 2020-05-07 |
| 32379456 | Although several approaches have been used/developed (or are being developed/suggested) to diagnose COVID-19 infection, no approach is available/proposed for fast diagnosis of COVID-19 infections likely to be fatal. | 2020-05-23 |
| 32379727 | Activities were selected based on existing capacity and determined by the Kenya MoH and included 1) expansion of severe acute respiratory illness (SARI) surveillance sites; 2) piloting of community event-based surveillance; 3) expansion of laboratory diagnostic capacity; 4) training of public health practitioners in detection, investigation, and response to respiratory threats; and 5) improvement of response capacity by the national emergency operations center (EOC). | 2020-05-08 |
| 32379887 | This study evaluated the significance of lymphocyte subsets detection in peripheral blood in the diagnosis and prognosis of coronavirus disease 2019 (COVID-19). […] The counts of CD8+T and CD4+T cells can be used as diagnostic markers of COVID-19 and predictors of disease severity. | 2020-05-29 |
| 32380051 | Given this, based on the Guideline on Diagnosis and Treatment of Coronavirus Disease 2019 in China, the present review summarized the basic information, clinical evidence and published literatures of recommended CPMs against COVID-19. | 2020-05-30 |
| 32380453 | Given that COVID-19 has lately been detected in infected patients’ saliva, the COVID-19 outbreak is an alert that all dental and other health professionals must be vigilant in defending against the infectious disease spread, and it may enable to assess whether non-invasive saliva diagnostic for COVID-19. | 2020-05-20 |
| 32380475 | • Clinical evaluation should guide those needing investigation • Strict adherence to COVID-19 protection measures is necessary • Alternative ways of consultations (telephone, video) should be used • Early discussion with regional/national experts about investigation and management of potential and existing patients is strongly encouraged • Patients with moderate and severe clinical features need urgent investigation and management • Patients with active Cushing’s syndrome, especially when severe, are immunocompromised and social shielding is recommended • In patients with mild features or in whom a diagnosis is less likely, clinical re-evaluation should be repeated at three and six months or deferred until the prevalence of SARS-CoV-2 has significantly decreased • Diagnostic pathways may need to be very different from usual recommendations in order to reduce investigations • When extensive differential diagnostic testing is not feasible, it should be deferred, and medical treatment should be initiated • Transsphenoidal pituitary surgery may be avoided during high SARS-CoV-2 viral prevalence • Medical management rather than surgery will be the used for most patients since the short- to mid-term prognosis depends in most cases on hypercortisolism rather than its cause; it should be initiated promptly to minimize the risk of infection in these immunosuppressed patients. | 2020-05-08 |
| 32380844 | " This article also provides recommended reporting structure for CXR and CT, breaking diagnostic possibilities for both CXR and CT into 3 categories: typical, nonspecific, and negative based on imaging findings with representative images provided. | 2020-05-18 |
| 32380903 | These findings will be of significant use in guiding the development of serologic tests, formulating convalescent plasma therapy strategies, and assessing the longevity of protective immunity for SARS-related coronaviruses in general as well as vaccine efficacy. | 2020-05-11 |
| 32381057 | Hence, it is difficult to make an exclusive diagnosis. […] The clinical data including age, sex, exposure history, laboratory parameters and aetiological diagnosis of all patients were collected. […] With a simple and practical scoring system based on CT imaging features, we can make a hierarchical diagnosis of COVID-19 and non-COVID-19 with different management suggestions. | 2020-05-11 |
| 32381140 | Here, we review the factors underlying this arms race, including fears about personal safety, ongoing uncertainty around how SARS-CoV-2 is transmitted, confusion about what constitutes an aerosol-generating procedure, increasing recognition of the importance of asymptomatic infection, and the limited accuracy of diagnostic tests. | 2020-05-22 |
| 32381426 | The median time from admission to diagnosis of SARS-Cov-2 infection was 34 days (5-61 days). […] In 12 patients (80%), the diagnosis was made after a hospital stay of more than 14 days (15-63 days). | 2020-05-11 |
| 32381430 | Skin lesion development occurred before the onset of respiratory symptoms or COVID-19 diagnosis in 12.5% (9/72) of the patients, and lesions spontaneously healed in all patients within 10 days. […] Infection with COVID-19 may result in dermatological manifestations with various clinical presentations, which may aid in the timely diagnosis of this infection. | 2020-05-11 |
| 32381641 | The rollout of diagnostic testing in the United States was slow, leading to numerous cases that were not tested for SARS-CoV-2 in February and March 2020, necessitating the use of serological testing to determine past infections. | 2020-05-08 |
| 32381642 | The SARS-CoV-2 pandemic has brought a new wave of challenges to health care, particularly in the area of rapid diagnostic test development and implementation. […] Acute diagnosis of COVID-19 infection is critically dependent on detection of SARS-CoV-2 RNA from clinical specimens (e.g. nasopharyngeal swabs). […] While laboratory-developed testing for SARS-CoV-2 is an essential component of diagnostic testing for this virus, the majority of clinical microbiology laboratories are dependent on commercially available SARS-CoV-2 molecular assays. […] In contrast to assays approved or cleared by the Food and Drug Administration for in vitro diagnostic use, assays for the detection of SARS-CoV-2 nucleic acids have Emergency Use Authorization (EUA) from the FDA. | 2020-05-08 |
| 32381643 | We analyzed the diagnostic performance of two high-throughput systems: cobas 6800 and Panther Fusion, and their associated RT-PCR assays with a collection of 389 nasopharyngeal specimens. | 2020-05-08 |
| 32382449 | The SEIR+Q dynamics model was fitted using the daily reported number of confirmed infections and unconfirmed cases by clinical diagnostic criteria up to February 14, 2020 in Wuhan. […] Effective reproductive number R(t) analysis using observed frequencies showed a remarkable decline after the implementation of clinical diagnostic criteria and universal symptom surveys, which was significantly below the R(t) curve estimated by the model assuming that the pre-February 14 trend was carried forward. […] The implementation of clinical diagnostic criteria and universal symptom surveys contributed to a contraction in both the magnitude and the duration of the epidemic in Wuhan. | 2020-05-11 |
| 32382463 | Prompt diagnosis of the case is required to improve patients’ prognosis and control of the outbreak. […] However, patients may present with atypical symptoms that pose a diagnostic challenge. | 2020-05-11 |
| 32382737 | Therefore, combining our immunoassay with real-time RT-PCR might enhance the diagnostic accuracy of COVID-19. | 2020-05-29 |
| 32382746 | It would be difficult to triage patients with COVID-19 based on the typical symptoms of fever and/or cough, although PCR and CT are definitive in diagnosis. | 2020-05-29 |
| 32383182 | To face the new Covid-19 pandemic, the need for early and accurate diagnosis of the disease among suspected cases quickly became obvious for effective management, and for better control of the spread of the disease in the population. […] Since the beginning of this disease epidemic caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), reverse transcriptase polymerase chain reaction (RT-PCR) has routinely been used to confirm diagnosis. | 2020-05-08 |
| 32383254 | Since the SARS-CoV-2 outbreak at the end of December 2019 in China, it has become extremely important to have well-established and validated diagnostic and serological assays for this new emerging virus. | 2020-05-18 |
| 32383370 | To determine the prevalence of these symptoms and to evaluate their diagnostic significance, we (approximately 150 physicians of the Daegu Medical Association) prospectively collected data of cases of anosmia and ageusia from March 8, 2020, via telephone interview among 3,191 patients in Daegu, Korea. […] Anosmia and ageusia seem to be part of important symptoms and clues for the diagnosis of COVID-19, particularly in the early stage of the disease. | 2020-05-13 |
| 32383638 | The prolonged persistence of virus RNA in various body fluids may guide the clinical diagnosis and prevention of onward virus transmission. | 2020-05-08 |
| 32383778 | The patient’s positive test led to a diagnosis of COVID-19. […] The recognition of atypical presentations of COVID-19 infection, such as delirium, is critical to the timely diagnosis, provision of appropriate care, and avoidance of outbreaks within healthcare facilities during this pandemic. | 2020-05-16 |
| 32383963 | To contain the infection risk, a revision of all the protocols that until now have been applied to the examination of bodies that require autopsy services is required. Data source: Currently, the diagnosis and postmortem analysis of positive or suspected COVID-19 cases plays a crucial role in scientific research. […] Scientific papers currently available via the PubMed NCBI search engine on COVID-19 postmortem diagnosis were also examined. Discussion: Throughout the history of medicine, the role of autopsy has been fundamental to the understanding of multiple pathogenic processes that are investigated postmortem through autopsy. | 2020-05-08 |
| 32384019 | Diagnostic performance was performed by receiver operating characteristic curve analysis. | 2020-05-08 |
| 32384153 | The developed RT-RPA assay produced 100% diagnostic sensitivity and specificity when compared to RT-qPCR (n=20). | 2020-05-29 |
| 32385458 | From a dental industry perspective, equipment and product manufacturers and suppliers are building upon, and further developing, the industry’s extremely close relationship and partnership with the dental profession, in order to develop and implement new ways of thinking and new approaches, products and techniques to protect patients and clinicians, focusing on a return to the more widespread provision of dentistry. | 2020-05-13 |
| 32385648 | We reviewed clinical histories of 276 patients with confirmed COVID-19 pneumonia and extracted data on patients who met the diagnostic criteria for COVID-19 severe/fatal pneumonia and had an acute exacerbation starting with mild or common pneumonia. | 2020-05-14 |
| 32385976 | The laboratory diagnosis of SARS-CoV-2 infection is currently based on real-time reverse transcriptase-polymerase chain reaction (RT-PCR) testing, and imaging cannot replace genetic testing in patients suspected of COVID-19. […] The role of chest CT as a diagnostic tool may be increased when the laboratory testing capacities using RT-PCR prove inaccurate or insufficient during a major outbreak of the disease. […] In these settings, a rapid presumptive diagnosis of COVID-19 potentially offered by CT might be an advantage, in addition to obvious benefits of delineating the nature and extent of pulmonary changes. […] In the present paper, we reviewed the diagnostic role of chest CT in COVID-19 patients. | 2020-05-09 |
| 32385985 | In order to reduce the mortality of severe and critical COVID-19, experts from the first-line in related fields in China were organized to analyze, discuss and summarize the diagnosis and treatment of severe and critical COVID-19 patients in Wuhan and other severe epidemic areas, and formulate the expert consensus. | 2020-05-12 |
| 32385990 | In the subject words breakthrough analysis, there were time-related breakthrough points in 1991, 1996 and 2002, and the “diagnosis” and “sequence” were continuous hot spots. | 2020-05-12 |
| 32386011 | Chest imaging examination is an important auxiliary examination method in diagnosis of COVID-19. […] To further standardize the imaging examination and diagnosis of COVID-19, Hunan Society of Radiology together with Imaging Technology Professional Committee of Hunan Medical Association reach an expert consensus document on imaging examination, diagnosis, and control and prevention of nosocomial infection for COVID-19. | 2020-05-13 |
| 32386012 | To design a standardized imaging diagnostic reporting mode for screening coronavirus disease 2019 (COVID-19), and to prospectively verify its effectiveness in clinical practice. […] A new classification and standardized imaging diagnosis report mode of viral pneumonia was established by studying and summarizing the imaging findings of various kinds of viral pneumonia, combining with lesion density, interstitial changes, pleural effusion, lymph nodes, and some special signs. […] The confirmed cases were verified, and the diagnostic efficacy of the standardized imaging reporting system in screening COVID-19 was tested. […] In combination with the above signs, the diagnostic efficacy of COVID-19 was 0.942. […] The standardized imaging diagnosis report mode based on COVID-19 chest image features is effective and practical, which should be popularized. 目的: 设计筛查2019冠状病毒病(coronavirus disease 2019，COVID-19)的规范化影像学诊断报告模式，并在临床实践中前瞻性验证其有效性。 | 2020-05-13 |
| 32386014 | These characteristics are of great value in assisting clinical diagnosis and dynamically observing changes undersuch condition. 目的: 分析2019冠状病毒病不同时期的影像学表现特点，并总结其演变特征。 | 2020-05-13 |
| 32386015 | To determine imaging features of coronavirus disease 2019 (COVID-19) in different stages, and to provide foundations for early diagnosis and treatment. […] Repeat CT examination plays an important role in the early clinical diagnosis and the evaluation for the therapeutic effect on COVID-19 patient. 目的: 通过多阶段观察2019冠状病毒病(coronavirus disease 2019，COVID-19)患者的CT影像学表现，研究COVID-19各期CT影像学特征，为临床早期诊断和治疗提供依据。 | 2020-05-13 |
| 32386016 | To investigate the role of chest CT for the diagnostic work-up for patients with suspected infection of coronavirus disease 2019 (COVID-19). […] Compared with the first nucleic acid-positive patients, the onset time of the first nucleic acid-negative patients was shorter [(3.58±2.94) d], but the diagnosis was longer [(3.92±3.66) d]. […] Chest CT examination is important to avoid COVID-19 missed diagnosis due to false negative nucleic acid. 目的: 探讨肺部CT在2019冠状病毒病(coronavirus disease 2019，COVID-19)临床筛查及早期诊断过程中的作用。 | 2020-05-13 |
| 32386017 | To investigate imaging features of the coronavirus disease 2019 (COVID-19), and to provide concrete evidences for diagnosis of COVID-19. […] The combination of the first chest CT imaging features and SARS-CoV-2 nucleic acid test results as well as reexamination if necessary can help to make the diagnosis of SARS-CoV-2 infection accurately. 目的: 分析2019冠状病毒病(coronavirus disease 2019，COVID-19)患者的首次胸部CT影像学表现，为COVID-19的及时诊断提供可靠依据。 | 2020-05-13 |
| 32386018 | Early screening, early diagnosis, early isolation, and early treatment remain the most effective prevention and control measures. […] Computed tomography (CT) plays a vital role in the screening, diagnosis, treatment, and follow-up of COVID-19, especially in the early screening, with a higher sensitivity than that of real-time fluorescence RT-PCR. […] The combination of CT and artificial intelligence has the potential to help clinicians in improving the diagnostic accuracy and working efficiency. | 2020-05-13 |
| 32386019 | We reported a group of family cluster outbreak cases confirmed in Xiangya Hospital, Central South University, China, and their clinical and image characteristics have been analyzed in order to provide reference for the prevention and early diagnosis of this disease. | 2020-05-13 |
| 32386027 | Significant improvement regarding the pathogenesis, epidemiology, and diagnosis and therapy for the COVID-19 has been achieved to stop the spread of the epidemics. | 2020-05-13 |
| 32386147 | Due to the large number of infected patients and heavy labor for doctors, computer-aided diagnosis with machine learning algorithm is urgently needed, and could largely reduce the efforts of clinicians and accelerate the diagnosis process. […] Chest computed tomography (CT) has been recognized as an informative tool for diagnosis of the disease. […] In this study, we propose to conduct the diagnosis of COVID-19 with a series of features extracted from CT images. | 2020-05-14 |
| 32386435 | 2)(1)(3)(4) This atypical symptom might lead to misdiagnosis, delayed diagnosis, and virus transmission, especially in countries where cutaneous manifestation of COVID-19 has not been reported widely such as in Indonesia. | 2020-05-09 |
| 32386514 | We will include randomized clinical trials comparing any intervention for the treatment of COVID-19 (e.g., pharmacological interventions, fluid therapy, invasive or noninvasive ventilation, or similar interventions) with any comparator (e.g., an “active” comparator, standard care, placebo, no intervention, or “active placebo”) for participants in all age groups with a diagnosis of COVID-19. | 2020-05-13 |
| 32387057 | An abdominal CT scan ruled out a diagnosis of appendicitis and a chest CT scan yielded a diagnosis of SARS-CoV-2 infection. | 2020-05-14 |
| 32387246 | COVID-19 myocarditis diagnosis should be guided by insights from previous coronavirus and other myocarditis experience. […] Where the diagnosis remains uncertain, an endomyocardial biopsy may help identify active cardiac infection through viral genome amplification and possibly refine the treatment risks of systemic immunosuppression. | 2020-05-14 |
| 32387332 | In this review, we describe some currently applied diagnostic approaches, as well as therapeutics and vaccines, to prevent, treat and control further outbreaks of SARS-CoV-2 infection. | 2020-05-16 |
| 32387389 | It is anticipated that this will assist researchers and clinicians in developing better techniques for timely and effective detection of coronavirus infection. | 2020-05-31 |
| 32387409 | Prolonged viral carriage was observed in 47 patients (4.4%) and was associated to a higher viral load at diagnosis (p < .001) but viral culture was negative at day 10. | 2020-05-16 |
| 32387456 | The parameters used for each COVID-19 positive patient were gender, hospitalization, admission to intensive care unit (ICU), death, tumor diagnosis, prostate cancer diagnosis, and androgen-deprivation therapy (ADT). | 2020-05-14 |
| 32387786 | Necessary adaptations in patient management, triage, and diagnosis are evolving in light of the ongoing scientific and clinical findings. | 2020-05-31 |
| 32387823 | With the increased availability of electronic health-care data and spatial analysis techniques, there is great potential to develop algorithms to enable more effective disease surveillance. […] However, GIS techniques, resources, and methods can be used in Pakistan for more effective investigation of vulnerable geographical locations. | 2020-05-31 |
| 32387968 | We evaluated the clinical performance of an immunochromatographic (IC) IgM/IgG antibody assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and chest computed tomography (CT) for the diagnosis of Coronavirus disease 2019 (COVID-19). […] The diagnostic sensitivity of CT scan alone and in combination with the IC assay was 57.9 % (22/38) and 68.4 % (26/38) for the asymptomatic patients and 74.3 % (55/74) and 82.4 % (61/74) for the symptomatic patients, respectively. […] The IC assay had low sensitivity during the early phase of infection, and thus IC assay alone is not recommended for initial diagnostic testing for COVID-19. | 2020-05-29 |
| 32388083 | The example of paediatric laryngo-bronchoscopy for diagnostic purposes or retrieval of an inhaled airway foreign body is used to illustrate the steps however the checklist structure is modifiable for other AGP and adaptable for local needs. | 2020-05-19 |
| 32388470 | So far, one of the major drawbacks of the available molecular assays for the diagnosis of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) is the need for viral nucleic acid extraction from clinical specimens. […] The high sensitivity and specificity of this new assay indicate that it is promising for laboratory diagnosis, enabling highspeed detection in just over one hour, which is significantly faster than the up to five hours currently required by traditional extraction followed by amplification technologies, thus allowing prompt decision making regarding isolation of infected patients. | 2020-05-29 |
| 32388471 | The ongoing SARS-CoV-2 pandemic presents a unique challenge for diagnostic laboratories around the world. | 2020-05-29 |
| 32388472 | Reduced whole blood lymph count can be used as an adjuvant diagnosis of early SARS-CoV-2 infection. | 2020-05-29 |
| 32389516 | In that short period, four patients met the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for a brief reactive psychotic disorder. […] This type of psychosis has a high risk of suicidal behavior and, although short-lived, has a high rate of psychotic recurrence and low diagnostic stability over time. | 2020-05-14 |
| 32389518 | It collects epidemiological variables, contagion and diagnosis data, signs and symptoms, treatments and outcomes. | 2020-05-14 |
| 32389615 | Psychosis diagnosis was associated with viral exposure, treatments used to manage the infection, and psychosocial stress. | 2020-05-15 |
| 32389784 | In order to fight the SARS-CoV-2 pandemic infection, there is a growing need and demand for diagnostic tools that are complementary and different from the RT-PCR currently in use. […] Thus, immunochromatographic tests for the detection of anti-SARS-CoV-2 antibodies may have their place for the diagnostic panel of COVID-19. | 2020-05-19 |
| 32390279 | Knowledge of the cutaneous manifestations of COVID-19 may help in early diagnosis, triage of patients, and risk stratification. | 2020-05-30 |
| 32390523 | At the Covid-19 hospital, 12 patients underwent surgery and 51 patients invasive diagnostic procedures between 22 February and 8 March 2020; in the same period, at the Covid-19-free hospital, 21 patients underwent surgery and 56 patients invasive diagnostic procedures. | 2020-05-11 |
| 32390696 | Telemedicine had been an ideal option for such situations allowing all channels of communication that leverage Information Technology platforms, including voice, audio, text and digital data exchange as a help to diagnosis, prescription and follow up evaluation. | 2020-05-15 |
| 32391234 | We describe the clinical presentation of this patient, the diagnostic process, the laboratory and imaging investigations, as well as the course of treatment. | 2020-05-15 |
| 32391242 | Precision medicine (PM) represents a new paradigm in disease diagnosis, prevention, and treatment. […] Better understanding of pathogenic pathways together with an accurate phenotype classification of patients presented with SARS-CoV-2 infection and symptoms might contribute to a more accurate definition of biomarkers and other diagnostic tools, which may lead to more precise mitigation strategies, personalized pharmacologic options, as well as new biological therapy developments. | 2020-05-15 |
| 32391369 | Patients with a validated diagnosis of COVID-19 and using corticosteroids were included, considering all health outcomes. | 2020-05-15 |
| 32391411 | A combination of purposive and snowball techniques helped to select the respondents via Whatsapp and Facebook from 180 cities/towns in the 6 geopolitical zones of Nigeria. | 2020-05-30 |
| 32391518 | Maternal COVID-19 illness was categorized as mild, severe, or critical.4 The time interval from maternal diagnosis of COVID-19 to delivery was calculated in days. | 2020-05-11 |
| 32391657 | The diagnosis of COVID-19 is largely based on the epidemiological evidence and clinical manifestations, and confirmed by positive detection of virus nucleic acid in respiratory samples. […] Early identification, early isolation, early diagnosis and early treatment are important for clinical management. | 2020-05-12 |
| 32391658 | However, since COVID-19 was a newly emerging disease, more work was warranted to improve strategies of prevention, diagnosis and treatment for COVID-19. | 2020-05-12 |
| 32391659 | Based on Diagnosis and treatment of novel coronavirus pneumonia (trial version 6), and Management of COVID-19: the Zhejiang experience, we summarized the experience in the use of antiviral drugs, corticosteroids, vascular active drugs, antibacterial, probiotics, nutrition support schemes in severe and critically ill COVID-19 patients. | 2020-05-12 |
| 32391662 | To compare the diagnostic efficacy among three RT-PCR test kits for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid detection. | 2020-05-12 |
| 32391664 | A total of 67 patients diagnosed as COVID-19 by nucleic acid testing were collected and divided into 4 groups according to the clinical stages based on Diagnosis and treatment of novel coronavirus pneumonia (trial version 6). | 2020-05-12 |
| 32391666 | To analyze the roles of multidisciplinary team (MDT) in the diagnosis and treatment of suspected cases of coronavirus disease 2019 (COVID-19). […] The efficiency of diagnosis and treatment for suspected COVID-19 patients can be improved with MDT, particularly for complicated cases. | 2020-05-12 |
| 32391670 | High-flow nasal cannula (HFNC) has been utilized widely due to its superiority over other non-invasive respiratory support techniques. | 2020-05-12 |
| 32392007 | The current guidelines for diagnosis and treatment of primary respiratory infections are still useful during the COVID-19 epidemic.Telephone triage of patients with respiratory complaints aims to identify patients with complications or an increased risk of complications.There are no indications to test for SARS-CoV-2 virus in general practice.During this COVID-19 epidemic, protective clothing is recommended in all physical contacts with patients with respiratory complaints.There is no reason to be cautious about using NSAIDs in patients suspected of COVID-19. | 2020-05-20 |
| 32392282 | Among 1438 hospitalized patients with a diagnosis of COVID-19 (858 [59.7%] male, median age, 63 years), those receiving hydroxychloroquine, azithromycin, or both were more likely than those not receiving either drug to have diabetes, respiratory rate >22/min, abnormal chest imaging findings, O2 saturation lower than 90%, and aspartate aminotransferase greater than 40 U/L. | 2020-05-20 |
| 32392948 | Objective: To investigate the application of pulmonary ultrasound in the diagnosis of neonatal COVID-19. Methods: In this retrospective study, the clinical data of 5 infants, who were admitted to the Department of Neonatology in Wuhan Children’s Hospital from 31(st) January to 25(th) February 2020, were collected. […] The sensitivity of pulmonary ultrasound is higher than that of chest X-ray and CT in the diagnosis of pulmonary edema, and could be used in monitoring and evaluation of the disease. 目的： 探讨肺部超声在新生儿新型冠状病毒肺炎（COVID-19）诊断中的应用。 | 2020-05-13 |
| 32393111 | Best efforts are being taken up by worldwide nations to implement effective diagnosis, strict vigilance, heightened surveillance, and monitoring, along with adopting appropriate preventive and control strategies. | 2020-05-27 |
| 32393381 | The top three first symptoms displayed before diagnosis were fever (41.8%), lethargy (33.0%) and muscle aches (30.1%). […] After diagnosis, 88.3% staff experienced psychological stress or emotional changes during their isolation period, only 11.7% had almost no emotional changes. | 2020-05-14 |
| 32393438 | The method then involved using high-throughput techniques to take thousands of images of these samples. […] But first more studies are needed to confirm whether this method is a useful tool for drug selection or diagnosis. | 2020-05-14 |
| 32393447 | Temporary closure of outpatient health facilities in some secondary and tertiary care hospitals have deprived millions of NCD patients of their regular medication and diagnostic health needs. | 2020-05-14 |
| 32394687 | Chest computed tomography (CT) plays an essential role in the diagnosis of viral pneumonia, monitoring disease progression, determination of disease severity, and evaluating therapeutic efficacy. […] Prompt diagnosis of COVID-19 is essential to prevent disease transmission and provide close clinical observation of patients with clinically severe disease. | 2020-05-12 |
| 32394993 | The current study developed a self-report instrument whose items address the specific phobia diagnosis criteria of the DSM-V and tested its initial psychometric properties. | 2020-05-15 |
| 32395494 | To evaluate the diagnostic efficacy of Densely Connected Convolutional Networks (DenseNet) for detection of COVID-19 features on high resolution computed tomography (HRCT). […] Deep learning (DL) with DenseNet can accurately classify COVID-19 on HRCT with an AUC of 0.98, which can reduce the miss diagnosis rate (combined with radiologists’ evaluation) and radiologists’ workload. | 2020-05-15 |
| 32395542 | The epidemic stage of COVID-19 has brought great challenges to the diagnosis and management of colorectal cancer (CRC) patients. | 2020-05-15 |
| 32395550 | The nucleic acid gene detection was positive, and thus the diagnosis of 2019-nCoV was confirmed. | 2020-05-15 |
| 32395673 | Recent data support the diagnostic consistency and potential value of computed tomography (CT) scans to aid early diagnosis of COVID-19. | 2020-05-15 |
| 32395793 | SARS-CoV-2 infection has to be confirmed by virological diagnosis. […] Multiple diagnostic tests are available without enough perspective on their reliability. […] Currently, the RT-PCR detection of the viral genome in respiratory samples is the most reliable test to confirm the diagnosis of an acute SARS-CoV-2 infection. […] Detection of virus antigens on respiratory samples is a quick and easy to use technique; however it has not good specificity and sensitivity and cannot be used for diagnosis and patient management. […] Research should be encouraged to overcome the limits of the currently available diagnostic tests. | 2020-05-13 |
| 32395829 | Consensus was reached on 71/100 statements, predominantly standardisation of OR pathways, OR staffing, and pre-operative screening or diagnosis. | 2020-05-12 |
| 32395897 | Here, we review the types, characteristics and shortcomings of various detection methods, as well as perspectives for the SARS-CoV-2 diagnosis. | 2020-05-31 |
| 32395966 | Protocols for diagnosis, and contact isolation measures, should take these atypical presentations into account. | 2020-05-20 |
| 32396075 | Under the global pandemic of COVID-19, the use of artificial intelligence to analyze chest X-ray (CXR) image for COVID-19 diagnosis and patient triage is becoming important. […] To address this problem, here we propose a patch-based convolutional neural network approach with a relatively small number of trainable parameters for COVID-19 diagnosis. […] Experimental results show that our method achieves state-of-the-art performance and provides clinically interpretable saliency maps, which are useful for COVID-19 diagnosis and patient triage. | 2020-05-14 |
| 32396101 | The article will focus specifically on 1) wearable devices suitable for monitoring the populations at risk and those in quarantine, both for evaluating the health status of caregivers and management personnel, and for facilitating triage processes for admission to hospitals; 2) unobtrusive sensing systems for detecting the disease and for monitoring patients with relatively mild symptoms whose clinical situation could suddenly worsen in improvised hospitals; and 3) telehealth technologies for the remote monitoring and diagnosis of COVID-19 and related diseases. | 2020-05-14 |
| 32396455 | The procedure was performed with percutaneous (10 cases) and open (22 cases) surgical techniques. | 2020-05-12 |
| 32396505 | In response, we developed a diagnostic panel consisting of 3 real-time reverse transcription PCR assays targeting the nucleocapsid gene and evaluated use of these assays for detecting SARS-CoV-2 infection. | 2020-05-12 |
| 32396769 | Current approved drugs or molecules under clinical trials can be a good pool for repurposing through in-silico techniques to quickly identify promising drug candidates. | 2020-05-30 |
| 32396903 | In this review, we discuss present knowledge of the topic, the unique challenges of diagnosis and treatment of VTE, as well as some of the potential mechanisms of increased risk for VTE during the illness. […] Understanding the true impact of VTE on patients with COVID-19 will potentially improve our ability to reach a timely diagnosis and initiate proper treatment, mitigating the risk for this susceptible population during a complicated disease. | 2020-05-12 |
| 32396947 | As the clinical management of gestational hypertension and preeclampsia is the same, assessment of urinary protein is unnecessary in the management once a diagnosis of a hypertensive disorder of pregnancy is made. | 2020-05-12 |
| 32397000 | The general response to the pandemic has included increased measures focused on personal hygiene, social distancing, symptom monitoring, early diagnosis, patient isolation, shelter in place, and public health quarantine. | 2020-05-12 |
| 32397262 | In order to integrate the molecular assays in the diagnosis of SARS-CoV-2, a wide range of serology immunoassays (IAs) have also been developed. | 2020-05-18 |
| 32397399 | A retrospective analysis of patients treated with TCZ matched using propensity score to patients treated with Standard Of Care (SOC) was conducted. Setting: The study was conducted at IRCCS Policlinico San Matteo Hospital, Pavia, Italy, from March 14, 2020 to March 27, 2020. Participants: Patients with a confirmed diagnosis of COVID-19 hospitalized in our institution at the time of TCZ availability. Interventions: TCZ was administered to 21 patients. | 2020-05-13 |
| 32397487 | This review focuses on the role of saliva as both a foe (a common mode of viral transmission via salivary droplets and potentially aerosols) and a friend (as a non-invasive diagnostic tool for viral detection and immune status surveillance) in combating COVID-19. | 2020-05-13 |
| 32397844 | Medical images analysis is one of the most promising research areas, it provides facilities for diagnosis and making decisions of a number of diseases such as Coronavirus. | 2020-05-30 |
| 32397847 | Aim: There is a critical need for effective therapies that are immediately available to control the spread of COVID-19 disease. Material & methods: Gamunex®-C and Flebogamma® DIF (Grifols) intravenous immunoglobulin (IVIG) products were tested using ELISA techniques for antibodies against several antigens of human common betacoronaviruses that may crossreact with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. Results: Both IVIGs showed consistent reactivity to components of the tested viruses. | 2020-05-16 |
| 32397951 | Several studies have been performed in order to develop antiviral drugs, from which a few have been prescribed to patients in addition, several diagnostic tests have been designed to accelerate the process of identifying and treating COVID-19. | 2020-05-13 |
| 32398268 | The diagnosis of mild disease was made clinically which was later reaffirmed by LUS after identifying a bilateral small pleural effusion and a thickened pleural line. | 2020-05-13 |
| 32398273 | These 59 ‘SARS-CoV-2-conserved-unstructured’ genomic regions may be most easily targeted in primer-based diagnostic and oligonucleotide-based therapeutic strategies. | 2020-05-24 |
| 32398322 | Screening of children who have a definitive contact history will facilitate early diagnosis and isolation of all infected children. | 2020-05-13 |
| 32398567 | In this article, we will define the physiological, psychological and social aspects, stages, and components of stress reactions in the context of COVID-19, review the relevant literature on stress reactions, and offer some guidance on how to help patients mitigate the physiological and psychological impact of the pandemic through resilience-building techniques. | 2020-05-13 |
| 32398918 | The psychological impact of the lockdown during COVID 19 on orthopaedic surgeons may become a potential concern that will require addressal through open discussion. diagnostic level 4. | 2020-05-16 |
| 32398954 | We summarized epidemiology, virological characteristics, clinical symptoms, diagnostic methods, clinical treatments, and prevention methods for COVID-19 to present a reference for the future wave of probable CoV outbreaks. | 2020-05-15 |
| 32399453 | The patient developed tachycardia and the echocardiogram confirmed the diagnosis of Takotsubo cardiomyopathy. | 2020-05-16 |
| 32399479 | By the 16-February 2020, total existing diagnosis cases of COVID-19, in china now numbered around 57,255, total cumulative diagnosis is about 68,592, total existing suspicion is about 8228, a total severe existing disease 11,272, the total cumulative cure is about 9671 with more than 1666 cumulative deaths have been reported. | 2020-05-16 |
| 32399481 | The preferred imaging modality is chest computed tomography (CT) which plays an important role in early diagnosis, quarantine, and treatment as well as in the evaluation of therapeutic efficacy. […] Our aims are to improve understanding of this disease and to facilitate early diagnosis and evaluation of therapeutic efficacy. […] Throat swabs were positive for the SARS-CoV-2 nucleic acid, which confirmed the diagnosis of COVID-19. […] Chest CT plays a key role in the diagnosis of COVID-19, providing an accurate diagnosis and is a sensitive technique for evaluation of therapeutic efficacy. | 2020-05-13 |
| 32399515 | Here, based on the African situation, we discuss COVID-19 diagnostic challenges and how they may blunt responses. | 2020-05-16 |
| 32399755 | The aim of the present report is to share a procedure applicable to cases of COVID-19-related death, particularly in cases of death without medical intervention and in the absence of an ascertained SARS-CoV-2 infection and/or COVID-19 diagnosis, therefore providing support for diagnostic activity in the present COVID-19 pandemic. | 2020-05-16 |
| 32399942 | The resultant burden of disease and critical illness has outpaced the diagnostic, therapeutic, and health care professional resources of many clinics and hospitals. | 2020-05-16 |
| 32399995 | There were no significant differences in time delays or severity of clinical symptoms for patients treated by IVT or MT, nor in the distribution of final diagnosis among stroke alerts and stroke unit admissions. | 2020-05-13 |
| 32400049 | PCI was performed in all cases expect two that were diagnosed as suspected myocarditis because of the absence of severe coronary disease and three with apical ballooning at ventriculography diagnostic for Tako-Tsubo syndromes. | 2020-05-13 |
| 32400924 | We provide some practical advice for adapting diagnostic and treatment protocols for children with cancer during the pandemic, the measures taken to contain it (e.g., extreme social distancing), and how to prepare for the anticipated recovery period. | 2020-05-29 |
| 32401064 | Accurate and rapid diagnostic tools are essential for early recognition and treatment of infectious diseases, allowing timely implementation of infection control, improved clinical care and other public health measures to stop the spread of the disease. […] In this review, we summarise current advance regarding diverse CRISPR-Cas systems, including CRISPR-Cas9, CRISPR-Cas12 and CRISPR-Cas13, in the development of fast, accurate and portable diagnostic tests and highlight the potential of CRISPR-Cas13 in COVID-19 Pneumonia and other emerging infectious diseases diagnosis. | 2020-05-26 |
| 32401630 | Computed tomography provided an alternate diagnosis in 53% of patients who did not have COVID-19. […] Chest CT provides prompt diagnosis of COVID-19. | 2020-05-13 |
| 32401931 | Currently, there is no effective treatment and fast diagnosis is still a challenge. | 2020-05-19 |
| 32402056 | Heart transplant and a confirmed diagnosis of COVID-19. […] Twenty-eight patients with HT received a confirmed diagnosis of COVID-19. | 2020-05-20 |
| 32402061 | Diagnostic sensitivity, specificity, and concordance were calculated. […] The Abbott SARS-CoV-2 assay had a diagnostic specificity of 99.4% (95% CI; 96.41-99.98%), and sensitivity of 0.0% (95% CI; 0.00-26.47%) at <3 days post symptom onset, 30.0% (95% CI; 11.89-54.28) at 3-7d, 47.8% (95% CI; 26.82-69.41) at 8-13d and 93.8% (95% CI; 82.80-98.69) at ≥14d. […] Diagnostic specificity on the EI assay was 94.8% (95% CI; 89.96-97.72) if borderline results were considered positive and 96.7% (95% CI; 92.54-98.93) if borderline results were considered negative. […] The diagnostic sensitivity was 0.0% (95% CI; 0.00-26.47%) at <3d, 25.0% (95% CI; 8.66-49.10) at 3-7d, 56.5% (95% CI; 34.49-76.81) at 3-7d and 85.4% (95% CI; 72.24-93.93) at ≥14d if borderline results were considered positive. […] However, diagnostic sensitivity was poor in both assays during the first 14 days of symptoms. | 2020-05-29 |
| 32403007 | Self-collection of nasal and throat swabs offers a reliable alternative to health worker collection for the diagnosis of SARS-CoV-2 and other respiratory viruses and provides patients with easier access to testing, reduces exposure of the community and health workers to those being tested and reduces requirement for PPE. | 2020-05-31 |
| 32403008 | To design and evaluate a molecular diagnostic tool for detection and identification of all currently recognized and potentially future emergent CoVs from the Orthocoronavirinae subfamily. | 2020-05-29 |
| 32403153 | Pulmonary auscultation showed basal soft crackling noises of the left lung FINDINGS AND DIAGNOSIS: Laboratory examination showed increased values for LDH, pro-BNP and CRP and normal values for leucocytes and procalcitonin. […] After a third attempt for a PCR-analysis of a deep oral swab-sample was negative, analysis of a sputum was performed which finally confirmed the diagnosis of COVID-19 associated pneumonia. […] Due to clinical recovery antiviral therapy was not performed after confirming the diagnosis. […] Finally, PCR-analysis of sputum confirmed the diagnosis. | 2020-05-13 |
| 32403176 | Therefore, front-line operations, such as emergency departments (ED), were highly stressed by immediate demand for diagnostic swab-testing, and additional personnel were urgently needed within a short time. | 2020-05-22 |
| 32403190 | Non-emergency endoscopic activity in the UK has been postponed, raising concerns of increased delays in the diagnosis of colorectal cancer and a surge in demand once services resume. | 2020-05-13 |
| 32403194 | This commentary addresses the key paired issues of minimizing performance of diagnostic/staging bronchoscopy in patients with suspected/known lung cancer while maximizing the safety of the procedure with respect to HCW transmission of COVID-19. | 2020-05-13 |
| 32404302 | Modified diagnostic and treatment algorithms are proposed to adapt evidence-based protocols for this unprecedented challenge. | 2020-05-14 |
| 32404473 | By mid-January 2020, a scientist from China published the full genome of the virus, which facilitated the development of accurate molecular diagnostic assays. | 2020-05-14 |
| 32404481 | In response to this ongoing shortage, we began production of VTM in-house in support of diagnostic testing in our hospital network. […] As our diagnostic laboratory was not equipped for reagent production, we took advantage of space and personnel that became available due to closure of the research division of our medical center. | 2020-05-20 |
| 32404482 | We sought to evaluate the utilization and diagnostic yield of blood cultures during the COVID-19 pandemic to determine prevalence and common etiologies of bacteremia, and to inform a diagnostic approach to relieve blood culture overutilization. | 2020-05-14 |
| 32404780 | The patient showed a prolonged manifestation of symptoms and a protracted diagnosis period of COVID-19. | 2020-05-14 |
| 32404786 | The diagnosis was confirmed through RNA-PCR testing. […] RNA-PCR test is still the most reliable diagnostic method, especially for asymptomatic patients. | 2020-05-14 |
| 32404797 | We assessed the diagnostic performance of CXR in consecutive patients presenting at the emergency room at the Policlinico San Donato, Milan, Italy from February 24 to April 8, 2020 for suspected SARS-CoV-2 infection. | 2020-05-14 |
| 32404799 | Computed tomography (CT) has been suggested as a highly sensitive modality for the diagnosis of pulmonary involvement in the early stages of COVID-19. […] The diagnosis of COVID-19 on the basis of the imaging features may be more challenging in patients with preexisting cardiothoracic conditions, such as chronic obstructive pulmonary disease, interstitial lung disease, cardiovascular disease, and malignancies with cardiothoracic involvement. […] Thus, understanding the specific CT manifestations in these special subgroups is essential for a prompt diagnosis. | 2020-05-14 |
| 32404896 | To describe the clinical and analytical features of a coronavirus disease 2019 (Covid-19) infected cohort with SCI to enable accurate diagnosis and to outline prevention measures. […] Diagnosis was confirmed with reverse transcriptase polymerase chain reaction (RT-PCR) of nasal exudate or sputum samples. […] The average delay for diagnostic confirmation was 4 days (interquartile range, 1-10). […] All but one patient showed radiological alterations evident in chest X-rays at the time of diagnosis. | 2020-05-19 |
| 32405071 | Eligible patients using renin-angiotensin system blockers (ACEI/ARBs) with a confirmed diagnosis of COVID-19 will be randomized to a strategy of continued ACEI/ARB treatment versus temporary discontinuation for 30 days. | 2020-05-16 |
| 32405079 | Novel coronavirus infectious disease (COVID-19) has been spreading worldwide, and tracking laboratory indexes during the diagnosis and treatment of patients with severe COVID-19 can provide a reference for patients in other countries and regions. […] We closely tracked the epidemiological history, diagnosis and treatment process, as well as dynamic changes in routine blood indicators, of a severe COVID-19 patient who was hospitalized for 26 days. | 2020-05-31 |
| 32405080 | Monitoring T cell changes has important implications for the diagnosis and treatment of severe patients who may become critically ill. | 2020-05-31 |
| 32405081 | The present analytical paper on the role of point-of-care lung ultrasound in this pandemic examines its diagnostic accuracy, clinical utility, and physical practicality in the intensive care unit. | 2020-05-14 |
| 32405101 | In this prospective study consecutive patients hospitalized in non-intensive care units with diagnosis of COVID-19 pneumonia and D-dimer > 1000 ng/ml were screened for asymptomatic DVT with complete compression doppler ultrasound (CCUS). […] Higher cut-off levels for D-dimer might be necessary for the diagnosis of DVT in COVID-19 patients. | 2020-05-29 |
| 32405232 | Prior to the COVID-19 pandemic in our medical center, a mean of 30 patients per week were admitted with a principal diagnosis of HF. | 2020-05-16 |
| 32405236 | This is a discussion and comparison of the virus structures, transmission characteristics, clinical symptoms, diagnosis, pathological changes, treatment and prevention of the two kinds of viruses, CoVs and IAVs. | 2020-05-23 |
| 32405252 | The SARS-CoV-2 pandemic has created an urgent and unprecedented need for rapid large-scale diagnostic testing to inform timely patient management. | 2020-05-19 |
| 32405254 | With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential. | 2020-05-26 |
| 32405259 | However, EEG technologists should not be put in danger if obtaining an EEG does not significantly advance diagnosis or change management in the patient. | 2020-05-14 |
| 32405270 | As the coronavirus disease 2019 (COVID-19) pandemic sweeps across the world, the availability of viral transport medium (VTM) has become severely limited, contributing to delays in diagnosis and rationing of diagnostic testing. […] Use of PBS as a transport medium has the potential to increase testing capacity for SARS-CoV-2, aiding more widespread screening and early diagnosis of COVID-19. | 2020-05-30 |
| 32405452 | Collected data included the current MS DMT and patient-reported disability level, history of recent sick contact, recent fever, respiratory symptoms, diagnosis with COVID-19, and the disposition after the diagnosis. […] We defined a COVID-19-suspect group as patients having fever and cough or fever and shortness of breath, or a presumptive diagnosis based on suggestive chest computed tomography. | 2020-05-27 |
| 32405509 | We discuss the current knowledge gaps driven by questions around the quality and consistency of clinical trial results, patient selection, diagnostic methodologies, use of suppressive antibiotic therapy, and methods for adverse event reporting. | 2020-05-14 |
| 32405603 | We analysed findings from 35 studies, including 6686 patients with COVID-19, that met inclusion criteria. 29 studies (n=6064) reported gastrointestinal symptoms in patients with COVID-19 at diagnosis, and the pooled prevalence of digestive system comorbidities was 4% (95% CI 2-5; range 0-15; I2=74%). […] Patients who presented with gastrointestinal system involvement had delayed diagnosis (standardised mean difference 2·85 [95% CI 0·22-5·48]; p=0·030; I2=73%). | 2020-05-16 |
| 32405641 | Modified diagnostic and treatment algorithms are proposed to adapt evidence-based protocols for this unprecedented challenge. | 2020-05-20 |
| 32405882 | The diagnosis was somehow delayed because relatives were initially cautious in bringing the patient to the hospital and, here, the work-up focus was on coronavirusrelated aspects as the patient was initially reputed to be infected with COVID-19. | 2020-05-16 |
| 32406374 | To date, the literature is widely heterogeneous regarding the loss of smell; therefore, we advise home isolation measures and/or social distancing, and to carry out diagnostic tests for SARS-CoV-2 when possible in those patients with sudden and severe loss of smell who cannot be promptly evaluated. | 2020-05-14 |
| 32406381 | The timely and accurate diagnosis of infection with severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), remains the cornerstone of efforts to provide appropriated treatment for patients, to limit further spread of the virus and ultimately to eliminate the virus from the human society. […] We focus this article on (a) developments for improvement of diagnosis of specific SARS-CoV-2 virus, (b) laboratory changes in the immunologic and coagulation system, (c) therapeutic options for anticoagulant treatment of seriously affected patients and (d) on the perspectives through improvement of diagnostic and therapeutic medical procedures. | 2020-05-14 |
| 32406522 | This can lead to delayed diagnosis and inappropriate management of infected patients. | 2020-05-14 |
| 32406638 | Evaluation of a diagnostic algorithm for estimating the risk of COVID-19 in patients who are referred to an emergency department for being suspected of having the disease. | 2020-05-20 |
| 32406829 | Deep learning (DL) has proved successful in medical imaging and, in the wake of the recent COVID-19 pandemic, some works have started to investigate DLbased solutions for the assisted diagnosis of lung diseases. […] While existing works focus on CT scans, this paper studies the application of DL techniques for the analysis of lung ultrasonography (LUS) images. […] Experiments on the proposed dataset demonstrate satisfactory results on all the considered tasks, paving the way to future research on DL for the assisted diagnosis of COVID-19 from LUS data. | 2020-05-14 |
| 32407306 | The counting of confirmed and probable COVID-19-associated deaths might not include deaths among persons with SARS-CoV-2 infection who did not access diagnostic testing, tested falsely negative, or became infected after testing negative, died outside of a health care setting, or for whom COVID-19 was not suspected by a health care provider as a cause of death. | 2020-05-15 |
| 32407937 | A ROC was calculated to compare the diagnostic performance of candidate indexes, and dynamic levels of hematological indexes were compared between the two groups. 75 patients were enrolled, with a mean age of 46.6 ± 14 years, and 45 patients were male. | 2020-05-29 |
| 32408156 | These results will provide a helpful reference for diagnosis and clinical treatment of COVID-19 patients. | 2020-05-29 |
| 32408222 | Based on deep learning method, the proposed diagnosis model trained on multi-view images of chest CT images showed great potential to improve the efficacy of diagnosis and mitigate the heavy workload of radiologists for the initial screening of COVID-19 pneumonia. | 2020-05-27 |
| 32408547 | Two techniques were used in the Molecular Operating Environment (MOE) for this purpose, i.e., a ligand-based pharmacophore approach and a molecular docking-based screening. | 2020-05-18 |
| 32409114 | Future studies with long-term follow up and more cases are needed to elucidate COVID-19 diagnosis, outcome, and management strategies for these patients. | 2020-05-18 |
| 32409210 | There were four stroke cases with simultaneously diagnosis of Covid-19 till the April 14, 2020 in the city of Sakarya, Turkey. | 2020-05-18 |
| 32409215 | Hence a high index of suspicion is required for timely diagnosis and isolation of cases to prevent the spread in neurology wards. | 2020-05-16 |
| 32409298 | The COVID-19 pandemic has created major insecurities regarding whether we can and should maintain the current standards of diagnosis and treatment and access to care for patients with cancer. | 2020-05-16 |
| 32409313 | Asymptomatic infections within a population will inevitably lead to diagnosis via unrelated medical imaging. | 2020-05-15 |
| 32409431 | Lung ultrasound has the potential to aid the diagnosis and management of patients with COVID-19 infection. | 2020-05-28 |
| 32409438 | A targeted combination of psychopharmacology (targeting acute anxiety and panic symptoms) and psychotherapy (relaxation techniques, breathing exercises, and encouragement) is recommended. | 2020-05-28 |
| 32409442 | Some of these cutaneous manifestations arise before the signs and symptoms more commonly associated with COVID-19, suggesting that they could be presenting signs of COVID-19. utaneous manifestations are well known to occur in the setting of viral illnesses, and occasionally these manifestations have diagnostic or prognostic value. | 2020-05-16 |
| 32410206 | Patients with confirmed COVID-19 diagnosis hospitalized at the study centers from January 17 to February 10, 2020, were included. | 2020-05-25 |
| 32410236 | Rapid diagnosis and isolation are key to containing the quick spread of a pandemic agent like SARS-CoV-2, which has spread globally since its initial outbreak in Wuhan province in China. […] Epidemiological interventions depend on timely availability of accurate diagnostic tests and throughput capacity of such systems during large outbreaks like SARS-CoV-2. | 2020-05-15 |
| 32410816 | Chest radiography (CXR) and computed tomography (CT) play key roles in managment and diagnosis of COVID-19. | 2020-05-15 |
| 32411552 | The current diagnostic options include real-time polymerase chain reaction (RT-PCR) and a few serology tests, including but not limited to the recently approved five minutes serology tests. […] Anecdotal experiences have shown that imaging characteristics are crucial to diagnosis as radiological evidence of disease appears prior to clinical manifestations and tends to evolve over time, which can be useful in predicting the stage of the disease. | 2020-05-18 |
| 32411619 | The availability of pathogen-specific treatment options for respiratory tract infections (RTIs) increased the need for rapid diagnostic tests. […] Although clinical presentation may be similar among different viruses, associated symptoms may range from a mild cold to a severe respiratory illness, and thus require a fast and reliable diagnosis. […] The second key aspect of this work is a description of new and innovative diagnostic techniques, ranging from biosensors to novel portable and current lab-based nucleic acid amplification methods with the potential future use in point-of-care settings. | 2020-05-19 |
| 32412033 | These techniques have been tested previously and have demonstrated efficacy in reducing or inactivating viral and bacterial pathogens, although testing against SARS-CoV-2 specifically has not been done. | 2020-05-15 |
| 32412509 | In 1981, the first cases of AIDS were reported and wide diagnostic testing helped to characterize high-risk groups and the global burden of the epidemic. […] Diagnostic testing of active and past SARS-CoV-2 infections needs to expand rapidly, ideally using rapid tests. | 2020-05-26 |
| 32412551 | X-ray imaging, although limited to specific visualizations, may be helpful for the diagnosis. […] Training the CNNs from scratch outperforms the other transfer learning techniques, both in distinguishing the X-rays between the seven classes and between Covid-19 and non-Covid-19. | 2020-05-18 |
| 32412556 | In this work, we use mathematical models with time-dependent coefficients, techniques of inverse and forward uncertainty quantification, and sensitivity analysis to characterize essential aspects of the COVID-19 in the three countries mentioned above. | 2020-05-18 |
| 32412790 | OBJECTIVE. Multiple studies suggest CT should be a primary diagnostic tool for coronavirus disease (COVID-19) because they reported sensitivities with CT far superior to that of reverse transcriptase polymerase chain reaction (RT-PCR) testing. […] Chest CT should be considered a supplemental diagnostic tool, particularly for patients who show symptoms. | 2020-05-15 |
| 32413502 | The Pandemic has had ramifications for ways of working, surgical techniques, open vs minimally invasive, theatre workflow, patient and staff safety, training and education. | 2020-05-18 |
| 32413984 | Given that diagnostic systems are intended to help us better understand conditions in order to seek improved outcomes, we propose a more constructive approach to descriptions that uses more positive language, and balances descriptions of deficits with research finding of strengths and differences. | 2020-05-19 |
| 32414384 | Plotting mortality and diagnosis rates against medical staff resources in 16 cities in Hubei Province, where the epidemic was initially concerned and the most severe, shows a significant negative correlation, indicating the critical role of medical staff resources in controlling epidemics. | 2020-05-20 |
| 32414594 | To illustrate the clinical course and difficulties in early diagnosis of coronavirus disease 2019 (COVID-19) in patients after thoracic surgery. […] Insidious symptom onset and misinterpreted postoperative changes on chest computed tomography (CT) resulted in delay in diagnosis. | 2020-05-29 |
| 32414626 | Patients with muscle-invasive bladder cancer are at risk of disease progression, with radical cystectomy delays beyond 12 wk from diagnosis or completion of neoadjuvant chemotherapy. | 2020-05-19 |
| 32414838 | Among the many facets of the SARS-CoV-2 pandemic is the unprecedented pressure it has placed on different points of the supply chain for hospital systems worldwide such as collection devices for the diagnosis of COVID-19. | 2020-05-16 |
| 32415585 | The purpose of this article was to perform a systematic review and meta-analysis regarding the diagnostic test accuracy of chest CT for detecting coronavirus disease 2019 (COVID-19). […] We included studies providing information regarding diagnostic test accuracy of chest CT for COVID-19 detection. […] The methodological quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. | 2020-05-19 |
| 32415767 | In this expert opinion, conceived by the task force involving the Working Groups on Valvular Heart Diseases and Cardiac Surgery as well as the Association of Cardiovascular Intervention of the Polish Cardiac Society, modification of diagnostic pathways, principles of healthcare personnel protection, and treatment guidelines regarding triage and prioritization are suggested. […] Diagnostic tests must be simplified or deferred to minimize the number of potentially dangerous aerosol‑generating procedures, such as transesophageal echocardiography or exercise imaging. | 2020-05-29 |
| 32415815 | In this commentary, we discuss some lessons that we learned as healthcare providers working in a large public hospital during the pandemic, with a special focus on the importance of infection containment and early diagnosis, the role of swab, serological tests, home isolation and individual protection devices, and the available therapies and management indications to better face a possible new outbreak in the near future. | 2020-05-16 |
| 32416069 | However, rapid diagnosis and identification of high-risk patients for early intervention are challenging. […] The AI system can assist radiologists and physicians in performing a quick diagnosis especially when the health system is overloaded. | 2020-05-30 |
| 32416259 | A promising target for both diagnosis and therapeutics treatments of the new disease named COVID-19 is the coronavirus (CoV) spike (S) glycoprotein. | 2020-05-31 |
| 32416289 | We included patients hospitalized at the University Hospital of Rome Tor Vergata, medical center dedicated to the treatment of patients with COVID-19 diagnosis, who underwent an anamnestic interview about sNS consisting of 13 items, each related to a specific symptom, requiring a dichotomized answer. | 2020-05-22 |
| 32416318 | Lung ultrasound (LUS) is a point-of-care ultrasound (POCUS) technique used for its portability, widespread availability, and ability to provide real-time diagnostic information procedural guidance. […] In this context, LUS emerges as a particularly useful tool for the diagnosis and management of patients with cardiopulmonary disease. | 2020-05-22 |
| 32416433 | However, many health workers may be a potential source of infection if not tested with swabs but this diagnostic procedure was not suitable universally in Italy. | 2020-05-29 |
| 32416600 | We conclude that all RT-PCR kits assessed in this study may be used for routine diagnostics of COVID-19 in patients by experienced molecular diagnostic laboratories. | 2020-05-29 |
| 32416785 | In this case-population study, we consecutively selected patients aged 18 years or older with a PCR-confirmed diagnosis of COVID-19 requiring admission to hospital from seven hospitals in Madrid, who had been admitted between March 1 and March 24, 2020. | 2020-05-31 |
| 32416961 | Fluorescence polarization assay showed it has non-specific nucleic acid binding capability, which raised a concern in using it as a diagnostic marker. | 2020-05-20 |
| 32417248 | Nasal and pharyngeal swabs and a nasopharyngeal aspirate were used for conventional and molecular diagnostic assays not including SARS-CoV-2 virus. […] Cell culture still remains the only reference diagnostic method also for emerging viruses, allowing to reveal cytopathogenic viruses and demonstrating their infectivity. | 2020-05-20 |
| 32417870 | As a public health strategy every state has the responsibility of protecting the health of the community and such measures includes the preventive measures like social distancing or even lockdown of the state as a whole restricting the movement of the people, diagnostic measures like testing the suspects, contact tracing and isolation of the patients. | 2020-05-21 |
| 32418377 | However, attention should be paid to acute kidney injury of the elderly patients in the diagnosis and treatment of COVID-19. 目的： 分析新型冠状病毒肺炎（COVID-19）与肾损伤的关系。 | 2020-05-17 |
| 32418559 | Surveillance data on COVID-19 diagnoses can be analysed by the method of back-projection using information about the probability distribution of the time between infection and diagnosis, which is primarily determined by the incubation period. […] These associations were not directly discernible from the daily diagnosis counts, which continued to increase after the first stage of control measures. | 2020-05-29 |
| 32418773 | We propose here adaptations of diagnostic procedures, therapies and care strategies for patients treated for digestive cancer during the COVID-19 epidemic. | 2020-05-29 |
| 32418804 | The purpose of testing for any communicable disease is to support clinicians in the diagnosis and management of individual patients and to describe transmission dynamics. | 2020-05-22 |
| 32419639 | The diagnostic potential of these two types of specimens were showed significant difference (positive rate: 78.2% on throat swabs vs. | 2020-05-18 |
| 32419694 | The preadmission diagnosis of COVID-19 in this patient enabled appropriate management and isolation to prevent nosocomial transmission. | 2020-05-18 |
| 32419750 | Varying degrees of olfactory disturbances may pre-empt the diagnosis of COVID-19. | 2020-05-22 |
| 32419766 | The PAF of COVID-19 diagnosis due to lack of health insurance was 3.3% for counties with <13% black residents and 4.2% for counties with >13% black residents. | 2020-05-22 |
| 32419767 | This article describes a proposed strategy for diagnosis and treatment of diabetic foot ulcers, based on experiences with infection and control strategies during the COVID-19 pandemic in China. | 2020-05-18 |
| 32420073 | Outpatient clinics need to strengthen the differential diagnosis of initial symptoms, pulmonary ground-glass opacity (GGO), consolidation, interstitial and/or interlobular septal thickening, and crazy paving appearance. […] In the routine of oncology, the differential diagnosis of adverse events from COVID-19 is also significant, including radiation pneumonitis, checkpoint inhibitor pneumonitis (CIP), neutropenic fever, and so on. | 2020-05-22 |
| 32420523 | Even though the remaining 20 (95.2%) were negative for at least two reverse transcription PCR tests, 11 (52.4%) patients met the diagnostic criteria for clinically confirmed cases. | 2020-05-22 |
| 32420788 | With the spread of the novel coronavirus, the outpatient lines of hospitals have mostly shut down, which means that routine clinical diagnosis and treatment for autoimmune bullous diseases patients have been disturbed. | 2020-05-18 |
| 32420927 | From the preliminary data of this study, it appears that the Bari Polyclinic has adopted the same therapeutic strategies started in China in the previous months, believing early diagnosis and treatment to be a strength in the battle against COVID-19. | 2020-05-26 |
| 32420937 | Laboratory medicine provides an almost irreplaceable contribution to the diagnostic reasoning and managed care of most human pathologies. […] The etiological diagnosis of COVID-19 is, and will remain for the foreseeable future, deeply based on direct identification of viral RNA by means of molecular biology techniques in biological materials, especially upper and lower respiratory tract specimens. | 2020-05-26 |
| 32420939 | This narrative review starts from diagnostic evaluation, continues with adapted pharmacologic treatment and ends with the recovery phase targeting the nutrition and physical exercise. | 2020-05-26 |
| 32421497 | Given this, there may be no more important time to focus on staff-patient communication and expression of compassion.However, many of the techniques usually employed by emergency clinicians to provide comfort to patients and their families are made more challenging or impossible by the current circumstances. […] Placing emphasis on using these techniques to maximize humanism in the care of COVID-19 patients during this crisis has the potential to bring improvements to ED patient care well after this pandemic has passed. | 2020-05-28 |
| 32421539 | Chest CT has a higher sensitivity and can play an essential role in the diagnosis and treatment of the disease. | 2020-05-22 |
| 32421627 | We spot the urgent needs and highlight innovative diagnostic approaches for targeting various COVID-19 related biomarkers. | 2020-05-29 |
| 32421686 | Unsupervised and supervised machine learning techniques and text analysis were used to identify topics and opinions. | 2020-05-18 |
| 32422376 | We describe the diagnosis, clinical course, and management of the case, including the respiratory failure at presentation, the progression to a scenario characterized by profound inflammatory dysregulation similar to that observed during macrophage activation syndrome, and the clinical improvement after treatment with the IL-1 receptor antagonist anakinra. | 2020-05-20 |
| 32422384 | This review focuses on currently available information on the etiology, clinical symptoms, diagnosis, and mechanism of action of COVID-19. […] Furthermore, we present an overview of diagnostic approaches and treatment of this disease according to available findings. | 2020-05-22 |
| 32422408 | We aimed to investigate the potential use of saliva samples as a non-invasive tool for the diagnosis of COVID-19. […] Saliva might be an alternative specimen for the diagnosis of COVID-19. […] This method could facilitate the diagnosis of the disease, given the simplicity of specimen collection and good diagnostic performance. | 2020-05-30 |
| 32422569 | The main implementation barriers for introduction of a SARSCoV-2 molecular assay in European diagnostic laboratories were availability of positive controls and a specificity panel. | 2020-05-29 |
| 32422662 | Possible additional parameters are POCT (point-of-care-testing) values, electrocardiogram, CT pulmonary angiography, SARS-Cov2-PCR as well as detailed diagnostic of laboratory values. | 2020-05-18 |
| 32422983 | The current outbreak of COVID-19 infection, which started in Wuhan, Hubei province, China, in December 2019, is an ongoing challenge and a significant threat to public health requiring surveillance, prompt diagnosis, and research efforts to understand a new, emergent, and unknown pathogen and to develop effective therapies. | 2020-05-19 |
| 32423024 | Moreover, advances in molecular biology techniques and computational analysis have allowed for the better recognition of the virus structure and the quicker screening of chemical libraries to suggest potential therapies. | 2020-05-19 |
| 32423291 | In the pediatric population, new instances of Kawasaki disease have recently been singled out as presenting in conjunction with or soon after diagnosis of COVID-19. | 2020-05-19 |
| 32423298 | Since March 10, the first day of the lockdown in Italy, diagnostic and therapeutic procedures were limited to emergency and oncology cases, while outpatient procedures and clinical examinations were temporarily suspended to limit virus diffusion and to reallocate personnel into wards dedicated to COVID-19. […] In our otolaryngology unit, between March 10 and April 28, 2020, we performed 96 surgical procedures; they mainly consisted in diagnosis and treatment of malignant tumors of the head and neck (77%), management of acute upper airway obstruction in adults and children (14.7%), drainage of abscesses of the head and neck (6.2%), and treatment of nasal bone fractures (2.1%). | 2020-05-19 |
| 32423299 | Diagnostic flexible laryngoscopy (DFL) is a critical tool in the armamentarium of an otolaryngologist. | 2020-05-19 |
| 32423324 | In contrast to her older age, comorbidities, and cancer diagnosis, she was in a good condition, and there was also no pneumonia finding. | 2020-05-19 |
| 32423435 | Accurate diagnosis requires a comprehensive evaluation of epidemiological, clinical, laboratory and CT imaging data. | 2020-05-26 |
| 32423842 | Due to the wide availability, rapid execution, low cost, and possibility of being acquired at the patient’s bed, chest X-Ray is a fundamental tool in the diagnosis, follow-up and evaluation of the treatment effectiveness of patients with pneumonia, also in the context of COVID-19 infection. | 2020-05-22 |
| 32423899 | Since the availability of resources for diagnostic procedures, surgery and postoperative care, systemic therapy and radiotherapy may differ, the authors have separated the prioritisation analyses. […] Therefore, the redefinition of its diagnostic and therapeutic algorithms with a rigorous method is crucial in order to ensure the highest quality of continuum of care in the broader context of the pandemic and the challenged healthcare systems. | 2020-05-21 |
| 32424616 | Early diagnosis and intervention are keys to the recovery of olfactory disorders. | 2020-05-22 |
| 32425000 | Meanwhile, recent research has revealed critical aspects of SARS-CoV-2 biology and disease pathogenesis; other studies have focused on epidemiology, clinical features, diagnosis, management, as well as drug and vaccine development. | 2020-05-20 |
| 32425010 | Endoscopic diagnosis and treatment constitute an irreplaceable part in the handling of severe COVID-19 cases. […] Endoscopes, as reusable precision instruments with complicated structures, require more techniques than other medical devices in cleaning, disinfection, sterilization, and other reprocessing procedures. […] Based on the experience we attained from the 12 severe COVID-19 cases in our hospital who underwent endoscopy 23 times in total, the article provides an improved version of endoscopic reprocessing guidelines for bedside endoscopic diagnosis and treatment on COVID-19 patients for reference. | 2020-05-20 |
| 32425014 | SARS-CoV-2 infection, responsible for COVID-19, can determine cardiac events, which require a quick diagnosis and management, and should not be overlooked due to the presence of COVID-19 infection. […] In patients with COVID-19, the full cardiovascular disease diagnostic algorithm can be hindered by logistic restrain mainly derived from the difficulty of transporting patients in critical conditions to Radiology or Hemodynamics wards. […] The echocardiography in SARS-CoV-2 pandemic can help for differential diagnosis of cardiac events, which can be related or unrelated by the infection and can likely impact on short-term prognosis. | 2020-05-20 |
| 32425183 | Here we discuss the most common diagnostic procedures and therapeutic activities, the type of personal protective equipment according to the different tests, the timetable of the different diagnostic examinations, the tele-health services or alternative strategies, and the structural and management requirements, that should be applied to protect patients and healthcare providers in the post-COVID-19 era. | 2020-05-20 |
| 32425237 | This review provides a brief understanding of pathophysiology, clinical features, diagnosis and management of COVID-19 and highlights the current knowledge as well as best practices for orthopaedic surgeons. | 2020-05-22 |
| 32425251 | By using the real-time RT-PCR (RT-qPCR) Diagnostic Panel validated by US CDC that targets three regions of the virus nucleocapsid (N) gene, we estimated quantification of SARS-CoV-2 RNA titers in untreated wastewater samples of 5.4 ± 0.2 log10 genomic copies/L on average. | 2020-05-26 |
| 32425268 | Wait-time from the diagnosis of invasive cervical cancer via biopsy to definitive surgery was categorized as: short wait-time (<8 weeks; n = 110) versus long wait-time (≥8 weeks; n = 107). | 2020-05-22 |
| 32425279 | This review summarizes the emergence of SeACoV and updates the research progress made from 2017 to early 2020, mainly focusing on the etiology, epidemiology, evolutionary perspective, potential for interspecies transmission, pathogenesis and diagnosis. | 2020-05-23 |
| 32425294 | In this review we compare the clinical features, diagnosis, and pathogenesis of COVID-CSS with other hematological CSS, namely secondary hemophagocytic lymphohistiocytosis (sHLH), idiopathic multicentric Castleman disease (iMCD), and CAR-T cell therapy associated Cytokine Release Syndrome (CRS). […] Established markers of inflammation as well as cytokine levels are compared and contrasted between these four entities in order to establish a foundation for future diagnostic criteria of COVID-CSS. | 2020-05-22 |
| 32425338 | Considering the broad spectrum of clinical manifestations and the increasing worldwide burden of the disease, there is an urgent need to rapidly scale up the diagnostic capacity to detect COVID-19 and its complications. | 2020-05-29 |
| 32425356 | •Drug eruption preceding COVID-19 symptoms may facilitate early diagnosis. | 2020-05-22 |
| 32425470 | To date, most of the medical literature, including Center for Disease Control guidelines, has relied on three necessary symptoms in making the diagnosis of COVID-19: fever, cough and shortness of breath. | 2020-05-22 |
| 32425646 | Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. […] Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded. […] In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). […] The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. | 2020-05-22 |
| 32425648 | In this study, we aimed to evaluate the diagnostic value of serological assay for SARS-CoV-2. […] The combination of serological assay can greatly improve the diagnostic efficacy. […] After the 11th day post-disease onset, the diagnosis for viral infection should be majorly dependent on serological assay. | 2020-05-23 |
| 32425651 | Therefore, in this review, we outline the epidemiology, clinical symptoms, diagnosis, treatment, prevention, possible immune response and role of thymus in children to combat the COVID-19 outbreak. | 2020-05-22 |
| 32425655 | We compared diagnostic and therapeutic elective procedures requested and performed for PC management from our multidisciplinary team (MDT) during 1 month activity in the highest national level of COVID-19 infection (March 2020) and under restrictions for all the population, with the management performed in a no-COVID-19 month (March 2019) 1 year ago. | 2020-05-19 |
| 32425657 | The SARS-CoV-2 pandemic caused a major surge in needed diagnostic capacity. | 2020-05-22 |
| 32425714 | To demonstrate techniques of laparoscopic surgery while all elective procedures are suspended. […] Stepwise demonstration of key skills required when gardening with minimal access techniques. | 2020-05-19 |
| 32426111 | However, the COVID-19 outbreak may also represent a unique time when pulmonary hypertension experts have to weigh the risks and benefits of the diagnostic work-up including potential exposure to COVID-19 versus initiating targeted pulmonary arterial hypertension therapy in a select high-risk, high likelihood World Symposium Pulmonary Hypertension Group 1 pulmonary arterial hypertension patients. | 2020-05-22 |
| 32426285 | The deceased patients were older people (median age 80 years) and often had a cancer diagnosis (about 20%). | 2020-05-22 |
| 32426754 | Critically ill patients with a diagnosis of coronavirus disease 2019. | 2020-05-22 |
| 32426755 | In this commentary, we provide specific recommendations for the rapid implementation of clinical distancing techniques. | 2020-05-22 |
| 32427000 | There were 69.3% interventional studies, 21.7% observational studies, 5.3% diagnostic tests, and 3.7% other studies. | 2020-05-19 |
| 32427166 | Proposed here is a new but simple concept that would capitalize on the opportunity presented by the on-going natural experiment involving the collection of data from epidemiological surveillance screening and diagnostic testing for clinical treatment. | 2020-05-22 |
| 32427216 | All patients undergo a clinical and virologic diagnostic process before admittance and receive psychosomatic psychotherapeutic inpatient care, possibly beginning under quarantine conditions. | 2020-05-22 |
| 32427226 | Radiology doctors use X-ray or CT images for the diagnosis of Covid-19. | 2020-05-23 |
| 32427468 | Anosmia and agueusia are now well documented and included in the criteria list for diagnosis, and specialists have stressed that doctors screen COVID-19 patients for these two signs. | 2020-05-23 |
| 32427517 | Omics-scale studies on this viral infection are emerging rapidly and offer a tremendous potential to unravel the puzzles of the SARS-CoV-2 pathobiology, and ways forward for diagnostic and therapeutic innovation. | 2020-05-19 |
| 32427569 | Of the available molecular diagnostic options, in addition to RT-PCR it would be advisable to introduce the novel rapid antibody tests which can give quick results, reveal the timeline of the infection, are easy to handle, inexpensive and can be used periodically to monitor HCWs’ viral status during the still unkown duration of the SARS-CoV-2 pandemic. | 2020-05-21 |
| 32427924 | For diagnosis of coronavirus disease 2019 (COVID-19), a SARS-CoV-2 virus-specific reverse transcriptase polymerase chain reaction (RT-PCR) test is routinely used. […] However, this test can take up to 2 d to complete, serial testing may be required to rule out the possibility of false negative results and there is currently a shortage of RT-PCR test kits, underscoring the urgent need for alternative methods for rapid and accurate diagnosis of patients with COVID-19. | 2020-05-19 |
| 32428207 | Polymerase chain reaction (PCR) based tests are optimal and recommended for the diagnosis of an acute SARS-CoV-2 infection. | 2020-05-19 |
| 32428243 | The diagnosis and management of acute promyelocytic leukaemia (APML) in the context COVID-19 poses a challenge for clinicians. | 2020-05-19 |
| 32428957 | Further on diagnosis of a SARS-CoV-2-infection of both patients with a severe course of the male. | 2020-05-22 |
| 32429101 | Moreover, a deeper knowledge of potential changes in the saliva proteome in this disease may allow the identification of new diagnostic and prognostic biomarkers, or even help our understanding of the mechanisms associated with the disease. […] With the development of appropriate sample collection and processing methods and the use of adequate assays, saliva can provide useful clinical information about the disease and could be potentially included in guidelines for sample collection for the diagnosis, disease management, and control of Covid-19. | 2020-05-20 |
| 32429249 | This is a subjective analysis of literature concerning specific topics raised in our daily practice (e.g., clinical features of COVID-19 patients; ventilation of the critically ill COVID-19 patient; diagnostic of infection with SARS-CoV-2; stability of the virus; Covid-19 in specific patient populations, e.g., paediatrics, immunosuppressed patients, patients with hypertension, diabetes mellitus, kidney or liver disease; co-medication with non-steroidal anti-inflammatory drugs (NSAIDs); antiviral treatment) and we believe that these answers help colleagues in clinical decision-making. | 2020-05-20 |
| 32430429 | Timely diagnosis of SARS-CoV-2 infection is a prerequisite for treatment and prevention. […] The serology characteristics and complement diagnosis value of the antibody test to RNA test need to be demonstrated. […] Serology testing provides an important complement to RNA testing in the later stages of illness for pathogenic specific diagnosis and helpful information to evaluate the adapted immunity status of patients. | 2020-05-20 |
| 32431287 | We present our initial experience with COVID-19 in Thailand, focusing on several aspects that may have played a crucial role in curtailment of the pandemic, and elements of care for severely ill COVID-19 patients, including stratification, isolation, and affordable diagnostic approaches and supportive care measures. | 2020-05-20 |
| 32432217 | Nationwide shortages of tests that detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and diagnose coronavirus disease 2019 (COVID-19) have led the US Food and Drug Administration (FDA) to significantly relax regulations regarding COVID-19 diagnostic testing. […] To date the FDA has given emergency use authorization (EUA) to 48 COVID-19 in vitro diagnostic tests and 21 high complexity molecular-based laboratory developed tests, as well as implemented policies that give broad authority to clinical laboratories and commercial manufacturers in the development, distribution, and use of COVID-19 diagnostic tests. […] Currently, there are 2 types of diagnostic tests available for the detection of SARS-CoV-2: (1) molecular and (2) serological tests. […] In this article, the SARS-CoV-2 diagnostic tests currently approved by the FDA under EUA are reviewed, and other diagnostic tests that researchers are developing to detect SARS-CoV-2 infection are discussed. | 2020-05-26 |
| 32432804 | Lessons learnt during the epidemic may help preparation for future epidemics and provide a basis for understanding the pathogenesis, laboratory diagnosis and role of coronaviruses in transfusion medicine. | 2020-05-20 |
| 32432996 | We compared the clinical characteristics of stroke patients with a concurrent diagnosis of COVID-19 to stroke patients without COVID-19 (contemporary controls). […] During the study period in 2020, out of 3556 hospitalized patients with diagnosis of COVID-19 infection, 32 patients (0.9%) had imaging proven ischemic stroke. | 2020-05-30 |
| 32433168 | A retrospective review of her clinical and laboratory data was strongly suggestive for diagnosis of COVID-19 infection. | 2020-05-20 |
| 32434058 | The review explicitly covers the aspects like genome and pedigree of SARS-CoV-2; epidemiology, prognosis, pathogenesis, symptoms and diagnosis of COVID-19 in order to catalog the right information on transmission route, and influence of environmental factors on virus transmissions, for the robust understanding of right strategical steps for proper COVID-19 management. | 2020-05-29 |
| 32434310 | We conducted a proportion meta-analysis to integrate the results of previous studies identified in online databases, and subsequently compared the overlapping of 95% confidence intervals (CIs) between locations of diagnosis. […] When comparing the clinical features according to the location of diagnosis, fever and dyspnea were less frequent in patients diagnosed outside of Wuhan (fever: 78.1%; 95% CI, 73.2% to 82.7%; dyspnea: 3.80%; 95% CI, 0.13% to 12.22%) than in patients diagnosed in Wuhan (fever: 91.7%; 95% CI, 88.0% to 94.8%; dyspnea: 21.1%; 95% CI, 13.2% to 30.3%). […] These results may be attributable to the earlier diagnosis of the disease and the younger age of patients outside of Wuhan although further analysis is needed. […] The role of chest CT in COVID-19 diagnosis is inconclusive based on this study. | 2020-05-21 |
| 32434339 | Diagnostic approaches to COVID-19 include clinical history, PCR tests for the presence of SARS-CoV-2 virus and detection of antibodies. | 2020-05-26 |
| 32434633 | Changes in chest CT scan can be used as an aid for early diagnosis of asymptomatic infection in children. | 2020-05-26 |
| 32434634 | Epidemiological history is of particular importance in the diagnosis of COVID-19 in children aged <18 years. | 2020-05-26 |
| 32434635 | This article reports the diagnosis and treatment of two children with coronavirus disease 2019 (COVID-19) and hypertension. | 2020-05-26 |
| 32434706 | The SARS-CoV-2 pandemic has created an urgent and unprecedented need for rapid large-scale diagnostic testing to inform timely patient management. | 2020-05-29 |
| 32434790 | Herein, we consider diagnostic and therapeutic implications of using ICI during this unprecedented period of COVID-19 infections. […] In particular, we consider the impact of ICI on COVID-19 severity, decisions surrounding continuing or interrupting therapy, diagnostic measures in patients with symptoms or manifestations potentially consistent with either COVID-19 or ICI toxicity, and resumption of therapy in infected patients. | 2020-05-29 |
| 32434891 | Guideline: Diagnosis and management of cardiovascular disease during the covid-19 pandemicPublished by the European Society of Cardiology.This summary is based on the version published on 21 April 2020 (https://www.escardio.org/Education/COVID-19-and-Cardiology/ESC-COVID-19-Guidance). | 2020-05-22 |
| 32435925 | • CT plays a crucial role in early diagnosis and assessment of COVID-19 pneumonia progression. | 2020-05-23 |
| 32436355 | The pandemic of new severe acute respiratory syndrome (SARS) due to coronavirus (CoV) 2 (SARS-CoV-2) has stressed the importance of effective diagnostic and prognostic biomarkers of clinical worsening and mortality. | 2020-05-21 |
| 32436441 | Based on observations described in our letter, we can draw the following conclusions: (1) anosmia must imperatively be added to the list of specific symptoms of COVID-19 infection, (2) anosmia can serve as a free and specific diagnostic tool for developing countries currently affected by the pandemic, (3) the mechanisms of COVID-19 anosmia seem not to directly involve nasal obstruction but rather seem to be related to damage the olfactory neuroepithelium. | 2020-05-21 |
| 32436845 | In this study, we reviewed the AI for diagnostic imaging of COVID-19 pneumonia. | 2020-05-21 |
| 32437004 | Liver injury may be a risk factor for progresses and worsens in patients with COVID-19, and it is necessary to pay attention to the occurrence of liver injury in the diagnosis and treatment of COVID-19. | 2020-05-21 |
| 32437124 | The current outbreak of the pandemic coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) demands its rapid, convenient, and large-scale diagnosis to downregulate its spread within as well as across the communities. […] But the reliability, reproducibility, and selectivity of majority of such diagnostic tests fail when they are tested either to a viral load at its early representation or to a viral gene mutated during its current spread. […] In this regard, a selective “naked-eye” detection of SARS-CoV-2 is highly desirable, which can be tested without accessing any advanced instrumental techniques. […] Thus, the current study reports a selective and visual “naked-eye” detection of COVID-19 causative virus, SARS-CoV-2, without the requirement of any sophisticated instrumental techniques. | 2020-05-28 |
| 32437576 | During the following weeks, at 2 Dutch teaching hospitals, 9 health care workers (HCWs) received a diagnosis of COVID-19, 8 of whom had no history of travel to China or northern Italy, raising the question of whether undetected community circulation was occurring. […] Only 3 (3%) of the HCWs identified through the screening had a history of travel to China or northern Italy, and 3 (3%) reported having been exposed to an inpatient with a known diagnosis of COVID-19 before the onset of symptoms. | 2020-05-30 |
| 32437667 | These techniques are not without limitations. | 2020-05-23 |
| 32437768 | At disease diagnosis, 37 of the 94 (39%) patients (group 1) were managed on an outpatient basis, whereas the remaining 57 (61%) (group 2) required hospitalization. […] The risk of ARDS and death is significant for patients requiring hospital admission at disease diagnosis. | 2020-05-30 |
| 32437932 | This case highlights importance of clinical suspicion of SARS-CoV-2 infection in diagnosis and infectivity assessment. […] We suggest collection of BAL fluid when consecutive nasopharyngeal swabs are negative, to confirm or exclude the diagnosis of COVID-19-associated pneumonia. | 2020-05-23 |
| 32437936 | The differential diagnosis of drug-induced skin rash and hand-foot-mouth disease was ruled out based on the patient’s previous history and course of the disease. | 2020-05-31 |
| 32437942 | We applied thematic analysis and narrative synthesis techniques. | 2020-05-23 |
| 32438256 | For the sake of controlling the infectious coronavirus pneumonia, early diagnosis and quarantine play an imperative role. […] Currently, the mainstream diagnostic methods are imaging and laboratory diagnosis, which differ in their efficacy of diagnosis. […] To compare the detection rate, we reviewed numerous literature on pneumonia caused by coronaviruses (SARS, MERS, and SARS-CoV-2) and analyzed two different ways of diagnosis. […] The results showed that the detection rate of computed tomography (CT) diagnosis was significantly higher than that of real-time quantitative polymerase chain reaction (qPCR) (P = 0.00697). | 2020-05-29 |
| 32438340 | The management of patients with a new diagnosis of hyperthyroidism is best undertaken with a block and replace regimen due to limited biochemical testing availability. […] Patients with COVID-19 infection may present with conjunctivitis, which could cause diagnostic difficulties in patients with new or existing Graves’ ophthalmopathy. | 2020-05-21 |
| 32438345 | Most patients with thyroid nodules and thyroid cancer (TC) referred for diagnostic work-up and treatment are not considered at higher risk of infection from SARS-CoV-2 compared to the general population. […] Accordingly, diagnostic work-up of thyroid nodules, thyroid surgery for either benign or malignant thyroid nodules and radioiodine treatment for differentiated thyroid cancers may be safely postponed during SARS-CoV-2 pandemic. […] For these selected cases diagnostic work-up (e.g. ultrasound, scintigraphy, fine-needle aspiration), surgery and radioiodine therapy may proceed despite the threat of SARS-CoV-2 infection and COVID-19, after an individual risk-benefit analysis. | 2020-05-21 |
| 32438579 | Compared to the former two, the starters (cases 19, 24, and 27) of domestic family cluster infections showed longer symptom-onset to diagnosis (p = 0.02); longer symptom-onset to quarantine or isolation (p = 0.01); higher first-generation reproduction number (p = 0.03); and more critical presentation (endotracheal tube insertion and intensive care unit (ICU) care) (p < 0.01). | 2020-05-22 |
| 32438677 | The emergence of Coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 made imperative the need for diagnostic tests that can identify the infection. […] We used the bivariate method for meta-analysis of diagnostic tests pooling sensitivities and specificities. | 2020-05-22 |
| 32438868 | We further explored the feasibility of ddPCR to detect SARS-CoV-2 nucleic acid from 77 clinical throat swabs, and compared with RT-PCR in terms of the diagnostic accuracy based on the results of follow-up survey. […] Overall, ddPCR shows superiority for clinical diagnosis of SARS-CoV-2 to reduce the false negative reports, which could be a powerful complement to the current standard RT-PCR. | 2020-05-22 |
| 32438876 | To summarize chest computed tomography (CT) manifestations of the early stage of COVID-19 infection and provide a piece of reliable imaging evidence for initial screening and diagnosis. | 2020-05-22 |
| 32438898 | Although some low-income countries have currently reported few cases, it is possible that this is due to limited diagnostic and public health capacity, and may not be reflective of disease occurrence. | 2020-05-27 |
| 32438945 | Diagnostic challenges, the effect of phone consultation on the therapeutic alliance, challenges associated with the use of technology and ethical concerns were identified as issues. | 2020-05-22 |
| 32439651 | Diagnostic performance values of chest CT were a sensitivity of 85.7%, specificity of 75.0%, negative predictive value of 93.8%, and positive predictive value of 54.6%. | 2020-05-29 |
| 32440387 | However, the fear of provoking laryngospasm may cause avoidance of deep or sedated extubation techniques which could reduce coughing and infection risk. […] We review the differential diagnosis of acute airway obstruction after extubation, discuss techniques for achieving smooth extubation with avoidance of coughing and expectoration of secretions, and recommend, on the basis of this review, a clinical pathway for optimal management of upper airway obstruction including laryngospasm to avoid adverse outcomes. | 2020-05-25 |
| 32440661 | We should pay special attention to early diagnosis and early treatment in children infected with COVID-19. | 2020-05-25 |
| 32440666 | This was a retrospective study performed on 63 Iranian adult patients with a final diagnosis of COVID-19. | 2020-05-25 |
| 32440883 | Clinicians around the globe are challenged with rapidly identifying reasonable diagnostic, monitoring and anticoagulant strategies to safely and effectively manage these patients. | 2020-05-25 |
| 32441380 | Diagnosis of Severe Acute Respiratory Coranavirus-2 (SARS-CoV-2) infection is currently based on real-time PCR (RT-PCR) performed on either nasopharyngeal (NPS) or oropharyngeal (OPS) swabs; saliva specimen collection can be used, too. […] Diagnostic accuracy of these procedures is suboptimal, and some procedural mistakes may account for it. […] The video shows how to properly collect secretions from the upper airways for nonserologic diagnosis of COVID-19 by nasopharyngeal swab (NPS), oropharyngeal swab (OPS), and deep saliva collection after throat-cleaning maneuver, all performed under videoendoscopic view by a trained ENT examiner. […] These procedural tricks would enhance diagnostic reliability. | 2020-05-22 |
| 32441935 | A specific and rapid diagnostic method is important for early identification. | 2020-05-22 |
| 32442030 | Although recent American College of Radiology recommendations assert that CT should not be used as a screening or diagnostic tool for patients with suspected COVID-19, radiologists should be familiar with the imaging appearance of this disease to identify its presence in patients undergoing CT for other reasons. MATERIALS AND METHODS. We retrospectively reviewed the CT findings and clinical symptoms of 30 pediatric patients with laboratory-confirmed COVID-19 who were seen at six centers in China from January 23, 2020, to February 8, 2020. […] Eleven of 30 patients (37%) underwent follow-up chest CT, with 10 of 11 examinations (91%) showing no change, raising questions about the utility of CT in the diagnosis and management of COVID-19 in children. CONCLUSION. The present study describes the chest CT findings encountered in children with COVID-19 and questions the utility of CT in the diagnosis and management of pediatric patients. | 2020-05-22 |
| 32442035 | To review multiple streams of evidence regarding the benefits and harms of ventilation techniques for coronavirus infections, including that causing COVID-19. | 2020-05-27 |
| 32442265 | Mean time to diagnosis after close contact with a COVID-19 index patient was 16.0 days (range 1 to 29), and 13.4 days and 18.7 days for those with abnormal and normal CT findings, respectively (p < 0.05). | 2020-05-22 |
| 32442581 | To avoid a downstream public health crisis of avoidable cancer deaths, cancer diagnostic and surgical pathways must be maintained at normal throughput, with rapid attention to any backlog already accrued. | 2020-05-25 |
| 32442684 | After this date, 39 patients with a diagnosis of cancer were operated on in our clinic. | 2020-05-31 |
| 32442699 | Participant demographics, and details of HCQ administration and psoriasis diagnosis were extracted from 15 articles representing 18 patients. | 2020-05-24 |
| 32442720 | At present, the efforts of various countries focus on the rapid diagnosis and isolation of patients, as well as to find a treatment that can combat the most serious impact of the disease. | 2020-05-31 |
| 32442842 | In addition, a novel method is proposed to address the abnormal data on 12-13 February as a result of changing diagnostic criteria. | 2020-05-28 |
| 32443202 | Hospitals are important sources of pollutants resulted from diagnostic, laboratory and research activities as well as medicine excretion by patients, which include active component of drugs and metabolite, chemicals, residues of pharmaceuticals, radioactive markers, iodinated contrast media, etc. | 2020-05-26 |
| 32443442 | The evolving dynamics of coronavirus disease 2019 (COVID-19) and the increasing infection numbers require diagnostic tools to identify patients at high risk for a severe disease course. | 2020-05-25 |
| 32443459 | To date, assays based on the reverse-transcription polymerase chain reaction (RT-PCR) in respiratory samples are the gold standard for COVID-19 diagnosis. […] Consequently, alternative diagnostic methods are urgently required, both for alleviating the pressure on laboratories and healthcare facilities and for expanding testing capacity to enable large-scale screening and ensure a timely therapeutic intervention. […] Therefore, the present systematic review and meta-analysis was undertaken to explore the feasibility of rapid diagnostic tests in the management of the COVID-19 outbreak. […] We can conclude that: (1) rapid diagnostic tests for COVID-19 are necessary, but should be adequately sensitive and specific; (2) few studies have been carried out to date; (3) the studies included are characterized by low numbers and low sample power, and (4) in light of these results, the use of available tests is currently questionable for clinical purposes and cannot substitute other more reliable molecular tests, such as assays based on RT-PCR. | 2020-05-25 |
| 32443828 | Telemedicine, smart phones and apps could represent important devices for the community, in order to prevent virus trasmission and to perform quick diagnosis and management at medical offices. | 2020-05-29 |
| 32443834 | We objectively identified some numerical EEG features in severely ill COVID patients that can allow positive diagnosis of this encephalopathy. | 2020-05-25 |
| 32443856 | The demand to explore the use of EHIS for diagnosis and management of communicable and non-communicable diseases has increased dramatically due to the volume of patient data and the need to retain patients in care. […] With guidance from the presented evidence, we proposed EHIS key stakeholders’ roles and responsibilities to ensure efficient utility of EHIS for disease diagnosis and management at POC in LMICs. | 2020-05-25 |
| 32444412 | Fast diagnosis of COVID-19, and finding high-risk patients with worse prognosis for early prevention and medical resources optimisation is important. […] Here, we proposed a fully automatic deep learning system for COVID-19 diagnostic and prognostic analysis by routinely used computed tomography.We retrospectively collected 5372 patients with computed tomography images from 7 cities or provinces. | 2020-05-23 |
| 32444415 | Five rheumatic cases used hydroxychloroquine before the diagnosis of COVID-19 and none progressed to critically ill stage. […] Differential diagnosis between COVID-19 and a flare of rheumatic disease should be considered. | 2020-05-23 |
| 32444460 | The median age of patients admitted to hospital with covid-19, or with a diagnosis of covid-19 made in hospital, was 73 years (interquartile range 58-82, range 0-104). | 2020-05-28 |
| 32444866 | Patient education for personal hygiene and social distancing measures, along with treatment individualization, telemedicine and continuous surveillance for early diagnosis of COVID-19 are essential. | 2020-05-27 |
| 32445083 | Cancer wards have been subjected to several modifications to protect patients and healthcare professionals from COVID-19 infection, while attempting to maintain cancer diagnosis, therapy, and research. | 2020-05-26 |
| 32445165 | Physicians need to correctly approach this new disease, often representing a challenge in terms of differential diagnosis. […] We consider two different clinical settings, where availability of the different diagnostic strategies differs widely: outpatient and inpatient. | 2020-05-27 |
| 32445195 | Traditional evaluations for making an ALS diagnosis, measuring progression, and planning interventions rely on in-person visits that may now be unsafe or impossible. | 2020-05-23 |
| 32445204 | The Child Neurology Society collaborated with the Pediatric Epilepsy Research Consortium to issue an online statement April 6, 2020 of immediate recommendations to streamline diagnosis, treatment, and follow up of infantile spasms. | 2020-05-23 |
| 32445839 | Many nucleic acid tests based on reverse transcriptase-polymerase chain reaction (RT-PCR) were developed, each with different techniques, specifications and turnaround time. […] For surveillance, the need for serologic tests emerged. […] We concentrate on the point-of-care tests and discuss the basis for new serologic tests. […] A unique situation arose of a communicable and highly contagious disease necessitating the rapid diagnosis of patients and the identification of non-symptomatic infected persons. | 2020-05-25 |
| 32446037 | Early diagnosis is crucial for correct treatment in order to possibly reduce the stress in the healthcare system. […] The standard image diagnosis tests for pneumonia are chest X-ray (CXR) and computed tomography (CT) scan. […] We also explored early and late fusion techniques in the schema in order to leverage the strength of multiple texture descriptors and base classifiers at once. | 2020-05-31 |
| 32446305 | Not only can this create diagnostic confusion, but it could worsen the stigmatization of TB patients especially in LMICs, given the fear of COVID-19. | 2020-05-29 |
| 32446538 | The most important priorities are supposed to be i) The development of potential vaccine candidates to provide protection and interrupt the transmission of SARS-CoV-2, ii) To ensure enough supplies for hospitals and their homogeneous distribution among the countries with the worst number of severe cases, iii) There is a need for more studies to identify potential treatments that are effective for the control of this viral infection and iv) It is imperative to provide easy access to diagnostic kits for all countries affected by this pandemic. | 2020-05-26 |
| 32446902 | In line with the One-Health approach, our evidences provide a molecular structural rationale for a potential role of taxonomically related coronaviruses in conferring protection from SARS-CoV-2 infection and identifying potential candidates for the development of diagnostic tools and prophylactic-oriented strategies. | 2020-05-28 |
| 32447292 | The benefits of regional anesthetic and analgesic techniques on patient outcomes and healthcare systems are evident. […] Regional techniques are now additionally promoted as a mechanism to reduce aerosolizing procedures. […] We hope this will stimulate dialogue and research into the optimal techniques to improve patient outcomes and ensure practitioner safety during the pandemic. | 2020-05-24 |
| 32447328 | Objectives Faced with the COVID-19 pandemic and its impact on the availability and quality of both therapeutic and diagnostic methods, the Belgian authorities have decided to launch a procedure for additional evaluation of the performance of serological tests offered for sale on the national territory. […] Comparison between the LIAISON®SARS-CoV-2 and the ELISA method did not reveal any difference between the two techniques in terms of sensitivities and specificities regarding the determination of the IgG. | 2020-05-27 |
| 32447443 | The consequences of a potentially delayed diagnosis remain to be determined. | 2020-05-27 |
| 32447742 | Moreover, the epidemiology, clinical characteristics, diagnostic procedures, treatments and prevention of the gastrointestinal manifestations of COVID-19 remain to be elucidated. | 2020-05-27 |
| 32447746 | Health care providers currently evaluating patients with neurologic symptoms need consider COVID-19 in any differential diagnosis. | 2020-05-28 |
| 32448085 | Herein, molecular modeling techniques were used with the main goal to obtain candidates from a drug database as potential targets to be used against SARS-CoV-2. | 2020-05-25 |
| 32448136 | Previous studies have shown that the chest CT examination plays an important role in the diagnosis and monitoring of COVID-19. […] The image quality was subjectively evaluated by two senior chest group diagnostic physicians using a 5-point double-blind method. […] CareDose 4D low-dose scanning combined with Karl 3D iterative reconstruction technology can not only greatly reduce the radiation dose, but also provide images that meet the diagnostic criteria of COVID-19, which can be used as a routine method for the follow-up of COVID-19 patients. | 2020-05-28 |
| 32448333 | Despite the reduction in number, urgent cases were on average more challenging owing to diagnostic delay. | 2020-05-28 |
| 32448757 | Consequently, diagnostic cardiovascular evaluations such as echocardiography are a crucial part of the disease management. | 2020-05-28 |
| 32449178 | Multiple regression analyses indicated that COVID-19 pregnant women having a previous psychiatric diagnosis or low income would be more prone to elevated distress and psychiatric symptoms. | 2020-05-25 |
| 32449614 | The aim of this narrative review is to underline gender differences in epidemiology, etiopathogenesis, risk factors, clinical presentation, diagnosis, prognosis and mortality of patients infected with SARS-CoV-2. | 2020-05-26 |
| 32449791 | We tested 40 subjects with a diagnosis of MCI (20) or mild AD (20) from the Cognitive Stimulation Program of Cognitive Disorders Unit. | 2020-05-25 |
| 32450107 | Patients who received one of the treatments of interest within 48 h of diagnosis were included in one of four treatment groups (chloroquine alone, chloroquine with a macrolide, hydroxychloroquine alone, or hydroxychloroquine with a macrolide), and patients who received none of these treatments formed the control group. […] Patients for whom one of the treatments of interest was initiated more than 48 h after diagnosis or while they were on mechanical ventilation, as well as patients who received remdesivir, were excluded. | 2020-05-29 |
| 32450630 | With the update of the “Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia” from the National Health Commission of China, the military medical expert group on the front-line has formulated the “Diagnosis and Treatment Protocol for COVID-19 from Military Medical Team Supporting Wuhan(Trial Version 2)” . | 2020-05-26 |
| 32450631 | COVID-19 could not be excluded if two nucleic acid tests were negative and high-resolution CT was helpful for differential diagnosis. […] Early detection, early isolation, early diagnosis and early treatment are important for good prognosis. | 2020-05-26 |
| 32450712 | This study aims to provide both a model by using cumulative cases and cumulative death toll for SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) outbreak in 4 countries, China, Italy, South Korea, and Turkey, starting from the first diagnosis and to compare associated indicators. | 2020-05-29 |
| 32450761 | We performed a prospective analysis of a series of 27 consecutive patients with COVID-19 comparing both tracheostomy techniques, safety, and prognosis clinical markers. […] The results show that the techniques are equally safe, without cases of infection in surgeons. | 2020-05-26 |
| 32451162 | Relevant publications reporting on the epidemiology of the pandemic, the diagnosis of the severe acute respiratory syndrome coronavirus 2 infection, and the clinical management of cancer and surgical patients, as well as studies concerning health care workers’ safety, were included. […] Real-time polymerase chain reaction was considered the gold standard for the diagnosis of COVID-19, and computed tomography scans were considered useful for cases of diagnostic uncertainty. | 2020-05-29 |
| 32451362 | Considering the high prevalence of CVD, a thorough CVD assessment at diagnosis and early intervention are recommended in COVID-19 patients with CVD. | 2020-05-26 |
| 32451366 | The needed mitigation measures would significantly strain health system capacities, particularly for secondary and tertiary services, while many cases may pass undetected in primary care facilities due to weak diagnostic capacity and non-specific symptoms. | 2020-05-27 |
| 32451655 | All the 140 patients presented to the Emergency Department of the hospital during this period with a diagnosis of fracture, or trauma (sprains, dislocations, wounds) were included in the cohort. […] The COVID-19 diagnosis was confirmed for four patients. […] The frequency of patients with confirmed COVID-19 diagnosis among this population treated in emergency was ten fold higher (2.6%; 4 among 152) than in the general population (0.30%) of the country. | 2020-05-29 |
| 32451808 | This study reviewed the state-of-the-art techniques for CoV prediction algorithms based on data mining and ML assessment. […] The growing emphasis on data mining and ML techniques in medical fields can provide the right environment for change and improvement. | 2020-05-29 |
| 32452050 | Hence, paying more attention to the accurate and immediate diagnosis of suspected and infected cases can be a great help in preventing the rapid spread of the virus, improving the disease prognosis, and controlling the pandemic. […] In this review, we provide a comprehensive and up-to-date overview of the different types of Clinical and Para-clinical diagnostic methods and their practical features, which can help understand better the applications and capacities of various diagnostic approaches for COVID-19 infected cases. | 2020-05-26 |
| 32452195 | The diagnosis is based on the exposure history, clinical manifestation, laboratory test results, chest computed tomography (CT) findings and a positive reverse transcription-polymerase chain reaction (RT-PCR) result for coronavirus disease 2019 (COVID-19). | 2020-05-26 |
| 32452539 | Herein, the COVID-19 structure, epidemiology, pathogenesis, etiology, diagnosis, and therapy have been reviewed. | 2020-05-26 |
| 32452700 | Balancing the need to avoid delays in the diagnosis of breast cancer while avoiding infection requires careful attention to personal protective equipment and physical distancing and vigilance to maintain these practices. […] The collateral damage of delaying diagnosis of breast cancer due to COVID-19 should be avoided when possible. | 2020-05-26 |
| 32452739 | Aerosol sampling was additionally performed in simulated clinical and diagnostic settings. | 2020-05-28 |
| 32452804 | We found that reports of symptoms and diagnosis of COVID-19 significantly predicted daily case counts up to 14 days ahead of official statistics, whereas other COVID-19 posts did not have similar predictive power. | 2020-05-29 |
| 32453196 | Episodes of recurrent wheezing were the most common diagnosis, and 112 children (54%) had hypoxia. | 2020-05-26 |
| 32453695 | After immediate isolation, the patient was transferred to the corresponding medical department, where further investigations verified the diagnosis of COVID-19. | 2020-05-28 |
| 32454253 | Prioritization among oncologic cases represents a difficult task: clinicians have to balance a possible delay in cancer diagnosis or treatment against the risk for a potential COVID-19 exposure. | 2020-05-29 |
| 32454398 | With fewer patients presenting to hospitals with the diagnosis of STEMI, healthcare workers are wondering what is causing this decline. | 2020-05-29 |
| 32454807 | One researcher conducted the search and extracted data on demographics, maternal outcomes, diagnostic tests, imaging, and neonatal outcomes. | 2020-05-29 |
| 32454888 | On March 5, 2020, the National Health Commission of the People’s Republic of China issued the Guidelines for the Diagnosis and Treatment of Novel Coronavirus (2019-nCoV) Infection (Trial Version 7), which integrated traditional Chinese medicine (TCM) into the treatment of COVID-19. | 2020-05-29 |
| 32455058 | Results Ten SpineBoxes were created using a single desktop 3D printer, with accurate replication of the cortico-cancellous interface using previously validated techniques. | 2020-05-29 |
| 32455471 | On March 19th the British Association of Urological Surgeons (BAUS) provided pragmatic guidance for prostate cancer diagnostic services (Table 1).( | 2020-05-26 |
| 32455796 | A reliable rapid diagnostic test for COVID-19 is demanded worldwide. | 2020-05-27 |
| 32456944 | CONCLUSIONS: We detected a high prevalence of COVID-19 with a high percentage detected by screening; hence the need for proactive diagnosis to stop the pandemic. | 2020-05-29 |
| 32457036 | Since the availability of resources for diagnostic procedures, surgery and postoperative care, systemic therapy and radiotherapy may differ, authors did separate prioritisation analyses. […] Therefore, the redefinition of its diagnostic and therapeutic algorithms with a rigorous method is crucial in order to ensure the highest quality of continuum of care in the broader context of the pandemic and the challenged healthcare systems. | 2020-05-29 |
| 32457048 | We conducted a comparative cohort study of patients with rheumatic disease and COVID-19 (confirmed by severe acute respiratory syndrome coronavirus 2 PCR), compared in a 1:2 ratio with matched comparators on age, sex and date of COVID-19 diagnosis, between 1 March and 8 April 2020, at Partners HealthCare System in the greater Boston, Massachusetts area. | 2020-05-27 |
| 32458044 | Diagnosis was made at necropsy and lung histology showed diffuse alveolar damage, edema, and interstitial pneumonia with a geographically heterogeneous pattern, mostly affecting the central part of the lungs. | 2020-05-29 |
| 32458125 | To summarize the chest CT imaging and clinical features of the initial COVID-19 patients and provide a clinical diagnostic method that is more effective and can be performed earlier. […] The median time from initial symptoms to diagnosis was 7 days. | 2020-05-29 |
| 32458174 | • Early in the pandemic, numbers of patients undergoing non-COVID-19 emergent CTs dropped sharply but diagnostic yield did not increase, suggesting potentially undiagnosed emergencies in patients not seen in healthcare institutions. | 2020-05-29 |
| 32458197 | Prompt diagnosis and immediate management of the neurological manifestations of the novel coronavirus will not only improve the prognosis of COVID-19 patients but will also prevent the dissemination of the disease due to misdiagnosed cases. | 2020-05-29 |
| 32458356 | Many countries have made changes to routine management of NCD patients, e.g., cancelling non-urgent outpatient visits, which will have important implications for NCD management, diagnosis of new-onset NCDs, medication adherence, and NCD progression. | 2020-05-29 |
| 32458479 | This study was conducted to evaluate the diagnostic performance of an immunochromatography-based assay of human serum for COVID-19. […] In conclusion, the immunochromatography-based COVID-19 IgG/IgM rapid test is a useful and practical diagnostic assay for detection of COVID-19, especially in the presence of IgM or IgG antibodies. | 2020-05-27 |
| 32458502 | Detection of viral genomic materials by RT-PCR is the gold standard for diagnosis. | 2020-05-27 |
| 32458546 | Given the high mortality rate of the infection, timely and accurate identification of relevant cutaneous manifestations may play a key role in the early diagnosis and management. | 2020-05-27 |
| 32458596 | Medical care decision should be balanced between controlling COVID-19 pandemic spread and timely diagnosis and treatment for gynecologic oncology patients. | 2020-05-27 |
| 32458597 | Other minimally invasive techniques, including, vaginal surgery as well as robotic-assisted and isobaric procedures would be preferred over laparoscopy. | 2020-05-27 |
| 32458599 | Then, chloroquine was included in the Guidelines for the Diagnosis and Treatment of COVID-19 in China (version 6) issued by National Health Commission of the People’s Republic of China. | 2020-05-28 |
| 32459046 | The diagnosis of VTE using standardized objective testing is problematic in these patients, given the risk of infecting non-COVID-19 hospitalized patients and hospital personnel, coupled with the usual challenges of performing diagnostic testing in critically-ill patients. | 2020-05-27 |
| 32459192 | The global coronavirus disease 2019 (COVID-19) has presented major challenges for clinical laboratories, from initial diagnosis to patient monitoring and treatment. […] Initial response to this pandemic involved the development, production, and distribution of diagnostic molecular assays at an unprecedented rate, leading to minimal validation requirements and concerns regarding their diagnostic accuracy in clinical settings. […] In addition to molecular testing, serological assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now becoming available from numerous diagnostic manufacturers. […] The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Task Force on COVID-19 has been established to synthesize up-to-date information on the epidemiology, pathogenesis, and laboratory diagnosis and monitoring of COVID-19, as well as to develop practical recommendations on the use of molecular, serological, and biochemical tests in disease diagnosis and management. | 2020-05-27 |
| 32459574 | None of the authors in published literature, as far as we know, used sequential analysis techniques to test potential drugs for COVID-19. | 2020-05-27 |
| 32459647 | Tongue diagnosis is an important component of TCM diagnosis. […] However, the procedure of obtaining tongue images has not been standardized and the reliability of tongue diagnosis by smartphone tongue images has yet to be evaluated. […] The first objective of this study was to develop an operating classification scheme for tongue coating diagnosis. […] The second and main objective of this study was to determine the intra-rater and inter-rater reliability of tongue coating diagnosis using the operating classification scheme. […] First, tongue images (n=2023) were analyzed by 2 groups of assessors to develop the operating classification scheme for tongue coating diagnosis. […] Based on clinicians’ (n=17) own interpretations as well as their use of the operating classification scheme, the results of tongue diagnosis on a representative tongue image set (n=24) were compared. | 2020-05-27 |
| 32459790 | A chest radiograph led to a pneumonia diagnosis. | 2020-05-30 |
| 32459857 | Thromboembolic events are recognised complications of viral infection, but the diagnosis of an acute pulmonary thrombotic complication in the context of coronavirus disease 2019 (COVID-19) can be challenging because of the similarities of presentation, logistical considerations of diagnosis in a patient isolated for infection control reasons and the effects of cognitive errors in diagnostic reasoning. | 2020-05-29 |
| 32460086 | Collected data included the current MS DMT and patient-reported disability level, history of recent sick contact, recent fever, respiratory symptoms, diagnosis with COVID-19, and the disposition after the diagnosis. […] We defined a COVID-19-suspect group as patients having fever and cough or fever and shortness of breath, or a presumptive diagnosis based on suggestive chest computed tomography. | 2020-05-29 |
| 32460173 | In the context of the pandemic, the rapid emergency use authorisation of diagnostic assays for SARS-CoV-2 has meant there are few peer-reviewed published studies of clinical performance of commercial assays. | 2020-05-29 |
| 32460185 | Construct validity was demonstrated with correlations between CAS scores and demographics, coronavirus diagnosis, history of anxiety, coronavirus fear, functional impairment, alcohol/drug coping, religious coping, hopelessness, suicidal ideation, as well as social attitudes (e.g., satisfaction with President Trump). […] The CAS also demonstrated solid discrimination ability for functional impairment (AUC =0.88), while the original cut score of ≥9 (76% sensitivity and 90% specificity) showed the strongest diagnostic effectiveness among scores. | 2020-05-29 |
| 32460364 | To present seven pediatric patients with appendicitis, all with late diagnosis resulting from different aspects of the fear from the current global COVID-19 pandemic. […] Main reasons for the delayed diagnosis during the COVID-19 era were parental concern, telemedicine use and insufficient evaluation. […] The fear from COVID-19 pandemic may result in delayed diagnosis and higher complication rates in common pediatric medical conditions. […] We believe care givers as well as healthcare providers should not withhold necessary medical care since delay in diagnosis and treatment in these routinely seen medical emergencies may become as big of a threat as COVID-19 itself. | 2020-05-27 |
| 32460457 | Of 113 patients, 54 (47.8%) were asymptomatic at diagnosis, and 15 (13.3%) had no symptoms until they were released from isolation. […] The risk of progression was negligible in COVID-19 patients who met the admission criteria for LTC at the time of diagnosis. | 2020-05-28 |
| 32460829 | Common clinical features mostly consisted of fever and/or cough, while ground-glass opacities were the most common radiologic sign at diagnosis. | 2020-05-29 |
| 32461066 | Linear regression techniques were used to determine slopes for log case count data, and meta analyses were conducted to combine data across states. | 2020-05-30 |
| 32461068 | Administrative support with the aim of zero nosocomial transmission by reducing elective clinical services, decanting wards, mobilizing isolation facilities, providing adequate personal protective equipment, coordinating laboratory network for rapid molecular diagnosis under 4-tier active surveillance for hospitalized- and out-patients, and organizing staff forum and training was implemented under the framework of preparedness plan in Hospital Authority. | 2020-05-30 |
| 32461285 | Background: Several point-of-care (POC) molecular tests have received emergency use authorization (EUA) from the Food and Drug Administration (FDA) for diagnosis of SARS-CoV-2. | 2020-05-28 |
| 32461326 | Between Feb. 21 and Apr. 14, 2020, 117 patients were admitted to the ICU with a confirmed diagnosis of COVID-19. | 2020-05-28 |
| 32461502 | The reported number of new cases underestimates the real spread of COVID-19 pandemic because of non-tested asymptomatic people and limited global access to reliable diagnostic tests. […] In this context, COVID-19 mortality with confirmed diagnosis becomes an attractive source of information to be included in the analysis of perspectives and proposals. | 2020-05-28 |
| 32461973 | Several techniques facilitating the combination of the immunoinformatics approach and comparative genomic approach were used in order to determine the potential peptides for designing the T-cell epitope-based peptide vaccine using the envelope protein of 2019-nCoV as a target. | 2020-05-30 |
| 32462267 | As cardiac injury is a common feature of COVID-19 associated ARDS and is linked with poor outcomes, swift diagnostic management and specialist care of cardiovascular patients in the area of COVID-19 is of particular importance and deserves special attention. | 2020-05-30 |
| 32462289 | Patients with diagnosis of cancer and undergoing treatment further represent a population at risk for worsening cardiopulmonary outcomes. | 2020-05-30 |
| 32462316 | Studies in larger cohorts of currently infected subjects are warranted to confirm (or exclude) the presence of risks for male gametes that are destined either for cryopreservation in liquid nitrogen or for assisted reproduction techniques. | 2020-05-30 |
| 32462398 | A questionnaire of thirty questions was prepared for all NM professionals addressing three main issues: (1) new scheduling praxes for NM diagnostic and therapeutic procedures, (2) assistance of patients with diagnosed or suspected COVID-19, and (3) prevention of COVID-19 spreading in the departments. […] In most departments, scheduled diagnostic and therapeutic procedures were allowed but quantitatively reduced (112/220, 51%). […] A significant reduction of diagnostic and therapeutic procedures (more than 20%) affected 198/220 (90%) and 158/220 (72%) departments, respectively. | 2020-05-30 |
| 32462445 | To define the uniqueness of chest CT infiltrative features associated with COVID-19 image characteristics as potential diagnostic biomarkers. […] One of the considered models showed non-trivial, but moderate diagnostic ability overall (AUC of 0.70 with 99% CI 0.56-0.85). | 2020-05-31 |
| 32462501 | The rates of agreement were 92.7% and 100% with the GeneFinder COVID-19 plus (Elitech) and the diagnosis of the infectious disease specialist respectively. | 2020-05-28 |
| 32462666 | The LPR diagnosis was based on RSI>13, which is the threshold used by Belafsky et al. to suspect LPR.2 This article is protected by copyright. | 2020-05-28 |
| 32462675 | The resumption of non-urgent electrodiagnostic (EDX) testing faces unique challenges due to the long duration of the procedure and direct close contact with patients, including studies with risk of exposure to oropharyngeal secretions. | 2020-05-28 |
| 32462724 | This review article synthesizes the reported imaging findings in pediatric COVID-19 across the literature, offers imaging differential diagnostic considerations and useful radiographic features to help differentiate these entities from COVID-19, and provides recommendations for ordering imaging studies to evaluate suspected cases of pediatric COVID-19. | 2020-05-28 |
| 32462744 | Based on these results, a shortlist of 14 peptides from the N, S, and M main structural proteins that could be used for targeted mass-spectrometry method development and diagnostic of the new SARS-CoV-2 is proposed and the best candidates are commented. | 2020-05-28 |
| 32462756 | Cancer patients are advised to stay at home in case of potential infection, which may cause delays of routine diagnosis and necessary treatment. | 2020-05-28 |
| 32462770 | At present, the diagnosis of this infectious form of coronavirus pneumonia is largely dependent upon a combination of laboratory testing and imaging analyses of variable diagnostic efficacy. […] In the present report, we reviewed prior literature pertaining to the diagnosis of different forms of pneumonia caused by coronaviruses (SARS, MERS, and SARS-CoV-2) and assessed two different potential diagnostic approaches. […] We ultimately found that computed tomography (CT) was associated with a higher rate of diagnostic accuracy than was a real-time quantitative polymerase chain reaction (qPCR)-based approach (P = 0.0041), and chest radiography (P = 0.0100). | 2020-05-28 |
| 32463434 | The rapidly developing pandemic has posed great challenges to diagnosis of this novel infection. […] The immune-associated host transcriptional signatures of COVID-19 hold promise as a tool for improving COVID-19 diagnosis and indicating disease severity. | 2020-05-28 |
| 32464579 | Ninety-five patients underwent 2-3 SARS-CoV-2 nucleic acid tests and received a definitive diagnosis of COVID-19. | 2020-05-30 |
| 32464670 | Here, patient safety and employee protection are equally important.In cooperation with the Institute for Medical Microbiology and Hospital Hygiene and the occupational medical service, interventions were defined to develop solutions to minimize the COVID-19 transmission risk for examiners and patients despite limited diagnostic and equipment resources. | 2020-05-28 |
| 32466199 | In this paper, two artificial intelligence techniques, including an artificial neural network (ANN) based on particle swarm optimization (PSO) algorithm and differential evolution (DE) algorithm, were used for prioritizing climate and urban parameters. | 2020-05-29 |
| 32466458 | The past three unprecedented outbreaks of emerging human coronavirus infections at the beginning of the 21st century have highlighted the importance of readily available, accurate, and rapid diagnostic technologies to contain emerging and re-emerging pandemics. […] Even though excellent techniques are available for the diagnosis of symptomatic patients with COVID-19 in well-equipped laboratories; critical gaps still remain in screening asymptomatic people who are in the incubation phase of the virus, as well as in the accurate determination of live viral shedding during convalescence to inform decisions for ending isolation. […] This review article aims to discuss the currently available laboratory methods and surveillance technologies available for the detection of COVID-19, their performance characteristics and highlight the gaps in current diagnostic capacity, and finally, propose potential solutions. […] We also summarize the specifications of the majority of the available commercial kits (PCR, EIA, and POC) for laboratory diagnosis of COVID-19. | 2020-06-02 |
| 32466536 | Liquid biopsy is considered a revolutionary technique that is opening unexpected perspectives in the early diagnosis and, in therapy monitoring, severe diseases, including cancer, metabolic syndrome, autoimmune, and neurodegenerative disorders. […] Although nanotechnology based on graphene has been poorly applied for the rapid diagnosis of viral diseases, the extraordinary properties of graphene (i.e., high electronic conductivity, large specific area, and surface functionalization) can be also exploited for the diagnosis of emerging viral diseases, such as the coronavirus disease 2019 (COVID-19). […] This review aimed to provide a comprehensive and in-depth summarization of the contribution of graphene-based nanomaterials in liquid biopsy, discussing the remaining challenges and the future trend; moreover, the paper gave the first look at the potentiality of graphene in COVID-19 diagnosis. | 2020-05-29 |
| 32466577 | Diagnostic methods might not work if the variations or deletions are in target regions for the detection of the pathogen. | 2020-05-29 |
| 32466623 | The Coronavirus pandemic stresses the importance of eHealth techniques to monitor patients at home. | 2020-05-29 |
| 32466738 | The increasing trend in the prehospital diagnosis of stroke activated by 911 calls stopped abruptly in the region, regressing to 2019 levels. | 2020-05-29 |
| 32466862 | According to the available evidence, it seems reasonable to apply isolation, hygiene and social distancing measures in patients with recent olfactory disorders as the only symptom, although the usefulness of diagnostic tests for this type of patient should be studied. | 2020-05-31 |
| 32467189 | Their initial work-up did not suggest COVID-19 as a diagnosis but showed unsuspected/incidental lung findings, which led to further investigations and a diagnosis of COVID-19. | 2020-05-29 |
| 32468193 | Recommendations regarding the diagnosis and management of postintubation dysphagia in COVID-19 patients are described in this contemporary review. | 2020-05-31 |
| 32468229 | Disease stage represents the most important prognosis factor; therefore, early diagnosis is essential for melanoma patients’ survival rates. […] These measures could cause a delay in melanoma diagnosis and management leading to an increase of morbidity, mortality and healthcare costs. | 2020-05-31 |
| 32468845 | These recommendations aim to assist radiologists involved in emergency diagnostic imaging to help mitigate the spread of COVID-19 and continue to add value to patient care in the emergency setting. | 2020-05-29 |
| 32469164 | Here, we provide some suggestions for early identification of COVID-19 and differential diagnosis in patients with lung cancer who have fever and respiratory symptoms. […] KEY POINTS: Significant findings of the study This article provides suggestions for early identification of COVID-19 and differential diagnosis in patients with lung cancer with fever and respiratory symptoms. | 2020-06-12 |
| 32469614 | We identified all patients with a diagnosis of HIV who tested positive for SARS-CoV-2 at University of Chicago Medicine between March 1, 2020, and April 7, 2020. […] All were taking antiretroviral therapy (ART) with CD4 count >200 cells/mm3 and suppressed HIV viral loads at the time of COVID-19 diagnosis. | 2020-05-29 |
| 32469732 | Chest X-ray, compared to CT, can be considered a reliable diagnostic tool, especially in the Emergency setting. | 2020-05-31 |
| 32469844 | Both international and national data show that telemedicine can play a major role in the triage process, early identification, diagnosis and treatment of infected individuals, and management of patient pathways in a way that ensures the medical team does not come into contact with potentially infected patients. | 2020-06-02 |
| 32470120 | Demographic variables and pre-crisis depression diagnosis had previously been reported. […] Findings held after additionally controlling for pre-crisis reports of depression diagnosis. | 2020-05-29 |
| 32470212 | We appreciate the article’s suggestions on protection in ophthalmic diagnosis and treatment, but believe that the data and conclusions in meta-analysis need further study. | 2020-05-29 |
| 32470577 | In the present high throughput virtual screening study, we used in silico techniques like receptor-ligand docking, Molecular dynamic (MD), and ADME properties to screen natural compounds. | 2020-05-31 |
| 32470885 | The SARS-CoV-2 pandemic caused a major surge in needed diagnostic capacity. | 2020-05-29 |
| 32471001 | At infection diagnosis, mTOR inhibitors or mycophenolate were withdrawn. | 2020-05-29 |
| 32471703 | Laboratory activity becames essential for the timely diagnosis. | 2020-05-30 |
| 32471794 | The laboratory findings revealed normal WBC and CRP despite apparent lung infiltrations, and typical observations on CT imaging were important diagnostic clues. […] In the domestic endemic situation, a comprehensive evaluation of the clinical course, and laboratory and radiological findings was required for diagnosis. | 2020-05-30 |
| 32471894 | The recent emergence of the SARS-CoV-2 pandemic has posed formidable challenges for clinical laboratories seeking reliable laboratory diagnostic confirmation. […] The swift advance of the crisis in the United States has led to Emergency Use Authorization (EUA) facilitating the availability of molecular diagnostic assays without the more rigorous examination to which tests are normally subjected prior to FDA approval. | 2020-05-30 |
| 32471903 | Age, sex, smoking status, rheumatic disease diagnosis, comorbidities and rheumatic disease medications taken immediately prior to infection were analysed. | 2020-05-30 |
| 32471930 | The role of percentage saturation of hemoglobin with oxygen (oxygen saturation), blood pressure and early use of point-of-care ultrasound in differential diagnosis and specific management is detailed. | 2020-05-30 |
| 32472024 | We strongly recommend that decision-makers:ensure early isolation of symptomatic patients and rapid identification of their contacts;maximize testing rapidly, especially among people with multiple daily contacts with infected populations, high exposure to the public in essential services;rapidly increase diagnostic capacity by mobilizing trained personnel capable of performing rRT-PCR on respiratory samples;equip the population with protective masks. | 2020-05-30 |
| 32472403 | The safety of minimally invasive procedures during COVID pandemic remains hotly debated, especially in a country, like Italy, where minimally invasive techniques have progressively and pervasively entered clinical practice, in both the hepatobiliary and pancreatic community. | 2020-05-30 |
| 32472459 | Since the beginning of the COVID-19 outbreak, a growing body of information on diagnostic and therapeutic strategies has emerged, mainly based on preliminary experience on retrospective studies or small case series. | 2020-05-30 |
| 32472990 | Our knowledge regarding diagnostic approaches, therapeutic management and preventive measures is constantly enriched throughout an abundance of ongoing research in the respective fields. | 2020-05-30 |
| 32472991 | We summarize what makes SARS-CoV2 different from previous highly pathogenic coronaviruses and why it is so contagious, with focus on its clinical presentation and diagnosis, which is mandatory to start the appropriate management and reduce the transmission. | 2020-05-30 |
| 32473009 | We used the national surveillance database of COVID-19 in mainland China to compared gender differences in attack rate (AR), proportion of severe and critical cases (PSCC) and case fatality rate (CFR) in relation to age, affected province, and onset-to-diagnosis interval. […] After adjusting for age, affected province and onset-to-diagnosis interval, the female-to-male difference in AR, PSCC and CFR remained significant in multivariate logistic regression analyses. | 2020-05-30 |
| 32473085 | The diagnosis was complicated by two negative tests for SARS-COV-2, and high-clinical suspicion from the patient’s occupational history led to additional testing in order to confirm the diagnosis. | 2020-05-30 |
| 32473124 | Autopsies were performed on ten African American decedents aged 44-78 years with cause of death attributed to COVID-19, reflective of the dominant demographic of deaths following COVID-19 diagnosis in New Orleans. | 2020-05-30 |
| 32473179 | Utilizing techniques to experimentally contaminate FFRs with a range of microorganisms, most decontamination methods appear to reduce the risk of the mask as a source of infection to the wearer and others to negligible levels. | 2020-05-30 |
| 32473390 | In future its required to provide medicinal plant based clinical products (Masks, sanitizers, soap etc.) with better techniques by clinicians to contend the scarcity and expose towards the nature based medicine rather than chemical drugs. | 2020-05-30 |
| 32473657 | Age and CD4 cell counts in 51 patients diagnosed with COVID-19 were similar to those in 1288 HIV-infected individuals without; however, 32 (63%) with COVID-19 had at least one comorbidity (mostly hypertension and diabetes) compared with 495 (38%) without COVID-19 (p=0·00059). 37 (73%) patients had received tenofovir before COVID-19 diagnosis compared with 487 (38%) of those without COVID-19 (p=0·0036); 11 (22%) in the COVID-19 group had previous protease inhibitor use (mostly darunavir) compared with 175 (14%; p=0·578). | 2020-06-03 |
| 32473681 | We collected data on baseline clinical conditions, medications, cancer diagnosis and treatment, and COVID-19 disease course. […] The primary endpoint was all-cause mortality within 30 days of diagnosis of COVID-19. | 2020-06-23 |
| 32473682 | We excluded patients with a radiological or clinical diagnosis of COVID-19, without a positive RT-PCR test. […] From March 18, to April 26, 2020, we analysed 800 patients with a diagnosis of cancer and symptomatic COVID-19. 412 (52%) patients had a mild COVID-19 disease course. 226 (28%) patients died and risk of death was significantly associated with advancing patient age (odds ratio 9·42 [95% CI 6·56-10·02]; p<0·0001), being male (1·67 [1·19-2·34]; p=0·003), and the presence of other comorbidities such as hypertension (1·95 [1·36-2·80]; p<0·001) and cardiovascular disease (2·32 [1·47-3·64]). 281 (35%) patients had received cytotoxic chemotherapy within 4 weeks before testing positive for COVID-19. | 2020-06-23 |
| 32473756 | NMS diagnosis was confirmed, and both, favipiravir and risperidone were discontinued on day 8. | 2020-06-05 |
| 32473875 | Analysis focused on trends in comorbidities, number of cases, number of deaths, and case-fatality rate among patients with and without IDD who had a positive diagnosis for COVID-19 through May 14, 2020. | 2020-06-03 |
| 32473953 | To evaluate the diagnostic performance of seven rapid IgG/IgM tests and the Euroimmun IgA/IgG ELISA for antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in COVID-19 patients. […] Positivity of IgM OR IgG for LFA resulted in a decrease in specificity compared to IgG alone without a gain in diagnostic performance, except for VivaDiag. […] The results for IgM varied significantly, and including IgM antibodies in addition to IgG for the interpretation of LFAs did not improve the diagnostic performance. | 2020-06-13 |
| 32473977 | Therefore, we unfolded SARS-CoV-2 viral genome to shed light on its gene expression regulation that could help to design and evaluate diagnostic tests, to track and trace the ongoing outbreak and to identify potential intervention options. | 2020-06-27 |
| 32474129 | Active tracking, rapid diagnosis, and aggressive source control can mitigate the adverse effects on treatment delays, workforce incapacitation, and ideally outcomes. | 2020-06-26 |
| 32474280 | The mainstay approach for epidemics has long involved the large-scale application of diagnostic testing at the individual case level. […] WBE measures chemical signatures in sewage, such as fragment biomarkers from the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), simply by applying the type of clinical diagnostic testing (designed for individuals) to the collective signature of entire communities. | 2020-06-24 |
| 32474371 | The diagnostic capability was centred on an IVD CE-marked RT-PCR kit and designed to provide surge capacity to the nearby Queen Elizabeth Hospital. | 2020-06-18 |
| 32474389 | COVID-19 can be detected through salivary diagnostic testing which has lots of advantages for medical care professionals and patients. | 2020-06-26 |
| 32474578 | In this report, we present temporal data on influenza-like illness, influenza diagnosis and COVID-19 cases for all four regions of New York State through the first six weeks of the outbreak. | 2020-05-31 |
| 32474632 | This review describes the imaging features for diagnosis, stratification, and follow-up of COVID-19 patients. | 2020-06-03 |
| 32474676 | They are broadly organized by (1) substituting a noninvasive diagnostic test in place of a semi-invasive or invasive diagnostic tests, and (2) consolidating diagnostic imaging. | 2020-06-03 |
| 32475012 | Specifically, we aim to elaborate on the regulatory complexities of diagnostic testing in the U.S. and its implications to the present outbreak, as well as provide a synopsis of laboratory tests that have been developed for COVID-19. […] Subsequently, we will provide an overview of serological tests that can aid not only in diagnosis but additionally help to identify prior infections and potential immunity. | 2020-06-19 |
| 32475088 | Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of patients and health care providers (HCP). | 2020-06-01 |
| 32475230 | Among them, IL-6 and IL-10 can be used as predictors for fast diagnosis of patients with higher risk of disease deterioration. | 2020-06-02 |
| 32475877 | The false-negative nasopharyngeal swabs of SARS-CoV-2 caused the delayed diagnosis of COVID-19 which hindered the prevention and control of the pandemic. […] Serologic detection for anti-SARS-CoV-2 IgG and/or IgM is an important test in the assistant diagnosis of COVID-19. | 2020-06-01 |
| 32476126 | Using PubMed, Embase and Medline, articles published between January and April 2020 on Coronavirus disease 2019 (COVID-19), and resources from World Health Organisation were analyzed in order to have an understanding of the clinical characteristics, transmission dynamics, virology, diagnostic possibilities, prevention, management approach, controversies and impact of COVID-19 on the healthcare workforce. | 2020-06-03 |
| 32476306 | One month after diagnosis, she complained about hyposmia and hypogeusia two days before the seronegative conversion of SARS-CoV-2, which were confirmed by a neurological examination. | 2020-06-09 |
| 32476394 | In this regard, early diagnosis, including on the basis of symptoms from ENT organs, is crucial. […] However, it is in children in the epidemic aspect that early diagnosis of infection and understanding of its key symptoms is of utmost importance. | 2020-06-05 |
| 32476600 | Without a vaccine or proven therapeutic options in COVID-19, the World Health Organization (WHO) recommends a combination of measures: rapid diagnosis and immediate isolation of cases; rigorous contact tracing; and precautionary self-isolation of close contacts to curb the spread of COVID-19. | 2020-06-01 |
| 32476607 | Molecular diagnosis of the disease is typically performed via nucleic acid-based detection of the virus from swabs, sputum or bronchoalveolar lavage fluid (BALF). | 2020-06-02 |
| 32476644 | In this review, we will address the potential challenges associated with managing ALL patients during the COVID-19 infection pandemic with suggestions of some practical approaches, focusing on screening asymptomatic ALL patients, diagnostic and response evaluation and choice of chemotherapy in different scenarios and setting and use of hematopoietic stem cell transplantation (HSCT). | 2020-06-03 |
| 32477618 | In this publication produced in response to the pandemic, we provide information regarding risk assessment of home reporting of digital slides, summarize available information on specifications for home reporting computing equipment, and share access to a novel point-of-use quality assurance tool for assessing the suitability of home reporting screens for digital slide diagnosis. | 2020-06-04 |
| 32477912 | With reference to the diagnostic criteria in existing pediatric guidelines, we have further improved the triage screening questionnaire for children with fever in our hospital. […] According to the situation in our city and hospital, an evaluation questionnaire that is suitable for use with children in our hospital has been formulated to achieve the goals of early detection, isolation, diagnosis, and treatment. | 2020-06-04 |
| 32478445 | Eight pregnant women with a diagnosis of COVID-19 confirmed by nasal/throat real-time reverse transcription polymerase chain reaction testing who underwent point-of-care LUS examinations after routine obstetric ultrasound are described. | 2020-06-19 |
| 32478543 | Researchers have long examined grief-related reactions to the diagnosis of a loved one with a terminal illness, including preloss grief (PLG), which is the experience of grief symptoms prior to the loss of a loved one. | 2020-06-04 |
| 32478562 | OBJECTIVE. The purpose of this article is to systematically review and meta-analyze the diagnostic accuracy of chest CT in detecting coronavirus disease (COVID-19). MATERIALS AND METHODS. MEDLINE was systematically searched for publications on the diagnostic performance of chest CT in detecting COVID-19. […] Methodologic quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool. […] The included studies were statistically homogeneous in their estimates of sensitivity (p = 0.578) and statistically heterogeneous in their estimates of specificity (p < 0.001). CONCLUSION. Diagnostic accuracy studies on chest CT in COVID-19 suffer from methodologic quality issues. | 2020-06-01 |
| 32479412 | We aimed to understand whether oropharyngeal swab (OPS), saliva, and dried blood spot (DBS) specimens collected by participants at home and mailed to a laboratory were sufficient for use in diagnostic and serology tests of SARS-CoV-2. | 2020-06-26 |
| 32479680 | Further studies are needed to delineate the diagnostic and prognostic value of such cutaneous manifestations. | 2020-06-19 |
| 32479758 | However, the interpretation of test results depends on many variables and factors, including sensitivity, specificity, potential cross-reactivity and cross-protectivity; the diagnostic value of antibodies of different isotypes, the use of antibody testing in identification of acutely ill patients or in epidemiological settings. | 2020-06-03 |
| 32479787 | We did a retrospective, multicentre, cohort study of 205 patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and with a pathological diagnosis of a malignant tumour in nine hospitals within Hubei, China, from Jan 13 to March 18, 2020. | 2020-06-04 |
| 32479829 | In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28-2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65-3·22], p<0·0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2·35 [1·57-3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01-2·39], p=0·046), emergency versus elective surgery (1·67 [1·06-2·63], p=0·026), and major versus minor surgery (1·52 [1·01-2·31], p=0·047). | 2020-06-04 |
| 32479911 | For prompt diagnosis and prevention of transmission, clinicians should consider COVID-19 in patients with similar presentation. | 2020-06-27 |
| 32479921 | Our findings implicate that the differential diagnosis of acute kidney injury in COVID-19-infected patients should include kidney infarction, which may have important preventive and therapeutic implications. | 2020-06-22 |
| 32480215 | Therefore, in the present scenario of COVID-19 pandemic, differential diagnosis resulting positive for common respiratory pathogen(s) should not exclude testing of SARS-CoV-2. | 2020-06-26 |
| 32480420 | Access to health care may be difficult or limited, diagnosis of AL amyloidosis may be delayed with detrimental consequences, treatment administration may need modification. | 2020-06-19 |
| 32481381 | The patient’s postoperative pathological diagnosis was squamous cell carcinoma of the right lower lung. […] We are the first to report the diagnosis and treatment process of patients with COVID-19 during perioperative period of lobectomy. | 2020-06-15 |
| 32482249 | Severe acute respiratory syndrome-CoV-2 was not detected in semen after a median of 31 days (interquartile range, 29-36 days) from COVID-19 diagnosis. […] Severe acute respiratory syndrome-CoV-2 was not detected in the semen of patients recovering from COVID-19 1 month after COVID-19 diagnosis. | 2020-06-10 |
| 32482336 | Surgical backlog (58.6%), delayed cancer diagnosis (43.2%) and re-establishing normal care with delayed patient (37.8%) were identified as the top 3 challenges after COVID-19 has abated. | 2020-06-05 |
| 32482542 | This particular case is being reported to provide a reference and guidance for the diagnosis and management of COVID-19 in AOSC. | 2020-06-05 |
| 32482591 | This review summarizes the emergence of SeACoV and updates the research progress made from 2017 to early 2020, mainly focusing on the etiology, epidemiology, evolutionary perspective, potential for interspecies transmission, pathogenesis and diagnosis. | 2020-06-27 |
| 32482633 | The Luminex NxTAG CoV Extended Panel is a high-throughput FDA emergency use authorized molecular diagnostic assay for SARS-CoV-2 detection. […] This system targets three genes (ORF1ab, N and E gene) of SARS-CoV-2, ORF1ab region of SARS-CoV and ORF5 region of MERS-CoV.In this study, we evaluated the diagnostic performance of this system with nasopharyngeal swab specimens of 214 suspected COVID-19 patients in Hong Kong. […] Overall the E gene target of the NxTAG panel demonstrated the highest sensitivity among the three SARS-CoV-2 targets while the N gene targets demonstrated the least.In conclusion, the NxTAG CoV Extended Panel is simple to use and it has high diagnostic sensitivity and specificity to SARS-CoV-2 in nasopharyngeal specimens. we recommend this diagnostic system for high-throughput COVID-19 screening in the community. | 2020-06-02 |
| 32482888 | The COVID-19 pandemic has had a major impact on diagnostic laboratories, particularly those handling cell and tissue specimens. | 2020-06-24 |
| 32482926 | We have also discussed the diagnosis, treatment and preventive measures that are currently being employed for controlling further spread of the virus. | 2020-06-03 |
| 32483236 | Given the ongoing SARS-CoV-2 pandemic, identification of immunogenic targets against the coronavirus spike glycoprotein will provide crucial advances towards the development of sensitive diagnostic tools and potential vaccine candidate targets. | 2020-06-15 |
| 32483515 | There is widespread agreement that reliable, fast, and easy-to-produce diagnostic testing methods that have high sensitivity and specificity are essential for guiding appropriate responses to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak. […] We discuss the value and limitations of these approaches and suggest directions for future research that can advance the understanding of diagnostic methods. | 2020-06-05 |
| 32483523 | Two hundred and sixty-six (67.7%) aimed at therapeutic effect, others were for prevention, diagnosis, prognosis, etc. | 2020-06-05 |
| 32483524 | A narrow diagnostic approach where only febrile patients with pulmonary symptoms are evaluated for a COVID-19 diagnosis will result in many missed diagnoses; so it is important that physicians are familiar with atypical and rare presentations of COVID-19, such as isolated thrombocytopenia. | 2020-06-05 |
| 32483586 | Detection of SARS-CoV-2 viral RNA is important for the diagnosis and management of COVID-19. | 2020-06-26 |
| 32483687 | During the current context of COVID-19 pandemic, physicians should be aware of wide spectrum of neurological COVID-19 sign and symptoms for early diagnosis and isolation of patients. | 2020-06-05 |
| 32483909 | We describe the first case report of renal allograft infarction in a 46-year-old kidney-pancreas transplant recipient with no prior history of thromboembolism, who presented 26 days after diagnosis of COVID-19. | 2020-06-24 |
| 32484225 | While we conducted real-time reverse transcriptase polymerase chain reaction SARS-CoV-2 laboratory tests for soldiers who were suspected to have COVID-19 (those presenting with compatible signs and symptoms after having been exposed to a confirmed COVID-19 patient), we were not able to screen healthy populations, nor did we have serum antibody serologic tests available during the study period. | 2020-06-26 |
| 32484380 | We aim to review the current evidence regarding the diagnosis and management of head and neck cancer, with an emphasis on the role of the multidisciplinary team (MDT) during a pandemic. | 2020-06-02 |
| 32484453 | The receiver operating characteristic curve was applied to determine the best diagnostic thresholds for laboratory results, and principal component analysis was used to screen the major risk factors. | 2020-06-26 |
| 32484930 | Diagnostic tests, laboratory examinations, clinical findings and computed tomography of the thorax imaging results were evaluated. […] Eosinophil values were quite low at the time of diagnosis (10±17.06), but increased significantly post-tocilizumab (155.33±192.69). | 2020-06-19 |
| 32485157 | Diagnostic sensitivity and specificity, positive and negative likelihood ratios were evaluated using manufacturers’ and optimized thresholds. […] Diagnostic sensitivities and specificities were above 93.8% and 85.9%, respectively for all CLIA assays. […] Redefined thresholds, in addition, improved the overall inter-assay agreement, paving the way to a better harmonization of serologic tests. | 2020-06-27 |
| 32485197 | Patients in other groups were cohorted when isolation capacity was limited with additional interventions to reduce transmission. 93 patients were evaluated with 79 (85%) receiving a COVID-19 diagnosis during their admission. […] Of those without a COVID-19 diagnosis: 10 were initially triaged to Category A; 0 to B; 1 to C and 4 to D. | 2020-06-05 |
| 32485299 | The most common AGPs were diagnostic flexible laryngoscopy, diagnostic nasal endoscopy, and flexible laryngoscopy with stroboscopy. | 2020-06-26 |
| 32485335 | To evaluate the diagnostic accuracy and the imaging features of routine admission chest X-ray in patients suspected for novel Coronavirus 2019 (SARS-CoV-2) infection. | 2020-06-26 |
| 32485418 | A number of pressing issues were identified by this review, including defining the true incidence of VTE in COVID patients, developing algorithms to identify those susceptible to develop thrombotic complications and severe disease, determining the role of biomarkers and/or scoring systems to stratify patients’ risk, designing adequate and feasible diagnostic protocols for PE, establishing the optimal thromboprophylaxis strategy, and developing uniform diagnostic and reporting criteria. | 2020-06-24 |
| 32485473 | Several qPCR kits are available for SARS-CoV-2 diagnosis, mostly lacking of evaluation due to covid19 emergency. […] Validation studies should be implemented for any SARS-CoV-2 RT-qPCR commercial kit to prevent unreliable diagnosis. | 2020-06-18 |
| 32485618 | Ensuring accurate diagnosis is essential to limit the spread of SARS-CoV-2 and for the clinical management of COVID-19. […] Although real-time reverse transcription polymerase chain reaction (RT- qPCR) is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such as requirement of special equipment and skilled staff limit the use of these time-consuming molecular techniques. […] Recently, several easy to perform rapid antigen detection tests were developed and recommended in some countries as the first line of diagnostic. […] Unfortunately, the overall poor sensitivity of the COVID-19 Ag Respi-Strip does not allow using it alone as the frontline testing for COVID-19 diagnosis. | 2020-06-26 |
| 32485620 | The EUROIMMUN Anti-SARS-CoV-2 ELISA Assay demonstrated good sensitivity for detection of IgA and excellent sensitivity for detection of IgG antibodies from samples collected ≥4 days, after COVID-19 diagnosis by PCR. | 2020-06-26 |
| 32485859 | Mental health problems were assessed with the Post-Traumatic Stress Disorders (PTSD) Checklist for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), the Center for Epidemiological Studies Depression inventory, and the Pittsburgh Sleep Quality Index. | 2020-06-09 |
| 32486364 | These viruses have been scrutinized using rapid diagnostic detection and therapeutic interventional options against the caused infections including vaccine development for prevention and control. […] This perspective review expounds recent nanoscience advancements for the detection and treatment of viral infections with focus on coronaviruses and encompasses nano-based formulations and delivery platforms, nanovaccines, and promising methods for clinical diagnosis, especially regarding SARS-CoV-2. | 2020-06-03 |
| 32486556 | This article summarized the understanding of the etiology, pathogenesis, epidemiology, clinical characteristics, diagnosis, treatment, rehabilitation, and prevention and control measures of COVID-19 based on the available data and anti-epidemic experience in China. | 2020-06-04 |
| 32487005 | The acquired breathing sounds can be analyzed using advanced signal processing and analysis in tandem with new deep/machine learning and pattern recognition techniques to separate the breathing phases, estimate the lung volume, oxygenation, and to further classify the breathing data input into healthy or unhealthy cases. | 2020-06-03 |
| 32487159 | Herein, we summarize the virology, epidemiology, clinical manifestations, diagnosis, treatment and prevention of SARS-CoV-2, and hope that countries can control the outbreak as soon as possible to minimize the loss. | 2020-06-17 |
| 32487681 | SARS-CoV-2 serological tests are a subject of intense interest and have the potential to significantly enhance the diagnostic capability of healthcare services in the current pandemic. | 2020-06-12 |
| 32487868 | The aim of this position paper is to provide clinical recommendation regarding the execution of imaging investigations for the cardiac diagnostic work-up of paediatric patients with suspected or confirmed infection. | 2020-06-17 |
| 32487907 | Medical services can be apportioned as procedural care (eg, surgery, radiology, or laboratory testing and others) or cognitive care, also known as Evaluation and Management (E/M) services, in which the provider formulates an assessment and plan after obtaining information from the patient’s history, examination, and diagnostic tests.Providing a medical opinion and plan using the telephone as the technology that links the provider and the patient is an example of a non-face-to-face E/M service. | 2020-06-11 |
| 32488413 | Direct contact to patients may have to be reduced in favor of telephone calls or video conferences, so that new techniques in diagnosing and treating patients have to be established to guarantee patient safety. | 2020-06-05 |
| 32488493 | Techniques to minimize aerosolization and appropriate personal protective equipment may help reduce the risk to healthcare workers in the operating room. | 2020-06-05 |
| 32489022 | In the previous research, our laboratory established a mouse model combining disease with syndrome of human coronavi-rus pneumonia with pestilence attacking the lung syndrome, based on the national traditional Chinese medicine clinical classification of Novel Coronavirus Infected Pneumonia Diagnosis and Treatment Plan. | 2020-06-05 |
| 32489023 | This model is suitable for simulating traditional Chinese medicine treatment of common disease syndromes in Novel Coronavirus Pneumonia Diagnosis and Treatment program(trial implementation of the sixth edition). | 2020-06-05 |
| 32489024 | According to 2 prescriptions in the Protocol for the diagnosis and treatment of coronavirus disease 2019(7th edition)and 9 prescriptions in Traditional Chinese medicine prescriptions for treating blight, 959 and 1 047 potential ingredients were obtained as the inhibitors of VEGFR and FGFR respectively with the screening thres-hold set as eighty percent of the docking score of the initial ligands. | 2020-06-05 |
| 32489030 | The analysis and utilization of clinical scientific research data is an effective means to promote the progress of diagnosis and treatment, and a key step in the development of medical sciences. […] During the epidemic of coronavirus disease 2019(COVID-19), how to transform the limited diagnostic data into clinical research resources has attracted much attention. | 2020-06-05 |
| 32489502 | We discussed measures required to limit the spread of infection, as well as summarized the guidance as per the Centers for Disease Control and Prevention (CDC), American Society of Nephrology (ASN), American Society of Diagnostic and Interventional Nephrology (ASDIN) and the Vascular Access Society of the Americas (VASA). | 2020-06-05 |
| 32489507 | The clinicians should be aware of the sensitivity and specificities of these tests which can have grave implications on the patient and community if the diagnosis is missed just based on the laboratory tests due to the highly contagious nature of the disease. | 2020-06-05 |
| 32489708 | Furthermore, there was also a negative correlation between lymphocytes (r = -0.54, p = 0.038) or T cells (r = -0.55, p = 0.034) at diagnosis and the nucleic acid-positive duration, separately. | 2020-06-05 |
| 32489724 | Based on the case presented and other cases, understanding the pathways of virus neuroinvasion is necessary to help recognize possible pathologically related consequences of infection and to evaluate new diagnostic and management approaches that will help improve SARS-CoV-2 infection treatment and control. | 2020-06-05 |
| 32489928 | The COVID-19 pandemic seriously threatens the lives of the general public and poses momentous challenges to all medical workers, including those engaged in interventional radiology, who play an important role in the diagnosis and treatment of various diseases. […] To further standardize the prevention and control of nosocomial infections and ensure the safety of doctors and patients, the Chinese Society of Interventional Radiology (CSIR) organized multidisciplinary experts in the field of interventional radiology in China to prepare an “Expert Consensus” elaborating and summarizing the protective strategies and suggestions for medical workers in the field of interventional radiology when they engage in interventional diagnosis and treatment activities against the background of novel coronavirus infection control. […] The key points include the following: (I) non-emergency interventional diagnosis and treatment should be suspended while work is ongoing to prevent and control the spread of COVID-19; (II) protective measures should be taken according to the appropriate level designated for COVID-19 infection prevention and control; (III) patients should take measures to protect themselves when they want to see a doctor, including accessing outpatient services online and other relevant channels of consultation. | 2020-06-05 |
| 32489929 | However, its role as a screening and diagnostic tool in COVID-19 remains to be clarified. […] This article provides a systematic review and meta-analysis of the current literature on chest CT imaging findings with the aim of highlighting the contribution and judicious use of CT in the diagnosis of COVID-19. […] Chest imaging abnormalities associated with COVID-19 were extracted from the eligible studies and diagnostic value of CT in detecting these abnormal changes was compared between studies consisting of both COVID-19 and non-COVID-19 patients. […] Despite widespread use of CT in the diagnosis of COVID-19 patients based on the current literature, CT findings are not pathognomonic as it lacks specificity in differentiating imaging appearances caused by different types of pneumonia. […] Use of CT as a first-line diagnostic or screening tool in COVID-19 is not recommended. | 2020-06-05 |
| 32490846 | These tweets were grouped into five main categories including first- and secondhand reports of symptoms, symptom reporting concurrent with lack of testing, discussion of recovery, confirmation of negative COVID-19 diagnosis after receiving testing, and users recalling symptoms and questioning whether they might have been previously infected with COVID-19. | 2020-06-15 |
| 32491091 | We estimated the proportion and number of adults (≥ 18 years) at risk of severe Covid-19 by sex, educational level, race/ethnicity, and state based on the presence of one or more of the following risk factors: age ≥ 65 years or medical diagnosis of cardiovascular disease, diabetes, hypertension, chronic respiratory disease, cancer, stroke, chronic kidney disease and moderate to severe asthma, smoking status, and obesity. | 2020-06-11 |
| 32491214 | In 1991 and 2009 the Italian sentinel surveillance system was established, consisting in 25 public centers (12 clinical, 13 laboratories) on the national field for diagnosis, treatment and data transmission to the INIH4 . | 2020-06-19 |
| 32491257 | Chest computed tomography (CT) has shown tremendous clinical potential for screening, diagnosis, and surveillance of COVID-19. | 2020-06-19 |
| 32491306 | In here we present a comparison among the current diagnostic tools and kits being used to test Brazilian population. | 2020-06-03 |
| 32491919 | To supplement conventional diagnostic testing, which is constrained by capacity, cost, and its one-off nature, innovative tactics for public health surveillance, such as crowdsourcing digital wearable data and monitoring sewage sludge, might be helpful. | 2020-06-19 |
| 32492197 | In this review article, we have collected the latest data about characteristics, pathogenesis, clinical manifestations, and diagnostic methods of SARS-CoV-2. | 2020-06-19 |
| 32492209 | The virus was detected for diagnosis. | 2020-06-19 |
| 32492485 | 27.4% of well-documented asymptomatic cases developed delayed symptoms after the pathogenic diagnosis. 60% of asymptomatic cases demonstrated findings of pneumonia on the initial chest CT, including well-recognized features of coronavirus disease-19. | 2020-06-08 |
| 32492531 | The gold-standard COVID-19 diagnosis relies on detecting SARS-CoV-2 using RNA purification and one-step retrotranscription and quantitative PCR (RT-qPCR). […] Our findings provide valuable options to overcome any supply chain issue and help to increase the throughput of diagnostic tests, thereby complementing standard diagnosis. | 2020-06-28 |
| 32492533 | Early diagnosis and supportive care are of great importance for the elderly patients of COVID-19. | 2020-06-05 |
| 32492721 | Saliva is proving to be a promising noninvasive sample specimen for the diagnosis of COVID-19, thus helping to monitor the infection and prevent it from further spreading by prompt isolation. | 2020-06-03 |
| 32492743 | Low-threshold diagnostic testing and rapid detection of infection chains remain essential for better control of the pandemic. | 2020-06-09 |
| 32492760 | This was made possible by increasing availability of diagnostic molecular tests in several formats, from laboratory based traditional, RT-PCR methods to near patient testing rapid point of care PCR tests. | 2020-06-19 |
| 32492991 | The diagnosis of SARS-CoV-2 infection is crucial for medical and public health reasons, to allow the best treatment of cases and the best control of the pandemic. […] Rapid serology tests are useful for the diagnosis of patients with COVID-19 (mainly IgG detection) and may also be correlated with the severity of the infection (based on IgM detection). | 2020-06-04 |
| 32493473 | Patients with moderate to severe ARDS as defined by the Berlin definition, receiving invasive mechanical ventilation and with a diagnosis of COVID-19 based on clinical diagnosis or PCR test will be eligible. | 2020-06-10 |
| 32493475 | Inclusion Criteria: Male or female participants ≥ 18 and ≤ 80 years of age.Healthcare workers from the public and private Spanish hospital network at risk of SARS-CoV 2 infection.Not having a previous COVID19 diagnosis.Understanding the purpose of the trial and not having taken any pre-exposure prophylaxis (PrEP) including HIV PrEP from March 1st 2020 until study enrolment.Having a negative SARS-CoV 2 reverse-transcription PCR (RT-PCR) result or a negative serologic rapid test (IgM/IgG) result before randomization.Premenopausal women must have a negative urinary pregnancy test in the 7 days before starting the trial treatment.Premenopausal women and males with premenopausal couples must commit to using a high efficiency anticonceptive method. […] Number of SARS-CoV-2 (COVID-19) symptomatic infections confirmed by polymerase chain reaction (PCR) test or serologic test or according to each centre diagnosis protocol. | 2020-06-10 |
| 32493478 | Had a close contact of a person (index) with known PCR-confirmed SARS-CoV-2 infection or index who is currently being assessed for COVID-19 Close contact is defined as: a.Household contact (i.e., residing with the index case in the 14 days prior to index diagnosis or prolonged exposure within a residence/vehicle/enclosed space without maintaining social distance)b.Medical staff, first responders, or other care persons who cared for the index case without personal protection (mask and gloves)4. | 2020-06-10 |
| 32493494 | 1)Intervention: (n = 225): One 200 mg hydroxychloroquine sulfate coated tablet once daily for two months.2)Comparator (control group) (n = 225): One hydroxychloroquine placebo tablet (identical to that of the drug) once daily for two months MAIN OUTCOMES: The primary outcome of this study will be to evaluate: number and percentage of healthcare personnel presenting symptomatic and asymptomatic infection (see “Diagnosis of SARS CoV2 infection” below) by the SARS-Cov2 virus during the study observation period (8 weeks) in both treatment arms;number and percentage of healthcare personnel in each group presenting with Pneumonia with severity criteria (Curb 65 ≥2) and number and percentage of healthcare personnel requiring admission to the Intensive Care Unit (ICU) in both treatment arms. […] DIAGNOSIS OF SARS COV2 INFECTION: Determination of IgA, IgM and IgG type antibodies against SARS-CoV-2 using the Anti-SARS-CoV-2 ELISA kit (EUROIMMUN Medizinische Labordiagnostika AG, Germany) every two weeks. | 2020-06-10 |
| 32493514 | Simultaneous participation in other interventional trials (except for participation in COVID-19 trials) which could interfere with this trial; simultaneous participation in registry and diagnostic trials is allowed15. | 2020-06-10 |
| 32493604 | The SARS-Cov-2 pandemic influenced the time of diagnosis of appendicitis, as well as its course, and mean hospital stay. […] As a result of the significant circumstances, delaying diagnosis and treatment of AA during SARS-Cov-2 pandemic, inappropriate management of this common surgical disorder has been noticed. | 2020-06-06 |
| 32494567 | In this review the SARS-CoV-2 morphology, pathogenic mechanism, similarities and differences between SARS-CoV and Middle East Respiratory Syndrome and severe acute respiratory syndrome, transmission mode, diagnosis, treatment, and preventive measures were investigated. | 2020-06-06 |
| 32495574 | In these cases, patients were treated with other integrated Chinese and Western medicines regimens in the recommended Matrine and Sodium Chloride Injection diagnosis and treatment regimen. | 2020-06-08 |
| 32495580 | Based on the guideline from the Diagnosis and Treatment Plans for COVID-19(trial seventh edition), taking the recommended drugs as examples, by Western medicine, traditional Chinese medicine, Chinese herbal injection and integrated traditional Chinese and Western medicine, the study analyzed the basic characteristics of recommended drugs for cardiac injury by means of literature review and bioinformatics methods, and summarized cardiac adverse reactions, toxicity mechanisms, combined pharmacotherapy, special population and drug monitoring, focusing on the clinical manifestations, toxic components, targets and regulatory mechanisms of drug-induced cardiac injury. | 2020-06-08 |
| 32495582 | The scientific study conclusions aim to give feedbacks to clinical diagnosis and treatment regimens. […] It is suggested that scientific experimental design, rigorous collection and scientific data analysis shall be conducted to reflect the therapeutic value of traditional Chinese medicine, so that the study results could be adopted and shared, and become the scientific evidence for China and even the global to republish the diagnosis and treatment regimens. | 2020-06-08 |
| 32495826 | We conducted a national survey among IBD gastroenterologist members of the Spanish Working Group on Crohn’s Disease and Colitis regarding changes of practice, IBD treatments, and diagnosis and treatment of COVID-19. […] In addition, 7.5% of IBD units made a COVID-19 diagnosis through polymerase chain reaction and/or chest x-ray.Modifications in IBD treatment and treatment recommended for COVID-19 are also discussed. […] We report a representative national survey of changes made in the structure, diagnosis of COVID-19, and modifications in IBD treatments within IBD units. | 2020-06-26 |
| 32495915 | In an osteoporosis clinic, we advocate the following suggestions to prevent and control osteoporosis during the pandemic period: (1) specialized diagnosis and treatment techniques for osteoporosis patients in the outpatient care, including enhancing the prevention for outpatient medical staff, strengthening awareness of COVID-19 prevention, strictly screening outpatients with COVID-19 infection, and insistent administration of anti-osteoporosis drugs during outbreaks; (2) home prevention for osteoporosis patients including keeping windows open, exposing them to sunlight, supplementing them with enough protein, exercising regularly, and administrating calcium supplements; and (3) simplifying the follow-up and evaluation of osteoporosis using online platforms. | 2020-06-10 |
| 32495921 | Diagnosis is being carried out by collecting a nasopharyngeal swab or sputum specimen for detection of SARS-CoV-2 RNA by reverse-transcription polymerase chain reaction (RT-PCR). | 2020-06-10 |
| 32495923 | The early diagnosis and management of the disease remains a major challenge. […] In this review, we aim to summarize the updated epidemiology, causes, clinical manifestation and diagnosis, as well as prevention and control of the novel coronavirus SARS-CoV-2. | 2020-06-10 |
| 32496207 | A number of studies about disease diagnosis and treatment have been carried out, and many clinically proven effective results have been achieved. […] This issue becomes even more serious if the knowledge for diagnosis and treatment is updated rapidly as is the case for COVID-19. […] This study aims to develop a shared data model based on the openEHR modeling approach to improve the interoperability among systems for the diagnosis and treatment of COVID-19. […] The latest Guideline of COVID-19 Diagnosis and Treatment in China was selected as the knowledge source for modeling. […] First, the guideline was analyzed and the data items used for diagnosis and treatment, and management were extracted. | 2020-06-17 |
| 32496242 | The mainstay of the diagnosis is a reverse-transcription polymerase chain reaction assay to detect SARS-CoV-2 RNA. […] The accurate diagnosis is contingent on appropriate specimen choice, time of collection, and assay employed. […] In this commentary, we highlight the role of laboratory diagnostic tests used in the different stages of India’s COVID-19 pandemic response. | 2020-06-17 |
| 32496357 | Diagnostic workup, clinical course, immunosuppression/antiviral management and immediate outcomes are described. […] Mean age at diagnosis was 54.8 ± 10.9 years. […] Only 1 mortality (4.8%) to date, in a critically-ill heart/kidney patient who had been in the ICU prior to diagnosis. | 2020-06-19 |
| 32496429 | The aim of this study was to compare the effectiveness of different barrier enclosure techniques during tracheal intubation and extubation. | 2020-06-09 |
| 32496734 | The aim of this study is to investigate whether there exists a relationship between the blood groups of the patients and risk of SARS-CoV-2 infection and the clinical outcomes in COVID-19 patients. 186 patients with PCR confirmed diagnosis of COVID-19 were included in this study. | 2020-06-04 |
| 32496919 | Accurate serologic tests to detect host antibodies to severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) will be critical for the public health response to the coronavirus disease 2019 pandemic. […] Many use cases are envisaged, including complementing molecular methods for diagnosis of active disease and estimating immunity for individuals. | 2020-06-20 |
| 32496988 | Scanning patient’s lungs to detect a Coronavirus 2019 (COVID-19) may lead to similar imaging with other chest diseases that strongly requires a multidisciplinary approach to confirm the diagnosis. […] There have been few works regarding detection of the coronavirus but there are many cases where it can be misclassified as some techniques do not provide any goodness if it can only identify type of diseases and ignore the rest. | 2020-06-04 |
| 32497090 | RT-PCR was inferior to CT-based diagnosis in 31.7% (26/79) of cases. | 2020-06-10 |
| 32497191 | Our study suggests the potential value of the gut microbiota as a diagnostic biomarker and therapeutic target for COVID-19, but further validation is needed. | 2020-06-26 |
| 32497283 | All patients with a presumed diagnosis of COVID-19 were routinely screened for influenza. | 2020-06-04 |
| 32497344 | Most probable diagnosis was COVID-19 induced immune thrombocytopenia (ITP) and high dose intravenous immunoglobulin (IVIg) treatment generated a good response. | 2020-06-19 |
| 32497413 | Then, for each nursing diagnosis, outcomes aligned with all components of the diagnosis were categorized and a list of nursing interventions was selected. […] For the nursing diagnosis Deficient Community Health, eight nursing outcomes and 12 nursing interventions were selected. […] In comparison for the nursing diagnosis, Ineffective Community Coping, nine nursing outcomes and 18 nursing interventions were identified. | 2020-06-19 |
| 32497751 | Delayed diagnosis, lack of cancer awareness, low adherence to treatment, and unequal or limited access to treatment are among the challenging factors of cancer management in developing countries. | 2020-06-26 |
| 32497809 | In the context of the Covid-19 pandemic, the development and validation of rapid and easy-to-perform diagnostic methods are of high priority. […] Diagnostic accuracy was determined in comparison to SARS-CoV-2 real time (RT)-PCR. […] Overall sensitivity and specificity were 93.9% (CI95% 86.5-97.4) and 100% (CI95% 92.1-100), respectively, with a diagnostic accuracy of 96.1% and Kappa coefficient of 0.9. […] The assay has the potential to become an important tool for early diagnosis of SARS-CoV-2, particularly in situations with limited access to molecular methods. | 2020-06-06 |
| 32498097 | While the risk of venous thromboembolism (VTE) appears to be higher in patients requiring intensive care unit support compared to those admitted to general wards, recent autopsy findings and data on the timing of VTE diagnosis relative to hospitalization clearly suggest that thromboembolic events also contribute to morbidity and mortality in the ambulatory setting. | 2020-06-04 |
| 32498262 | The mean time from symptom onset to diagnosis and admission was 2.6 and 3.5 days, respectively. […] Despite the high-risk conditions associated with worse outcomes, patients on HD did not exhibit extremely poor overall COVID-19 outcomes perhaps due to early diagnosis, prompt hospitalization, and antiviral therapy. | 2020-06-05 |
| 32498686 | Components of immune system, such as antibodies, can also be used to develop sensitive and specific diagnostic methods as well as novel therapeutic agents. […] We also describe the diagnostic methods being used for COVID-19 identification and summarize the current status of various therapeutic strategies, including vaccination, being considered for treatment of the disease. | 2020-06-10 |
| 32498762 | Diagnosis is based on epidemiological, clinical and imaging features and confirmed by nucleic acid testing. | 2020-06-05 |
| 32499073 | No homogeneous national health surveillance/screening programs are ongoing or have been conceived to test susceptible population among children/healthcare workers in preparation of coming down to routinely daily activities, and diagnostic strategies are not completely accurate in children. | 2020-06-08 |
| 32499236 | At present, there are limited reports on definite diagnosis of myocarditis caused by SARS-CoV-2 in humans and limited demonstration of the virus in the myocardium. | 2020-06-05 |
| 32499303 | Data on demographics, COVID-19 diagnosis, famotidine use, drug-related side effects, temperature measurements, oxygen saturations and symptom scores were obtained using questionnaires and telephone interviews. | 2020-06-24 |
| 32499983 | In this review, we discuss the background, epidemiology, possible pathophysiology, clinical presentation, and diagnostic studies related to SARS-CoV-2 infection. | 2020-06-07 |
| 32500327 | This manuscript highlights the importance of endoscopy in daily ENT clinical practice, which is a pivotal procedure in the diagnosis of many head and neck pathologies. | 2020-06-08 |
| 32500432 | The interruption of CRC prevention may lead to a delayed diagnosis of CRC, possibly in a more advanced stage. | 2020-06-08 |
| 32500509 | An early diagnosis of COVID-19 is crucial for disease treatment and control of the disease spread. […] Real-time reverse-transcription polymerase chain reaction (RT-PCR) demonstrated a low sensibility; therefore chest computed tomography (CT) plays a pivotal role not only in the early detection and diagnosis, especially for false negative RT-PCR tests, but also in monitoring the clinical course and in evaluating the disease severity. | 2020-06-25 |
| 32500510 | The current COVID-19 outbreak is requiring a tremendous effort not only regarding the diagnostic and therapeutic approach but also in terms of global management of the delivered care. […] To optimize the diagnostic pathway during the current COVID-19 outbreak, the hospital administration of our tertiary center applied a highly structured framework assigning specific tasks to the different units composing the Department of Imaging. […] In particular, since the beginning of the pandemic, a mobile CT scanner in a truck was rented and became operative for all patients with a confirmed diagnosis of COVID-19 and another CT was assigned for all suspected cases. […] Thus, according to the experience gained in our center, we recommend to all hospital administrations facing the COVID-19 outbreak to promptly adapt their resources, creating precise and safe pathways for their diagnostic units. | 2020-06-25 |
| 32500571 | We investigated whether there had been a similar reduction in urgent cancer referrals (known in England as the Two Week Wait (TWW) pathway) and subsequent diagnosis of skin cancer in our dermatology service. | 2020-06-19 |
| 32500849 | Thus, a search for modalities that can expedite and improve the diagnosis and management of this entity is underway. […] Recent data suggested the utility of lung ultrasound (LUS) in the diagnosis of COVID-19 by detecting an interstitial pattern (B-pattern). […] The finding from our review highlights the potential role of this modality in the triage, diagnosis, and follow-up of COVID-19 patients. […] A sizable diagnostic accuracy study comparing LUS, computed tomography scan, and COVID-19-specific tests is warranted to further test this finding and to delineate the diagnostic and prognostic yield of each of these modalities. | 2020-06-05 |
| 32500987 | However, in the laboratory diagnosis of SARS-CoV-2 infections, in addition to genetic tests, serological methods can also be used to detect specific antibodies of the IgM, IgG and IgA class produced after contact with antigens or to detect viral antigen. […] Currently, a number of rapid immunochromatographic, chemiluminescent and ELISA immunoassay tests developed by different manufacturers for the diagnosis of COVID-19 are available on the market. […] Despite this fact, so far there is no WHO or ECDC recommendations or even reliable research regarding the usefulness of serological investigations in the laboratory diagnosis of infections caused by SARS-CoV-2. | 2020-06-09 |
| 32501019 | Self-collection of upper respiratory tract specimen for diagnostic purposes is not new. | 2020-06-09 |
| 32501367 | The aim of this study is to provide a critical appraisal of the safety information regarding chloroquine treatment and to apply simulation techniques to unveil relationships between the observed serious adverse events and overdosing, as well as to propose optimized dosage regimens. | 2020-06-08 |
| 32501382 | In this article, we provide a brief review for Orthopedic surgeons as regard COVID-19 virus microbiology, epidemiology, clinical picture, and diagnosis. | 2020-06-08 |
| 32501411 | A lot of serological diagnostic kits have been proposed on the market but validation studies have not been published for many of them. | 2020-06-08 |
| 32501424 | In this paper, we have trained several deep convolutional networks with introduced training techniques for classifying X-ray images into three classes: normal, pneumonia, and COVID-19, based on two open-source datasets. […] In this research, we introduce some training techniques that help the network learn better when we have an unbalanced dataset (fewer cases of COVID-19 along with more cases from other classes). | 2020-06-16 |
| 32501429 | The novel coronavirus disease 2019, a pandemic of global concern, caused by the novel severe acute respiratory syndrome coronavirus 2 has severely revealed the need for public monitoring and efficient screening techniques. | 2020-06-08 |
| 32501535 | The diagnostic specificity was 100% (95% CI: 92.9%-100%). | 2020-06-19 |
| 32501805 | Data analysis will include parametric and nonparametric techniques, focusing on primary outcomes (ie, stress, anxiety, and depressive symptoms) and metrics of use, including the number of subscribers and user satisfaction. | 2020-06-23 |
| 32502091 | It is critical for nuclear medicine physicians to develop diagnostic skills for timely recognition of typical findings of C-19AP on a localizing CT. | 2020-06-22 |
| 32502288 | The COVID-19 pandemic has presented significant challenges for Dermatology services, particularly the diagnosis and management of malignant melanoma (MM). | 2020-06-19 |
| 32502594 | This recognition has led to the urgent need for practical guidance regarding prevention, diagnosis, and treatment of VTE. […] A group of approved panelists developed key clinical questions by using the PICO (Population, Intervention, Comparator, Outcome) format that addressed urgent clinical questions regarding the prevention, diagnosis, and treatment of VTE in patients with COVID-19. | 2020-06-26 |
| 32502645 | We investigated the prevalence of anosmia and ageusia in adult patients with a laboratory-confirmed diagnosis of infection with severe acute respiratory distress syndrome coronavirus-2 (SARS-CoV-2). | 2020-06-25 |
| 32502646 | To assess the diagnostic performance of rapid lateral flow immunochromatographic assays (LFAs) compared with an ELISA and nucleic acid amplification tests (NATs) in individuals with suspected coronavirus disease 2019 (COVID-19). […] There is large variability in diagnostic test performance between rapid LFAs, but overall limited sensitivity and high specificity in acutely admitted patients. | 2020-06-12 |
| 32502693 | Reduced access to primary care, diagnostic and hospital services for diabetes, combined with fear of exposure to the virus in these settings, led to a significant drop in access to usual diabetes care. | 2020-06-28 |
| 32502796 | The estimated time interval between diagnosis and treatment initiation increased for about 20% of institutions. | 2020-06-26 |
| 32502882 | Eligible patients using renin-angiotensin system blockers (ACEI/ARBs) with a confirmed diagnosis of COVID-19 will be randomized to a strategy of continued ACEI/ARB treatment versus temporary discontinuation for 30 days. | 2020-06-26 |
| 32503088 | The authors therefore provide guidance for more careful clinical, diagnostic and epidemiological studies to characterize the manifestations and burden of neurological disease caused by SARS-CoV-2 on behalf of the Infectious Disease Panel of the European Academy of Neurology. | 2020-06-19 |
| 32503298 | This study presents the design of a sophisticated artificial intelligence (AI) chatbot for the purpose of diagnostic evaluation and recommending immediate measures when patients are exposed to nCOV-19. | 2020-06-08 |
| 32503657 | After the first diagnosis and treatment of COVID-19, the nucleic acid test of respiratory specimens such as sputum or nasopharyngeal swabs, has been negative for two consecutive times (sampling time interval of at least 24 hours), in accordance with the COVID-19’s diagnosis and treatment Plan (7th Edition), discharged.3. | 2020-06-08 |
| 32503701 | How to scan addresses the topics of scanning techniques (tailored protocols, right-handed scanning, use of barrier devices) and equipment cleaning and disinfecting. | 2020-06-22 |
| 32503812 | Elevation of initial blood glucose level of critical diagnosis was an independent risk factor for in-hospital mortality in critical cases (HR=1.84, 95% CI 1.14 to 2.98, p=0.013). […] Higher median glucose level during hospital stay or after critical diagnosis (≥6.1 mmol/L) was independently associated with increased risks of progression to critical cases/death among non-critical cases, as well as in-hospital mortality in critical cases. | 2020-06-19 |
| 32503826 | Temporary recommendations are needed that could assist specialists in preventing COVID-19 infection and optimizing resources for diagnosis and treatment of BC patients. | 2020-06-22 |
| 32503959 | These are recommendations from the Indian Association of Gastro Intestinal Endo Surgeons for safe performance of diagnostic and therapeutic endoscopy during the COVID-19 pandemic. | 2020-06-08 |
| 32504135 | LU was performed bedside by a single investigator at the time of diagnosis and every 48 h during the first week following diagnosis. […] We describe the findings of lung ultrasound monitoring during the first week following diagnosis in three neonates with SARS-CoV-2 infection.What is known:• Lung ultrasound (LU) is a useful tool in COVID-19 management in adults. | 2020-06-09 |
| 32504637 | An observational study is ongoing at San Donato Hospital with the aim to evaluate the contribution of MDW in the diagnostic pathway in adult patients entering in the ED setting and tested for SARS-CoV-2. | 2020-06-27 |
| 32504735 | In this study, we evaluated the performance of six CE-marked point-of-care tests (POC) and three ELISA assays for the diagnosis of COVID-19 by exploring seroconversions in hospitalized patients who tested positive for SARS-CoV-2 RNA. […] To achieve an early diagnosis of COVID-19 based on antibody detection, a dual challenge must be met: the immunodiagnostic window period must be shortened and an optimal specificity must be conserved. | 2020-06-19 |
| 32504944 | The COVID-19 Ag (Antigen) Respi-Strip assay is a new immunochromatographic diagnostic tool recently available for antigenic diagnosis of SARS-CoV-2. […] The proposed sensitivity is not higher than 60 %, but its high specificity allows both quick decisions for the management of patients and confirmation by molecular diagnosis for only negative tests. […] Over a period of one month, we compared the negative results obtained with the COVID-19 Ag Respi-Strip kit with those obtained from qRT-PCR performed in a laboratory qualified for the molecular diagnosis of SARS-CoV-2. | 2020-06-26 |
| 32504945 | SARS-CoV-2 infection diagnosis is challenging in patients from 2 to 3 weeks after the onset of symptoms, due to the low positivity rate of the PCR. […] Serologic tests could be complementary to PCR in these situations. […] The aim of our study was to analyze the diagnostic performance of one serologic rapid test in COVID-19 patients. […] Then, we prospectively evaluated the test in 61 patients with clinical diagnosis of pneumonia of unknown etiology that were negative for SARS-CoV-2 by PCR (group 3). | 2020-06-26 |
| 32505072 | This approach, which can be expressed in terms of picotechnology, makes it possible to identify living cell types or in general, chemical and biological surfaces using their atomic arrays, and applied for early diagnosis even treatment of the disease. | 2020-06-26 |
| 32505076 | We also described Covid-19 treatment outcome, mortality and associated risk factors using univariate and multivariate logistic regression analysis. 17/1878 total diagnosis in our center had lung cancer (0.9 %) versus 1878/320,000 of the total reference population (p = 0.09). 9/17 lung cancer patients with Covid-19 diagnosis died (52.3 %) versus 192/1878 Covid-19 patients in our center (p < 0.0001). | 2020-06-26 |
| 32505172 | Despite widespread use, the accuracy of the diagnostic test for SARS-CoV-2 infection is poorly understood. […] We examined time-series data of laboratory tests for SARS-CoV-2 viral infection, the causal agent for COVID-19, to try to explore, using a Bayesian approach, the sensitivity and specificity of the diagnostic test. […] The best way to better understand bias in the epidemic curves of COVID-19 due to errors in testing is to empirically evaluate misclassification of diagnosis in clinical settings and apply this knowledge to adjustment of epidemic curves. | 2020-06-22 |
| 32505462 | On February 1, 2020, two children(case 1 and case 2), an 8-year-old girl and a 9-year-old boy, were admitted to the isolation ward in Xiangyang Central Hospital, Hubei province, China, with the diagnosis of COVID-19. | 2020-06-17 |
| 32505692 | Different in-house real-time RT-PCR (rRT-PCR) methods for SARS-CoV-2 diagnosis and the appearance of genomes with mutations in primer regions have been reported. […] Hence, whole-genome data from locally-circulating SARS-CoV-2 strains contribute to the knowledge of its global variability and the development and fine tuning of diagnostic protocols. […] To describe the genetic variability of Colombian SARS-CoV-2 genomes in hybridization regions of oligonucleotides of the main in-house methods for SARS-CoV-2 detection, RNA samples with confirmed SARS-CoV-2 molecular diagnosis were processed through next-generation sequencing. […] Genetic variability was detected in Colombian SARS-CoV-2 sequences in some of the primer/probe regions for in-house rRT-PCR diagnostic tests available at WHO COVID-19 technical guidelines; its impact on the performance and rates of false-negative results should be experimentally evaluated. […] The genomic surveillance of SARS-CoV-2 is highly recommended for the early identification of mutations in critical regions and to issue recommendations on specific diagnostic tests to ensure the coverage of locally-circulating genetic variants. | 2020-06-27 |
| 32505777 | Serological SARS-CoV-2 assays are urgently needed for diagnosis, contact tracing and for epidemiological studies. | 2020-06-26 |
| 32506111 | Given its robust capacity for human-to-human transmission and potential of being a nosocomial source of infection, the disease has specific implications on healthcare systems and health care professionals faced with performing essential cardiac procedures in patients with a suspected or confirmed diagnosis of COVID-19. | 2020-06-09 |
| 32506142 | Among the 1397 chest CT scans performed during the pandemic period from 1 March 2020 to 10 May 2020, in two centres with orthopaedic surgery, we selected all the 118 thoracic or chest CT performed for patients who presented to the Emergency Department of the hospital with a diagnosis of trauma for orthopaedic surgical treatment. […] Thirty-nine of these 118 patients were tested with PCR for the diagnosis of COVID-19 infection. | 2020-06-11 |
| 32506145 | A range of prevention strategies, diagnostic work-up, and therapeutic approaches are reported and framed within the COVID-19 pandemic context. | 2020-06-11 |
| 32506258 | A comprehensive document with 46 statements are presented, including protection of medical personnel, etiological treatment, diagnosis and treatment of tissue and organ functional impairment, psychological interventions, immunity therapy, nutritional support, and transportation of critically ill COVID-19 patients. | 2020-06-11 |
| 32506364 | We report a 66-year-old female patient with post-mortem diagnosis of COVID-19 who presented progressive livedo racemosa, acute renal failure and myocardial injury, as well as an absence of respiratory symptoms. | 2020-06-11 |
| 32506726 | Increasingly, confirmed patients being discharged according to the current diagnosis and treatment protocols, follow-up of convalescent patients is important to knowing about the outcome. | 2020-06-19 |
| 32506768 | Diagnosis was confirmed by COVID-19 nucleic acid test by sampling sputum or nasopharyngeal swab. | 2020-06-23 |
| 32506865 | The TCM protocol in the Diagnosis and Treatment Protocol for corona virus disease 2019 (COVID-19) (Trial Version 7) has been updated from previous versions. | 2020-06-22 |
| 32507119 | Semi-structured interviews were conducted with 30 individuals attending the Galway-Roscommon Mental Health Services with an ICD-10 diagnosis of an anxiety disorder to determine the impact of the Covid-19 restrictions on anxiety and mood symptoms, social and occupational functioning and quality of life. | 2020-06-08 |
| 32507123 | This evidence can be helpful in the clinical diagnosis of COVID-19, particularly settings of limited testing capacity. | 2020-06-25 |
| 32507556 | The results reviewed here highlight the importance of considering and further investigating the impact of the current pandemic on the diagnosis and treatment of panic disorder (alone or comorbid with the COVID-19). | 2020-06-11 |
| 32508026 | A colloidal gold immunochromatography assay for IgM/IgG antibodies against the receptor-binding domain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) S1 protein was established to assess its rapid diagnostic value. | 2020-06-08 |
| 32508038 | Nine laboratory parameters were identified to be predictive of a diagnosis of COVID-19. […] Routine laboratory examinations may be helpful for the diagnosis of COVID-19. | 2020-06-11 |
| 32508041 | We summarized clinical phenomes of 3795 patients with COVID-19 based on 80 published reports from the onset of outbreak to March 2020 to emphasize the importance and specificity of those phenomes in diagnosis and treatment of infection, and evaluate the impact on medical services. | 2020-06-11 |
| 32509258 | A more comprehensive diagnostic/therapeutic approach to COVID-19 is proposed, including potential adjuvant interventions aimed at improving hemoglobin dysfunction, iron over-deposit and generalized hypoxic state. | 2020-06-09 |
| 32509415 | On presentation she had severe hypertension, pulmonary edema, elevated brain natriuretic peptide, and high-sensitivity troponin-I, suggesting a diagnosis of hypertensive emergency leading to heart failure with a preserved ejection fraction resulting in pulmonary edema and abnormal cardiac screening tests. | 2020-06-09 |
| 32509472 | Finally, we firmly urge that primer sets for diagnosis be carefully designed, since rapidly occurring variants would affect the performance of the reverse transcribed quantitative PCR (RT-qPCR) based viral testing. | 2020-06-09 |
| 32510005 | An ongoing outbreak of pneumonia associated with a novel coronavirus has been reported worldwide and become a global health problem; hence, the diagnosis and differentiation of this virus from other types of coronavirus is essential to control of the disease. | 2020-06-09 |
| 32510102 | The panel endorsed facility-wide testing of staff and residents without dissent when diagnostic RT-PCR was available. | 2020-06-11 |
| 32510106 | Clinical records of each patients admitted to the hospital with a diagnosis of COVID19 infection were retrospectively analyzed. […] Diagnosis of dementia, modalities of onset of the COVID-19 infection, symptoms of presentation at the hospital and outcomes were recorded. […] In a logistic regression model age, and the diagnosis of dementia resulted independently associated with a higher mortality, and patients diagnosed with dementia presented an OR of 1.84 (95% CI: 1.09-3.13, p<0.05). […] The diagnosis of dementia, especially in the most advanced stages, represents an important risk factor for mortality in COVID-19 patients. | 2020-06-11 |
| 32510164 | The aim of the study was to explore a novel risk score to predict diagnosis with COVID-19 among all suspected patients at admission. […] We found nine independent risk factors for diagnosis with COVID-19 at admission to hospital: epidemiological exposure histories (OR:13.32, 95%CI 6.39-27.75), weakness/fatigue (OR:4.51, 95%CI 1.70-11.96), heart rate <100 beat/min (OR:3.80, 95%CI 2.00-7.22), bilateral pneumonia (OR:3.60, 95%CI 1.83-7.10), neutrophil count ≤6.3×109 /L (OR: 6.77, 95%CI 2.52-18.19), eosinophil count ≤0.02×109 /L (OR:3.14, 95%CI 1.58-6.22), glucose ≥6 mmol/L (OR:2.43, 95%CI 1.04-5.66), D-dimer ≥0.5 mg/L (OR:3.49, 95%CI 1.22-9.96), and C-reactive protein <5 mg/L (OR:3.83, 95%CI 1.86-7.92). […] We designed a novel risk score which might have a promising predictive capacity for diagnosis with COVID-19 among suspected patients. | 2020-06-19 |
| 32510168 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays are urgently needed for rapid diagnosis, contact tracing, and for epidemiological studies. | 2020-06-24 |
| 32510340 | Timely detection and diagnosis are urgently needed to guide epidemiological measures, infection control, antiviral treatment, and vaccine research. […] In this review, biomarkers/indicators for diagnosis of coronavirus disease 2019 (COVID-19) or detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the environment are summarized and discussed. […] However, antibody detection methods can be combined with quantitative real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) to significantly improve the sensitivity and specificity of diagnosis, and boost vaccine research. […] Various specimens for diagnosis or detection are compared and analyzed. […] Chest computerized tomography (CT) scan, RT-qPCR, lateral flow immunochromatographic strip (LFICS) for diagnosis of COVID-19 are summarized and compared. […] Specially, potential electrochemical (EC) biosensor, surface enhanced Raman scattering (SERS)-based biosensor, field-effect transistor (FET)-based biosensor, surface plasmon resonance (SPR)-based biosensor and artificial intelligence (AI) assisted diagnosis of COVID-19 are emphasized. | 2020-06-23 |
| 32510576 | Participants were well informed about the symptoms, diagnosis, modes of transmission, and methods of prevention. | 2020-06-26 |
| 32510901 | We will further describe its mechanism of action, diagnosis, symptoms, and potential effects on the male reproductive system. | 2020-06-08 |
| 32511679 | Diagnostic testing has played and will continue to play a major role in the COVID-19 pandemic. […] Here we discuss questions commonly asked by clinicians about COVID-19 diagnostic testing. | 2020-06-26 |
| 32511784 | There is no knowledge about the diagnosis and clinical management of the drug hypersensitivity reactions that can potentially occur during the disease. […] This review brings togetherall the published information about the diagnosis and management of drug hypersensitivity reactions due to current and candidate off-label drugs andhighlights relevant recommendations. […] Furthermore, it gathers all the dermatologic manifestations reported during the disease for guiding the clinicians to establish a better differential diagnosis of drug hypersensitivity reactionsin the course of the disease. | 2020-06-19 |
| 32511951 | We also review the multidisciplinary management of intrahepatic cholangiocarcinoma as a potentially curable and incurable diagnosis in the setting of COVID-19. | 2020-06-11 |
| 32511971 | The characteristics of laboratory findings of coronavirus are of great significance for clinical diagnosis and treatment. | 2020-06-27 |
| 32512006 | To reduce the risk of infection in HCW, we recommend performing the procedure using techniques that minimize aerosolization while wearing enhanced personal protective equipment (PPE). | 2020-06-11 |
| 32512122 | Cardiac biomarkers can be used to aid in diagnosis as well as risk stratification. | 2020-06-11 |
| 32512271 | The present state of diagnostic and therapeutic developmental race for vaccines against the SARS CoV-2 (nCOVID-19) focuses on prevention and control of this global pandemic which also represents a critical challenge to the global health community. […] In this review, we discuss the strategies for the use of chicken egg yolk (IgY) antibodies in the development of rapid diagnosis and immunotherapy against SARS CoV-2. | 2020-06-23 |
| 32512376 | RT-LAMP could be a simple and easy-to-use diagnostic tool for the detection of SARS-CoV-2. | 2020-06-26 |
| 32512664 | Regarding symptoms at the time of diagnosis, cough (n=38, 35.2%) and fever (n=34, 31.5%) were most common; 12 cases (11.1%) were asymptomatic. | 2020-06-09 |
| 32512742 | Arrays of measures in South Korea, such as large-scale diagnostic testing and technology-based comprehensive contact tracing, have brought about debates among public health experts and medical professionals. | 2020-06-12 |
| 32513289 | Positive IgG against SARS-CoV-2 by rapid diagnostic test. | 2020-06-11 |
| 32513393 | In the absence of adequate diagnosis and treatment of SCC and melanoma in the current lockdown situation in Spain, we can expect to see to a considerable increase in large and thick SCCs and melanomas. | 2020-06-12 |
| 32513452 | The novel coronavirus SARS-CoV-2 (COVID-19) pandemic has created diagnostic uncertainty with regards to distinguishing this infection from pulmonary embolism (PE). | 2020-06-12 |
| 32513515 | In clinical practice, comprehensive care for COPD patients includes the diagnosis using spirometry, clinical examination and comprehensive pharmacological and non-pharmacological management. […] The diagnosis is based on symptoms, dyspnea and lung function impairment and can be mild to very severe. | 2020-06-12 |
| 32513617 | Laboratory-based diagnostic measures including virological and serological tests are essential for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Serological diagnosis of coronavirus disease 2019 (COVID-19) is simple and does not require complex techniques and equipment, rendering it suitable for rapid detection and massive screening. […] Balancing the increased use of laboratory tests, risk of testing errors, need for tests, burden on healthcare systems, benefits of early diagnosis, and risk of unnecessary exposure is a significant and persistent challenge in diagnosing COVID-19. | 2020-06-11 |
| 32513858 | Molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the gold standard for diagnosis of coronavirus disease 2019 (COVID-19), but the clinical performance of these tests is still poorly understood, particularly with regard to disease course, patient-specific factors, and viral shedding. | 2020-06-09 |
| 32513859 | Here, we evaluated four high throughput serologic tests for detection of anti-SARS-CoV-2 IgG antibodies, including assays from Abbott Laboratories (Abbott Park, IL), Epitope Diagnostics Inc. […] With the unprecedented influx of commercially available serologic tests for detection of antibodies against SARS-CoV-2, it remains imperative that laboratories thoroughly evaluate such assays for accuracy prior to implementation. | 2020-06-09 |
| 32513951 | Here, we update the recent understanding in clinical characteristics, diagnosis strategies, as well as clinical management of COVID-19 in China as compared to Italy, with the purpose to integrate the China experience with the global efforts to outline references for prevention, basic research, treatment as well as final control of the disease. | 2020-06-26 |
| 32514228 | So, there is a rapid need for disease diagnosis, vaccine development, and drug discovery to detect, prevent, and treat this sudden and lethal virus. […] Real-time polymerase chain reaction (RT-PCR) is considered as a rapid, accurate, and specific tool for disease diagnosis. | 2020-06-11 |
| 32514616 | Firstly because of the differential diagnosis of cutaneous rash (e.g., drug-related rash or paraviral exanthema). | 2020-06-12 |
| 32514674 | Therefore, the challenge in everyday life will be to achieve in due time the differential diagnosis as well as the long-term psychological impact.Key Points• SSc patients should be encouraged to continue their chronic therapy; in case of immunosuppressive therapy it must be discontinued for safety in case of COVID-19 infection. | 2020-06-24 |
| 32515033 | Immunosuppression can expose cancer patients to serious complications which can lead to delay in diagnosis and unnecessary hospitalizations that may adversely affect the prognosis of the disease. | 2020-06-19 |
| 32515085 | They had minimal symptoms at diagnosis and did not develop any respiratory complications or allograft dysfunction. | 2020-06-28 |
| 32515374 | Polymerase chain reaction (PCR) is the diagnostic test of choice in this pandemic situation. | 2020-06-18 |
| 32515375 | COVID-19 poses a great challenge to clinical and diagnostic services around the world. […] Risk assessment must be carried out before meeting up the diagnostic challenge for COVID-19 and essential biorisk management measures are required to be taken. | 2020-06-18 |
| 32515377 | Hence, cardiorespiratory assessment is an important component of diagnosis, management and follow-up of this disease. | 2020-06-18 |
| 32515382 | Cardiac dysfunction has been identified as a risk factor, a prognostic factor, a diagnostic tool, differential diagnosis, a complication of COVID 19, and a side effect of its treatment. | 2020-06-18 |
| 32515387 | This document is a brief commentary of the imaging modalities used in the screening, diagnosis and management of COVID-19 pneumonia. | 2020-06-18 |
| 32515389 | Standardised guidelines from initial studies are now available for diagnosis, treatment, and prevention. […] Research should now focus on early diagnosis, better drugs for children, intensive care modalities, and a universal vaccine. | 2020-06-18 |
| 32515570 | In patients with COVID-19 who are suspected of VTE or in whom the diagnosis is confirmed, parenteral therapy with low-molecular-weight heparin should be initiated in the absence of contraindications. | 2020-06-26 |
| 32515685 | In children, nasopharyngeal swabs appear to be a more sensitive specimen type for the diagnosis of COVID-19 compared with oropharyngeal swabs. […] The results of this study provide valuable information for the diagnosis and surveillance of COVID-19 and development of SARS-CoV-2 vaccines for use in children. | 2020-06-12 |
| 32516107 | Early diagnosis of atypical cases of COVID-19 infection is critical in reducing the transmission and controlling the present pandemic. […] In the present report, we described a patient with the chief complaints of dyspnea and dry cough referred to the oncology center at Imam Khomeini Hospital, Tehran with the differential diagnosis of lung cancer who was diagnosed and treated for COVID-19 infection in follow up. […] The patient had been referred to this center with the differential diagnosis of lung cancer due to the massive pleural effusion in initial chest CT scan. | 2020-06-09 |
| 32516273 | Inclusion criteria were pregnant women with a confirmed diagnosis of SARS-CoV-2 infection. | 2020-06-09 |
| 32516279 | Diagnostic Level IV. | 2020-06-10 |
| 32516506 | Multiple therapeutic strategies, including antibody therapies (such as Tocilizumab, Sarilumab, Siltuximab), therapeutic plasma exchange (TPE), and blood purification techniques for direct removal of cytokines, including filtration, dialysis (diffusion), and adsorption are available. | 2020-06-19 |
| 32516704 | It has forced oncologists to rethink the entire diagnostic and therapeutic process, based on the local prevalence and impact of COVID-19. […] In this review we will discuss the impact of COVID-19 on patients affected by cancer, their diagnosis and management, as well as the pathophysiology of COVID-19 induced acute respiratory distress symptoms and currently investigated treatment approaches. | 2020-06-19 |
| 32516739 | Rapid and sensitive diagnostic assays for SARS-CoV-2 detection are required for prompt patient management and infection control. […] A total of 289 clinical specimens from 186 patients with suspected COVID-19 and 8 proficiency testing (PT) samples were used to evaluate the diagnostic performance of the LightMix® E-gene kit against in-house developed COVID-19-RdRp/Hel and COVID-19-N RT-PCR assays. | 2020-06-26 |
| 32516833 | The primary endpoint was the incidence of laboratory-confirmed COVID-19 diagnosis or new symptoms requiring self-isolation or hospitalisation after a tracheal intubation episode. | 2020-06-19 |
| 32516836 | The challenge is to define the next generation of interconnectivity tools that would be necessary to achieve a new operational model that, while ensuring low face-to-face interaction between the main players of the diagnostic pipeline, allows maximum interconnectivity to serve our patients and the immediate teaching and research needs associated with clinical tissue/cellular samples. | 2020-06-19 |
| 32517166 | Delays in diagnosis contribute to a delayed start of antifungal therapy. […] We underline the challenges faced in the management of these cases, the importance of early diagnosis and need for surveillance given the emergence of triazole resistance. | 2020-06-11 |
| 32517463 | The variability of case definitions and diagnostic test criteria may have impact on the number of emergency visits and COVID-19 diagnosed cases in Emergency Department. | 2020-06-10 |
| 32517645 | In addition, the median number of days between symptom onset and diagnostic testing has improved considerably from 7 days in the early phase of the outbreak to 1 day in the latest phase of the epidemic. | 2020-06-11 |
| 32517769 | The results provide a valid diagnostic benchmark for evaluating the evolution of COVID-19 pneumonia. | 2020-06-17 |
| 32517835 | We describe a case of delayed COVID-19 diagnosis due to unrecognized community transmission in Atlanta, Georgia in mid-February 2020. […] This case resulted in transmission of COVID-19 to three of the four healthcare workers present during a diagnostic bronchoscopy procedure where only procedural masks were worn. | 2020-06-10 |
| 32518172 | Anosmia, ageusia, other cranial neuropathies and lymphocytopenia are red flags enhancing early diagnostic suspicion. […] Emerging data indicate that COVID-19 can trigger not only GBS but other autoimmune neurological diseases necessitating vigilance for early diagnosis and therapy initiation. | 2020-06-25 |
| 32518454 | With the coronavirus pandemic getting worse, we are turning to new techniques to deliver a vaccine in record time. | 2020-06-11 |
| 32518636 | The pandemic of coronavirus disease 2019 (COVID-19) presents an unprecedented challenge to rapidly develop new diagnostic, preventive and therapeutic strategies. […] In the COVID-19 pandemic era, it is crucial that the adoption of new diagnostic, preventive and therapeutic strategies is based upon evidence coming from well-designed, adequately powered and carefully conducted clinical trials. | 2020-06-17 |
| 32518743 | A mixed-methods research strategy incorporating both quantitative household questionnaire survey and qualitative focus group discussions (FGDs) techniques were applied. | 2020-06-12 |
| 32518804 | Chest CT has a high sensitivity in patients with COVID-19, and it can improve diagnostic accuracy for COVID-19 suspected patients with fever during the initial screen, whereas its value for nonfever patients remains questionable. | 2020-06-11 |
| 32518987 | Chest CT plays a crucial role in the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. […] • Chest CT is valuable for the early diagnosis of COVID-19, particularly for those patients with a negative RT-PCR. | 2020-06-13 |
| 32519293 | In addition, with the ongoing outbreak of COVID-19 and exponentially increasing incidence throughout the world, this report stresses the need for including NCIP in the differential diagnosis of patients with typical image findings in at-risk populations, as early diagnosis is crucial for appropriate patient management and post-exposure recommendations. | 2020-06-13 |
| 32519294 | Despite the technical limitations of the portable CT unit that was repurposed for the UCC, diagnostic-quality images in an acute care setting were successfully obtained. […] Repurposing of a portable CT scanner for use in COVID-19 patients offers a feasible option to obtain diagnostic quality images while minimizing the risk of exposing other patients and hospital staff to an infected patient. | 2020-06-12 |
| 32519406 | After diagnosis, immunosuppression was continued unchanged. | 2020-06-19 |
| 32519594 | Combined with nine articles from Brearly’s analysis, a total of 19 studies were included in the systematic review.Results: Retained studies included samples from 5 different countries, various ethnic/cultural backgrounds, and diverse diagnostic populations. | 2020-06-10 |
| 32519617 | We retrospectively evaluated demographic characteristics, currently used immunosuppressant treatment, present complaints, treatment and diagnosis of comorbid diseases, and results of COVID-19 tests. | 2020-06-24 |
| 32519760 | The diagnosis of coronavirus disease 2019 (COVID-19) is mainly based on a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) result. | 2020-06-24 |
| 32519786 | The diagnosis of non-cardiogenic pulmonary edema due to pulmonary capillary leak syndrome SARS-CoV-2 virus infection was obtained by a medical committee of 6 physicians. […] The diagnosis of COVID-19 infection is confirmed by reverse transcription polymerase chain reaction (RT-PCR) test. | 2020-06-19 |
| 32519809 | The diagnosis is generally suspected from history of household exposure to COVID-19 case. | 2020-06-19 |
| 32519842 | The COVID-19 outbreak has fueled a global demand for effective diagnosis and treatment as well as mitigation of the spread of infection, all through large-scale approaches such as specific alternative antiviral methods and classical disinfection protocols. | 2020-06-26 |
| 32520160 | The present study aimed to review the epidemiology, clinical manifestation, laboratory diagnosis, treatment, and future perspectives related to COVID-19 infections. | 2020-06-15 |
| 32520340 | While the contributions of diagnostic testing for SARS-CoV-2 have received considerable attention, concerns abound regarding the availability of sufficient testing capacity to meet demand. […] Our clinical laboratory and diagnostic infrastructure are capable of incorporating required volumes for many local, regional, and national public health surveillance studies into their current and projected testing capacity. | 2020-06-26 |
| 32520401 | Lack of awareness of these presentations might lead to misdiagnosis, delayed diagnosis and isolation of suspected patients which increases the risk of transmission of infection between patients and doctors. | 2020-06-19 |
| 32520406 | We developed a predictive model for COVID-19 diagnosis based on lung ultrasound and clinical features. […] The characteristics (95%CI) of the model’s diagnostic threshold, applied to the population from which it was derived, were: sensitivity, 97% (83-100%); specificity, 62% (50-74%); positive predictive value, 54% (41-98%); and negative predictive value, 98% (88-99%). | 2020-06-19 |
| 32520508 | However, early diagnosis may be challenging, especially in cancer patients under treatment with immunotherapy as drug-induced pneumonitis can present similar clinical and radiological features. | 2020-06-19 |
| 32520510 | Real-time polymerase chain reaction testing of nasopharyngeal swabs confirmed the diagnosis. | 2020-06-19 |
| 32520580 | With increasing use of point-of-care and portable diagnostic US services, the risk is substantial. CONCLUSION. Our experience and protocols may help service providers with their own effective response against COVID-19. | 2020-06-10 |
| 32520770 | This review introduces current understanding of SARS-CoV-2 infection and treatment strategies, emphasizing the relevant challenges associated with prevention, diagnosis, and management. | 2020-06-10 |
| 32520846 | The diagnosis of coronavirus disease 2019 (COVID-19) is confirmed by reverse transcription polymerase chain reaction. […] With this need for consistency, we propose language for standardized CXR reporting and severity assessment of persons under investigation for having COVID-19, patients with a confirmed diagnosis of COVID-19, and patients who may have radiographic findings typical or suggestive of COVID-19 when the diagnosis is not suspected clinically. […] In addition, we summarize the currently available literature related to the use of CXR for COVID-19 and discuss the evolving techniques of obtaining CXR in COVID-19-positive patients. | 2020-06-10 |
| 32520888 | The diagnosis was confirmed through RNA-PCR testing. […] RNA-PCR test is still the most reliable diagnostic method, especially for asymptomatic patients. | 2020-06-26 |
| 32521074 | Management of lung transplant recipients can be particularly challenging given high levels of maintenance immunosuppression, high incidence of rejection, constant exposure of the graft to the external environment, and diagnostic uncertainty in patients with respiratory symptoms. | 2020-06-19 |
| 32521580 | It was indicated in the diagnosis and treatment scheme, by the National Health Commission of the People’s Republic of China, that blood purifications such as plasma exchange, plasma adsorption, hemoperfusion, hemofiltration and plasmafiltration could be considered for use in the critical patients with cytokine storm syndrome. | 2020-06-10 |
| 32521643 | COVID-19 diagnosis was defined as either “clinically suspected” or “confirmed”, where a severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) test had been performed and was positive. | 2020-06-11 |
| 32521706 | Clinical samples collected in coronavirus disease 19 (COVID-19), patients are commonly manipulated in biosafety level 2 laboratories for molecular diagnostic purposes. | 2020-06-17 |
| 32521953 | To improve the diagnosis, treatment, and prevention of COVID-19 in the elderly, the Expert Committee of Geriatric Respiratory and Critical Care Medicine, China Society of Geriatrics established the “Expert consensus for the diagnosis, treatment, and prevention of Coronavirus disease 2019 in the elderly” . […] (1) For diagnosis, atypical clinical presentation of COVID-19 in the elderly should be emphasized, which may be complicated by underlying disease. | 2020-06-11 |
| 32522067 | Still, much information is not known, including origin of the disease, complete genomic characterization, mechanism of transmission dynamics, extent of spread, possible genetic predisposition, clinical and biological diagnosis, complete details of disease-induced pathogenicity, and possible therapeutic options. | 2020-06-24 |
| 32522074 | In China, diagnostic tests and laboratory tests of specimens from persons under investigation are usually performed in a biosafety level 2 environment. | 2020-06-22 |
| 32522141 | Although some low-income countries have so far reported few cases, it is possible that this is due to limited diagnostic and public health capacity, and may not be reflective of true disease incidence. | 2020-06-11 |
| 32522207 | The resulting pattern may facilitate the process of structure-guided pharmaceutical and diagnostic research with the prospect to identify potential new biological targets. | 2020-06-23 |
| 32522216 | This research should be beneficial to security experts who wish to investigate the impacts of cybersecurity threats on remote healthcare and researchers who wish to identify new modeling opportunities to apply security risk modeling techniques. | 2020-06-17 |
| 32522282 | • Patient admitted to Danish emergency departments, respiratory medicine departments or internal medicine departments • Age≥ 18 years • Hospitalized ≤48 hours • Positive COVID-19 test / diagnosis during the hospitalization (confirmed). | 2020-06-17 |
| 32522606 | As a result, COVID-19 diagnostic test kits were quickly developed, enabling extensive early detection of potential cases. | 2020-06-11 |
| 32522844 | The dual-process model of clinical reasoning is used to analyse the thought processes used to make a diagnosis of COVID-19, including consideration of the variety of differential diagnoses.While SARS-CoV-2 is likely to remain on the differential diagnostic list for a plethora of presentations for the foreseeable future, clinicians should be cautious of ignoring other potential diagnoses due to availability bias. […] A knowledge of infectious mimics prevents COVID-19 from overshadowing other diagnoses, hence preventing delayed diagnosis or even misdiagnosis and consequent adverse outcomes for patients. | 2020-06-25 |
| 32522874 | Using integrated comparative genomics and machine learning techniques, we identify key genomic features that differentiate SARS-CoV-2 and the viruses behind the two previous deadly coronavirus outbreaks, SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), from less pathogenic coronaviruses. | 2020-06-11 |
| 32523136 | Reperfusion therapy is a measure of care in patients with ST-elevation myocardial infarction (STEMI), which should be performed once we have the diagnosis. | 2020-06-23 |
| 32523137 | The low number of diagnostic tests conducted in our country clearly underestimates the real incidence and impact of the disease. | 2020-06-23 |
| 32523257 | Also, the local sensitivities for each model state concerning the model parameters are computed using three different techniques: non-normalizations, half normalizations, and full normalizations. | 2020-06-12 |
| 32523258 | Access to diagnostic tests, treatment facilities with the need to use clinical and prediction tools to guide management Telemedicine has an evolving role. […] Osteoporosis and fragility fractures in elderly individuals pose a real challenge for an appropriate diagnosis and management, during the COVID-19 pandemic. | 2020-06-12 |
| 32523686 | A questionnaire regarding the living condition of pulmonary hypertension patients during coronavirus disease 2019 was designed by pulmonary hypertension diagnostic experts in Wuhan Asia Heart Hospital. | 2020-06-12 |
| 32523921 | We also discuss complications associated with delayed diagnosis in patients who potentially may need mechanical ventilation. | 2020-06-12 |
| 32523923 | We hope our data provide additional insight into the diagnosis and therapeutic options for managing this infection.LEARNING POINTS: Laboratory findings of drained pericardial fluid in a patient with COVID-19 are presented.The clinical presentation of pericardial involvement in COVID-19 infection and the role of echocardiography in diagnosis and management are described. | 2020-06-12 |
| 32523926 | One of them died, while in the other two coronary angiography confirmed the diagnosis but was postponed until after pneumonia resolution because of the risk of virus spread. | 2020-06-12 |
| 32523928 | The diagnosis of pulmonary embolism is challenging in symptomatic COVID-19 patients since shortness of breath, chest pain, tachycardia, tachypnoea, fever, oxygen desaturation and high D-dimer blood levels might be features of both diseases. […] The diagnosis of pulmonary embolism is challenging in COVID-19 patients since symptoms, signs and high D-dimer blood levels might be similar in both diseases.An increase in D-dimer blood levels and a decrease in C-reactive protein blood levels over time may be used as a novel method to predict pulmonary embolism in COVID-19 patients. | 2020-06-12 |
| 32523930 | CRS in patients with coronavirus disease 2019 (COVID-19) is life-threatening and can occur very rapidly after COVID-19 diagnosis. | 2020-06-12 |
| 32523931 | Deep sedation may delay diagnosis. […] Prolonged deep sedation during mechanical ventilation of COVID-19 patients may delay the diagnosis of stroke.The hypercoagulability and a thrombo-inflammatory response in COVID-19 is characterized by an increase in D-dimers and fibrinogen. | 2020-06-12 |
| 32523932 | The diagnosis of embolic stroke (namely, total anterior circulation infarct; TACI) was made. […] During hospitalization, new embolic events occurred and a concomitant diagnosis of COVID-19 was made with progressive respiratory dysfunction followed by multiorgan failure. […] The diagnosis of COVID-19 contributed to the patient’s death. | 2020-06-12 |
| 32523933 | A diagnosis of diaphragmatic rupture and gastric perforation in COVID-19 pneumonia was made. | 2020-06-12 |
| 32524147 | From the 594 patient questions analyzed, confirming diagnosis and seeking medical treatment account for 60.61% and 38.05%, respectively, followed by treating (25.59%), preventing (4.38%), and relieving anxiety (1.68%). | 2020-06-26 |
| 32524164 | The appropriate protective measures for orthopedic surgeons and patients were reviewed (on-site first aid, emergency room, operating room, isolation wards, general ward, etc.) during the entire diagnosis and treatment process of traumatic patients. […] Lessons learnt from our experience provide some recommendations of protective measures during the entire diagnosis and treatment process of traumatic patients and help others to manage orthopedic patients with COVID-19, to reduce the risk of cross-infection between patients and to protect healthcare workers during work. | 2020-06-13 |
| 32524227 | All HCW with exposure to the patient from day of admission until confirmed diagnosis of COVID-19 were identified and underwent oropharyngeal swab testing for SARS-CoV-2 by real-time RT-PCR. | 2020-06-13 |
| 32524445 | Since by now, all diagnostic tests show failure rates such as to raise concerns, the probability of incorporating X-rays into the diagnosis of the disease could be assessed by the medical community, based on the findings, while more research to evaluate the X-ray approach from different aspects may be conducted. | 2020-06-17 |
| 32524785 | Radiological examinations play a crucial role in the early diagnosis and follow-up of COVID-19. | 2020-06-19 |
| 32524962 | These atypical and rare presentations may lead to difficulties in establishing the diagnosis in a timely manner; furthermore, they may lead to unnecessary investigations, extended hospital stays, adverse outcomes, and more strain on healthcare resources. | 2020-06-11 |
| 32525251 | The patient was investigated for another differential diagnosis of Urticaria such as parasitic and bacterial infection, for which negative results were found. | 2020-06-23 |
| 32525548 | Participants included patients who received a diagnosis of COVID-19 according to the criteria issued by the Chinese Health Bureau and were admitted to the hospital. | 2020-06-17 |
| 32525568 | However, there is some cause for optimism, for example, in West Africa where infrastructure like diagnostic testing facilities, intensive care units, surveillance, and systems for reporting emergencies used during the EVD outbreak of 2013-2016 can be leveraged to fight the COVID-19 pandemic. | 2020-06-24 |
| 32526252 | At diagnosis, 64% of patients presented fever, 42% shortness of breath/polypnea, 22% encephalopathy, 96% needed hospitalization or prolonged an ongoing one. […] Serum albumin significantly decreased, while bilirubin, creatinine and prothrombin time significantly increased at COVID-19 diagnosis compared to last available data. […] Seventeen patients died after a median of 10 (4-13) days from COVID-19 diagnosis, with a 30-day-mortality rate of 34%. | 2020-06-13 |
| 32526759 | The aim of this study was to investigate the frequency of olfactory loss in an outpatient population who presented to a coronavirus testing center during a 2-week period and to evaluate the diagnostic value of the symptom “sudden smell loss” for screening procedures. […] In this cross-sectional controlled cohort study, 500 patients who presented with symptoms of a common cold to a corona testing center and fulfilled corona testing criteria completed a standardized diagnostic questionnaire which included the patients’ main symptoms, time course, and an additional self-assessment of the patients’ current smell, taste function, and nasal breathing compared to the level before the onset of symptoms. | 2020-06-11 |
| 32527073 | The diagnosis of cerebrovascular events was confirmed with computed tomography of the brain in most studies reporting neurological events. | 2020-06-22 |
| 32527327 | This case highlights our patient’s clinical course, including diagnostic work-up, medical management, and challenges in defining non-infectivity in a relatively unknown disease. | 2020-06-23 |
| 32527340 | Considering that doctors dominated in the diagnosis and treatment of COVID-19, the results of the questionnaires of doctors were mainly analyzed. | 2020-06-16 |
| 32527342 | According to the diagnostic criteria of Kidney Disease: Improving Global Outcomes (KDIGO), patients with AKI were included in AKI group and those without AKI were included in non-AKI group. | 2020-06-16 |
| 32527343 | To investigate the clinical characteristics of gastrointestinal symptoms in patients with coronavirus disease 2019 (COVID-19) during the whole disease process, and provide reference for etiological diagnosis and treatment. | 2020-06-16 |
| 32527345 | To analyze the epidemiological characteristics and clinical features of the patients with coronavirus disease 2019 (COVID-19), so as to provide basis for clinical diagnosis. […] Epidemic history of contact, fever, pneumonia signs of chest CT, normal or decreased count of leukocyte and lymphopenia are the clinical basis for diagnosis of COVID-19. | 2020-06-16 |
| 32527471 | Furthermore, pleural and lung ultrasound can be an alternative diagnostic test to assess the degree of involvement of the lung parenchyma by means of the evaluation of specific ultrasound patterns, identification of pleural effusions and barotrauma. | 2020-06-14 |
| 32527802 | There is an urgent need for SARS-CoV-2 serologic tests to identify all infected individuals, irrespective of clinical symptoms, to conduct surveillance and implement strategies to contain spread. […] Our results, which reveal the early kinetics of SARS-CoV-2 antibody responses, support using the RBD antigen in serological diagnostic assays and RBD-specific antibody levels as a correlate of SARS-CoV-2 neutralizing antibodies in people. | 2020-06-26 |
| 32528206 | This joint research project evaluated a rapid antigen test for the diagnosis of acute bacterial meningitis which later proved to be adaptable to the field situation during the 1988 MC epidemic. | 2020-06-13 |
| 32528785 | This lack of knowledge leads to diagnostic, therapeutic, and management challenges in such patients. | 2020-06-13 |
| 32529516 | After neurological examination, including a panel of blood cerebrospinal fluid biomarkers, a diagnosis of Miller Fisher syndrome (MFS) was hypothesized and intravenous immunoglobulin therapy (IVIG) was initiated. | 2020-06-15 |
| 32529643 | Forty studies of COVID-19 pregnancies reviewed suggest a lack of consensus on diagnostic strategy for congenital infection. | 2020-06-23 |
| 32529889 | Prevention and control of the pandemic and ensuring the progress of the cancer diagnosis and treatment is a significant problem in the current scenario. […] This article proposes a scientific management system for patients with solid tumors to guarantee emergency surgery, rationally arrange limited-term surgery, appropriately defer elective surgery, and guarantee regular chemotherapy, while protecting children from SARS-CoV-2 infection and ensuring the continuity of comprehensive diagnosis and treatment. | 2020-06-12 |
| 32529906 | In response to the coronavirus disease 2019 (COVID-19) outbreak, caused by the SARS-CoV-2 virus, multiple diagnostic tests are required globally for acute disease diagnosis, contact tracing, monitoring of asymptomatic infection rates and assessing herd immunity. […] While PCR remains the frontline test of choice in the acute diagnostic setting, serological tests are urgently needed to fulfil the other requirements. | 2020-06-12 |
| 32530160 | Objective To retrospectively analyze the forensic pathological postmortem examination and clinical data of children who died of viral pneumonia in identification of cause of death cases and to discuss the clinical characteristics and pathological features of viral pneumonia in children, in order to provide reference to pathological diagnosis of viral pneumonia in children caused by 2019 novel coronavirus （2019-nCoV） infection. […] Analyzing the forensic autopsies and the histopathological characteristics could provide reference for pathological diagnosis of viral pneumonia. | 2020-06-16 |
| 32530284 | Tremendous effort has been given to the development of diagnostic tests, preventive vaccines, and therapeutic medicines for coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] In particular, we have identified mutations on 40% of nucleotides in the nucleocapsid gene in the population level, signaling potential impacts on the ongoing development of COVID-19 diagnosis, vaccines, and antibody and small-molecular drugs. | 2020-06-28 |
| 32530314 | We evaluated the feasibility of multidisciplinary assessment of patients with ALS, using telememedicine during the emergency determined by the COVID-19 pandemic. Methods: All patients included in this survey had received a diagnosis of ALS according to international criteria after a complete clinical and paraclinical assessment during 2019. | 2020-06-12 |
| 32530453 | Diagnosis of COVID-19 was based on positivity of at least 1 of these investigations. | 2020-06-12 |
| 32530494 | The cohort includes 297 patients with confirmed and 105 with clinical diagnosis. […] The latter group consists of cases with inconclusive nucleic acid test but meeting the criteria for clinical diagnosis. | 2020-06-23 |
| 32530503 | We aim to evaluate the change in the diagnostic spectrum in dermatology outpatient applications compared to before COVID-19. […] Repeated applications with the same diagnosis in ten days after the first presentation were ignored. […] We think that many factors, such as affecting the quality of life, risk perception, increased stress burden may cause a change in the diagnostic distribution of the dermatology applications. | 2020-06-19 |
| 32530587 | Our projections showed that if we continued to comply with measures and no drastic changes are seen in diagnosis or management protocols, the epidemic curve would tend to decrease in this time interval. | 2020-06-12 |
| 32530929 | Novel Corona virus/Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 or 2019-nCoV), and the subsequent disease caused by the virus (coronavirus disease 2019 or COVID-19), is an emerging global health concern that requires a rapid diagnostic test. […] The objective of this study was to develop a rapid screening diagnostic test that could be completed in 30-45 minutes. | 2020-06-22 |
| 32531110 | Based on diagnostic and treatment standards developed by EAACI, on international information regarding COVID-19, on guidelines of the World Health Organization (WHO) and other international organizations as well as on previous experience, a panel of experts including clinicians, psychologists, IT experts and basic scientists along with EAACI and the “Allergic Rhinitis and its Impact on Asthma (ARIA)” inititiative have developed recommendations for the optimal management of allergy clinics during the current COVID-19 pandemic. | 2020-06-12 |
| 32531372 | Over 300 million people carry a diagnosis of asthma with data to suggest they are at higher risk for infection or adverse outcomes from SARS-CoV-2. | 2020-06-14 |
| 32531475 | This study aimed to evaluate the diagnostic performance of the Abbott Architect SARS-CoV-2 IgG assay in COVID-19 patients. | 2020-06-26 |
| 32531713 | Receiver operating characteristic (ROC) curve analysis and area under the curve (AUC) were used to assess the diagnostic accuracy. | 2020-06-26 |
| 32532460 | These challenges have particularly distressing for women with a gynecologic cancer diagnosis and their providers. | 2020-06-16 |
| 32532596 | The aim is to review current literature related to the diagnosis, management, and follow-up of suspected and confirmed Covid-19 cases. […] Medical Imaging plays an important auxiliary role in the diagnosis of Covid-19 patients, mainly those most seriously affected. […] Radiography practice has to significantly adjust to these new requirements to support optimal and safe imaging practices for the diagnosis of Covid-19. | 2020-06-25 |
| 32532619 | Many of these cases feature a toxic shock-like syndrome or Kawasaki-like syndrome in the setting of SARS-CoV-2 positive diagnostic testing and the CDC has termed this presentation Multisystem Inflammatory Syndrome (MIS-C). | 2020-06-16 |
| 32532623 | The rapid spread of the virus and the precipitously increasing numbers of cases necessitate the urgent development of accurate diagnostic methods, effective treatments, and vaccines. […] Here, we review the progress of developing diagnostic methods, therapies, and vaccines for SARS-CoV-2 with a focus on current clinical trials and their challenges. […] For diagnosis, nucleic acid amplification tests remain the mainstay diagnostics for laboratory confirmation of SARS-CoV-2 infection, while serological antibody tests are used to aid contact tracing, epidemiological, and vaccine evaluation studies. […] Viral isolation is not recommended for routine diagnostic procedures due to safety concerns. | 2020-06-22 |
| 32532753 | COVID-19 cases in some but not all diagnostic groups had older ages than cases in the reference population. | 2020-06-27 |
| 32532933 | To date, despite the whole world effort to review various aspects of SARS-CoV-2, including epidemiology, clinical manifestations, diagnosis, and treatment options, there are still gaps in the knowledge of this disease and many issues remain unclear. | 2020-06-22 |
| 32532934 | Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. […] Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. […] In this paper, we have reviewed the current array of diagnostics for SARS-CoV-2, highlighted the gaps in current diagnostic modalities, and their role in community surveillance and control of the pandemic. […] The different modalities of COVID-19 diagnosis discussed are: clinical and radiological, molecular based (laboratory based and point-of-care), Immunoassay based (ELISA, rapid antigen and antibody detection tests) and digital diagnostics (artificial intelligence based algorithms). | 2020-06-22 |
| 32532940 | To accommodate limited supplies, techniques for extended use, reuse, and sterilization of masks are strategized. | 2020-06-22 |
| 32532942 | We performed a systematic literature review with meta-analysis, using three databases to assess MERS-CoV and SARS-CoV infection in animals and its diagnosis by serological and molecular tests. | 2020-06-22 |
| 32532943 | In not-confirmed group, Influenza represented the most frequent alternative diagnosis. | 2020-06-22 |
| 32533062 | Here, recent studies are summarized and reviewed, with a focus on virus-host interactions, vaccine-based and drug-targeted therapies, and the development of new approaches for clinical diagnosis and treatment. | 2020-06-28 |
| 32533621 | The diagnostic and containment efforts for the disease have presented significant challenges for the global health-care community. | 2020-06-13 |
| 32533899 | We therefore reached a diagnosis of primary chilblains. | 2020-06-13 |
| 32533986 | Moreover, we aimed to evaluate the diagnostic accuracy of leukocytosis and an elevation of CRP. […] We calculated the diagnostic accuracy of leukocytosis and CRP. | 2020-06-27 |
| 32534013 | Thus, fast and accurate diagnostic methods are of great significance for prevention and accurate treatment. […] In this study, we developed a one-step multiplex TaqMan probe-based real-time PCR for the differential diagnosis of four viruses causing canine diarrhea including, CPV (Canine Parvovirus 2), CCoV (Canine Coronavirus), CAstV (Canine Astrovirus), and CaKoV (Canine Kobuviruses). | 2020-06-16 |
| 32534042 | The median interval between COVID-19 diagnosis to the start of fecal sample collection was 37 days (range, 29-41); 213 stool specimens were collected from 46 patients. […] Shedding of virus into feces persisted until day 50 after diagnosis; fecal samples began to test negative before or at approximately the time that respiratory specimens also began to test negative. | 2020-06-15 |
| 32534175 | A hypothetical three-part prevention, diagnostic, and treatment approach based on an up-to-date scientific literature review for COVID-19 is proposed. […] Regarding diagnosis, a validated screening questionnaire and digital app for COVID-19 could help identify individuals who are at risk of transmitting the disease, as well as those at highest risk for poor clinical outcomes. […] A three-part prevention, diagnostic, and treatment plan is proposed for addressing the severe complications of COVID-19. | 2020-06-16 |
| 32534188 | Diagnosis of SARS-CoV-2 is recommended in respiratory secretions by special molecular tests like PCR, chest scan and common laboratory diagnosis. | 2020-06-16 |
| 32534344 | Overall, the proposed model substantially advances the current radiology based methodology and during COVID-19 pandemic, it can be very helpful tool for clinical practitioners and radiologists to aid them in diagnosis, quantification and follow-up of COVID-19 cases. | 2020-06-26 |
| 32534808 | Considering the first group of six patients, one patient died due to COVID-19 3 days after the diagnosis; while the other patients recovered from COVID-19 after a median of three weeks. | 2020-06-14 |
| 32534909 | The gold standard for diagnosis is nucleic acid detection by real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) in naso-pharyngeal swabs, but, due to limitations in its sensitivity, thoracic imaging plays a crucial, complementary role in diagnostic work-up and it allows also to reveal atypical findings and potential alternative target for sampling, such as pleural effusion. […] Pleural effusion is not a common finding in COVID-19 infection, but a prompt recognition of this potential localization may be useful to optimize diagnostic work-up as well as management of these patients. | 2020-06-28 |
| 32534946 | The knowledge of available laboratory methods is essential for early and correct diagnosis of COVID-19 to identify new cases as well as monitoring treatment of confirmed cases. […] In this review we aim to provide the updated information about selection of specimens and availability of various diagnostic methods and their utility with current findings for the laboratory diagnosis of SARS-CoV-2 infection. […] This will guide the healthcare professionals and government organizations to make strategy for establishing diagnostic facilities for SARS-CoV-2 infections. | 2020-06-14 |
| 32535088 | Ensuring the availability of insulin, other medicines, self-monitoring and diagnostic tools is another challenge. | 2020-06-14 |
| 32535147 | In a retrospective cohort study of patients with COVID-19 from Shamir Medical Centre, Israel, we monitored any use of ibuprofen from a week before diagnosis of COVID-19 throughout the disease. | 2020-06-23 |
| 32535302 | During novel RNA viral outbreaks, detection of the virus relies on real-time reverse transcription polymerase chain reaction (real-time RT-PCR) for detection of the RNA of the virus In the case of SARS-CoV-2, RT-PCR is used for confirmatory diagnosis of symptomatic patients as well as increasingly screening of asymptomatic contacts and subjects at risk. […] The unprecedented outbreak posed the challenge of evaluating the different diagnostic RT-PCR assays sensitivity and specificity without a previous established gold standard.Since the availability of the first SARS-CoV-2 genomic sequence (Wu et al., 2020), several studies have reported a rapid genetic evolution of SARS-CoV-2 through a phylogenetic tree tracking the geographical spread of the virus (Andersen et al., 2020; The Open Science Prize, 2020; Wu et al., 2020; Yi, 2020). […] The impact of non-3 terminal mismatches should not be underestimated, especially in a diagnostic environment (Stadhouders et al., 2010; Whiley and Sloots, 2005). […] CDC 2019-novel coronavirus (2019-nCoV) real-time RT-PCR diagnostic panel. 2020b; Accessed: 09 Apr 2020. […] Molecular diagnosis of a novel coronavirus (2019-nCoV) causing an outbreak of pneumonia. […] Potential preanalytical and analytical vulnerabilities in the laboratory diagnosis of coronavirus disease 2019 (COVID-19). | 2020-06-28 |
| 32535397 | The pandemic’s initial challenges include broad diagnostic testing, consistent reagent supply lines, and access to laboratory instruments and equipment. | 2020-06-26 |
| 32535398 | A diagnostic comparison study was performed by testing nasopharyngeal samples from persons under investigation for coronavirus disease 2019 (COVID-19). | 2020-06-26 |
| 32535725 | CT imaging has been a detrimental tool in the diagnosis of COVID-19, but it has not been studied thoroughly in pediatric patients and its role in diagnosing COVID-19. 27 pediatric patients with COVID-19 pneumonia were included. | 2020-06-17 |
| 32535768 | In this article, we provide a molecular overview on the SARS-CoV-2 virus and summarize tremendous efforts that have been made to develop a rapid confirmatory diagnostic test for COVID-19. […] The diagnostic performances of the available tests are analyzed based on the best current information from the early research. | 2020-06-17 |
| 32535787 | Ultrasound is the most disruptive innovation in intensive care life, above all in this time, with a high diagnostic value when applied appropriately. […] In recent years, point-of-care lung ultrasound has gained significant popularity as a diagnostic tool in the acutely dyspnoeic patients. | 2020-06-17 |
| 32535837 | The most common diagnosis of these visits was postoperative state (20 visits, 9% of the total), followed by conjunctivitis (16 visits, 7%), and keratitis (14 visits, 6%). | 2020-06-17 |
| 32535876 | We are discussing some of the clinical challenges and the pitfalls in molecular diagnosis of SARS-CoV-2, including the fact that a positive PCR result may not always reflect infectiousness. | 2020-06-17 |
| 32535885 | Patients with a diagnosis of interstitial pneumonia caused by SARS-CoV-2, presenting with mild symptoms, and requiring hospitalization in a non-intensive care unit with known discharge status were prospectively collected and retrospectively analyzed. | 2020-06-14 |
| 32535955 | This paper answers pressing questions, formulated by young clinicians and scientists, on SARS-CoV-2, COVID-19 and allergy, focusing on the following topics: virology, immunology, diagnosis, management of patients with allergic disease and asthma, treatment, clinical trials, drug discovery, vaccine development and epidemiology. | 2020-06-14 |
| 32536002 | Any deviation of the diagnostic sensitivity and specificity will reduce the predictive values of the test. […] Here, we report the occurrence of contaminations of commercial primers/probe sets with the SARS-CoV-2 target sequence of the RT-qPCR as an example for pitfalls during PCR diagnostics affecting diagnostic specificity. […] Hence, it appears imperative to pre-test each batch of reagents extensively before use in routine diagnosis, to avoid false-positive results and low positive predictive value in low-prevalence situations. […] As such, contaminations may have happened more widely, COVID-19 diagnostic results should be re-assessed retrospectively to validate the epidemiological basis for control measures. | 2020-06-14 |
| 32536226 | Therefore, further studies, particularly in the context of the virus pathogenesis, diagnosis, treatment, and vaccine development, are warranted. | 2020-06-15 |
| 32537561 | Several rapid diagnostic tests have been developed at an astonishing pace; however, COVID-19 requires more highly specific rapid point-of-care diagnostic tests. […] This review describes the currently available testing approaches, as well as the available test assays including the Xpert® Xpress SARS-CoV-2 test (takes ~45 min) and Abbott ID COVID-19 test (5 min) as easy to use point-of-care tests for diagnosis of novel COVID-19 that have so far received the US Food and Drug Administration emergency use authorizations clearance. […] This review is correct as of the date published and will be updated as more diagnostic tests come to light. | 2020-06-15 |
| 32537687 | Since papillary carcinoma was the preoperative diagnosis in all cases, radioactive iodine ablation (RIA) therapy was also planned 3-4 weeks following surgery after withdrawing thyroxine and achieving a thyroid stimulating hormone (TSH) level > 30 mU/L. | 2020-06-19 |
| 32537957 | CRP > 8.0 mg/dL was strongly associated with MV/HFNC (odds ratio, 26.31; 95% confidence interval, 7.78-88.92; P < 0.001), and showed better diagnostic characteristics compared to commonly used clinical scores. | 2020-06-18 |
| 32538594 | Diagnostic criteria include onset within one week of a known insult or new or worsening respiratory symptoms, profound hypoxemia, bilateral pulmonary opacities on radiography, and inability to explain respiratory failure by cardiac failure or fluid overload. | 2020-06-16 |
| 32538664 | Through the use of online platforms such as websites, mobile applications, and social media, survivors and perpetrators alike can access tools that help them manage stressors induced by the coronavirus as well as practice emotional regulation techniques and communication strategies at home. | 2020-06-15 |
| 32538806 | According to this classification, the working panel agreed on the distribution of the different diagnostic, therapeutic and follow-up scenarios for PC. […] The risk of severe morbidity as a result of SARS-CoV-2 infection may out weigh the risk of PC morbidity/mortalityin many men; therefore, in the short term it is unlikely that delays in diagnosis or treatment can led to worse cancer outcomes. | 2020-06-18 |
| 32538809 | To provide a priority algorithm for determinate diagnostic, therapeutic and follow-up procedures regarding at testicular cancer, adjusted by institutional requirements. […] The authors support prioritizing diagnostic and therapeutic procedures. […] Initial diagnostic procedures for testicular cancer such as scrotal US, orchiectomy, staging CT and adjuvant treatment (if required) are priority. | 2020-06-18 |
| 32538810 | Clear diagnostic and treatment criteria and referral criteria must be established. […] The diagnosis and prescription of treatment for BPH during the COVID-19 pandemic should be based on telemedicine and joint protocols for primary care attention and urology. | 2020-06-18 |
| 32538811 | Most diagnostic and therapeutic procedures in Andrology can be safey postponed during the COVID-19 pandemic. | 2020-06-18 |
| 32538812 | Offer some recommendations or guidelines during the evolution of the COVID-19 pandemic in terms of diagnosis, treatment and follow-upin the field of Reconstructive Urology. […] In addition, consensus was reached on recommendations regarding the diagnosis and follow-up of pathology in the field of Reconstructive Urology. […] CONCLUSIONS: Tools should be implemented to facilitate the gathering of the medical visit and diagnostic tests. | 2020-06-18 |
| 32538813 | MATERIAL AND METHODS: Experts in Functional Urology from different autonomous communities of Spain were contacted to design a strategy to reorganize the activity of both, diagnosis and treatment. | 2020-06-18 |
| 32538814 | MATERIALS AND METHODS: Non-systematic review of the literature and national experts’ opinion summarizing the recommendations in the diagnosis, management, and follow-up of neurourological patients during the COVID-19 pandemic. | 2020-06-18 |
| 32538820 | The Goddess of Health had two daughters, Panacea and Higinia, the fruit of the first is diagnosis, prognosis and treatment, and the fruit of the second is health management, prevention, and statistics. | 2020-06-18 |
| 32538893 | Chest CT is highly recommended as the preferred imaging diagnosis method for COVID-19 due to its high density and high spatial resolution. | 2020-06-23 |
| 32538935 | The national public health emergency management mechanisms need further strengthening with the proactive engagement of relevant ministries; we need a strong, real-time national surveillance system and capacity building of a critical mass of health care workers; there is a need to further assess infection prevention and control capacity; expand the network of virus diagnostic laboratories in the private sector with adequate surge capacity;implement participatory community engagement interventions and plan for a phased lockdown exit strategy enabling sustainable suppression of transmission at low-level and enabling in resuming some parts of economic and social life. | 2020-06-24 |
| 32539257 | Because of its dynamic, real-time, non-invasive, repeatable and other advantages, critical ultrasonography can be widely used in the diagnosis, assessment and guidance of treatment for severe patients. | 2020-06-16 |
| 32539267 | Given limited capacities in most health care systems, diagnostic testing is mainly performed in symptomatic patients or those with relevant exposure. […] We report an intraoperative diagnosis of COVID-19 in an asymptomatic patient, prompted by clinical signs. | 2020-06-18 |
| 32539299 | Real-time reverse transcription (RT)-PCR to detect SARS-CoV-2 RNA is currently the most reliable diagnostic method for confirming COVID-19 worldwide. […] Guidelines for clinical laboratories on the COVID-19 diagnosis have been recently published by Korean Society for Laboratory Medicine and the Korea Centers for Disease Control and Prevention. […] Therefore, this guideline is intended as a practical and technical supplement to the “Guidelines for Laboratory Diagnosis of COVID-19 in Korea”. | 2020-06-24 |
| 32539587 | Early diagnosis is an essential key to limit the outbreak of the virus. | 2020-06-19 |
| 32539692 | Patients in group 1 (n = 51) presented with symptoms of COVID-19 according to the diagnostic criteria. | 2020-06-22 |
| 32539942 | Eligibility criteria were the presence of any thoracic cancer (non-small-cell lung cancer [NSCLC], small-cell lung cancer, mesothelioma, thymic epithelial tumours, and other pulmonary neuroendocrine neoplasms) and a COVID-19 diagnosis, either laboratory confirmed with RT-PCR, suspected with symptoms and contacts, or radiologically suspected cases with lung imaging features consistent with COVID-19 pneumonia and symptoms. […] Data on demographics, oncological history and comorbidities, COVID-19 diagnosis, and course of illness and clinical outcomes were collected. […] Between March 26 and April 12, 2020, 200 patients with COVID-19 and thoracic cancers from eight countries were identified and included in the TERAVOLT registry; median age was 68·0 years (61·8-75·0) and the majority had an Eastern Cooperative Oncology Group performance status of 0-1 (142 [72%] of 196 patients), were current or former smokers (159 [81%] of 196), had non-small-cell lung cancer (151 [76%] of 200), and were on therapy at the time of COVID-19 diagnosis (147 [74%] of 199), with 112 (57%) of 197 on first-line treatment. 152 (76%) patients were hospitalised and 66 (33%) died. 13 (10%) of 134 patients who met criteria for ICU admission were admitted to ICU; the remaining 121 were hospitalised, but were not admitted to ICU. | 2020-06-19 |
| 32539986 | A combination of RT-PCR and serology should be implemented for case finding and contact tracing to facilitate early diagnosis, prompt isolation, and treatment. | 2020-06-19 |
| 32540054 | It summarizes data concerning COVID-19 transmission, diagnosis, and clinical presentation highlighting the information significant for otolaryngologists. | 2020-06-19 |
| 32540142 | It is hoped that through this article, surgeons will have a better system in hepatobiliary diseases classification, treatment selection, and protective measures to improve the clinical practice in accordance with the guidelines for the diagnosis and treatment of the novel coronavirus pneumonia. | 2020-06-19 |
| 32540264 | Previous studies have paid more attention to the epidemic situation of COVID-19 and patient diagnosis and treatment. | 2020-06-19 |
| 32540267 | To propose, based on expert advice and current evidence where available, a strategy to reorganize female and functional urological (FFU) activity (diagnosis and treatment). | 2020-06-19 |
| 32540370 | Investigation of clinical characteristics and outcomes of severe cases of COVID-19 will contribute to early prediction, accurate diagnosis, and treatment to improve the prognosis of patients with severe illness. | 2020-06-19 |
| 32540791 | Airway examination techniques are procedures that can potentially transmit infectious diseases to both patients and healthcare professionals who perform them, by various mechanisms. […] Being already in the early stages after the peak of the pandemic, we still do not know for sure what its consequences will be in the short or long term, since there are important gaps in the knowledge of aspects as fundamental as the transmission mechanisms of the virus, its pathophysiology and immune response or its diagnosis. […] In this review we will examine the different examination techniques available on the assessment of patients suffering from respiratory allergy, asthma and associated diseases, int the postpandemic momentum, highlighting their possible advantages and disadvantages. […] And at the same time we will approach the analysis of the intrinsic value that these interventions provide from the point of view of both diagnosis and management of these patients. | 2020-06-16 |
| 32540883 | Increasing appreciation of this by clinicians will ensure earlier diagnosis, monitoring and treatment of patients presenting with this. | 2020-06-23 |
| 32541213 | Both open surgical and percutaneous dilational tracheostomy techniques were performed utilizing methods to mitigate aerosols. | 2020-06-16 |
| 32541273 | This article explores the current literature and suggests saliva as an emerging potential diagnostic specimen for COVID-19 testing. | 2020-06-16 |
| 32541542 | Surgeons operating in the head and neck are particularly at risk of occupational COVID-19 exposure during diagnostic and therapeutic procedures and must therefore be cognizant of protocols in place to mitigate exposure risk and optimize patient care. | 2020-06-16 |
| 32541971 | Bedside blood purification treatment in the COVID-19 isolation ward, the occurrence and spread of healthcare associated infection can be effectively controlled through effective infection prevention and control management, including divisional isolation, patient behavior isolation and patient placement, operator personal protection and hand hygiene, dialysis waste fluid disposal, isolation room’s air purification, object surfaces, medical devices and medical fabrics disinfection, which can provide experience for diagnosis, treatment and prevention and control of patients in the respiratory infectious disease ward. | 2020-06-17 |
| 32542102 | The diagnosis of COVID-19 was confirmed afterward by laboratory testing. | 2020-06-17 |
| 32542123 | The first patient presented with symptomatic atrial fibrillation; however, during his hospitalization course, he developed a fever, which led to the diagnosis of infection with SARS-CoV-2. | 2020-06-17 |
| 32542159 | Given the patient’s lack of respiratory symptoms, diagnosis and treatment were ultimately delayed. | 2020-06-17 |
| 32542185 | The current project provides a novel tool for biological studies that can contribute to breakthroughs in coronavirus diagnosis, treatment, and prevention. | 2020-06-17 |
| 32542206 | We describe a Thai patient with an initial diagnosis of dengue fever who was later confirmed to also infect with SARSCoV-2. | 2020-06-17 |
| 32542208 | Meanwhile, detecting specific antibodies in blood, such as the IgM antibody, against the SARS-CoV-2 virus is another choice for COVID-19 diagnosis, as it is widely accepted that IgM is an important indicator in the acute infection period. […] In this study, a colloidal gold nanoparticle-based lateral-flow (AuNP-LF) assay was developed to achieve rapid diagnosis and on-site detection of the IgM antibody against the SARS-CoV-2 virus through the indirect immunochromatography method. […] As a whole, in the light of its advantages such as excellent specificity and stability, easy operation, low cost, and being less time-consuming, AuNP-LF assay is a feasible method for the diagnosis of COVID-19 in primary hospitals and laboratories, especially in emergency situations in which numerous samples need to be tested on time. | 2020-06-17 |
| 32542238 | The aim of our study was to compare the characteristics of loss of smell and taste between patients with a clinical diagnosis of SARS-CoV-2 infection to patients with a RT-PCR diagnosis. | 2020-06-16 |
| 32542571 | Thus, concerns about the reducing and management of COVID-19 are on the rise, as there is need to provide diagnosis, treatment, monitoring, and follow-ups during the pandemic. | 2020-06-23 |
| 32542637 | Psychiatric and psychotherapeutic care needs to be adapted accordingly; the specific burden and distress needs to be examined actively in patients from all diagnostic groups. | 2020-06-16 |
| 32543154 | The chest CT findings of the pneumonia patients with coronavirus disease 19 (COVID-19) were summarized to provide an auxiliary diagnostic basis for the early detection of infected patients. […] As an important diagnostic examination method for COVID-19, CT is conducive to the rapid diagnosis of the disease in patients with epidemiological history. | 2020-06-17 |
| 32543260 | Therefore, regarding the current situation of the COVID-19 pandemic, it is indispensable that the possible diagnosis of COVID-19 vasculopathy is considered in all ischemic strokes of unclear etiology. | 2020-06-25 |
| 32543753 | A reasonable understanding of the performance of reagents with different methodologies can help in clinical disease diagnosis effectively and assist in the diagnosis of the progression of COVID-19, for which the dynamic changes of antibody will provide reliable evidence. | 2020-06-16 |
| 32543802 | Important perioperative management recommendations during this outbreak are emphasized, in addition to discussion of current treatment techniques and strategies available in the battle against COVID-19. | 2020-06-25 |
| 32544042 | The authors provide scientific basis to urologists to help identify patients by remote consultation who are likely to be harmed by coming to the hospital, and not to miss those who need hospitalization for diagnostic or therapeutic interventions. | 2020-06-22 |
| 32544053 | Successful deployment of serologic studies depends on type and performance of serologic tests, population studied, use of adequate study designs, and appropriate analysis and interpretation of data. | 2020-06-16 |
| 32544155 | We describe the clinical and epidemiological characteristics of pediatric patients to provide valuable insight into the early diagnosis and assessment of COVID-19 in children. | 2020-06-25 |
| 32544294 | Immunosuppressive or cytotoxic treatment within 3 months of the diagnosis of SARS-CoV-2 infection was associated with a significantly higher preliminary Case Fatality Rate (pCFR) of 70%, compared with 28% in those not on active treatment (P = 0.0013, 2 proportions z-test). | 2020-06-16 |
| 32544372 | These VH domains may have potential applications for prophylaxis and therapy of COVID-19 alone or in combination, as well as for diagnosis and as tools for research. | 2020-06-26 |
| 32545224 | In this paper, we consider a diagnosis method for COVID-19, which is characterized by a very rapid rate of infection and is widespread. […] A possible method for avoiding severe infections is to stop the spread of the infection in advance by the prompt and accurate diagnosis of COVID-19. | 2020-06-17 |
| 32545409 | This review explores advances in diagnostic criteria, prognostic factors, and management for subsites including head and neck squamous cell carcinoma and the various forms of skin cancer (basal cell carcinoma, cutaneous squamous cell carcinoma, Merkel cell carcinoma, and melanoma). | 2020-06-19 |
| 32545556 | The epidemic that broke out in Chinese Wuhan at the beginning of 2020 presented how important the rapid diagnosis of malnutrition (elevating during intensive care unit stay) and the immediate implementation of caloric and protein-balanced nutrition care are. […] The Chinese have published their recommendations including principles for the diagnosis of nutritional status along with the optimal method for nutrition supply including guidelines when to introduce education approach, oral nutritional supplement, tube feeding, and parenteral nutrition. | 2020-06-24 |
| 32545809 | The centers and institutions that deal with the diagnosis and intervention of children with autism spectrum disorder (ASD) require rapid functional adaptation to respond to patients’ needs. […] The possibility of using technology to activate and manage diagnostic (preliminary diagnosis) and intervention processes should be explored. […] Two developed telemedicine working models for diagnosis and intervention, including synchronous and asynchronous transmissions, are presented. […] The diagnosis step is composed by two different and consecutives phases: (A) pre-specialistic consultation (PSC) and (B) specialistic assessment. | 2020-06-17 |
| 32546018 | Moreover, the present review investigates the epidemiology, diagnosis, structure, and replication of COVID-19 for better understanding. | 2020-06-25 |
| 32546365 | To evaluate the diagnostic utility of additional whole-chest computed tomography (CT) in identifying otherwise unheralded COVID-19 lung disease as part of an acute abdominal pain CT imaging pathway in response to the COVID-19 pandemic. […] Whole-chest CT as part of an acute abdominal pain CT imaging pathway has a very low diagnostic yield for our cohort of patients. | 2020-06-19 |
| 32546368 | Using the Real-time Polymerase Chain Reaction techniques for SARS-CoV-2 nucleic acids, the possible presence of this germ in vaginal discharge and amniotic fluid was investigated in four pregnant Caucasian patients affected by mild acute symptoms of COVID-19 during the second trimester of pregnancy. | 2020-06-19 |
| 32546678 | MATERIAL AND METHODS A retrospective study included 141 patients with a diagnosis of COVID-19. […] The diagnosis was confirmed using real-time reverse transcription-polymerase chain reaction (RT-PCR) for SARS-CoV-2. | 2020-06-23 |
| 32546849 | Various SARS-CoV-2 diagnostic kits are already available from many companies and national health agencies. […] However, publicly available information on these diagnostic kits is lacking. […] During the development of the detection protocol, we found that unoptimized primer sets could inadvertently show false-positive results, raising the possibility that commercially available diagnostic kits might also contain primer sets that produce false-positive results. | 2020-06-19 |
| 32547039 | With the rise of COVID-19 in China and worldwide, further prevention, diagnosis, and treatment measures are a critical unmet need. […] This paper summarizes the influence of COVID-19 on cerebrovascular disease and discusses possible pathophysiological mechanisms to provide new angles for the prevention and diagnosis of this disease. | 2020-06-19 |
| 32547222 | To prevent further spread of the disease, restrictions of population flow from the government and measures to reduce virus transmission from hospitals may lead to the delay of diagnosis and treatment in patients with nasopharyngeal carcinoma (NPC). […] The waiting intervals of each step and variation from the diagnosis and treatment path of NPC between two groups were compared. […] The prevalence of COVID-19 caused delay in the diagnosis and treatment of NPC patients to a certain extent. […] More specific measures should be taken to balance the risk of delayed diagnosis and treatment of NPC and infection of COVID-19. | 2020-06-19 |
| 32547309 | Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased. Conclusion: Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients. | 2020-06-22 |
| 32547908 | Background: To slow the increasing global spread of the SARS-CoV-2 virus, appropriate disinfection techniques are required. | 2020-06-19 |
| 32548163 | What is the clinical diagnosis and how should such patients be treated? […] As a clinician, mastery of the clinical characteristics, basic diagnosis, and treatment methods of COVID-19 are required to provide help to patients. […] We report a typical case of COVID-19, analyze its clinical characteristics, summarize its clinical diagnosis and treatment experience, and provide a reference for clinical colleagues. | 2020-06-19 |
| 32548600 | Nosocomial infection prevention and control concepts and measures relating to dental diagnosis and treatment are critically checked in the hospital. | 2020-06-18 |
| 32548613 | Among 174 positive employees reached for follow-up at least 14 days after diagnosis, 6 reported COVID-related hospitalization; all recovered. | 2020-06-17 |
| 32548635 | Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. | 2020-06-17 |
| 32549025 | The diagnosis of COVID-19 is made by detection of SARS-CoV-2 RNA by reverse transcription polymerase chain reaction (RT-PCR). | 2020-06-25 |
| 32549074 | We aim to summarise updates on diagnosis, treatment and follow up of bladder cancer during the COVID-19 outbreaks. | 2020-06-17 |
| 32549076 | Known laparoscopic and robotic assisted approaches and techniques for the surgical management of urological malignant and benign diseases are commonly used around the World. […] A concern with the use of minimally invasive techniques arose due to a proposed risk of viral transmission of the coronavirus disease with the creation of pneumoperitoneum. | 2020-06-17 |
| 32549077 | A non-systematic review of available literature on the management of urological malignancies during the COVID-19 pandemic was performed to summarize recommendations to improve the diagnosis and treatment of urological cancers during and after the contingence, including clinical and research aspects. […] Urological cancer diagnosis and management should be tailored according to the severity of the COVID-19 crisis in each region and the aggressiveness of each tumor. | 2020-06-17 |
| 32549297 | Finally, we have highlighted some diagnostic challenges in the recognition of SARS-CoV-2 infection in cancer-infected patients. | 2020-06-18 |
| 32550054 | Given the scarcity of resources including healthcare staff, hospital capacities, test kits, etc., timely diagnosis and treatment of this virus are of paramount importance. […] Because the spreading rate of the virus is very high worldwide and there is no definitive treatment, diagnosis becomes even more important. […] The objective of this review is to evaluate the use of chest computed tomography, one of the commonly used radiologic imaging modalities, in the diagnosis of COVID-19 in light with the current literatüre. | 2020-06-19 |
| 32550056 | Real-time polymerase chain reaction (PCR; rt-PCR) is the gold standard diagnostic test, and chest X-ray and computed tomography (CT) scan are the other main investigations. | 2020-06-19 |
| 32550070 | We studied the different pathologies underlying GGO features: neoplastic diseases and non-neoplastic diseases (viral pneumonias, interstitial pneumonias, and cardiopulmonary diseases) in order to avoid pitfalls and to reach the correct diagnosis. […] Conclusions GGO remains a diagnostic challenge. […] Although CT represents a fundamental diagnostic tool because of its sensitivity, it still needs to be integrated with clinical data to achieve the best clinical management. | 2020-06-19 |
| 32550256 | The diagnosis is based on RT-PCR test through a nasopharyngeal swab. […] Here, we review the pertinent clinical findings and the current published data describing chest CT findings in COVID-19 pneumonia, the diagnostic performance of CT for diagnosis, including differential diagnosis, as well the evolving role of imaging in this disease. | 2020-06-19 |
| 32550670 | A consensus regarding urgent laparoscopic procedures, setting and operation techniques was obtained within the Committee and the Board. Conclusions: The ESPES proposes the following recommendations in case minimally invasive surgery is needed in a COVID-19 positive pediatric patients: (1) consider conservative treatment whenever safely possible, (2) dedicate a theater, columns and reusable laparoscopic instrumentation to COVID-19 pediatric patients, (3) prefer disposable instrumentation and cables, (4) use low CO2 insufflation pressures, (5) use low power electrocautery, (6) prefer closed-systems CO2 insufflation and desufflation systems, and (7) avoid leaks through ports. | 2020-06-23 |
| 32550706 | Responsible use of these tools can help quickly disseminate important new information, relevant new scientific findings, share diagnostic, treatment, and follow-up protocols, as well as compare different approaches globally, removing geographic boundaries for the first time in history. | 2020-06-18 |
| 32550954 | It is suggested that stratification by frailty level may help to detect the most vulnerable, and decisions about healthcare resource prioritization should not be taken based only on age itself or previous diagnosis, such as having dementia. | 2020-06-20 |
| 32551102 | It highlights the challenges faced and the appropriate responses to ensure the provision of diagnostic facilities during the COVID-19 outbreak. | 2020-06-20 |
| 32551205 | By the end of February 2020 in Taiwan, 2,150 patients received diagnostic COVID-19 testing and 39 confirmed cases were detected. | 2020-06-20 |
| 32551214 | Early diagnosis and surgical therapy are critical in patients with gangrenous cholecystitis. | 2020-06-20 |
| 32551408 | Surgical procedures must be categorized according to aerosolization risk and the possibility of COVID-19 diagnosis, according to use of personal protective equipment. | 2020-06-20 |
| 32551453 | The main steps for diagnosis of COVID-19 are investigation of symptoms, recollection of travel and physical contact history, and testing using the real time polymerase chain reaction (RT-PCR) test. | 2020-06-20 |
| 32551560 | These aptamers present an opportunity for generating new probes for recognition of SARS-CoV-2, and could provide assistance in the diagnosis and treatment of SARS-CoV-2 while providing a new tool for in-depth study of the mechanisms behind the coronavirus infection. | 2020-06-19 |
| 32551792 | The purpose of this article is to overview the history, epidemiology, clinical characteristics, diagnosis, and treatment of COVID 2019 reported in recently published studies. | 2020-06-23 |
| 32551815 | To conduct a rapid validation study assessing our ability to reliably provide diagnostic Neuropathology services via a whole slide imaging (WSI) platform as part of our departmental COVID-19 planning response. […] This retrospective study assessed diagnostic concordance of neuropathological diagnoses rendered via WSI as compared to those originally established via traditional histopathology in a cohort of 30 cases encompassing a broad range of neurosurgical and neuromuscular entities. […] There were no major or minor diagnostic discrepancies identified in either the attending neuropathologist or neuropathology trainee groups for either the neurosurgical or neuromuscular case cohorts. […] This study provides a framework for rapid subspecialty validation and deployment of WSI for diagnostic purposes during a pandemic event. | 2020-06-19 |
| 32551916 | To evaluate the feasibility, utility, and limitations of a rapid community behavioral diagnosis (RCBD) for social distancing behaviors to prevent coronavirus transmission during a global coronavirus pandemic. | 2020-06-19 |
| 32552415 | Typical presentations of Coronavirus Disease 2019 (COVID19) including respiratory symptoms (cough, respiratory distress and hypoxia), fever and dyspnea are considered main symptoms in adults, but atypical presentation children could be a diagnostic challenge We report three children whose initial presentation was gastrointestinal, and in whom COVID-19 infection was found, concluding that cases of acute appendicitis, mesenteric adenitis and flank tenderness may mask and infection with this virus, which should therefore be investigated. | 2020-06-19 |
| 32552534 | The crystallographic structures of 3CLpro (PDB: 6LU7) and RdRp (PDB 6ML7) were used in virtual screening of 50000 chemical compounds obtained from the CAS Antiviral COVID19 database using 3D-similarity search and standard molecular docking followed by ranking and selection of compounds based on their binding affinity, computational techniques for the sake of details on the binding interactions, absorption, distribution, metabolism, excretion, and toxicity prediction; we report three 4-(morpholin-4-yl)-1,3,5-triazin-2-amine derivatives; two compounds (2001083-68-5 and 2001083-69-6) with optimal binding features to the active site of the main protease and one compound (833463-19-7) with optimal binding features to the active site of the polymerase for further consideration to fight COVID-19. | 2020-06-25 |
| 32552642 | The international health authorities have focused on rapid diagnosis and isolation of patients as well as search for therapies able to counter the disease severity. | 2020-06-19 |
| 32552794 | Clinical diagnosis could be a good complement to the method of confirmation at that time. | 2020-06-28 |
| 32553046 | Rapid diagnostic tests (RDTs) play a critical role in malaria diagnosis and control. | 2020-06-19 |
| 32553061 | We reviewed the diagnostic accuracy of SARS-CoV-2 serological tests. | 2020-06-26 |
| 32553070 | Among 6 contacts who had serologic tests, none were positive. | 2020-06-19 |
| 32553309 | The TB treatment centres and hospitals needs to be prepared for early diagnosis and management of severe COVID-19 in TB patients. | 2020-06-22 |
| 32553350 | This situation highlights the need for rapid, sensitive SARS-CoV-2 diagnostic assays capable of high-throughput operation that can preferably utilize existing equipment to facilitate broad, large-scale screening efforts. […] CRISPR assay diagnostic results obtained nasal swab samples of individuals with suspected COVID-19 cases were comparable to paired results from a CDC-approved quantitative RT-PCR (RT-qPCR) assay performed in a state testing lab, and superior to those produced by same assay in a clinical lab, where the RT-qPCR assay exhibited multiple invalid or inconclusive results. […] Our assay also demonstrated greater analytical sensitivity and more robust diagnostic performance than other recently reported CRISPR-based assays. | 2020-06-25 |
| 32553544 | Each UAS official website was searched between April 8 and 18, 2020, to retrieve any document, publication, or position paper on prioritization strategies regarding both diagnostic and therapeutic urological procedures, and any recommendations on the use of telemedicine and minimally invasive surgery. | 2020-06-22 |
| 32553893 | These methods, along with data management and analytic techniques, can be widely useful and shared globally. | 2020-06-22 |
| 32553908 | This retrospective single-center study includes all consecutive pregnant women with confirmed (laboratory-confirmed) or suspected (according to version 7.0 of the Chinese management guideline) COVID-19 infection, regardless of gestational age at diagnosis, admitted to the Strasbourg University Hospital (France) from March 1 to April 3, 2020. | 2020-06-21 |
| 32554043 | The results indicated that diagnostic sensitivity and specificity were 95.7 % and 98.7 %, 92.2 % and 100 % by total antibody tests and RT-PCR, respectively. […] This study supported the advantage of the combined method for detection of SARS-COV-2 with a high degree of sensitivity and specificity, as a useful tool for accurate diagnosis and timely treatment of suspected patients, epidemiological investigation, as well as monitoring ongoing outbreaks of infections with SARS-COV-2. | 2020-06-23 |
| 32554082 | Medical records of patients with COVID-19 were searched by a computer algorithm (March 1-April 15, 2020), and chart review was used to validate the diagnosis of asthma and medications prescribed for asthma. | 2020-06-21 |
| 32554284 | Ten patients with a diagnosis of relapsing-remitting MS were phoned and asked about symptoms suggestive and COVID-19 using a semi-structured questionnaire. […] The mean time since disease diagnosis was 17.30 ± 8.59 years, and all were patients with relapsing-remitting MS. | 2020-06-26 |
| 32554337 | STD onset time, recovery rate, time to recovery, hospital admission, pneumonia diagnosis, comorbidities, smoking and symptoms were analyzed. | 2020-06-19 |
| 32554619 | Expert guidelines for the diagnosis and management of IR-pneumonitis include multidisciplinary input from medical oncology, pulmonary medicine, infectious disease, and radiology specialists. […] Symptoms and imaging findings from IR-pneumonitis and COVID-19 pneumonia can be similar, and early COVID-19 viral testing may yield false negative results, complicating the diagnosis and management of both entities. […] Herein, we present a set of multidisciplinary consensus recommendations for the diagnosis and management of IR-pneumonitis in the setting of COVID-19 including: (1) isolation procedures, (2) recommended imaging and interpretation, (3) adaptations to invasive testing, (4) adaptations to the management of IR-pneumonitis, (5) immunosuppression for steroid-refractory IR-pneumonitis, and (6) management of suspected concurrent IR-pneumonitis and COVID-19 infection. | 2020-06-27 |
| 32554983 | Several studies suggest the sensitivity of chest computed tomography (CT) is far greater than that of reverse transcription polymerase chain reaction (RT-PCR) in diagnosing COVID-19 patients, and therefore, CT should be included as a primary diagnostic tool. | 2020-06-26 |
| 32555446 | In response to this epidemic, China has issued seven trial versions of diagnosis and treatment protocol for COVID-19. | 2020-06-28 |
| 32555564 | In the present position paper we collected current evidence from the literature to provide practical recommendations on the management of antithrombotic therapies (antiplatelet and anticoagulant) in various clinical contexts prevalent during the SARS-CoV-2 outbreak: in-home management of oral anticoagulant therapy; interactions between drugs used in the SARS-CoV-2 infection and antithrombotic agents; in-hospital management of antithrombotic therapies; diagnosis, risk stratification and treatment of in-hospital thrombotic complications. | 2020-06-19 |
| 32555568 | Case 2: a 76-year-old man with a diagnosis of SARS-CoV-2 pneumonia followed by pulmonary embolism 20 days later, high-resolution computed tomography on that time showed a partial resolution of crazy paving consolidation. […] These findings suggest a role for medium-long term therapeutic anticoagulation started at the time of SARS-CoV-2 pneumonia diagnosis. | 2020-06-19 |
| 32556070 | Early diagnosis of coronavirus disease 2019 (COVID-19) may help control the diffusion of the disease into the population. […] To investigate the presence of sinonasal manifestations at the onset of COVID-19 to achieve an earlier diagnosis. […] Sinonasal manifestations reported before COVID-19 diagnosis were studied with a validated questionnaire: Italian Sino-Nasal Outcome Test 22 (I-SNOT-22). […] The prevalence of sinonasal manifestations preceding COVID-19 diagnosis. […] The general practitioner may play a pivotal role in identifying potential COVID-19 in patients at an early stage if taste and/or smell alterations manifest and in suggesting quarantine before confirmation or exclusion of the diagnosis. | 2020-06-23 |
| 32556147 | Topics addressed include diagnosis, triage, and the fundamental principles of treatment with a focus on the importance of characterizing DKA severity and medical complexity to determine the best approach. | 2020-06-19 |
| 32556191 | Accurate molecular diagnostic tests are necessary for confirming a diagnosis of coronavirus disease 2019 (COVID-19). […] The numbers of available SARS-CoV-2 nucleic acid detection tests are rapidly increasing, as is the COVID-19 diagnostic literature. […] The IDSA’s goal was to develop an evidence-based diagnostic guideline to assists clinicians, clinical laboratorians, patients and policymakers in decisions related to the optimal use of SARS-CoV-2 nucleic acid amplification tests. […] In addition, we provide a conceptual framework for understanding molecular diagnostic test performance, discuss the nuance of test result interpretation in a variety of practice settings, and highlight important unmet research needs in the COVID-19 diagnostic testing space. […] The panel agreed on 15 diagnostic recommendations. […] Recognizing these limitations, the IDSA panel weighed available diagnostic evidence and recommends nucleic acid testing for all symptomatic individuals suspected of having COVID-19. | 2020-06-19 |
| 32556323 | Respiratory support includes breathing control, thoracic expansion exercises, airway clearance techniques, and respiratory muscle strength training. | 2020-06-19 |
| 32556400 | V/Q SPECT/CT can play a role in the management of patients hospitalized for COVID-19 for the diagnosis of embolic complications with meticulous hygienic precautions. | 2020-06-22 |
| 32556781 | These findings may aid future research on the diagnosis, prevention, and treatment of COVID-19 consequences. | 2020-06-22 |
| 32556788 | COVID-19 requires a radical rethink of many tenets of tracheostomy care, and controversy continues to exist regarding the optimal techniques to minimise risk to patients and healthcare workers. | 2020-06-22 |
| 32556796 | Our recommendations to better characterize the impact of these guidelines on surgical delay among vulnerable populations include the following: (1) track time from biopsy-proven diagnosis to surgery by race and ethnicity, (2) document patient and institution-related reasons for surgical delay, (3) record patient and disease-related variables/reasons for the selection of breast conservation surgery, mastectomy, and reconstruction by race and ethnicity, and (4) collect data on impactful social determinants of health such as financial reserve, housing conditions, stress, and transportation. | 2020-06-28 |
| 32556807 | At diagnosis, 143/421 (34.0%) had a normal CT. | 2020-06-22 |
| 32557183 | This paper also summarised the relevant evidence-based guidelines for the use of non-invasive and minimally invasive caries management techniques. | 2020-06-22 |
| 32557332 | Early diagnosis and individualized therapeutic management should be developed for elderly subjects based on personal medical history and polypharmacotherapy. | 2020-06-22 |
| 32557405 | With the aid of in silico techniques such as molecular docking and druggability studies, we have proposed several natural active compounds including glycyrrhizin, bicylogermecrene, tryptanthrine, β-sitosterol, indirubin, indican, indigo, hesperetin, crysophanic acid, rhein, berberine and β-caryophyllene which can be encountered as potential herbal candidate exhibiting anti-viral activity against SARS-CoV-2. | 2020-06-22 |
| 32558198 | Adding D-dimers >500 ng/mL to gender and pneumonia at CT scan in ROC curve analysis significantly increased AUC for COVID-19 diagnosis. | 2020-06-19 |
| 32558645 | One hundred and eighty-five patients (87 men, 98 women; mean age, 48.7 years), who underwent RT-PCR sampling and high-resolution CT examination in our hospital between March 15, 2020, and April 15, 2020, and got a definitive diagnosis of COVID-19 disease via initial or follow-up RT-PCR test, were included in the study. | 2020-06-19 |
| 32558646 | Because of the widespread use of CT in the diagnosis of COVID 19, indeterminate presentations such as single, few or unilateral lesions amount to a considerable number. […] We aimed to develop a new classification and structured reporting system on CT imaging (COVID-19 S) that would facilitate the diagnosis of COVID-19 in the most accurate way. […] The patients’ history, physical examination, CT findings, RT PCR, and other laboratory test results were reviewed, and a final diagnosis was made as COVID 19 or non-COVID 19. […] Chest CT scans were classified according to the COVID 19 S CT diagnosis criteria. […] Final clinical diagnosis was COVID-19 in 98 patients (12%). […] According to the COVID-19 S CT diagnosis criteria, the number of patients in the normal, compatible with COVID 19, indeterminate and alternative diagnosis groups were 581 (72.3%), 97 (12.1%), 16 (2.0%) and 109 (13.6%). […] When the indeterminate group was combined with the alternative diagnosis group, the sensitivity and specificity of COVID-19 S were 93.9% and 96.0%, with 94.8% PPV and 95.2% NPV. | 2020-06-19 |
| 32558815 | Best practices for specimen collection, transportation, testing and biosafety are addressed from the perspective of Canadian public health laboratories to ensure a consistent approach across the country: Population-based testing for COVID-19 should initially be carried out for surveillanceNasopharyngeal swab is the specimen of choice for routine testingNucleic acid amplification tests (such as real-time reverse transcription polymerase chain reaction) are the method of choice for routine testing of SARS-CoV-2The decentralization of nucleic acid amplification testing for COVID-19 to hospital or other high complexity medical laboratories should be promoted to increase test capacity and meet increased demandsIn the early stages of the pandemic, positive (approximately 10-20) and negative (approximately 50) tests by a provincial laboratory require confirmation at the National Microbiology LaboratoryCo-circulation of other viral agents associated with influenza-like Illnesses (e.g. influenza A and B and respiratory syncytial virus) should be monitored as capacity permits, as part of ongoing surveillanceOnce validated, serological testing may be utilized for assessing the presence/absence of immune response to the SARS-CoV-2 at either the population or individual level for select indications, but is likely to be of limited utility in diagnosis of acute COVID-19 illness These recommendations will be updated as new information becomes available. | 2020-06-22 |
| 32558877 | To examine whether use of ACEI/ARBs was associated with COVID-19 diagnosis and worse outcomes in patients with COVID-19. […] Patients with COVID-19 from February 22 to May 4, 2020, were identified using ICD-10 codes and followed up from day of diagnosis to outcome or end of study period (May 4, 2020). […] To examine susceptibility to COVID-19, a Cox regression model with a nested case-control framework was used to examine the association between use of ACEI/ARBs vs other antihypertensive drugs and the incidence rate of a COVID-19 diagnosis in a cohort of patients with hypertension from February 1 to May 4, 2020. […] In the nested case-control susceptibility analysis, the outcome was COVID-19 diagnosis. […] Prior use of ACEI/ARBs was not significantly associated with COVID-19 diagnosis among patients with hypertension or with mortality or severe disease among patients diagnosed as having COVID-19. | 2020-06-23 |
| 32558969 | The DOH and DCPEM, in close collaboration with the Department of Clinical Microbiology and Internal Medicine Services at Landspitali-The National University Hospital (LUH) and deCODE genetics, initiated a nationwide surveillance program for COVID-19, including diagnostic testing which began on 31 January. | 2020-06-19 |
| 32559081 | First, starting from PDB:6VSB and 6VXX, full-length S protein structures were modeled using template-based modeling, de-novo protein structure prediction, and loop modeling techniques in GALAXY modeling suite. | 2020-06-19 |
| 32560044 | A reliable diagnostic assay is crucial to early detect new COVID-19 cases and limit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission. […] Since the onset of the COVID-19 pandemic, the World Health Organization has published several diagnostic molecular approaches developed by referral laboratories, including Charité (Germany), HKU (Hong Kong), China CDC (China), US CDC (United States), and Institut Pasteur, Paris (France). […] The data presented herein are of prime importance to facilitate the equipment choice of diagnostic laboratories, as well as for the development of marketed tests. | 2020-06-22 |
| 32560091 | COVID-19 diagnosis and the prediction of virus transmission are analyzed by machine learning algorithms, simulations, and digital monitoring. | 2020-06-22 |
| 32560658 | In ICU patients, it is sometimes difficult to confirm a diagnosis of thrombosis, and curative anticoagulant treatment may also be discussed on a probabilistic basis. […] In all these situations, therapeutic doses of LMWH, or UFH in case of renal insufficiency with monitoring of anti-Xa activity, are proposed.In conclusion, intensification of heparin treatment should be considered in the context of COVID-19 on the basis of clinical and biological criteria of severity, especially in severely ill ventilated patients, for whom the diagnosis of pulmonary embolism cannot be easily confirmed. | 2020-06-23 |
| 32560694 | Multi-site screening of SARS-CoV-2 including nasal and pharyngeal swabs, stool and sputum specimens could be considered to improve the diagnosis, treatment and infection control in patients with COVID-19. | 2020-06-23 |
| 32560875 | Safety netting is a recognised General Practitioner (GP) diagnostic strategy often used in the face of uncertainty to help ensure that a patient with unresolved or worsening symptoms knows when and how to access further advice. […] Screening for Red Flags and any indication of a serious cause of symptoms is always first line in any consultation, however, clinical presentations are not always black and white with patients falling into a clear diagnostic category. | 2020-06-23 |
| 32560915 | On the 30th of April, 64 days after this first diagnosis, the number of patients had increased exponentially, reaching 19 224 confirmed cases and 1859 (9.67%) deaths. | 2020-06-23 |
| 32561220 | Therefore, finding a symptom with a high predictive value would help in diagnostic and isolation strategies. […] To correlate the sudden loss of the sense of smell in the context of the COVID-19 pandemic with results of diagnostic tests for COVID-19. […] Total or partial sudden loss of the sense of smell showed high positive predictive value for COVID-19 diagnosis, during the COVID-19 pandemic in Brazil (88.8%). | 2020-06-23 |
| 32561401 | We examined consecutive patients with lung cancer and confirmed diagnosis of COVID-19 (n=102) at a single center from March 12-May 6, 2020. | 2020-06-23 |
| 32561409 | We used SARS-CoV-2 RT-PCR and influenza virus A/B RT-PCR in respiratory samples to confirm the diagnosis. | 2020-06-23 |
| 32561491 | CT graphical diagnosis is useful for the management of penetrating craniocervical junction trauma, and it should be considered in the evaluation of patients who have suffered craniocervical penetrating injury even in the absence of major wounds or bleeding. | 2020-06-22 |
| 32561524 | We performed an audit to evaluate the impact of the COVID-19 pandemic-related delay in the diagnosis of major cancers at a Pathology Unit of a Secondary Care Hospital Network in Italy. […] CRC was identified as carrying a potentially important diagnostic delay. […] For CRC corrective procedures (continuing mass screening tests; patient triage by family physicians; diagnostic procedures alternative to colonoscopy; predictive evaluation on biopsy samples) were advised. […] Our simple audit model is widely applicable to avoid pandemic-related delay in clinical diagnosis of cancer. | 2020-06-20 |
| 32562109 | In diagnosis, chest computed tomography most commonly showed ground-glass opacity with or without consolidative patterns.Herein, we report a case of a patient affected by COVID-19 pneumonia referred in the emergency department of our institution on April 4, 2020, with peculiar lung ultrasound findings. | 2020-06-23 |
| 32562325 | Potential drivers of disparate HNC survival resulting from the pandemic include (a) differential access to telemedicine, timely diagnosis, and treatment; (b) implicit bias in initiatives to triage, prioritize, and schedule HNC-directed therapy; and (c) the marked changes in employment, health insurance, and dependent care. | 2020-06-22 |
| 32562544 | Diagnostic testing remained one of the limiting factors for early identification and isolation of infected patients. […] The agreement and diagnostic performance of POPS against NPsp were evaluated. | 2020-06-20 |
| 32562554 | We aimed to investigate the role of peripheral blood eosinophil (EOS) as a marker in the course of the virus infection to improve the efficiency of diagnosis and evaluation of COVID-19 patients. 227 pneumonia patients who visited the fever clinics in Shanghai General Hospital and 97 hospitalized COVID-19 patients admitted to Shanghai Public Health Clinical Center were involved in a retrospective research study. […] Peripheral blood EOS counts may be an effective and efficient indicator in diagnosis, evaluation and prognosis monitoring of COVID-19 patients. | 2020-06-20 |
| 32563019 | Otolaryngologists should be mindful of the symptom of anosmia in outpatients so as not to delay the diagnosis of COVID-19. | 2020-06-25 |
| 32563197 | In Italy the lack of preparation for supporting the patient load (shortage of personal protection devices, shortage of Intensive Care Unit (ICU) beds in comparison to other European Countries, and the poor early diagnostic and therapeutic activity) has led us to suggest a project that uses an online platform between General Practitioners and patients, in order to reduce moving infected individuals and to perform the diagnosis and treatment early on. | 2020-06-20 |
| 32563232 | This study reviews the associations of OGD with COVID-19 which will be useful for early diagnosis and self-isolation. | 2020-06-21 |
| 32563271 | However, some indeterminate symptoms that make diagnosis difficult, such as myalgia and fatigue, can also be seen alone, without the typical clinical picture. […] We describe a patient with COVID-19 pneumonia, the only complaint of which is myalgia, and the first diagnosis is mild rhabdomyolysis. […] Apart from the typical symptoms leading to the typical diagnosis of COVID-19 at the first admission, SARS-CoV-2 related with rhabdomyolysis should also be kept in mind. | 2020-06-21 |
| 32563273 | Furthermore, 43.2% of healthcare workers were aware of proper hand hygiene techniques. | 2020-06-21 |
| 32563494 | Future studies expected to apply more neuro-imaging techniques for CNS exploration and further explore the pathogenesis of the COVID 19 myalgia, anosmia/ageusia reported in the majority of the initial cases. | 2020-06-24 |
| 32563566 | We conducted a survey with sections addressing hospital characteristics, changes in infrastructure and resources, code stroke clinical pathways, diagnostic testing, rehabilitation, and outpatient care. […] The organisational changes made in response to the SARS-Co2 pandemic in hospitals in the Region of Madrid have modified the allocation of neurology department staff and infrastructure, stroke units and stroke care pathways, diagnostic testing, hospital admissions, and outpatient follow-up. | 2020-06-24 |
| 32563581 | The disease diagnosis became more diverse after several months, including some ready-to-treat diseases pending correct diagnosis, such as pediculosis, psoriasis, and urticaria. | 2020-06-21 |
| 32563600 | We seek to describe the medical history and clinical findings of patients attending the emergency department (ED) with suspected coronavirus disease 2019 (COVID-19) and estimate the diagnostic accuracy of patients’ characteristics for predicting COVID-19. […] We assessed diagnostic accuracy of these characteristics for COVID-19 by calculating positive and negative likelihood ratios. […] Patient-reported anosmia and the presence of bilateral B lines on lung ultrasonography had the highest positive likelihood ratio for the diagnosis of COVID-19 (7.58, 95% confidence interval [CI] 2.36 to 24.36; and 7.09, 95% CI 2.77 to 18.12, respectively). […] The absence of a high clinical probability determined by the emergency physician and the absence of bilateral B lines on lung ultrasonography had the lowest negative likelihood ratio for the diagnosis of COVID-19 (0.33, 95% CI 0.25 to 0.43; and 0.26, 95% CI 0.15 to 0.45, respectively). | 2020-06-24 |
| 32563951 | In our sample, 19.1% met the diagnostic criteria of clinical insomnia, which was twice lower than that reported in the study by Voitsidis et al., but close to those found among Chinese and Italian populations. | 2020-06-24 |
| 32563999 | This article reviews the current state of knowledge concerning the origin, transmission, diagnosis and management of coronavirus disease 2019 (COVID-19). […] The diagnosis is confirmed using reverse transcriptase PCR. | 2020-06-21 |
| 32564071 | In the first 11 days after questionnaire launch, 4039 participants (2913 women, 1118 men, 8 other, ages 19-79) reported a COVID-19 diagnosis either via laboratory tests or clinical assessment. | 2020-06-21 |
| 32564503 | On the contrary, the guidelines clearly define risk prioritisation, in terms of both potential COVID-19 exposure and the dangers associated with delayed diagnosis of anal cancers. | 2020-06-21 |
| 32564983 | The aim of the study was to describe the population and diagnoses and evaluate the main judgment criteria, defined as the ‘ability of teleconsultation to properly indicate a physical consultation for fair diagnosis and treatment in eye emergencies’. | 2020-06-25 |
| 32565126 | The spike glycoprotein structure has been completed using modeling techniques and its inner cavity, needful for the postfusion transition of the trimer, has been scanned for the identification of strongly interacting available drugs. | 2020-06-28 |
| 32565164 | In this article we will review our approach to rapidly converting an in-person diagnostic radiology elective to an entirely remote learning experience for medical students at our institution, including modification of course structure, software tools and materials utilized, and strategies for learner engagement and collaboration. | 2020-06-24 |
| 32565229 | The limitations of diagnostic tests in both sampling and testing methodologies, their validation and their relevance in interpreting data are also highlighted. | 2020-06-25 |
| 32565242 | The present study underscored the limited impact of the Covid-19 epidemic and lockdown on surgical diagnosis and cancer surgery in the Ile de France university otorhinolaryngology departments, maintaining chances for optimal survival without spreading the virus. | 2020-06-27 |
| 32565306 | Clinical molecular laboratory professionals are at the frontline of the response to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, providing accurate, high-quality laboratory results to aid in diagnosis, treatment, and epidemiology. | 2020-06-28 |
| 32565309 | The current diagnosis and medicines approach in coronavirus disease 2019 (COVID-19) does not reflect the heterogeneous characteristics of this disease. | 2020-06-25 |
| 32565366 | Even in COVID-19 epidemics, the early identification of concurrent respiratory pathogens is important to improve etiological diagnosis, preventive measures and patients’ clinical management and outcome. | 2020-06-24 |
| 32565599 | This review emphasizes on the different aspects of COVID-19 such as the epidemiology, etiopathogenesis, diagnosis, and preventive measures to be adopted in order to fight this pandemic. | 2020-06-23 |
| 32566128 | In this context, a deep reorganization of allergy clinics, in order to ensure proper diagnosis and care despite of social distancing measures expose, is needed. […] The reorganization of allergy clinics should include programmed checks for severe and poorly controlled patients, application of digital medicine service for mild-to-moderate disease in well-controlled ones, postponement of non urgent diagnostic work-ups and domiciliation of therapies, whenever possible. | 2020-06-23 |
| 32566139 | Maintaining the supply chain of pharmaceutical products is not only paramount to cover the immediate medical response but will be fundamental to reducing disruption of the healthcare delivery system, which requires constant medicines, diagnostic tools and vaccines for smooth functioning. | 2020-06-24 |
| 32566476 | Real-time polymerase chain reaction (RT-PCR) detection of severe acute respiratory syndrome coronavirus (SARS-CoV-2) is required for diagnosis of coronavirus disease 2019 (COVID-19). […] In Case 2, outpatient diagnosis was aspiration pneumonia, but clinical suspicion remained high for COVID-19 at hospitalization based on epidemiological and clinical features. | 2020-06-23 |
| 32566559 | Computed tomography (CT) has been widely used in the diagnosis of this novel pneumonia. […] This study aims to understand the role of CT for the diagnosis and the main imaging manifestations of patients with COVID-19. […] We conducted a rapid review and meta-analysis on studies about the use of chest CT for the diagnosis of COVID-19. […] In conclusion, this meta-analysis indicated that chest CT scan had a high sensitivity in diagnosis of patients with COVID-19. […] Therefore, CT can potentially be used to assist in the diagnosis of COVID-19. | 2020-06-23 |
| 32566574 | The incubation period of these confirmed patients with imported COVID-19 was 17.6 days (IQR 5-34 days) and the median time from symptom onset to diagnosis was 145.64 h (IQR 21-441 h). | 2020-06-23 |
| 32566620 | Those parameters with significant differences between moderate and severe cases were analyzed, and the combination parameters with the best diagnostic performance were selected using the linear discriminant analysis (LDA) method. […] The combined parameters of NLR and RDW-SD had the best diagnostic efficiency (AUC =0.938), and when the cutoff value was 1.046, the sensitivity and the specificity were 90.0% and 84.7% respectively, followed by the combined parameter NLR&RDW-CV (AUC =0.923). | 2020-06-23 |
| 32566934 | Additionally, this might augment and refine diagnosis and prognostic management as well as treatment. | 2020-06-23 |
| 32567006 | In the absence of a virus nucleic acid real-time reverse transcriptase-polymerase chain reaction (RT-PCR) test and experienced radiologists, clinical diagnosis is challenging for viral pneumonia with clinical symptoms and CT signs similar to that of coronavirus disease 2019 (COVID-19). | 2020-06-25 |
| 32567041 | They were contacted after the quarantine period to inquire about symptoms consistent with COVID-19, and the results of diagnostic test for SARS-CoV-2 when performed. | 2020-06-25 |
| 32567580 | Normal, borderline, and HADS-A scores consistent with a diagnosis of anxiety were reported by 423 (36.6%), 174 (15.1%), and 559 (48.4%) patients, respectively. | 2020-06-22 |
| 32567656 | For healthcare providers, specifically military and federal public health personnel, prompt and accurate diagnosis and isolation of SARS-CoV-2 novel coronavirus patients provide a two-fold benefit: (1) directing appropriate treatment to the infected patient as early as possible in the progression of the disease to increase survival rates and minimize the devastating sequelae following recovery and remission of symptoms; (2) provide critical information requirements that enable commanders and public health officials to best synchronize policy, regulations, and troop movement restrictions while best allocating scarce resources in the delicate balance of risk mitigation versus mission readiness. | 2020-06-22 |
| 32568026 | With proper AI based approaches, we will be definitely benefited with rapid diagnosis of disease, early warnings, fastening drug development processes and proper social control measures during this pandemic. | 2020-06-22 |
| 32568167 | To formulate standardized scoring criteria and an objective quantization standard to guide decision making in detection and diagnosis of COVID-19 virus induced pneumonia in clinical practice. […] Key indicators of differential diagnosis were identified in relevant literature and the scores were quantified namely, patients with more than 8 points were identified as high risk, those with 6-8 points as moderate risk, and those with fewer than 6 points as low risk for COVID-19 virus. […] Diagnostic sensitivity and specificity were subsequently calculated. | 2020-06-22 |
| 32568341 | As a result, our fast and easy LFIAs could provide a preliminary test result for physicians to make the correct diagnosis of SARS-CoV-2 infections along with alternative testing methods and clinical findings, as well as seroprevalence determination, especially in low-resource countries. | 2020-06-22 |
| 32568401 | Diagnosis with COVID-19 was confirmed when throat swab samples tested positive for severe acute respiratory syndrome coronavirus 2 on reverse transcription-polymerase chain reaction. | 2020-06-25 |
| 32568413 | The serological testing of anti-SARS-CoV-2 IgG and/or IgM is widely used in the diagnosis of COVID-19. […] However, its diagnostic efficacy remains unclear. […] In this study, we searched diagnostic studies from Web of Science, PubMed, Embase, CNKI, Wanfang databases to calculate the pooled diagnostic accuracy measures using bivariate random-effects model meta-analysis. […] A subgroup analysis among detection methods indicated the sensitivity of IgG and IgM using ELISA were slightly lower than those using gold immunochromatography assay (GICA) and chemiluminescence immunoassay (CLIA) (p > .05) These results showed that the detection of anti-SARS-CoV-2 IgG and IgM had high diagnostic efficiency to assist the diagnosis of SARS-CoV-2 infection. | 2020-06-22 |
| 32568496 | To describe the recommendations for diagnosis, treatment and follow-up of patients with TC amidst COVID- 19 pandemic. […] The biology of TC requires immediate care of patients during diagnosis, initial surgical therapy and management of recurrent disease. | 2020-06-22 |
| 32568497 | Histological diagnosis with local staging is necessary before offering any therapeutic option. | 2020-06-22 |
| 32568498 | This review discusses the impact of COVID-19 in Female Urology, revises the most important disorders in this field and how their diagnosis and treatment may be modified due to the current pandemic. | 2020-06-22 |
| 32568543 | Mass spectrometry (MS) can deliver valuable diagnostic data that complement genomic information and allow us to increase our current knowledge of the COVID-19 disease caused by the SARS-CoV-2 virus. […] Building on these promising initial results, faster MS protocols can now be developed as routine diagnostic tools for COVID-19 patients. | 2020-06-26 |
| 32568662 | Nearly 20% of patients remained in the CTCs for 4 weeks after diagnosis. | 2020-06-22 |
| 32568663 | The mean time patients remained at CTCs was 19.6 days (SD +5.8 days) from the day of diagnosis until our study ended on March 23, 2020. | 2020-06-22 |
| 32568675 | The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. […] Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. […] Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages. | 2020-06-25 |
| 32568676 | Fast diagnostic methods can control and prevent the spread of pandemic diseases like coronavirus disease 2019 (COVID-19) and assist physicians to better manage patients in high workload conditions. […] Although a laboratory test is the current routine diagnostic tool, it is time-consuming, imposing a high cost and requiring a well-equipped laboratory for analysis. […] However, the performance of radiologists in diagnosis of COVID-19 was moderate. […] In this study is suggested a rapid and valid method for COVID-19 diagnosis using an artificial intelligence technique based. | 2020-06-25 |
| 32568687 | It is also in part an introductory review to relevant computational techniques for tackling viral threats, using COVID-19 as an example. | 2020-06-25 |
| 32568722 | To describe the epidemiological features and clinical symptoms of patients receiving remote diagnosis and treatment at the online outpatient clinic of our hospital during the coronavirus disease 2019 (COVID-19) outbreak, and to analyze the outcomes and advantages of telemedicine during the COVID-19 pandemic. […] All patients receiving remote diagnosis and treatment and consultation services over COVID-19 concerns at the online outpatient clinic of Henan Provincial People’s Hospital from January 24 to February 17, 2020, were collected. […] A total of 4,589 patients receiving remote diagnosis and treatment were recruited. […] Remote diagnosis and treatment offered via the online outpatient consultation effectively reduce the burden on hospitals, prevent overcrowding, reduce the risk of cross-infection and relieve patients’ anxiety during the COVID-19 outbreak, which play an essential role in the pandemic management. | 2020-06-22 |
| 32568727 | Through the comparison of monitored symptoms between hospitalized and non-hospitalized patients, this study found the prolonged persistence and deterioration of fever, dyspnea, lack of strength, and muscle soreness to be diagnostic for identifying patients for hospitalization. | 2020-06-24 |
| 32568730 | Thus, it is crucial to accelerate the development of an artificial intelligence (AI) diagnostic tool to support physicians. […] For the test dataset, the diagnostic performance to diagnose COVID-19 pneumonia was compared among the four pre-trained FCONet models. […] Of the four pre-trained models of FCONet, the ResNet50 showed excellent diagnostic performance (sensitivity 99.58%, specificity 100%, and accuracy 99.87%) and outperformed the other three pre-trained models in testing dataset. […] The FCONet, a simple 2D deep learning framework based on a single chest CT image, provides excellent diagnostic performance in detecting COVID-19 pneumonia. | 2020-06-22 |
| 32568741 | Cardiac injury on admission is associated with worse clinical outcome and higher mortality risk in COVID-19 patients including patients free of previous CAD diagnosis. | 2020-06-22 |
| 32569358 | In this study, we addressed the challenge of automating the normalization of COVID-19 diagnostic tests, which are critical data elements, but for which controlled terminology terms were published after clinical implementation. | 2020-06-22 |
| 32569419 | The survey incorporated items from validated stress scales and assessed perceptions and key elements in the following domains: numbers of suspected COVID-19 patients, availability of diagnostic testing, levels of home and workplace anxiety, severity of work burnout, identification of stressors, changes in home behaviors, and measures to decrease provider anxiety. | 2020-06-22 |
| 32569494 | In a cross-sectional, observational study all consecutive patients with confirmed COVID-19 diagnosis at the central referral center of these patients in northeast of Iran were included. […] Hence, it seems important to involve ophthalmologist in the diagnosis and management of these patients. | 2020-06-22 |
| 32569585 | In this prospective, feasibility, cohort study, patients aged 18-75 years with a confirmed diagnosis of COVID-19-related pneumonia receiving supplemental oxygen or non-invasive continuous positive airway pressure were recruited from San Gerardo Hospital, Monza, Italy. | 2020-06-25 |
| 32569591 | While advancements in other diagnostic modalities have allowed for more efficient and accurate diagnosis, the stethoscope has evolved in parallel to address the needs of the modern era of medicine. […] These advancements include sound visualization, ambient noise reduction/cancellation, Bluetooth™ transmission, and computer algorithm diagnostic support. | 2020-06-25 |
| 32569631 | Heating-activation does not decrease the diagnostic efficacy of SARS-CoV-2 IgM or IgG antibodies. | 2020-06-25 |
| 32569835 | Among symptomatic workers, the key symptoms to guide diagnosis are taste and smell alterations and fever. | 2020-06-25 |
| 32569904 | We obtained information on the scale of population migrated from Wuhan, the world epicentre of the COVID-19 outbreak, into the study provinces/municipalities using mobile-phone positioning system and big data techniques. | 2020-06-25 |
| 32570016 | The CIoMT platform enables real-time tracking, remote health monitoring, rapid diagnosis of the cases, contact tracking, clustering, screening, and surveillance thus, reducing the workload on the medical industry for prevention and control of the infection. […] CIoMT is a promising technology for rapid diagnosis, dynamic monitoring and tracking, better treatment and control without spreading the virus to others. | 2020-06-26 |
| 32570045 | The emergence of a new coronavirus in Wuhan China has triggered a global need for accurate diagnostic assays. | 2020-06-26 |
| 32570113 | Neurologic manifestations of COVID-19 are highly variable and can occur prior to the diagnosis of or as a complication of the viral infection. | 2020-06-22 |
| 32570265 | Lung ultrasound (LUS) is an accurate, safe, and cheap tool assisting in the diagnosis of several acute respiratory diseases. […] The diagnostic value of LUS in the workup of coronavirus disease-19 (COVID-19) in the hospital setting is still uncertain. […] When integrated with clinical data, LUS could represent a valid diagnostic aid in patients with suspect COVID-19 pneumonia, which reflects CT findings. | 2020-06-22 |
| 32570810 | At present, confirmatory diagnosis is by reverse transcription polymerase chain reaction (RT-PCR), typically taking several hours and requiring a molecular laboratory to perform. […] It could enable wider use of Covid-19 testing for diagnosis, screening, and research in countries and regions where laboratory capabilities are limiting. | 2020-06-25 |
| 32571147 | Furthermore, it is critical to respect the continuing importance of flexible laryngoscopy in diagnosis. […] As algorithms evolve, time-honored approaches for diagnosis and management of acute airway pathology remain essential in ensuring patient safety. | 2020-06-23 |
| 32571228 | Grasping the clinical and CT features stratified by age will be helpful for early definite diagnosis of COVID-19. | 2020-06-25 |
| 32571605 | Para-clinical investigations including laboratory tests and radiologic findings play an important role in early diagnosis and treatment monitoring of COVID-19. | 2020-06-25 |
| 32571612 | The WHO has just released guidance for people in self-quarantine, those without any symptoms or diagnosis of acute respiratory illness, which provides practical advice on how to stay active and reduce sedentary behavior while at home. | 2020-06-25 |
| 32571651 | Bedside chest ultrasonography, when integrated with clinical data, is an accurate tool for improving the diagnostic process of many respiratory diseases. […] A diagnosis of suspect COVID-19 pneumonia was made in 44 patients, and 6 of them required hospitalization. […] In nursing home residents, screening of COVID-19 pneumonia with bedside chest ultrasonography is feasible and may represent a valid diagnostic aid for an early detection of COVID-19 outbreaks and adequate patient management. | 2020-06-25 |
| 32571661 | The diagnosis was made based on a suspicious case (63.4%) and a probable case (12.3%). | 2020-06-25 |
| 32571677 | Different methodologies and recommendations on contact tracing for Primary Health Care (PHC) and Public Health Services (PHS), like articles in Pubmed about COVID-19 and contact tracing, official contact definitions, the classic contact tracing model in tuberculosis (TB), information about apps for contact tracing and the role of the diagnostic tests, were reviewed. […] To establish efficient prevention and control measures, it is always necessary to implement contact tracing based on clinical suspicion, early diagnosis and isolation of cases and contacts and their follow-up. | 2020-06-25 |
| 32571747 | During the study period, among 205 diagnostic CT examinations, six examinations (6/205, 3%) in 6 different patients (4 men, 2 women; median age, 57 years) revealed images highly suggestive of COVID-19 pneumonia. […] The final diagnosis was confirmed by RT-PCR. […] Cumulative incidence of fortuitous diagnosis if COVID-19 pneumonia did not exceed 3% during the highest pandemic phase and was predominantly associated with limited lung involvement. | 2020-06-25 |
| 32571748 | Artificial intelligence could assist radiologists for diagnosis and prognosis evaluation. | 2020-06-25 |
| 32571894 | In response, many diagnostic manufacturers have developed molecular assays for SARS-CoV-2 under the Food and Drug Administration (FDA) Emergency Use Authorization (EUA) pathway. | 2020-06-23 |
| 32571972 | Baseline characteristics, clinical presentation, management of immunosuppressive therapy and outcomes were collected. 57 patients were included (70% male, median (IQR) age at diagnosis 65 (57-70) years). 21 (37%), 32 (56%) and 21 (37%) patients had one cardiovascular disease, arterial hypertension and diabetes mellitus, respectively. | 2020-06-26 |
| 32572154 | The availability of digital pathology systems can facilitate remote microscopic diagnosis, although formal comprehensive (case-based) validation of remote digital diagnosis has not been reported. […] Intraobserver concordance metrics included reporting elements of top-line diagnosis, margin status, lymphovascular and/or perineural invasion, pathology stage, and ancillary testing. […] Major diagnostic equivalency was 100% between digital and glass slide diagnoses; and overall concordance was 98.8% (251/254). […] This study reports validation of primary diagnostic review and reporting of complete pathology cases from a remote site during a public health emergency. […] Our experience shows high (100%) intraobserver digital to glass slide major diagnostic concordance when reporting from a remote site. | 2020-06-27 |
| 32572532 | A group of 29 international experts reviewed current insights into the epidemiology, diagnosis and management of IAPA and proposed a case definition of IAPA through a process of informal consensus. […] A consensus case definition of IAPA is proposed, which will facilitate research into the epidemiology, diagnosis and management of this emerging acute and severe Aspergillus disease, and may be of use to study CAPA. | 2020-06-25 |
| 32572561 | To assess the impact of the Covid-19 pandemic on FDG-PET/CT work volume and to evaluate the occurrence of abnormal imaging findings suspicious or potentially diagnostic for interstitial pneumonia by Covid-19 infection in south Italy. | 2020-06-25 |
| 32572861 | Results The toolkit consists of four cognitive aids that can be used to support team huddles, briefings and debriefs, alongside techniques to optimise endoscopic non-technical skills across the patient procedure pathway. | 2020-06-23 |
| 32573207 | Challenges and issues of molecular diagnosis of COVID-19 have captured the world’s attention. […] Analytical challenges directly impact the speed and validity of molecular diagnosis, raising concerns over clinical sensitivity and specificity. […] In this Perspective, we discuss strategies for molecular diagnosis of COVID-19, highlight challenges of detecting SARS-CoV-2 virus, and identify opportunities to assist in finding solutions to these challenges. | 2020-06-23 |
| 32573331 | There was a decrease of 14% (RR 0.85, OR 0.20, p = 0.006) in aerosol-generating anesthetic techniques used.Interpretation - The impact of the COVID-19 pandemic has led to a decline in the number of acute trauma referrals, admissions (but increased risk and odds ratio), operations, and aerosolizing anesthetic procedures since implementing social distancing and lockdown measures during the “golden month.” | 2020-06-23 |
| 32573469 | However, swabs sampling is a critical step, and especially in case of low viral load, might be a potential source of diagnostic errors. | 2020-06-23 |
| 32573713 | Risk of bias and applicability concern was evaluated using the Quality Assessment of Diagnostic Accuracy Studies -2. 45 studies were included, of which 21 publications were used for the meta-analysis. | 2020-06-23 |
| 32574250 | A systematic review and meta-analysis of these studies are required to understanding the neurologic characteristic of the disease and help physicians with early diagnosis and management. Objective: To conduct a systematic review and meta-analysis on the neurologic characteristics in patients with COVID-19. Evidence Review: Authors conducted a literature search through PubMed from January 1st, 2020 to April 8th, 2020. | 2020-06-23 |
| 32574261 | Therefore, there is urgent need to characterize the virus and the viral-mediated responses, in order to develop specific diagnostic and therapeutic tools to prevent viral transmission and efficiently cure COVID-19 patients. | 2020-06-26 |
| 32574287 | Definitive diagnosis can be made by a history of contact with a proven case, fever, pneumonia and gastrointestinal disorder and a Polymerase chain reaction (PCR) test of nasopharyngeal swabs. | 2020-06-23 |
| 32574292 | This article reviews the epidemiology, pathogenesis, clinical manifestations, diagnosis, and treatment methods of severe COVID-19 and puts forward some tentative ideas, aiming to provide some guidance for the diagnosis and treatment of severe COVID-19. | 2020-06-23 |
| 32574297 | The aim of the present study was to help clinicians gain a better understanding about differences between Influenza virus pneumonia and COVID-19 by comparative analysis of the early-stage clinical features. Methods: Clinical data of patients with confirmed diagnosis of COVID-19 and influenza A pneumonia identified in our hospital were collected and analyzed retrospectively to identify the clinical features that could differentiate between the two types of viral pneumonia. Results: The two types of viral pneumonia mainly affected adults, especially people over 50 years, with no gender difference between them. […] Blood routine test has a limited diagnostic value in differentiating the two forms of pneumonia. | 2020-06-23 |
| 32574316 | The deleterious effects of coronavirus have prompted the development of diagnostic tools to manage the spread of disease. […] Point-of-care (POC) biosensors, including chip-based and paper-based biosensors are typically low-cost and user-friendly, which offer tremendous potential for rapid medical diagnosis. | 2020-06-23 |
| 32574326 | In this original research article, we describe the conception, the analytical and clinical performances as well as the risk management of implementing the COVID-19 Ag Respi-Strip in a diagnostic decision algorithm. Materials and Methods: Development of the COVID-19 Ag Respi-Strip resulted in a ready-to-use ICT assay based on a membrane technology with colloidal gold nanoparticles using monoclonal antibodies directed against the SARS-CoV and SARS-CoV-2 highly conserved nucleoprotein antigen. […] User-friendliness analysis and risk management assessment through Ishikawa diagram demonstrate that COVID-19 Ag Respi-Strip may be implemented in clinical laboratories according to biosafety recommendations. Conclusion: The COVID-19 Ag Respi-Strip represents a promising rapid SARS-CoV-2 antigen assay for the first-line diagnosis of COVID-19 in 15 min at the peak of the pandemic. […] Its role in the proposed diagnostic algorithm is complementary to the currently-used molecular techniques. | 2020-06-23 |
| 32574328 | The objective of this systematic review was to characterize the clinical, diagnostic, and treatment characteristics of hospitalized patients presenting with COVID-19. Methods: We conducted a structured search using PubMed/Medline, Embase, and Web of Science to collect both case reports and case series on COVID-19 published up to April 24, 2020. | 2020-06-23 |
| 32574333 | Therefore, we have analyzed the seven versions of China’s national guidelines to examine how the diagnostic criteria roadmap has developed and evolved, in order to share our experience worldwide. […] A nucleic acid test is currently accepted as the gold standard method to confirm diagnosis. […] In addition, imaging examination and epidemiological history should also be considered as auxiliary diagnosis methods. | 2020-06-23 |
| 32574334 | The interval between disease onset and diagnosis was 8.5 days (IQR, [4-11]). | 2020-06-23 |
| 32574337 | This paper reports the clinical characteristics, diagnosis, and treatment of the first critical COVID-19 patient in Liaocheng City, who was admitted to the intensive care unit isolation ward of Liaocheng People’s Hospital on February 11, 2020. […] The purpose of this case report is to provide a reference for the clinical diagnosis and treatment of critical COVID-19 patients. | 2020-06-23 |
| 32574691 | We report a patient with the diagnosis of infective endocarditis concomitant COVID-19 and reporting the main outcome, diagnostic, and management of this disease. | 2020-06-25 |
| 32574709 | GrA+CD8+ T and perforin+ NK cells had good sensitivity and specificity for assisting diagnosis of COVID-19. […] GrA+CD8+ T and perforin+ NK cells might be used as meaningful indicators for assisting diagnosis of COVID-19. | 2020-06-25 |
| 32575505 | The present study aims to assess the SARS-CoV-2 infection rate amongst HWs in a teaching hospital in Central Italy and the diagnostic performance of SARS-CoV-2 serology (index test) in comparison with the SARS-CoV-2 RNA PCR assay (reference standard). […] IgG serology showed a higher diagnostic performance when performed at least two weeks after testing SARS-CoV-2-positive at the RNA RT-PCR assay by a nasopharyngeal swab. […] IgM serology does not seem to be a useful test for the diagnosis of active SARS-CoV-2 infection. | 2020-06-26 |
| 32575728 | Meanwhile, increased demand for testing has led to a shortage of reagents and supplies and compromised the performance of diagnostic laboratories in many countries. […] We identified an M-gene binding primer and probe pair highly suitable for the quantitative detection of SARS-CoV-2 RNA for diagnostic and research purposes. | 2020-06-24 |
| 32575786 | Elucidating the changes in hematological parameters in SARS-CoV-2 infected patients could help to understand the pathophysiology of the disease and may provide early clues to diagnosis. | 2020-06-24 |
| 32576055 | Our review yielded in 10 categories (i) the risk of diagnostic procedures in suspected mothers on fetus/infant health, (ii) the risk of intrauterine or postpartum transmission to the fetus/infant, (iii) appropriate method and delivery time in women with confirmed COVID-19, (iv) umbilical cord clamping and skin to skin contact, (v) clinical manifestations of infected infants, (vi) confirmation of infection in a suspected neonate/infant, (vii) instructions for infant’s care and how to feed her/him, (viii) bathing the baby, (ix) the criteria of discharging baby from the hospital, (x) the impact of isolation on the maternal mental health.Results: Our findings showed that the possibility of intrauterine or perinatal transmission of COVID-19 is still questionable and ambiguous. | 2020-06-24 |
| 32576057 | On April 6, 2020, the Child Neurology Society issued an online statement of immediate recommendations to streamline diagnosis and treatment of infantile spasms with utilization of telemedicine, outpatient studies, and selection of first-line oral therapies as initial treatment. | 2020-06-26 |
| 32576224 | All the patients received the positive diagnosis of SARS-CoV-2 infection. […] CT features can play an important role in the early diagnosis and follow-up of COVID-19 patients. | 2020-06-26 |
| 32576232 | Some features of a computed tomography scan of her chest and her clinical history with known dysphagia had led at first to a different diagnosis with a consequent exposure of health professionals to infectious risk in two distinct hospitals. […] In this case report, we describe the clinical/imaging features of coronavirus disease 2019 pneumonia and the diagnostic process that led to a correct diagnosis in a nonagenarian with multiple comorbidities. | 2020-06-26 |
| 32576329 | Patients diagnosis, interventions, adverse events and early post-procedural courses were studied. […] Thirty-one patients with various diagnosis of congenital cardiovascular disorders were retrospectively reviewed. | 2020-06-24 |
| 32576346 | The diagnostic value of WBC, NEU, LYM, IL-6, D-dimer and NLR on COVID-19 classification was evaluated by the receiver operating characteristic (ROC) curve. […] The AUC of NLR was the highest, which was of high diagnostic value; when the optimum cut-off value of NLR was 3.00, the sensitivity was 100%, and the specificity was 73.1%. | 2020-06-24 |
| 32576508 | As for many respiratory viruses-caused diseases, diagnosis of COVID-19 relies on two main compartments: clinical and paraclinical diagnostic criteria. […] Rapid and accurate diagnosis is vital in such a pandemic. […] In this review, we shed light on the most used and the most validated diagnostic tools. […] Furthermore, we intend to include few under-development techniques that may be potentially useful in this context. […] The practical intent of our work is to provide clinicians with a realistic summarized review of the essential elements in the applied paraclinical diagnosis of COVID-19. | 2020-06-26 |
| 32577087 | In over 90% of non-COVID-19 cases, the alternative diagnosis was respiratory. […] This study highlights the difficulty in diagnosing COVID-19 on clinical grounds and the importance of diagnostic capacity in all settings. | 2020-06-25 |
| 32577325 | More trials and studies should be conducted to analyze the impact of early diagnosis of infection in children and its management. | 2020-06-25 |
| 32577428 | Posterior oropharyngeal saliva is increasingly recognized as a valid respiratory specimen for SARS-CoV-2 diagnosis. […] The optimal timing of collection is currently unknown, and we speculate that an early-morning specimen before oral hygiene and breakfast would increase the diagnostic yield. | 2020-06-25 |
| 32577869 | The aim of this case series is to describe our experience in diagnosis and management of oncological asymptomatic patients with COVID-19 who underwent 18F-FDG PET/CT. | 2020-06-26 |
| 32578027 | Hence, there is a critical need to discover alternative techniques to cope with the current scenario. | 2020-06-26 |
| 32578309 | Careful dermatological examination improves diagnostic accuracy in skin disorders and skin manifestations of COVID-19 infection that provides an early diagnosis and treatment, helps to improve the quality of the patient care and management. | 2020-06-24 |
| 32578378 | COVID-19 diagnosis relies upon nucleic acid detection; however, currently recommended methods exhibit high false-negative rates and are unable to identify other respiratory virus infections, thereby resulting in patient misdiagnosis and impeding epidemic containment. […] NTS is thus suitable for COVID-19 diagnosis; moreover, this platform can be further extended for diagnosing other viruses and pathogens. | 2020-06-24 |
| 32578687 | Its diagnosis of certainty is given by polymerase chain reaction. | 2020-06-24 |
| 32578826 | Chest computed tomography, despite being highly sensitive, has a low specificity, and hence cannot replace the reference diagnostic test (reverse transcription polymerase chain reaction). | 2020-06-24 |
| 32578829 | Due to the scarcity of relevant data, discussions based on disease stage, evaluation of surgical treatment, radiotherapy techniques, systemic therapy, follow-up, and supportive care were carried out, and specific suggestions issued. | 2020-06-24 |
| 32578859 | Using nationwide Danish registries, we included all patients, aged 18-90 years, receiving a new-onset AF diagnosis during the first 3 months of 2019 and 2020. | 2020-06-24 |
| 32578933 | In this article, we will describe three lung ultrasound algorithms for the emergency diagnosis of patients presenting with respiratory symptoms during a COVID-19 pandemic: (i) LUSC19: lung ultrasound to assess the severity of COVID-19; (ii) LUSAC: lung ultrasound to exclude alternative causes of respiratory distress; and (iii) LUSI: lung ultrasound following intubation. | 2020-06-25 |
| 32579076 | The Pre-triage check-points identify any potential COVID-19-infected patients and re-direct them to the main Triage area where trained medical staff screen which patients undergo diagnostic testing. | 2020-06-24 |
| 32579236 | CONCLUSIONS: We obtained reliable estimates of the chest CT manifestations of COVID-19 pneumonia patients, which might provide an important clue for the diagnosis and classification of COVID-19 pneumonia. | 2020-06-24 |
| 32579256 | To evaluate the presence of viral RNA of SARS-CoV-2 in conjunctival swab specimen of COVID-19 patients with and without conjunctivitis to establish the diagnostic value of reverse transcription-polymerase chain reaction (RT-PCR) in each case and to describe its clinical characteristics. | 2020-06-24 |
| 32579877 | We found that serologic diagnostic testing was positive for 71% (5/7) of completely asymptomatic patients, but neutralizing antibody response occurred in all 7 patients. | 2020-06-24 |
| 32579983 | In hospitals this leads to poor patient flow and nosocomial transmission and so rapid, accurate diagnostic tests are urgently required. […] We performed a real-world diagnostic accuracy study of FebriDx in hospitalised patients during the first wave of the pandemic. […] Measures of diagnostic accuracy were calculated based on FebriDx results compared to the reference standard of SARS-CoV-2 PCR on combined nose and throat swabs. | 2020-06-26 |
| 32579986 | In this article the use of laboratory biomarkers is discussed with regard to their use for diagnosis, disease progression, and risk assessment. | 2020-06-26 |
| 32580215 | The patient was given NIMV (non-invasive mechanical ventilation), and hydroxychloroquine, favipiravir and azithromycin in isolation intensive care, with the diagnosis of severe pneumonia. […] We believe that the clinical course and pathology findings obtained after right pneumonectomy in a patient with pre-symptomatic COVID-19 pneumonia will guide the diagnosis and treatment of patients infected with SARS-CoV-2. | 2020-06-24 |
| 32580529 | We focus on the serogical immunoassay for diagnosis of Covid-19 as an important weapon not only for diagnostic purpose, but also for epidemiologic one. | 2020-06-25 |
| 32580531 | The objective of the study was to conduct a follow-up investigation of 10 asymptomatic patients at diagnosis among the 98 confirmed COVID-19 cases reported in Busan between February 21 and March 13, 2020 to determine whether asymptomatic infection and transmission during asymptomatic period are possible. […] Among the 98, confirmed COVID-19 cases reported in Busan, the study analyzed 10 (10.2%) asymptomatic patients at diagnosis. […] The Results confirmed that two (2.0%) patients reported to be asymptomatic during the initial epidemiological investigation, but turned symptomatic before diagnosis as per the in-depth interview results. […] Four cases (4.0%) of early detection led to confirmed diagnosis during the incubation period and presentation of symptoms after diagnosis. | 2020-06-25 |
| 32580532 | In Scenario 3, it was possible to effectively suppress the infectious disease even with a relatively slow rate of diagnosis and relatively high infection rate. | 2020-06-25 |
| 32580796 | The purpose of this research was to investigate coronavirus disease (COVID-19) susceptibility in districts of Bangladesh using multicriteria evaluation techniques. | 2020-06-25 |
| 32580948 | Clinical and analytical performance of the test were validated in an observational study using residual samples (>1500) with positive or negative COVID-19 diagnosis. […] The assay’s diagnostic sensitivity was 91.3% and 95.7% at >5 or ≥15 days from diagnosis, respectively, and 100% when assessed against a neutralizing assay. | 2020-06-25 |
| 32580969 | Early diagnosis by real-time PCR and next-generation sequencing has facilitated the identification of the pathogen at an early stage. […] In this review, we address epidemiological, diagnostic, clinical, and therapeutic aspects, including perspectives of vaccines and preventive measures that have already been globally recommended to counter this pandemic virus. | 2020-06-25 |
| 32581069 | Within this framework, it is crucial to ensure no disruption to essential oncological services and guarantee the optimal care.This is a structured proposal for the management of lung cancer, comprising three levels of priorities, namely: tier 1 (high priority), tier 2 (medium priority) and tier 3 (low priority)-defined according to the criteria of the Cancer Care Ontario, Huntsman Cancer Institute and Magnitude of Clinical Benefit Scale.The manuscript emphasises the impact of the COVID-19 pandemic on lung cancer care and reconsiders all steps from diagnosis, staging and treatment.These recommendations should, therefore, serve as guidance for prioritising the different aspects of cancer care to mitigate the possible negative impact of the COVID-19 pandemic on the management of our patients.As the situation is rapidly evolving, practical actions are required to guarantee the best patients’ treatment while protecting and respecting their rights, safety and well-being. | 2020-06-25 |
| 32581183 | Therefore, an alternative noninvasive sample for diagnostic of emerging viral diseases is required. | 2020-06-26 |
| 32581324 | To investigate the diagnostic value of the temporal radiographic changes, and the relationship to disease severity and viral clearance in COVID-19 patients. | 2020-06-27 |
| 32582134 | The communication between the microbiota and SARS-CoV-2 and the role of this association in diagnosis and treatment are unclear. | 2020-06-26 |
| 32582307 | The cross-sectional descriptive study (late March-2020 to mid of April-2020) was conducted at Diagnostic & Research Laboratory LUMHS Jamshoro / Hyderabad. […] The study explored the data of the suspected and diagnosed (confirmed) case of COVID-2019 (Tablighi Jamaat and Zaireen) reported by Diagnostic Research Laboratory Liaquat University of Medical and Health Sciences (LUMHS) Jamshoro who belonged to various parts of the country in general and province Sindh in particular. […] RT-PCR measure allowed fast, delicate, and explicit discovery of SARS-CoV in biochemical diagnosis. | 2020-06-26 |
| 32582312 | Fear included, infecting family members 177(79.7%), rapid spread of disease 140(63%), complications of disease 134(60.3%), becoming a carrier in 64(28.8%) and 62(27.9%) feared missing the diagnosis. | 2020-06-26 |
| 32582316 | Brief Resilience Scale, Short General Self Efficacy Scale, Brief Scale for Social Support, Risk Behavior Diagnostic Scale and Brief Self-Control Scale. | 2020-06-26 |
| 32582323 | Major factors for infection among HCWs include lack of understanding of the disease, inadequate use and availability of Personal Protective Equipment (PPE), uncertain diagnostic criteria, unavailability of diagnostic tests and psychological stress. | 2020-06-26 |
| 32582330 | Patients usually have respiratory symptoms but gastrointestinal and hepatic dysfunction are not uncommon presentations and can lead to a delay in diagnosis and management. | 2020-06-26 |
| 32582332 | There is some discrepancy between the governmental guidelines, professional Societies and Radiology and Respiratory Medicine specialists with divided opinions between the use of the chest X-rays and CT scan, and whether the use be screening or diagnostic. | 2020-06-26 |
| 32582598 | This report shows the possibility of misdiagnosis or missed diagnosis of children with COVID-19. | 2020-06-26 |
| 32582718 | The outbreak and spread of COVID-19 worldwide, highlights the critical need for developing rapid and accurate diagnostic testing methods for emerging human coronavirus (CoV) infections. […] The key components of viral diagnostic tests are (1) collection of the appropriate sample (blood, nasal swab, and throat swab), (2) availability of the genetic and proteomic sequences of the novel virus for analysis, and (3) rapid and accurate laboratory testing methods. […] The current gold standard for the molecular diagnosis of SARS-CoV-2 infection is the real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for the qualitative and quantitative detection of viral nucleic acids. […] The challenges faced in developing a diagnostic test for a novel pathogen are the ability to measure low viral loads for early detection, to provide low or no cross-reactivity with other viral strains and to deliver results rapidly. […] Several point-of-care molecular devices are currently being integrated for fast and accurate diagnosis of SARS-CoV-2 infections. | 2020-06-26 |
| 32582719 | In this review, we highlight the etiology, epidemiology, pathogenesis and pathology, clinical characteristics, diagnosis, clinical management, prognosis, infection control and prevention of COVID-19 based on recent studies. | 2020-06-26 |
| 32582747 | Poor responses from the authorities to the spread of infection, lack of effective measures for prevention, unavailability of promising treatment options, and sufficient diagnostic options have created an alarming for the world. […] Implementing proper strategies addressing the infection control and clinical supplies, understanding the mechanism associated with pathogenesis, advancing in preventive measures and effective treatment and diagnostic options are necessary to control the ongoing pandemic. | 2020-06-26 |
| 32582748 | Background: Since the Covid-19 global pandemic emerged, developing countries have been facing multiple challenges over its diagnosis. | 2020-06-26 |
| 32582818 | It has been well documented from the early days of the 2019 novel coronavirus (COVID-19) pandemic that patients with a diagnosis of cancer are not only at higher risks of contracting a COVID-19 infection but also at higher risks of suffering severe, and possibly fatal, outcomes from the infection. | 2020-06-26 |
| 32583169 | In this series, six patients younger than 55 years of age with diagnosis of stroke and a confirmed diagnosis of COVID-19 were evaluated for symptoms, lab data, imaging findings, and outcomes from March 2020 to the end of April 2020 from all stroke cases in a tertiary academic hospital. | 2020-06-27 |
| 32583171 | PCR-based viral RNA to confirm the diagnosis of SARS-CoV-2 infection has a sensitivity of around 70%. | 2020-06-27 |
| 32583183 | Olfactory loss could be one of those early symptoms which might help in the diagnosis of COVID-19 patients. | 2020-06-27 |
| 32583729 | In this work we have employed In Silico techniques such as immunoinformatics tools which permit the identification of potential immunogenic regions on the viral surface (spike glycoprotein). | 2020-06-25 |
| 32583765 | Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. | 2020-06-25 |
| 32583852 | The use of all major SARS-CoV-2 antigens was demonstrated to have diagnostic value. | 2020-06-25 |
| 32584236 | In this narrative review, the Turkish Thoracic Society Early Career Taskforce members aimed to provide a summary on recent literature regarding epidemiology, clinical findings, diagnosis, treatment, prevention, and control of COVID-19. | 2020-06-26 |
| 32584377 | Histopathologic analysis of skin biopsy specimens (22 patients) confirmed the diagnosis of chilblains and showed occasional lymphocytic or microthrombotic phenomena. | 2020-06-25 |
| 32584397 | Among 32 referred patients, 20 children and adolescents with new-onset inflammatory lesions did not have a diagnosis. […] The clinical, histologic, and laboratory test results were compatible with a diagnosis of perniosis, and no evidence was found to support the implication of SARS-CoV-2 infection. | 2020-06-25 |
| 32584464 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus and resulting COVID-19 pandemic present important diagnostic challenges. […] Several diagnostic strategies are available to identify current infection, rule out infection, identify people in need of care escalation, or to test for past infection and immune response. […] To assess the diagnostic accuracy of antibody tests to determine if a person presenting in the community or in primary or secondary care has SARS-CoV-2 infection, or has previously had SARS-CoV-2 infection, and the accuracy of antibody tests for use in seroprevalence surveys. […] We included all reference standards to define the presence or absence of SARS-CoV-2 (including reverse transcription polymerase chain reaction tests (RT-PCR) and clinical diagnostic criteria). […] The sensitivity of antibody tests is too low in the first week since symptom onset to have a primary role for the diagnosis of COVID-19, but they may still have a role complementing other testing in individuals presenting later, when RT-PCR tests are negative, or are not done. | 2020-06-26 |
| 32584604 | CT is more sensitive to detect early parenchymal lung abnormalities and disease progression, and can provide an alternative diagnosis. | 2020-06-25 |
| 32584766 | The characteristic radiological findings can be exploited in the diagnosis of COVID-19, and radiologists should have knowledge of the usual manifestations of COVID-19, as they may play a role in early detection and diagnosis of the disease. | 2020-06-25 |
| 32585617 | We describe our experience in seven cases of patients with multiple sclerosis who have been affected by SARS-COV-2 (with a clinical/serological diagnosis or PCR diagnosis) and who were being treated with anti-CD20+ monoclonal antibodies. | 2020-06-27 |
| 32585619 | The rapid diagnosis of Coronavirus Disease 2019 (COVID-19) patients is essential to reduce the disease spread. | 2020-06-27 |
| 32585723 | The latest Royal College of Obstetricians and Gynaecologists guidance for diagnosis of gestational diabetes mellitus (GDM) recommends avoiding the ‘gold standard’ 2-h oral glucose tolerance test (OGTT) for the duration of the COVID-19 pandemic [1]. […] To avoid prolonged waiting in large groups the suggested alternative diagnostic pathway involves four simpler tests, in women at greater risk of developing GDM according to the National Institute for Health and Care Excellence (NICE) checklist. | 2020-06-25 |
| 32586214 | The growing awareness and mechanistic understanding of the prothrombotic state of COVID-19 patients is driving efforts to more stringent diagnostic screening for thrombotic compli¬cations and to the early institution of antithrombotic drugs, for both the prevention and therapy of thrombotic complications. […] The shifting paradigm of diagnostic and treatment strategies holds significant promise to reduce the burden of thrombotic complications and ultimately improve the prognosis for patients with COVID-19. | 2020-06-26 |
| 32586394 | Positive SARS-CoV-2 diagnostic (on pharyngeal swab of deep airways material) 3. | 2020-06-28 |
| 32586670 | In conclusion, thrombocyte count is key in both diagnosis and prognosis. […] And although lymphocyte, D-dimer and CRP levels did not demonstrate diagnostic value, all indicate severity of COVID-19. | 2020-06-28 |
| 32586885 | The epidemiology, immunology of these viral infections and their interactions with TB are discussed with implications on diagnosis, treatment and prevention of airborne infections (infection control, viral containment and workplace safety). | 2020-06-26 |
| 32586958 | Herein, we detail the clinicoradiologic work-up and diagnosis, clinical course, and multidisciplinary medical management of this patient with COVID-19. | 2020-06-26 |
| 32586968 | Data pertaining to diagnosis of COVID-19 infection, patient demographics, and risk factors were collected. | 2020-06-26 |
| 32587152 | Suspension of oncology services will have major implications on cancer care due to delayed diagnosis and treatment leading to irreversible adverse consequences. | 2020-06-26 |
| 32587157 | Some major barriers to diagnosis and management are compromised detailed examination, no measurement of the visual acuity or intraocular pressure and a retinal evaluation not being feasible. | 2020-06-26 |
| 32587169 | Computer vision syndrome was the commonest diagnosis (25.9%) followed by conjunctivitis (17.7%) and refractive error (17.7%). […] About 40% required physical examination, mostly due to uncertain diagnosis (22%) or inadequate response to prescribed treatment (19%). […] WhatsApp was the preferred communication modality, computer vision syndrome was the most frequent tentative diagnosis and approximately 60% did not require in-person physical examination. | 2020-06-26 |
| 32587902 | Background: This systematic review had three aims: i) to determine the frequency of anosmia (or other smell disorders) and dysgeusia (or other taste disorders) in COVID-19 patients; ii) to determine whether anosmia or dysgeusia are independently associated with COVID-19 diagnosis; and iii) to determine whether anosmia or dysgeusia are prognostic factors for impaired outcomes among COVID-19 patients. Methods: On April 20 th, 2020, we search MEDLINE, Embase, Global Health, Scopus, Web of Science and MedXriv. […] Two reports studied whether smell and taste disorders were independently associated with COVID-19 diagnosis. […] People who reported loss of smell and taste had six-fold higher odds of being COVID-19 positive; similarly, anosmia and ageusia were associated with 10-fold higher odds of COVID-19 diagnosis. Conclusions: The frequency of smell and taste disorders is as high as other symptoms, thus, at least anosmia for which the definition was more consistent, could be included in lists of COVID-19 symptoms. […] Although there is promising evidence, it is premature to conclude that smell and taste disorders are strongly associated with COVID-19 diagnosis. Registration: PROSPERO CRD42020181308. | 2020-06-27 |
| 32588051 | We described characteristics of these cases, compared the diagnostic accuracy and features of blood testing, computed tomography (CT) scans and X-rays, and analysed SARS-CoV-2 transmission sources and patients’ occupations in Henan province. […] The mean time from illness onset to diagnosis was 5.6 days. […] Lymphocyte percentage was a sign of severe COVID-19 in general but was not a good diagnostic index. […] Longer time from illness onset to diagnosis was associated with higher COVID-19 severity, older age, higher likelihood of having coexisting cardiovascular diseases including hypertension, and being male. | 2020-06-26 |
| 32588061 | Diagnostic and therapeutic implications of this are also discussed. | 2020-06-26 |
| 32588200 | AI-driven tools are used to identify Coronavirus outbreaks as well as forecast their nature of spread, where imaging techniques are widely used, such as CT scans and chest X-rays (CXRs). | 2020-06-28 |
| 32588277 | Our aim is to display the chest CT findings at first assessment and follow-up through a pictorial essay, to help in the recognition of these features for an accurate diagnosis. | 2020-06-28 |
| 32588367 | It is suggested that determining these neurological symptoms prevents the diagnosis delay and helps to prohibit virus spread. | 2020-06-28 |
| 32588499 | Yet psychological theory and therapeutic techniques can be readily applied to address physical inactivity. […] We present theoretical perspectives and therapy techniques relating to (1) beliefs about physical activity, (2) motivation to be physically active, and (3) the sense of reward achieved through being physically active. […] Psychological theory and techniques to address beliefs, motivation, and reward can be applied to increase physical activity during COVID-19. | 2020-06-26 |
| 32588565 | When dealing with the highly contagious viral disease-related cardiac manifestations, we should carefully apply the diagnostic and therapeutic methods to achieve the best therapeutic results without adding any risk of disease transmission. | 2020-06-26 |
| 32588614 | Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. | 2020-06-26 |
| 32589189 | The study included patients with MS presenting with a confirmed or highly suspected diagnosis of COVID-19 between March 1, 2020, and May 21, 2020. | 2020-06-26 |
| 32589296 | Since then, this disease has rapidly spread across the globe and in March 2020 the World Health Organization (WHO) declared the COVID-19 pandemic.1 Since the outbreak was first announced, our journal has extensively focused on the clinical features, outcomes, diagnosis, immunology, and pathogenesis of COVID-19 and its infectious agent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). | 2020-06-26 |
| 32589448 | The identification of the virus in postmortem tissues is a fundamental step in the definition of its clinical features. Objective To investigate the presence of Sars-CoV-2 in the postmortem with swabs. Design We performed postmortem swabs in 12 autopsy cases of patients with a clinical diagnosis of Sars-CoV-2 related pneumonia. | 2020-06-26 |
| 32589451 | Estimated risks (cumulative incidences) per 10 000 persons and 95% CIs for polymerase chain reaction-confirmed COVID-19 diagnosis, hospitalization, intensive care unit (ICU) admission, and death. […] Risk and 95% CIs for COVID-19 diagnosis and hospital admission by use of the NRTIs tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC), tenofovir alafenamide (TAF)/FTC, abacavir (ABC)/lamivudine (3TC), and others were estimated through Poisson regression models. […] The risks for COVID-19 diagnosis and hospitalization were greater in men and persons older than 70 years. […] The corresponding risks for COVID-19 diagnosis were 39.1 (CI, 31.8 to 47.6), 16.9 (CI, 10.5 to 25.9), 28.3 (CI, 21.5 to 36.7), and 29.7 (CI, 22.6 to 38.4), respectively. | 2020-06-26 |
| 32589496 | The ED diagnosis distribution significantly changed during COVID-19 (P = .013), with an 84% decrease in the number of patients hospitalized for diverticular disease (P < .05). Conclusion: During the COVID-19 outbreak, the overall number of patients presenting at the ED with surgical complaints decreased significantly, and there was a higher admissions ratio. | 2020-06-26 |
| 32589687 | Because of limited testing capacity, symptom-based screening may prioritize testing and increase diagnostic accuracy. | 2020-06-26 |
| 32589755 | The change of these indexes in patients with different COVID-19 types could provide reference for the disease severity identification and diagnosis of COVID-19. | 2020-06-26 |
| 32590125 | Neurologic manifestations of the disease are increasingly identified and this will help clinician to improve their diagnostic and therapeutic skills in dealing with COVID-19 patients. […] Electrodiagnostic evaluation in patient revealed demyelinating type polyneuropathy and patient diagnosed as Guillain-Barré syndrome (AIDP type) and treated with IVIG which resulted in favorable response. | 2020-06-28 |
| 32591152 | The COVID-19 pandemic is changing approaches to diagnosis, treatment, and care provision in multiple sclerosis (MS). | 2020-06-27 |
| 32591166 | The current gold standard for etiologic diagnosis is reverse transcription-polymerase chain reaction analysis of respiratory-tract specimens, but the test has a high false-negative rate owing to both nasopharyngeal swab sampling error and viral burden. […] Hence diagnostic imaging has emerged as a fundamental component of current management of COVID-19. […] Currently, high-resolution computed tomography is the main imaging tool for primary diagnosis and evaluation of disease severity in patients. […] Although the number of studies to date is limited, LUS findings have demonstrated high diagnostic sensitivity and accuracy, comparable with those of chest computed tomography scans. […] The goal is to identify characteristic sonographic findings most suited for the diagnosis of COVID-19 pneumonia infections. | 2020-06-27 |
| 32591286 | Clinical signs help guide initial diagnosis, though definitive diagnosis is made using the laboratory technique reverse transcription polymerase chain reaction (RT-PCR). | 2020-06-27 |
| 32591346 | We assessed the merits of these PRM assays using supernatants of virus-infected Vero E6 cells and challenged the assays by analyzing two diagnostic cohorts of 24 (+30) SARS-CoV-2 positive and 28 (+9) negative cases. | 2020-06-27 |
| 32591656 | The authors offer some methods of trying to protect oro-maxillofacial surgeons, using an algorithm of diagnosis and classifying the risk of contamination and the materials required in order to avoid it.Conclusions In conclusion, the authors suggest the use of the algorithm for patient admission during the COVID-19 outbreak. | 2020-06-27 |
| 32591660 | The authors provide information on the COVID-19 pandemic in order to inform front-line dentists.The paper is as essay on the available information relating to:Background to the pandemic• Coronaviruses in general• Pathogenesis• COVID-19• Clinical manifestations• Patient characteristics• Diagnosis• Protocol for managing the disease in the clinical setting• Transmission dynamics• Transmission dynamics in dentistry practice• Infection control• Mouth rinses• Rubber dam isolation• Anti-retraction handpiece• Appropriate disinfectants• Management of medical waste.Conclusions Face-to-face communication and consistent exposure to body fluids such as blood and saliva predispose dental care workers to risk of infection and there is high risk of cross-infection. | 2020-06-27 |
| 32591666 | Study selection The study selected trials, reviews, and in-vitro research assessing the critical aspects of saliva as an easily accessible and early-stage diagnostic source, and also an entry route for 2019-nCoV. […] Studies were not restricted to English language and they were not all full-text papers.Data extraction and synthesis A narrative synthesis of the results was conducted using distinct headings and subheadings, defined by the authors based on relevancy to the consensus about the importance of saliva with reference to 2019-nCoV.Results There was an inherent heterogeneity among the included clinical studies concerning their designs, sampling techniques, and the results about the diagnostic value of saliva. […] According to the comparisons between 2019-nCoV and SARS-CoV, saliva could be considered of diagnostic value via the early detection of viral RNA for both of the viruses. […] Finally, this paper warns about airborne transmission, particularly for close contacts.Conclusions Saliva can be proposed as an easily accessible diagnostic source although further clinical studies are required. | 2020-06-27 |
| 32591667 | The presentation section introduced the signs and symptoms, diagnosis, high risk groups, and complications of COVID-19. | 2020-06-27 |
| 32592498 | In reference to the comments by Dramé M., et al., 2020, that question the possibility of whether the reverse-transcriptase-polymerase-chain-reaction (RT-PCR) for viral load should be considered a gold standard in the diagnosis of Covid-19. | 2020-06-27 |
| 32592502 | The detection of antibodies produced during the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become an important laboratory method for the diagnosis of COVID-19. […] In this study, retrospective analysis was used to explore the dynamic changes of serum IgM and IgG antibody and factors affecting diagnostic efficacy, so as to provide a theoretical basis for clinical diagnosis and treatment. | 2020-06-27 |
| 32592709 | Chest computed tomography (CT) may be used for the diagnosis of Corona virus disease 2019 (COVID-19), but clear scientific evidence is lacking. […] More high-quality research is necessary to establish diagnostic CT criteria for COVID-19. | 2020-06-27 |
| 32592724 | Although the use of ready-made reaction mixes can enable more rapid PCR-based diagnosis of COVID-19, the need to transport and store these mixes at low temperatures presents challenges to already overburdened logistics networks. […] The uptake of this approach will ease logistical challenges faced by transport networks and make more cold storage space available at diagnosis and hospital laboratories. | 2020-06-27 |
| 32592842 | Instead we could see a diverse COVID-19 pandemic profile in the WPR, and several creative diagnostic and therapeutic measures undertaken. | 2020-06-27 |
| 32592911 | The corona virus pandemic has ignited a proliferation of research aimed at prevention of spread, early diagnosis and treatment. | 2020-06-27 |
| 32593418 | Clinical and diagnostic details of cardiovascular involvement in these patients are mostly limited to biochemical markers. | 2020-06-29 |
| 32593741 | To face the current COVID-19 pandemic, diagnostic tools are essential. […] It is recommended to use real-time RT-PCR for RNA viruses in order (a) to perform a rapid and accurate diagnostic, (b) to guide patient care and management and (c) to guide epidemiological strategies. […] Further studies are warranted to define the role of serological diagnosis and a possible correlation between serological response and prognosis. […] The aim was to guide clinical microbiologists in the use of these diagnostic tests and clinicians in the interpretation of their results. […] A search of literature was performed through PubMed and Google Scholar using the keywords SARS-CoV-2, SARS-CoV-2 molecular diagnosis, SARS-CoV-2 immune response, SARS-CoV-2 serology/antibody testing, coronavirus diagnosis. […] The present review discusses performances, limitations and use of current and future diagnostic tests for SARS-CoV-2. […] Real-time RT-PCR remains the reference method for diagnosis of SARS-CoV-2 infection. | 2020-06-29 |
| 32593807 | It has been stalemated, in part, by advocates, who argue for personal autonomy and freedom rather than involuntary diagnosis and treatment over the life of these people. | 2020-06-29 |
| 32593867 | Although this is a retrospective analysis, results suggest that early diagnosis, early isolation and early treatment of COVID-19 patients, with at least 3 days of HCQ-AZ lead to a significantly better clinical outcome and a faster viral load reduction than other treatments. | 2020-06-29 |
| 32593875 | SARS-CoV-2 has caused COVID-19 pandemic globally in the beginning of 2020, and qualitative real-time RT-PCR has become the gold standard in diagnosis. | 2020-06-29 |
| 32594170 | We used droplet digital polymerase chain reaction (ddPCR) to demonstrate that human DNA levels, a stable molecular marker of sampling quality, were significantly lower in samples from 40 confirmed or suspected COVID-19 cases that yielded negative diagnostic test results (ie, suspected false-negative test results) compared with a representative pool of 87 specimens submitted for COVID-19 testing. | 2020-06-29 |
| 32594281 | Provide detailed online diagnosis, online treatment recommendations, and face-to-face consultation suggestions. | 2020-06-29 |
| 32594577 | The detection of serum antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is emerging as a new tool for the coronavirus disease 2019 (COVID-19) diagnosis. | 2020-06-29 |
| 32594937 | Quantitative studies that recruited people with confirmed COVID-19 diagnosis were included. | 2020-06-30 |
| 32595349 | In this review, we present the current scenario and status of epidemiology, diagnosis, treatment, vaccine development for COVID-19, and its impact on the socio-economic structure. | 2020-06-30 |
| 32595353 | With its highly contagious characteristic and long incubation time, confinement of SARS-CoV-2 requires drastic lock-down measures to be taken and therefore early diagnosis is crucial. | 2020-06-30 |
| 32595580 | The baseline, job before diagnosis, presumed infection environment, use of protective equipment, and psychological status before and after diagnosis were collected and analyzed. […] A total of 77.78% of the staff experienced psychological stress or emotional changes after diagnosis, which were mainly caused by family health and disease related issues. | 2020-06-30 |
| 32595654 | Therefore, there is an urgent need to develop a framework for the rapid identification of novel targets for diagnostic and therapeutic interventions. | 2020-06-30 |
| 32595762 | In this review, we summarise recent findings on the epidemiology of GI tract involvement, potential mechanisms of faecal-oral transmission, GI and liver manifestation, pathological/histological features in patients with COVID-19 and the diagnosis, management of patients with pre-existing GI and liver diseases as well as precautions for preventing SARS-CoV-2 infection during GI endoscopy procedures. | 2020-06-30 |
| 32596069 | This poses an ongoing challenge in the diagnostic and therapeutic approach for managing these patients. | 2020-06-30 |
| 32596073 | We present the diagnostic and therapeutic approach to this case. | 2020-06-30 |
| 32596083 | We explore several possible reasons for serially negative SARS-CoV-2 testing and other potential avenues of diagnosis. | 2020-06-30 |
| 32596428 | In the bioinformatics area, one of the crucial points is the analysis of the virus nucleotide sequences using approaches such as data stream techniques and algorithms. | 2020-06-30 |
| 32596642 | However, the closed-ward environment and extreme shortage of onsite mental health workers have limited the use of traditional face-to-face diagnosis and psychological interventions. | 2020-06-30 |
| 32597047 | As a result, more conservative approaches might be preferred in children for the diagnostic, clinical, and even therapeutic applications. | 2020-06-30 |
| 32597048 | COVID-19 diagnosis and infection severity were identified from reimbursement data using diagnosis codes and on the basis of respiratory support use, respectively. | 2020-06-30 |
| 32597076 | So far, National Health Commission of the People’s Republic of China has issued seven trial versions of the “Guidelines for the Diagnosis and Treatment of COVID-19”. […] This paper reports a computer-aided intelligent analysis method based on machine learning, which can automatically analyze the similarities and differences of different treatment plans, present the focus of the new version to doctors, reduce the difficulty in interpreting the “diagnosis and treatment plan” for the professional, and help the general public better understand the professional knowledge of medicine. […] It enables the computer interpretation of “diagnosis and treatment plan” automatically and intelligently. | 2020-06-30 |
| 32597101 | All the staff involved in the project of a Covid-free hospital should be subjected to a diagnostic swab for COVID-19 before the beginning of healthcare activity and then periodically in order to avoid the risk of contamination of patients during the process of care. | 2020-06-30 |
| 32597389 | As COVID-19 cases continue to increase globally, fragile health systems already facing challenges with health system infrastructure, SARS-CoV-2 diagnostic capacity, and patient isolation capabilities may be left with few options to effectively care for acutely ill patients. | 2020-06-30 |
| 32598303 | Detection of SARS-CoV-2 in respiratory samples by using PCR is the standard laboratory diagnostic tool. […] Our aim was to perform a limited evaluation of the diagnostic performance and user-friendliness of eleven rapid tests for detection of antibodies against SARS-CoV-2. | 2020-06-30 |
| 32598306 | Laboratories should consider reporting quantitative viral load data in the molecular diagnosis of SARS-CoV-2 infection. | 2020-06-30 |
| 32598557 | The median interval from diagnosis to providing semen samples was 32 days, when total sperm counts, total motile sperm counts, and sperm morphology of the patients were within normal ranges. | 2020-06-30 |
| 32598911 | Women with a current or previous diagnosis of ovarian cancer completed an online survey focusing on treatment interruptions and quality of life. | 2020-06-30 |
| 32598953 | This article reviewed the clinical use, mechanism and efficacy of the clinically approved drugs recommended in the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (DTPNCP) released by National Health Commission of P.R.China, and the novel therapeutic agents now undergoing clinical trials approved by China National Medical Products Administration (NMPA) to evaluate experimental treatment for COVID-19. | 2020-06-30 |
| 32599100 | This study used publicly available data to examine gender, age, source of infection, date returned from Hubei, date of disease onset, date of first medical visit, date of final diagnosis, and date of recovery of COVID-19 cases. […] The mean periods from disease onset to first medical visit, first visit to final diagnosis, and final diagnosis to recovery were 4.44, 3.18, and 13.42 days, respectively. | 2020-06-30 |
| 32599159 | More attention should be paid to investigation of household contact history in the diagnosis of COVID-19 in young children. | 2020-06-30 |
| 32599282 | Rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for the diagnosis of coronavirus disease 2019 (COVID-19) and preventing the spread of the virus. | 2020-06-30 |
| 32599338 | In this paper, with the aim of providing a fully automatic and faster diagnosis, we propose the adoption of deep learning for COVID-19 detection from X-rays. | 2020-06-30 |
| 32599813 | Diagnosis of CAPA remains challenging, mainly because bronchoalveolar lavage fluid galactomannan testing and culture, which represent the most sensitive diagnostic tests for aspergillosis in the ICU, are hindered by the fact that bronchoscopies are rarely performed in COVID-19 patients due to the risk of disease transmission. | 2020-07-01 |
| 32599968 | But, especially in asymptomatic or pre-symptomatic COVID-19 patients, skin lesions can lead to the diagnosis of COVID-19. […] Even if there were no COVID-19 diagnosis, skin findings should be evaluated carrefully in this pandemic period. | 2020-07-01 |
| 32599972 | The patients with those factors should be evaluated more carefully for diagnostic procedures, such as thorax CT. | 2020-07-01 |
| 32600378 | The patients will be randomly divided into three groups, two of them will perform a home exercise program (breathing exercises or non-specific exercises for muscle toning) and the third group will perform sedentary activities, using mental activation techniques, and will act as a sham group. | 2020-07-01 |
| 32600464 | All these cases share a significant diagnostic delay caused by the parents’ reluctance to seek medical attention, seen as a potential risk factor for COVID-19 contagion. | 2020-07-01 |
| 32600800 | Respecting contra-indications and judicial use of safety techniques and norms are essential. | 2020-07-01 |
| 32600935 | Atypical presentations are more frequent in the elderly and can delay the diagnosis. | 2020-07-01 |
| 32600945 | One-third of respondents had a prior diagnosis of an anxiety disorder, and 11% reported taking anxiolytic medications; over one-quarter had a prior diagnosis of a depressive disorder and 11% reported taking antidepressant medications. | 2020-07-01 |
| 32600991 | Of the total population, 447 979 inhabitants, 965 patients (0.22%) were diagnosed with COVID-19 infection, and 210 (21.8%) were under ACEI or ARB treatment at the time of diagnosis. | 2020-07-01 |
| 32601019 | From practice of prophylactic measures to availability of personal protective equipment, from access to diagnostic tests to treatment resources, there are many facets and distinct disease processes of a virus that, among many things, serves to expose and highlight our global disparities. | 2020-07-01 |
| 32601037 | In this scenario, the Oncological Institutes are forced to make a rigorous selection of patients to undergo endoscopic examinations and treatments, according to lists of exceptional priorities, in order to guarantee cancer patients and subjects at high risk of developing digestive tumors, a preferential diagnostic and therapeutic process, protected from contagion risks. | 2020-07-01 |
| 32601278 | However, inconsistency and ambiguity in instructions show a lack of definitive knowledge on best spray use techniques. […] In this study, we have identified a new usage strategy for nasal sprays available over-the-counter, that registers an average 8-fold improvement in topical delivery of drugs at diseased sites, when compared to prevalent spray techniques. | 2020-07-01 |
| 32601725 | The FAHZU, as the earliest designated hospital, accomplished the transformation from general hospital to infectious disease hospital under the guiding ideology of centralized patients, centralized experts, centralized resources, and centralized treatment with measures to transfer the Zhijiang campus hospitalized patients quickly, complete the space layout, create diagnosis and treatment space, streamline logistics, and transform logistics facilities within 48 h. […] The successful cases of FAHZU provided a valuable experience for large medical institutions on how to address public health emergencies and how to carry out diagnosis and treatment and streamline the layout and related facilities in emergency reconstruction. | 2020-07-01 |
| 32601787 | The risk of contamination is high during dental radiography if proper disinfection techniques are not applied. | 2020-07-01 |
| 32602046 | In this study, we successfully established long term cultures of normal human kidney proximal tubule epithelial cells (KPTECs) in 2D and 3D culture systems using conditional reprogramming (CR) and organoids techniques. | 2020-07-01 |
| 32602300 | This research focuses on the application of techniques for modelling and geovisualization of epidemic data with the aim of simple and fast communication of analytical results via geoportal. | 2020-07-01 |
| 32602679 | HRCT chest in COVID-19 patients had a major diagnostic and prognostic importance as positive CT findings were more prominent in symptomatic patients and co-morbid patients. | 2020-07-01 |
| 32602929 | This column focuses on the neurobiological explanations for anxiety, complications to pre-existing psychiatric disorders, sub diagnostic states of stress and anxiety generally and with health care providers, and pharmacological and nonpharmacological ways of addressing this anxiety. | 2020-07-01 |
| 32603572 | Introduction This case series describes the diagnosis of the first case of community transmission of SARS-CoV-2 in the Republic of Ireland. […] This diagnosis had far-reaching implications for the SARS-CoV-2 pandemic within Ireland. | 2020-07-01 |
| 32603801 | To validate the diagnostic accuracy of a Euroimmun SARS-CoV-2 IgG and IgA immunoassay for COVID-19. […] Diagnostic accuracy of the immunoassay was assessed against a whole spike protein-based recombinant immunofluorescence assay (rIFA) by receiver operating characteristic (ROC) analyses. […] ROC curve analyses indicated that IgG and IgA had high diagnostic accuracies with AUCs of 0.990 (95% Confidence Interval [95%CI]: 0.983-0.996) and 0.978 (95%CI: 0.967-0.989), respectively. […] The Euroimmun assay displays a nearly optimal diagnostic accuracy using IgG against SARS-CoV-2 in patient samples, with no obvious gains from IgA serology. | 2020-07-01 |
| 32604085 | The purpose of this study was to evaluate protocol settings, associated radiation exposure, image quality and diagnostic performance of a low-dose CT protocol in a university hospital setting. […] Images were evaluated with regard to protocol parameters, image quality, radiation exposure and diagnostic accuracy. […] We presented a robust imaging procedure with a chest CT protocol for confident diagnosis of COVID-19. […] Even for an overweight patient cohort, an associated radiation exposure of only 1.3 ± 0.4 mSv was achieved with sufficient diagnostic quality to exclude COVID-19. | 2020-07-01 |
| 32604138 | We analyzed each of the cases to extract information including demographics, medical comorbidities, clinical presentation, and illness course after COVID-19 diagnosis. | 2020-07-01 |
| 32604247 | We also had extensive discussions with colleagues who are developing telehealth techniques relevant to neuro-ophthalmology. | 2020-07-01 |
| 32604457 | While physical examination (identification of abnormalities) and diagnostic tests (identification of pathogens) can be useful for detecting illnesses and asymptomatic infections as well as assessing the general health condition of a patient, including his immune system. | 2020-07-01 |
| 32604585 | The goal of this paper was to apply unsupervised machine learning techniques towards the discovery of latent clusters in COVID-19 patients. | 2020-07-02 |
| 32604588 | A timely and accurate diagnosis of COVID-19 is the cornerstone for the prompt management of the patients. […] The aim of the present study was to evaluate the performance of an automated machine learning algorithm in the diagnosis of Covid-19 pneumonia using chest CT scans. […] Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC), sensitivity, and positive predictive value. | 2020-07-02 |
| 32604591 | Application of topic modeling techniques to streaming social media Twitter provides the foundation for research team insights regarding information and future virtual based intervention and social media based health disparity research for COVID-19. | 2020-07-02 |
| 32604593 | The aim of our study is to propose a remote patient monitoring solution through a smart phone application (Smart Patient) collecting health data to support diagnosis, monitoring and predicting poor outcome in asymptomatic/mild cases of COVID-19, including signs and symptoms, risk factors, comorbidities, medications and vital signs such as body temperature, respiratory rate, heart rate and oxygen saturation. | 2020-07-02 |
| 32604724 | We focus on shared genomic features of the betacoronaviruses and the application of genomic information to phylogenetic analysis, molecular epidemiology and the design of diagnostic systems, potential drugs and vaccine candidates. | 2020-07-02 |
| 32604919 | This review summarizes and compares the available POCD and those currently under development, including quantitative reverse transcription PCR (RT-qPCR), serology immunoassays (SIAs) and protein microarray method (PMM) designed for standard and rapid COVID-19 diagnosis. | 2020-07-02 |
| 32605097 | Lastly, it provides communication techniques that should be implemented, targeting each citizen segment for a long-term COVID-19 free country. | 2020-07-02 |
| 32605192 | Consequently, the scientific community is working hard to gain useful information about the history of this virus, its transmission, diagnosis, clinical features, radiological findings, research and development of candidate therapeutics as well as vaccines. […] This review aims to analyze the diagnostic techniques used to ascertain the COVID-19 infection, critically reviewing positive points and criticism for forensic implications, obviously including autopsy. […] Analyzing the diagnostic methods, to date, virus nucleic acid RT-PCR represents the standard method used to ascertain the COVID-19 infection in living subjects and corpses, even if this technique has several criticisms: mainly, the staff should be highly specialized, working in high-throughput settings, able to handle high workloads and aware of health risks and the importance of the results. […] Nevertheless, serological tests present problems; the WHO recommends the use of these new point-of-care immunodiagnostic tests only in research settings. […] In light of this scenario, in this review, we suggest a flow chart for the pathologist called on to ascertain the cause of death of a subject with historical and clinical findings of COVID-19 status or without any anamnestic, diagnostic, or exposure information. […] Indeed, the literature data confirmed the analytical vulnerabilities of the kits used for laboratory diagnosis of COVID-19, particularly during postmortem examinations. | 2020-07-02 |
| 32605194 | In this review, we discuss the noteworthy advancements, focusing on the etiological viral agent, comparative genomic analysis, population susceptibility, disease epidemiology and diagnosis, animal reservoirs, laboratory animal models, disease transmission, therapeutics, vaccine challenges, and disease mitigation measures. | 2020-07-02 |
| 32605363 | The SARS-CoV-2 pandemic has created an unprecedented need for rapid diagnostic testing to enable the efficient treatment and mitigation of COVID-19. […] The primary diagnostic tool currently employed is reverse transcription polymerase chain reaction (RT-PCR), which can have good sensitivity and excellent specificity. […] Lateral flow assays (LFAs) represent a class of diagnostic that, if sufficiently clinically sensitive, may fill many of the gaps in the current RT-PCR testing regime, especially in low- and middle-income countries (LMICs). […] To date, many serology LFAs have been developed, though none meet the performance requirements necessary for diagnostic use cases, primarily due to the relatively long delay between infection and seroconversion. | 2020-07-02 |
| 32605422 | The study started 2 weeks after the first diagnosis of COVID-19 in Turkey and was carried out between March 23 and April 3, 2020. | 2020-07-02 |
| 32605577 | The need for timely establishment of a complete diagnostic protocol of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is demanded worldwide. […] Our results enhance the recent knowledge on this emerging infectious disease and offer suggestions for a more complete diagnostic strategy. | 2020-07-02 |
| 32605920 | Two deaths occurred in care homes where a diagnosis of COVID-19 allowed the health protection team to provide support in that ‘closed setting’ to reduce the risks of onward transmission. | 2020-07-02 |
| 32606285 | This case highlights the importance of awareness of rare cardiac manifestations of COVID-19 in the form of acute myopericarditis and cardiac tamponade and their early diagnosis and management. | 2020-07-02 |
| 32607246 | The only approved diagnostic test to accompany radiographic evaluation is reverse transcription PCR. […] However, the applicability of this test in diagnosis and surveillance is challenged by a global shortage of reagents and the lack of well-equipped laboratories with specialized staff in several low- and middle-income countries. […] Loop-mediated isothermal amplification and CRISPR-based diagnostic assays have developed and expected to play a role however, their accuracy is still inferior to the recommended PCR approach. […] The need for the development of accurate and rapid diagnostic assays became apparent. […] Immunodiagnostic tests and other molecular approaches were developed and tested. […] Fortunately, a number of serological tests have been granted authorization for use under the emergency situation by the US FDA for the diagnosis of SARS-CoV-2. | 2020-07-02 |
| 32607304 | A real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay confirmed a diagnosis of COVID-19 infection, resulting in the patient’s admission to the airborne isolation unit for clinical observation. | 2020-07-02 |
| 32607332 | The diagnostic criteria, clinical classification, and discharge standard related to COVID-19 were in line with the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 7) released by National Health Commission and National Administration of Traditional Chinese Medicine. […] The mean time from onset of symptoms to the first physician visit was 3.38 ± 2.98 (95%CI: 2.58-9.18) d, with a median of 2 (IQR: 1-5) d, and the mean time from hospital admission to confirmed diagnosis was 2.29 ± 2.11 (95%CI: 1.18-6.42) d, with a median of 2 (IQR: 1-3) d. | 2020-07-02 |
| 32607393 | Plasmin is another possible candidate both in diagnosis and treatment areas. | 2020-07-02 |
| 32607405 | A combination of purposive and snowball techniques helped to select the respondents via Whatsapp from more than ten universities in Indonesia. | 2020-07-02 |
| 32607454 | We describe a patient suffering from Covid19-related acute respiratory distress syndrome (ARDS), highlighting the diagnostic role of the EEG in ICU. | 2020-07-02 |
| 32607499 | Early and accurate diagnosis of COVID-19 is thus critical to curbing its spread and improving health outcomes. […] Other techniques, such as recombinase polymerase amplification (RPA), loop-mediated isothermal amplification (LAMP), clustered regularly interspaced short palindromic repeats (CRISPR), and microfluidics, have allowed better disease diagnosis. | 2020-07-02 |
| 32607634 | To develop a predictive model and scoring system to enhance the diagnostic efficiency for coronavirus disease 2019 (COVID-19). […] • Prediction of RT-PCR positivity is crucial for fast diagnosis of patients suspected of having coronavirus disease 2019 (COVID-19). […] • A predictive model and scoring system combining both clinical and CT features were herein developed to enable high diagnostic efficiency for COVID-19. | 2020-07-02 |
| 32607704 | Diagnostic catheterisations, coronary and structural interventions, as well as the incidence and delay to reperfusion therapy of myocardial infarction (STEMI), were recorded. […] There was a significant decrease in the number of diagnostic procedures (-65.2%), coronary interventions (-59.4%), structural therapeutics (-86.1%) and STEMI care (-51.2%). […] Healthcare providers should encourage patients with suspected symptoms of STEMI to call for emergency care to ensure rapid diagnosis and timely reperfusion treatment. | 2020-07-02 |
| 32609142 | to describe the most frequent signs and symptoms of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). this is a narrative literature review carried out in April 2020; the search was performed on electronic databases and complemented with a manual review of the references of the selected papers and Brazilian Ministry of Health publications. the spectrum of clinical disease was wide; fever, coughing and dyspnea were the most frequent signs/symptoms, however, they may not be present, thus hindering case definition; gastrointestinal symptoms and loss of taste or smell have been reported among mild cases; dyspnea was frequent among severe and fatal cases. considering the scarcity of diagnostic tests and the diversity of symptoms, health services should use a sensitive case definition, in order to adopt appropriate surveillance, prevention and treatment actions. | 2020-07-02 |
| 32609144 | In this review, we discuss some favorable aspects and difficulties associated with virtual teaching and learning, searching for available tools and techniques as well as new perspectives. | 2020-07-02 |
| 32609253 | to perform a situational diagnosis of the behavior of health professionals concerning hand hygiene practices in highly-complex sectors. this quantitative and retrospective study was based on reports (2016 and 2017) of Adult and Pediatric ICUs of a Federal hospital in Rio de Janeiro. one thousand two hundred fifty-eight opportunities for hand hygiene were analysed. […] The moment “after contact with the patient” presented 4.5275 times the chance in relation “before contact with the patient”. in front of hand hygiene recommendations to control COVID-19, diagnostic assessment and previous analysis of the behavior of professionals proved to be positive. | 2020-07-02 |
| 32609256 | The diagnosis of COVID-19 is based on the clinical and epidemiological history of the patient. […] However, the gold standard for COVID-19 diagnosis is the viral detection through the amplification of nucleic acids. […] Here we comment on RT-PCR and describe alternative tests developed for the diagnosis of COVID-19. | 2020-07-02 |
| 32609284 | Data were analyzed and synthesized in the form of a narrative. the final sample was composed of 24 records, the content of which was synthesized in these conceptual categories: clinical manifestations, diagnosis, treatment, working pregnant women, vaccine development, complications, prenatal care, vertical transmission, and placental transmissibility. | 2020-07-02 |
| 32609310 | Efforts to track the severity and public health impact of coronavirus disease 2019 (COVID-19) in the United States have been hampered by state-level differences in diagnostic test availability, differing strategies for prioritization of individuals for testing, and delays between testing and reporting. […] In several states, these deaths occurred before increases in the availability of COVID-19 diagnostic tests and were not counted in official COVID-19 death records. | 2020-07-02 |
| 32609640 | The laboratory diagnosis of SARS-CoV-2 infection has relied on nucleic acid testing; however, it has some limitations, such as low throughput and high rates of false negatives. | 2020-07-02 |
| 32609971 | Background: Point-of-care bedside lung ultrasound is a diagnostic adjunct in the management of respiratory diseases. […] Conclusions: Trained clinicians, who are familiar with point-of-care lung ultrasonography, may consider point-of-care bedside ultrasound as an important adjunct to history and physical examination for the diagnosis and management of COVID-19 when advanced imaging is not available because of logistical reasons or infectious control. […] Background: Point-of-care bedside lung ultrasound is a diagnostic adjunct in the management of respiratory diseases. […] Conclusions: Trained clinicians, who are familiar with point-of-care lung ultrasonography, may consider point-of-care bedside ultrasound as an important adjunct to history and physical examination for the diagnosis and management of COVID-19 when advanced imaging is not available because of logistical reasons or infectious control. | 2020-07-02 |
| 32610270 | Interventional and diagnostic procedures represented 27% (n = 14) and 21% (n = 11) of cases, respectively. | 2020-07-02 |
| 32610364 | In the present study, a total of 23,593 patient samples were evaluated by a laboratory from the Mexican Institute of Epidemiological Diagnosis and Reference. […] Patients who tested positive for COVID-19 had a higher proportion of obesity (17.4%), diabetes (14.5%), and hypertension (18.9%) compared with those without a confirmed diagnosis. | 2020-07-02 |
| 32610873 | Majority of COVID-19 positive patients (nearly three-fourth) were asymptomatic (mostly in young age range) at the time of diagnosis, which poses a major challenge for health care workers. | 2020-07-03 |
| 32611226 | Fifty-six young adults completed two naturalistic eHealth search tasks: fact-finding (eHealth Fact) and symptom-diagnosis (eHealth Search). […] Shorter eHealth symptom-diagnosis search time was related to better executive functions, while better eHealth symptom-diagnosis search accuracy was related to better episodic and prospective memory. | 2020-07-03 |
| 32611362 | Intravascular ultrasound (IVUS) was performed and the diagnosis of coronary artery aneurysm was further confirmed. […] Coronary artery aneurysm is a potential reason of infarction, CAG and IVUS are valuable tools in diagnosis in such cases, during the outbreak of coronavirus disease 2019 (COVID-19), home isolation and activity reduction can lead to hypercoagulability, and activities at home should be increased in the high-risk patients. | 2020-07-03 |
| 32611558 | To determine the diagnostic accuracy of serological tests for coronavirus disease-2019 (covid-19). […] Risk of bias was assessed using quality assessment of diagnostic accuracy studies 2 (QUADAS-2). […] Higher quality clinical studies assessing the diagnostic accuracy of serological tests for covid-19 are urgently needed. | 2020-07-03 |
| 32611796 | In contrast, SARS-CoV-2 can be detected in the stool of some patients for greater than 4 weeks, suggesting that stool may hold utility as an additional source for diagnosis. […] Our results demonstrate acceptable agreement between two commercially available molecular assays and support the use of stool PCR to confirm diagnosis when SARS-CoV-2 is undetectable in the upper respiratory tract. | 2020-07-03 |
| 32611911 | At present, reverse transcription-polymerase chain reaction (RT-PCR) from the upper respiratory tract samples is the diagnostic test of choice. | 2020-07-03 |
| 32611915 | The currently available diagnostic tools for the diagnosis of COVID-19 are mainly based on molecular assays. […] Real-time reverse transcription-polymerase chain reaction is the only diagnostic method currently recommended by the World Health Organization for COVID-19. | 2020-07-03 |
| 32612430 | Herein, we aimed to investigate unclear issues related to transmission and pathogenesis of disease as well as accuracy of diagnostic tests and treatment modalities. | 2020-07-03 |
| 32612432 | In this review, we aimed to present the current understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and neonatal periods considering diagnosis, treatment, prognosis, and prevention. | 2020-07-03 |
| 32612615 | Finally, it appears possible to delineate certain major challenges deserving of exhaustive investigation to further understand COVID-19 immunopathogenesis, thus helping to design more effective diagnostic, therapeutic, and prophylactic strategies. | 2020-07-03 |
| 32612749 | In less than six months since its first diagnosis in Wuhan, China, the COVID-19 infectious disease due to the novel coronavirus has infected over 5,000,000 people and claimed over 350,000 lives. | 2020-07-03 |
| 32613004 | A novel strategy is presented for reliable diagnosis and progression prediction of diseases with special attention to COVID-19 pandemic. […] Evidence-based thresholds can be applied to the pathogenicity model and used for diagnosis as well as for early detection of patients in risk of developing the most severe forms of the disease. […] Analysis of patients with differential course of disease can help in detecting biomarkers of diagnostic and prognostic significance. | 2020-07-03 |
| 32613287 | Texture analysis can provide reliable and objective information for differential diagnosis of COVID-19. | 2020-07-03 |
| 32613385 | The main objective of our study is to assess cumulative incidence of pulmonary embolism (PE) in non critically ill COVID-19 patients and to identify its predicting factors associated to the diagnosis of pulmonary embolism. | 2020-07-03 |
| 32613877 | Because of detection of potential false negatives in that cohort, the NAAT results of paired OS and NPS samples from 50 additional recruits with COVID-19 during their recovery stage were used in a second prospective study to compare the diagnostic values of the 2 viral RNA sampling methods. | 2020-07-03 |
| 32613916 | The coronavirus disease 2019 pandemic requires urgent modification to existing head and neck cancer diagnosis and management practices. […] A combined diagnostic and therapeutic surgical approach was undertaken where possible. […] The protocol is applicable across the UK and avoids diagnostic delay. | 2020-07-03 |
| 32613929 | The second is to adapt and adopt current venous thromboembolism diagnostic and treatment guidelines, while relying on the limited available observational reporting of COVID-19 patients to create a comprehensive clinical guideline to treat COVID-19 patients. | 2020-07-03 |
| 32614283 | Many countries and public health bodies utilise ‘syndromic surveillance’ (using real-time, often non-specific symptom/preliminary diagnosis information collected during routine healthcare provision) to supplement public health surveillance programmes. | 2020-07-03 |
| 32614284 | The Romanian Society of Digestive Endoscopy (SRED) and the Romanian Association of Endoscopic Surgery (ARCE) have decided to establish a joint working group to elaborate specific recommendations for organizing the diagnostic and the minimally invasive interventional procedures, in the context of the COVID-19 pandemic. […] The objectives of the SRED and ARCE recommendations target the endoscopic and laparoscopic surgery activities, to support their non discriminatory used for diagnostic or therapeutic purposes, pursuing the demonstrated benefits of these procedures, in safe conditions for patients and medical staff. | 2020-07-03 |
| 32614777 | Purpose was further classified into the following categories: news, general information, self-diagnosis, contact tracing, notices to contacts, notification of close cases, awareness, helplines, monitoring of clinical parameters, recording of symptoms and treatment, and messaging with health care professionals. | 2020-07-03 |
| 32614816 | During April 2-May 7, two additional cases were detected among staff members, and 36 cases were detected among incarcerated and detained persons at the facility; these persons were removed from dormitories and isolated, and the five dormitories that they had resided in before diagnosis were quarantined. | 2020-07-03 |
| 32614854 | To investigate the computed tomography (CT) characteristics and diagnostic value of novel coronavirus pneumonia (NCP or COVID-19) in pregnancy. […] Clinical and chest CT data were collected and clinical symptoms, laboratory indicators, and CT images were analyzed to explore CT characteristics and diagnostic value for COVID-19 during pregnancy. | 2020-07-03 |
| 32615038 | The assay demonstrated high sensitivity and specificity, which is promising for the diagnosis and monitoring as well as control of SARS-CoV-2 worldwide. | 2020-07-03 |
| 32615326 | Neurosensory dysfunction tends to occur in the early stage of COVID-19, and it could be used as a marker for the early diagnosis of COVID-19. | 2020-07-03 |
| 32615621 | This study aimed to determine the rate of preterm birth (PTB) during hospitalization among women diagnosed with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) between 23 and 37 weeks of gestation and whether this rate differs by gestational age at diagnosis of infection. […] Women were stratified into two groups based on gestational age at diagnosis: early preterm (230/7 to 336/7 weeks) versus late preterm (34 to 366/7 weeks). […] Increased maternal age was associated with a lower likelihood of delivery during hospitalization with SARS-CoV-2 infection (aOR: 0.77; 95% CI: 0.58-0.96), while later gestational age at diagnosis of infection was associated with a higher likelihood of delivery during hospitalization (aOR: 2.9; 95% CI: 1.67-8.09). | 2020-07-03 |
| 32615807 | In this case series, chest computed tomography scans and electrocardiograms, along with other diagnostic tests were used to evaluate these individuals. | 2020-07-04 |
| 32615891 | The increase in overall diagnostic yield for urgent EGD in March 2020 versus March 2019 was 7.3% (CI [0.028-0.117], p = .001). […] No statistically significant difference in diagnostic yield for CS between 2019 and 2020 was found.Conclusion: The study showed a statistically significant reduction of urgent EGD and CS performed during the SARS-CoV-2 pandemic, in March 2020, compared to March 2019. […] The diagnostic yield of urgent EGD performed in March 2020 was significantly higher than that of March 2019. […] No statistically significant difference was found in terms of diagnostic yield of urgent CS between March 2020 and March 2019. | 2020-07-04 |
| 32615936 | The early COVID-19 medical literature originated primarily from Asia and focused mainly on clinical features and diagnosis of the disease. | 2020-07-04 |
| 32615987 | All these findings define a histological diagnosis of vasculitis of the gallbladder. | 2020-07-04 |
| 32616067 | Time to diagnosis of positive COVID-19 disease (defined by record of date of symptoms onset and confirmed by laboratory test) RANDOMISATION: Participants will be randomised to either hydroxychloroquine dosed daily with weekly placebo, HCQ dosed weekly with daily placebo, or placebo dosed daily and weekly. | 2020-07-04 |
| 32616405 | The available literature indicates that telemedicine has been implemented successfully in several common clinical scenarios, including the decision-making process following a diagnosis of nonmetastatic PCa, follow-up care of patients with localized PCa after curative treatments, initial diagnosis of hematuria, management diagnosis and follow-up care of uncomplicated urinary stones and uncomplicated UTIs, and initial evaluation, behavioral therapies, and pelvic floor muscle training in UI patients, as well as follow-up care after surgical treatments of stress urinary incontinence or pelvic organ prolapse. | 2020-07-04 |
| 32616498 | The COVID-19 global pandemic has drastically impacted cancer care, posing challenges in treatment and diagnosis. | 2020-07-04 |
| 32616541 | The COVID-19 pandemic has challenged our diagnostic services at a time when many histopathology departments already faced a diminishing workforce and increasing workload. […] This survey indicates an increase in uptake of diagnostic DP during this period, with increased remote access. […] Half of respondents agreed that DP had facilitated maintenance of diagnostic practice. […] We conclude that in our institution, DP has demonstrated current and future potential to increase resilience in diagnostic practice and have highlighted some of the challenges that need to be considered. | 2020-07-04 |
| 32617049 | In this review, we tried to explain how to prevent the negative effects of the COVID-19 pandemic on the diagnosis and treatment of breast cancer patients. | 2020-07-04 |
| 32617050 | All non-urgent procedures, such as elective surgeries and diagnostic interventions, were significantly affected. | 2020-07-04 |
| 32617299 | Abnormalities on chest CT can occur in an early stage of COVID-19, even when RT-PCR assay negative, which may help to early recognition and rapid diagnosis of this disease. | 2020-07-04 |
| 32617403 | Other methods reported to minimize patient discomfort during colonoscopy can be used, in addition to water-aided techniques. | 2020-07-04 |
| 32617690 | A deep learning algorithm consisted of lesion detection, segmentation, and location was trained and validated in 14,435 participants with chest CT images and definite pathogen diagnosis. […] The deep learning algorithm can also assist radiologists make quicker diagnosis (all p < 0.0001) with superior diagnostic performance. […] • The deep learning model improves diagnosis efficiency by shortening processing time. | 2020-07-04 |
| 32617984 | The main purpose of this article is to discuss how orthopedic oncology clinics should be organized during the pandemic and to present the process management scheme for patients requiring orthopedic surgery, including trauma surgery, from diagnosis to treatment, together with our experiences. | 2020-07-04 |
| 32617987 | For diagnosis, the reverse-transcription polymerase chain reaction is the gold standard test for initial diagnosis of COVID-19. […] This review comprehensively summarizes the recent reports available regarding the host-pathogen interaction, morphological and genomic structure of the virus, and the diagnostic techniques as well as the available potential therapeutics against COVID-19. | 2020-07-04 |
| 32618262 | Chest X-ray (CXR) is an essential first-line tool in COVID-19 pneumonia diagnosis and management. | 2020-07-04 |
| 32618463 | In primary care, the fundamental role is the diagnosis of the suspected patients, follow-up mainly by telemedicine (specially telephone calls) to detect warning signs in case of worsening and subsequent referral to the emergency department; as well as explaining home isolation measures. […] In the emergency department, it is included the management of suspicious cases and, if it any risk factor is found, complementary tests are carried out for precise diagnosis and admission assessment; In case of oxygen saturation <95% and poor general condition, valuation is requested for admission to the ICU. | 2020-07-04 |
| 32618600 | Therefore, we provided some suggestions for such patients to manage musculoskeletal pain and techniques that may be performed at home during this period. | 2020-07-04 |
| 32618705 | The prominent perieccrine inflammation is helpful in the diagnosis of COVID-19 infections. […] Patients presenting with suspected COVID-19 infection-induced chilblains who are paucisymptomatic or asymptomatic should be isolated and immediately tested with polymerase chain reaction (PCR) testing (as there is a delay in diagnosis based on the poor sensitivity of the current rapid test). […] We continue to stress the importance of early diagnosis and quarantining to prevent spread to the older and immunocompromised patients. | 2020-07-04 |
| 32618746 | Accurate screening and diagnosis of gestational diabetes are critical to treatment, and in a pandemic scenario like coronavirus disease 2019 needing a simple test that minimises prolonged hospital stay. […] We undertook a meta-analysis on the screening and diagnostic accuracy of the haemoglobin A1c (HbA1c) test in women with and without risk factors for gestational diabetes. […] There is a growing body of evidence on the accuracy of HbA1c as a screening and diagnostic test for GDM. | 2020-07-04 |
| 32618839 | Herein, we aim to describe 2 members of a family affected by COVID-19, presenting with ascending paresthesia with the final diagnosis of Guillain-Barré syndrome. […] Meanwhile the patient was treated with a diagnosis of Guillain-Barré syndrome, his 14-year-old daughter presented with a history of progressive paresthesia and weakness. | 2020-07-04 |
| 32618909 | The diagnosis and management of such patients can be complicated as their clinical characteristics are heterogeneous. […] We also introduce diagnostic criteria, surgical complication management, and follow-up strategies for infected patients. […] These guidelines may be helpful to decrease the infection rate of orthopaedic trauma personnel and to provide diagnosis and treatment therapy for patients with fracture and COVID-19. | 2020-07-04 |
| 32618917 | All patients who were ≥65 years of age, presented to the Emergency Department of the participating hospitals during this period with a diagnosis of proximal femoral fracture, and had a minimum follow-up of 10 days were included in the cohort. | 2020-07-04 |
| 32618968 | Forty-five percent of trauma patients are asymptomatic at the time of SARS-CoV-2 diagnosis. […] Diagnostic tests or criteria, level III, Therapeutic/care management, level IV. | 2020-07-04 |
| 32619398 | These techniques can train the weights of networks on large datasets as well as fine tuning the weights of pre-trained networks on small datasets. […] Due to the small COVID-19 dataset available, the pre-trained neural networks can be used for diagnosis of coronavirus. […] However, these techniques applied on chest CT image is very limited till now. […] Hence, the main aim of this paper to use the pre-trained deep learning architectures as an automated tool to detection and diagnosis of COVID-19 in chest CT. | 2020-07-04 |
| 32619549 | The COVID-19 pandemic is an unprecedented global challenge, and point-of-care diagnostic classifiers are urgently required. | 2020-07-04 |
| 32619595 | The most common diagnostic groups evaluated through video visits were nephrolithiasis (40%), oncology (18%) and andrology (14.3%). | 2020-07-04 |
| 32619841 | The rapid development of global COVID-19 pandemic poses an unprecedented challenge to the safety and quality of laboratory diagnostic testing. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619956 | However, accurate detection is required for SARS-CoV-2 infection diagnosis. […] The IgM-IgG antibody test exhibited a useful adjunct to RT-PCR detection, and improved the accuracy in COVID-19 diagnosis regardless of the severity of illness, which provides an effective complement to the false-negative results from a nucleic acid test for SARS-CoV-2 infection diagnosis after onsets. | 2020-07-04 |
| 32619959 | We sought to compare the sensitivity and specificity of the Aptima SARS-CoV-2 Assay to RTPCR as a means of SARS-CoV-2 detection in a diagnostic setting. | 2020-07-04 |
| 32620027 | All patients discharged from Akershus University Hospital with a diagnosis of transient ischemic attack (TIA) or acute stroke were identified by hospital chart review. | 2020-07-04 |
| 32620311 | A prospective observational study of patients with COVID-19 diagnosis by positive PCR considered high-risk tracked with telemedicine and telemonitoring was conducted in the sanitary area of Lugo between March 17th and April 17th, 2020. | 2020-07-05 |
| 32620590 | Eight significant predictors were identified and used to build a ‘complete’ CBC score with a discriminatory power for COVID-19 diagnosis of AUC 92% (p<0.0001). […] By setting the cut-off MAPE score at ≥173 points, sensitivity and specificity for COVID-19 diagnosis were 83% and 82%, respectively, and the actual test positivity rate was 60% as compared to 6% of patients with MAPE score <173 points (odds ratio 23.04, 95% confidence interval [CI] 9.1-58.3, p-value <0.0001). | 2020-07-05 |
| 32620682 | Cancer diagnosis, among other clinical features, increases the risk of poor outcome of COVID-19 infection. | 2020-07-05 |
| 32620916 | Samples were studied with a combination of morphological and immunohistochemical techniques. | 2020-07-05 |
| 32621178 | With advances in diagnosis, treatment, and transfusion support, the prognosis of patients with thalassemia has improved over the past few decades. | 2020-07-05 |
| 32621238 | Reverse-transcription polymerase chain reaction (RT-PCR) assay is the preferred method of diagnosis of COVID-19 infection. […] We review important aspects of CT in COVID-19 infection from the justification of its use to specific scan protocols for optimizing radiation dose and diagnostic information. […] • Although chest CT has high sensitivity for diagnosis of COVID-19 pneumonia, CT findings are non-specific and overlap with other viral infections including influenza and H1N1. | 2020-07-05 |
| 32621757 | Furthermore, there is methodological heterogeneity in relation to the assessment of VTE (indications for screening, diagnostic methodology, etc). | 2020-07-05 |
| 32621814 | Rapid and early laboratory diagnosis of COVID-19 is the main focus of treatment and control. […] Point-of-care tests have the advantage of rapid, accurate, portable, low cost and non-specific device requirements, which provide great help for disease diagnosis and detection. […] This review will discuss the performance of different laboratory diagnostic tests and platforms, as well as suitable clinical samples for testing, and related biosafety protection. […] This review shall guide for the diagnosis of COVID-19 caused by SARS-CoV-2. | 2020-07-05 |
| 32622045 | Here, we briefly summarize several experimental techniques that individually inform on key physicochemical features of viral RNA genomes and their interactions with proteins. […] Each of these techniques provide important vantage points to understand the complexities of virus-host interactions, but we attempt to make the case that by integrating these and similar methods, more vivid descriptions of how viruses reprogram the cellular environment emerges. | 2020-07-05 |
| 32622375 | WHERE NEXT?: Careful clinical, diagnostic, and epidemiological studies are needed to help define the manifestations and burden of neurological disease caused by SARS-CoV-2. | 2020-07-06 |
| 32622411 | Academic research department and clinical diagnostic laboratory. | 2020-07-06 |
| 32622902 | Some of these are generic for the diagnostic accuracy paradigm, whereas others are more specific for tests for viruses. | 2020-07-06 |
| 32623037 | This study aimed to evaluate the diagnostic role of MPV in Covid patients with diabetes. | 2020-07-06 |
| 32623414 | Citation and co-citation network analysis are advantageous techniques to identify knowledge base in a scientific discipline. […] These techniques may help rehabilitation specialists to identify core articles efficiently. | 2020-07-06 |
| 32623480 | While several countries have chosen the almost complete lock-down for slowing down SARS-CoV-2 spread, the scientific community is called to respond to the devastating outbreak by identifying new tools for diagnosis and treatment of the dangerous COVID-19. […] More in general, our analysis provides indications for the set-up of the right biological molecular context for investigating spike RBD-ACE2 interactions for the development of new vaccines, diagnostic kits, and other treatments based on the targeting of SARS-CoV-2 spike protein. | 2020-07-06 |
| 32623505 | CT score is highly correlated with laboratory findings and disease severity and might be beneficial to speed-up diagnostic workflow in symptomatic cases. | 2020-07-06 |
| 32623963 | Accurate and early detection of infectious pathogens are crucial for transmission control, clinical diagnosis, and therapy. […] For a traditional reason, most immunological and microbiological laboratories are equipped with instruments designated for antibody-based assays in detection of infectious pathogens or clinical diagnosis. | 2020-07-07 |
| 32624074 | The aim of this study was to determine the evolution of lung abnormalities evaluated by quantitative CT techniques in patients with COVID-19 infection from initial diagnosis to recovery. | 2020-07-07 |
| 32624086 | The most challenging aspects reported are: (1) performing a physical examination in personal protective equipment (PPE), (2) being updated with rapidly evolving guidelines, and (3) staying focused on the possible COVID-19 clinical presentation without failing in differential diagnosis. | 2020-07-07 |
| 32624089 | Of these, 90 (99%) examinations were performed using a handheld device, and all were deemed diagnostic and provided sufficient information for the clinical care team. […] The protocol performed with handheld tablet ultrasound provides adequate diagnostic information of major cardiac complications of COVID-19 while decreasing sonographer contact and simplifying decontamination. | 2020-07-07 |
| 32624257 | PCR-based tests have emerged as the criterion standard for the diagnosis of infection. | 2020-07-07 |
| 32624352 | The COVID-19 pandemic has redefined the diagnostic imaging that is being practiced. | 2020-07-07 |
| 32624360 | Humans showing clinical symptoms of respiratory infections have been undergoing for the COVID-19 diagnostic test but many infected people and few pets confirmed with SARS-CoV-2 remained asymptomatic. | 2020-07-07 |
| 32624376 | The provisional diagnosis proposed can be further developed with continued review of literature, wider cooperation and teamwork with Allopathic physicians and access to clinical data as well as direct clinical assessment of COVID-19 patients. | 2020-07-07 |
| 32624431 | Both signs have been hypothesized to increase the diagnostic accuracy of LU for COVID-19 interstitial pneumonia. | 2020-07-07 |
| 32625198 | Likewise, the repurposing of antimalarials for treatment of COVID-19 shared symptoms and the shift in focus from the production of malaria rapid diagnostic tests (RDTs) to COVID-19 RDTs is a cause for concern in malaria-endemic regions. | 2020-07-07 |
| 32626680 | The diagnostic performance of the leucocyte subsets and other parameters were compared using the area under the receiver operating characteristic curve (AUC). | 2020-07-07 |
| 32626870 | Based on the normative standards issued by the National Health Commission of China, consensus on clinical trial management formulated by the organization of clinical research, and regulations for the diagnosis and treatment of oral diseases during public health emergencies by Chinese Stomatological Association, we drafted the guideline for clinical research of oral diseases, with a view to provide reference for the clinical studies of oral diseases under the first level response to major public health emergencies. | 2020-07-07 |
| 32626871 | For these three problems, we invited the experts from the Society of Oral Medicine, Shanghai Stomatological Association and the Oral Mucosal Disease Specialist Alliance Organization of Shanghai Ninth People’s Hospital Group to write the recommendation on the diagnosis and treatment of oral mucosal disease during prevention and control stage of novel coronavirus infection, in order to provide references for oral mucosal disease medical physicians and patients in this special period. […] This recommendation will be updated according to the situation of epidemic prevention and control in China and the new relevant diagnosis and treatment plans. | 2020-07-07 |
| 32626872 | During the epidemic period of COVID-19, due to the particularity of diagnosis and treatment of oral diseases, there is great challenges for how to deal with various types of dental emergency. […] In order to prevent and control the epidemic situation strictly, and to perform a scientific and orderly clinical diagnosis and treatment of dental emergency, this article provided suggestions on personnel management training, procedures and treatment, protection and disinfection of dental emergency during COVID-19 epidemic, and reference for dental institutions and medical staff. | 2020-07-07 |
| 32627534 | To contain those viruses, accurate and fast diagnosis followed by effective isolation and treatment of patients are pivotal at the early stage of virus breakouts. […] As of July 2020, more than 100 kits for COVID-19 diagnosis on the market have been surveyed in this review, while emerging sensing techniques for SARS-CoV-2 are also discussed. […] Therefore, we discuss guidelines to select diagnostic kits at different outbreak stages of the Panic Zone viruses, SARS-CoV-2 in particular. | 2020-07-07 |
| 32627622 | Through a deeper understanding of pathogenesis, it will be possible to develop more effective diagnosis and therapy. | 2020-07-07 |
| 32628049 | In this review, a large study was conducted on the detection techniques and quantitative determination methods of CQ and its related metabolites. | 2020-07-07 |
| 32628131 | No patient we surveyed reported a diagnosis of COVID-19. | 2020-07-07 |
| 32628399 | Advances in early diagnosis and treatment of diseases using minimally invasive procedures has led to an increase in the number of cases in locations outside the operating room. | 2020-07-07 |
| 32628534 | Antibodies to SARS-CoV-2 demonstrate infection when measured at least 14 days after symptom onset, are associated with clinical severity, and provide valuable diagnostic support in patients who test negative by NAAT but remain clinically suspicious for COVID-19. | 2020-07-07 |
| 32628637 | Although the COVID-19 incidence remained considerably lower in Sardinia than in the North Italy regions, which were the most affected, the field of prenatal screening and diagnosis was modified because of the emerging pandemic. | 2020-07-07 |
| 32628931 | Diagnostic VL was significantly lower in hospitalized patients than in patients not hospitalized (log10 VL = 3.3 versus 4.0; P = 0.018) after adjusting for age, sex, race, body mass index, and comorbidities. | 2020-07-07 |
| 32629147 | Patients with a positive COVID-19 diagnosis were given a questionnaire consisting of general questions (age, sex, date of symptoms, smoking history, concomitant diseases), questions about the most obvious symptom at presentation (one option only), the severity and frequency of symptoms (general and ENT), and STL (recovery time and degree of recovery). | 2020-07-07 |
| 32629425 | The following parameters of COVID-19 were reported daily: signs/symptoms; diagnosis by reverse transcriptase-polymerase chain reaction; absence of symptoms for ≥14 days; total deaths; and number of health care workers isolated with suspected COVID-19. | 2020-07-07 |
| 32629791 | Within the complex framework of anti-COVID-19 health management, where the criteria of diagnostic testing, the availability of public-health resources and services, and the applied anti-COVID-19 policies vary between countries, the reliability and accuracy in the modeling of temporal spread can prove to be effective in the worldwide fight against the disease. | 2020-07-08 |
| 32630601 | The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide has highlighted the importance of reliable and rapid diagnostic testing to prevent and control virus circulation. […] Dozens of monoplex in-house RT-qPCR assays are already available; however, the development of dual-target assays is suited to avoid false-negative results caused by polymorphisms or point mutations, that can compromise the accuracy of diagnostic and screening tests. […] We demonstrated that combining two single systems into a dual-target assay (with or without an MS2-based internal control) did not impair performances, providing a potent tool adapted for routine molecular diagnosis in clinical microbiology laboratories. | 2020-07-08 |
| 32630746 | Considerable scientific progress was recorded regarding SARS-CoV-2 infection in terms of genomic structure, diagnostic tools, viral transmission, mechanism of viral infection, symptomatology, clinical impact, and complications, but these data evolve constantly. | 2020-07-08 |
| 32631317 | The serum LDH levels were determined at diagnosis and follow-up visits. […] At diagnosis, significant differences in LDH levels were found between non-severe and severe group (P < 0.05). | 2020-07-08 |
| 32631358 | Usually, spatial smoothing techniques are used to map health outcomes, and rarely uncertainty of the spatial predictions are assessed. | 2020-07-08 |
| 32631405 | The inclusion criteria are as follows: (1) aged between 20 and 60 years, (2) both male and female patients with COVID-19, (3) clinical or definitive diagnosis (using polymerase chain reaction (PCR) test), (4) patients have not participated in other clinical trials, and (5) no renal or hepatic abnormalities. | 2020-07-08 |
| 32631426 | The total number of confirmed cases and deaths would increase by 8.72 and 9.44%, respectively, due to a 1-day delayed diagnosis in non-isolated infected patients. […] Postponing the relaxation of isolation, early diagnosis, patient isolation, broad close-contact tracing, and strict monitoring of infected persons could effectively control the COVID-19 epidemic. | 2020-07-08 |
| 32631458 | The interval between illness onset and diagnosis (OR = 1.056, 95% CI: 1.012-1.101) and interval between illness onset and admission (OR = 1.048, 95% CI: 1.009-1.087) were independent significant predictors of illness severity. | 2020-07-08 |
| 32631575 | Furthermore, due to suboptimal testing capabilities, an early clinical diagnosis is not always possible. | 2020-07-08 |
| 32631626 | To validate the British Society of Thoracic Imaging issued guidelines for the categorisation of chest radiographs for coronavirus disease 2019 (COVID-19) reporting regarding reproducibility amongst radiologists and diagnostic performance. | 2020-07-08 |
| 32632356 | AI techniques can also help disseminate vital information across the globe and reduce the spread of false information about COVID-19. | 2020-07-08 |
| 32632635 | Data sources were the clinical reports of patients admitted during the first month of lockdown and discharged with a confirmed diagnosis of stroke or TIA. | 2020-07-08 |
| 32632825 | There have been significant advances in the diagnosis and treatment of cardiovascular disease; however, racial disparities continue to create inequity in the medical community especially for African Americans. | 2020-07-08 |
| 32633068 | We performed a systematic screening for the diagnosis of deep vein thrombosis (DVT) by lower limb vein compression ultrasonography (CUS) in consecutive non-ICU patients hospitalized for COVID-19, independent of the presence of signs or symptoms of DVT. | 2020-07-08 |
| 32633414 | According to the latest guidelines published by the World Health Organization (WHO), the diagnosis of COVID-19 must be confirmed by quantitative reverse transcription polymerase chain reaction (rRT-PCR) or gene sequencing of specimen obtained from throat, sputum and blood samples. […] However, the limitations due to logistics, as well as low sensitivity and specificity diagnostic tools currently available have been reported as the main cause of high incidence of either false-negative or positive results. […] The purpose of the present translational research protocol is to discuss and present the original findings from our research team on new diagnostic technique to detect four Coronaviridae family members (SARS-CoV-2, SARS-CoV, HCoV and MERS-CoV), highlighting the methodology, the procedure and the possible advantages. […] This procedure based on rRT-PCR could be of great help to decisively validate the results obtained from more conventional diagnostic procedures such as chest computed tomography (CT) imaging and chest ultrasound. […] This translational diagnostic tool will assist emergency and primary care clinicians, as well as out-of-hospital providers, in effectively managing people with suspected or confirmed SARS-CoV-2. | 2020-07-08 |
| 32633712 | Women hospitalized in ICUs had lower lymphocyte count at diagnosis (median 0.77 × 109 cells/L) than women not hospitalized in ICUs (median lymphocyte count 1.15 × 109 cells/L). […] Clinical and laboratory evaluation of SARS-CoV-2-positive pregnant women at the time of diagnosis can identify patients at risk for ICU hospitalization. | 2020-07-08 |
| 32633720 | The platform holds tremendous potential for scaling up curation throughput, thus enabling EHR-powered early disease diagnosis. | 2020-07-08 |
| 32633733 | Using a combination of enhanced sampling molecular dynamics techniques and non-equilibrium alchemical transformations with full atomistic details, we have shown that hydroxychloroquine (HCQ) may act as a mild inhibitor of important functional proteins for SARS-CoV2 replication, with potency increasing in the series PLpro, 3CLpro, RdRp. | 2020-07-08 |
| 32633840 | The inclusion of avidity determination into regular diagnostic procedures has allowed to resolve such “atypical” serological constellations. […] The potential use of avidity determination for the diagnosis of COVID-19, for risk assessment, epidemiological studies, analysis of cross reactions, as well as for the control of vaccination programs is suggested and discussed. | 2020-07-08 |
| 32633856 | Symptoms such as fever or cough, and signs such as oxygen saturation or lung auscultation findings, are the first and most readily available diagnostic information. […] Such information could be used to either rule out COVID-19 disease, or select patients for further diagnostic testing. […] To assess the diagnostic accuracy of signs and symptoms to determine if a person presenting in primary care or to hospital outpatient settings, such as the emergency department or dedicated COVID-19 clinics, has COVID-19 disease or COVID-19 pneumonia. […] These factors make it very difficult to determine the diagnostic properties of these signs and symptoms from the included studies. […] We hope that future updates of this review will be able to provide more information about the diagnostic properties of signs and symptoms in different settings and age groups. […] The individual signs and symptoms included in this review appear to have very poor diagnostic properties, although this should be interpreted in the context of selection bias and heterogeneity between studies. […] Results from such studies could inform subsequent management decisions such as self-isolation or selecting patients for further diagnostic testing. | 2020-07-08 |
| 32634004 | In conclusion, FPs in Nigeria are helping to reduce the scourge of COVID-19 through patient education and innovative healthcare delivery that does not put patients at increased risk of the disease whilst promptly recognising potential COVID-19 patients and referring them for early diagnosis and treatment. | 2020-07-08 |
| 32634024 | Commonly used survival analysis techniques, such as the Kaplan-Meier method, often are not appropriate for such situations. | 2020-07-08 |
| 32634229 | Laboratory tests are an integral part of the diagnosis and management of patients; however, these tests are far from perfect. […] During the current global pandemic of COVID-19 (coronavirus disease 2019), multiple assays with unknown clinical sensitivity and specificity have been rapidly developed to aid in the diagnosis of the disease. […] Hence, using this situation as an clinical example, the goal of this article is to clarify the key factors that influence the PPV and NPV yielded by diagnostic testing, By doing so, we hope to offer health-care providers information that will help them better understand the potential implications of utilizing these test results in clinical patient management. | 2020-07-08 |
| 32634438 | Other emerging non-conventional drug discovery techniques such as bioinformatics and cheminformatics, structure-based drug design, network-based methods for prediction of drug-target interactions, artificial intelligence (AI) and machine learning (ML) and phage technique could provide alternative routes to discovering potent Anti-SARS-CoV2 drugs. | 2020-07-08 |
| 32634550 | The lack of specific treatment and gold-standard diagnostic system has made the situation more complicated. […] Efforts have led to production of several diagnostic kits that are associated with limitations such as inadequate sensitivity and accuracy. | 2020-07-08 |
| 32634602 | A total of 257 patients with a COVID-19 diagnosis were included in this study between 3 March 2020 and 14 April 2020. | 2020-07-08 |
| 32634734 | Search for an open PFO after a large drop in arterial oxygen saturation can be performed at the bedside with a variety of well-established techniques including bedside echocardiography, nitrogen washout test, and imaging studies. | 2020-07-08 |
| 32634827 | Average risk ratio comparing 30-day composite outcome of all-cause death, severe Covid-19 diagnosis or intensive care unit (ICU) admission for men versus women standardized to the age and comorbidity distribution of all patients were derived from multivariable Cox regression. […] Alcohol diagnosis, diabetes, hypertension, sleep apnea, prior MI and IHD (all P<0.001) as well as AF, stroke and HF (all P=0.01) were more often seen in men, and so was CKD (P=0.03). […] Obesity diagnosis (P<0.001) were more often seen in women. | 2020-07-08 |
| 32634855 | However, the elderly patients manifested minor clinical symptoms and atypical changes in chest CT images, which usually lead to misdiagnosis or delayed diagnosis. | 2020-07-08 |
| 32635180 | We used computer-based immunoinformatic analysis and the newly resolved 3-dimensional (3D) structures of the SARS-CoV-2 S trimeric protein, together with analyses of the immunogenic profiles of SARS-CoV, to anticipate potential B-cell and T-cell epitopes of the SARS-CoV-2 S protein for vaccine design, particularly for peptide-driven vaccine design and serological diagnosis. […] The structure-based immunoinformatic analysis for the SARS-CoV-2 S protein in this study may improve vaccine design, diagnosis, and immunotherapy against the pandemic of COVID-19. | 2020-07-09 |
| 32635234 | Point-of-care (POC) diagnostic services are commonly associated with pathology laboratory services. […] The question is “how can POC diagnostic services be integrated into health services in way that is useful and acceptable in the COVID-19 era?”. | 2020-07-09 |
| 32635444 | Serological diagnostic tests are being increasingly used to provide a broader understanding of COVID-19 incidence and to assess immunity status in the population. […] However, there are discrepancies between claimed and actual performance data for serological diagnostic tests on the market. […] The findings of this review highlight the need for ongoing independent evaluations of commercialized COVID-19 diagnostic tests. | 2020-07-09 |
| 32635743 | Loop-mediated isothermal amplification (LAMP) is a versatile technique for detection of target DNA and RNA, enabling rapid molecular diagnostic assays with minimal equipment. […] The global SARS-CoV-2 pandemic has presented an urgent need for new and better diagnostic methods, with colorimetric LAMP utilized in numerous studies for SARS-CoV-2 detection. […] Here we report the use of guanidine hydrochloride and combined primer sets to increase speed and sensitivity in colorimetric LAMP, bringing this simple method up to the standards of sophisticated techniques and enabling accurate, high-throughput diagnostics. | 2020-07-09 |
| 32636075 | Before a diagnosis of coronavirus disease 2019 (COVID-19) is made, these patients with negative chest CT findings may be ignored, causing the possibility of virus transmission. | 2020-07-09 |
| 32636083 | There is a need for the health system, specially in developing countries such as in Pakistan, to combat such a novel disease by rapid, accurate, and high quality diagnostic testing in order to screen suspected cases and also surveillance of the disease. […] A rapid, accurate and low-cost diagnostic point-of-care device is needed for timely diagnosis of COVID-19 and is essential to combat such outbreaks for compelling preventive measures against the disease spread. […] This review is to highlight the importance of point-of-care diagnostics device for robust and accurate diagnosis of COVID-19 in physician offices and other urgent healthcare-type settings and encourage academics and stake holders towards advancement in order to control outbreaks and develop the public health surveillance system. | 2020-07-09 |
| 32636116 | The girl still has a diagnosis of aplastic anemia and requires specialist therapy. | 2020-07-09 |
| 32636131 | Based on the national hospitalisation database [Programme de médicalisation des systèmes d’information (PMSI)], all patients admitted to the main public hospitals for a principal diagnosis of myocardial infarction or birth during the 2nd to the 14th week of 2020 were included. […] These were compared with the average number of patients admitted for the same diagnosis during the same time window in 2018 and 2019. | 2020-07-09 |
| 32636214 | The clinical performances of six molecular diagnostic tests and a rapid antigen test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were clinically evaluated for the diagnosis of coronavirus disease 2019 (COVID-19) in self-collected saliva. […] Of the 103 samples, viral RNA was detected in 50.5 to 81.6% of the specimens by molecular diagnostic tests, and an antigen was detected in 11.7% of the specimens by the rapid antigen test. […] The rapid antigen test alone is not recommended for an initial COVID-19 diagnosis because of its low sensitivity. | 2020-07-09 |
| 32636542 | Diagnostic tests for the coronavirus infection 2019 (COVID-19) are critical for prompt diagnosis, treatment and isolation to break the cycle of transmission. […] A positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR), in conjunction with clinical and epidemiologic data, is the current standard for diagnosis, but several challenges still exist. […] Serological assays help to understand epidemiology better and to evaluate vaccine responses but they are unreliable for diagnosis in the acute phase of illness or assuming protective immunity. | 2020-07-09 |
| 32636930 | Bilio-pancreatic endoscopy is considered a high-risk procedure for cross-contamination and, even though it is not directly involved in COVID-19 diagnosis and management, its reorganization is crucial to guarantee high standards of care minimizing the risk of SARS-CoV2 transmission among patients and health-care providers. […] The aim of this article is to discuss the approach to bilio-pancreatic endoscopy in the COVID-19 era with focus on diagnostic algorithms, indications, management of the endoscopic room, proper use of Personal Protective Equipment and correct reprocessing of instrumentation. | 2020-07-09 |
| 32637266 | In general, we recommend obtaining lithium levels in all patients who have been taking lithium and have the diagnosis of COVID-19. | 2020-07-09 |
| 32637987 | Detailed clinical and paraclinical data were collected from cases where the diagnosis of COVID-19 was confirmed through RNA PCR, or where the diagnosis was probable/possible according to World Health Organization criteria. | 2020-07-09 |
| 32638053 | Ultrasonography (US) is one of the most common diagnostic imaging tests in children. | 2020-07-09 |
| 32638199 | Inadequate knowledge and incorrect attitudes among HCWs can directly influence practices and lead to delayed diagnosis, poor infection control practice, and spread of disease. | 2020-07-09 |
| 32638344 | The potential differences between a clinical diagnosis of coronavirus disease 2019 (COVID-19) (i.e., symptoms without positive virus test) and a microbiological diagnosis (i.e., positive virus test results) of COVID-19 are not known. […] This study explored the differences between the two types of COVID-19 diagnosis among older patients in terms of clinical characteristics and outcomes. […] Patients who met the criteria for clinical diagnosis with negative virus test results were assigned to the clinical diagnosis group, whereas those with positive virus test results were assigned to the microbiological diagnosis group. […] The clinical and microbiological diagnosis groups demonstrated significant differences in outcomes and in the majority of laboratory findings. | 2020-07-09 |
| 32638613 | The diagnosis of novel coronavirus disease 2019 (COVID-19) has been a challenge in many countries due to nonspecific symptoms and variable incubation period. […] Many studies have reported high sensitivities of CT scans and suggested that they can be used in the diagnosis of COVID-19 alongside reverse transcriptase PCR. […] Therefore, new multicentric studies in different countries are needed to better understand the role of CT scans in COVID-19 diagnosis. […] In this report, we will discuss the clinical relevance of each test and the current Centers for Disease Control and Prevention and American College of Radiology recommendations regarding the use of imaging in the diagnosis of COVID-19. | 2020-07-09 |
| 32638712 | The patient-level diagnostic accuracy relative to RNA(±) after 10 days displayed 88% sensitivity (95% CI 75-95) and 75% specificity (95% CI 22-99), although specificity compared with historical controls was 100% (95%CI 91-100). | 2020-07-09 |
| 32638902 | Management of cardiac arrest occurring during mechanical ventilation or during prone positioning demands particular ventilator settings and rescuer positioning for chest compressions which deviate from standard cardiopulmonary resuscitation techniques. | 2020-07-09 |
| 32639251 | Five of eight patients had a previous diagnosis of epilepsy, suggesting that pre-existing epilepsy can be a potential risk factor for COVID-19-associated neurological manifestations. | 2020-07-09 |
| 32639511 | This hypothesis-generating diagnostic study examined a cohort of patients with severe degenerative aortic valve stenosis or chronic postinfarction heart failure, as well as age-matched healthy control participants. | 2020-07-09 |
| 32639569 | A diagnostic survey was distributed by a large national newspaper (De Telegraaf) and a popular social influencer (Govert Sweep) on March 17, 2020, and was completed by 16 072 participants. […] This diagnostic information was used to design infographics and a video targeted at repairing these gaps in behavior. | 2020-07-09 |
| 32639570 | The findings of this cohort study suggest that screening based on conventional COVID-19 symptoms or corresponding examination findings of febrile respiratory illness may not possess the necessary sensitivity for early diagnostic suspicion, at least in the prehospital emergency setting. | 2020-07-09 |
| 32639679 | The mechanism of this finding is still unclear but the differential diagnosis should include thrombotic microangiopathy related to direct or indirect-through the cytokine cascade-damage by the SARS-CoV-2 on the endothelium of brain’s vessels, as well as mechanisms similar to the hypoxemia brain-blood-barrier injury. | 2020-07-09 |
| 32641059 | This work aimed to provide insight on the newly emerged COVID-19, in the hope to gain a better understanding on the general overview, epidemiology, transmission, clinical features, diagnosis, treatment, and clinical outcomes as well as the prevention and control of COVID-19. | 2020-07-10 |
| 32641133 | We will use the techniques of Semi-Directed Interviews of Open and In-depth Questions, socio-demographic and health data sheets, and Field Diaries. | 2020-07-10 |
| 32641154 | Randomised, parallel 3-arm (1:1:1 ratio), open-label, Phase IV platform trial of immunomodulatory therapies in patients with late stage 1 or stage 2 COVID-19-related disease, with a diagnosis based either on a positive assay or high suspicion of COVID-19 infection by clinical and/or radiological assessment. | 2020-07-10 |
| 32641170 | The mainstay of diagnostic testing for coronavirus disease 2019 is molecular polymerase chain reaction testing of a respiratory specimen, obtained with a viral swab. | 2020-07-10 |
| 32641394 | Excluding breast surgery, laparoscopy was the most used procedure (43/126, 34.1%). 15 patients had a postoperative complication (15/126, 11.9%); only in 2 patients (2/15 13.3%) were there reports of Clavien-Dindo grade 3 or 4 complications. 6 patients tested positive for COVID-19 following a PCR diagnostic test, and these surgeries were cancelled. | 2020-07-10 |
| 32641443 | This case demonstrates the importance of heightened awareness that not all urticarial rashes represent spontaneous urticaria and as a consequence, this may result in misdiagnosis and ultimately delayed diagnosis. | 2020-07-10 |
| 32641471 | COVID-19, severe acute respiratory syndrome (SARS) and other HCoV patients were identified by diagnosis codes and/or virological results. | 2020-07-10 |
| 32641867 | This is of particular importance to pancreatic cancer, given that standard diagnostic modalities such as endoscopy may be restricted, and that disease biology precludes significant delays in treatment. | 2020-07-10 |
| 32641875 | This review will discuss about the current invitro diagnostic methods used worldwide for the early and accurate diagnosis of COVID-19. […] Currently the nucleic acid based polymerase chain reaction is used as the reliable diagnostic platform and antigen/antibody detection immunoassays are playing the role of screening tests for early detection and prognosis in COVID-19 treatment. | 2020-07-10 |
| 32641984 | Quantitative nucleic acid testing has become the gold standard for diagnosis and guiding clinical decisions regarding the use of antiviral therapy. […] This brief review will be useful for the accurate diagnosis and timely treatment of the new coronavirus pneumonia. | 2020-07-10 |
| 32642164 | Patients were likely had normal procalcitonin, creatinine, alanine aminotransferase, creatine kinase and lactate dehydrogenase levels at diagnosis. […] No specific symptom was helpful in the diagnosis of 2019-nCoV infection, but relatively low WBC and lymphocyte level might be suggestive to diagnosis. | 2020-07-10 |
| 32642364 | However, these patients may need routine diagnostic investigations including chest computed tomography and chest tomography angiogram scans (CT and CTA) to rule out other potential differential diagnoses and guide management. | 2020-07-10 |
| 32642390 | In a pandemic, often atypical presentations of this new disease have to be considered as differentials for early diagnosis and treatment of life-threatening conditions. | 2020-07-10 |
| 32642757 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia is a newly recognized disease, and its diagnosis is primarily confirmed by routine RT-PCR detection of SARS-CoV-2. […] This case has highlighted that false negative results could be present in the routine RT-PCR diagnosis, especially with virus variation. […] At the moment, Nanopore pathogen sequencing and antibody detection have been found effective in clinical diagnosis. | 2020-07-10 |
| 32643136 | A diagnosis of Acute Inflammatory Demyelinating Polyradiculoneuropathy (AIDP) subtype of GBS was then made. | 2020-07-10 |
| 32643218 | We highlight alternative molecular detection techniques used for developing novel COVID-19 diagnostics on the horizon. | 2020-07-10 |
| 32643469 | In this context, a differential diagnosis is essential for the correct management of COVID-19 pregnant women. | 2020-07-10 |
| 32643529 | The MolPort database that contains over 100,000 NPs was screened and filtered using molecular docking techniques. | 2020-07-10 |
| 32643596 | Although the genome of this novel viral RNA was sequenced quickly and testing kits were manufactured to assist in combatting COVID-19, the diagnosis and treatment will remain relatively unsuccessful until the pathology of this disease is fully understood. | 2020-07-10 |
| 32643909 | Later, she developed type 2 respiratory failure and carbon dioxide narcosis because of delay in diagnosis of severe, near-complete postintubation tracheal stenosis due to over suspicion of COVID-19 during the current pandemic. | 2020-07-10 |
| 32644268 | A literature review was conducted using Google Scholar® and MEDLINE®/PubMed® to identify current available evidence regarding the sensitivity of CT chest compared with RT-PCR for the diagnosis of COVID-19-positive patients. […] A total of 20 articles were identified that addressed the question of sensitivity of CT for diagnosis of symptomatic and asymptomatic COVID-19-positive patients. […] CT chest was a better diagnostic modality and capable of detecting active infection earlier in the time course of infection than RT-PCR in symptomatic patients. | 2020-07-10 |
| 32645053 | We investigated the diagnostic accuracy of CT using RT-PCR for SARS-CoV-2 as reference standard and investigated reasons for discordant results between the two tests. […] Diagnostic accuracy was calculated. […] The accuracy of chest CT in symptomatic ED patients is high, but used as a single diagnostic test, CT can not safely diagnose or exclude COVID-19. | 2020-07-10 |
| 32645276 | In this review, we provide information regarding the epidemiology, serological and molecular diagnosis, origin of SARS-CoV-2 and its ability to infect human cells, and safety issues. | 2020-07-10 |
| 32645347 | Serological surveys are a valuable tool to assess the extent of the epidemic, given the existence of asymptomatic cases and little access to diagnostic tests. | 2020-07-10 |
| 32645523 | The combination of numerical encoding techniques and digital signal processing methods are becoming increasingly important in handling large genomic data. | 2020-07-10 |
| 32645620 | By moving the diagnostic process out of the hospital or epilepsy center, it becomes possible to overcome growing gaps in neurology services. | 2020-07-10 |
| 32645630 | Comorbidities and delay in diagnosis were significantly associated with case mortality. | 2020-07-10 |
| 32645633 | In this review, we have discussed the antibody discovery and molecular and biological design of antibody fragments as inspiring therapeutic and diagnostic agents against viral targets. | 2020-07-10 |
| 32645826 | In Germany at present, 4398 suspected case reports for the diagnosis of SARS-CoV-2 infections among health and social workers have been filed. | 2020-07-11 |
| 32646502 | Patients will be followed-up by specialist physicians and Primary Health Care professionals. - Men and women. - Age between 18 and 75 years old. - Diagnosed SARS-CoV-2 infection, by PCR and/or IgM+ antibody test and/or antigen test. - Clinical diagnosis of lung involvement: (respiratory symptoms +/- pathological auscultation +/- O2 desaturation) - Chest X-ray with mild-moderate alterations or normal. - Patients who give their verbal informed consent in front of witnesses, which will be reflected in the patients’ medical records. - Oxygen desaturation below 93% or P02 < 62. - Moderate-severe dyspnea or significant respiratory or general deterioration that makes admission advisable. - Chest X-ray with multifocal infiltrates. - Insulin-dependent diabetes with poor control or glycaemia in the emergency room test greater than 300 mg/ml (fasting or not). - Other significant comorbidities: Severe renal failure (creatinine clearance < 30 mL/min); cirrhosis or chronic liver disease, poorly controlled hypertension. - Heart rhythm disturbances (including prolonged QT). - Severe immunosuppression (HIV infection, long-term use of immunosuppressive agents); cancer. - Pregnant or breast-feeding women. - Patients under use of glucocorticoids for other diseases. - History of allergy or intolerance to any of the drugs in the study (prednisone, azithromycin or hydroxychloroquine). - Patients who took one or more of the study drugs in the 7 days prior to study inclusion. - Patients taking non-suppressible drugs with risk of QT prolongation or significant interactions. - Patients unwilling or unable to participate until study completion. - Participation in another study. | 2020-07-11 |
| 32646540 | Vaccination, diagnostic tests, and use of the Corona-Warn-App with quarantine could successfully control the spread of the coronavirus infection in the community. | 2020-07-11 |
| 32646731 | The work center, type of profession, COVID-19 infection, level of exposure, compliance with preventive measures, isolation (if required) and diagnostic tests carried out were collected. […] The determination of infection was made by differentiated rapid diagnostic test (dRDT), using a finger-stick whole-blood sample. | 2020-07-11 |
| 32646771 | This study presents a systematic review of artificial intelligence (AI) techniques used in the detection and classification of coronavirus disease 2019 (COVID-19) medical images in terms of evaluation and benchmarking. […] Results showed that no relevant study evaluated and benchmarked AI techniques utilised in classification tasks (i.e. binary, multi-class, multi-labelled and hierarchical classifications) of COVID-19 medical images. […] According to the discussed future challenges, the process of evaluation and benchmarking AI techniques used in the classification of COVID-19 medical images considered multi-complex attribute problems. […] Moreover, this study proposes a detailed methodology for the evaluation and benchmarking of AI techniques used in all classification tasks of COVID-19 medical images as future directions; such methodology is presented on the basis of three sequential phases. […] Firstly, the identification procedure for the construction of four decision matrices, namely, binary, multi-class, multi-labelled and hierarchical, is presented on the basis of the intersection of evaluation criteria of each classification task and AI classification techniques. […] Secondly, the development of the MCDA approach for benchmarking AI classification techniques is provided on the basis of the integrated analytic hierarchy process and VlseKriterijumska Optimizacija I Kompromisno Resenje methods. | 2020-07-11 |
| 32646881 | Methods: Information was obtained by survey responses from 35 countries on available radioisotopes, radiopharmaceuticals and kits for diagnostic and therapeutic use. | 2020-07-11 |
| 32646885 | The diagnosis was established using a standardized questionnaire or by review of in-patient hospital records. | 2020-07-11 |
| 32647056 | However, these comparisons are difficult to validate due to broad differences between countries such as socioeconomic status, demographic structure, rural vs. urban settings, time of arrival of the pandemic, number of diagnostic tests and criteria for testing, and national control strategies to limit the spread of COVID-19. | 2020-07-11 |
| 32647285 | Histopathologic evaluation of tissue from affected patients is crucial for diagnostic purposes, but also for advancing our understanding of the disease. […] We provide the protocols and the list of commercially available antibodies and probes for these assays, so they can be readily implemented in pathology laboratories and medical examiner offices for diagnostic and research purposes. | 2020-07-11 |
| 32647526 | To further characterize cerebrovascular disease (CVD) in COVID-19, we review the current literature of published cases and additionally report the clinical presentation, laboratory and diagnostic testing results of 12 cases with COVID-19 infection and concurrent CVD from two academic medical centers in Houston, TX, USA, between March 1 and May 10, 2020. | 2020-07-11 |
| 32647672 | The diagnosis and evaluation of familial outbreaks requires a collective consideration of epidemiological history, molecular detection methods, chest computed tomography (CT), and clinical symptoms. […] In the first admission diagnosis, according to the degree of clinical symptoms, the 8 patients were defined as mild type (4/8) or moderate type (4/8). | 2020-07-11 |
| 32647674 | Based on the lean management model, the research group established a process of less-link visits, which sees reduced contact between patients and physicians during diagnosis and treatment, and zero-contact consultation through lean workflow and value stream analysis. […] The median waiting time for image examination has been reduced from 40 to 3 minutes, and the moving distance has been shortened from 800 to 10 m; (V) the diagnosis and treatment process is facilitated by 5G, achieving zero contact between doctors and patients. | 2020-07-11 |
| 32647915 | FBG ≥7.0 mmol/l at admission is an independent predictor for 28-day mortality in patients with COVID-19 without previous diagnosis of diabetes. | 2020-07-11 |
| 32648546 | An estimated 8.9% (95% CI: 8.4%-9.3%) of infections in NYS were diagnosed, with diagnosis highest among adults aged 55 years or older (11.3%, 95% CI: 10.4%-12.2%). | 2020-07-11 |
| 32648845 | It also covers the latest literature on various hit molecules proposed by computational methods and experimental techniques. | 2020-07-11 |
| 32648899 | This review discusses current evidence regarding the pathophysiology, transmission, diagnosis, and management of COVID-19. […] Diagnosis is made by detection of SARS-CoV-2 via reverse transcription polymerase chain reaction testing, although false-negative test results may occur in up to 20% to 67% of patients; however, this is dependent on the quality and timing of testing. | 2020-07-11 |
| 32648950 | Childhood cancer is a highly curable disease when timely diagnosis and appropriate therapy are provided. | 2020-07-11 |
| 32649214 | Design: COVID-19 diagnostic testing data was analyzed. […] Results: Daily viral diagnostic testing capacity increased by greater than 3000 % (from 21 tests per day to 658 tests per day). […] Total viral diagnostic testing resulted by the core lab increased by 128 times over 22 days of test method validation and 826 times over the analysis period while average turn-around-time per day for send-out testing increased from 3.7 days to 21 days. | 2020-07-11 |
| 32649426 | The objective of this study was to assess the initial results of chest computed tomography (CT) standardized diagnostic criteria proposed by the Radiological Society of North America in coronavirus disease 2019 (COVID-19) compared with reverse transcription-polymerase chain reaction (RT-PCR). […] With RT-PCR as reference standard, the performance of the CT diagnostic criteria in diagnosing COVID-19 was assessed. […] The diagnostic performance was excellent, considering the area under the curve of 0.92 (95% CI, 0.84-0.99). […] Chest CT standardized diagnostic criteria had high specificity and positive predictive value for the diagnosis of COVID-19 when presenting a typical appearance. | 2020-07-11 |
| 32650037 | Furthermore, 66 nasopharyngeal swabs were tested to determine the diagnostic performances. […] We assessed the diagnostic performance between single- (NIID) and double-quencher (YCH) probes using 66 nasopharyngeal swabs. | 2020-07-11 |
| 32650110 | To determine the frequency of SARS-CoV-2 positive samples in a subset of patients consulting for primarily isolated acute (<7 days) loss of smell and to assess the diagnostic accuracy of olfactory/gustatory dysfunction for COVID-19 diagnosis in the overall population tested for COVID-19 in the same period. | 2020-07-11 |
| 32650523 | A total of 127 (62%) were male, 184 (91%) had a diagnosis of solid malignancy, and 103 (51%) had non-metastatic disease. | 2020-07-12 |
| 32650645 | The objective of this study is to characterize the effect of common pasteurization techniques on viruses in HM and non-HM matrices. | 2020-07-12 |
| 32650818 | Male and female patients above the age of 64 (i.e. ≥65 years of age) with COVID-19 diagnosis confirmed by SARS-CoV2 positive throat swab (PCR). | 2020-07-12 |
| 32650840 | Five early actions (early detection, early reporting, early diagnosis, early isolation, and early treatment) and four centralized responses (centralized coordination by experts, centralized allocation of resources, centralized placement of patients, and centralized provision of treatment) ensured effective prevention and control. | 2020-07-12 |
| 32650948 | This suggests no viral transmission during sexual contact and assisted reproductive techniques, although further data need to be obtained. | 2020-07-12 |
| 32650954 | Of the surveyed patients, 42% had cancelled diagnostic tests, 59% had cancelled medical consultations, 3.5% had cancelled treatments and 1% had cancelled interventions. | 2020-07-12 |
| 32650970 | The diagnosis was confirmed by reverse real-time PCR assay on a throat swab sample taken during the patient’s admission. | 2020-07-12 |
| 32651020 | Against the backdrop of the COVID pandemic, the scientific and medical communities are working with all deliberate speed with state-of-the-art technologies to develop diagnostic and therapeutic products that can identify, treat, and prevent infection with SARS-CoV-2. | 2020-07-12 |
| 32651106 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated coronavirus disease 2019 (COVID-19) pandemic has demanded rapid upscaling of in-vitro diagnostic assays to enable mass screening and testing of high-risk groups, and simultaneous ascertainment of robust data on past SARS-CoV-2 exposure at an individual and a population level. | 2020-07-12 |
| 32651152 | Information regarding symptoms was collected and all patients were simultaneously tested using two rapid diagnostic tests - RDTs (Combined - cRDT and Differentiated - dRDT). […] RT-qPCR is the technique of choice in the diagnosis of SARS-CoV-2 infection, but it is not exempt from false negatives. […] Our results show that patients who present mild or moderate symptoms with negative RT-qPCR, but with fever and/or anosmia, should be considered as suspicious cases and should be evaluated with other diagnostic methods. | 2020-07-12 |
| 32651306 | The mean (SD) time from illness onset to diagnosis was 2 (1) days. 54 children were asymptomatic, while eight had fever, and five cases had cough. | 2020-07-12 |
| 32651328 | All patients received a diagnosis of FTD during 2018-2019 according to international criteria. | 2020-07-12 |
| 32651556 | The recent spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exemplifies the critical need for accurate and rapid diagnostic assays to prompt clinical and public health interventions. […] Our goal was to make independent evaluations of primer-probe sets used in four common SARS-CoV-2 diagnostic assays. […] Our recommendation for SARS-CoV-2 diagnostic testing is to select an assay with high sensitivity and that is regionally used, to ease comparability between outcomes. | 2020-07-12 |
| 32651686 | Importantly, all medical staff must prevent nosocomial COVID-19 by minimizing the effects of aerosol spread and developing diagnostic and surgical procedures. | 2020-07-12 |
| 32651728 | In addition, the majority of participants felt that perception of or concern about future stigma related to a COVID-19 diagnosis or association of COVID-19 with the Jewish community was high and also significantly predicted distress and anxiety. | 2020-07-12 |
| 32651959 | This review systematically summarizes the immune-pathobiological characteristics, diagnosis, potential therapeutic options for the treatment and prevention of COVID-19 based on the current published literature and evidence. | 2020-07-12 |
| 32651978 | Gordon Schiff and Maria Mirica for the PRIDE (Primary Care Research in Diagnostic Errors) project, an initiative of the Betsy Lehman Center for Patient Safety and Brigham and Women’s Hospital Center for Patient Safety Research and Practice with support from the Gordon and Betty Moore Foundation. […] It highlights some of the key issues related to diagnostic accuracy issues for COVID-19 and beyond. | 2020-07-12 |
| 32652095 | Because these mitigation strategies may be necessary for the next 6 to 18 months to prevent recurrent peaks in disease prevalence, fewer objective measurements of lung function will alter the diagnosis and care of patients with chronic respiratory diseases. […] PFT, which includes spirometry, lung volume, and diffusion capacity measurement, is essential to the diagnosis and management of patients with asthma, COPD, and other chronic lung conditions. […] The adoption of some novel approaches may not merely replace but could improve existing management strategies and alter common diagnostic paradigms. | 2020-07-12 |
| 32652161 | This study aimed to evaluate the test performance of recently launched commercial immunoassays in serum and plasma samples. 51 serum samples from 26 patients with confirmed SARS-CoV-2 infection after end of quarantine and 25 control patients were analyzed using anti-SARS-CoV-2 IgG immunoassays from Roche, Euroimmun and Epitope to assess diagnostic sensitivity and specificity. 20 matching pairs of serum and plasma samples were included to analyze comparability between different specimens. […] Overall, a diagnostic sensitivity of 92.3%, 96.2-100% and 100% with a respective diagnostic specificity of 100%, 100% and 84-86% for the immunoassays from Roche, Euroimmun and Epitope were determined. […] The immunoassays from Euroimmun and Roche revealed a higher specificity than the Epitope assay without a substantial drop of diagnostic sensitivity. | 2020-07-12 |
| 32652443 | We investigated the medical records on the number of cancer diagnosis, cancer surgery, radiation therapy and scheduled chemotherapy conducted in Korea University Anam Hospital from January 1 to April 30, 2019 and from the same period in 2020. | 2020-07-12 |
| 32652454 | Chest CT plays an important role in the diagnosis and monitoring treatment response of this disease. | 2020-07-12 |
| 32652455 | For diagnosis, chest computed tomography is a conventional, noninvasive imaging modality that is very accurate for detection and evaluation of pneumonia and is an important adjunct to real-time reverse transcription polymerase chain reaction diagnosis of the virus. | 2020-07-12 |
| 32652499 | Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are crucial goals for health practitioners. […] This new methodology has potential to greatly improve initial screening for patients where PCR based diagnostic tools are limited. | 2020-07-12 |
| 32652520 | The diagnosis of SARS-CoV-2 infection was confirmed by oropharyngeal swab on reverse-transcription polymerase chain reaction assay. | 2020-07-12 |
| 32652813 | Diagnostic validation was achieved by two independent reference laboratories, the Instituto de Salud Carlos III, (Madrid, Spain), the Public Health England (Colindale, London, UK), and received the label CE-IVD. […] Results from reference laboratories 100% correlated with these obtained by using reference methods and showed 100% of diagnostic sensitivity and specificity. […] The CE-IVD GPS™ CoVID-19 dtec-RT-qPCR test, available worldwide with full analytical and diagnostic validation, is the more exclusive for SARS-CoV-2 by far. | 2020-07-12 |
| 32653819 | For over two centuries, autopsy has been recognized as a fundamental diagnostic technique, particularly for new or little-known diseases. […] To date, it is often considered obsolete giving the inadequacy to provide samples of a quality appropriate to the sophisticated diagnostic techniques available today. […] In our experience, the tissue sample collected for diagnosis and research were of quality similar to biopsy or surgical resections. […] We want to propose our experience, our main qualitative results and a few general considerations, hoping that they can be an incentive to use autopsy with a new procedure adjusted to match the diagnostic challenges of the third millennium. | 2020-07-13 |
| 32653890 | This paper reviews the different imaging modalities used in the diagnosis and treatment process of COVID-19, such as chest radiography, computerized tomography (CT) scan, ultrasound examination, and positron emission tomography (PET/CT) scan. […] Chest CT imaging is reported to be a more reliable, rapid, and practical method for diagnosis of COVID-19, and it can assess the severity of the disease and follow up the disease time course. […] In the absence of vaccines and treatments for COVID-19, prompt diagnosis and appropriate treatment are essential. | 2020-07-13 |
| 32654005 | Specific recommendations and reports have been released both at International and National level, regarding the diagnosis and management of COVID-19 in the elderly. | 2020-07-13 |
| 32654199 | Pre-existing procedures have been modified to allow healthcare professionals to work safely ensuring patients the necessary assistance with samples suitable for cellularity, fixation and staining for an accurate cytological diagnosis. | 2020-07-13 |
| 32654210 | The present review aims to enlighten the applications of transthoracic echocardiography for the diagnostic and therapeutic management of myocardial damage in COVID-19 patients. | 2020-07-13 |
| 32654267 | This review presents a report on the origin, transmission, symptoms, diagnosis, possible vaccines, animal models, and immunotherapy for this novel virus and will provide ample references for the researchers toward the ongoing development of therapeutic agents and vaccines and also preventing the spread of this disease. | 2020-07-13 |
| 32654387 | Five drivers were ranked with the highest probability to play a key role in the emergence of COVID-19 in pets: availability and quality of diagnostic tools, human density close to pets, ability of preventive/control measures to avoid the disease introduction or spread in a country (except treatment, vaccination and reservoir(s) control), current species specificity of the disease-causing agent and current knowledge on the pathogen. | 2020-07-13 |
| 32654533 | Implementation of the engineered surfaces in quartz crystal microbalance (QCM)-based detection techniques for the diagnosis of the novel coronavirus from oral swab samples is highlighted. | 2020-07-14 |
| 32654634 | Extensive diagnostic testing to trace and isolate the COVID-19 cases as well as basic income and economic support for those who are unable to work will be needed. | 2020-07-14 |
| 32654678 | The reported frequency of abuse, self-harm and thoughts of suicide/self-harm was higher among women, Black, Asian and minority ethnic (BAME) groups and people experiencing socioeconomic disadvantage, unemployment, disability, chronic physical illnesses, mental disorders and COVID-19 diagnosis. | 2020-07-14 |
| 32655021 | We included 43 patients with a past history of CKD and confirmed diagnosis of COVID-19. | 2020-07-14 |
| 32655742 | Rare bleeding complications such as psoas hematoma should be kept in mind in patients who become hemodynamically unstable, warranting prompt imaging for diagnosis and treatment with arterial embolization, thus eliminating need of surgical intervention. | 2020-07-14 |
| 32656001 | Testing capacity is also problematic in several countries, where diagnosis demand outnumbers available local testing capacity. […] Different scarcity scenarios were simulated, including symptomatic essential workforce management and absence of diagnostic tests. […] Machine learning models can be derived from widely available, quick, and inexpensive exam data in order to predict qRT-PCR results used in COVID-19 diagnosis. | 2020-07-14 |
| 32656033 | Our review aims to identify the various neurological manifestations in SARS-CoV-2 positive patients, which could be an added advantage in the early diagnosis and prevention of further complications of the nervous system. | 2020-07-14 |
| 32656050 | This case emphasizes the importance of continued investigation regarding diagnosis and treatment of COVID-19 and its related symptoms. | 2020-07-14 |
| 32656087 | The FP techniques for adult female patients include oocyte and embryo cryopreservation, which require both adequate ovarian reserve (OR) and controlled ovarian stimulation (COS) to promote multiple follicular growth. […] Here, we focus on the current conditions in terms of agreements and rules of FP procedures during this COVID-19 pandemic to achieve and provide useful recommendations for the adoption of these techniques in patients with cancer. | 2020-07-14 |
| 32656101 | CDC and WHO guidelines for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis only recommend synthetic fiber swabs for nasopharyngeal (NP) sampling. | 2020-07-14 |
| 32656303 | In a special issue of VirusDisease, “The global emergence of coronavirus in human”, various topics relating to emergence, potential cases, transmission dynamics, diagnosis, pathogenesis, food safety, therapeutic strategies and antiviral properties of Ayurveda products are covered. | 2020-07-14 |
| 32656306 | Although there are number of methods available for detection of virus and to combat this disease in the present pandemic situation, but these available diagnostic methods have their own limitations. […] Additional to the available diagnostic methods, there is a sudden surge for development of various of methods and platforms to diagnose the COVID-19. […] The review summarized the advantage and disadvantage of various diagnostic approaches being used presently for COVID-19, newer detection methods in developmental stage and the feasibility of advanced platforms like newer nano-sensor based on-the-spot detection technologies. | 2020-07-14 |
| 32656308 | In this context, technologies such as sequencing, Crispr and artificial intelligence are playing vital role in diagnosis and management of infectious disease in contrast to conventional methods. […] Despite of this, there is a need to have rapid and early diagnostic tools and systems that recognize infectious disease in asymptotic condition. | 2020-07-14 |
| 32656565 | Patients without computed tomography pulmonary angiography (CTPA)-proven PE diagnosis and those who were directly admitted to an intensive care unit (ICU) were excluded. | 2020-07-14 |
| 32656591 | Univariate analysis was conducted using standard techniques and logistic regression was used to determine the independent effect of blood type on intubation and/or death and positive testing. | 2020-07-14 |
| 32656618 | However, an optimal epidemiology-focused strategy for ‘safe-reopening’ (i.e., balancing between the economic and health consequences) remain unclear, particularly given the suboptimal disease surveillance and diagnostic infrastructure in these settings. | 2020-07-14 |
| 32656638 | The cases were divided into regular group, severe group and critically ill group according to the sixth edition scheme for COVID-19 diagnosis and treatment of China. | 2020-07-14 |
| 32656663 | In brief, an accurate remote and in person triage must be provided routinely and patients submitted to specific diagnostic tests prior to every major treatment or procedure (surgery, RT, and CT) or in case of suspicion for COVID-19 syndrome. | 2020-07-14 |
| 32656688 | The diagnosis of COVID-19 was confirmed by positive results of reverse transcriptase polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] There is no direct evidence of vertical mother-to-child transmission of SARS-CoV-2; however, a diagnosis of COVID-19 was made in a newborn two hours after delivery from a pregnant woman with COVID-19, based on the increased immunoglobulin levels and deranged liver function, suggesting that its possibility cannot be completely eliminated. | 2020-07-14 |
| 32656691 | A survey was sent out to patients with a confirmed diagnosis of IA. | 2020-07-14 |
| 32656794 | There is concern that reduced access to diagnosis and treatment can also lead to increased morbidity in patients with liver diseases and we may witness a delayed surge of hospitalizations related to decompensated liver disease after the COVID-19 pandemic has receded. | 2020-07-14 |
| 32657000 | The study concludes that the COVID-19 infodemic is full of false claims, half backed conspiracy theories and pseudoscientific therapies, regarding the diagnosis, treatment, prevention, origin and spread of the virus. | 2020-07-14 |
| 32657235 | Different learning techniques should be added to the curriculum, especially at the time which widespread panic and uncertainty are prevalent. | 2020-07-14 |
| 32657343 | In this context of a novel viral pandemic, clinical laboratories have developed multiple novel assays for SARS-CoV-2 diagnosis and for managing patients afflicted with this illness. | 2020-07-14 |
| 32657445 | Thus, echocardiography is integral in the timely diagnosis and clinical management of COVID-19 patients. | 2020-07-14 |
| 32657586 | The emergence of novel coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 coronavirus, has necessitated the urgent development of new diagnostic and therapeutic strategies. | 2020-07-14 |
| 32657601 | Real time polymerase chain reaction and radiography are the two main diagnostic methods. […] Guidelines from the Center for Disease Control and Prevention and the World Health Organization (WHO) should be followed for diagnostic and precautionary measures. | 2020-07-14 |
| 32657967 | This statute would overhaul existing regulatory framework by unifying the oversight of LDTs and commercial in-vitro diagnostic tests (IVDs) through the FDA. | 2020-07-14 |
| 32658022 | Patients were tested for SARS-CoV-2 with either molecular and/or serological techniques and screened for presentation of COVID-19. | 2020-07-14 |
| 32658359 | In order to update information gained, we provide a systematic overview of the skin lesions described in COVID-19 patients, discuss potential causative factors, and describe differential diagnostic evaluations. | 2020-07-14 |
| 32658740 | With the recent outbreak of COVID-19, fast diagnostic testing has become one of the major challenges due to the critical shortage of test kit. | 2020-07-14 |
| 32658837 | Six patients (2.8%) had a previous diagnosis of asthma. | 2020-07-14 |
| 32659100 | The goal of this study was to evaluate existing literature on telemedicine and assess overall image quality, diagnostic concordance, and patient and provider satisfaction with telemedicine technologies. […] English language studies with primary or secondary endpoints pertaining to image quality, diagnostic concordance, or patient or provider satisfaction were included. […] Studies assessing imaging quality and diagnostic concordance reported adequate results but with some heterogeneity. […] The literature supports telemedicine delivery of otorhinolaryngologic care as having achieved high rates of patient and provider satisfaction with adequate image quality and heterogeneity in diagnostic concordance. […] Variability in diagnostic accuracy was reported, but appears improved given proper clinical context. | 2020-07-14 |
| 32659214 | Demographic, clinical, laboratory, treatment, and outcome data were extracted from electronic medical records and compared between patients with moderate, severe, and critical disease (defined according to the diagnosis and treatment protocol for novel coronavirus pneumonia, trial version 7, published by the National Health Commission of China). | 2020-07-14 |
| 32659224 | The initial clinical features of SARS-CoV-2 infection are quite nonspecific and not all suspected patients can be tested to exclude or confirm the diagnosis. […] Increasing scientific evidence has shown that abnormalities in routine laboratory tests, particularly hematological tests, have the potential to indicate, in a quick, practical and economical way, the need for specific laboratory tests for the diagnosis of SARS-CoV-2 infection, besides assisting in the prognosis of the disease and in the optimization of its clinical monitoring. […] In order to address in a simple and practical way the various aspects related to SARS-CoV-2 infection, this review reports the history of the virus, the epidemiology and pathophysiology of COVID-19, with emphasis on its laboratory diagnosis, particularly in hematological changes found during the course of the disease. | 2020-07-14 |
| 32659293 | A special attention should be paid to pre-analytical and analytical requirements and to the proper collection of covariates affecting dose-exposure relationships (co-medications, use of specific organ support techniques and other clinical and para-clinical data). | 2020-07-14 |
| 32659413 | To collate the evidence on the accuracy parameters of all available diagnostic methods for detecting SARS-CoV-2. […] Studies reporting data on sensitivity or specificity of diagnostic tests for COVID-19 using any human biological sample were included. […] RT-PCR remains the gold standard for the diagnosis of COVID-19 in sputum samples. […] However, the combination of different diagnostic tests is highly recommended to achieve adequate sensitivity and specificity. | 2020-07-14 |
| 32659712 | For this, the Center for Virology, Medical University of Vienna was tasked by the Federal Ministry of Social Affairs, Health, Care and Consumer Protection to perform the first Austrian EQA on SARS-CoV-2 which was organised in cooperation with the Austrian Association for Quality Assurance and Standardization of Medical and Diagnostic Tests (ÖQUASTA). | 2020-07-14 |
| 32659713 | However, identifying such individuals requires accurate diagnostic tools. […] We compared the Aptima™ assay to two in-house real-time RT-PCR techniques, one running on the Panther Fusion™ module and the other on the MagNA Pure 96 and Light-Cycler 480 instruments. | 2020-07-14 |
| 32659729 | COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and spreading worldwide has become a serious challenge for the entire health care system as regards infection prevention, rapid diagnosis, and treatment. […] Lung ultrasound (LUS) is a dynamically developing diagnostic method used in intensive care, cardiology and nephrology, it can also be helpful in diagnosing and monitoring pneumonia. | 2020-07-14 |
| 32660185 | The pathogenesis of COVID-19 combined with liver injury in existing studies is still unclear, and relevant guidelines and expert consensuses are insufficient for clinical diagnosis and treatment. | 2020-07-15 |
| 32660204 | Fifty-two pregnant women were included, with confirmed COVID-19 diagnosis rate of 82.7%. | 2020-07-15 |
| 32660240 | Rapid diagnosis of the disease and isolation of patients are effective ways to prevent and control the spread of COVID-19. | 2020-07-15 |
| 32660335 | Nevertheless, development of robust teleNP protocols should expand availability of neuropsychology in both clinical and research applications while simultaneously decreasing assessment burden associated with traveling - sometimes long distances - for diagnostic neuropsychological evaluation. | 2020-07-15 |
| 32660611 | Key Inclusion criteria • Confirmed diagnosis of SARS-CoV-2 infection (eg, via polymerase chain reaction [PCR] and/or antibody test) presenting as severe COVID-19 requiring hospitalization • Severe pneumonia, acute lung injury, or ARDS confirmed by computed tomography (CT) or X-ray at Screening or within the 3 days prior to Screening, as part of the patient’s routine clinical care • Respiratory distress requiring mechanical ventilation, which can be either invasive (requiring endotracheal intubation) or non-invasive (with continuous positive airway pressure [CPAP] or bilevel positive airway pressure [BiPAP]) Key Exclusion criteria • Patient is not expected to survive for more than 24 hours • Patient is on invasive mechanical ventilation with intubation for more than 48 hours prior to Screening • Severe pre-existing cardiac disease (ie, NYHA Class 3 or Class 4, acute coronary syndrome, or persistent ventricular tachyarrhythmias) • Patient has an unresolved Neisseria meningitidis infection Excluded medications and therapies • Current treatment with a complement inhibitor • Intravenous immunoglobulin (IVIg) within 4 weeks prior to randomization on Day 1 Excluded prior/concurrent clinical study experience • Treatment with investigational therapy in a clinical study within 30 days before randomization, or within 5 half-lives of that investigational therapy, whichever is greater • Exceptions a. | 2020-07-15 |
| 32660684 | Diagnostic testing to identify patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays a key role to control the coronavirus disease (COVID-19) pandemic. […] While several countries have implemented the use of diagnostic testing in a massive scale as a cornerstone for infection control and surveillance, other countries affected by the pandemic are hampered by its limited testing capacity. […] Simulation studies to determine optimal pool size and pooling techniques have also been conducted. | 2020-07-15 |
| 32661507 | The general condition of the elderly should be considered during diagnosis and treatment. | 2020-07-15 |
| 32661509 | This finding has important implications for diagnosis, prevention, and control of COVID-19. | 2020-07-15 |
| 32661521 | The conclusions of this study should be interpreted with caution, and additional mitigation techniques consistent with the Centers for Disease Control and Prevention recommendations must be implemented in dental practices. | 2020-07-15 |
| 32661585 | Two-thirds performed at least one diagnostic/interventional procedure on COVID-19 patients. | 2020-07-15 |
| 32661780 | The Italian College of Breast Radiologists by the Italian Society of Medical Radiology (SIRM) provides recommendations for breast care provision and procedural prioritization during COVID-19 pandemic, being aware that medical decisions must be currently taken balancing patient’s individual and community safety: (1) patients having a scheduled or to-be-scheduled appointment for in-depth diagnostic breast imaging or needle biopsy should confirm the appointment or obtain a new one; (2) patients who have suspicious symptoms of breast cancer (in particular: new onset palpable nodule; skin or nipple retraction; orange peel skin; unilateral secretion from the nipple) should request non-deferrable tests at radiology services; (3) asymptomatic women performing annual mammographic follow-up after breast cancer treatment should preferably schedule the appointment within 1 year and 3 months from the previous check, compatibly with the local organizational conditions; (4) asymptomatic women who have not responded to the invitation for screening mammography after the onset of the pandemic or have been informed of the suspension of the screening activity should schedule the check preferably within 3 months from the date of the not performed check, compatibly with local organizational conditions. | 2020-07-15 |
| 32661881 | A diagnosis of diabetes is often an indicator of poor underlying metabolic health, and frequently people with diabetes have multiple risk factors for severe coronavirus disease 2019 (COVID-19), including cardiovascular and renal disease. | 2020-07-15 |
| 32661937 | Here we describe a case series of routinely seen pediatric diseases with delayed diagnosis due to different aspects of what we call “Corona-phobia”. […] What is New: • This case series describes 7 cases with delayed diagnosis of every-day pediatric diseases that were not caused by COVID-19 but were highly influenced by different aspects of “Corona-phobia”. […] • Our objective is to highlight the possibility that measures taken to mitigate this pandemic may lead to a substantial delay in the diagnosis of other non-COVID-19 related diseases. | 2020-07-15 |
| 32661945 | Symptomatic patients were referred to the Medical Imaging Center for diagnosis confirmation through CT scan. […] In summary, the present study indicated that in addition to GGO, peripheral distribution findings could be a vital diagnostic choice in COVID-19 patients. | 2020-07-15 |
| 32662041 | The patients were divided into four age groups (children [0-17 years], young adults [18-44 years], middle age [45-59 years], and senior [≥ 60 years]) according to their age after the diagnosis was made based on PCR test and clinical symptoms. […] A better understanding of the age differences in comorbidities, cluster onset, highest clinical classification, large/multiple GGO, numbers of lobes affected, and frequency of lobe involvement can be useful in the diagnosis of COVID-19 patients of different ages. | 2020-07-15 |
| 32662058 | Based on different categories of disease severity (asymptomatic, regional/systemic symptoms, hospitalisation, myocardial damage, and/or myocarditis), in this point-of-view article we offer the (sports) cardiologist or sports physician in the Netherlands a practical guide to pre-participation screening, and diagnostic and management strategies in all athletes >16 years of age after COVID-19 infection. | 2020-07-15 |
| 32662060 | The novel coronavirus infection introduced new guidelines for and approaches to the investigation of immunocompromised patients, so it is especially important not to forget the basis of differential diagnosis, to and adopt a thorough approach when assessing these complex patients. | 2020-07-15 |
| 32662129 | Meeting the diagnostic requirement for COVID-19-related PTSD was associated with younger age, male sex, living in a city, living with children, moderate and high perceived risk of COVID-19 infection, and screening positive for anxiety or depression. | 2020-07-15 |
| 32662342 | As soon as the causative pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified and its genome sequence determined, a laboratory diagnosis based on nucleic acid amplification technologies was quickly established and has played essential roles in the confirmation of a clinical diagnosis. […] Serological testing for antibodies against SARS-CoV-2 is becoming available for complementary diagnosis, identification of convalescent plasma, and epidemiologic studies. […] Nevertheless, with overwhelming numbers of patients and potentially large numbers of asymptomatic cases, clinical laboratories encounter enormous challenges in diagnostic approaches that can rapidly and accurately identify infected persons. | 2020-07-15 |
| 32662396 | The quality and type of specimen collection affect the sensitivity of real-time reverse transcriptase-PCR (rRT-PCR) for the diagnosis of SARS-CoV-2. […] The preliminary results revealed that higher SARS-CoV-2 RNA concentration and longer time for detection make self-collected sputum a preferable specimen for the diagnosis and follow-up of COVID-19 pneumonia. | 2020-07-15 |
| 32662399 | A 32-year-old medical practitioner presented to the emergency department with complaints of severe abdominal pain, fever, and vomiting, 1 week after the diagnosis of COVID-19. […] Laboratory and radiological investigations revealed the diagnosis of acute pancreatitis. | 2020-07-15 |
| 32662416 | Therefore, it is of the utmost importance to clarify eye involvement in COVID-19 in order to help with its diagnosis and to further prevent its transmission. | 2020-07-15 |
| 32662899 | A diagnosis of Guillain-Barré syndrome was made on the basis of clinical presentation, cerebrospinal fluid analysis, and electroneurography. | 2020-07-15 |
| 32663071 | In addition, institutions should have an operational strategy that consists of patient prioritization, screening, diagnostic testing, physical distancing, infection control, and follow-up surveillance. | 2020-07-15 |
| 32663256 | Individual and serial samples covered the time of initial diagnosis, during the disease course, and following recovery. | 2020-07-15 |
| 32663258 | Significant increases in workload were observed in the send-out laboratory section and for COVID-19 diagnosis (PCR) and management-related testing. | 2020-07-15 |
| 32663494 | Retrospective descriptive study of cases that met COVID-19 clinical diagnosis criteria or had a positive PCR test from February 27 to June 29, 2020. | 2020-07-15 |
| 32663601 | The 6MWT is a potential tool in the diagnosis of asymptomatic exercise-induced hypoxia in hospitalized COVID-19 patients prior to discharge. | 2020-07-15 |
| 32663788 | To assess the utility of the tests for clinical use and seroepidemiologic studies, we examined the sensitivity of commercial antibody tests from Roche, Abbott, Novatec, Virotech Siemens, Euroimmun, and Mediagnost in a prospective diagnostic study. | 2020-07-15 |
| 32663827 | The keys to successfully managing pediatric AKI in a pandemic are flexible use of resources, good understanding of dialysis techniques, and teamwork. | 2020-07-15 |
| 32664179 | A nucleic acid test by rRT-PCR returned positive on a pharyngeal swab, confirming the diagnosis of COVID-19 pneumonia. […] The repeated chest CT scan plays an important role in the diagnosis and evaluation of the recovery of COVID-19. | 2020-07-16 |
| 32664423 |
|
2020-07-16 |
| 32664711 | Clinical symptoms and radiological findings of both viral pneumonia and lung adenocarcinoma may overlap resulting in diagnostic and clinical challenges.We present the case of a women admitted to our department presenting with an acute manifestation of coronavirus OC43 pneumonia with underlying undiagnosed lung adenocarcinoma. | 2020-07-16 |
| 32664761 | All patients presented with fever and low saturation levels at the diagnosis. […] One case was transferred after diagnosis to a tertiary referral center and delivered the day after for worsening clinical conditions. […] The swab could be helpful in diagnosis. | 2020-07-16 |
| 32664919 | Ninety-six percent (22/23) of patients developed antibodies to SARS-CoV-2 at a median of 32 days after initial diagnosis. | 2020-07-16 |
| 32665039 | This is a composite endpoint which includes positive results from any validated SARS-CoV-2 diagnostic assay including detection of viral RNA, and/or seroconversion. | 2020-07-16 |
| 32665041 | Phase I will consist of 5 self-paced online modules of 4-10 minutes each to learn the breath control techniques. | 2020-07-16 |
| 32665052 | The mean duration from admission to diagnosis was 2.2 ± 3.8 d (median: 1 d). […] The mean duration from diagnosis to death was 9.9 ± 7.0 d (median: 9 d). | 2020-07-16 |
| 32665331 | Apart from providing actionable information to public health authorities on the trend of the pandemic, the daily incidence reflects the process of disease in a susceptible population and thus reflects the pathogenesis of COVID-19, the public health response, and diagnosis and reporting. | 2020-07-16 |
| 32665420 | Serology assays should not be used for the diagnosis of acute infection but rather in carefully designed serosurveys to facilitate understanding of seroprevalence in a population and to identify previous exposure to SARS-CoV-2. | 2020-07-16 |
| 32665645 | Overall, this study presents a systemic view of the SARS-CoV-2 specific IgG and IgM responses and provides insights to aid the development of effective diagnostic, therapeutic and vaccination strategies. | 2020-07-16 |
| 32665887 | This rare case-report outlines the diagnosis, management and outcome of a sixty year old hypertensive and diabetic patient with serious COVID-19 pneumonia and underlying active TB. | 2020-07-16 |
| 32665888 | In this case, we emphasize the need for vigilance from frontline clinicians for timely diagnosis and appropriate clinical management of potential co-infections in the COVID era. | 2020-07-16 |
| 32665890 | Bedside echocardiography permitted prompt diagnosis and life-saving pericardiocentesis. […] Cardiac tamponade may complicate COVID-19 and should be included in the differential diagnosis of acute hemodynamic deterioration in mechanically ventilated COVID-19 patients. | 2020-07-16 |
| 32665932 | A diagnosis of pneumothorax and diffuse interstitial lung involvement was promptly made by lung ultrasound and confirmed by an HRCT scan. | 2020-07-16 |
| 32665933 | More data are required to elucidate how COVID-19 and thrombotic disease interact and so that preventive and early diagnosis strategies can be developed. […] Thrombotic disease as a complication of COVID-19 must be suspected by clinicians, and recognized and monitored by radiologists.Thrombosis is often the initial manifestation of SARS-CoV-2, hence the importance of early diagnosis to avoid complications and reduce morbidity and mortality. | 2020-07-16 |
| 32665934 | Blood gas analysis and lung ultrasound allowed the correct diagnosis to be reached. […] COVID-19 pneumonia is associated with cardiovascular complications and pulmonary embolisms.Lung ultrasound can aid diagnosis by visualizing small peripheral pulmonary embolisms. | 2020-07-16 |
| 32665936 | Very rarely, patients with extreme leukocytosis may develop spurious hypoxemia, or pseudohypoxemia, which confuses the diagnosis of complications and can lead to intervention errors. | 2020-07-16 |
| 32665941 | We report a transient Brugada-like ECG pattern without ongoing fever in a 57-year-old man, admitted with a diagnosis of COVID-19 pneumonia, who did not have syncope or a family history of sudden cardiac death. | 2020-07-16 |
| 32665963 | Then, we review the clinical symptoms, diagnosis, and treatment options of COVID-19 patients. | 2020-07-16 |
| 32665985 | Early diagnosis of SARS-CoV-2 infected patients is essential to control the dynamics of the COVID-19 pandemic. | 2020-07-16 |
| 32666026 | Based on the World Health Organization (WHO) International Classification of Functioning, Disability and Health (ICF) and its biopsychosocial model of functioning, we use the WHO Family of International Classifications (WHO-FICs) framework to form an expert consensus on the COVID-19 rehabilitation program, focusing on the diagnosis and evaluation of disease and functioning, and service delivery of rehabilitation, and to establish a standard rehabilitation framework, terminology system, and evaluation and intervention systems based the WHO-FICs. | 2020-07-16 |
| 32666093 | Literature indicates that TeleNP may offer reliable and valid assessments, but clinicians need to consider limitations, develop new informed consent procedures, report modifications of standard procedures, and state limitations to diagnostic conclusions and recommendations. | 2020-07-16 |
| 32666316 | To assess sensitivity/specificity of CT vs RT-PCR for the diagnosis of COVID-19 pneumonia in a prospective Italian cohort of symptomatic patients during the outbreak peak. | 2020-07-16 |
| 32666395 | While chest computed tomography (CT) plays an indispensable role in its diagnosis, the quantification and localization of lesions cannot be accurately assessed manually. | 2020-07-16 |
| 32666482 | We describe the adaptation of this Mobil’DNA lab to assist in Coronavirus SARS-CoV-2 diagnosis. | 2020-07-16 |
| 32667047 | However, we strongly believe that the existing evidence is enough to raise awareness among clinicians and help guide them through the diagnosis and optimal therapy of COVID-19 patients. | 2020-07-16 |
| 32667069 | Most adult thoracic patients were admitted from home, with a diagnosis of neoplastic disease in 60% of patients. | 2020-07-16 |
| 32667283 | Clinical manifestations and atypical radiographic features of COVID-19 led to the diagnosis of TB through positive interferon-gamma release assay and culture results. | 2020-07-16 |
| 32667391 | There are few data on the impact of COVID-19 in pregnancy, however, analyzing these data is important to guide the clinical practice, covering the early prevention, detection, patients’ isolation, epidemiological investigation, diagnosis and early treatment. | 2020-07-16 |
| 32667461 | First cases from Brazil, Rio de Janeiro, IBEx, and diagnosis team were reported in D36, D44, D66, and D74 respectively. | 2020-07-16 |
| 32667573 | Early diagnosis and timely case management is essential to reduce virus transmissibility. the research contributed to elucidate health and nursing actions in preventing and controlling neonatal infection by COVID-19. | 2020-07-16 |
| 32667583 | We propose a sequential battery of testing consisting of an epidemiologic survey, RT-PCR tests, serologic tests and chest CT on surgical candidates which may increase the negative predictive value, and facilitate surgical procedures. | 2020-07-16 |
| 32667665 | Notably, the two antiviral drugs have also previously been identified using molecular docking methods, and ribavirin is a recommended drug in the diagnosis and treatment protocol for COVID pneumonia (trial version 5-7) published by the National Health Commission of the P.R. of China. | 2020-07-16 |
| 32667716 | She rapidly worsened after COVID-19 diagnosis on 9th postoperative day. | 2020-07-16 |
| 32667839 | Conclusions: These tools can provide full neurological consultations, with the engagement of both patients and caregivers, and can support clinicians in defining whether patients need to access diagnostic and therapeutic procedures. | 2020-07-16 |
| 32668034 | This review was aimed to systematically evaluate the available literature on the impact of COVID-19 on cancer care and to critically analyze the diagnostic and therapeutic strategies suggested by various healthcare providers, societies, and institutions. | 2020-07-16 |
| 32668512 | Real-time reverse transcription polymerase chain reaction (RT-PCR) is currently the most commonly used method for the diagnosis of COVID-19 worldwide. […] The Korean Society for Laboratory Medicine and Korea Centers for Disease Prevention and Control regularly update the guidelines for COVID-19 diagnosis. […] Emergency use authorization for some laboratory diagnostic kits has been granted, enabling the timely diagnosis and treatment of COVID-19, and the isolation of infected patients. […] Here, we summarize the currently available laboratory tests for COVID-19 diagnosis. | 2020-07-16 |
| 32668514 | Current evidence supports lung ultrasound as a point-ofcare alternative diagnostic tool for various respiratory diseases. | 2020-07-16 |
| 32668515 | Herein, we report four confirmed coronavirus disease 2019 (COVID-19) cases in the early stage of the pandemic in South Korea and describe the identification, diagnosis, clinical course, and management, including one patient’s initial mild symptoms at presentation and their progression to pneumonia on day 21 of illness. | 2020-07-16 |
| 32668701 | We use state-of-the-art computer-aided drug design (CADD) techniques to identify prospective inhibitors of the main protease enzyme, 3CLpro of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19. | 2020-07-17 |
| 32668970 | Seven versions of the Diagnosis and Treatment Program for Coronavirus Disease-2019 successively issued by the Chinese government have designated traditional Chinese medicine (TCM) as a necessary medical strategy. […] Based on the changes in TCM diagnosis and treatment strategies in these seven versions of Diagnosis and Treatment Program for Coronavirus Disease-2019, this paper collected data reported by the Chinese government media; analyzed the understanding of the etiology, pathogenesis, syndrome differentiation, treatment methods, and prescriptions of COVID-19 by TCM and evaluated the clinical efficacy of TCM strategies. | 2020-07-17 |
| 32669014 | Results of laboratory tests, imaging tests, and nucleic acid tests on vaginal swabs for SARS-CoV-2 were also analyzed for pregnant women with a clinical diagnosis of COVID-19. | 2020-07-17 |
| 32669027 | After this case, we began to consider techniques that allow us to prevent the catheter from ending in the armpit, with benefit. | 2020-07-17 |
| 32669221 | The definition and diagnostic/management criteria of sepsis have been modified several times but the mortality rate has not been improved until date. | 2020-07-17 |
| 32670071 | Given the extreme importance of the current pandemic caused by COVID-19 and due to the fact that scientists agree that there is no identified treatment, this paper analyzes in detail the treatment of a severe COVID-19 patient with convalescent plasma and drugs based on current guidelines for COVID-19 diagnosis and treatment. | 2020-07-17 |
| 32670441 | Confirmed 2019-nCov-infected cases were identified in Dongyang and were treated according to guidelines for the diagnosis of 2019-nCov infection released by the National Health Commission. | 2020-07-17 |
| 32670522 | We report a severe case of COVID-19 in a patient with chronic lymphocytic leukemia and describe primarily the clinical presentation and the challenges encountered in the COVID-19 diagnosis, treatment, and specimens sampling pitfalls. […] This case highlights the importance of a comprehensive diagnostic approach of pneumonia in immunocompromised hosts, including timely and safe bronchoscopy, because of the broad differential diagnosis, more challenging with the current outbreak of COVID-19. | 2020-07-17 |
| 32670785 | Further, enhancing the capability of the COVID-19 diagnosis with the use of the chest imaging modalities is discussed. | 2020-07-17 |
| 32670925 | It includes the evidence-based information on epidemiological determinants (agent, host, and environment) of the disease, its clinical features, clinical and laboratory diagnosis, basic infection prevention and control measures, and clinical management of COVID-19 cases. | 2020-07-17 |
| 32670990 | We describe the clinical features and role of ultra-low-dose chest computed tomography (CT) and bronchoscopy in the diagnosis of coronavirus disease (COVID-19). […] Eventually, we confirmed the diagnosis using bronchoscopy and bronchoalveolar lavage (BAL). […] Clinical and laboratory findings in COVID-19 are unspecific.Chest CT has a diagnostic sensitivity comparable to nasopharyngeal swab RT-PCR assay but lacks specificity.RT-PCR assays on biological specimens, particularly nasopharyngeal swabs, are considered the diagnostic gold standard.Bronchoscopy and bronchoalveolar lavage can help confirm the diagnosis and should be performed in patients in whom diagnostic-driven treatment for COVID-19, such as tocilizumab or remdesivir, is being considered. | 2020-07-17 |
| 32671007 | The median duration of symptom onset to treatment was [1.0 (0.0-4.0) days], the duration of symptom onset to isolation [2.0 (0.0-6.0) days], and the duration of symptom onset to diagnosis [5.0 (2.0-8.0) days]. | 2020-07-17 |
| 32671013 | Verifying the presence of viral RNA is the gold standard for the diagnosis of COVID-19. […] However, RT-qPCR diagnosis often fails to catch infected patients, because of inconsistent swab sample collection. | 2020-07-17 |
| 32671086 | The most important test for the diagnosis is represented by RT-PCR, but, given the limited sensitivity, further radiological examinations are necessary. | 2020-07-17 |
| 32671350 | Through a 12-item descriptive questionnaire, ICU clinicians were assessed regarding preparedness, techniques employed to augment critical care capacity, and concerns related to caring for coronavirus disease 2019 patients. […] The majority (n = 4,010, 82.9%) identified that their hospital was employing techniques to augment critical care capacity. | 2020-07-17 |
| 32671354 | Data including patient demographics, primary diagnosis, age, body mass index, and duration of apnea time during the tracheostomy were collected. | 2020-07-17 |
| 32671537 | Background cross-reactivity with other coronaviruses may reduce the specificity of COVID-19 rapid serologic tests. […] We used stored 2018 serum samples from an existing pregnancy cohort study to evaluate the specificity of COVID-19 serologic rapid diagnostic tests. […] We used stored serum to evaluate four lateral flow rapid diagnostic tests, following manufacturers’ instructions. […] Blood specimens from sentinel prenatal clinics provide an opportunity to validate serologic tests with population-based samples. | 2020-07-17 |
| 32671890 | Dynamic monitoring of the concentration variation of IgM and IgG in patients with SARS-CoV-2 infections and exploring their diagnostic value for coronavirus disease-19 (COVID-19). […] The IgM cutoff value of 1.83 AU/mL for the diagnosis of COVID-19 was much better than the cutoff suggested by the manufacturer. | 2020-07-17 |
| 32672149 | Laboratory preparedness with quality-assured diagnostic assays is essential for controlling the current coronavirus disease (COVID-19) outbreak. […] To analyse SARS-CoV-2 testing performance, we used an online questionnaire developed for the European Union project RECOVER to assess molecular testing capacities in clinical diagnostic laboratories. | 2020-07-17 |
| 32672430 | Patients received, at the admission to the ED, a diagnostic work-up including: patient history, clinical examination, an arterial blood gas analysis (whenever possible performed on room air), laboratory blood tests, including serum concentrations of interleukin-6 (IL-6), lung ultrasound examination and a computed tomography (CT) scan of the thorax. | 2020-07-17 |
| 32672482 | Since frequent cardiovascular (CV) system involvement has soon been detected in patients occurring coronavirus disease 2019 (COVID-19), we would provide a simple review available to cardiologists who are going to be involved in the management of COVID-19 patients from several levels: from diagnosis to prevention and management of CV complications. | 2020-07-17 |
| 32672799 | Early diagnosis of coronavirus disease 2019 (COVID-19) and patient isolation are important for both individual patient care and disease containment. […] The diagnosis is confirmed by testing for the presence of nasopharyngeal viral RNA with a polymerase chain reaction assay, which has limited availability, variable turnaround time, and a high false-negative rate. […] To investigate the diagnostic and prognostic value of eosinopenia in COVID-19-positive patients. […] The absence of an eosinophil count in a CBC can aid in early diagnosis of COVID-19. | 2020-07-17 |
| 32673163 | The group reviewed literature, collated federal, regional and state regulations and information from insurers, and surveyed practitioners to identify best practices.Results: Literature indicates that TeleNP may offer reliable and valid assessments, but clinicians need to consider limitations, develop new informed consent procedures, report modifications of standard procedures, and state limitations to diagnostic conclusions and recommendations. | 2020-07-17 |
| 32673567 | To identify SARS-CoV-2-neutralizing antibodies, we analyzed the antibody response of 12 COVID-19 patients from 8 to 69 days after diagnosis. […] By screening 4,313 SARS-CoV-2-reactive B cells, we isolated 255 antibodies from different time points as early as 8 days after diagnosis. | 2020-07-17 |
| 32673577 | For tuberculosis, the greatest impact would be from reductions in timely diagnosis and treatment of new cases, which could result from any prolonged period of COVID-19 suppression interventions. | 2020-07-17 |
| 32673648 | Time of onset varied greatly, but diagnosis was more frequent in the first two weeks since in-hospital acceptance (73.8%). | 2020-07-17 |
| 32673837 | It is observed that the studies pertaining to virology, diagnosis and treatment, clinical features etc. have received highest citations than general studies on epidemiology or pandemic. | 2020-07-17 |
| 32673930 | We assessed COVID-19-related stress, self-isolation stressors, and coping in those with a primary anxiety-related disorder diagnosis, a primary mood disorder diagnosis, and no mental health disorder. […] Adults from a population-representative sample from the United States and Canada who reported current (past year) anxiety-related (n = 700) or mood (n = 368) disorders were compared to a random sample of respondents who did not report a current mental health diagnosis (n = 500) on COVID-19-related stress, self-isolation stress, and coping. | 2020-07-17 |
| 32674034 | Real-time reverse transcriptase polymerase chain reaction (rRTPCR) has been the main method for diagnosis of SARS-CoV-2 infection in the early stages of the COVID-19 pandemic. | 2020-07-17 |
| 32674170 | Discovering the characteristics of the pediatric COVID-19 disease is important for contributing to the diagnosis and treatment of the disease in this population. […] In this review, clinical characteristics, epidemiology, diagnosis, and management of pediatric COVID-19 pneumonia based on the recent literature are discussed. | 2020-07-17 |
| 32674479 | Through binomial logistic regression analysis, we identified a statistically significant prediction model for the presumptive diagnostic of some relevant clinical features of SARS-CoV-2 infection. | 2020-07-18 |
| 32674622 | New manufacturing techniques are emerging with the ability to address the challenges associated with the development of medical devices or diagnostics, during a pandemic. | 2020-07-18 |
| 32674696 | As a point-of-care immunodiagnostic test for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the serosurvey represents an alternative to the polymerase chain reaction (PCR) test to measure the magnitude of COVID-19 outbreak in the communities lacking sufficient diagnostic capability for PCR testing. | 2020-07-18 |
| 32674824 | A structured approach can help guide discussions regarding the diagnosis, expected course, and care of individuals with COVID-19 in long-term care settings. | 2020-07-18 |
| 32674856 | The COVID-19 epidemic has brought tremendous challenges to the diagnosis and treatment of such patients. […] To coordinate the diagnosis and treatment of infectious disease prevention and spine trauma so as to formulate a rigorous diagnosis and treatment plan and to reduce the disability and mortality of the disease, multidisciplinary collaboration is needed. | 2020-07-18 |
| 32675009 | Even in the current pandemic, we should not reduce our attention towards the diagnosis and treatment of GDM. […] The criteria for the diagnosis of overt diabetes are either fasting plasma glucose ≥126 mg/dL, or random plasma glucose ≥200 mg/dL, or glycated hemoglobin ≥6.5%. […] When the screening procedure (OGTT) cannot be safely performed, the diagnosis of GDM is acceptable if fasting plasma glucose is ≥ 92 mg/dL. […] In order to consider the impaired fasting glucose as an acceptable surrogate for the diagnosis of GDM, the fasting glucose measurement should be performed within the recommended time windows for the risk level (high or medium risk). | 2020-07-18 |
| 32675154 | We describe a case of an 82-year-old man who developed an anterior ST-elevation myocardial infarction (STEMI) and left ventricular thrombus while an inpatient following a diagnosis of severe COVID-19 infection (SARS-CoV-2). | 2020-07-18 |
| 32676052 | This may help with early diagnosis, prevention of disease spread, and treatment planning. […] Therefore, clinicians need to be vigilant in the diagnosis and treatment of these patients. | 2020-07-18 |
| 32676371 | This study aims to assess the diagnostic performance of CXR, with emphasis on its predictive value, for severe COVID-19 disease. […] Adjusting for key confounders of age and baseline Hb, CRSmax performed comparable to or better than laboratory markers in the diagnosis of severe disease. | 2020-07-18 |
| 32676372 | The recognition of the arch bridge sign may benefit patient care by earlier definitive diagnosis of COVID-19 pneumonia. | 2020-07-18 |
| 32676492 | Datasets were analyzed through a set of statistical techniques including principal component and hierarchical cluster analysis. | 2020-07-18 |
| 32676778 | Patient sex, age, mechanism of injury, associated injuries, fracture location, tobacco use, employment status, mental health diagnosis and presence of interpersonal violence were documented. | 2020-07-18 |
| 32677007 | On day 10, heparin treatment was replaced by danaparoid sodium, but by day 13, the continued low platelet count made a diagnosis of heparin-induced thrombocytopenia unlikely. | 2020-07-18 |
| 32677386 | The coronavirus disease (COVID-19) outbreak has reached global pandemic status as announced by the World Health Organization, which currently recommends reverse transcription polymerase chain reaction (RT-PCR) as the standard diagnostic tool. […] Although mobile cone-beam CT had some limitations regarding its image quality such as scatter noise, motion and streak artifacts, and limited field of view compared with conventional multi-detector CT, both cases had acceptable image quality to establish the diagnosis of COVID-19 pneumonia. | 2020-07-18 |
| 32677733 | To ascertain the diagnostic performance of FIT in symptomatic adult primary care patients. […] The diagnostic accuracy of FIT is reported by gender, age group and FIT threshold. | 2020-07-18 |
| 32677821 | The early, rapid, sensitive, and accurate diagnosis of viral infection provides rapid responses for public health surveillance, prevention, and control of contagious diffusion. […] More than 30% of the confirmed cases are asymptomatic, and the high false-negative rate (FNR) of a single assay requires the development of novel diagnostic techniques, combinative approaches, sampling from different locations, and consecutive detection. […] Diagnostic and therapeutic methods are evolving with a deeper understanding of virus pathology and the potential for relapse. […] In this Review, a comprehensive summary and comparison of different SARS-CoV-2 diagnostic methods are provided for researchers and clinicians to develop appropriate strategies for the timely and effective detection of SARS-CoV-2. […] The survey of current biosensors and diagnostic devices for viral nucleic acids, proteins, and particles and chest tomography will provide insight into the development of novel perspective techniques for the diagnosis of COVID-19. | 2020-07-18 |
| 32677858 | The objective of this preliminary report is to describe prehospital encounters for patients with a COVID-19 hospital diagnosis and/or COVID-19 EMS suspicion versus those with neither a hospital diagnosis nor EMS suspicion of the disease. […] Comparisons were stratified by COVID-19 hospital diagnosis and COVID-19 EMS suspicion. […] Of those, 814 (1%) patients had a COVID-19 hospital diagnosis. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32677909 | Real-time RT-PCR assays are recommended for diagnosis of COVID-19. […] A combination of patient’s exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. […] Repeat swab tests are helpful in diagnosis for this kind of patients. | 2020-07-18 |
| 32678173 | Recently, the diagnostic potential of VOCs has been realized, as correlations between the microbial VOC metabolome and specific bacterial pathogens have been identified. […] Finally, through VOC analysis, we illustrate a rapid non-invasive approach to the diagnosis of BALB/c mice infected with either F. tularensis SCHU S4 or Y. pestis CO92. | 2020-07-18 |
| 32678460 | We reviewed 37 published cases of GBS associated with COVID-19 to summarize this information for clinicians and to determine whether a specific clinical or electrodiagnostic (EDx) pattern is emerging. | 2020-07-18 |
| 32678526 | During their twice-weekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. | 2020-07-18 |
| 32678809 | The recommendations were the following: unrestricted use of personal protection elements, use of extraoral radiographic techniques, use of mouth rinses with 1% hydrogen peroxide or 0.2% iodine povidone, a four-hand technique with ongoing aspiration and the use of absorbable sutures. | 2020-07-18 |
| 32678948 | COVID-19 diagnosis coincided with a new diagnosis of a haematological malignancy in four patients. […] Among patients, 82% were on systemic anti-cancer therapy (SACT) at the time of COVID-19 diagnosis. […] Raised C-reactive protein at diagnosis predicted an aggressive clinical course. | 2020-07-18 |
| 32679081 | In this prospective surveillance study, we set up rapid SARS-CoV-2 nanopore sequencing from PCR-positive diagnostic samples collected from our hospital (Cambridge, UK) and a random selection from hospitals in the East of England, enabling sample-to-sequence in less than 24 h. | 2020-07-18 |
| 32679298 | We evaluated the diagnostic performance of the Abbott ARCHITECT SARS-CoV-2 IgG test, a fully automated indirect immunoassay that detects antibodies directed to a recombinant SARS-CoV-2 Nucleocapsid antigen. […] This finding supports the use of this automated serological assay in diagnostic algorithm and public health intervention, especially for high loads of testing. | 2020-07-18 |
| 32679347 | All four patients had elevated blood pressure and renal injury in the days preceding PRES diagnosis, as well as evidence of systemic inflammation and systemic hypercoagulability. | 2020-07-18 |
| 32679582 | Since data regarding the epidemiologic and clinical characteristics in neonates and children developing coronavirus disease 2019 (COVID-19) are scarce and originate mainly from one country (China), we reviewed all the current literature from 1 December 2019 to 7 May 2020 to provide useful information about SARS-CoV2 viral biology, epidemiology, diagnosis, clinical features, treatment, prevention, and hospital organization for clinicians dealing with this selected population. | 2020-07-18 |
| 32679910 | The great majority of patients (80%) developed SARS-CoV-2 IgG at three weeks after symptoms’ onset while the detectability of SARS-CoV-2 RNA dramatically decreased over time, suggesting the crucial role of combination of molecular and serological assays for the diagnosis of COVID-19 in those patients reporting mild symptoms. | 2020-07-19 |
| 32680592 | Diagnosis of COVID-19 was confirmed by polymerase chain reaction to SARS-CoV-2 in 92 (92.5%). | 2020-07-19 |
| 32680659 | The confinement of the population, researchers, shows the need to adapt the qualitative methodology, techniques and tools, to the current context generated by COVID-19. […] Currently, we are working on techniques and models of good practice in this area. […] This note includes data collection tools used in qualitative research in health sciences, a selection of techniques for qualitative online research is made, and 10 rules for the design of an e-research of this type are provided. | 2020-07-19 |
| 32680715 | The higher positivity rates among symptomatic professionals working outside the hospital compared to those working in hospital may be explained in part by a shortage of protective equipment and by difficulties in accessing virological diagnosis, which were greater outside the hospital when the epidemic began. | 2020-07-19 |
| 32680910 | Biopsy diagnosis informed treatment and prognosis in all patients. | 2020-07-19 |
| 32681166 | However, clinicopathologic features diagnostic of hemophagocytic lymphohistiocytosis (HLH) have not been reported. […] One patient showed diagnostic features of HLH with an H-score of 217, while a second patient likely had HLH with a partial H-score of 145 due to a missing triglyceride level. | 2020-07-19 |
| 32681280 | The failure to appreciate the characteristics and limitations of the diagnostic tests may lead to disastrous consequences for the patient and the multidisciplinary team looking after them. | 2020-07-19 |
| 32681308 | We developed a chemiluminescence immunoassay method based on the recombinant nucleocapsid antigen and assessed its performance for the clinical diagnosis of severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infections by detecting SARS-CoV-2-specific IgM and IgG antibodies in patients. […] Plasmas from 29 healthy cohorts, 51 tuberculosis patients, and 79 confirmed SARS-CoV-2 patients were employed to evaluate the chemiluminescence immunoassay method performance for the clinical diagnosis of SARS-CoV-2 infections. […] The developed high sensitivity and specificity chemiluminescence immunoassay IgG testing method combined with the RT-PCR approach can improve the clinical diagnosis for SARS-CoV-2 infections and thus contribute to the control of COVID-19 expansion. | 2020-07-19 |
| 32681309 | Diagnosis of COVID is performed by PCR methods, but their capacity is limited by the requirement of high-level facilities and instruments. […] The prevalence of PCR-confirmed COVID diagnosis was 43.1%. | 2020-07-19 |
| 32681447 | The laboratory diagnosis is typically based on serological or molecular methods. […] This paper will cover epidemiology, taxonomy, pathogenesis, clinical signs, diagnosis, therapy, economic impact and prevention of coronavirus infections in cattle. | 2020-07-19 |
| 32681559 | To determine the diagnostic value of hematologic markers for coronavirus disease 2019 (COVID-19) and explore their relationship with disease severity. […] Receiver operating characteristic (ROC) curves were used to study the accuracy of the various diagnostic tests. […] ROC curve analysis revealed that MLR had a high diagnostic value in differentiating COVID-19 patients from healthy subjects, but not from IP patients. […] Lymphocyte count was lower in the ARDS group and yielded a higher diagnostic value than the other variables. […] Lymphocyte count may be useful to establish the early diagnosis of ARDS in the COVID-19 patients. | 2020-07-19 |
| 32681674 | Original studies providing information on clinical digestive symptoms or biomarkers of liver function in patients with polymerase chain reaction confirmed diagnosis of COVID-19 were included. | 2020-07-19 |
| 32681752 | The aim of our study is to analyze the impact of the lockdown on the number, type, and severity of Dermatological ED diagnosis. […] Some diagnostic categories showed a significant difference with a higher incidence of vasculopathic lesions (0.6% vs 12.1%, P < .0001), urticarial rashes (8.5% vs 21.2%, P = .03), and scabies (3% vs 12.1%, P = .023). | 2020-07-19 |
| 32681756 | All kidney transplant recipients who referred to the Razi Hospital of Rasht with a diagnosis of SARS-CoV-2 infection from February 20 to 19th of April 2020 have been included in this observational study. | 2020-07-19 |
| 32681783 | Nine cases with COVID-19 diagnosis before admission were excluded. | 2020-07-19 |
| 32681847 | Finally, we take a practical approach in describing how we use the three techniques, including the common indications, contraindications, and practical aspects of application. | 2020-07-19 |
| 32681933 | The aim of this study was to systematically and comprehensively evaluate the diagnostic and prognostic value of myocardial injury biomarkers in COVID-19 patients. | 2020-07-19 |
| 32681950 | The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in the field and for delivering targeted therapeutics. | 2020-07-19 |
| 32681968 | Therefore, the prevention of COVID-19 and the rapid diagnosis of infected patients is crucial. | 2020-07-19 |
| 32682004 | To determine the incidence of PE in hospitalised patients with COVID-19 and the diagnostic yield of Computer Tomography Pulmonary Angiography (CTPA) for PE. […] We also examined the utility of D-dimer and conventional pre-test probability for diagnosis of PE in COVID-19. […] The diagnostic yield for PE was 37%. […] More data are needed to identify an optimal diagnostic pathway in patients with COVID-19. | 2020-07-19 |
| 32682217 | To beat the pandemic, Brazil needs to optimize the COVID-19 diagnosis through the SARS-CoV-2 identification using RT-PCR tests and adjust its policies to save lives. […] However, as widely announced, in Brazil the diagnosis using RT-PCR is still scarce and part of the material collected from COVID-19 patients was disposed of and many patients were not tested, regardless of the seriousness of the symptoms, due to errors of medical data records, improper conservation of the samples after collection and/or during transport, which compromised the quality of the material to be tested. | 2020-07-19 |
| 32682342 | Positive diagnosis was made on a real-time polymerase chain reaction (RT-PCR) assay of a nasopharyngeal and oropharyngeal specimen. […] Of them, 29 had the diagnosis confirmed by RT-PCR. | 2020-07-19 |
| 32682452 | The patient tested negative by reverse transcription polymerase chain reaction (RT-PCR) of nasopharyngeal swab, yet positive for IgG and IgM by ELISA, suggesting COVID-19 diagnosis. | 2020-07-20 |
| 32682460 | Mental health concerns have been addressed via the public mental health response and by adapting mental health services, mostly focusing on infection control, modifying access to diagnosis and treatment, ensuring continuity of care for mental health service users, and paying attention to new cases of mental ill health and populations at high risk of mental health problems. | 2020-07-20 |
| 32682487 | We evaluated the impact of timeliness and completeness in various steps of a contact tracing strategy using a stochastic mathematical model with explicit time delays between time of infection and symptom onset, and between symptom onset, diagnosis by testing, and isolation (testing delay). | 2020-07-20 |
| 32682745 | We aimed to characterize recent COVID-19-related community practice noninvasive diagnostic imaging professional work declines. […] Using imaging metadata from nine community radiology practices across the United States between January 2019 and May 2020, we mapped work relative value unit (wRVU)-weighted stand-alone noninvasive diagnostic imaging service codes to both modality and body region. […] Substantial COVID-19-related diagnostic imaging work declines were similar across community practices and disproportionately impacted mammography. | 2020-07-20 |
| 32683296 | Some studies have employed several techniques to facilitate the combination of the immunoinformatics approach and comparative genomic approach in order to determine the potential peptides for designing the T-cell epitope-based peptide vaccine using the 2019-nCoV envelope protein as a target. | 2020-07-20 |
| 32683343 | Fifty-three were excluded from the diagnosis of COVID-19. […] The clinical features of the confirmed patients with COVID-19 were insufficient for early diagnosis of COVID-19. […] The epidemiologic history was of great significance in the early diagnosis of COVID-19. […] More sensitive diagnostic methods are needed to aid the differential diagnosis of suspected patients with COVID-19. | 2020-07-20 |
| 32683550 | The assessments were compared with patient status of diagnosis reports and key phrases extracted from radiology reports using the area under the receiver operating characteristic curve (AUC) and Cohen’s kappa, respectively. | 2020-07-20 |
| 32683639 | The purpose of our study was to identify differences in the clinical characteristics and the in-hospital mortality of patients with a laboratory-confirmed diagnosis of COVID-19 internationally. […] A comprehensive search of all published literature on adult patients with laboratory-confirmed diagnosis of COVID-19 that reported on the clinical characteristics and in-hospital mortality was performed. | 2020-07-20 |
| 32683857 | Herein, we demonstrate a novel diagnosis approach for label-free identification and structural characterization of individual viruses that is based on a combination of nanoscale Raman and infrared spectroscopy. | 2020-07-21 |
| 32683882 | The study was performed on patients with real-time polymerase chain reaction and computed tomography lung diagnosis. | 2020-07-21 |
| 32684101 | Monitoring NLR, T lymphocytes, and subsets would help physicians with the proper diagnosis and treatment of COVID-19. | 2020-07-21 |
| 32684109 | Thus, we systematically applied the computational techniques to identify the plausible inhibitor from a chosen set of well characterized diaryl pyrimidine analogues which may disrupt interfacial interaction of spike glycoprotein (S) at the surface of hACE2. | 2020-07-21 |
| 32684122 | Diagnosis of BrS in patients currently relies on presentation with a type-1 Brugada pattern on ECG either spontaneously or following a drug provocation test using a sodium channel blocker. […] In this review, we summarise the current knowledge on the epidemiology, pathophysiology, genetics, clinical diagnosis, risk stratification and treatment of patients with BrS, with special emphasis on COVID-19 comorbidity. | 2020-07-21 |
| 32684145 | Median time from onset of COVID symptoms to stroke diagnosis was 21 days. | 2020-07-21 |
| 32684166 | Due to a lack of data, no consensus has been reached about the best practices for the diagnosis and treatment of cancer patients. | 2020-07-21 |
| 32684205 | As the ability of treating coronavirus disease 2019 (COVID-19) improves, the theory and method of diagnosis and treatment of COVID-19 need to be further enriched and perfected. […] Xuebijing injection, which was developed based on “three syndromes and three methods”, has been repeatedly recommended in the national diagnosis and treatment guidelines. […] In order to facilitate the clinical practitioners better understanding the “three syndromes and three methods”, and apply the theory into the treatment of COVID-19, Expert opinion on diagnosis and treatment of coronavirus disease 2019 with traditional Chinese medicine based on “three syndromes and three methods” was organized by experts from China Association of Integrative Medicine Emergency Medicine Committee, which could make references for clinical practice. | 2020-07-21 |
| 32684210 | The Chinese keyword co-occurrence, clustering and highlighted words analysis showed that the main research areas of severe COVID-19 included clinical features, traditional Chinese medicine treatment, medical imaging, integrated traditional Chinese and Western medicine treatment and so on; nucleic acid detection, clinical features and diagnosis, plague theory and etiology mechanism, traditional Chinese medicine and integrated Chinese and Western medicine treatment, severe COVID-19 combined with diabetes and prognosis research will become future research trends; keyword cluster analysis showed that severe COVID-19, combined chronic underlying diseases, CT imaging characteristics will also become new trends in the field of research. […] Domestic research focuses on the diagnosis and treatment of severe cases, while foreign countries attach importance to epidemic response and prevention. | 2020-07-21 |
| 32684225 | With reference to the customs inspection and quarantine regulations, in accordance with the Diagnosis and treatment of pneumonia caused by novel coronavirus (trial version 3) for mulated by the National Health Commission of the People’s Republic of China and the Novel coronavirus infected pneumonia port control and technology plan (first version) formulated by the General Administration of Customs, combined with the actual situation of cruise ships, the medical investigation team developed the inspection standards, including door-to-door inspections, temperature measurement and epidemiological investigations on all persons on board of the cruise ship. | 2020-07-21 |
| 32684340 | Clinical applicability of rapid diagnostic test kit for SARS-CoV-2 antibodies was evaluated. | 2020-07-21 |
| 32684717 | For each centre, we reported the number, diagnosis, co-morbidities, treatment, hospital course, complications and outcomes of confirmed COVID 19 patients. | 2020-07-21 |
| 32684752 | During the epidemic of COVID-19, the emergency response plan for the NICU should be based on the actual situation, including diagnosis, isolation, and treatment, as well as available equipment and staffing, and take into account the psychosocial needs of the families and neonatal care staff. | 2020-07-21 |
| 32685022 | At present, various diagnostic kits to test for SARS-CoV-2 are available for use to initiate appropriate treatment faster and to limit further spread of the virus. | 2020-07-21 |
| 32685076 | Nevertheless considering the broad differential diagnosis of acute myelitis, prompt clinical, and diagnostic work up was crucial to exclude other causes. […] Patients presenting with neurological symptoms such as loss of consciousness, ataxia, convulsions, status epilepticus, encephalitis, myelitis or neuritis should raise concerns for COVID-19 infection during this pandemic prompting early diagnosis and initiation of proper management. | 2020-07-21 |
| 32685080 | Currently, positive of virus nucleic acid in respiratory or blood samples is the gold standard for the diagnosis of the disease, but the nucleic acid test may be false negative. […] Chest CT examination plays an important role in diagnosis of COVID-19 pneumonia. […] Chest CT examination may be helpful for diagnosis of COVID-19 pneumonia. | 2020-07-21 |
| 32685081 | Hospitals, in particular diagnostic imaging services, should prepare accordingly in regard to health precautions while keeping in mind the potential discrepancies between clinical presentation and resultant radiologic patterns. | 2020-07-21 |
| 32685124 | Timely diagnosis is a problem as there is no single test that can achieve the highest acceptable sensitivity. | 2020-07-21 |
| 32685170 | This “andrological bias”, if proven, must be reduced by specific andrological diagnosis, therapeutic and prophylactic measures. | 2020-07-21 |
| 32685326 | Even though our patient did not develop acute respiratory distress syndrome or further complications, the presented case highlights the importance of basic radiological monitoring of the disease in order to ensure prompt diagnosis of complications and appropriate subsequent management. | 2020-07-21 |
| 32685435 | Laboratory diagnosis through RT-PCR testing alone lacks adequate sensitivity to be recommended as the only valid criterion to confirm COVID-19 diagnosis. https://bit.ly/2BLFnEe. | 2020-07-21 |
| 32685653 | The COVID-19 pandemic has necessitated increased use of telemedicine for diagnosis and management of musculoskeletal disorders. […] Definitive diagnosis and treatment occurred only after completion of the impending fracture. | 2020-07-21 |
| 32685880 | This forum discusses the lungs as the epicenter for the hemostatic issues, puts forward a proposal for staging COVID-19 coagulopathy based on available diagnostic markers, and suggest considering current and future treatment options based on these different stages. | 2020-07-21 |
| 32685892 | In this single-center study, we explored all diagnostic imaging tests performed for suspected PE between weeks 1 and 17 of the years 2018, 2019, and 2020. […] Compared to weeks 1 to 11, 2020, an abrupt decline in PE diagnosis (mean weekly rate, 5.2; 95% confidence interval [CI], 3.8-6.6 vs 1.8; 95% CI, 0.0-3.6) and imaging tests (mean weekly rate, 32.5; 95% CI, 27.5-37.6 vs. […] Our study demonstrates that the COVID-19 pandemic has an impact on non-COVID-19-related acute diseases as shown by the decline in incidence of PE and imaging procedures for diagnostic workup. | 2020-07-21 |
| 32685893 | Currently, there is great interest to assess venous thrombosis prevalence, diagnosis, prevention, and management in patients with COVID-19. | 2020-07-21 |
| 32686287 | During COVID-19 pandemic, 16.5% of responders continued face-to-face consultation while most changed to telephone (32%) or video (18%) consultations. 19% reported a shortage of medical supplies. 22% reported a delay in diagnosis of patients with new-onset diabetes, while 15% reported a higher incidence of DKA. 12% reported having one or more patients with COVID-19. […] One fourth of HCP reported delays in diagnosis and an increased rate of DKA. | 2020-07-21 |
| 32686375 | The patient was discharged 105 days after the COVID-19 diagnosis. | 2020-07-21 |
| 32686780 | A gender-based approach to clinical practice also in the context of this pandemic seems to be mandatory, as it could significantly contribute to health promotion by improving the effectiveness of diagnostic and/or therapeutic approaches and, therefore, leading to important benefits primarily for the patients but also for the sustainability of the National Health System. | 2020-07-21 |
| 32686899 | There were 362 patients (2.6% of all) with COVID-19 confirmed/suspected who were treated in interventional cardiology centers and 145 with ST-Elevation Myocardial Infarction (STEMI) diagnosis (6% of all STEMIs). | 2020-07-21 |
| 32687455 | Radiology departments play a critical role in policy and guideline development both for the department and for the institutions, specifically in planning diagnostic screening, triage, and management of patients. | 2020-07-21 |
| 32687484 | A key explanation for the inability to address this controversy has been the lack of diagnostic tools to evaluate immune function in COVID-19 infections. | 2020-07-21 |
| 32687805 | Yet the scarcity of knowledge on the dynamics of the immune response to infection has led to hesitation on recommending the use of rapid immunodiagnostic tests, even though rapid serology tests are commercially available and scalable. | 2020-07-21 |
| 32688395 | Median age at COVID-19 diagnosis was 70.5 years. […] Ninety patients (45%) were receiving active CLL therapy at COVID-19 diagnosis, most commonly Bruton tyrosine kinase inhibitors (BTKi’s; n = 68/90 [76%]). […] CLL-directed treatment with BTKi’s at COVID-19 diagnosis did not impact survival (case fatality rate, 34% vs 35%), though the BTKi was held during the COVID-19 course for most patients. | 2020-07-21 |
| 32689711 | The detection and diagnosis have been improved, as well. | 2020-07-22 |
| 32689813 | This study reports the successful experience of diagnosis and treatment of an older patient with COVID-19 accompanied by progressive renal impairment, and pertinent literature was reviewed to help clinicians raise awareness of the disease. | 2020-07-22 |
| 32690096 | This review is intended to summarize the research on this new coronavirus, to analyze the similarities and differences between COVID-19 and previous outbreaks of severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) and to provide guidance regarding new methods of prevention, diagnosis and clinical treatment based on autodock simulations. […] We also found that the types and severity of clinical symptoms vary, which means that the diagnosis and nursing measures also require differentiation. | 2020-07-22 |
| 32690307 | Serologic tests showed a serum angiotensin-converting enzyme level of 58 nmol/mL/min. […] The bronchoalveolar lavage findings provided an accurate sarcoidosis diagnosis, and a high-resolution computed tomographic scan revealed stage 1 pulmonary involvement. | 2020-07-22 |
| 32690444 | However, the majority of patients with COVID-19 in this age cohort had atypical symptoms, and early diagnosis depends on prompt use of a viral nucleic acid test. | 2020-07-22 |
| 32690602 | This reduced capacity, along with public reluctance to undergo endoscopy during the pandemic, might result in excess mortality from delayed cancer diagnosis. […] Using the UK’s National Endoscopy Database (NED), we performed the first national analysis of the impact of the pandemic on endoscopy services and endoscopic cancer diagnosis. | 2020-07-22 |
| 32690987 | By discussing the diagnostic rationale and reviewing the relevant literature we hope to advance the existing understanding of this disease and its effects on the musculoskeletal system. | 2020-07-22 |
| 32691004 | As the cases of COVID-19 are flooding around the world, atypical presentations are being recognized, making the diagnosis challenging. | 2020-07-22 |
| 32691024 | In this review we summarize the most up to date literature around the association between COVID-19 and myocarditis and provide clinicians a practical framework about the clinical manifestations, diagnostic tools, and treatment options currently available. | 2020-07-22 |
| 32691128 | This delay in diagnosis and management of surgical disease could result in significant mortality and morbidity among the most vulnerable population-the children. | 2020-07-22 |
| 32691211 | We aimed to investigate the diagnostic performance of chest CT compared with first RT-PCR results in adult patients suspected of COVID-19 infection in an ED setting. […] We also constructed a predictive machine learning model based on chest CT and additional data to improve the diagnostic accuracy of chest CT. […] With first RT-PCR as reference standard, the diagnostic performance of chest CT using the CO-RADS score was assessed. […] Chest CT, using the CO-RADS scoring system, is a sensitive and specific method that can aid in the diagnosis of COVID-19, especially if RT-PCR tests are scarce during an outbreak. […] Combining a predictive machine learning model could further improve the accuracy of diagnostic chest CT for COVID-19. | 2020-07-22 |
| 32691641 | This study aimed to present the prevalence of overall and asymptomatic SARS-CoV-2 infection rates in pregnant women admitted to the hospital, and assess the diagnostic accuracy of maternal symptoms and lung ultrasound (LUS) findings in detecting the infection. […] On a secondary diagnostic performance analysis, the positive predictive value and the sensitivity were found as 44% and 47.8% for the triage based on maternal symptoms and, 82.3% and 60.9% for the triage based on LUS, respectively. | 2020-07-22 |
| 32691697 | With restricted access to wet laboratory techniques, an alternative approach is to engage in computational screening of lead molecules that could inhibit SARS-CoV-2 at different stages of its infectious cycle. | 2020-07-22 |
| 32691863 | To validate the diagnostic accuracy of the Augurix SARS-CoV-2 IgM/IgG rapid immunoassay diagnostic test (RDT) for COVID-19. […] Diagnostic accuracy of the IgG RDT was assessed against both an in-house recombinant spike-expressing immunofluorescence assay (rIFA), as an established reference method (primary endpoint), and the Euroimmun SARS-CoV-2 IgG enzyme-linked immunosorbent assays (ELISA) (secondary endpoint). […] When considering samples taken >14 days after RT-PCR diagnosis, NPV was 100% (95%CI:90-100), and PPV was 100% (95%CI:72-100). […] The Augurix IgG-RDT done in whole blood displays a high diagnostic accuracy for SARS-CoV-2 IgG in high COVID-19 prevalence settings, where its use could be considered in the absence of routine diagnostic serology facilities. | 2020-07-22 |
| 32691919 | The nucleic acid test (NAT) of COVID-19 currently was the most reliable established laboratory diagnosis method in clinical. | 2020-07-22 |
| 32692001 | The primary objective was to describe the clinical characteristics and 30-day mortality rates in emergency department patients with coronavirus disease 2019 (COVID-19) in different diagnostic groupings. […] COVID-19 diagnostic groups differ according to clinical and laboratory characteristics, and the differences are associated with the 30-day prognosis. | 2020-07-22 |
| 32692238 | This case highlighted the importance of close coordination between Chinese medicine and western medicine in the diagnosis and treatment, as well as the need for rapid dissemination of clinical information related to patient care with this emerging infection. […] We reported a COVID-19 case confirmed in China and described the identification, diagnosis, clinical course, and management of the case. […] Our study was the first time tongue diagnosis was applied in time series analysis of the progression of COVID-19 disease. […] Based on this success, we will further apply tongue diagnosis to tongue characteristics of COVID-19 patients to help limit the risk of COVID-19. | 2020-07-22 |
| 32692241 | According to the fifth and sixth editions of the new coronavirus pneumonia diagnosis and treatment plan issued by the National Health Commission of the People’s Republic of China and National Administration of Traditional Chinese Medicine, we carried out the case analysis and infectious disease investigation and research on the confirmed and suspected cases of new coronavirus pneumonia admitted to the second-floor ward of the hospital from January 28th, 2020, to February 26th, 2020. […] The average time from onset to diagnosis was 5.38 days. | 2020-07-22 |
| 32692248 | Aim: In this study, the roles of biomarkers from a peripheral blood sample in the diagnosis of COVID-19 patients who have visited the emergency room have been evaluated. […] Conclusion: Leukocyte, neutrophil, platelet count, NLR and SII values can be used in the diagnosis of COVID-19. | 2020-07-22 |
| 32692666 | Using two LAMP primer sets, the ORF1ab (opening reading frame 1a/b) and N (nucleoprotein) genes of SARS-CoV-2 were simultaneously amplified in a single-tube reaction, and detected with the diagnosis results easily interpreted by LFB. […] The total diagnostic test can be completed within 1 h from sample collection to result interpretation. | 2020-07-22 |
| 32692733 | CASE REPORT A 53-year old patient was admitted with symptoms and diagnostic findings consistent with AIP. […] Thorough etiological workup revealed an elevated IgG4 level of 361 mg/dL and significant clinical response to corticosteroid treatment, leading to a diagnosis of AIP. | 2020-07-22 |
| 32692769 | LUSS helped with the diagnosis of ventilator-associated pneumonia (VAP), showing an increased score and the presence of new lung consolidations in all 5 patients with VAPs. […] It might help with early VAP diagnosis, mechanical ventilation weaning management, and potentially reduce the need for X-ray and CT exams. | 2020-07-22 |
| 32692877 | Although there is a clear association with elevated D-dimer and severity of COVID-19 disease, it is important to highlight the fact that D-dimer has always been utilised in conjunction with clinical pre-test probability, as a predictive tool to help exclude a possible diagnosis of venous thromboembolism. | 2020-07-22 |
| 32693757 | Present analysis showed that key areas of the inventions have been focused on vaccines and diagnostic kits apart from the composition for treatment of CoV. […] We also observed that no specific vaccine treatments is available for treatment of 2019-nCov, however, developing novel chemical or biological drugs and kits for early diagnosis, prevention and disease management is the primarily governing topic among the patented inventions. […] Further, the findings and outcome of the present study offer insights for the proposed research and innovation opportunities and provide actionable information in order to facilitate policymakers, academia, research driven institutes and also investors to make better decisions regarding programmed steps for research and development for the diagnosis, treatment and taking preventive measures for CoV and 2019-nCoV. | 2020-07-23 |
| 32694268 | With medical imaging analysis, pixel-annotated distinguishable features on COVID-19 patients may help with noninvasive diagnosis and severity outcome predictions. | 2020-07-23 |
| 32694270 | In cases where more complex diagnostic tools are warranted, a model incorporating telemedicine and focused in-person visits may still be beneficial. | 2020-07-23 |
| 32694481 | Daily generated variables representing an overall grade for distancing, changes in distances traveled, encounters between individuals, and daily visitation, were modeled as predictors of average R value for the following week, using linear regression techniques for 8 counties surrounding the city of Syracuse, New York. | 2020-07-23 |
| 32695321 | The diagnosis and treatment of PD patients with COVID-19 are discussed. | 2020-07-23 |
| 32695323 | Of the nine survivors, eight still tested positive for SARS-CoV-2 a median of 19 days (IQR 9.25-23) after diagnosis. […] Six patients died (case fatality rate 40%) a median of 5.5 days (IQR 1.75-9.75) after diagnosis. | 2020-07-23 |
| 32695325 | Despite our use of sensitive reverse transcription polymerase chain reaction techniques in this study, we failed to detect the virus in blood, urine and kidney tissues. | 2020-07-23 |
| 32695551 | Coronavirus disease 2019 (COVID-19) is a novel infectious viral disease, which lacks well-established diagnostic laboratory parameters that could be used to evaluate disease severity, thromboembolism or cardiovascular events and to predict clinical prognosis. | 2020-07-23 |
| 32695683 | An interesting finding regarding eosinopenia that can have both diagnostic and prognostic value is reported by some authors. | 2020-07-23 |
| 32695791 | Background: The unprecedented impact of the COVID-19 pandemic on modern society has ignited a “gold rush” for effective treatment and diagnostic strategies, with a significant diversion of economic, scientific, and human resources toward dedicated clinical research. | 2020-07-23 |
| 32696013 | As the severe acute respiratory syndrome-coronavirus-2 pandemic develops, assays to detect the virus and infection caused by it are needed for diagnosis and management. […] Nucleic acid assays such as quantitative, or real-time, polymerase chain reaction and loop-mediated isothermal amplification are ideal for acute diagnosis with polymerase chain reaction testing remaining the “gold standard” to diagnose acute infection by severe acute respiratory syndrome-coronavirus-2, specifically the presence of viral RNA. | 2020-07-23 |
| 32696088 | Briefly, in phase 1, EEG was recommended only for those acute/subacute neurological symptoms where EEG is necessary for diagnosis, prognosis, or therapy. […] During the different phases of COVID-19 pandemic, the EEG should be reserved for patients really benefiting from its execution in terms of diagnosis, treatment, prognosis, and avoidance of emergency room access. | 2020-07-23 |
| 32696734 | Individuals with psychiatric disorders were overrepresented among the 1474 UK Biobank participants with test data: 23% of the COVID-19 test sample had a psychiatric diagnosis compared with 10% in the full cohort (P < 0.0001). | 2020-07-23 |
| 32696830 | We performed a systematic review and meta-analysis to analyze whether COVID-19 in pregnant women is related to premature birth and birth weight, and to summarize the diagnostic results of neonates born to mothers with COVID-19 for investigating the possibility of vertical transmission. | 2020-07-23 |
| 32696861 | OBJECTIVE The present study aimed to investigate the role of neutrophil/lymphocyte ratio (NLR), an inflammation marker, complete blood count, and biochemical parameters in the diagnosis of COVID-19. […] CONCLUSION NLR is an independent predictor for the diagnosis of COVID-19. […] We also found that fever and total bilirubin measurements could be useful for the diagnosis of COVID-19 in this population. | 2020-07-23 |
| 32696883 | RESULTS Anticoagulation therapy can be started following the DIC diagnosis in Covid-19 patients despite the bleeding risks. | 2020-07-23 |
| 32696908 | Dentists can be first line of diagnosis of the disease, as they work in close contact with patients and are at the risk of being affected by COVID-19 and all respiratory infections. | 2020-07-23 |
| 32697005 | Many articles have been published regarding to the spread of the virus and the role that saliva plays in its transmission and diagnosis. | 2020-07-23 |
| 32697060 | Health authorities should frame polices that can support TB patients by providing diagnostic, management and prevention services without any interruption during this era of ongoing COVID-19 pandemic. | 2020-07-23 |
| 32697082 | These results pave the way for the development of time-efficient viral diagnostic tests based on mass spectrometry. | 2020-07-23 |
| 32697482 | ICU of a university-affiliated hospital from northern Italy dedicated to care of patients with confirmed diagnosis of coronavirus disease 2019. […] Ten intubated patients with acute respiratory distress syndrome and confirmed diagnosis of coronavirus disease 2019. | 2020-07-23 |
| 32698320 | The early diagnosis of COVID-19 in health care workers, must consider, in addition to respiratory disorders and fever, anosmia, dysgeusia, exhaustion, myalgias and enteric disorders. | 2020-07-24 |
| 32698479 | Considering the global healthcare urgency, several techniques, including whole genome sequencing and computed tomography imaging have been employed for diagnosing infected people. […] Detection based on non-contact optical techniques is very helpful in managing the spread of the virus, and to aid in the disinfection of surfaces. […] In addition, all the different techniques are critically analyzed, compared, and contrasted to identify the most promising methods. […] Moreover, promising research ideas for high accuracy of detection in trace concentrations, via color change and light-sensitive nanostructures, to assist fingerprint techniques (to identify the virus at the contact surface of the gas and solid phase) are also presented. | 2020-07-24 |
| 32698669 | There was no instance of failed acquisition, nondiagnostic examination, or suggestion of repetition in both groups. […] Our initial clinical experience suggests that the acquisition of portable chest radiographs through the glass doors of isolation rooms is technically feasible and results in diagnostic quality studies. | 2020-07-24 |
| 32698732 | Considering the possibility of neurological involvement in patients with SARS-CoV-2 infection can result in earlier diagnosis and treatment; otherwise permanent, irreversible sequelae and even death may follow. | 2020-07-24 |
| 32698862 | At present, the diagnosis of coronavirus disease 2019 (COVID-19) is made through a nasopharyngeal swab based on reverse transcription polymerase chain reaction (RT-PCR) technique. […] The purpose of this scoping review is evaluating the available evidence regarding the efficacy of saliva as a diagnostic specimen in COVID-19 patients. […] A systematic literature review of six databases (PubMed, Scopus, The Cochrane Central Register of Controlled Trials [CENTRAL], Science Direct, Web of Science and Google scholar) was carried out without any restrictions on date of publication to identify the reliability of saliva as a diagnostic specimen for detection of SARS-CoV-2 in suspected patients. | 2020-07-24 |
| 32699026 | Diagnosis methods that can broadly differentiate between bacterial and viral sepsis at the initial stage after the development of sepsis are limited. […] This review aims to give a brief summary of current knowledge of the epidemiology, pathophysiology, diagnosis and treatment of viral sepsis. | 2020-07-24 |
| 32699117 | During this crisis, it became clearer than ever what an asset digital diagnostics is to keep pathologists, residents, molecular biologists and pathology assistants engaged in the diagnostic process, allowing social distancing and a ‘need to be there’ on-the-premises policy, while working effectively from home. | 2020-07-24 |
| 32699149 | Around the tenth day after diagnosis, ∼20% of patients with coronavirus disease 2019 (COVID-19)-associated pneumonia evolve toward severe oxygen dependence (stage 2b) and acute respiratory distress syndrome (stage 3) associated with systemic inflammation often termed a “cytokine storm.” | 2020-07-24 |
| 32699167 | The primary outcome is the time to diagnosis of COVID-19. | 2020-07-24 |
| 32699182 | The diagnosis between COVID-19-induced pneumonia and immunotherapy-induced pneumonitis may be challenging in the era of COVID-19 outbreak. | 2020-07-24 |
| 32699509 | For instance, brain imaging techniques show concrete morphological alterations in early childhood and during adolescence that are associated with intensive digital media use. | 2020-07-24 |
| 32699547 | To prevent damage to the coronary arteries, treatment should be started as soon as the diagnosis is made. […] Early diagnosis and prompt treatment are important to achieve optimal treatment outcome in KD. […] Family history of KD among siblings enables clinicians for an earlier diagnosis so as to prevent the disease complications particularly in patients with incomplete features. | 2020-07-24 |
| 32699677 | This report discusses the case of a pediatric patient with perforated appendicitis with a secondary diagnosis of coronavirus disease 2019 (COVID-19). | 2020-07-24 |
| 32700005 | Quick implementation of specific protocols and protective measures in a tertiary hospital in Spain allowed for the early diagnosis and optimal management of patients with SARS-CoV-2 infection and proper protection of staff and inpatients. | 2020-07-24 |
| 32700269 | This paper discusses about the role of machine learning techniques for getting important insights like whether lung computed tomography (CT) scan should be the first screening/alternative test for real-time reverse transcriptase-polymerase chain reaction (RT-PCR), is COVID-19 pneumonia different from other viral pneumonia and if yes how to distinguish it using lung CT scan images from the carefully selected data of lung CT scan COVID-19-infected patients from the hospitals of Italy, China, Moscow and India? […] For training and testing the proposed system, custom vision software of Microsoft azure based on machine learning techniques is used. | 2020-07-24 |
| 32700510 | In this review we will present recent information about the SARS-CoV-2 focusing on the origin, clinical picture, diagnostic methods, structure, replication cycle of SARS-CoV-2 and potential pharmaceutical measures against COVID-19. | 2020-07-24 |
| 32700561 | Here we focus on the role of serum ferritin for diagnostic and clinical management of patients with COVID-19 in comparison with other infectious and non-infectious diseases.METHODS: We examined scientific articles listed in PubMed reporting on ferritin in various infectious and non-infectious diseases. […] All COVID-19 studies published between February and May 2020, which documented laboratory serum ferritin, indicate ferritin as a diagnostic biomarker of COVID-19 severity in hospitalized patients.CONCLUSIONS: Serum ferritin may be considered both a prognostic and stratifying biomarker that can also contribute to therapeutic decision-making concerning patients with COVID-19. | 2020-07-24 |
| 32700670 | Antibody levels declined over 3 months following diagnosis, emphasising the importance of the timing of convalescent plasma collections. | 2020-07-24 |
| 32700671 | In particular, mAb 1A9 was demonstrated to detect S protein in SARS-CoV-2-infected cells and is suitable for use in a sandwich ELISA format.ConclusionThe cross-reactive mAbs may serve as useful tools for SARS-CoV-2 research and for the development of diagnostic assays for COVID-19. | 2020-07-24 |
| 32701240 | Ninety-three patients with confirmed diagnosis of COVID-19 admitted in Ezhou Central Hospital from February to April in 2020 were analyzed. […] Among them, 43 patients were selected from Intensive Care Unit (ICU) with the diagnosis of critical type of COVID-19, and 50 cases of common type were selected from the Department of Respiratory Medicine. | 2020-07-24 |
| 32701376 | The aim was to compare the laboratory data of patients with suspected and confirmed new coronavirus pneumonia (COVID-19) and look for diagnostic predictive and early warning indicators, which will help to better manage the disease. […] Fibrinogen is a valuable diagnostic predictor for patients with suspected COVID-19. | 2020-07-24 |
| 32701726 | Within the seven studies displaying positive results, the majority of positive patients (86.8%) was from not yet peer-reviewed studies including weak data and heterogeneous techniques for sample testing. | 2020-07-24 |
| 32701941 | Using serologic tests to detect the presence of SARS-CoV-2 antibodies is an adjunctive strategy that estimates the prevalence of past infection in a population. | 2020-07-24 |
| 32702087 | The primary outcome is the proportion of patients with a diagnosis of myocardial inflammation. | 2020-07-24 |
| 32702176 | Endoscopy is widely used as a clinical diagnosis and treatment method for certain hepatobiliary and pancreatic diseases. | 2020-07-24 |
| 32702310 | Since a national lockdown was introduced across the UK in March, 2020, in response to the COVID-19 pandemic, cancer screening has been suspended, routine diagnostic work deferred, and only urgent symptomatic cases prioritised for diagnostic intervention. […] In this study, we estimated the impact of delays in diagnosis on cancer survival outcomes in four major tumour types. […] We use a routes-to-diagnosis framework to estimate the impact of diagnostic delays over a 12-month period from the commencement of physical distancing measures, on March 16, 2020, up to 1, 3, and 5 years after diagnosis. […] To model the subsequent impact of diagnostic delays on survival, we reallocated patients who were on screening and routine referral pathways to urgent and emergency pathways that are associated with more advanced stage of disease at diagnosis. […] We considered three reallocation scenarios representing the best to worst case scenarios and reflect actual changes in the diagnostic pathway being seen in the NHS, as of March 16, 2020, and estimated the impact on net survival at 1, 3, and 5 years after diagnosis to calculate the additional deaths that can be attributed to cancer, and the total years of life lost (YLLs) compared with pre-pandemic data. […] Across the three different scenarios, compared with pre-pandemic figures, we estimate a 7·9-9·6% increase in the number of deaths due to breast cancer up to year 5 after diagnosis, corresponding to between 281 (95% CI 266-295) and 344 (329-358) additional deaths. […] For colorectal cancer, we estimate 1445 (1392-1591) to 1563 (1534-1592) additional deaths, a 15·3-16·6% increase; for lung cancer, 1235 (1220-1254) to 1372 (1343-1401) additional deaths, a 4·8-5·3% increase; and for oesophageal cancer, 330 (324-335) to 342 (336-348) additional deaths, 5·8-6·0% increase up to 5 years after diagnosis. […] Substantial increases in the number of avoidable cancer deaths in England are to be expected as a result of diagnostic delays due to the COVID-19 pandemic in the UK. […] Urgent policy interventions are necessary, particularly the need to manage the backlog within routine diagnostic services to mitigate the expected impact of the COVID-19 pandemic on patients with cancer. | 2020-07-24 |
| 32702311 | From these numbers, we estimated the aggregate number of lives and life-years lost in England for per-patient delays of 1-6 months in presentation, diagnosis, or cancer treatment, or a combination of these. […] Using referral-to-diagnosis conversion rates and COVID-19 case-fatality rates, we also estimated the survival increment per patient referred. […] Compared with all diagnostics for the backlog being done in month 1 after lockdown, additional capacity across months 1-3 would result in 90 additional lives and 1662 live-years lost due to diagnostic delays for the 25% backlog scenario, 183 additional lives and 3362 life-years lost under the 50% backlog scenario, and 276 additional lives and 5075 life-years lost under the 75% backlog scenario. […] However, a delay in additional diagnostic capacity with provision spread across months 3-8 after lockdown would result in 401 additional lives and 7332 life-years lost due to diagnostic delays under the 25% backlog scenario, 811 additional lives and 14 873 life-years lost under the 50% backlog scenario, and 1231 additional lives and 22 635 life-years lost under the 75% backlog scenario. […] Prompt provision of additional capacity to address the backlog of diagnostics will minimise deaths as a result of diagnostic delays that could add to those predicted due to expected presentational delays. | 2020-07-24 |
| 32702490 | The surgical intervention data evaluated included diagnostic category, case priority, complications, length of hospital stay, and 30-day mortality. | 2020-07-24 |
| 32702547 | Current wastewater treatment techniques are unable to offer complete elimination of antibacterial biocides. | 2020-07-24 |
| 32702851 | Polymerase chain reaction testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the diagnostic gold standard of COVID-19. […] We have developed a simulation-based training program for mobile prehospital diagnostic teams in the province of Styria, Austria, and performed a prospective observational study on its applicability and effectivity.The 1-day curriculum uses theoretical instruction, technical skills training, and simulator-based algorithm training to teach and train prehospital patient identification and communication, donning the personal protective equipment, collection of naso-/oropharyngeal swabs for SARS-CoV-2 polymerase chain reaction testing, doffing the personal protective equipment, and sample logistics. […] Using several proven educational concepts, we have successfully drafted and implemented a training program for mobile prehospital SARS-CoV-2 diagnostic teams. | 2020-07-25 |
| 32702935 | Strengthening infants’ virus screening in families with infected kins is important for early diagnosis, isolation, and treatment when symptoms are atypical. | 2020-07-25 |
| 32702940 | Both at the stage of diagnostics prior to admission to the intensive care unit and during the monitoring of lesion evolution, diagnostic imaging techniques may significantly influence clinical decisions. | 2020-07-25 |
| 32703010 | However, nasopharyngeal swab and blood test confirmed the diagnosis of COVID-19. | 2020-07-25 |
| 32703036 | We have reviewed the literature focusing on the prevention, diagnosis, and treatment of COVID-19. […] The most relevant reports from the recent two decades were collected utilizing keywords including SARS-CoV, MERS-CoV, COVID-19, epidemiology, therapeutics and diagnosis. […] Based on this literature review, both traditional and emerging approaches are vital for the prevention, diagnosis and treatment of COVID-19. […] The traditional sciences play an essential role in the preventive and supportive care of corona infection, and modern technologies appear to be useful in the development of precise diagnosis and powerful treatment approaches for this disease. | 2020-07-25 |
| 32703158 | Here I use simulations to explore how experiment sample size and degrees of sample pooling impact precision of prevalence estimates and potential for minimizing the total number of tests required to get individual-level diagnostic results. | 2020-07-25 |
| 32703188 | The dogs were able to discriminate between samples of infected (positive) and non-infected (negative) individuals with average diagnostic sensitivity of 82.63% (95% confidence interval [CI]: 82.02-83.24%) and specificity of 96.35% (95% CI: 96.31-96.39%). | 2020-07-25 |
| 32703209 | The aim of this was to analyze 4 chest CT imaging features of patients with coronavirus disease 2019 (COVID-19) in Shenzhen, China so as to improve the diagnosis of COVID-19. […] In clinical work, accurate identification of various chest CT signs can help to improve the diagnostic accuracy of COVID-19 and reduce the misdiagnosis or missed diagnosis rate. | 2020-07-25 |
| 32703636 | We reviewed all relevant articles pertaining to kidney, upper tract urothelial cell, bladder, prostate, penile, and testicular cancer in regard to diagnostic, surgical, or treatment delay. | 2020-07-25 |
| 32703647 | To assess the immediate impact of the COVID-19 pandemic on Diagnostic and Interventional Radiology education, and to propose measures to preserve and augment trainee education during future crises. […] Diagnostic Radiology (DR) studies and Interventional Radiology (IR) procedures at a single tertiary-care teaching institution between 2015 and 2020 were reviewed. | 2020-07-25 |
| 32703816 | In addition, it bypasses the need for swab sampling, decreases the risk of the health care personnel involved in the testing process, and accelerates the diagnostic procedure. | 2020-07-25 |
| 32703893 | In this commentary, I describe my experience with CoV disease 2019 (COVID-19), with a focus on being tested at the University of North Carolina-Chapel Hill Respiratory Diagnostic Center on its inaugural day. | 2020-07-25 |
| 32703894 | In this commentary, we provide a broad overview of how the rapidly evolving coronavirus disease 2019 (COVID-19) diagnostic landscape has impacted clinical care during the COVID-19 pandemic. […] We also highlight the progress that has been made in the development and implementation of these assays as well as the need for ongoing improvement in diagnostic testing capabilities. | 2020-07-25 |
| 32703927 | In our institution, we have found the diagnosis of subcutaneous emphysema and pneumomediastinum in COVID-19 patients is associated with unfavorable outcomes and worse prognosis. | 2020-07-25 |
| 32704513 | Its diagnosis primarily depended on real-time polymerase chain reaction (RT-PCR) results. | 2020-07-25 |
| 32705153 | Reverse transcription‑quantitative polymerase chain reaction (RT‑qPCR) is the gold standard method for the diagnosis of COVID‑19 infection. […] In conclusion, ddPCR shows higher sensitivity and specificity compared to RT‑qPCR for the diagnosis of COVID‑19 infection in false‑negative samples with low viral load. […] Therefore, ddPCR is strongly recommended in clinical practice for the diagnosis of COVID‑19 and the follow‑up of positive patients until complete remission. | 2020-07-25 |
| 32705222 | Diagnosis was confirmed at Zhejiang Hospital by reverse transcription‑PCR (RT‑PCR), which was approved by the Chinese government. […] The present study revealed that epidemiological history was critical to the diagnosis of 2019‑nCoV in low epidemic regions outside Hubei province. | 2020-07-25 |
| 32705298 | The gold standard for detection of an active SARS-CoV‑2 infection is the direct detection of the pathogen with nucleic acid amplification techniques. […] Thanks to modern techniques thousands of SARS-CoV‑2 sequences are already available, which show a genomic variability. | 2020-07-25 |
| 32705368 | This short editorial is reviewing current understanding of this new complication, its pathophysiology, diagnosis and therapeutic strategy. | 2020-07-25 |
| 32705575 | We tested SARS-CoV-2 RNA with commercial kits, investigated the level of serologic IgM and IgG antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using magnetic particle chemiluminescence immunoassays, and compared the results of serologic tests and nucleic acid test (NAT). […] These results supported the combination of serologic testing and NAT in routine COVID-19 diagnosis and provided evidence on the temporal profile of antibody response in patients with different disease severity. | 2020-07-25 |
| 32705809 | These statements were refined into 40 final clinical guidance statements, accompanied by a flow diagram depicting the diagnostic pathway for MIS-C. | 2020-07-25 |
| 32705889 | Patients included had a confirmed laboratory diagnosis of COVID-19 via reverse transcription polymerase chain reaction nasopharyngeal swab for SARS-Cov-2 or radiological evidence of COVID-19. | 2020-07-25 |
| 32705906 | Due to the overgrowing prevalence of MAFLD, it could be speculated that a large proportion of the population might be at risk of severe COVID-19 and the identification of these patients possibly by using liver enzymes as risk predictors may be crucial for an early diagnosis and for the management of the infection. | 2020-07-25 |
| 32706108 | Depending on the severity of hypoxemia different techniques can be used to improve oxygenation. […] The main target audience of this study is not so much pneumonologists or intensivists who have extensive experience in the application of the techniques discussed here, but rather doctors of other specializations who must master new skills in order to help patients during the time of a pandemic. | 2020-07-25 |
| 32706210 | Particularly, echocardiography remains an essential diagnostic service which, due to the close contact with patients during the exam, provides echocardiographers high-risk of contagion. | 2020-07-25 |
| 32706393 | But, it should be done using the most appropriate specimen and an accurate diagnostic test such as real-time reverse transcription-polymerase chain reaction (qRT-PCR). | 2020-07-25 |
| 32706411 | The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) has led to the elaboration of multiple studies to increase knowledge and understanding, hence, having the ability to accomplish an adequate and timely diagnosis and give an optimal treatment according to the patient’s condition. | 2020-07-25 |
| 32706417 | The diagnosis of coronavirus 19 (COVID-19) relies mainly upon viral nucleic acid detection, but false negatives can lead to missed diagnosis and misdiagnosis; severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibody detection is convenient, safe and highly sensitive. | 2020-07-25 |
| 32706615 | Those with a confirmed diagnosis of acute ischemic stroke or transient ischemia attack were included. | 2020-07-25 |
| 32706769 | In the end, he was diagnosed with viral pleuritis as the diagnosis of exclusion. | 2020-07-25 |
| 32706819 | Patients were classified into common and severe groups according to the diagnostic criteria of severe pneumonia. | 2020-07-25 |
| 32706953 | The primary outcome was clinical status at 15 days as assessed with the use of a seven-level ordinal scale (with levels ranging from one to seven and higher scores indicating a worse condition) in the modified intention-to-treat population (patients with a confirmed diagnosis of Covid-19). | 2020-07-25 |
| 32707480 | In addition to mechanical ventilation some other techniques of respiratory support could be used in some forms of COVID-19 related ARF. […] This position paper of the Respiratory Support and Chronic Care Group of the French Society of Respiratory Diseases is intended to help respiratory clinicians involved in care of COVID-19 pandemic in the rational use of non-invasive techniques such as oxygen therapy, CPAP, non-invasive ventilation and high flow oxygen therapy in managing patients outside intensive care unit (ICU). […] The aims are: (1) to focus both on the place of each technique and in describing practical tips (types of devices and circuit assemblies) aimed to limit the risk of caregivers when using those techniques at high risk spreading of viral particles; (2) to propose a step-by-step strategy to manage ARF outside ICU. | 2020-07-25 |
| 32707770 | In the cancer patients group, 89/138 (64.5%) patients had a time interval >5 years between the diagnosis of the tumor and hospitalization. […] In the Reggio Emilia Study, the incidence of hospitalization for COVID-19 in people with previous diagnosis of cancer is similar to that in the general population (standardized incidence ratio 98; 95% CI 73-131), and it does not appear to have a more severe course or a higher mortality rate than patients without cancer. | 2020-07-26 |
| 32707965 | To date, 38 cases have been reported, with other cases most likely undiagnosed mainly due to a lack of clinical awareness and diagnostic screening. […] Herein is a review of 38 published CAPA cases, which highlights the diagnostic and therapeutic challenges posed by this novel fungal co-infection. | 2020-07-26 |
| 32707972 | The rampant spread of COVID-19 and the worldwide prevalence of infected cases demand a rapid, simple, and cost-effective Point of Care Test (PoCT) for the accurate diagnosis of this pandemic. […] The most common molecular tests approved by regulatory bodies across the world for COVID-19 diagnosis are based on Polymerase Chain Reaction (PCR). […] These limitations have inspired researchers to search for alternative diagnostic methods that are fast, economical, and executable in low-resource laboratory settings. […] The discovery of Loop-mediated isothermal Amplification (LAMP) has provided a reliable substitute platform for the accurate detection of low copy number nucleic acids in the diagnosis of several viral diseases, including epidemics like Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS). […] At present, a cocktail of LAMP assay reagents along with reverse transcriptase enzyme (Reverse Transcription LAMP, RT-LAMP) can be a robust solution for the rapid and cost-effective diagnosis for COVID-19, particularly in developing, and low-income countries. […] In summary, the development of RT-LAMP based diagnostic tools in a paper/strip format or the integration of this method into a microfluidic platform such as a Lab-on-a-chip may revolutionize the concept of PoCT for COVID-19 diagnosis. […] This review discusses the principle, technology and past research underpinning the success for using this method for diagnosing MERS and SARS, in addition to ongoing research, and the prominent prospect of RT-LAMP in the context of COVID-19 diagnosis. | 2020-07-26 |
| 32708264 | Here, we describe clinical and biological features, including the screening of CHIP mutants in a well-annotated cohort of 122 hospitalized patients with a laboratory-confirmed diagnosis of COVID-19 (55% requiring OTI). | 2020-07-26 |
| 32708526 | We conclude that Se status analysis in COVID patients provides diagnostic information. | 2020-07-26 |
| 32708750 | Diagnosis may be retrospective, based on seroconversion, as PCR may be negative. | 2020-07-26 |
| 32708803 | Furthermore, average increases of 4% to 11% in COVID-19 detection accuracy are reported in favour of the proposed data-augmented deep learning models relative to the machine learning techniques. […] Therefore, the proposed algorithm is effective in performing a rapid and consistent Corona virus diagnosis that is primarily aimed at assisting clinicians in making accurate identification of the virus. | 2020-07-26 |
| 32708840 | In lines with previous data, our results suggest that the E-gene stands as the most conserved and reliable target when considering single-gene target testing for molecular diagnosis of SARS-CoV-2 in South America. | 2020-07-26 |
| 32708870 | Quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) is currently used for the clinical diagnosis of SARS-CoV-2 infection using nasopharyngeal swabs, tracheal aspirates, or bronchoalveolar lavage (BAL) samples. | 2020-07-26 |
| 32709055 | Conservation of these antigens among viral strains is critical to ensure optimum diagnostic test performance and broad protective efficacy, respectively. […] In conclusion, the N and S antigens of SARS-CoV-2 are well-conserved antigens, but new clades are emerging and may need to be included in future diagnostic and vaccine formulations. | 2020-07-26 |
| 32709413 | Telephone interviews were used to administer a clinical questionnaire to patients, and e-mail was used to receive the results of diagnostic tests conducted in outpatient settings. | 2020-07-26 |
| 32709482 | Patients who died were older than survivors, had a longer time from transplant and a worse clinical presentation at diagnosis. | 2020-07-26 |
| 32709495 | Age and cancer diagnosis are significant predictors of adverse outcomes of the COVID-19 infection. | 2020-07-26 |
| 32709505 | Multivariable logistic regression analysis demonstrated poor general condition, shorter duration after BC diagnosis, aggressive BC molecular subtypes, and close contact with patients with COVID-19 as independent factors associated with anxiety. | 2020-07-26 |
| 32709542 | In this commentary, we review the new diagnosis of prolonged grief disorder and outline why we might anticipate increased rates of this condition on the heels of COVID-19, especially among older persons. | 2020-07-26 |
| 32709566 | We aimed to identify effective techniques for surgeons to build relationships during a video consult, and to design and pilot a class that increased student skill in communicating during a video consult. | 2020-07-26 |
| 32709733 | Respondents reported an average decline of 54% in diagnostic procedures. […] Conclusion: Both diagnostic and therapeutic nuclear medicine procedures declined precipitously, with countries worldwide being affected by the pandemic to a similar degree. | 2020-07-26 |
| 32709770 | Records of all the patients who presented from March 25th to May 3rd, 2020 were scanned to evaluate the details regarding the presenting complaints, diagnosis, advised treatment and surgical interventions. | 2020-07-26 |
| 32710056 | Issues were identified with clinical diagnosis from sectional panoramic radiographs, which led to the introduction of extraoral bitewings being taken as an alternative. […] A quality assurance audit found that these images provided a substantially lower radiation dose and produced excellent quality images with improved diagnostic accuracy. | 2020-07-26 |
| 32710269 | A better understanding of B- and T-cell immunity is critical to the diagnosis, treatment and prevention of coronavirus disease 2019 (COVID-19). | 2020-07-26 |
| 32710297 | Such programs include diagnostic procedures (spirometry, ECG, blood tests) and treatments like respiratory physio-kinesiotherapy and postural drainage of the lungs; mechanical pulmonary ventilation for rehabilitative purposes, with or without drugs, along with standard medical and, when required, oxygen therapy; inhalation therapies with mineral waters; physical activity and psychological support. | 2020-07-26 |
| 32710500 | Active chemotherapy, viral load at diagnosis and COVID-19 therapy were not predictors of outcome. | 2020-07-26 |
| 32710571 | We review several current and potential genetic (DNA) and transcriptional (RNA)-based parameters in women with infertility that can be significant in diagnosis and treatment. | 2020-07-26 |
| 32710639 | Infected individuals with suspected (clinical diagnosis) or laboratory-confirmed COVID-19 infection were recruited. […] Interestingly, our statistical analysis did not show any significant difference, either for general symptoms or otorhinolaryngological features, between the clinical diagnosis group and the laboratory-confirmed diagnosis (polymerase chain reaction) group. | 2020-07-26 |
| 32710646 | Patients were admitted with confirmed diagnosis of COVID-19 between 1 March and 15 April 2020. | 2020-07-26 |
| 32710647 | In the COVID-19 group, nine patients were enrolled after diagnosis. | 2020-07-26 |
| 32710733 | The stimulation could occur by way of IL-6 / JAK2 / STAT3 / SOCS3 and NF-κB (p65)/IL-18, which work together to induce AKI and increase overall renal-related diagnostic markers, such as plasma creatinine and tubular cell damage. | 2020-07-26 |
| 32710927 | Routine history, physical examination, laboratory testing, electrocardiography, and plain x-ray imaging may often suffice for such patients, but given overlap between COVID-19 and typical cardiovascular diagnoses such as heart failure and acute myocardial infarction, need frequently arises for advanced imaging techniques to assist in differential diagnosis and management. […] For each, the authors consider the role of biomarker testing to guide imaging decision-making, provide differential diagnostic considerations, and offer general suggestions regarding application of various advanced imaging techniques. | 2020-07-26 |
| 32710999 | Therefore, the Italian Diabetes and Pregnancy Study Group, together with a group of experts, developed these recommendations in order to guide physicians in the management of HIP, providing specific diagnostic, therapeutic and assistance pathways (PDTAs) for the COVID-19 emergency. | 2020-07-26 |
| 32711871 | To conduct a systematic review of original peer-reviewed studies, containing data on the identification of SARS-CoV-2 in clinical samples of amniotic fluid, placenta or membranes, umbilical cord blood, and human milk, from women with a clinically or confirmed diagnosis of COVID-19. […] Following our search criteria, we found no studies that demonstrate the detection of SARS-CoV-2, in conjunction with viral isolation and the evaluation of the infective capacity of viral particles, in clinical samples of amniotic fluid, placenta or membranes, umbilical cord blood and human milk, from women with a confirmed or clinical diagnosis of COVID-19. | 2020-07-27 |
| 32711946 | Diagnostic accuracy was highlighted as a concern for both clinicians and patients due to inherent inability to conduct a traditional clinical examination, notable in 43.5% of qualitative comments. | 2020-07-27 |
| 32712031 | Point-of-care ultrasound provides numerous benefits to emergency providers caring for patients with COVID-19, including decreasing resource utilization, assisting in diagnosis, guiding management of the critically ill patient, and aiding in rapid triage of patients under investigations for COVID-19. | 2020-07-27 |
| 32712116 | Secondary endpoints comprised presenting symptoms, diagnosis, prescriptions, adverse effects, and progression of monthly consulting turnover. | 2020-07-27 |
| 32712235 | A previously healthy 45-year-old man was admitted to our emergency department with sudden-onset chest pain and progressive shortness of breath 17 days after diagnosis with uncomplicated COVID-19 infection. | 2020-07-27 |
| 32712309 | The aim of this article is to outline the fundamentals of ARDS diagnosis and management, including mechanical ventilation, for the nonintensivist. | 2020-07-27 |
| 32712426 | Our final diagnosis was an inflammatory encephalopathy related to a SARS-CoV2 infection. | 2020-07-27 |
| 32713374 | Using information from South London and Maudsley NHS Foundation Trust (SLAM) clinical records, via the Clinical Record Interactive Search system, we identified 6309 individuals who had an ICD-10 diagnosis of schizophrenia-spectrum disorders and were taking antipsychotics at the time of the COVID-19 pandemic onset in the UK. | 2020-07-28 |
| 32713385 | Absolute isolation and atraumatic restorative therapy techniques are a good alternative to decrease fluid exposure. | 2020-07-28 |
| 32713389 | As the largest obstetrics and gynecology hospital in North China, here we summarize the diagnosis and treatment process and key points of obstetrics and gynecology patients in our hospital during the period of the COVID-19 pandemic, hoping to provide available information to inform care of obstetrics and gynecology patients. | 2020-07-28 |
| 32713663 | Clinical records of all participants were examined to obtain information regarding age, sex, mechanism of injury, and diagnosis. | 2020-07-28 |
| 32713715 | The consistency of LUS and chest CT in follow-up was 0.596, with higher consistency in diagnosis of lesion progression (Kappa values was 0.774). | 2020-07-28 |
| 32713924 | A 69-year-old man was admitted to our hospital under diagnosis of pneumonia due to severe acute respiratory syndrome-corona virus 2 (SARS-CoV-2) (Day 0). | 2020-07-28 |
| 32715080 | Real-time reverse transcription-PCR (RT-PCR) assays remain the molecular test of choice for the etiologic diagnosis of SARS-CoV-2 infection while radiographic findings (chest computed tomography [CT]) and antibody-based techniques are being introduced as supplemental tools. | 2020-07-28 |
| 32715448 | With constantly evolving materials and techniques used in wound closure management for total knee arthroplasty (TKA), it is imperative that we continuously evaluate new modalities and techniques to optimize healing. | 2020-07-28 |
| 32715672 | Serologic testing for immunoglobulin G antibody based on immunochromatographic assay was conducted in 103 patients and 95 guardians aged 18 to 82 years without any history of COVID-19 diagnosis, who visited outpatient clinics of a single university-affiliated hospital from May 25 to June 5, 2020. | 2020-07-28 |
| 32716073 | Diagnosis of vitamin D deficiency could be a helpful adjunct in assessing patients’ potential of developing severe COVID-19. | 2020-07-28 |
| 32716647 | While there are studies under way to characterize the direct effects of the COVID-19 pandemic on the care of patients with cancer, there have been few quantitative reports of the impact that efforts to control the pandemic have had on the normal course of cancer diagnosis and treatment encounters. | 2020-07-28 |
| 32716648 | There is an urgent requirement for an extensive research of CoV infections to disclose the route of extension, pathogenesis, and diagnosis and then to recognize the therapeutic targets to facilitate disease control and surveillance. | 2020-07-28 |
| 32716758 | Although 48 HCWs were exposed to these six cases, delayed diagnosis was averted and no evidence of spread to patients or HCWs was detected. | 2020-07-28 |
| 32716893 | Therefore, early and accurate diagnosis is essential to control disease progression. […] The aim of this review was to identify the diagnostic value of different imaging modalities used for diagnosis of COVID-19. […] The keywords diagnostic imaging, radiology, respiratory infection, pneumonia, coronavirus infection and COVID-19 were used to identify radiology articles focusing on the diagnosis of COVID-19 and to determine the diagnostic value of various imaging modalities, including x-ray, computed tomography (CT), ultrasound, and nuclear medicine for identification and management of infected patients. […] Studies that investigated the diagnostic roles and imaging features of patients with COVID-19, using either chest CT, lung ultrasound, chest x-ray, or positron emission topography/computed tomography (PET/CT) scan, were discussed. […] Of these imaging modalities, chest x-ray and CT scan are the most commonly used for diagnosis and management of COVID-19 patients, with chest CT scan being more accurate and sensitive in identifying COVID-19 at early stages. […] Chest CT scan remains the most sensitive imaging modality in initial diagnosis and management of suspected and confirmed patients with COVID-19. […] Other diagnostic imaging modalities could add value in evaluating disease progression and monitoring critically ill patients with COVID-19. | 2020-07-28 |
| 32716900 | In the first months of 2020, a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began circulating widely in the American state of Colorado, leading to widespread diagnosis of coronavirus disease (COVID-19), hospitalizations, and deaths. | 2020-07-28 |
| 32717056 | While molecular techniques remain the gold standard for diagnosis of acute SARS-CoV-2 infection, serological tests have the unique potential to ascertain how much of the population has been exposed to the COVID-19 pathogen. | 2020-07-28 |
| 32717210 | Capacity for acute diagnosis via PCR testing was limited for individuals with mild to moderate SARS-CoV-2 infection in the early phase of the COVID-19 pandemic and a substantial proportion of health-care workers with suspected infection were not tested. | 2020-07-28 |
| 32717345 | This presents a new challenge in the diagnosis and control of COVID-19 infection with a caution for proper sanitation and hygiene. | 2020-07-28 |
| 32718076 | A serum sodium concentration threshold of less than 135 mmol/L is diagnostic for hyponatremia. […] Our review aims to summarize the diagnostic value and impact of hyponatremia on the prognosis, length of the hospitalization, and mortality among patients with active infection. […] Hyponatremia can also play a diagnostic role in differentiating pathogens that cause a certain infection type, as it was observed in community-acquired pneumonia. | 2020-07-29 |
| 32718292 | Awareness of such an association could create new insight to consider neurological manifestations as a COVID-19 differential diagnosis during the pandemic period of COVID-19, to avoid delayed diagnosis and prevent further transmission. | 2020-07-29 |
| 32718855 | We conducted a cross-sectional study starting on March 29 to April 5, 2020 based on a national online survey using snowball sampling techniques. | 2020-07-29 |
| 32718894 | Timely medical treatment and clear diagnosis after the onset might be beneficial to control the condition of COVID-19. | 2020-07-29 |
| 32718896 | There is a diverse range of SARS-CoV-2 detection rates in reported studies, with uncertainty as to the optimal sampling strategy for COVID-19 diagnosis and monitoring. […] The results support sputum sampling as a valuable method of COVID-19 diagnosis and monitoring, and highlight the importance of early testing after symptom onset to increase the rates of COVID-19 diagnosis. | 2020-07-29 |
| 32718949 | Using our rapid and ongoing deployment as a case study of social science techniques applied to a pandemic, we describe how other health systems might leverage social science to improve their preparations and communications. | 2020-07-29 |
| 32719001 | In addition, we developed a multiplexed sequencing protocol (LAMP-sequencing) as a diagnostic validation procedure to detect and record the outcome of RT-LAMP reactions. | 2020-07-29 |
| 32719203 | The relevance, mode of operation and value addition of this essential public health service are discussed in the context of inter departmental collaboration and interaction with other institutes through the existing diagnostic, surveillance and infection control networks. | 2020-07-29 |
| 32719204 | Timely diagnosis is essential for the containment of the disease and breaks in the chain of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). […] The present situation demands the countries to scale up their testing and design innovative strategies to conserve diagnostic kits and reagents. […] The pooling of samples saves time, workforce and most importantly diagnostic kits and reagents. | 2020-07-29 |
| 32719214 | This study aims to provide scientific basis for rapid screening and early diagnosis of the coronavirus disease 2019 (COVID-19) through analysing the clinical characteristics and early imaging/laboratory findings of the inpatients. […] Personalised criteria should be formulated according to different age groups in the early screening and diagnosis stage. | 2020-07-29 |
| 32719688 | We report a case of an 8-year-old girl who underwent a SARS-CoV-2 infection manifesting with atypical symptoms spearheaded by abdominal discomfort and systemic inflammation and partially mimicking hemophagocytic lymphohistiocytosis (HLH) or macrophage activation syndrome (MAS), which however did not fulfill the HLH/MAS diagnostic criteria. | 2020-07-29 |
| 32719767 | Integration of artificial intelligence (AI) techniques in wireless infrastructure, real-time collection, and processing of end-user devices is now in high demand. […] However, the current rapid and exponential rise in the number of patients has necessitated efficient and quick prediction of the possible outcome of an infected patient for appropriate treatment using AI techniques. | 2020-07-29 |
| 32720012 | Two scenarios were identified: (a) patients who were admitted to a hospital for an acute surgical condition with a concomitant diagnosis of COVID-19, and (b) patients with severe COVID-19 developing acute abdominal pathologies during their hospital stay. | 2020-07-29 |
| 32720082 | A careful understanding of the hemodynamic and diagnostic implications is essential for appropriate triage and management of these patients. | 2020-07-29 |
| 32720214 | Dynamic characteristics of SARS-CoV-2-specific antibodies which are important for diagnosis of infection have not been fully demonstrated. […] In conclusion, antibodies should be detected to aid in diagnosis of COVID-19 infection. […] IgG could be a sensitive indicator for retrospective diagnosis and contact tracing, while IgM could be an indicator of early infection. | 2020-07-29 |
| 32720233 | It is currently unknown whether concomitant SARS-CoV-2 infection and GBS are pathophysiologically related, what biomarkers are useful for diagnosis, and what is the optimal treatment given the medical comorbidities, complications, and simultaneous infection. […] We report a patient who developed severe GBS following SARS-CoV-2 infection at the peak of the initial COVID-19 surge (April 2020) in New York City and discuss diagnostic and management issues and complications that may warrant special consideration in similar patients. | 2020-07-29 |
| 32720259 | Age, sex, comorbidities, rheumatic disease diagnosis and treatment, disease activity prior to infection, radiographic and laboratorial results at arrival were analysed. | 2020-07-29 |
| 32720703 | This disease is associated with a wide range of symptoms, which makes accurate diagnosis of it difficult. | 2020-07-29 |
| 32720704 | To overcome COVID-19, appropriate diagnosis methods are urgently needed. | 2020-07-29 |
| 32720706 | Results reinforce the importance of including coronaviruses in diagnostic panels used by official surveillance systems because besides their pandemic potential, endemic HCoVs are associated to severe disease in healthy adults. | 2020-07-29 |
| 32720827 | The serotonin release assay eventually returned positive, which confirmed the diagnosis of HIT. | 2020-07-29 |
| 32721387 | Differential diagnosis of COVID-19 includes a broad range of conditions. […] Our aim was to develop a tool to identify patients with higher probability of COVID-19 diagnosis at admission. […] Predictive models of COVID-19 diagnosis were performed based on radiology, clinical and laboratory findings; bootstrapping was performed in order to account for overfitting. […] Variables associated with COVID-19 diagnosis in multivariate analysis were leukocyte count ≤7.7×103mm-3, LDH >273U/L, and chest radiographic abnormality. […] A predictive score was built for COVID-19 diagnosis, with an area under ROC curve of 0.847 (95% CI 0.77-0.92), 96% sensitivity and 73.5% specificity. | 2020-07-30 |
| 32721605 | We focus on infant food allergy prevention, management of anaphylaxis, accurate diagnosis with oral food challenges, and active management of food allergy with oral immunotherapy. | 2020-07-30 |
| 32721813 | Utilising biomarkers for COVID-19 diagnosis, prediction of treatment response and overall prognostication have been investigated recently. | 2020-07-30 |
| 32722014 | The economic and health crisis created by the COVID-19 pandemic as well as the public health measures currently taken to stop the spread of the virus may have an impact on household TB transmission, treatment and diagnostic services, and TB prevention and control programs. | 2020-07-30 |
| 32722174 | To date, numerous measures have been applied by the government and the medical community during the early stages of the COVID-19 outbreak including the reporting of methods for diagnostic testing, patient classification, the introduction of drive-through screening centers, COVID-19 preventive measures, implementation of government policies for the shortage of face masks, and entry restrictions. | 2020-07-30 |
| 32722191 | Comparative data of SARS-CoV-2 IgM/IgG serology rapid diagnostic tests (RDTs) is scarce. […] The diagnostic accuracy of three commercially available COVID-19 RDTs: NTBIO (RDT-A), Orient-Gene (RDT-B), and MEDsan (RDT-C), against both a recombinant spike-expressing immunofluorescence assay (rIFA) and Euroimmun IgG ELISA, was assessed. […] These RDTs could be considered in the absence of routine diagnostic serology facilities. | 2020-07-30 |
| 32722711 | Participants with self-reported history of a mental health diagnosis had significantly higher distress, health anxiety, and COVID-19 fears than those without a prior mental health diagnosis. | 2020-07-30 |
| 32723142 | This review discusses the potential therapeutic approaches, in addition to the contribution of nanomedicine against CoVs in the fields of vaccination, diagnosis and therapy. | 2020-07-30 |
| 32723430 | Many serologic tests are now available for measuring severe acute respiratory syndrome coronavirus 2 antibodies to evaluate potential protective immunity and for seroprevalence studies. | 2020-07-30 |
| 32723432 | Our EQA panel identified the potential weaknesses of currently available commercial reagent kits. | 2020-07-30 |
| 32723441 | The second tier assessed intervention measures according to six building blocks of WHO: strategic vision highlighted by National Action Plan COVID-19, inadequacy and urban bias of healthcare professionals, expanded bed capacity, enhanced laboratory diagnostic capacity and financial assistance. | 2020-07-30 |
| 32723446 | Considering the current pandemic, provisional diagnosis of meningoencephilits, with bilateral pneumonia owing to COVID-19, was made. | 2020-07-30 |
| 32723448 | During COVID-19 pandemic, chest computed tomography (CT) imaging has become an important tool with high sensitivity for diagnosis due to the low positive rate of the real-time reverse-transcriptase polymerase chain reaction (RT-PCR). […] Furthermore, the chest CT has played an important role in the diagnosis of underlying pulmonary lesions. | 2020-07-30 |
| 32723450 | Computerised Tomographic (CT) scan may play an important role in the diagnosis and management of the COVID -19-the disease caused by the SARS-Cov-2. […] This is especially important as the definitive diagnosis via RT-PCR (Reverse Transcriptase - Polymerase Chain Reaction) would take almost 24 hours in the present time in India. | 2020-07-30 |
| 32723452 | CT can be used as the first choice for early diagnosis of COVID-19 pneumonia. | 2020-07-30 |
| 32723697 | For each stage in the COVID-19 outcome continua (population, infection experience, diagnosis, hospitalization, fatality), we synthesized the most recent publicly available data. | 2020-07-30 |
| 32723996 | Thus the use of CT thoraxfor early diagnosis may be reserved for patients in the older agegroups, and not in younger patients. | 2020-07-30 |
| 32724238 | In order to distinguish suitable subjects from those not suitable for home isolation, the reference criterion cannot be the only diagnostic element, but it will be necessary to take into account above all the severity of the condition. | 2020-07-30 |
| 32724793 | Although the cutaneous presentations of COVID-19 are infrequent, it is of great importance for all clinicians to be aware of these manifestations, as it may contribute to sooner and better diagnosis and management of the disease, even in asymptomatic or paucisymptomatic patients. | 2020-07-30 |
| 32725080 | Diagnosis is central and is the first step in recognizing and fighting any infectious agent. | 2020-07-30 |
| 32725148 | The CBCs of these patients, following a confirmed diagnosis of COVID-19, were retrospectively analyzed and a significant P<0.05 was found after a full statistical analysis was conducted using the Statistical Package for the Social Sciences (IBM SPSS). | 2020-07-30 |
| 32725501 | Favorable responses to remote diagnostic capabilities suggest that these offerings improve preference for teledermatology. | 2020-07-30 |
| 32725536 | Diagnosis is usually via real-time PCR, and it is unclear whether the semi-quantitative capability of this method, determining viral load through cycle threshold (Ct) values, can be leveraged. | 2020-07-30 |
| 32725833 | Ultrasound plays an indispensable role in the diagnosis, monitoring, and follow-up of patients with COVID-19. […] In this study, we used a robotic tele-echography system based on a 5G communication network for remote diagnosis. | 2020-07-30 |
| 32725884 | Understanding the epidemiological characteristics, clinical characteristics, and diagnosis and treatment of the first patients in various countries are of great significance for the identification, prevention and control of COVID-19. | 2020-07-30 |
| 32725955 | Early detection of children with mild symptoms or an asymptomatic state and early diagnosis of MIS-C are mandatory for the management of COVID-19 and the prevention of transmission and a severe inflammatory state. | 2020-07-30 |
| 32726004 | The analyzed results of the TCM patents from the patent information sharing platform of COVID-19 were consistent with the Guideline of Diagnosis and Treatment of COVID-19(7th edition), and the combination of TCM in each cluster may also provide future directions for drug compatibility. | 2020-07-30 |
| 32726006 | In this study, 45 prescriptions of Mongolian medicine for the prevention of COVID-19 were collec-ted and further analyzed, hoping to provide new ideas for clinical diagnosis and treatment. | 2020-07-30 |
| 32726007 | The model can simulate the traditional Chinese medicine treatment of common disease syndromes in Coronavirus Disease 2019 Diagnosis and Treatment Program(the sixth edition for trial). | 2020-07-30 |
| 32726008 | This study analyzed the application of classic prescriptions in the diagnosis and treatment schemes based on the Diagnosis and Treatment Schemes for Coronavirus Disease at the country, provincial and municipal levels, and further explored its disrobing effect on COVID-19 disease severe phase network, and selected representative prescriptions for core target screening and gene enrichment analysis, so as to reveal its mechanism of action. | 2020-07-30 |
| 32726155 | Bedside skills have been declining over the last two decades, with multiple studies reporting increasing reliance on investigations and technology in making diagnostic decisions. […] Overreliance on investigations could drive up costs of healthcare if every diagnosis depends on a head to toe scan. | 2020-07-30 |
| 32726172 | The aim of this study was to evaluate the sensitivity, specificity and capacity of a fully automated, random access high-throughput real-time PCR-based diagnostic platform for the detection of SARS-CoV-2. | 2020-07-30 |
| 32726234 | The response to COVID-19 in the United States has been hampered by an overall lack of diagnostic testing capacity. | 2020-07-30 |
| 32726240 | Current recommendations for diagnostic imaging for moderately to severely ill patients with suspected coronavirus disease 2019 (COVID-19) include chest radiograph (CXR). […] Our primary objective was to determine whether lung ultrasound (LUS) B-lines, when excluding patients with alternative etiologies for B-lines, are more sensitive for the associated diagnosis of COVID-19 than CXR. […] This was a retrospective cohort study of all patients who presented to a single, academic emergency department in the United States between March 20 and April 6, 2020, and received LUS, CXR, and viral testing for COVID-19 as part of their diagnostic evaluation. […] The primary objective was to estimate the test characteristics of both LUS B-lines and CXR for the associated diagnosis of COVID-19. […] LUS was more sensitive (88.9%, 95% confidence interval (CI), 71.1-97.0) for the associated diagnosis of COVID-19 than CXR (51.9%, 95% CI, 34.0-69.3; p = 0.013). […] This data could have important implications as an aid in the diagnostic evaluation of COVID-19, particularly where viral testing is not available or restricted. | 2020-07-30 |
| 32726291 | Nevertheless, as cancer control depends also on other health services and additionally major changes in people’s behaviour likely occurred, we aimed to analyse whether cancer diagnosis and management were affected during the COVID-19 epidemic in Slovenia. […] Methods We analysed routine data for the period November 2019 through May 2020 from three sources: (1) from the Slovenian Cancer Registry we analysed data on pathohistological and clinical practice cancer notifications from two major cancer centres in Ljubljana and Maribor; (2) from the e-referral system we analysed data on all referrals in Slovenia issued for oncological services, stratified by type of referral; and (3) from the administrative data of the Institute of Oncology Ljubljana we analysed data on outpatient visits by type as well as on diagnostic imaging performed. […] Conclusions Significant drops in first referrals for oncological services, first visits and imaging studies performed at the Institute, as well as cancer notifications in April 2020 point to a possibility of a delayed cancer diagnosis for some patients during the first surge of SARS-CoV-2 cases in Slovenia. | 2020-07-30 |
| 32726561 | A majority of centers curtailed diagnostic testing and a minority limited new starts of medical therapy. | 2020-07-30 |
| 32726792 | During the COVID-19 outbreak, the deferral of diagnostic and therapeutic procedures and a work backlog in every medical specialty are the natural consequences of reservation of resources for COVID-19 patients. | 2020-07-30 |
| 32727456 | Severe COVID-19 cases include severe and critical cases diagnosed according to the seventh edition of China’s COVID-19 diagnostic guidelines. […] Severe and critical COVID-19 cases were diagnosed according to the seventh edition of China’s COVID-19 diagnostic guidelines. | 2020-07-31 |
| 32727583 | The majority of head and neck surgical oncology from initial diagnosis and work up to surgical treatment and then follow-up involves aerosol generating medical procedures (AGMPs) which inherently put head and neck surgeons and practitioners at high risk for transmission of COVID19. | 2020-07-31 |
| 32727613 | For eligibility, healthcare workers with 18 years old or older working at least 3 days a week in a hospital with both negative SARS-CoV-2 polymerase chain reaction (PCR) assays and serological COVID-19 rapid diagnostic tests (RDT) are invited to participate. | 2020-07-31 |
| 32727662 | Moreover, the pandemic has also negatively impacted patients with liver disease who have not contracted COVID-19, since the reallocation of human and material resources to the care of patients with the virus has resulted in a decrease in the treatment, diagnosis and follow-up of patients with liver disease, which will surely have negative consequences in the near future. | 2020-07-31 |
| 32727828 | The COVID-19 pandemic caused by the new SARS-CoV-2 coronavirus has imposed severe challenges on laboratories in their effort to achieve sufficient diagnostic testing capability for identifying infected individuals. […] These results provide validation evidence for a sensitive and specific method for pandemic-scale automated molecular diagnostic testing for SARS-CoV-2. | 2020-07-31 |
| 32727861 | In this viewpoint, using Ghana, Malawi, South Africa, and Zimbabwe as examples of countries that have implemented different testing strategies, we argue that the implementation of sample pooling for rRT-PCR over antibody rapid diagnostic testing could have a greater impact in assessing disease burden. […] Sample pooling offers huge advantages compared to single test rRT-PCR, as it reduces diagnostic costs, personnel time, burnout, and analytical run times. | 2020-07-31 |
| 32728444 | Gastrointestinal complications in critically ill patients during the COVID-19 pandemic pose a diagnostic and treatment dilemma. | 2020-07-31 |
| 32728498 | The parameters that successfully model the pandemic are: the basic reproduction number R0, 4.4; a latent non-infectious period of 1.1. days followed by 4.6 days of the presymptomatic infectious period; the probability of developing severe symptoms, 0.01; the probability of being diagnosed when presenting severe symptoms of 0.6; the probability of diagnosis for cases with mild symptoms or asymptomatic, 0.001. | 2020-07-31 |
| 32728799 | Review of clinical examination, and whole-brain voxel-based analysis of 18F-FDG PET metabolism in comparison with healthy subjects (p voxel < 0.001, p-cluster < 0.05, uncorrected), of two patients with confirmed diagnosis of SARS-CoV-2 explored at the post-viral stage of the disease. | 2020-07-31 |
| 32729013 | To assess agreement on the etiology of abnormal liver biochemistries and diagnostic recommendations in COVID-19. […] Twenty hepatology consultations were reviewed by three senior hepatologists who provided a differential diagnosis and diagnostic recommendations. […] In COVID-19, elevated liver biochemistries present a diagnostic challenge and can often be monitored conservatively. | 2020-07-31 |
| 32729111 | The aim of this article is to review the possible indications of telemedicine in child neurology, starting out from the fact that we should never delay the diagnosis of something that can be treated, both at the present time and in an eventual situation of resurgence of the pandemic. | 2020-07-31 |
| 32729142 | Patients from 6 NYC-area hospital systems with known gynecologic cancer and a COVID-19 diagnosis were identified. […] Records for 121 patients with gynecologic cancer and COVID-19 were abstracted; the median age at the COVID-19 diagnosis was 64.0 years (interquartile range, 51.0-73.0 years). | 2020-07-31 |
| 32729263 | To describe the experience of implementing a deep learning-based computer-aided detection (CAD) system for the interpretation of chest X-ray radiographs (CXR) of suspected coronavirus disease (COVID-19) patients and investigate the diagnostic performance of CXR interpretation with CAD assistance. […] The diagnostic performance of radiologists with CAD assistance were evaluated based on two different reference standards: 1) real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) results for COVID-19 and 2) pulmonary abnormality suggesting pneumonia on chest CT. | 2020-07-31 |
| 32729264 | Early diagnosis is crucial for the management of the patients with COVID-19, but the gold standard diagnostic test for this infection, the reverse transcriptase polymerase chain reaction, has a low sensitivity and an increased turnaround time. […] In this scenario, chest computed tomography (CT) could play a key role for an early diagnosis of COVID-19 pneumonia. | 2020-07-31 |
| 32729288 | The most common symptoms at the time of diagnosis were fever (80.0%), cough (53.0%) and dyspnea (23.0%). | 2020-07-31 |
| 32729367 | The aim of our present review is to furnish brief details about the statistics, diagnosis, epidemiology, pathogenesis, prevention and treatment of COVID-19 to assist researchers and the society at large to come to grip with the deadly disease.HighlightsCumbersome outbreak of the novel Coronavirus Disease 2019 (COVID-19) became a pandemicAt June 19, 2020, as per WHO report 8,618,787 infected cases and 457,275 dead were recorded globallyMajor spread was found to be human to human transmissionsPeople with positive COVID-19 were infected with severe respiratory syndromeMore animal and clinical studies have to be done to overcome this pandemic. | 2020-07-31 |
| 32729460 | After a comprehensive approach, the diagnosis of COVID-19 and rhabdomyolysis was made. […] We performed a literature search for similar cases, discuss the potential mechanisms implied, and propose a diagnostic-therapeutic algorithm. | 2020-07-31 |
| 32729494 | Hence, a comprehensive review of strategies for COVID-19 diagnosis is essential in this existing global situation. […] The article systematically enlightens a clear overview of the clinically adopted techniques for the detection of COVID-19 including oligonucleotide-based molecular detection, Point-of-Care immunodiagnostics, radiographical analysis/sensing system, and newly developed biosensing prototypes having commercial viability. […] We believe that this review may provide scientists, clinicians and healthcare manufacturers valuable information regarding the most recent developments/approaches towards COVID-19 diagnosis. | 2020-07-31 |
| 32729548 | Early diagnosis of this viral disease is very important since it can prevent lots of mortalities and care consumption. […] The functional similarities between COVID-19 and COVID-2 in inducing acute respiratory syndrome lightened our mind to find a diagnostic mechanism based on early traces of mitochondrial ROS overproduction as lung cells’ dysfunctions induced by the virus. | 2020-07-31 |
| 32729549 | In particular, we cover and compare tests such as the CDC 2019-nCoV RT-PCR Diagnostic Panel, Cellex’s qSARS-CoV-2 IgG/IgM Rapid Test, and point-of-care tests such as Abbott’s ID NOW COVID-19 Test. | 2020-07-31 |
| 32729810 | Diagnostic performance and agreement with scores assigned by eight independent observers were measured using receiver operating characteristic (ROC) analysis, linearly-weighted kappa and classification accuracy. […] Conclusion CORADS-AI correctly identified COVID-19 positive patients with high diagnostic performance from chest CT exams, assigned standardized CO-RADS and CT severity scores in good agreement with eight independent observers and generalized well to external data. | 2020-07-31 |
| 32729811 | The World Health Organization (WHO) undertook the development of a rapid guide on the use of chest imaging in the diagnosis and management of COVID-19. […] The rapid guide includes three diagnosis recommendations and four management recommendations. | 2020-07-31 |
| 32730095 | In this detailed review, we have discussed the structure of SARS-CoV-2, essential proteins, its lifecycle, transmission, symptoms, pathology, clinical features, diagnosis, prevention, treatment and epidemiology of the disease. | 2020-07-31 |
| 32730110 | Literature related to the imaging of COVID-19 pneumonia, its findings and contribution to diagnosis and its differences from adults are limited in pediatric patients. […] Chest X-ray findings of 59 pediatric patients and chest CT findings of 22 patients with a confirmed diagnosis of COVID-19 pneumonia were evaluated retrospectively. […] In diagnosis, chest X-ray should be preferred, CT should be requested if there is a pathologic finding on radiography that merits further evaluation and if clinically indicated. | 2020-07-31 |
| 32730140 | Due to significant variations in the control strategies, which have been changing over time, and thanks to the introduction of detection technologies leading to faster confirmation of the SARS-CoV-2 infections, we made use of time-dependent contact and diagnosis rates to estimate when the effective daily reproduction ratio can fall below 1. […] The complementary parameter tuned is the transition rate of the symptomatic infected individuals to the quarantined class, a parameter δ I I connected with the time tI = 1/δIneeded to perform diagnostic tests. | 2020-07-31 |
| 32730210 | Moreover, the proposed method can be easily extended to other similar clinical applications such as computer-aided detection and diagnosis of pulmonary nodules in CT images, glaucoma lesions in Retina fundus images, etc. | 2020-07-31 |
| 32730212 | With this performance, the proposed algorithm could potentially aid radiologists with COVID-19 diagnosis from CAP, especially in the early stage of the COVID-19 outbreak. | 2020-07-31 |
| 32730214 | Tremendous efforts and resources have been invested in developing diagnosis, prognosis and treatment strategies to combat the disease. […] Although nucleic acid detection has been mainly used as the gold standard to confirm this RNA virus-based disease, it has been shown that such a strategy has a high false negative rate, especially for patients in the early stage, and thus CT imaging has been applied as a major diagnostic modality in confirming positive COVID-19. […] Despite the various, urgent advances in developing artificial intelligence (AI)-based computer-aided systems for CT-based COVID-19 diagnosis, most of the existing methods can only perform classification, whereas the state-of-the-art segmentation method requires a high level of human intervention. | 2020-07-31 |
| 32730215 | Segmentation of pneumonia lesions from CT scans of COVID-19 patients is important for accurate diagnosis and follow-up. | 2020-07-31 |
| 32730218 | Classification techniques can also be used to go through the large volume of references and allow researchers to save time on this part of their research. […] Text mining techniques can also help researchers calculate similarity indices and help them focus on the parts of the literature that are relevant for their research. | 2020-07-31 |
| 32730234 | CONCLUSIONS For proper diagnosis and treatment, patients and clinicians should be aware that COVID-19 may not present in the typical fashion of respiratory distress and fever. | 2020-07-31 |
| 32730368 | Timely diagnosis of COVID-19 is the key in containing the pandemic and breaking the chain of transmission. […] Pooling of RNA samples can reduce the time and expense, and can help expand diagnostic capabilities, especially during constrained supply of reagents and PCR kits for the diagnosis of SARS-CoV-2 infection. | 2020-07-31 |
| 32730589 | Given the absence of implemented therapies, new analysis, diagnosis, and therapeutics are of great importance. | 2020-07-31 |
| 32730619 | The median (IQR) time interval between COVID-19 diagnosis and CMR was 71 (64-92) days. […] None of these measures were correlated with time from COVID-19 diagnosis (native T1: r = 0.07; P = .47; native T2: r = 0.14; P = .15; hsTnT: r = -0.07; P = .50). […] In this study of a cohort of German patients recently recovered from COVID-19 infection, CMR revealed cardiac involvement in 78 patients (78%) and ongoing myocardial inflammation in 60 patients (60%), independent of preexisting conditions, severity and overall course of the acute illness, and time from the original diagnosis. | 2020-07-31 |
| 32730975 | General demographics, clinical status, mechanism of trauma, diagnosis, and treatment instituted were recorded. | 2020-07-31 |
| 32731090 | Delayed diagnosis and suboptimal cancer management due to the pandemic results in disease upstaging and has considerable impact cancer on specific death rates. | 2020-07-31 |
| 32731151 | Nucleic acid testing is the gold standard method for the diagnosis of coronavirus disease 2019 (COVID-19); however, large numbers of false-negative results have been reported. […] Nucleic acid detection and specific antibody (IgG and IgM) detection had similar positive rates, and their combination could improve the positive rate of COVID-19 detection, which is of great significance for diagnosis and epidemic control. | 2020-07-31 |
| 32731275 | Because viral RNA can be detected in fecal samples, some implications for clinical routine in diagnostic and therapeutic procedures are grown. | 2020-07-31 |
| 32731281 | Immunosuppressive therapy after kidney transplantation needs to be adapted upon diagnosis of COVID-19 depending on the severity of the initial presentation. | 2020-07-31 |
| 32731284 | Systematic follow-up, based on prudent pulmonary function testing, is warranted for the correct diagnosis, graduation and treatment of the underlying pathology at an early stage. | 2020-07-31 |
| 32731285 | Pulmonary sonography can be a valuable aid in the differential diagnosis of a variety of cardiopulmonary diseases, including patients with COVID-19. […] When COVID-19 is suspected, lung sonography is a valuable component of initial diagnosis when used systematically, performed hygienically and correctly. […] However, the findings of pulmonary sonography must be placed in the clinical context; sonography does not replace the gold standard of PCR diagnosis. | 2020-07-31 |
| 32732316 | Anecdotally, investigations for children with inflammatory bowel disease (IBD) have been restricted, resulting in diagnosis with no histological confirmation and potential secondary morbidity. […] For the month of April 2020, 20 tertiary paediatric IBD centres were invited to contribute data detailing: (1) diagnosis/management of suspected new patients with IBD; (2) facilities available; (3) ongoing management of IBD; and (4) direct impact of COVID-19 on patients with IBD. […] No patients with a presumed rather than confirmed diagnosis were started on anti-tumour necrosis factor (TNF) therapy.Most IBD follow-up appointments were able to occur using phone/webcam or face to face. […] Diagnostic IBD practice has been hugely impacted by COVID-19, with >50% of new diagnoses not having endoscopy. | 2020-08-01 |
| 32732325 | There is insufficient information about risk factors for COVID-19 diagnosis and adverse outcomes from low and middle-income countries (LMICs). […] We estimated the association between patients’ characteristics and COVID-19 diagnosis, hospitalisation and adverse outcome in Mexico. […] Their profile was stratified by COVID-19 diagnosis or not. […] This largest ever case series of COVID-19 patients identified risk factors for COVID-19 diagnosis, hospitalisation and adverse outcome. | 2020-08-01 |
| 32732333 | All patients had a confirmed diagnosis of COVID-19 pneumonia on computed tomography of the chest. | 2020-08-01 |
| 32732391 | Serologic evidence of previous infection in asymptomatic or PCR-negative patients suggests that current diagnostic screening strategies may be limited in their ability to detect acute infection. | 2020-08-01 |
| 32732512 | A final sample population of 355 patients was identified, and 78 of which had a known diagnosis of coronary artery disease. | 2020-08-01 |
| 32732664 | We surveyed faculty about their experience during the early weeks of adapting to these new instructional techniques. | 2020-08-01 |
| 32733566 | The aim of this work is to present a protocol to standardize the outpatient oral surgery activities through remote triage, diagnostic tests, protections, and precautions that allow to provide care while minimizing risk for both patients and surgeons. | 2020-08-01 |
| 32733625 | This case advocates regular wake-up calls in Coronavirus disease 2019 patients for neurological (radiological) evaluation to provide rapid diagnosis and a therapeutic window for fulminant central nervous system complications. | 2020-08-01 |
| 32733707 | Given the shortage of diagnostic kits in many countries and very high sensitivity of computed tomography (CT) for diagnosis of COVID-19 in clinically suspicious patients, the chest CT has been implemented among the primary initial methods of diagnosis before the confirmatory laboratory tests. […] This report summarizes chest CT findings of COVID-19 patients to facilitate diagnosis and reviews a list of necessary precautions and safety measures for diagnostic and interventional radiology personnel. | 2020-08-01 |
| 32733734 | A diagnosis of intra-amniotic infection is typically made based on clinical criteria, including maternal intrapartum fever and one or more of the following: maternal leukocytosis, purulent cervical drainage, or fetal tachycardia. […] The diagnosis can also be made in patients with an isolated fever of 39°C, or greater, without any other clinical risk factors present. […] In this report, we detail a case of a newborn born to a mother with a clinical diagnosis of intra-amniotic infection with maternal fever and fetal tachycardia, who was then found to be SARS-CoV-2 positive on testing. | 2020-08-01 |
| 32733775 | Diagnostic instruments are rapidly evolving. | 2020-08-01 |
| 32733908 | Differential diagnosis is challenging and the exclusion of other life-threatening diseases has major caveats. […] In the era of this pandemic, diagnosis of other life-threatening diseases might delay treatment. […] The Food and Drug Administration has recently authorized the first antibody-based test for COVID-19; however, RT-PCR of nasopharyngeal or oropharyngeal swabs remains the recommended test for diagnosis. | 2020-08-01 |
| 32733982 | A cross sectional study was designed to evaluate patients admitted for vertebral fractures with diagnosis of COVID-19 infection on February and March 2020. […] In three cases the COVID diagnosis was made the day after arrival and in others after 10, 14 and 35 days. […] Proper diagnosis of COVID-19 is the keystone to protect both patients and health care providers. | 2020-08-01 |
| 32733985 | During the course of novel coronavirus pandemic ,Shariati hospital in Tehran , as a tertiary center in both orthopedic trauma and COVID-19 , we detected 7 cases with definite diagnosis of COVID-19 and concomitant emergent orthopedic problem.This paper represents considerations and special issues in managing and decision making in these patients. | 2020-08-01 |
| 32734407 | The diagnosis, grading of severity and clinical management of COVID-19 patients complied to the guideline and clinical protocol issued by the China National Health Commission. | 2020-08-01 |
| 32734526 | In addition, the diagnosis of ACS may have been difficult due to possible underlying myocarditis or other clinical entities. | 2020-08-01 |
| 32734624 | In ED patients who underwent CTPA for suspected PE, COVID-19 was not associated with an increased probability of PE diagnosis. | 2020-08-01 |
| 32734626 | COVID-19 pandemic affected the diagnosis and management of many diseases including melanoma. […] In this study, we aimed to provide a review focused on the diagnosis and management of melanoma in the era of COVID-19. […] The current guidelines recommend that surgical interventions for new diagnosis of invasive primary melanoma, patients with postoperative complications, wide resection and sentinel lymph node biopsy for newly diagnosed T3-T4 melanoma, and planned surgical procedures for patients in neo-adjuvant trials should be prioritized. | 2020-08-01 |
| 32734784 | We discuss telemedicine examination techniques for commonly encountered spine conditions. […] Techniques to evaluate gait, the cervical spine, the lumbar spine, adult spinal deformity patients, and adolescent scoliosis patients via telemedicine are described. | 2020-08-01 |
| 32734857 | The case highlights the importance of strict monitoring of water and air systems immediately before reopening business or public sector buildings, and the need to consider Legionella infections among the differential diagnosis of respiratory infections after lockdown due to the ongoing COVID-19 pandemic. | 2020-08-01 |
| 32735050 | Computer tomography angiogram and echocardiography confirmed the diagnosis. | 2020-08-01 |
| 32735448 | Extension of prophylaxis and adaptation of diagnostic criteria should be considered. | 2020-08-01 |
| 32735457 | The National Institute for Public Health of the Netherlands published a report for guidance on diagnosis, prevention and treatment of thromboembolic complications in COVID-19 with a new vascular disease concept. […] The analysis of all available current medical, laboratory and imaging data on COVID-19 confirms that symptoms and diagnostic tests can not be explained by impaired pulmonary ventilation. | 2020-08-01 |
| 32735546 | To achieve such objectives, we applied natural language processing techniques to identify drugs and linked entities (eg, disease, gene, protein, chemical compounds). | 2020-08-01 |
| 32735699 | (…) Small increments in clinical improvement will still be possible in the future, but for the most part, the potential for major advancement using these techniques has been exhausted’ (Frank Hanley, MD; Stanford). | 2020-08-01 |
| 32735842 | In this observational study, adult patients with a confirmed COVID-19 diagnosis, who were admitted to hospital in Germany between Feb 26 and April 19, 2020, and for whom a complete hospital course was available (ie, the patient was discharged or died in hospital) were included in the study cohort. | 2020-08-01 |
| 32736393 | It is estimated that around 28 million surgeries will be postponed or canceled worldwide as a result of this pandemic, causing a delay in the diagnosis and treatment of more than 2 million cancer cases. | 2020-08-01 |
| 32736592 | Randomised, parallel arm, open-label, adaptive platform Phase 2/3 trial of potential disease modifying therapies in patients with late stage 1/stage 2 COVID-19-related disease, with a diagnosis based either on a positive assay or high suspicion of COVID-19 infection by clinical, laboratory and radiological assessment. | 2020-08-02 |
| 32736597 | Since up to date reduced evidence about COVID-19 infection epidemiology, the continuous update of diagnostic and therapeutic approaches, the sample size estimation could be updated after a one third of population will be recruited and eventually modified according to a substantial protocol amendment. | 2020-08-02 |
| 32736821 | These findings reinforce the value of Geriatric Assessment to develop strategies to adapt diagnostic and therapeutic decision-making and to optimize care for elderly patients in the event of a new epidemic outbreak. | 2020-08-02 |
| 32736852 | And second, the effects of COVID-19 pathophysiology on obstetrical patients (e.g., testing and diagnosis, best use of modified obstetric early warning systems, approach to maternal respiratory compromise, collaboration with critical care teams, and potential need for cardiopulmonary resuscitation). | 2020-08-02 |
| 32737467 | S-protein derivatives are components of vaccine candidates and diagnostic assays, as well as tools for research into the biology and immunology of SARS-CoV-2. | 2020-08-02 |
| 32737472 | A positive association between higher per-capita income and COVID-19 diagnosis was identified. | 2020-08-02 |
| 32737681 | A systematic screening of a drug library (having drugs and diagnostic agents which are approved by FDA or other world authorities) and the Asinex BioDesign library was carried out using pharmacophore and sequential conformational precision level filters using the Schrodinger Suite. | 2020-08-02 |
| 32737746 | Most diagnoses were probable as the accurate diagnosis of opportunistic fungal infections remains challenging in resource-poor settings. | 2020-08-02 |
| 32737747 | Aspergillus and Candida infections in COVID-19 patients will require early detection by a comprehensive diagnostic intervention (histopathology, direct microscopic examination, culture, (1,3)-β-D-glucan, galactomannan, and PCR-based assays) to ensure effective treatments. […] We suggest it is prudent to assess the risk factors, the types of invasive mycosis, the strengths and limitations of diagnostic methods, clinical settings, and the need for standard or individualized treatment in COVID-19 patients. | 2020-08-02 |
| 32737838 | Strict ad hoc hygiene protocol for Covid-19 pandemic avoids diagnostic-therapeutic delay and lengthening of waiting lists. | 2020-08-02 |
| 32738040 | Early adrenal axis testing, as well as directed imaging, is crucial for immediate diagnosis and treatment. | 2020-08-02 |
| 32738164 | This pathophysiological mechanism was clearly demonstrated by intracoronary imaging techniques (optical coherence tomography) and invasive vasospasm test. | 2020-08-02 |
| 32738255 | Several techniques to detect SARS-CoV-2 infection have been established, mainly based on counting infected cells by staining plaques or foci, or by quantifying the viral genome by PCR. | 2020-08-02 |
| 32738287 | Patients with a positive previous psychiatric diagnosis showed increased scores on most psychopathological measures, with similar baseline inflammation. | 2020-08-02 |
| 32738407 | The objective of this study was to investigate the clinical usefulness of d-dimer in excluding a diagnosis of deep vein thrombosis (DVT) in patients with coronavirus disease (COVID-19) infection, potentially limiting the need for venous duplex ultrasound examination. […] These groups were then compared to determine the value of d-dimer in establishing this diagnosis. | 2020-08-02 |
| 32738464 | The goal of this study was to assess chest computed tomography (CT) diagnostic accuracy in clinical practice using RT-PCR as standard of reference. […] The diagnostic performance of CT was evaluated according to sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and diagnostic accuracy, considering RT-PCR as the reference standard. […] In our experience, in a context of high pre-test probability, CT scan shows good sensitivity and a consistently higher specificity for the diagnosis of COVID-19 pneumonia than what reported by previous studies, especially when clinical and epidemiological features are taken into account. | 2020-08-02 |
| 32739381 | We assessed how altered diagnostic processes and criteria for gestational diabetes mellitus (GDM) recommended by the United Kingdom (UK), Canada and Australia for use during the COVID-19 pandemic would affect both GDM frequency and related adverse outcomes. […] The modifications in GDM diagnosis proposed for the UK, Canada and Australia result in differing reductions of GDM frequency. | 2020-08-03 |
| 32739398 | This systematic review included cohort studies, case series, and case reports of pregnant women who received a coronavirus disease 2019 diagnosis using severe acute respiratory syndrome coronavirus 2 viral RNA test and had reported data regarding the testing of neonates or fetuses for severe acute respiratory syndrome coronavirus 2 immediately after birth and within 48 hours of birth. | 2020-08-03 |
| 32740498 | From 9 March to 15 April, we performed: a total of 21 cardiac surgeries, 4 diagnostic catheterizations, 3 CT scans, and 2 CMR. […] In three cases with prenatal diagnosis, the birth was scheduled. | 2020-08-03 |
| 32740678 | This review describes various techniques of machine learning that have been used in the past in the prediction, detection and management of infectious diseases, and how these tools are being brought into the battle against COVID-19. | 2020-08-03 |
| 32740817 | This study proposes a clinical computer-aided diagnosis (CAD) system using CT features to automatically discriminate COVID-19 from non-COVID-19 pneumonia patients. […] It can be considered an adjunct tool by the radiologists during the current COVID-19 pandemic to make an accurate diagnosis. […] • The AUC, sensitivity, specificity, and accuracy obtained by radiologist diagnosis are 0.879, 87.10%, 88.71%, and 87.90%, respectively. | 2020-08-03 |
| 32741085 | To assess whether olfactory dysfunction could be used as a diagnostic marker for COVID-19 positivity and aid public health approaches in tackling the current outbreak. | 2020-08-03 |
| 32741393 | Given national shortages of testing supplies, personal protective equipment, and other hospital resources, diagnostic stewardship is necessary to aid in resource management. | 2020-08-04 |
| 32741394 | A diagnosis of Brugada pattern in paediatric or adolescent patients is rare. | 2020-08-04 |
| 32741802 | To assess prognosis or dynamic change from initial diagnosis until recovery of the patients with moderate coronavirus disease (COVID-19) pneumonia using chest CT images. | 2020-08-04 |
| 32742318 | Chest radiological imaging paired with artificial intelligence (AI) can offer significant advantages in diagnosis of novel coronavirus infected patients. […] To this end, transfer learning techniques are used for overcoming the limitations emanating from the lack of relevant big datasets, enabling specialized models to converge on limited data, as in the case of X-rays of COVID-19 patients. | 2020-08-04 |
| 32742701 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; initially named as 2019-nCoV) is responsible for the recent COVID-19 pandemic and polymerase chain reaction (PCR) is the current standard method for its diagnosis from patient samples. […] This study conducted a reassessment of published diagnostic PCR assays, including those recommended by the World Health Organization (WHO), through the evaluation of mismatches with publicly available viral sequences. […] A comprehensive bioinformatics approach for in silico inclusivity evaluation of PCR diagnostic assays of SARS-CoV-2 was validated using freely available software programs that can be applied to any diagnostic assay of choice. | 2020-08-04 |
| 32742705 | The combination of regular testing with strict household quarantine, which was not analysed in their models, has remarkable power to reduce transmission to the community from other household members as well as providing earlier diagnosis and facilitating rapid contact tracing. | 2020-08-04 |
| 32742815 | Overall, the exploration of the diversity of these isolates, mutational hotspots and pan-genome will shed light on the evolution and pathogenicity of SARS-CoV-2 and help in developing putative methods of diagnosis and treatment. | 2020-08-04 |
| 32742881 | This case not only highlights the utility of SARS-CoV-2 IgG in the diagnosis of COVID-19 when RT-PCR is negative but suggests MIS-C may be a post-infectious immune-mediated process. | 2020-08-04 |
| 32742969 | However, early diagnosis and hospitalization with adequate care may be important variables for better survival. | 2020-08-04 |
| 32742970 | This study inspires optimism that proper diagnosis, establishment of effective inclusion and exclusion criteria, ensuring application of proper SoC with drugs available in Bangladesh may be a practical option for management of COVID-19 in the country. | 2020-08-04 |
| 32742978 | In this review, we summarize the clinical characteristics of COVID-19 induced AKI by focusing on its epidemiology, pathogenesis, clinical diagnosis, and treatment. | 2020-08-04 |
| 32743705 | The diagnostic distribution of patients (n = 414) eligible for the study was as follows: juvenile idiopathic arthritis (JIA) (n = 243, 58.7%), autoinflammatory diseases (n = 109, 26.3%), connective tissue diseases (n = 51, 12.3%), and vasculitis (n = 11, 2.7%). | 2020-08-04 |
| 32743882 | A telephone survey of heart (n = 69) and lung (n = 41) transplant patients and a group of controls (n = 41) was conducted concerning personal hygiene before and after the outbreak; the impact on subjective expectations regarding graft outcome; symptoms possibly associated with SARS-CoV-2 infection; and diagnosis of COVID-19. | 2020-08-04 |
| 32744638 | Weaknesses include uncertainties regarding the management of COVID-19 affected asymptomatic patients, the suboptimal accuracy of diagnostic tests for the disease, the nebulous prospective regarding the duration of the pandemic and the additional costs. | 2020-08-04 |
| 32744706 | Early screening and early diagnosis play key roles in prevention and management of the epidemic. […] We here show the advantages of this kind of remote ultrasound scan, which could become a method for the diagnosis and assessment of COVID-19. | 2020-08-04 |
| 32745068 | Diagnostic specificity, sensitivity, agreement between assays and ROC curve-derived optimized thresholds were determined. […] Diagnostic sensitivity for samples collected ≥14 days after PCR-positivity was 97.0, 89.4 and 95.5% using the Siemens, Roche and Euroimmun assay, respectively. | 2020-08-04 |
| 32745249 | As such, they may not be particularly helpful as an aide to diagnosis. | 2020-08-04 |
| 32745548 | Quercetin could be shown to interact with 3CLpro using biophysical techniques and bind to the active site in molecular simulations. | 2020-08-04 |
| 32745596 | Community-acquired co-infection at COVID-19 diagnosis was uncommon (31/989, 3.1%) and mainly caused by Streptococcus pneumoniae and Staphylococcus aureus. […] A total of 51 hospital-acquired bacterial superinfections, mostly caused by Pseudomonas aeruginosa and Escherichia coli, were diagnosed in 43 patients (4.7%), with a mean (SD) time from hospital admission to superinfection diagnosis of 10.6 (6.6) days. […] Co-infection at COVID-19 diagnosis is uncommon. | 2020-08-04 |
| 32745627 | The ongoing COVID-19 pandemic continues to impose demands on diagnostic screening. […] Six different RT-qPCR alternatives were evaluated for SARS-CoV-2/COVID-19 diagnosis based on standard RNA extractions. | 2020-08-04 |
| 32745693 | The steering committee prepared 10 working packages addressing significant clinical questions from diagnosis to surgery. […] Overall, the expert panel agreed on 28 consensus statements that can be used to overcome many of the clinical and technical areas of uncertainty ranging from diagnosis to therapeutic planning and treatment during the COVID-19 pandemic. | 2020-08-04 |
| 32745794 | Depression, anxiety, and PTSD symptoms, as well as COVID-19-related concerns, sleep problems, and quality of life were compared across the following pre-existing mental health groups: 1) no diagnosis, 2) suspected diagnosis, 3) diagnosed and untreated, and 4) diagnosed and treated. […] Compared to those without a diagnosis, the likelihood of scoring above the clinical threshold for those with a diagnosis - whether treated or not - was more than six-fold for depression, and four-to six-fold for anxiety and PTSD. […] Individuals with a suspected diagnosis were 3 times more likely to score above the clinical threshold for depression and anxiety and 2 times more as likely to score above this threshold for PTSD compared to those with no diagnosis. […] We also present higher levels of COVID-19-related worry and grief, poorer sleep, and poorer reported health-related quality of life among those with either a suspected or reported mental health diagnosis. […] Findings provide evidence of vulnerability among individuals with a mental health diagnosis or suspected mental health concerns during the initial weeks of the COVID-19 pandemic. | 2020-08-04 |
| 32746195 | This is particularly true for COVID-19 diagnostic. | 2020-08-04 |
| 32746805 | CT plays a crucial role in the early diagnosis and monitoring of changes in COVID-19. | 2020-08-05 |
| 32746913 | Updated versions of diagnosis and treatment guideline for novel coronavirus (COVID-19) patients have been issued, and traditional Chinese herbal medicine has been recommended as a treatment. | 2020-08-05 |
| 32746922 | Understanding the immune processes related to COVID-19, and other similar infections, could help identify diagnostic markers and therapeutic targets. | 2020-08-05 |
| 32747155 | Up to 47.40% of patients with COVID-19 diagnosis were also reported with a comorbidity, with hypertension being the most frequent (20.12%). | 2020-08-05 |
| 32747185 | Hospital staff who had recovered from mild forms of PCR-confirmed SARS-CoV-2 infection were tested for anti-SARS-CoV-2 antibodies using two assays: a rapid immunodiagnostic test (99.4% specificity) and the S-Flow assay (~99% specificity). […] The rapid immunodiagnostic test detected antibodies in 153 (95.6%) of the samples and the S-Flow assay in 159 (99.4%), failing to detect antibodies in one sample collected 18 days after symptom onset (the rapid test did not detect antibodies in that patient). […] This finding supports the use of serologic testing for the diagnosis of individuals who have recovered from SARS-CoV-2 infection. | 2020-08-05 |
| 32747400 | Specificity was evaluated using samples from routine diagnostic testing/blood donors collected before December 2019 and thus deemed negative for SARS-CoV-2-specific antibodies. | 2020-08-05 |
| 32748035 | In recent years, many new technologies have been explored for diagnosis, prevention, and treatment of viral infections. | 2020-08-05 |
| 32748211 | During the COVID-19 outbreak, patients with sudden loss of smell should initiate social distancing and home isolation measures and be tested for SARS-CoV-2 diagnostic test when available. | 2020-08-05 |
| 32748244 | This data includes previously used strategies against infectious disease, recent clinical trials and FDA-approved diagnostic and treatment strategies. […] The results demonstrate various conventional as well as potentially advanced in vitro diagnostic approaches (IVD) for the diagnosis of COVID-19. […] It is concluded that the exploration of a range of diagnostic and treatment strategies for the management of COVID-19 is the need of the hour. | 2020-08-05 |
| 32748481 | Secondary outcomes included the average daily number of presentations for pre-specified subgroups defined by triage category and diagnosis. […] Attendance was lower than anticipated for all triage categories (especially category 5 [IRR 0.51, 95% CI 0.44-0.59]) and diagnostic groups (including circulatory problems [IRR 0.62, 95% CI 0.50-0.76] and injury [IRR 0.58, 95% CI 0.53-0.63]). | 2020-08-05 |
| 32749151 | Transthoracic echocardiography has demonstrated diagnostic, prognostic and therapeutic utility. | 2020-08-05 |
| 32749247 | Timely diagnosis and follow-up of pulmonary involvement need a comprehensive imaging strategy, which includes standard chest X-ray, chest computed tomography and lung ultrasound (LUS). | 2020-08-05 |
| 32749557 | After the first COVID-19 diagnosis in the region, emergency department visit volume decreased by 30% compared with the same period in 2019 (p = 0.0012). | 2020-08-05 |
| 32749593 | Reverse transcription-polymerase chain reaction (RT-PCR) is an essential method for specific diagnosis of SARS-CoV-2 infection. | 2020-08-05 |
| 32749634 | Among patients with COVID-19, a higher proportion have an underlying diagnosis of cancer than seen in the general population. […] The early months of the pandemic saw a decrease in cancer screening and diagnosis, as well as postponement of standard treatments, which could lead to excess deaths from cancer in the future. | 2020-08-05 |
| 32749697 | COVID-19 has had a significant impact on the number of patients undergoing breast cancer prevention, screening, diagnosis, and treatment. | 2020-08-05 |
| 32749709 | Two parameters (monocyte count and percentage of basophils) were combined to clarify the diagnostic efficacy of COVID-19 and influenza and the area under the curve was found to be 0.772. […] The diagnostic formula developed by this study will be of benefit for physicians in the differentiation of COVID-19 and influenza. | 2020-08-05 |
| 32749806 | An epidemic consists of several stages, each with its own focus with respect to source and contact tracing and diagnostic testing. […] An epidemic of this magnitude is usually associated with common healthcare challenges, for example limited availability of diagnostic resources and personal protective equipment. | 2020-08-05 |
| 32749914 | This review highlights the current state of knowledge on the viral replication and pathogenicity, diagnostic and therapeutic strategies, and management of COVID-19. | 2020-08-05 |
| 32750000 | The epidemiology and clinical and laboratory features of pregnant women with COVID-19 were diverse and atypical, which increased the difficulty of diagnosis. | 2020-08-05 |
| 32750012 | We will implement daily supportive text messaging as a way of reducing and managing anxiety and depression related to cancer diagnosis and treatment in Alberta, Canada. […] Alberta residents with a cancer diagnosis and the close relatives of those dealing with a cancer diagnosis can self-subscribe to the Text4Hope-Cancer Care program by texting “CancerCare” to a dedicated text number. | 2020-08-05 |
| 32750184 | To evaluate the diagnostic and prognostic performance of alternative diagnostic strategies to oral glucose tolerance tests, including random plasma glucose, fasting plasma glucose and HbA1c , during the COVID-19 pandemic. […] Gestational diabetes diagnosis was significantly associated with random plasma glucose at 12 weeks [area under the receiver-operating characteristic curve for both criteria 0.81 (95% CI 0.79-0.83)], fasting plasma glucose [National Institute of Health and Clinical Excellence: area under the receiver-operating characteristic curve 0.75 (95% CI 0.65-0.85); International Association of Diabetes and Pregnancy Study Groups: area under the receiver-operating characteristic curve 0.92 (95% CI 0.85-0.98)] and HbA1c at 28 weeks’ gestation [National Institute of Health and Clinical Excellence: 0.83 (95% CI 0.75-0.90); International Association of Diabetes and Pregnancy Study Groups: 0.84 (95% CI 0.77-0.91)]. | 2020-08-05 |
| 32750190 | In the current study, we performed a literature review on coronavirus outbreak to summarise details about the pathogenesis, epidemiology, diagnosis and the management strategies for the disease control. | 2020-08-05 |
| 32750694 | We also discuss the direct cytopathic effect of the virus on renal tissue and extracorporeal blood purification techniques that can prevent kidney damage or reduce acute kidney injury progression. | 2020-08-05 |
| 32750752 | However, new symptoms can provide diagnostic and testing criteria for patients with no other clinical presentation, especially in older children. | 2020-08-05 |
| 32750931 | Our findings shed light on the importance of using public opinions and suitable computational techniques to understand issues surrounding COVID-19 and to guide related decision-making. | 2020-08-06 |
| 32750973 | Fast and accurate diagnosis is essential for the efficient and effective control of the COVID-19 pandemic that is currently disrupting the whole world. […] Despite the prevalence of the COVID-19 outbreak, relatively few diagnostic images are openly available to develop automatic diagnosis algorithms. | 2020-08-06 |
| 32751106 | To control the COVID-19 pandemic and prevent its resurgence in areas preparing for a return of economic activities, a method for a rapid, simple, and inexpensive point-of-care diagnosis and mass screening is urgently needed. […] The assay involves simple equipment and techniques and low cost, without the need for expensive qPCR machines, and the result, indicated by color change, is easily interpreted by naked eyes. […] This inexpensive, highly sensitive and specific COVID-19-LAMP assay can be useful for rapid deployment as mobile diagnostic units to resource-limiting areas for point-of-care diagnosis, and for unlimited high-throughput mass screening at borders to reduce cross-regional transmission. | 2020-08-06 |
| 32751866 | In this study, we monitored the digital ecosystems during March and April 2020, and we obtained a sample of 106,261 communications through the analysis of APIs and Web Scraping techniques. | 2020-08-06 |
| 32752043 | In response to the urgent need of diagnostic tools, several lab-based and biosensing techniques have been proposed so far. […] Alternative to swab-based techniques, lateral flow point-of-care immunoassays are already commercially available for the analysis of blood samples. | 2020-08-06 |
| 32753076 | This demands a wide index of suspicion for prompt diagnosis of SARS-CoV-2 to prevent further complications and mortality. | 2020-08-06 |
| 32753137 | Only studies involving patients with diagnostic-confirmed COVID-19 infection were included. | 2020-08-06 |
| 32753143 | There were no statistically significant differences in age (P=.95), sex (P=.10), diagnosis (P=.26), or regional variations (P=.08) in activation volumes. | 2020-08-06 |
| 32753146 | In addition to photographs, accompanying videos are included to facilitate and demonstrate specific physical examination techniques that the patient can self-perform. | 2020-08-06 |
| 32753638 | Individuals with spinal cord injury (SCI) develop systemic physiological changes that could increase the risk of severe evolution of coronavirus disease 2019 (COVID-19) and result in atypical clinical features of COVID-19 with possible delay in both diagnosis and treatment. | 2020-08-06 |
| 32754005 | We show that CDSS may be used to analyze physiologic data for clinical event recognition and automated diagnosis, and we also highlight future research avenues for hospital CDSS. | 2020-08-06 |
| 32754224 | The therapeutic benefits of Cold‒Damp Plague Formula (CDPF) against COVID-19, which was used to treat “cold‒dampness stagnation in the lung” in Trial Versions 6 and 7 of the “Diagnosis and Treatment Protocol for COVID-19”, have been demonstrated, but the effective components and their mechanism of action remain unclear. | 2020-08-06 |
| 32754375 | Chest radiography (or chest X-ray, CXR) and CT are important for the imaging diagnosis of the coronavirus pneumonia (COVID-19). | 2020-08-06 |
| 32754377 | The cases described would be useful in aiding early diagnosis, limiting and improving the management of serious complications for patients, and allowing rapid and appropriate treatment. | 2020-08-06 |
| 32754385 | A diagnosis of SIADH was made due to COVID-19 pneumonia. | 2020-08-06 |
| 32754437 | Differential diagnosis can be challenging since influenza may present with similar symptoms. | 2020-08-06 |
| 32754447 | We found that 36% of patients had anxiety (HADS-A), 31% depression (HADS-D), and 43% were above the cut-off for the HADS-General Scale; 36% fulfilled the diagnostic criteria for post-traumatic stress disorder (PTSD). | 2020-08-06 |
| 32754570 | Studies on the development of in vitro diagnostic tests, vaccines, and drug re-purposing are being carried out in this field. […] This review focuses on recent advancements in the field of development of diagnostic tests, vaccines, and treatment approaches for COVID-19. | 2020-08-06 |
| 32754600 | These issues pose great challenges to disease diagnosis and epidemic control. […] Through associating infection symptoms with the transmission routes of virus and the patient course of the disease, we expect to provide guidelines for clinical diagnosis and the basis for suppressing the spread of the virus and antiviral treatment. | 2020-08-06 |
| 32754756 | This study reports how COVID-19 has spread in South Korea and examines the effects of rapid widespread diagnostic testing on the spread of the disease in the early epidemic phase. | 2020-08-06 |
| 32754962 | To determine if there has been a decrease in skin cancer diagnosis in the UK in the COVID-19 era, we analysed data from the Northern Cancer Network from 23 March 2020 to 23 June 2020 and compared it with the same period in 2019 (pre-COVID). | 2020-08-06 |
| 32754967 | Currently, detection of the RNA from the novel coronavirus SARS-CoV-2 is the gold standard for establishing a COVID-19 diagnosis. […] Overall, the kit is potentially useful for SARS-CoV-2 diagnostic testing and meets the verification requirements. […] This study aims to develop an improved SARS-CoV-2 verification framework compared with traditional molecular diagnostic methods, given the urgency of implementing new assays in clinical laboratories. | 2020-08-06 |
| 32755198 | Although chest CT is the standard imaging modality in early diagnosis and management of coronavirus disease (COVID-19), the use of lung ultrasound (US) presents some advantages over the use of chest CT and may play a complementary role in the workup of COVID-19. | 2020-08-07 |
| 32755212 | The constellation of imaging findings in the setting of COVID-19 may alert pediatric radiologists to the diagnosis of MIS-C prior to rapid deterioration of patients. | 2020-08-07 |
| 32755256 | Validation of the exam as a diagnostic tool will be a crucial next step in studying the impact of telemedicine. | 2020-08-07 |
| 32755524 | We have been introduced to “Coronavirus Disease 2019 (COVID-19)” disease with high mortality and transmission rate caused by a novel human coronavirus, in December 2019 and the microbiological diagnosis of the infection has been in the center of the focus to control the pandemic. […] The most commonly used and reliable test for diagnosis of COVID-19 is reverse-transcribed polymerase chain reaction (RT-PCR) performed by using nasopharyngeal swabs or other respiratory tract specimens. […] There is an increasing interest in the use of SARS-CoV-2 antibody tests both for the diagnosis and public health surveillance. […] However, the antibody tests should not be used as the sole test for diagnosis and case management. […] It was shown that clinical sensitivity of the diagnostic approach increases when RNA and total antibody tests were integrated as co-tests, especially after the second week of the disease. […] In this review article, the information and data obtained until today about SARS-CoV-2 and its microbiological diagnosis have been discussed. | 2020-08-07 |
| 32755529 | This has necessitated the exploration of alternative diagnostic options to alleviate supply chain issues.Aim. […] With a simplified workflow, The N1 gene Single Tube Optigene LAMP assay (N1-STOP-LAMP) is a powerful, scalable option for specific and rapid detection of SARS-CoV-2 and an additional resource in the diagnostic armamentarium against COVID-19. | 2020-08-07 |
| 32755673 | The present review presents a comprehensive overview of COVID-19 and SARS-CoV-2, with emphasis on the role of animals and their jumping the cross-species barriers, experiences learned from SARS- and MERS-CoVs, zoonotic links, and spillover events, transmission to humans and rapid spread, and highlights the new advances in diagnosis, vaccine and therapies, preventive and control measures, one health concept along with recent research developments to counter this pandemic disease. | 2020-08-07 |
| 32755848 | Tuberculosis (TB) still continues to be endemic in various regions of the world, including in India and needs surveillance, clinical assessment, testing, contact tracing, confirmation of diagnosis with supervised or in-supervised treatment regimens for an effective eradication. | 2020-08-07 |
| 32756107 | As early diagnosis is fundamental to control the spread of COVID-19 infection, we emphasize that anosmia identified in febrile cases during the COVID-19 epidemic may be a symptom indicative of the disease. | 2020-08-07 |
| 32756149 | According to the guideline for the diagnosis and treatment of 2019 novel coronavirus infected pneumonia (Trial 4th Edition), COVID-19 was diagnosed, based on the real-time RT-PCR test of SARS-CoV-2. | 2020-08-07 |
| 32756215 | The diagnosis was confirmed by a real-time reverse transcription polymerase chain reaction test for SARS-CoV-2. | 2020-08-07 |
| 32756585 | Self-collection of diagnostic specimens at home offers an avenue to allow people to test for SARS-CoV-2 infection or immune response without traveling to a clinic or laboratory. […] 153 US adults were enrolled in a study of the willingness and feasibility of patients to self-collect three diagnostic specimens (saliva, oropharyngeal swab (OPS) and dried blood spot (DBS) card) while observed by a clinician through a telehealth session. | 2020-08-07 |
| 32756602 | Clinicians and laboratories should feel better informed and assured using COPAN ESwabs ® 480C to help in the diagnosis of COVID-19. | 2020-08-07 |
| 32756614 | Np is one of the most abundant structural proteins and it serves as a diagnostic marker for the accurate and sensitive detection of COVID-19. […] The results demonstrate that aptamers are powerful molecular tools for virus detection, diagnosis, and antiviral therapy. | 2020-08-07 |
| 32756734 | COVID-19 diagnosis was confirmed by SARS-CoV-2-RT-PCR in nasal swabs. […] After diagnosis, neurologists were involved in the treatment. | 2020-08-07 |
| 32756915 | Commercially available serologic tests for anti-SARS-CoV-2 antibodies are being performed. | 2020-08-07 |
| 32757278 | The aim of this study was to evaluate the applicability of bedside ultrasonography for the diagnosis of deep venous thrombosis (DVT) in patients infected with corona virus disease 2019 (COVID-19) with and without treatment with low molecular weight heparin (LMWH). | 2020-08-07 |
| 32757497 | In this study, administration of HCQ <5 days from diagnosis (odds ratio: 0.111, 95% confidence interval: 0.034 - 0.367, P = 0.001) was the only protective factor for prolonging of viral shedding in COVID-19 patients. | 2020-08-07 |
| 32757500 | This retrospective case series included 10 patients with a clinically and laboratory confirmed diagnosis of severe COVID-19 pneumonia who had received RDV for 5 days (n = 5) or 10 days (n = 5) in the Phase III clinical trial of RDV (GS-US-540-5773) conducted by Gilead Sciences. | 2020-08-07 |
| 32757745 | AuNPs increase the efficacy of biomedical applications in diagnostic treatments for infectious diseases, by targeting or labeling target cells/bioactive compounds. […] However, it is imperative to develop the regimens for more accurate diagnostic tools, preventive care and effective therapy. […] This manuscript critically reviews the rampant future of AuNPs in the diagnosis and treatment of the most important diseases, such as cancer and viruses of respiratory system. | 2020-08-08 |
| 32757995 | The diagnosis was confirmed by the validated University of Pennsylvania Smell Identification Test (UPSIT) in 3. | 2020-08-08 |
| 32758014 | Currently, with broader availability of polymerase chain reaction for disease diagnosis, CT is mainly used for the identification of complications and other defined clinical indications in hospitalized patients. […] In addition to understanding the imaging findings for the diagnosis of the disease, it is important to understand the growing set of tools provided by artificial intelligence. | 2020-08-08 |
| 32758307 | There was a 55 per cent decrease in referrals but diagnostic yield rose from 2.9 per cent in January to 8.06 per cent in April. | 2020-08-08 |
| 32758313 | Diagnostic testing for the novel coronavirus is an important tool to fight the coronavirus disease (Covid-19) pandemic. | 2020-08-08 |
| 32758871 | It is hoped that our model stimulates review of current diagnostic and therapeutic intervention protocols, particularly with respect to early anticoagulation, vasodilatation and revision of ventilatory support choices. | 2020-08-08 |
| 32759252 | Viral dynamic data and model infectious parameters were often shorter than repeated diagnostic data. […] There are limitations of inferring infectiousness from repeated diagnosis, viral loads and viral replication data alone and also potential patient recall bias relevant to estimating exposure and symptom onset times. | 2020-08-08 |
| 32760619 | Clinicians should consider COVID-19 in the differential diagnosis for patients presenting with similar symptoms, especially in areas of a high prevalence of this disease. […] Early diagnosis of COVID-19 in such cases is important for proper isolation, to minimize exposure and avoid further unnecessary investigations. | 2020-08-08 |
| 32760632 | Countries should invest in identifying the hot spots for the origin of zoonotic diseases, enhance diagnostic capabilities, and rapid containment measures at local, regional, and national levels. | 2020-08-08 |
| 32760637 | Some of the questions that have been asked can be addressed by computational modeling based on the use of high-performance computing (HPC) and machine learning techniques. […] The Reference Model previously used such techniques to model diabetes. | 2020-08-08 |
| 32760732 | The global pandemic of coronavirus disease 2019 (COVID-19) has resulted in an increased demand for testing, diagnosis, and treatment. […] Reverse transcription polymerase chain reaction (RT-PCR) is the definitive test for the diagnosis of COVID-19; however, chest X-ray radiography (CXR) is a fast, effective, and affordable test that identifies the possible COVID-19-related pneumonia. | 2020-08-08 |
| 32760733 | This case emphasized the importance of SARS-CoV-2 serology for the diagnosis of delayed immune complications of COVID-19. | 2020-08-08 |
| 32760887 | This clinical practice guideline includes pulmonary rehabilitation (PR) recommendations for adult COVID-19 patients and has been developed in the light of the guidelines on the diagnosis and treatment of COVID-19 provided by the World Health Organization and Republic of Turkey, Ministry of Health, recently published scientific literature, and PR recommendations for COVID-19 regarding basic principles of PR. | 2020-08-08 |
| 32761092 | A diagnostic comparison study was performed to evaluate the performance of the Cepheid Xpert Xpress SARS-CoV-2 assay compared to the Hologic Panther Fusion SARS-CoV-2 assay using clinical nasopharyngeal specimens. | 2020-08-08 |
| 32761102 | The physicians identified 8 oncology-specific, COVID-19-related scenarios in which communication might be challenging: (1) worse outcomes from COVID-19, (2) delay in cancer screening, (3) delay in diagnostic workup, (4) delay in initiation of treatment, (5) offer of nonstandard treatment, (6) treatment breaks, (7) delay in follow-up imaging or care, and (8) inability to be admitted into the hospital for management. | 2020-08-08 |
| 32761228 | We analysed viral load at the time of diagnosis in 53 children and 352 adults with COVID-19 in the first 5 days post symptom onset. | 2020-08-08 |
| 32761260 | The emergence of the novel SARS-CoV-2 pathogen and lethal COVID-19 disease pandemic poses major diagnostic challenges. | 2020-08-08 |
| 32761270 | In situ hybridization (ISH) and immunohistochemistry (IHC) are essential tools to characterize SARS-CoV-2 infection and tropism in naturally and experimentally infected animals and also for diagnostic purposes. | 2020-08-08 |
| 32761481 | Therefore, strengthening the diagnosis of the disease is particularly important for children, and early and clear diagnosis can determine treatment strategies and reduce the harm caused by the disease to children. […] According to the Novel Coronavirus Infection Pneumonia Diagnosis and Treatment Standards (trial version 7) issued by National Health Committee and the latest diagnosis and treatment strategies for novel coronavirus infection pneumonia in children, this review summarizes current strategies on diagnosis and treatment of SARS-CoV-2 infection in children. | 2020-08-08 |
| 32761492 | Upon diagnosis with COVID-19 of critical severity, the patients were admitted to the intensive care unit, where they received early noninvasive-invasive sequential ventilation, early prone positioning, and bundle pharmacotherapy regimen, which consists of antiviral, anti-inflammation, immune-enhancing, and complication-prophylaxis medicines. | 2020-08-08 |
| 32762171 | The candidate epitopes with high reliability can provide reference for virus diagnosis and vaccine development. | 2020-08-08 |
| 32762214 | The advantages and limitations of several methods was compared, which can provide a basis for the selection of 2019 novel coronavirus clinical diagnosis methods. | 2020-08-08 |
| 32762561 | In consideration of the higher risk of mortality in patients with diabetes and COVID-19, novel diagnostic test and treatment strategy are urgently warranted in post-COVID-19 era. | 2020-08-09 |
| 32762696 | A retrospective study was conducted on children with a definite diagnosis of COVID-19 in mainland China using the web crawler technique to collect anonymous COVID-19 updates published by local health authorities. | 2020-08-09 |
| 32762723 | We describe the clinical presentation, diagnosis, treatment, and outcome. | 2020-08-09 |
| 32762737 | Multicentre prospective study that recruited 106 COVID-19 subjects at diagnosis. […] Unfortunately, olfactory and gustatory dysfunction do not seem to hold prognostic value at the time of initial diagnosis. | 2020-08-09 |
| 32762798 | Emergence of SARS-CoV-2 in dengue virus (DENV)-endemic areas complicates the diagnosis of both infections. | 2020-08-09 |
| 32762834 | Only limited evidence has been available to date on the accuracy of systematic low-dose chest computed tomography (LDCT) use in the diagnosis of COVID-19 in patients with non-specific clinical symptoms. […] A diagnosis of COVID-19 was made in 75/191 patients (39%). […] In patients with symptoms compatible with COVID-19, LDCT can esablish the diagnosis of COVID-19 with comparable sensitivity to RT-PCR testing. […] We propose the systematic use of LDCT in addition to RT-PCR testing because it helps correct false-negative RT-PCR results, because its results are available much faster than those of RT-PCRtesting, and because it provides additional diagnostic information useful for treatment planning regardless of the type of the infectious agent. | 2020-08-09 |
| 32762885 | Integrated heart and lung multimodality imaging plays a central role in different clinical settings and is essential in the diagnosis, risk stratification, and management of patients with COVID-19. | 2020-08-09 |
| 32762922 | To create a registry of patients with COVID-19 hospitalized in Spain, in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. | 2020-08-09 |
| 32763024 | We describe the diagnosis, clinical course and management of the patient and their family with regards to clinical, social and infection control measures around delivery. | 2020-08-09 |
| 32763444 | Based on these clinical and neurophysiological findings, a diagnosis of critical illness myopathy was made according to the current diagnostic criteria. | 2020-08-09 |
| 32763810 | The unsatisfactory accuracy and capacity of real time RT-PCR depends on several unavoidable reasons, which cannot meet the demands for COVID-19 diagnosis. 206 serum samples were collected from patients who were treated in the General Hospital of the Central Theater Command of the PLA between January 18 and April 4, 2020. 270 serum samples from healthy blood donors were used as control. […] The CMIA can provide important complementation to nucleic acid assay and help to enhance the accuracy and capacity of diagnosis of SARS-CoV-2 infection. | 2020-08-09 |
| 32763826 | With the global pandemic, the lack of efficient rapid and accurate molecular diagnostic testing tools has hindered the public opportunely response to the emerging viral threat. | 2020-08-09 |
| 32763892 | We aim to apply deep learning techniques as a lower data dependency alternative to estimate transmission parameters of a customized compartmental model, for the purpose of simulating the dynamics of the US coronavirus disease (COVID-19) epidemic and projecting its further development. […] As an alternative, deep learning techniques are effective in estimating these stochastic parameters with greatly reduced dependency on data particularity. | 2020-08-09 |
| 32764120 | Successful management of acute bacterial infections requires early diagnosis and treatment, which are not always easy to achieve. […] Structural imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI) are often applied to this problem. […] The use of nuclear medicine (NM) techniques can add crucial complementary information, allowing visualization of infectious pathophysiology beyond morphologic imaging. […] This review will discuss the current structural and functional imaging techniques used for the diagnosis of bacterial infection and their roles in different clinical scenarios. | 2020-08-09 |
| 32764134 | We collected patients’ medical records: age, comorbidities, COVID-19 history and diagnosis, ventilation supply and ventilator settings, and blood gas results. | 2020-08-09 |
| 32764417 | Based on the current published evidence, herein we summarize the origin, genetics, epidemiology, clinical manifestations, preventions, diagnosis and up to date treatments of SARS-CoV-2 infections in comparison with those caused by SARS-CoV and MERS-CoV. | 2020-08-09 |
| 32765012 | Medical history, imaging data (CT chest findings), and measured hematological and biochemical parameters at diagnosis were recorded in the form of complete blood counts and differential counts; CRP, ESR, serum ferritin, creatinine, and liver function tests . […] Results of real-time reverse transcription-polymerase chain reaction (rRT-PCR) for detection of SARS-CoV-2 RNA at diagnosis and during follow up of these patients were also recorded. | 2020-08-09 |
| 32766088 | We performed a review of the literature and diagnosis data analysis with the aim to reduce the risk of operating a patient infected with SARS-CoV-2/COVID-19 during the incubation period. […] A detailed analysis of the clinical picture and existing diagnostic tests for COVID-19 was performed to achieve the desired objectives. | 2020-08-09 |
| 32766396 | The mean interval time period between the diagnosis of COVID-19 infection and surgery was 2.3±1.5 days. | 2020-08-09 |
| 32766427 | To investigate this, we studied severe acute respiratory syndrome coronavirus 2 diagnostic test results among patients with end-stage renal disease or kidney transplants from the Johns Hopkins Health System (n = 235), and screening test results from deceased donors from the Southwest Transplant Alliance Organ Procurement Organization (n = 27), and donors, candidates, and HCWs from the National Kidney Registry and Viracor-Eurofins (n = 253) between February 23 and April 15, 2020. […] We found low rates of COVID-19 among donors and HCWs (0%-1%) who were screened, higher rates of diagnostic tests among patients with end-stage renal disease or kidney transplant (17%-20%), and considerable mortality (7%-13%) among those who tested positive. | 2020-08-09 |
| 32766497 | Emergency department point of care ultrasound (POCUS) is a first-line modality for diagnosis of CAP. […] An increased use of lung POCUS creates an opportunity for earlier diagnosis while allowing the opportunity for overdiagnosis of small infiltrates and atelectasis. […] We anticipate that early and more frequent use of POCUS and earlier diagnosis of CAP may improve outcomes by decreasing healthcare encounters within the same illness and by reducing the incidence of late sequelae of pneumonia such as empyema and effusions. | 2020-08-09 |
| 32766538 | From 29/02 to 10/03 611 patients with a suspected diagnosis of COVID-19 infection were evaluated in our ED; 320 (52%) met the criteria for hospital admission and 99 (31%) needed to be immediately started on ventilatory support (81% CPAP, 7% NIPPV, 12% Invasive Mechanical Ventilation). | 2020-08-09 |
| 32766567 | Analyze the diagnostic test characteristics of point-of-care lung ultrasound for patients suspected to have novel coronavirus disease 2019. […] The strongest combination of clinical, chest radiograph, and lung ultrasound factors for diagnosis was nondependent bilateral pulmonary edema pattern with temperature and oxygen saturation (area under the curve, 0.86; 95% CI, 0.76-0.94; sensitivity = 77% [58-93%]; specificity = 76% [53-94%] at the ideal cutoff), which was superior to chest radiograph alone. | 2020-08-09 |
| 32766756 | The cohort included patients aged 18 years or older who had a principal discharge diagnosis of AMI (ST-segment elevation myocardial infarction [STEMI] or non-ST-segment elevation myocardial infarction [NSTEMI]). | 2020-08-09 |
| 32766815 | Among those hospitalized (376 [78%]), 117 (31%) required mechanical ventilation, and 77 (20.5%) died by 28 days after diagnosis. | 2020-08-09 |
| 32766824 | There are no distinctive clinical characteristics that will allow the infectious disease consultant to make the diagnosis without laboratory testing. | 2020-08-09 |
| 32767088 | Twelve percent of patients were discharged at diagnosis having potentially unstable fractures. | 2020-08-09 |
| 32767095 | Understanding newly discovered regulatory mechanisms may lead to the development of novel diagnostic and therapeutic targets. | 2020-08-09 |
| 32767263 | These days, in China, chest CT is used for diagnosis of COVID-19, as an important complement to the reverse-transcription polymerase chain reaction (RT-PCR) test. | 2020-08-09 |
| 32767275 | TaqMan-based real-time RT-qPCR is currently the gold standard for COVID-19 diagnosis. […] Both of the proposed assays are less sensitive than the current gold standard; however, our data shows a low sensibility variation, suggesting that these methods could be used by laboratories as a lower cost molecular method for SARS-CoV-2 diagnosis. | 2020-08-09 |
| 32767351 | According to the Guidelines on Novel Coronavirus-Infected Pneumonia Diagnosis and Treatment (Provisional 6th Edition), COVID-19 patients were divided into mild type (7), common type (34), severe type (7) and critical type (10 patients). […] The area under the ROC curve (AUC) of the volume percentage of pneumonia lesions for the whole lung for the diagnosis of severe/critical type COVID-19 was 0.740, with sensitivity and specificity of 91.2% and 58.8%, respectively. […] The clinical and CT imaging features of COVID-19 patients were characteristic to a certain degree; thus, the clinical course and severity of COVID-19 could be evaluated with a combination of an analysis of clinical features and CT imaging features and assistant diagnosis by AI software. | 2020-08-09 |
| 32767631 | This is a case report of a 60-year-old male, without any cardiovascular risk factor and no cardiac history admitted to hospital with a diagnosis of interstitial pneumonia caused by coronavirus disease 2019 (COVID-19). […] Electrocardiogram and transthoracic echocardiogram (TTE) were consistent with a diagnosis of infero-posterolateral acute myocardial infarction and the patient was transferred to the isolated Cath Lab for primary percutaneous coronary intervention (PCI). […] Despite the optimal pharmacological therapies and different PCI techniques, the final TIMI flow was 0/1 and after 3 hr the clinical condition evolved in cardiac arrest for pulseless electric activity. | 2020-08-09 |
| 32767745 | Despite some minor changes in the morphology of the cells, the results of this study highlight that the adoption of the new protocol for the biosafety of LBC-processed samples in pathology laboratories is important for minimizing the risk for personnel, trainees, and cytopathologists without impairing the diagnostic efficacy of the technique. | 2020-08-09 |
| 32767854 | These results are similar to our own experience of 234 patients admitted with COVID-19 according to World Health Organization (WHO) diagnostic guidelines. | 2020-08-09 |
| 32768012 | An echocardiographic investigation is one of the key modalities of diagnosis in cardiology. | 2020-08-10 |
| 32768261 | The topics included in this study are classified in 7 sections: expiration, extended use and reuse of masks, handling techniques, sealing, physical-psychological effects and compliance, contamination and decontamination of respirators. | 2020-08-10 |
| 32768938 | A total of 40 patients with yidu-toxicity blocking lung syndrome, diagnosed as severe pneumonia of SARS-COV-2 following the latest Chinese national recommendations for the diagnosis and treatment of pneumonia caused by SARS-COV-2 (the 5th edition), were recruited. | 2020-08-10 |
| 32768943 | This review will discuss multiple detection methods for coronavirus for developing appropriate, reliable, and fast alternative techniques. […] Considering the current scenario of COVID-19 diagnostics around the world and an urgent need for the development of reliable and cheap diagnostic, various techniques based on CRISPR technology, antibody, MIP, LAMP, microarray, etc. should be discussed and tried. | 2020-08-10 |
| 32768974 | This review summarizes the epidemiology, virology, clinical presentation, pathophysiology, diagnosis, and particularly the antiviral drugs currently under clinical trials for treatment of SARS-CoV-2 infection, together with the challenges and perspectives of this disease are also discussed. | 2020-08-10 |
| 32768975 | Qingfei Paidu decoction (QPD)3 is strongly recommended in the Chinese Novel Coronavirus Pneumonia Diagnosis and Treatment Plan (Provisional 6th Edition). | 2020-08-10 |
| 32769023 | We did not observe any significant cross-reactions for these techniques with the four other seasonal coronaviruses. | 2020-08-10 |
| 32769025 | RT-PCR testing is crucial in the diagnostic of SARS-CoV-2 infection. | 2020-08-10 |
| 32769150 | All patients attended at the rheumatology outpatient clinic of a tertiary hospital in Madrid, Spain with a medical diagnosis of AIRD and with symptomatic COVID-19 were included. | 2020-08-10 |
| 32769214 | Although nasopharyngeal/oropharyngeal swabs are the most commonly used biological samples for SARS-CoV-2 diagnosis, they have a number of limitations related to sample collection and healthcare personnel safety. […] In this context, saliva is emerging as a promising alternative to nasopharyngeal/oropharyngeal swabs for COVID-19 diagnosis and monitoring. […] This review summarises the clinical and scientific basis for the potential use of saliva for COVID-19 diagnosis and disease monitoring. | 2020-08-10 |
| 32769235 | Bronchoscopy plays an important role in diagnosis and therapy of pulmonary diseases, especially in patients with severe pulmonary infection, however, application of bronchoscopy in patients suspected or confirmed SARS-CoV-2 infection is extremely limited for the potential airborne transmission from aerosol generated during the procedure. | 2020-08-10 |
| 32769321 | Diagnostic laboratories testing different types of samples play a vital role in the treatment management. | 2020-08-10 |
| 32769322 | Knowledge of the viral structure, factors that help in its progression and spread, pathological findings, diagnostic methods and, treatment modalities helps in understanding the viral disease and also in treating the patients in a better way besides preventing the community spread of this deadly infection. […] Serological diagnosis helps in diagnosing an ongoing outbreak or retrospective infection. […] This review article thus highlights the global epidemiological status, characteristic of the virus, symptomatology of the patients, role of diagnostic tests available, organs affected including their morphological changes and the latest line of treatment of COVID-19. | 2020-08-10 |
| 32769892 | This study aimed to evaluate the onset characteristics of patients with uremia undergoing maintenance hemodialysis complicated with COVID-19, so as to improve the understanding, diagnosis, and treatment.26 cases were confirmed cases of COVID-19. […] According to the onset characteristics of this population, early diagnosis and treatment could help reduce the risk of developing a critical illness and control the spread of the COVID-19 epidemic. | 2020-08-10 |
| 32769902 | Clinical and biological criteria led to the diagnosis of MAS; cytokine profile was highly suggestive reverse transcription polymerase chain reaction for SARS-CoV-2 in nasopharyngeal swabs was negative, but serum anti-SARS-CoV-2 immunoglobulin A and immunoglobulin G resulted positive leading to the diagnosis of SARS-CoV-2 infection. | 2020-08-10 |
| 32770277 | As we continue to provide care without clear guiding data, we present a discussion of modified anesthetic techniques for pediatric patients with suspected or confirmed COVID-19. | 2020-08-10 |
| 32770341 | Innovative techniques to decrease risk to healthcare providers during AGPs are necessary. | 2020-08-10 |
| 32770367 | Computed tomography (CT) has been utilized as a diagnostic modality in the coronavirus disease 19 (COVID-19), while some studies have also suggested a prognostic role for it. […] This study aimed to assess the diagnostic and prognostic value of computed tomography (CT) imaging in COVID-19 patients. | 2020-08-10 |
| 32770379 | 38.7% stated that their institutions returned to providing diagnostic arthroscopies. | 2020-08-10 |
| 32770582 | This review deals with different microscopy techniques including electron microscopy, atomic force microscopy, fluorescence microscopy as well as computational methods to elucidate various prospects of this life-threatening virus. | 2020-08-10 |
| 32770652 | The main threats to ENT/laryngology SLT clinical services include increased patient complexity related to COVID-19 voice and airway problems, delayed HNC diagnosis, reduced access to instrumental procedures and inequitable care provision. | 2020-08-10 |
| 32770653 | Reverse transcription-polymerase chain reaction is the gold standard diagnostic test to confirm SARS-CoV-2 infection, and although sensitivity can be improved with repeated testing, the decision to retest should incorporate clinical history and the local supply of diagnostic resources. | 2020-08-10 |
| 32770738 | Some clinical, laboratory and radiological findings may help in the differential diagnosis of non-SARS-CoV-2 viruses from COVID-19. | 2020-08-10 |
| 32770807 | Although KD was described by Dr Kawasaki over 50 years ago, there is still no specific diagnostic test and the aetiology remains elusive. | 2020-08-10 |
| 32771058 | As the outbreak of coronavirus disease 2019 (COVID-19) has progressed, computed tomography has emerged as an integral part of the diagnosis alongside reverse transcriptase-polymerase chain reaction assays. […] It has emerged as an integral part of the diagnosis of COVID-19 alongside reverse transcriptase-polymerase chain reaction assays. | 2020-08-11 |
| 32771068 | Individuals also cannot participate if they have a self-reported history of head injuries, or if they have a self-reported diagnosis of schizophrenia, epilepsy or personality disorder, as the distraction techniques involved in the insomnia intervention may increase rumination in individuals with these conditions, and influence the effectiveness of the intervention. […] Briefly, this self-help leaflet aims to improve sleep by identifying and addressing sleep-related dysfunctional thinking by providing education about sleep, providing techniques to distract from intrusive worrisome thoughts at night, and providing guidelines for sleep-related stimulus control. | 2020-08-11 |
| 32771222 | There was no missed diagnosis of COVID-19 with LUS compared with CT in our cohort. | 2020-08-11 |
| 32771337 | Front-line professionals exposed and involved in the diagnosis and treatment of COVID-19 patients are more susceptible. | 2020-08-11 |
| 32771560 | Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities. | 2020-08-11 |
| 32771632 | In this national cohort of over 10,000 patients with COVID-19, more than 60% of all cases in South Korea reported no symptoms at the time of diagnosis. | 2020-08-11 |
| 32771634 | We define the diagnostic serial interval as the time between the diagnosis dates of the infector and infectee. […] Based on the DS4C project data on SARS-CoV-2/COVID-19 in South Korea, we estimate the means of the diagnostic serial interval, the clinical onset serial interval, and the difference between the two. […] The mean of the diagnostic serial interval was estimated to be 3.63 days (95% CI: 3.24, 4.01). […] The diagnostic serial interval was significantly shorter than the clinical onset serial interval (estimated mean difference -1.12 days, 95% CI: -1.98, -0.26). […] The relatively short diagnostic serial intervals of SARS-CoV-2/COVID-19 in South Korea are likely due to the country’s extensive efforts towards contact tracing. […] We propose the mean diagnostic serial interval as a new indicator for the effectiveness of a country’s contact tracing as part of the epidemic surveillance. | 2020-08-11 |
| 32771640 | We examined routine Full Blood Count (FBC) specimens that were surplus to routine diagnostic requirements; normal ranges were established in a historic group of healthy volunteers. | 2020-08-11 |
| 32771920 | Regression model such as Linear and Multiple Linear Regression techniques are applied to the data set to visualize the trend of the affected cases. | 2020-08-11 |
| 32771946 | Rapid diagnosis remains a bottleneck for containing the epidemic. | 2020-08-11 |
| 32771976 | Implementing fast and widespread diagnostic tests is paramount to contain COVID-19, given the current lack of an effective therapeutic or vaccine. […] This review focuses on a broad description of currently available diagnostic tests to detect either the virus (SARS-CoV-2) or virus-induced immune responses. | 2020-08-11 |
| 32772053 | We cannot rule out that a new diagnostic category for specific mental disorders resulting from the COVID-19 pandemic may emerge in the near future. […] This paper presents the extent of the impact of the pandemic on the development of mental instability and current diagnostic possibilities. | 2020-08-11 |
| 32772172 | MRI of the cervical spine demonstrated longitudinally extensive transverse myelitis, and EMG was consistent with the diagnosis of AMAN. | 2020-08-11 |
| 32772892 | To address this, immuno-informatics techniques have been employed to design multi-epitope vaccine construct. | 2020-08-11 |
| 32773099 | In the first months, there have been uncertainties on almost any area: infection transmission route, virus origin and persistence in the environment, diagnostic tests, therapeutic approach, high-risk subjects, lethality, and containment policies. | 2020-08-11 |
| 32773251 | The COVID-19 pandemic has forced the establishment of preventive measures against contagion during the performance of diagnostic and therapeutic tests in gastroenterology. | 2020-08-11 |
| 32773400 | Due to the scarcity of the COVID-19 benchmark dataset, we have employed deep transfer learning techniques, where we examined 15 different pre-trained CNN models to find the most suitable one for this task. […] This study demonstrates the effectiveness of deep transfer learning techniques for the identification of COVID-19 cases using CXR images. | 2020-08-11 |
| 32773409 | This review provides an update on clinical features, diagnosis, epidemiology, management and prevention of coronavirus disease 2019 (COVID-19) in children. | 2020-08-11 |
| 32773471 | We assessed clinical characteristics, risk factors for COVID-19 diagnosis and severity, and standardized incidence rate ratio for COVID-19 cases in PLWH cohort and in Barcelona. […] No HIV or antiretroviral-related factors were associated with COVID-19 diagnosis or severity. | 2020-08-11 |
| 32773511 | Clinical-demographic data of the patients, indications, type of endoscopy, endoscopic findings (subtyped in major and minor), finding rates (major and minor) and diagnostic yields (major findings) have been analyzed and compared to the endoscopic procedures performed in March 2019. […] The finding rates and diagnostic yields were 83% (74-89) vs 71% (66-73) (P 0.015) and 56% (46-65) vs 43% (38-47) (P 0.03) on March 2020 and March 2019, respectively. […] The novel endoscopic triage significantly reduced the number of procedures and increased finding rates and diagnostic yields. | 2020-08-11 |
| 32773584 | As of April 15, 2020, the US Food and Drug Administration has granted emergency use authorization to a first saliva test for diagnosis of severe acute respiratory syndrome coronavirus 2 infection, the device developed by RUCDR Infinite Biologics laboratory, Rutgers University. […] Therefore, in this mini-review article, we aimed to summarize the current and emerging tools, focusing on diagnostic power of different clinical sampling and specimens. | 2020-08-11 |
| 32773657 | Secretions collected with a nasopharyngeal swab underwent diagnostic testing using multiplex polymerase chain reaction. […] The most frequent syndromic diagnosis was common cold (41%), followed by bronchiolitis (27%). […] We found no association between the infecting HCoV type and subject’s syndromic diagnosis (P > 0.05) or anatomic location of infection (upper vs. lower respiratory tract; P > 0.05). | 2020-08-11 |
| 32773929 | The questionnaire was pretested and developed using standard techniques. | 2020-08-11 |
| 32774007 | Radiology department remains the backbone for diagnosis and for appropriate management of orthopaedic ailments. […] Amidst COVID-19 pandemic, there is a need to change in imaging algorithm, for various clinical conditions taking care of the exposure risk to patients and healthcare workers and to handle the volume of diagnostic and intervention work. | 2020-08-11 |
| 32774008 | A diagnosis of COVID 19 was made on the basis of positive Computed Tomography scan in 39 patients and 30 patients had a positive Reverse Transcription-Polymerase Chain Reaction test. | 2020-08-11 |
| 32774121 | Their actual diagnostic specificity, sensitivity and predictive value need to be tested on a larger number of subjects. | 2020-08-11 |
| 32774178 | To quickly diagnose and control such a highly infectious disease, suspicious individuals were isolated and diagnostic/treatment procedures were developed through patients’ epidemiological and clinical data. […] Early in the COVID-19 outbreak, WHO invited hundreds of researchers from around the world to develop a rapid quality diagnosis, treatment and vaccines, but so far no specific antiviral treatment or vaccine has been approved by the FDA. | 2020-08-11 |
| 32774639 | Early diagnosis and management is key to favourable outcomes. […] More rapid and faster diagnostic tests that may produce results within minutes to a few hours will be instrumental in controlling the disease. […] In this review, we extensively searched for studies that compared RT-PCR with serological tests for the diagnosis of COVID-19. […] Finally, we discuss the relevance of the different diagnostic tests and the importance of genome sequencing in identifying potential therapeutic options for the control of COVID-19 in Africa. | 2020-08-11 |
| 32775188 | The diagnosis of Coronavirus Disease 2019 (COVID-19) is based on the identification of common symptoms such as fever, tiredness and dry cough. | 2020-08-11 |
| 32775372 | This means that these patients require multidisciplinary treatment including early diagnosis, timely transport, emergency surgery and intensive critical care. | 2020-08-11 |
| 32775378 | Medical techniques were implemented to improve the recovery rate and control the epidemic. […] Optimizing the diagnosis process, shortening the diagnosis time, and constructing teams of clinical experts facilitated the provision of “one team of medical experts for each patient” treatment for severe patients, which significantly improved the recovery rate and reduced the infection fatality rate. | 2020-08-11 |
| 32775778 | Cox regression models were used to identify predictors of death after COVID-19 diagnosis. […] A logistic model was used to characterize the association between mean lung radiation therapy dose and 14-day mortality risk after COVID-19 diagnosis. […] With a median follow-up of 7 days from COVID-19 diagnosis for surviving patients, 24 deaths have been observed. […] Increasing mean lung dose (hazard ratio [HR] per Gy = 1.1, P = .002), lung cancer diagnosis (HR = 3.0, P = .034), and receiving radiation therapy between 1 month and 1 year before COVID-19 testing (HR = 3.4, P = .013) were associated with increased risk of death. […] Our survival model demonstrates a near linear relationship between mortality risk after COVID-19 diagnosis and mean lung radiation therapy dose. | 2020-08-11 |
| 32775781 | Lung windows of daily CBCT scans were reviewed with diagnostic radiology to survey for changes consistent with COVID-19. […] Diagnostic CT scans at the time of recovery were obtained and compared with the CBCTs. […] Diagnostic CTs demonstrated bilateral, peripheral GGOs and mediastinal lymphadenopathy, findings suggesting COVID-19 pneumonitis. […] Repeat diagnostic CT 3 days later showed improved pulmonary findings, and the patient resumed RT without incident. […] Prompt review of the lung windows is recommended to identify such changes, with the hope that presymptomatic diagnosis leads to expedited patient management, improved outcomes, and a reduction of inadvertent COVID-19 dissemination. | 2020-08-11 |
| 32776139 | Osteopathic manipulative treatment techniques to mitigate the underlying pathology were identified, and modifications for use in pregnancy and the critical care setting are described. | 2020-08-11 |
| 32776243 | It is unclear whether a delay between diagnosis and surgical management (i.e., surgical delay) may have a detrimental effect on oncologic outcomes of PCa patients. | 2020-08-11 |
| 32776551 | The impact of age and sex on WMDs was estimated using meta-regression techniques for 11 markers. | 2020-08-11 |
| 32776725 | Saliva sample itself is not appropriate for initial diagnosis of coronavirus disease 2019 (COVID-19) to replace NP/OP swabs, especially for the person who does not produce sputum. | 2020-08-11 |
| 32776832 | BackgroundThe use of chest CT for COVID-19 diagnosis or triage in healthcare settings with limited SARS-CoV-2 PCR capacity is controversial. […] CO-RADS categorization of the level of COVID-19 suspicion might improve diagnostic performance.PurposeTo investigate the value of chest CT with CO-RADS classification to screen for asymptomatic SARS-CoV-2 infections and to determine its diagnostic performance in individuals with COVID-19 symptoms during the exponential phase of viral spread.Materials and MethodsIn this secondary analysis of a prospective trial (Clinical Trial Number: IRB B1172020000008), from March 2020 to April 2020, we performed parallel SARS-CoV-2 PCR and CT with categorization of COVID-19 suspicion by CO-RADS, for individuals with COVID-19 symptoms and controls without COVID-19 symptoms admitted to the hospital for medical urgencies unrelated to COVID-19. […] AUC were calculated in symptomatic versus asymptomatic individuals to predict positive SARS-CoV-2 positive PCR and likelihood ratios for each CO-RADS score were used for rational selection of diagnostic thresholds.Results859 individuals (median 70 years, IQR 52-81, 443 men) with COVID-19 symptoms and 1138 controls (median 68 years, IQR 52-81, 588 men) were evaluated. […] CT-CORADS had good diagnostic performance (P<.001 in both symptomatic and asymptomatic individuals. conclusionct-corads had good diagnostic performance individuals supporting its application for triage.> | 2020-08-11 | </.001>
| 32776905 | The prevalence of anosmia would be influenced by self-diagnosis as well as self-misdiagnosis in patients with COVID-19. | 2020-08-11 |
| 32777301 | Hence, this systematic review aims to evaluate the effectiveness of the molecular detection techniques in COVID-19. | 2020-08-11 |
| 32777318 | Although new skin manifestations caused by COVID-19 are continuously being described, other cutaneous entities should also be considered in the differential diagnosis, including adverse cutaneous reactions to drugs used in the treatment of COVID-19 infections. […] Information regarding possible skin reactions, their frequency, management, and key points for differential diagnosis are presented. | 2020-08-11 |
| 32777322 | Previously developed models were adapted for 110 countries to include a status quo or “no delay” scenario and a “1-year delay” scenario assuming significant disruption in interventions (screening, diagnosis and treatment) in the year 2020. | 2020-08-11 |
| 32777401 | The profound effects on spine surgery call for systematic approaches to optimizing the diagnosis and treatment of spinal diseases. | 2020-08-11 |
| 32777550 | The aim of our systematic review was to investigate symptoms and diagnostic-therapeutic management of IBD patients with COVID-19. […] The most common symptoms were fever (48.3%), cough (46.5%), and diarrhea (20.5%), and a COVID-19 diagnosis was achieved mainly through polymerase chain reaction analysis of nasopharyngeal swabs (94.4%) and chest computed tomography scans (38.9%). […] Further studies are needed to define the optimal diagnostic-therapeutic approach in IBD patients with COVID-19. | 2020-08-11 |
| 32777726 | The rapid and accurate monitoring and determination of pathogens are of great significance to clinical diagnosis, food safety and environmental evaluation. | 2020-08-11 |
| 32777761 | The SARS-CoV-2 pandemic has challenged molecular microbiology laboratories to quickly implement and validate diagnostic assays and to expand testing capacity in a short timeframe. […] Multiple molecular diagnostic methods received FDA emergency use authorization (EUA) and were promptly validated for use nationwide. | 2020-08-11 |
| 32777762 | Molecular detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is key in the diagnosis of coronavirus disease 2019 (COVID-19) and has been widely used for followup of cases as a proxy for contagiousness. […] The most common symptoms at diagnosis were cough, myalgia, dyspnea, fever and chills. […] The findings of our study highlight the low yield of repeating a SARS-CoV-2 NP PCR test within 21 days of a laboratoryconfirmed COVID-19 diagnosis. | 2020-08-11 |
| 32777798 | The diagnostic sensitivity of the SARS-CoV-2 real time reverse transcription polymerase chain reaction (RT-PCR) test has not been determined. | 2020-08-11 |
| 32777861 | In total, 200 anaesthetists, midwives and obstetricians, with no previously confirmed diagnosis of COVID-19, were tested for immune seroconversion using laboratory IgG assays. | 2020-08-11 |
| 32777883 | Epidemiological surveys and diagnostic tests were conducted for each contact, and the secondary attack rate was estimated. | 2020-08-12 |
| 32778554 | To evaluate whether the diagnosis of pediatric type 1 diabetes or its acute complications changed during the early phase of the coronavirus disease 2019 (COVID-19) pandemic in Italy. | 2020-08-12 |
| 32778630 | Real-Time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) was absolutely needed to determine the correct diagnosis. | 2020-08-12 |
| 32779165 | Timing for deferrals of diagnostic-therapeutic procedures were mostly covered in the guidelines. | 2020-08-12 |
| 32779188 | Recent recommendations promote diagnostic approaches that limit collection but increase undiagnosed GDM, which potentially increases adverse pregnancy outcome risks. | 2020-08-12 |
| 32779445 | These results can be helpful to design specific diagnostic tests, trace the SARS-CoV-2 sequence changes in Iran, and explore therapeutic drugs and vaccines. | 2020-08-12 |
| 32779744 | Joint detection of nucleic acids and antibodies has become an important laboratory diagnostic for COVID-19 patients. […] These data will provide a theoretical basis for clinical diagnosis and treatment. | 2020-08-12 |
| 32779772 | To provide flexible diagnostic options for such environments, we report here an “unextracted modification” for qRT-PCR using the Centers for Disease Control’s (CDC’s) widely utilized primers/probe sets for severe acute respiratory syndrome coronavirus 2 (N1/N2/N3 targeting viral nucleocapsid and RP-control targeting human RNase P). | 2020-08-12 |
| 32779808 | We performed a prospective cohort study of hospitalized patients with confirmed diagnosis of COVID-19, from March 15 to April 30, 2020, at two tertiary hospitals in Emilia-Romagna Region. […] Patients were assessed from COVID-19 diagnosis to death or 30-day whichever occurred first. | 2020-08-12 |
| 32779823 | The rapidly accumulating knowledge about COVID-19 allows a better understanding of the diagnostic tools that may be potentially used in screening. | 2020-08-12 |
| 32779925 | To describe the diagnosis, symptomatology and disease course of COVID-19 in nursing home (NH) residents in the Netherlands. […] Data were collected on diagnostic status (COVID-19: confirmed/excluded (using the RT-PCR test)), symptomatology (typical/atypical and other symptoms, body temperature and oxygen saturation) and, in the case of confirmed COVID-19, on disease course (recovered/clinically improved/deteriorated, deceased). […] The diagnosis was confirmed in 857 patients (43.5%); diagnosis was excluded in 1,112 (56.5%) patients. | 2020-08-12 |
| 32779955 | Positive exposure to otolaryngology can increase medical students’ interest in pursuing the specialty and expand their general knowledge of consultation, diagnosis, and management in otolaryngology. | 2020-08-12 |
| 32780290 | Beyond the pathogenesis of SARS-CoV-2, microbial coinfection plays an important role in the occurrence and development of SARS-CoV-2 infection by raising the difficulties of diagnosis, treatment, prognosis of COVID-19, and even increasing the disease symptom and mortality. […] We summarize the coinfection of virus, bacteria and fungi with SARS-CoV-2, their effects on COVID-19, the reasons of coinfection, and the diagnosis to emphasize the importance of microbial coinfection in COVID-19. […] • Microbial coinfection exacerbates the processes of the occurrence, development and prognosis of COVID-19, and the difficulties of clinical diagnosis and treatment. | 2020-08-12 |
| 32780493 | Univariate and multivariable techniques were used to compare differences between groups and to control for case-mix. 197 (3·8%) of the 5,184 wait-listed patients and 597 (1·3%) of the 46,789 SOT recipients tested positive for SARS-CoV-2. | 2020-08-12 |
| 32780717 | The pandemic of COVID-19 has presented several diagnostic challenges in both recognition of acute disease and also the temporal presentation of disease convalescence with return to normal activity. | 2020-08-12 |
| 32780793 | The proportions of participants with a negative conversion at day 14 and day 21 from diagnosis were 33.7% and 75.2%, respectively, in asymptomatic patients and 29.6% and 69.9%, respectively, in symptomatic patients (including presymptomatic patients). […] The median (SE) time from diagnosis to the first negative conversion was 17 (1.07) days for asymptomatic patients and 19.5 (0.63) days for symptomatic (including presymptomatic) patients (P = .07). […] The Ct values for the envelope (env) gene from lower respiratory tract specimens showed that viral loads in asymptomatic patients from diagnosis to discharge tended to decrease more slowly in the time interaction trend than those in symptomatic (including presymptomatic) patients (β = -0.065 [SE, 0.023]; P = .005). | 2020-08-12 |
| 32780851 | This will likely lead to delayed diagnosis, a shift to later stage disease, and increased CRC deaths. | 2020-08-12 |
| 32781617 | In this review, we have systematically summarized the epidemiological studies, clinical features, biological properties, diagnostic methods, treatment modalities, and preventive measurements related to COVID-19. | 2020-08-13 |
| 32781623 | The diagnosis of COVID-19 was based on laboratory-confirmed diagnosis of SARS-CoV-2. […] Intracranial bleeding was diagnosed on computed tomography (CT) of the brain within one month of the date of COVID-19 diagnosis. | 2020-08-13 |
| 32782044 | The present consideration statement summarizes current strategies on pre-diagnosis, triage, diagnosis, treatment, and prevention of 2019-nCoV infection, which provide practical suggestions on strengthening the management of pediatric fever clinics during the novel coronavirus pneumonia epidemic period. | 2020-08-13 |
| 32782059 | There is a need for innovative and regular educational activities for all stakeholders committed to safeguarding our future defense systems concerning diagnostic, protection, treatment, and rehabilitation in pandemics, as well as other emergencies. | 2020-08-13 |
| 32782108 | Two months afterward, a questionnaire was prepared regarding the preventive measures practiced by renal transplant recipients, and patients were asked whether they had any COVID-19 symptoms or had received a COVID-19 diagnosis. | 2020-08-13 |
| 32782109 | At the peak of the outbreak in Wuhan (January and February), there are two types of COVID-19 patients: laboratory confirmation and clinical diagnosis. | 2020-08-13 |
| 32782131 | Patients were included if they underwent TTE during the hospitalization after a known positive diagnosis for COVID-19. […] This study describes the clinical indications for use and diagnostic performance of TTE, as well as findings seen on TTE, in hospitalized patients with COVID-19. | 2020-08-13 |
| 32782765 | NMD display varying levels of disability in people with the same diagnosis, thus it is difficult to give COVID-19 related general recommendations. | 2020-08-13 |
| 32782784 | We describe a 55-year-old woman with severe idiopathic pulmonary arterial hypertension (mean pulmonary artery pressure 71 mmHg, pulmonary vascular resistance 30 WU at diagnosis five months ago), who was diagnosed with SARS-CoV-2 infection (COVID-19) and experienced a relatively mild course with symptoms resembling a common cold. | 2020-08-13 |
| 32782878 | Hypovolemic hyponatremia should be distinguished from SIADH as these conditions employ different management strategies, and early diagnosis and management of hypovolemic hyponatremia affects morbidity and mortality. | 2020-08-13 |
| 32783040 | This review has attempted to explain the various aspects of the disease itself, its diagnosis, the use of personal protective equipment (PPE) to provide an overview of the evolving recommendations in head and neck patients, the future outlook and the limitations faced in developing countries specifically for ENT patients. | 2020-08-13 |
| 32783207 | Patient data on indications, diagnosis, types of procedures, and the results of COVID-19 tests were recorded. […] This study included 126 patients; 36 required interventional bronchoscopic techniques (28.6%), 74 required endobronchial ultrasonography (EBUS; 58.7%), and 16 required flexible fiberoptic bronchoscopy (12.7%). […] All interventional rigid bronchoscopic techniques were performed for emergent indications: malignant airway obstruction (66.7%), tracheal stenosis (25%), and bronchopleural fistula (8.3%). | 2020-08-13 |
| 32783494 | This communication describes the epidemiology, diagnostic test results and clinical findings of neonatal COVID-19 during the pandemic in Iran. | 2020-08-14 |
| 32783619 | The identification of other RAS components in COVID-19 hypertension may provide both diagnostic and therapeutic benefits. | 2020-08-14 |
| 32784192 | A total of 176 hospitalized patients with a confirmed COVID-19 diagnosis was included. | 2020-08-14 |
| 32784236 | Since the beginning of the COVID-19 pandemic, healthcare providers worldwide have faced many obstacles in the diagnostic evaluation of patients for severe acute respiratory syndrome coronavirus 2, the causative virus. […] Even with the application of statistical inference by Bayes’ theorem to estimate the probability of a diagnosis, with and without testing capabilities, some cases may still carry a degree of uncertainty. […] The basis for isolation and quarantine is a known diagnosis. […] This case is an example of a diagnostic conundrum that required more thorough use of testing methods, particularly serological testing, to guide the isolation recommendations for a patient with COVID-19. | 2020-08-14 |
| 32784239 | The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has presented many diagnostic challenges and uncertainties. […] Although an initial diagnostic dilemma, a multidisciplinary team approach was required to ensure a favourable outcome for both the mother and the baby. | 2020-08-14 |
| 32784243 | A 63-year-old man was admitted with left-sided weakness and subsequent focal seizures following a recent diagnosis of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in a nearby hospital. | 2020-08-14 |
| 32784244 | A 36-year-old previously healthy woman with no personal or family history of mental illness presented with new-onset psychosis after a diagnosis of symptomatic COVID-19. | 2020-08-14 |
| 32784757 | The standard diagnostic pipeline for testing SARS-CoV-2 presence in patients with an ongoing infection is predominantly based on pharyngeal swabs, from which the viral RNA is extracted using commercial kits, followed by reverse transcription and quantitative PCR detection. […] Importantly, the presented diagnostic workflow can be quickly set up in a laboratory without access to an automated pipetting robot. | 2020-08-14 |
| 32784770 | Sensitive molecular assays are critical for coronavirus disease 2019 (COVID-19) diagnosis. | 2020-08-14 |
| 32784826 |
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2020-08-14 |
| 32785481 | The strengthening of the diagnostic infrastructure reappears as an opportunity for the national reference laboratories. | 2020-08-14 |
| 32785570 | Serologic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) promises to assist in assessing exposure to and confirming the diagnosis of coronavirus disease 2019 (COVID-19), and to provide a roadmap for reopening countries worldwide. […] Considering this, a proper understanding of serologic-based diagnostic testing characteristics is critical. […] The aim of this study was to perform a structured systematic review and meta-analysis to evaluate the diagnostic characteristics of serological-based COVID-19 testing. […] Full-text observational studies that reported IgG or IgM diagnostic yield and used nucleic acid amplification tests (NAATs) of respiratory tract specimens, as a the reference standard in English language were included. […] A bivariate model was used to compute pooled sensitivity, specificity, positive/negative likelihood ratio (LR), diagnostic odds ratio (OR), and summary receiver operating characteristic curve (SROC) with corresponding 95% confidence intervals (CIs). […] The pooled sensitivity, specificity, and diagnostic accuracy for IgG was 81% [(95% CI, 61-92);I2=95.28], 97% [(95% CI, 78-100);I2=97.80], and 93% (95% CI, 91-95), respectively. […] This meta-analysis demonstrates suboptimal sensitivity and specificity of serologic-based diagnostic testing for SARS-CoV-2 and suggests that antibody testing alone, in its current form, is unlikely to be an adequate solution to the difficulties posed by COVID-19 and in guiding future policy decisions regarding social distancing and reopening of the economy worldwide. | 2020-08-14 |
| 32785701 | Previous studies showing a correlation between certain laboratory tests and diagnosis suggest an alternative method based on an ensemble of tests. […] While molecular-based and antibody tests remain the reference standard method for confirming a SARS-CoV-2 diagnosis, their clinical sensitivity is not well known. | 2020-08-14 |
| 32785855 | While a definite diagnosis is based on microbiological evidence, the relationship between lung ultrasound (LU) and high-resolution computed tomography (HRCT) in the diagnosis and management of COVID-19 is less clear. […] Aims of this review are to describe LU and chest HRCT main imaging features of COVID-19 pneumonia, and to provide state-of-the-art insights regarding the integrated role of these techniques in the clinical decision-making process of patients affected by this infectious disease. | 2020-08-14 |
| 32785885 | We report of two cases of progressed COVID-19 with negative PCR tests from nasopharyngeal swabs, in whom diagnosis was made by different antibody assays, including a lateral flow rapid test and multiple commercial ELISAs, finally confirmed by comprehensive serological assays. […] These cases highlight that commercial ELISAs and even rapid tests might significantly aid the diagnosis of COVID-19, particularly, if a combination of serological assays is used with a specific clinical question, in severely ill patients after seroconversion and when comprehensive serological methods are used for confirmation. | 2020-08-14 |
| 32786273 | Since human-to-human transmission occurs easily and the rate of human infection is rapidly increasing, sensitive and early diagnosis is essential to prevent a global outbreak. | 2020-08-14 |
| 32786280 | Clinically, the diagnosis of this unprecedented illness, called coronavirus disease-2019 (COVID-19), becomes difficult because it shares many symptoms with other respiratory pathogens, including influenza and parainfluenza viruses. […] Therefore, laboratory diagnosis is crucial for the clinical management of patients and the implementation of disease control strategies to contain SARS-CoV-2 at clinical and population level. […] Here, we summarize the main clinical and imaging findings of COVID-19 patients and discuss the advances, features, advantages, and limitations of different laboratory methods used for SARS-CoV-2 diagnosis. | 2020-08-14 |
| 32786383 | The global sanitary crisis caused by the emergence of the respiratory virus SARS-CoV-2 and the COVID-19 outbreak has revealed the urgent need for rapid, accurate, and affordable diagnostic tests to broadly and massively monitor the population in order to properly manage and control the spread of the pandemic. […] Current diagnostic techniques essentially rely on polymerase chain reaction (PCR) tests, which provide the required sensitivity and specificity. […] Next-generation diagnostic tools capable of overcoming all the above limitations are in demand, and optical biosensors are an excellent option to surpass such critical issues. […] Taking the current COVID-19 pandemic as a critical case scenario, we provide an overview of the diagnostic techniques for respiratory viruses and analyze how nanophotonic biosensors can contribute to improving such diagnostics. […] We review the ongoing published work using this biosensor technology for intact virus detection, nucleic acid detection or serological tests, and the key factors for bringing nanophotonic POC biosensors to accurate and effective COVID-19 diagnosis on the short term. | 2020-08-14 |
| 32786452 | It was recently reported that the human receptor angiotensin-converting enzyme 2 (ACE2) plays a key role for capturing SARS-CoV-2 into the human target body, and binding studies were performed using biosensors techniques based on surface plasmon resonance and bio-layer interferometry. | 2020-08-14 |
| 32786511 | Outstandingly, DLIGAND2 emerged as the best scoring function on this data set, outperforming all rescoring techniques in terms of VS metrics. | 2020-08-14 |
| 32786682 | The detection of viral RNA by polymerase chain reaction (PCR) is currently the main diagnostic tool for COVID-19 (Eurosurveillance 2019, 25 (3), 1). | 2020-08-14 |
| 32787373 | The diagnostic and classification criteria were based on the 7th edition of Diagnosis and Treatment Guideline of COVID-19 published by the National Health Commission of the People’s Republic of China. | 2020-08-14 |
| 32787398 | The use of SARS-CoV-2 rapid diagnostic test (RDT) kits by some African countries for screening has raised serious concerns over their role in malaria areas. | 2020-08-14 |
| 32787510 | Bold revisions of the diagnostic criteria leading to dramatic changes in death tolls by different governments were observed in attempts to generate more accurate estimates. | 2020-08-14 |
| 32787527 | In conclusion, RNA and antibodies should be combined for COVID-19 diagnosis, and delayed seroconversion was influenced by the decreased lymphocytes and short positive conversion time for RNA. | 2020-08-14 |
| 32787597 | Outcomes measured included study characteristics, cancer type, phase of care at the time of diagnosis, and clinical presentation. | 2020-08-14 |
| 32787707 | Given that severe strokes are typically associated with poor prognosis and can be very efficiently treated with recanalization techniques, confirmation of this putative association is urgently warranted in a large representative patient cohort to alert stroke clinicians, and inform pre- and in-hospital acute stroke patient pathways. | 2020-08-14 |
| 32787956 | This case highlights a previously undocumented COVID-19 presentation and suggests that even mildly symptomatic infants warrant viral diagnostic testing in an effort to prevent further spread of the disease. | 2020-08-14 |
| 32788432 | Further studies and longer surveillance of patients with MIS-C are required to improve our diagnostic, treatment and surveillance criteria. | 2020-08-14 |
| 32788768 | The reverse transcriptase-polymerase chain reaction is the current gold standard diagnostic test and chest Computed Tomography scan for screening the disease is considered inappropriate by most society recommendations. | 2020-08-14 |
| 32788841 | Techniques used within UBPI were adopted from a variety of well established psychotherapies and distilled into its core essentials. | 2020-08-14 |
| 32788913 | Early diagnosis, treatment and future prevention are keys to COVID-19 management. […] Currently, the unmet need to develop cost-effective point-of-contact test kits and efficient laboratory techniques for confirmation of COVID-19 infection has powered a new frontier of diagnostic innovation. […] Based on the currently published evidence, we tried to highlight different diagnostic approaches, side effects and therapeutic agents that could help physicians in the frontlines. | 2020-08-14 |
| 32789084 | There were four patients (30.8%) of tuberculosis of the spine of whom two (50%) were managed with posterior decompression, debridement, and stabilization with pedicle screws, samples for culture, biopsy, and cartridge-based nucleic acid amplification test (CBNAAT) were collected during the procedure; for the remaining two patients (50%), a trans-pedicular biopsy was performed to confirm the diagnosis for initiation of anti-tubercular therapy. | 2020-08-14 |
| 32789106 | The diagnosis of military tuberculosis was made. | 2020-08-14 |
| 32789143 | Clinical experience and scientific articles have shown that patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be paucisymptomatic or asymptomatic at the time of diagnosis. […] In these cases, lung ultrasound helped to raise clinical suspicion of COVID-19 pneumonia and facilitate diagnosis. […] During the current COVID-19 pandemic, lung ultrasound (LUS) is being used extensively to evaluate and monitor lung damage in infected patients.Several patients have been described with negative PCR swabs who tested positive for SARS-CoV-2 in bronchoalveolar lavage fluid.Typical signs of interstitial pneumonia on LUS strongly indicate COVID-19 pneumonia, thus suggesting further investigation and invasive tests to confirm the diagnosis. | 2020-08-14 |
| 32789604 | The diagnosis and management of HIT is particularly challenging in COVID-19 patients receiving ECMO support. | 2020-08-14 |
| 32789807 | The increasing trend of chest CT utilization during the COVID-19 pandemic necessitates novel protocols with reduced dose and maintained diagnostic accuracy. […] We aimed to investigate the diagnostic accuracy of 30-mAs chest CT protocol in comparison with a 150-mAs standard-dose routine protocol for imaging of COVID-19 pneumonia. […] Diagnostic accuracy of low-dose and standard-dose CT in the detection of typical COVID-19 pneumonia features were compared. | 2020-08-14 |
| 32790181 | During coronavirus disease 2019 (COVID-19) pandemic, the early diagnosis of patients is a priority. […] The inclusion of the IgA antibodies determination among serological tests of the COVID-19 diagnostic is recommended. | 2020-08-14 |
| 32790215 | Diagnosis of secondary headache disorders is still based on the presence of red flags. | 2020-08-14 |
| 32790779 | Here, we demonstrate the use of the miniPCR, a commercial compact and portable PCR device recently available on the market, in combination with a commercial well-plate reader as a diagnostic system for detecting genetic material of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal agent of COVID-19. | 2020-08-14 |
| 32790804 | A diagnosis at risk of COVID-19 was registered in 6692 (43%) consultations,. | 2020-08-14 |
| 32790891 | COVID-19 diagnosis is a critical problem, mainly due to the lack or delay in the test results. […] With a data subset including 80% of patients from Sao Paulo (SP) and Rio Janeiro (RJ), we obtained a function which reached an AUC of 95.54% (95% CI: 94.41-96.67%) for the diagnosis of COVID-19 and accuracy of 90.1% (sensitivity 87.62% and specificity 92.02%). […] We obtained a model suitable for the clinical diagnosis of COVID-19 based on routinely collected surveillance data. | 2020-08-14 |
| 32790918 | None of the patients met HLH-2004 diagnostic criteria. | 2020-08-14 |
| 32791382 | To resume some suspended social activities, early diagnosis and contact tracing are essential. […] To meet this required diagnostic and screening capacity, high throughput diagnostic assays are needed. […] The NeuMoDx™ SARS-CoV-2 assay, performed on a NeuMoDx molecular system, is a rapid, fully automated, qualitative real-time RT-PCR diagnostic test with throughput of up to 288 tests in an 8 -h shift. | 2020-08-14 |
| 32791731 | According to the diagnostic criteria for COVID-19 pneumonia in the “New Coronavirus Prevention and Control Plan Fifth Edition” of the National Health Commission of China, she was diagnosed as a clinically confirmed case. | 2020-08-15 |
| 32792044 | This paper discusses the methodology of estimating the detection and diagnostic accuracy of COVID-19 tests. […] It explains the clear distinction between the technical characteristics of the tests, the detection measures, and the diagnostic measures that have clinical and public health implications. […] It demonstrates the importance of the prevalence of COVID-19 in terms of determining the ability of a test to yield a diagnosis. […] We explain the methodology of evaluating diagnostic tests, using the predictive summary index (PSI), and the minimum number of tests that need to be performed in order to correctly diagnose one person, which is estimated by 1/PSI. […] In a population with low prevalence, even a high-sensitivity test may lead to a high percentage of false positive diagnoses, resulting in the need for multiple high-cost tests to achieve a correct diagnosis. […] Thus, basing a policy for opening airports on diagnostic testing, even with the best test for COVID-19, has some limits. | 2020-08-15 |
| 32792046 | Diagnosis is based on the combination of a history of exposure, clinical presentation, and real-time polymerase chain reaction (RT-PCR) assays. […] In endemic areas, imaging tests including computed tomography (CT), chest X-ray (CXR), and ultrasound (US) have been included in the diagnostic workup. | 2020-08-15 |
| 32792263 | The more sensitive cell-free fetal DNA test was commonly used to screen for aneuploidy in an effort to decrease return visits for diagnostic genetic procedures. | 2020-08-15 |
| 32792455 | The e-mental health intervention ‘CoPE It’ consists of four 30 min modules, conducted every other day, involving psychotherapeutic techniques of mindfulness-based stress reduction and cognitive-behavioural therapy. | 2020-08-15 |
| 32793434 | The vast knowledge about the pathways that regulate the virus entry and molecular signaling of the pathogenesis of coronavirus are the key factor for the development of de novo diagnostic/therapeutic strategies. | 2020-08-15 |
| 32793618 | The more common causes of morbidity and death in these patients include pneumonia and respiratory failure, which cause the patients to require artificial ventilation and other techniques that can improve respiratory function. […] One of these techniques is chest physiotherapy, and this has been shown to improve gas exchange, reverse pathological progression, and reduce or avoid the need for artificial ventilation when it is provided very early in other respiratory conditions. | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793722 | We thus performed a systematic review and meta-analysis based on the best available studies to estimate the prevalence and identify the underlying differential diagnostic value of VES. […] The methodologic quality was assessed using Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2). | 2020-08-15 |
| 32793981 | In this research, an automated system is created to differentiate between the COVID-19, SARS-CoV and MERS-CoV epidemics by using their genomic sequences recorded in the NCBI GenBank in order to facilitate the diagnosis process and increase the accuracy of disease detection in less time. | 2020-08-15 |
| 32794002 | To determine prevalence, severity, duration, and time from onset to diagnosis of general and Otorhinolaryngologic symptoms related to COVID-19 in whole disease spectrum: from mild to critical patients. […] Symptom durations and onset time to diagnosis varied. | 2020-08-15 |
| 32794035 | To assure the proper protection without overuse of limited supply of these equipments, screening of patients before surgical or diagnostic procedure was implemented. | 2020-08-15 |
| 32794042 | For COVID-19, predictive modeling, in the literature, uses broadly SEIR/SIR, agent-based, curve-fitting techniques/models. […] Besides, machine-learning models that are built on statistical tools/techniques are widely used. | 2020-08-15 |
| 32794113 | Data extraction included diagnosis, demographics, immunosuppressive treatment, comorbidities, and laboratory tests. […] There were no statistically significant between-group differences for rheumatologic diagnosis and for baseline use of immunosuppressive therapy except for glucocorticoids that were more frequent in hospitalized patients. | 2020-08-15 |
| 32794453 | Virus nucleic acid real-time RT-PCR testing has become the current standard diagnostic method but high demand could lead to shortages. […] All diagnostic primers are species-specific since the 3´ end of the sequence differs from that of other species. […] Amplification was achieved for the positive control and specific regions in both techniques. […] It has the advantage that if the coronavirus mutates in one of the key amplification nucleotides, at least one pair can still amplify, thanks to the four diagnostic primers. | 2020-08-15 |
| 32794460 | During pandemic COVID-19 was the main concern in every clinic and as we discuss here overlapping respiratory diseases may result in delaying of the diagnosis and treatment. […] The Xpert Ultra assay was performed for the diagnosis of pulmonary tuberculosis; SARS-CoV-2 RNA was determined by real-time PCR (RT-PCR) analysis in combined nasopharyngeal and deep oropharyngeal swabs of suspected cases of COVID-19. […] One patient already diagnosed with tuberculosis become COVID-19 positive during hospitalization and another patient suspected and treated for COVID-19 received the final diagnosis of pulmonary TB and Human Immunodeficiency Virus infection. | 2020-08-15 |
| 32794464 | All patients confirmed as having COVID-19 between 23 January and 25 March 2020 by RT-PCR assay in the clinical lab of Shantou CDC were included and divided into three groups based on the source of identification: hospital diagnosis, contact tracing, and community screening. […] The median lag time for diagnosis (i.e., the time between symptom onset and case confirmation) was 2 days (IQR, 2.0-4.0) for all cases, 9 days (IQR, 7.0-10.0) for the cases diagnosed in hospitals, 2 days (IQR, 1.5-2.0) for the cases in contact tracing, and 4 days (IQR, 2.5-4.5) for cases in community screening, with a significantly longer diagnosis lag time in hospitals (p = 0.003). | 2020-08-15 |
| 32794466 | Limited published clinical data, scarcity and long turn over time of diagnostic testing put clinician in dilemma to make diagnosis. | 2020-08-15 |
| 32794674 | On the basis of the latest literature and evidence-based medical evidence on the fight against COVID-19 epidemic and steroid ONFH diagnosis and treatment, the Bone Circulation and Osteonecrosis Professional Committee, Shockwave Medical Specialty Committee of Chinese Research Hospital Association organized Chinese bone necrosis related experts to jointly write this consensus, focusing on the prevention strategy and the protective management measures in the ONFH diagnosis and treatment process during the prevention and control of COVID-19, which can provide reference for hospitals at all levels to carry out early prevention and treatment of ONFH. | 2020-08-15 |
| 32795131 | Previously, discharged patients with coronavirus disease 2019 (COVID-19) patients met the criteria of China’s pneumonia diagnosis and treatment program of novel coronavirus infection (trial version 7) for cure of viral infection. | 2020-08-16 |
| 32795225 | We hypothesized that cytotoxic chemotherapy administered within 35 days of a COVID-19 diagnosis is associated with an increased hazard ratio (HR) of severe or critical COVID-19. […] Lymphopenia at COVID-19 diagnosis was associated with higher rates of severe or critical illness (HR, 2.10; 95% CI, 1.50 to 3.10). […] Patients with baseline neutropenia 14-90 days before COVID-19 diagnosis had worse outcomes (HR, 4.20; 95% CI, 1.70 to 11.00). | 2020-08-16 |
| 32795495 | All higher-risk exposures to infected patients occurred on non-COVID-19 units, often when there was a delay in diagnosis because COVID-19 was not initially suspected. | 2020-08-16 |
| 32795547 | The most important aspect of controlling COVID-19 is its timely diagnosis. […] Molecular diagnostic tests target the detection of any of the following markers such as the specific region of the viral genome, certain enzyme, RNA-dependent RNA polymerase, the structural proteins such as surface spike glycoprotein, nucleocapsid protein, envelope protein, or membrane protein of SARS-CoV-2. […] This review highlights the underlying mechanisms, advancements, and clinical limitations for each of the diagnostic techniques authorized by the Food and Drug Administration (USA). […] Significance of diagnosis triaging, information on specimen collection, safety considerations while handling, transport, and storage of samples have been highlighted to make medical and research community more informed so that better clinical strategies are developed. […] Having a comprehensive knowledge of the diagnostic approaches of SARS-CoV-2, and its pathogenesis will be of great value in designing a long-term strategy to tackle COVID-19. | 2020-08-16 |
| 32796159 | In order for public health, care delivery systems, clinicians and other stakeholders to be better prepared for the next wave of SARS-CoV-2 infections, which, at this point, seems inevitable, we need to better understand this disease-not only from a clinical diagnosis and treatment perspective-but also from a forecasting, planning, and advanced preparedness point of view. | 2020-08-16 |
| 32796214 | Patients’ characteristics and median days between symptoms and diagnosis were similar by hospital admission, whereas admitted patients had lower nadir CD4 cells and current lymphocytes count. | 2020-08-16 |
| 32796217 | Mean C-reactive protein, ferritin, erythrocyte sedimentation rate and lactate dehydrogenase levels after COVID-19 diagnosis were not statistically different and mortality was not different for PLH with a history of antiretroviral treatment. […] Early diagnosis and intensive surveillance are needed to prevent a ‘Syndemic’ of diseases in this vulnerable cohort. | 2020-08-16 |
| 32796445 | The impact of age, sex, visual function and diagnosis on the AtT rate during unlocked/locked weeks (from March 8) was evaluated. | 2020-08-16 |
| 32796791 | Besides, due to the rapid diffusion of the viral infection, there are already alarms on how to deal with the psychiatric aspects of COVID-19 pandemic in persons with an established diagnosis of psychiatric disorders, staff, and those in self-isolation. | 2020-08-16 |
| 32796796 | This work gives an overview of the multi-dimensional and trans-disciplinary techniques, which can be helpful to cope up with the crises that emerged from the threat of COVID-19 Outbreak for victims, survivors, health care practitioners and community. | 2020-08-16 |
| 32796800 | Seeking social support is more pronounced in those over 40 years old, while those under 40 use more avoidable stress management techniques. | 2020-08-16 |
| 32796848 | Chest CT is emerging as a valuable diagnostic tool for clinical management of COVID-19 associated lung disease. | 2020-08-16 |
| 32797188 | A recent study of 423 patients at our institution found that patients in active cancer treatment who develop COVID-19 infection did not fare any worse than other hospitalized patients yet guidance as to who requires testing prior to antineoplastic therapy and when to resume therapy post-COVID diagnosis remains unknown. | 2020-08-16 |
| 32797641 | At present, the only reliable test for COVID-19 diagnosis is quantitative reverse transcriptase-polymerase chain reaction. […] One hundred samples obtained from COVID-19 negative subjects (COVID-19 free) were analyzed to evaluate the diagnostic specificity of antibody (Ab) detection. […] Thereafter, 176 samples obtained from 125 patients with confirmed COVID-19 (COVID-19 patients) were selected to assess the diagnostic sensitivity of the CLIA. […] Hence, the diagnostic specificity was estimated at 100% (95% confidence interval [CI] = 96.3-100.0; positive predictive value = 100%). […] By the 18th day from the onset of symptoms, we reached an optimal diagnostic sensitivity (more than 95.0%) In fact, the diagnostic sensitivity increased over time and between 15 and 25 days after symptoms onset, reached 95.5% (95% CI = 84.9-99.2). […] Our data suggest that combining Ab and nucleic acid detection could increase diagnostic sensitivity. | 2020-08-16 |
| 32798097 | This study aimed to assess whether youth cigarette and electronic cigarette (e-cigarette) use are associated with coronavirus disease 2019 (COVID-19) symptoms, testing, and diagnosis. […] Multivariable logistic regression assessed relationships among COVID-19-related symptoms, testing, and diagnosis and cigarettes only, e-cigarettes only and dual use, sociodemographic factors, obesity, and complying with shelter-in-place. […] COVID-19 diagnosis was five times more likely among ever-users of e-cigarettes only (95% confidence interval [CI]: 1.82-13.96), seven times more likely among ever-dual-users (95% CI: 1.98-24.55), and 6.8 times more likely among past 30-day dual-users (95% CI: 2.40-19.55). | 2020-08-17 |
| 32798104 | From 151 consultations, 149 (98.7%) successfully established a working diagnosis and treatment plan and/or concluded an episode of patient care, without the need to convert to a face-to-face encounter between clinician and patient. | 2020-08-17 |
| 32798170 | The objective of these recommendations is to make changes to some routine techniques in thoracic anesthesia to augment patients’ and the medical staff’s safety. | 2020-08-17 |
| 32798248 | Diagnostic sensitivity and reproducibility were evaluated using artificial SARS-CoV-2. […] Diagnostic performance was evaluated by testing two sputum and nine oropharyngeal swab specimens. […] The overall agreement value between the SARS-CoV-2 RT-PCR assay and clinical diagnostic results was 100%. | 2020-08-17 |
| 32798300 | The technique is divided into the phases: extraction of knowledge in natural language about assessment, planning and intervention, translation into standard language NOC and NIC, linking to NANDA-I diagnoses, triangulation looking for diagnostic matches in the three sets, and, finally, validation by a panel of experts from a hospital and a university. […] The results of this study may guide the diagnosis and treatment of coronavirus disease, COVID-19, as well as similar processes that occur with acute respiratory distress syndrome. | 2020-08-17 |
| 32798472 | Of the 61 414 470 individuals who were alive and registered with a general practice on Feb 16, 2020, 263 830 (0·4%) had a recorded diagnosis of type 1 diabetes, 2 864 670 (4·7%) had a diagnosis of type 2 diabetes, 41 750 (0·1%) had other types of diabetes, and 58 244 220 (94·8%) had no diabetes. 23 698 in-hospital COVID-19-related deaths occurred during the study period. | 2020-08-18 |
| 32798473 | This multicentre, retrospective, cohort study included adult patients (aged ≥18 years) with diagnosis of a WHO-defined haematological malignancy admitted to 66 Italian hospitals between Feb 25 and May 18, 2020, with laboratory-confirmed and symptomatic COVID-19. […] Older age (hazard ratio 1·03, 95% CI 1·01-1·05); progressive disease status (2·10, 1·41-3·12); diagnosis of acute myeloid leukaemia (3·49, 1·56-7·81), indolent non-Hodgin lymphoma (2·19, 1·07-4·48), aggressive non-Hodgkin lymphoma (2·56, 1·34-4·89), or plasma cell neoplasms (2·48, 1·31-4·69), and severe or critical COVID-19 (4·08, 2·73-6·09) were associated with worse overall survival. | 2020-08-18 |
| 32798514 | To provide a better understanding of the importance of abnormal laboratory findings in COVID-19 diagnosis and prognosis, we searched the Scopus, PubMed, and Web of Science medical databases and selected 19 articles (totaling 2988 patients, 484 of whom [16.1%] had severe disease) that reported panels of laboratory examinations in patients with COVID-19. | 2020-08-18 |
| 32798922 | We enrolled patients with a COVID-19 diagnosis who were admitted to five United States health systems between March 24 and May 4, 2020. 197 patients were enrolled in the REspirAtory Decompensation and model for the triage of covid-19 patients: a prospective studY (READY) clinical trial. […] The algorithm had a higher diagnostic odds ratio (DOR, 12.58) for predicting ventilation than a comparator early warning system, the Modified Early Warning Score (MEWS). | 2020-08-18 |
| 32798931 | Young subjects who have been followed up with a primary diagnosis of OCD in a university hospital were reached by telephone or online programs to assess symptom profile, symptom severity and exacerbation during pandemic. […] There was a significant relationship between the change in CY-BOCS scores with talking/searching in the social environment about COVID-19, daily preoccupation about COVID-19, duration of OCD diagnosis and diagnosis of COVID-19 in someone familiar. | 2020-08-18 |
| 32799107 | Logistic-regressions analyses mainly revealed that women, young individuals, having a previous psychiatric diagnosis or trauma, having high levels of trait-neuroticism and COVID-related fear, were those at greater risk of psychological distress. | 2020-08-18 |
| 32799213 | These findings may help in the early detection and diagnosis of neuro-COVID-19, especially among clinicians and neurologists working in areas of endemic SARS-CoV-2 infection. | 2020-08-18 |
| 32799308 | We compared parameters including a critical illness as the discharge diagnosis (e.g., myocardial infarction, stroke, sepsis and ER death) using logistic and linear regression, as well as 15-day bootstrapped means and 95% confidence intervals for the control group. […] Apart from polytrauma (increase of 5% in the mp), all other critical illnesses as discharge diagnosis showed a lower incidence in descriptive analysis. | 2020-08-18 |
| 32799337 | Additional clinical data were obtained in patients with a COVID-19 diagnosis. | 2020-08-18 |
| 32799883 | Our core idea is that “active cancer” may be considered a proxy of more recent exposure to diagnostic or therapeutic procedures, and the frequency of access to health care facilities can be predicted as a function of the severity of cancer symptoms. | 2020-08-18 |
| 32800031 | Epidemiological contact history, imaging examination findings, and viral nucleic acid testing results are important bases for the diagnosis of COVID-19. | 2020-08-18 |
| 32800295 | Baseline D-dimer abnormalities (4,647.0 ± 8,281.8) were noted on admission with a 3-fold increase at the time of PE diagnosis (13,288.4 ± 14,917.9; p <0.05). | 2020-08-18 |
| 32800517 | Kidney allograft biopsy is the gold standard for diagnosis of rejection. | 2020-08-18 |
| 32800720 | A total of 218 patients (13%) received a diagnosis of possible COVID-19, with SARS-CoV-2 infection confirmed in 18.4%, and 23.8% (52/218) were hospitalised. | 2020-08-18 |
| 32800760 | The recommendation for the majority of the pharmacological treatments used in rheumatology is to continue with immunomodulatory or immunosuppressive therapies in patients who do not have the infection, and to suspend it in patients with a diagnosis of SARS-CoV-2/COVID-19. | 2020-08-18 |
| 32801207 | The ability of lung ultrasound (LUS) and its evolving applications in the diagnosis of COVID-19 pneumonia are widespread. […] This study aims to evaluate the surveillance value of LUS in the diagnosis of COVID-19 pneumonia. […] We will search Ovid Medline, Ovid Embase, Web of Science, Cochrane Library, Scopus, Google Scholar, China Biology Medicine disc and WHO Global Health Library for studies on diagnostic accuracy from December 2019 to April 2021. […] The assessment of risk of bias for each outcome will be conducted using the QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2) tool. | 2020-08-18 |
| 32801291 | Because it is a life-threatening condition, rapid diagnosis is necessary to prevent acute complications. […] Diagnostic criteria for rhabdomyolysis are elevated serum creatine kinase, liver enzyme levels, and myalgia. | 2020-08-18 |
| 32801413 | Several diagnostic modalities have been advocated and evaluated; however, in some cases, diagnosis is made on the clinical picture in order not to lose time. | 2020-08-18 |
| 32801737 | This paper outlines the biological and epidemiological characteristics and diagnosis of CoVs and describes the origin, transmission route, animal-source food risk, and control measures for CoVs. | 2020-08-18 |
| 32801800 | During the epidemic period of SARS-CoV-2 infection, when presenting patients with ageusia and anosmia, physicians should consider COVID-19 pneumonia as a differential diagnosis to achieve early identification, avoid the delayed diagnosis, and prevention of transmission. | 2020-08-18 |
| 32801804 | One of the critical issues to be addressed is the improvement in laboratory diagnosis and screening of large portions of the population to stop the virus spreading. […] Currently, the laboratory diagnosis of SARS-CoV-2 infection and the related disease is based on the research of viral RNA with rt-PCR methods in upper and lower respiratory airways. […] Serological tests to detect SARS-CoV-2 antibodies could help physicians and healthcare workers to support COVID-19 diagnosis and follow-up and perform population screening. | 2020-08-18 |
| 32801842 | The diagnosis is mainly based on the use of polymerase chain reaction for the detection of viral ribonucleic acid in the sputum or tracheal fluids. | 2020-08-18 |
| 32801943 | This is the first report from Iran that presented two cases of liver transplantation with COVID-19, neither of which had pulmonary signs and symptoms, but after diagnostic imaging, both had lung involvement. | 2020-08-18 |
| 32802003 | The keywords included in assessment of COVID-19 related information using Google’s search engine were “Coronavirus,” “Coronavirus causes,” “Coronavirus diagnosis,” “Coronavirus prevention,” and “Coronavirus management”. | 2020-08-18 |
| 32802146 | This study is aimed at comparing the confusion regarding the selection of effective diagnostic methods to make a mutual comparison among existing SARS-CoV-2 diagnostic tests and at determining the most effective one. […] Based on available published evidence and clinical practice, diagnostic tests of coronavirus disease (COVID-19) were evaluated by multi-criteria decision-making (MCDM) methods, namely, fuzzy preference ranking organization method for enrichment evaluation (fuzzy PROMETHEE) and fuzzy technique for order of preference by similarity to ideal solution (fuzzy TOPSIS). […] Computerized tomography of chest (chest CT), the detection of viral nucleic acid by polymerase chain reaction, cell culture, CoV-19 antigen detection, CoV-19 antibody IgM, CoV-19 antibody IgG, and chest X-ray were evaluated by linguistic fuzzy scale to compare among the diagnostic tests. […] The results of our study with both proposed MCDM methods indicated that the most effective diagnosis method of COVID-19 was chest CT. […] It is interesting to note that the methods that are consistently used in the diagnosis of viral diseases were ranked in second place for the diagnosis of COVID-19. […] However, each country should use appropriate diagnostic solutions according to its own resources. […] Our findings also show which diagnostic systems can be used in combination. | 2020-08-18 |
| 32802606 | Although acute pancreatitis is rare in patients with COVID-19, it should be considered as a differential diagnosis in patients with severe epigastric pain and respiratory symptoms. | 2020-08-18 |
| 32802742 | Persian medicine techniques may be preventive during respiratory, influenza-like disease pandemics. | 2020-08-18 |
| 32802747 | This is especially worrisome in the context of the pandemic, where COVID-19 positive patients must be promptly identified, isolated and contact-traced, and eluded diagnosis might possibly endanger communities and healthcare workers. | 2020-08-18 |
| 32803472 | For mental health, heightened stress responses to the pandemic, is likely to manifest in three ways: 1) development of a new episode of a disorder in those with a predisposition to a major psychiatric disorder or an acute exacerbation in those who already have such a disorder, 2) development of a trauma or stressor related disorder, such as acute stress disorder, Post Traumatic Stress Disorder (PTSD), or adjustment disorders, and 3) development of a symptomatic stress response that does not meet the diagnostic criteria of a psychiatric disorder. | 2020-08-18 |
| 32803670 | In this review, we discuss the most updated evidence on the pathophysiology, diagnosis, and treatment of the coagulopathy of COVID-19. | 2020-08-18 |
| 32804081 | Compared to COVIDneg patients at the time of diagnostic testing, COVIDpos patients tended to have higher plasma fibrinogen levels and lower platelet counts. | 2020-08-18 |
| 32804112 | CT plays an important role in disease diagnosis and early intervention. | 2020-08-18 |
| 32804317 | In this single-center, retrospective observational study, we included all adult patients (> 18 years old) admitted to Einstein Medical Center, Philadelphia, with a diagnosis of COVID-19. […] Patients were classified according to having a known diagnosis of diabetes mellitus. | 2020-08-18 |
| 32804431 | We included 102 unselected individuals with a diagnosis of TSC and/or LAM assessed between January 1, 2020 and April 24, 2020 (29% children, 71% adults). | 2020-08-18 |
| 32804580 | To investigate the value of the combined detection of the neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein level (CRP) in the diagnosis of COVID-19. […] Our results showed that the NLR and CRP were independent risk factors for COVID-19, and the combined detection of the NLR and CRP showed improved diagnostic performance for COVID-19. | 2020-08-18 |
| 32804668 | Decisions on diagnostic use should include considerations on the lod. | 2020-08-18 |
| 32804682 | Vitamin D supplementation in patients after diagnosis of COVID-19. | 2020-08-18 |
| 32804760 | A retrospective review of the recent clinical history of patients in association with the typical pulmonary images on CT scan suggested the diagnosis of COVID-19. | 2020-08-18 |
| 32804802 | More than one-third of patients showed digestive symptoms at diagnosis, combinations of nausea, vomiting and diarrhea. | 2020-08-18 |
| 32804920 | It should be considered in the differential diagnosis in patients who arrives at the emergency with a sensory disorder or neurological symptomatology in the context of the COVID-19 pandemic. | 2020-08-18 |
| 32804922 | We present a series of six cases of doctors infected by SARS-CoV-2, with confirmed positivity for COVID-19, showing the daily evolution from the diagnosis of the disease, its main signs and symptoms, evolution, and until the outcome in each case. […] The diagnosis was made at a median of 3 days (interquartile range: 3 to 4 days). | 2020-08-18 |
| 32805515 | The study also showed the utility of immunohistochemistry in the diagnostic pathology laboratory for elucidating this information. […] Six additional cases of human tuberculosis with few organisms showed that the viral envelope specific antibody (5/6) was more accurate than the AFB stain (2/6) for diagnostic purposes. […] The data also suggests the value of using the SARS-CoV-2 envelope antibody in the diagnosis of Mycobacterial infections in formalin fixed, paraffin embedded tissues by the diagnostic pathologist. | 2020-08-18 |
| 32805702 | Future studies are needed to provide additional data to guide optimal VTE prophylaxis and diagnostic strategies. | 2020-08-18 |
| 32805728 | The clinical diagnosis of patients with COVID-19 has risen sharply, especially in Western countries. | 2020-08-18 |
| 32806776 | Deep knowledge of the genetic features of SARS-CoV-2 is essential to track the ongoing pandemic through different geographical areas and to design and develop early diagnostic procedures, therapeutic strategies, public health interventions, and vaccines. | 2020-08-19 |
| 32807209 | We will enrol adults, ≥ 18 years of age assessed in acute hospitals in the UK with clinical diagnosis of COVID-19 infection where management on an ambulatory care pathway is deemed appropriate. […] Secondary objectives include mortality/respiratory failure in those with a PCR-confirmed diagnosis; all-cause mortality; progression to pneumonia; progression to severe pneumonia; peak severity of illness and mechanistic analysis of blood and nasal biomarkers. | 2020-08-19 |
| 32807241 | Positive SARS-CoV-2 diagnostic (on pharyngeal swab of deep airways material) 2. | 2020-08-19 |
| 32807244 | Different countries have adopted strategies for the early detection of SARS-CoV-2 since the declaration of community transmission by the World Health Organization (WHO) and timely diagnosis has been considered one of the major obstacles for surveillance and healthcare. […] Here, we report the increase of the number of laboratories to COVID-19 diagnosis in Brazil. | 2020-08-19 |
| 32807396 | There currently lacks a study that showcases the novelty of daily COVID-19 surveillance using space-time cluster detection techniques. | 2020-08-19 |
| 32807425 | Aneurysmal subarachnoid hemorrhage (SAH) patients require frequent neurological examinations, neuroradiographic diagnostic testing and lengthy intensive care unit stay. | 2020-08-19 |
| 32807471 | A total of 754 patients (pandemic-120; pre-pandemic-634) were admitted with a principal diagnosis of AIS; 198 (26.3%) received alteplase and/or mechanical thrombectomy. | 2020-08-19 |
| 32807570 | Computed tomography (CT) is the routine imaging technique for diagnosis and monitoring of COVID-19 pneumonia. […] Chest CT has high sensitivity for diagnosis of COVID-19, but is not universally available, requires an infected or unstable patient to be moved to the radiology unit with potential exposure of several people, necessitates proper sanification of the CT room after use and is underutilized in children and pregnant women because of concerns over radiation exposure. […] The increasing frequency of confirmed COVID-19 cases is striking, and new sensitive diagnostic tools are needed to guide clinical practice. […] LUS has been found to be a promising tool for the diagnosis of COVID-19 pneumonia, and LUS findings correlate fairly with those of chest CT scan. […] Consequently, LUS may decrease utilization of conventional diagnostic imaging resources (CT scan and chest X-ray). […] LUS may help in early diagnosis, therapeutic decisions and follow-up monitoring of COVID-19 pneumonia, particularly in the critical care setting and in pregnant women, children and patients in areas with high rates of community transmission. | 2020-08-19 |
| 32807944 | Our findings could be used to develop second-generation diagnostic tests to improve serological assays for COVID-19 and are important in understanding pathogenicity. | 2020-08-19 |
| 32808010 | Use of spatial analysis techniques is suggested to identify spatial disease patterns and to provide spatially disaggregated public health policy recommendations. | 2020-08-19 |
| 32808079 | Our current study aimed to identify specific COVID-19 18F-FDG-PET signs in patients that were (i) suspected to have a lung infection based on 18F-FDG-PET/CT recorded during the COVID-19 outbreak and (ii) whose COVID-19 diagnosis was definitely established or excluded by appropriate viral testing. […] All patients had undergone a SARS-COV-2 diagnostic test to confirm COVID-19 infection (positivity was based on molecular and/or serological tests) or exclude it (negativity of at least the serological test). | 2020-08-19 |
| 32808174 | Its diagnosis might be challenging. […] Clinical presentation and diagnostic work-up of the patients. | 2020-08-19 |
| 32808273 | The pattern of WMDs on neuroimaging can be an important clue to the final diagnosis. […] While paediatric WMDs have a well-defined and literature-based clinical-laboratory approach to diagnosis, adult-onset WMDs remain an important, pathologically diverse, radiographic phenotype, with different and distinct neuropathologies among the various subtypes of WMD. | 2020-08-19 |
| 32808446 | Various diagnostic approaches were developed and implemented to assist in the rapid identification of patients and treatment of their illness, yet many of the approaches required days or weeks from the onset of fever to show statistical significance. | 2020-08-19 |
| 32808545 | To investigate the diagnostic performance of chest CT in screening patients suspected of Coronavirus disease 2019 (COVID-19) in a Western population. […] Our study shows that chest CT interpreted by frontline general radiologists achieves insufficient diagnostic performance to use it as an independent screening tool for COVID-19. | 2020-08-19 |
| 32808759 | The proposed method uses a developed breath device composed of a nanomaterial-based hybrid sensor array with multiplexed detection capabilities that can detect disease-specific biomarkers from exhaled breath, thus enabling rapid and accurate diagnosis. […] The proposed method can be considered as a platform that could be applied for any other disease infection with proper modifications to the artificial intelligence and would therefore be available to serve as a diagnostic tool in case of a new disease outbreak. | 2020-08-19 |
| 32808808 | Studies have demonstrated the diagnostic efficiency of antibody testing in COVID-19 infection. | 2020-08-19 |
| 32808850 | In this review, we discuss the virological, immunological, and imaging approaches harnessed for COVID-19 diagnosis and research. […] We summarize the available literature on current laboratory and point-of-care diagnostics, highlight their strengths and limitations, and describe the emerging diagnostic approaches on the horizon.We also discuss the various research techniques that are being used to evaluate host immunity in laboratory-confirmed patients. […] Conventional techniques, such as immunohistochemistry and immunofluorescence, have been frequently used to characterize the immune microenvironment in COVID-19. […] We also outline the emerging imaging techniques, such as the RNAscope, which might also aid in our understanding of the significance of COVID-19-specific biomarkers, such as the angiotensin-converting enzyme 2 (ACE2) cellular receptor.Overall, great progress has been made in COVID-19 research in a short period. | 2020-08-19 |
| 32809036 | There is still no standard procedure for the postmortem radiological diagnosis of COVID-19 disease. | 2020-08-19 |
| 32809060 | Patients enrolled were > 18 years of age; had a diagnosis of cancer; and were able to complete the emailed study survey online. | 2020-08-19 |
| 32809211 | More evidence is urgently needed to better evaluate the need for protective measures and reliable ocular diagnostic tests to diminish further pandemic spread. | 2020-08-19 |
| 32809292 | Clinicians should consider COVID-19 in their differential diagnosis with any patient who presents with psychotic symptoms, even in the absence of the typical COVID-19 symptoms of cough or fever. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810426 | Nasopharyngeal swab and a chest radiograph were performed in all patients within 48 hours before the surgical procedure: in the suspected cases with negative COVID tests, we prudently postponed surgery and repeated the diagnostic tests after 15 days. | 2020-08-19 |
| 32810610 | This retrospective study from a University tertiary care hospital in northern Italy, included hospitalized adult patients with a diagnosis of COVID-19 between 25 February 2020 and 25 March 2020. […] Common symptoms at the time of COVID-19 diagnosis included fever (285/317; 89.9%), shortness of breath (167/317; 52.7%) and dry cough (156/317; 49.2%). | 2020-08-19 |
| 32810701 | To evaluate the diagnostic and prognostic performance of CT in patients referred for COVID19 suspicion to a French university hospital, depending on symptoms and date of onset. | 2020-08-19 |
| 32810844 | First, the diagnosis has been delayed due to social isolation, reduced access to investigations and staff redeployment. | 2020-08-19 |
| 32810953 | Conclusions: The COVID-19 epidemic has effect on the integrated treatment of CRC patients include diagnosis, treatment, examination and prognosis. | 2020-08-19 |
| 32811274 | We performed a timely analysis of the Bavarian telestroke TEMPiS “working diagnosis” database. | 2020-08-20 |
| 32811575 | Preliminary evidence from the rapidly progressing field of psychedelic science shows that psilocybin therapy offers a promising transdiagnostic treatment strategy for a range of disorders with restricted and maladaptive habitual patterns of cognition and behaviour, notably depression, addiction and obsessive compulsive disorder. | 2020-08-20 |
| 32811680 | The result of the teleconsultation was classified as discharge, resolved visit or reprogramming and was analysed by different diagnostic groups. […] The diagnostic categories of the patients attended were: 51 (26.9%) colorectal neoplasia, 48 (25.3%) proctological pathology, 72 (37.9%) pelvic floor dysfunctions and 19 (10%) other benign pathologies. […] No significant differences were found between the different diagnostic categories and the resolution of the teleconsultation. | 2020-08-20 |
| 32811804 | Because clinical diagnosis of ARDS includes several diseases, understanding the characteristics of COVID-19-related ARDS is necessary for precise treatment. […] Six days after symptom onset, reverse transcription-polymerase chain reaction (RT-PCR) testing confirmed the diagnosis of COVID-19-associated pneumonia. | 2020-08-20 |
| 32811936 | The intention of the protocol is to describe practical techniques to minimise potential viral load and reduce risk of COVID-19 transmission when AGPs are instigated. | 2020-08-20 |
| 32812365 | At this time, diagnosis is based on the positivity of specific RT-PCR and/or chest computed tomography scan, which are time-consuming and may delay diagnosis. […] Complete blood count (CBC) can potentially contribute to the diagnosis of COVID-19. […] Consideration of CPD could constitute a first step and potentially aid in the early diagnosis of COVID-19. | 2020-08-20 |
| 32812619 | The COVID-19 pandemic has sparked a demand for safe and highly effective decontamination techniques for both personal protective equipment (PPE) and hospital and operating rooms. […] Ultraviolet C (UVC) radiation has well-known germicidal properties and is among the most frequently reported decontamination techniques used today. | 2020-08-20 |
| 32812872 | Level III, Diagnostic study. | 2020-08-20 |
| 32813105 | To assess the diagnostic performances of chest CT for triage of patients in multiple emergency departments during COVID-19 epidemic, in comparison with reverse transcription polymerase chain reaction (RT-PCR) test. | 2020-08-20 |
| 32813110 | Technological advances in recent years have resulted in the development and implementation of various modalities and techniques enabling medical professionals to remotely diagnose and treat numerous medical conditions in diverse medical fields, including ophthalmology. […] Therefore, utilizing remote care in the daily workflow would be a valuable tool for the diagnosis and treatment of acute and chronic ocular conditions in this challenging clinical setting. […] We present them as well as potential diagnostic and treatment applications in view of the recent SARS-CoV-2 virus outbreak. | 2020-08-20 |
| 32813575 | There has been a surge in demand for COVID-19 diagnostic reagents, as timely detection of virus carriers is one of the most important components of disease prevention and control. […] Nucleic acid testing (NAT), with high sensitivity and specificity, is considered the “gold standard” for the diagnosis of COVID-19. […] This has resulted in chaos in the clinical diagnosis of COVID-19. | 2020-08-20 |
| 32813683 | However, in a patient with concomitant pulmonary tuberculosis, it can be a diagnostic challenge. […] A co-infection of pulmonary and CNS TB with COVID-19 can present a diagnostic challenge, and appropriate patient management relies on an accurate and rapid diagnosis. […] A diagnosis of COVID-19 should not delay urgent surgeries. | 2020-08-20 |
| 32813760 | Results A total of 510 patients with a confirmed diagnosis of COVID-19 were included in this study. | 2020-08-20 |
| 32813814 | Further data on accuracy of COVID-19 diagnostic test are urgently warranted. | 2020-08-20 |
| 32813843 | We were unable to find any review of the literature or analysis on ongoing registered clinical trials that reported diagnostic tests, therapeutics, vaccines and devices for COVID-19 along with estimated enrollment, participants’ ages, study type, start and completion date, status, treatment/intervention and country. […] They were mostly on drugs and treatment, while a minority were on diagnostic tests. […] The trials identified were categorized into five classes: a) diagnostic tests; b) therapeutics; c) biologics and vaccines; d) devices and products; and e) others. | 2020-08-20 |
| 32814591 | The practices could be categorized into active case surveillance, rapid case diagnosis and management, strict follow-up and quarantine of persons with close contacts, and issuance of guidance to help the public understand and adhere to control measures, plus prompt and effective high-level policy decision, complete activation of the public health system, and full involvement of the society. | 2020-08-21 |
| 32814634 | Neuroaxial techniques appear to be safe and it is important to obtain the highest possible rate of success of the blocks before a cesarean section. | 2020-08-21 |
| 32814650 | During the first 3 months of the epidemic in Qom, Iran, 24 children with confirmed diagnosis of COVID-19 were included. | 2020-08-21 |
| 32814757 | However, pediatric clinical signs are less severe, making the onset diagnosis challenging to interpret. […] A real-time polymerase chain reaction test was positive, confirming the initial diagnostic hypothesis. | 2020-08-21 |
| 32814926 | The main clinical characteristics of COVID-19 patients are revised here as compared to other coronavirus infections, such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS), emphasizing clinical, diagnostic and therapeutic aspects. | 2020-08-21 |
| 32815174 | Rapid diagnosis, isolation, and intensive clinical management are very important for all patients with COVID-19, especially for those with cardiac diseases as Brugada syndrome (BrS). | 2020-08-21 |
| 32815351 | Primary care doctors put diagnostic codes on all reimbursement cards. […] The objective of this study was to map out the use of non-specific diagnostic codes that can undermine the validity of statistics and disease surveillance. […] We registered consultations and telephone contacts and the proportion of these that were supplied with diagnostic codes for respiratory infections and three non-specific diagnostic codes. […] There is a strong tendency for general, non-specific diagnostic codes to replace specific diagnoses of disease on reimbursement cards from out-of-hours services. | 2020-08-21 |
| 32815356 | Thirty-seven of the residents had atypical symptoms, nine of them were asymptomatic at the time of diagnosis, and 21 died during the coronavirus infection. | 2020-08-21 |
| 32815458 | Culture accompanied with metagenomics sequencing increased pathogen diagnostic rate. | 2020-08-21 |
| 32815519 | Chest X-ray plays a key role in diagnosis and management of COVID-19 patients and imaging features associated with clinical elements may assist with the development or validation of automated image analysis tools. | 2020-08-21 |
| 32815523 | The chest computed tomography (CT) has an important complementary role in diagnosis of the disease. […] CT imaging also guides in differentiation of alternative diagnosis or in assessment of associated pulmonary embolism during the course of the disease. | 2020-08-21 |
| 32815744 | PCR has become one of the most valuable techniques currently used in bioscience, diagnostics and forensic science. […] We also discuss the commercialization of these techniques and conclude with a look into their modifications and use in innovative areas of biomedicine. | 2020-08-21 |
| 32815827 | We retrieved demographic data, diagnosis, and outcomes from the electronic health care records of all patients admitted to the ICU between March 1, 2020 and April 30, 2020. | 2020-08-21 |
| 32816114 | This counts as a German case since her diagnosis was eventually made in Munich (Germany) on 28 January. | 2020-08-21 |
| 32816387 | Health care workers (HCWs) on frontline directly participated in the diagnosis, treatment, and care of COVID-19 patients are at high risk of getting infected with the highly infectious severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the novel coronavirus that causes COVID-19. | 2020-08-21 |
| 32816437 | Diagnosis On investigation with CT, duodenojejunitis was diagnosed as the cause of abdominal pain. | 2020-08-21 |
| 32816680 | Timely diagnosis of COVID-19 is crucial both for disease control and patient care. […] Non-contrast thoracic computed tomography (CT) has been identified as an effective tool for the diagnosis, yet the disease outbreak has placed tremendous pressure on radiologists for reading the exams and may potentially lead to fatigue-related mis-diagnosis. | 2020-08-21 |
| 32816835 | Focused cardiac ultrasound made the diagnosis. […] The case illustrates the importance of cardiac diagnostic imaging in patients with COVID-19 and elevated cardiac biomarkers. | 2020-08-21 |
| 32816921 | As we begin to recover from the pandemic, a cohesive international approach is needed, and guidance on how to resume endoscopy services safely to avoid unintended harm from diagnostic delays. | 2020-08-21 |
| 32816925 | This case highlights an atypical presentation of COVID-19 and the need for a high index of suspicion to allow early diagnosis and limit spread by isolation. | 2020-08-21 |
| 32817231 | The emergence of this new viral pathogen has raised unique diagnostic questions for which there have not always been straightforward answers. | 2020-08-21 |
| 32817233 | We prospectively compared health care worker-collected nasopharyngeal swabs (NPS) to self-collected anterior nasal swabs (ANS) and straight saliva for the diagnosis of coronavirus disease 2019 (COVID-19) in 354 patients. | 2020-08-21 |
| 32817769 | The current reference standard to make a definitive diagnosis of SARS-CoV-2 infection is the reverse transcription- polymerase chain reaction assay (rt-PCR). […] However, in the emergency setting CXR can be a useful diagnostic tool for monitoring the rapid progression of lung involvement in COVID-19, especially in patients admitted to intensive care units. […] Moreover, serial chest CT imaging with different time intervals is also effective in estimating the evolution of the disease from initial diagnosis to discharge from hospital. | 2020-08-21 |
| 32817820 | Tongue features should be referred for diagnosis and treatment of diseases in TCM. | 2020-08-21 |
| 32818035 | With the information from the app artificial intelligence techniques (data science) were applied in a virtual situation room. […] Users compatible with COVID-19 were prioritized and subjected to a rapid diagnostic test for anti-SARS-CoV-2 antibodies. […] Screening with the rapid diagnostic test would allow detection of sero-reactive individuals, for whom diagnostic confirmation would be carried out using molecular biology (PCR). […] Information from positive cases confirmed by PCR would be re-screened using artificial intelligence and spatial statistical techniques to identify geographical foci of infection. […] These foci could be actively searched for contacts with positive index cases and the diagnostic route would be followed again using the rapid diagnostic test and PCR. […] This model may be useful for countries in the region with weak or absent technological platforms for PCR diagnosis to maximize existing resources, estimate the epidemiological burden of COVID-19 (infection, morbidity, mortality and lethality) and implement containment, mitigation and control plans according to their needs. | 2020-08-21 |
| 32818132 | This review summarizes the existing status of current diagnostic methods, their possible limitations, and the advantages of biosensor-based diagnostics over the conventional ones for the detection of SARS-Cov-2. […] These could be effective tools for rapid, authentic, portable, and more promising diagnosis in the current pandemic that has affected the world economies and humanity. | 2020-08-21 |
| 32818515 | A diagnostic testing strategy that increases the maximum detection rate of asymptomatic infected individuals (followed by contact tracing and self-isolation of the detected cases) greatly reduces the burden of the pandemic in all four jurisdictions, particularly if also combined with a universal face mask use strategy. | 2020-08-21 |
| 32819219 | A total of 116 anaesthetic surgical procedures were carried out, of which 54 (46.5%) were oncological procedures, 18 (15.5%) were benign urological procedures, and 44 (38%) were diagnostic procedures. | 2020-08-22 |
| 32819917 | Pre-COVID, stakeholders described various preventive, diagnostic and treatment services, including well-used antenatal and immunisation programmes and some screening for hypertension, tuberculosis, HIV and vectorborne disease. | 2020-08-22 |
| 32819955 | All necessary data, including patient baseline information, diagnosis, follow-up conditions and the transfer records between the FC and ED, were collected and analysed. 6365 patients were screened in the FC, among whom 2912 patients were screened before 21 January 2020, while 3453 were screened afterward. | 2020-08-22 |
| 32819964 | The provision of acute medical care to LTC residents at their facility would probably require rapid access to outpatient diagnostic imaging, within-facility access to laboratory services and intravenous medication and virtual consultations with physicians. | 2020-08-22 |
| 32820626 | Cases of infection due to the measles virus are rapidly increasing, yet current diagnostic tools used to monitor for the virus rely on slow (>1 h) technologies. | 2020-08-22 |
| 32820725 | Paired swab (NPS and OPS) and gargle samples were taken within 72 h of their diagnosis. | 2020-08-22 |
| 32820807 | Data were collected on early (prescribed within 2 days of hospitalization) empiric antibacterial therapy and community-onset bacterial co-infections (positive culture or diagnostic test within 3 days). | 2020-08-22 |
| 32821259 | We analysed the effective reproductive number, underreporting of cases, burden of critical beds, case fatality ratio and number of diagnostic RT-PCR for SARS-CoV-2. […] However, at this time, the load of infected patients was high, with an important number of underreported cases; the diagnostic effort was still limited and heterogeneous across regions. | 2020-08-22 |
| 32821441 | Our provincial simulation program in the province of Alberta, Canada (population = 4.37 million; geographic area = 661,848 km2), has rapidly responded to this need by leading the intake, design, development, planning, and co-facilitation of over 400 acute care simulations across our province in both urban and rural Emergency Departments, Intensive Care Units, Operating Rooms, Labor and Delivery Units, Urgent Care Centers, Diagnostic Imaging and In-patient Units over a 5-week period to an estimated 30,000 learners of real frontline team members. | 2020-08-22 |
| 32821538 | Responses to the question of which clinical rotation worried them more were 29.9% endodontics, 25.1% oral and maxillofacial surgery, 16.3% prosthesis, 15.2% periodontology, 6.8% restorative dentistry, 3.9% oral diagnosis and radiology, 1.7% pedodontics, and 1.1% orthodontics, with a significant difference between the preclinical and clinical students. | 2020-08-22 |
| 32821612 | Similar symptoms, signs, and laboratory abnormalities between coronavirus disease 2019 (COVID-19) and pulmonary embolism (PE) creates a diagnostic challenge to every physician, and emerging data show an association between COVID-19, hypercoagulable state, and venous thromboembolism. […] Since EKG finding of SI QIII TIII pattern and right ventricular strain, and ECHO finding of right ventricular dysfunction are well described in PE but not in COVID-19, these bedside diagnostic tools can help identify COVID-19 patients with underlining PEs. | 2020-08-22 |
| 32821901 | To evaluate the presence of delirium in older patients admitted for a suspected diagnosis of COVID-19 and its impact on in-hospital mortality. 91 patients, aged 70-years and older, admitted to an acute geriatric ward in Northern Italy from March 8th to April 17th, 2020. […] Delirium was diagnosed by two geriatricians according to the Diagnostic and Statistical Manual of Mental Disorders V (DMS V) criteria. | 2020-08-22 |
| 32821907 | Accurate diagnostic strategies to rapidly identify SARS-CoV-2 positive individuals for management of patient care and protection of health care personnel are urgently needed. […] The predominant diagnostic test is viral RNA detection by RT-PCR from nasopharyngeal swabs specimens, however the results are not promptly obtainable in all patient care locations. | 2020-08-22 |
| 32822413 | In addition to the lack of COVID-19 diagnostic tests for the whole Spanish population, the current strategy is to identify the disease early to limit contagion in the community. | 2020-08-22 |
| 32822430 | Evidence-based characterization of the diagnostic and prognostic value of the hematological and immunological markers related to the epidemic of Coronavirus Disease 2019 (COVID-19) is critical to understand the clinical course of the infection and to assess in development and validation of biomarkers. | 2020-08-22 |
| 32822577 | Among currently available antibody tests, performance has been highly variable, with specificity around 90% or lower for rapid diagnostic tests and 95-99% for laboratory-based ELISA and chemiluminescent assays. | 2020-08-22 |
| 32822689 | Our iSCAN SARS-CoV-2 detection module, which exhibits the critical features of a robust molecular diagnostic device, should facilitate the effective management and control of COVID-19. | 2020-08-22 |
| 32822917 | Furthermore, policy briefs on the global initiatives for COVID-waste management including the applications of different disinfection techniques have also been discussed with some potential examples effectively applied to reduce both health and environmental risks. | 2020-08-22 |
| 32823131 | These non-validated specimen types, however, do have significant diagnostic value. | 2020-08-22 |
| 32823355 | The leading physicians reported numerous changes regarding occupancy in the hospital, patient composition, work flows and diagnostic as well as therapeutic measures. | 2020-08-22 |
| 32823852 | While lateral flow test formats can be utilized with whole blood and low sample volumes, their diagnostic characteristics are inferior to immunoassays based on chemiluminescence immunoassay (CLIA) or enzyme-linked immunosorbent assay (ELISA) technology. […] In receiver-operating characteristic curve analysis, all three assays displayed comparable diagnostic accuracy (area under the curve (AUC)) using corrected whole blood and serum (AUCs: 0.97 for ECLIA and IgG ELISA; 0.84 for IgA ELISA). | 2020-08-23 |
| 32823866 | Our antigen test allows for rapid, cost-effective, specific, ultrasensitive, and simultaneous multiple measurements of SARS-CoV-2, and has broad application for the diagnosis for COVID-19. | 2020-08-23 |
| 32824454 | Using a combined two-steps approach of virtual screening and molecular docking techniques, we have screened an in-house collection of small molecules, mainly composed of natural and nature-inspired compounds. | 2020-08-23 |
| 32824683 | Prompt RT-PCR is mandatory to confirm COVID-19 diagnosis. | 2020-08-23 |
| 32824767 | The Direct-One-Step-RT-qPCR (DIOS-RT-qPCR) assay detects severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in less than one hour while maintaining the high sensitivity and specificity required of diagnostic tools. | 2020-08-23 |
| 32824787 | Current diagnostic tools, reverse transcription PCR (RT-PCR) and real-time PCR (qPCR), have its pitfalls for quick pandemic containment such as the requirement for specialized professionals and instrumentation. […] Versatile electrochemical DNA/RNA sensors are a promising technological alternative for PCR based diagnosis. […] In this review, the authors discuss the most recent signal amplification strategies employed in the electrochemical DNA/RNA diagnosis of pathogens. | 2020-08-23 |
| 32824827 | However, the shortage of specific proprietary reagents or the lack of automated platforms have seriously hampered diagnostic throughput in many countries. […] Here, we provide a procedure for SARS-CoV-2 detection for diagnostic purposes from clinical samples in the setting of a basic research molecular biology lab. | 2020-08-23 |
| 32825060 | The purpose of this study was to use the Coronavirus Disease 2019 (COVID-19) Reporting and Data System (CO-RADS) to evaluate the chest computed tomography (CT) images of patients suspected of having COVID-19, and to investigate its diagnostic performance and interobserver agreement. […] The Dutch Radiological Society developed CO-RADS as a diagnostic indicator for assessing suspicion of lung involvement of COVID-19 on a scale of 1 (very low) to 5 (very high). | 2020-08-23 |
| 32825763 | In conclusion, our model could provide a simple, rapid, and cheap tool for prompt COVID-19 diagnostic triage in patients with CAP. | 2020-08-23 |
| 32825963 | Although pathological examination is not a feasible method of diagnosis, it can elucidate pathological changes, pathogenesis of the disease, and the cause of death in COVID-19 cases. | 2020-08-23 |
| 32826251 | The COVID-19 outbreak has had a high impact on diagnostic laboratory services recently. […] The current literature has focused on reviewing tests that are specifically related to the diagnosis of COVIDS-19 infection using either molecular testing or immunoassays detecting viral antigens or antibodies. | 2020-08-23 |
| 32826428 | We explore ways to reduce errors in laboratory diagnosis of severe acute respiratory syndrome-coronavirus 2 infection by considering preanalytic, analytic, and postanalytic sources. […] We included studies that compared diagnostic performance strategies without introducing bias due to use of an imperfect gold standard. […] Although sputum and bronchoalveolar lavage samples provide the highest diagnostic sensitivity for severe acute respiratory syndrome-coronavirus 2, nasopharyngeal, mid turbinate, and nasal specimens are suitable in most cases and require less use of personal protective equipment. | 2020-08-23 |
| 32826529 | Although SARS-CoV-2 is visualized on electron microscopy, there is an increasing demand for widely applicable techniques to visualize viral components within tissue specimens. | 2020-08-23 |
| 32826625 | Given that COVID-19 can severely impair lung function, regional anesthesia techniques avoiding phrenic nerve paralysis are relevant in the anesthetic management of suspected/confirmed COVID-19 patients requiring shoulder and clavicle surgical procedures. […] The objective of this review is to provide an overview of recently published studies examining ultrasound-guided diaphragm-sparing regional anesthesia techniques for the brachial plexus (BP) to favor their preferent use in patients at risk of respiratory function compromise. […] In the last 18 months, study findings on various diaphragm-sparing regional anesthesia techniques have demonstrated comparable block analgesic effectivity with a variable extent of phrenic nerve paralysis. […] Existing diaphragm-sparing brachial plexus regional anesthesia techniques used for shoulder and clavicle surgery may help minimize pulmonary complications by preserving lung function, especially in patients prone to respiratory compromise. | 2020-08-23 |
| 32826719 | The first positive case was identified with a point-of-care diagnostic system on site. | 2020-08-23 |
| 32826846 | Healthcare workers must utilize appropriate personal protective equipment (PPE) and infection control prevention techniques given the high risk of transmission and potential morbidity associated with COVID-19. […] CONCLUSIONS We present the first known case report highlighting use of telemedicine to diagnosis COVID-19 in a patient present in the ED. […] Use of telemedicine affords multiple benefits in the effective diagnosis, evaluation, and potential prevention of spread of COVID-19. | 2020-08-23 |
| 32827009 | The lack of knowledge among health care professionals leads to diagnostic delays, further spread of disease, and poor infection control practices. | 2020-08-23 |
| 32827394 | Objectives Clinical laboratories plays a key role in screening, diagnosis and containment of the Coronavirus 2019 infection epidemic. […] The etiological diagnosis presupposes the isolation of virus genetic material in the patient’s biological sample but laboratory diagnostics also make use of searching possibility for IgG, IgM classes antibodies. […] Results Thirty two days after performing the first diagnostic swab, 39 of 43 patients (90%) had IgG higher than the cut off value. | 2020-08-23 |
| 32827582 | Moreover, because the signs and symptoms of COVID-19 are easily misattributed to the sequelae of cancer itself, such as pulmonary embolism, or its treatment, such as nausea and diarrhea, diagnosis may be delayed or missed. […] This review summarizes the current understanding of the transmission, clinical presentation, diagnosis and differential diagnosis, pathogenesis, rationale to treat the cancer or not, treatment and prevention of COVID-19 with an emphasis on implications in cancer. | 2020-08-23 |
| 32827898 | ELISA and qualitative rapid chromatographic immunoassays can be used for the diagnosis of RT-PCR-negative patients. | 2020-08-23 |
| 32828135 | One hundred ninety-four patients with confirmed diagnosis of COVID-19 were included in the study after signing informed consent. | 2020-08-24 |
| 32828189 | Clinicians can encounter sex and gender disparities in diagnostic and therapeutic responses. […] We aim to guide clinicians and researchers to consider sex and gender in their approach to diagnosis, prevention, and treatment of diseases as a necessary and fundamental step towards precision medicine, which will benefit men’s and women’s health. | 2020-08-24 |
| 32828577 | In COVID-19 patients, lung ultrasound is a promising diagnostic tool in diagnosing patients with refractory pneumonia. | 2020-08-24 |
| 32828701 | This reassuring study concerning the risk of COVID-19 in patients with CF illustrates the difficulty to distinguish COVID-19 symptoms from respiratory exacerbations and the need of generalized molecular testing to make a precise diagnosis. | 2020-08-24 |
| 32828735 | Clinical prediction scores support the assessment of patients in the emergency setting to determine the need for further diagnostic and therapeutic steps. […] Descriptive statistics, Student’s t-test, ANOVA and Scheffe’s post-hoc analysis confirmed the diagnostic power of the score. | 2020-08-24 |
| 32828791 | Eligibility criteria for CCP donors includes documentation of evidence of COVID-19 either by viral RNA detection at the time of illness or positive SARS-CoV-2 IgG after recovery if diagnostic testing for COVID-19 was not performed at the time of illness. […] In addition to analysis of CCP, analysis of SARS-CoV-2 IgG provides information for possible past exposure and may support diagnosis when SARS-CoV-2 PCR is negative and clinical suspicion for COVID-19 is high. | 2020-08-24 |
| 32829053 | Early, rapid and accurate diagnosis is of great significance for curtailing the spread of SARS-CoV-2. […] There are currently several diagnostic techniques (e.g. viral culture and nucleic acid amplification test) being used to detect the virus. […] This study reviewed all types and characteristics of the currently available laboratory diagnostic assays for detecting SARS-CoV-2 infection and summarized the selection strategies of testing and sampling sites at different disease stages to improve the diagnostic accuracy of Coronavirus Disease 2019 (COVID-19). | 2020-08-24 |
| 32829312 | Background Historically, the lactate dehydrogenase (LDH) measurement was introduced into Laboratory Medicine as component (together with creatine kinase (CK) and aspartate aminotransferase) of the classical enzyme triad employed for the diagnosis of myocardial infarction, which was subsequently replaced by CK-MB, and more recently by cardiac troponins. | 2020-08-24 |
| 32829511 | We searched studies trough MEDLINE/EMBASE database, including patient with IMID, undergoing immunosuppressive treatment with a positive diagnosis for SARS-CoV 2. | 2020-08-24 |
| 32829730 | Step 1: 15 first-line medical health workers were trained to use six different relaxation techniques and reported the two most feasible techniques while wearing medical protective equipment. […] Step 2: the most two feasible relaxation techniques revealed by step 1 were quantitatively tested in a sample of 65 medical health workers in terms of efficacy, no space limitation, no time limitation, no body position requirement, no environment limitation to be done, easiness to learn, simplicity, convenience, practicality, and acceptance. […] Kegel exercise and autogenic relaxation were the most feasible techniques according to step 1. | 2020-08-25 |
| 32829742 | This decline of HIV diagnosis is caused by missed diagnoses of individuals infected before the establishment of such measures and to the reduction of high-risk sexual behaviours during the COVID-19 pandemic. | 2020-08-25 |
| 32829745 | The primary endpoint following the 30-day study period is the difference in the number of SARS-CoV-2-infected individuals between the two study groups as assessed by a positive nasopharyngeal swap, a positive antibody test or a hospital-based diagnosis of SARS-CoV-2 infection. | 2020-08-25 |
| 32829971 | To control for confounding variables, we performed a multivariate analysis to identify the effect of hip fracture diagnosis on costs. | 2020-08-25 |
| 32830031 | The aim of this study was to compare the findings found in thorax computed tomography (CT), which is increasingly used in the diagnosis of the important public health problem of coronavirus disease (COVID-19), and the findings of magnetic resonance imaging (MRI) as an important diagnostic alternative. […] Although thorax CT is widely used in the imaging of COVID-19 infection, due to its advantages, MRI can also be used as an alternative diagnostic tool. | 2020-08-25 |
| 32831151 | The patients, who are aged from 18 to 75 years old, with a confirmed or suspected diagnosis of severe or critical COVID-19, will be consecutively recruited in the study, according to the guideline on diagnosis and treatment of COVID-19 (the 7th version) issued by National Health Commission of the People’s Republic of China. | 2020-08-25 |
| 32831319 | According to published reports, neurological disorders are not uncommon in COVID-19 and can sometimes represent the first manifestation of the disease; therefore, neurologists should consider this diagnostic possibility in their daily practice. | 2020-08-25 |
| 32831342 | Between March 10 and May 15, 2020, the COVID Unit was created in the corresponding regional hospital, and an independent circuit was established for the diagnosis and management of patients with suspected or confirmed COVID-19; social health centers were monitored with PCR testing. | 2020-08-25 |
| 32831935 | Most of the published papers have addressed clinical presentation, diagnostic tests, mitigation measures, and hospital preparedness. | 2020-08-25 |
| 32831936 | The aim of the present work was to understand the underlying disease profile and dynamics that could provide relevant inputs and insight into pathophysiology and prevent further spread and evolve management strategies of COVID-19 patients from data-driven techniques. | 2020-08-25 |
| 32831937 | Severe acute respiratory syndrome-coronovirus-2 is a global public health problem, in which early diagnosis is required to prevent the spread of infection. […] In this study, we aimed to reveal the diagnostic value of chest computed tomography (CT) imaging with respect to symptom duration. […] Chest CT imaging is a quite valuable tool in patients with longer than 2 days’ duration of symptoms, in whom clinical and epidemiological data support the diagnosis of COVID-19 infection. […] We suggest that the diagnosis of COVID-19 pneumonia should be made with chest CT imaging when rtRT-PCR test cannot be performed or gives a negative result, which is important for public health and to prevent the spread of infection. | 2020-08-25 |
| 32832047 | The experimental observations suggest the potential applicability of such Deep CNN based approach in real diagnostic scenarios, which could be of very high utility in terms of achieving fast testing for COVID19. | 2020-08-25 |
| 32832591 | Data including diagnosis, operation/procedural interventions, and length of stay were analysed. | 2020-08-25 |
| 32832739 | Sepsis is a commonly encountered diagnosis affecting nearly 1.7 million adults in the USA annually. | 2020-08-25 |
| 32833283 | The aim of this work was to study characteristics, cardiovascular outcomes and mortality in patients with confirmed COVID-19 infection and a prior diagnosis of heart failure (HF). […] Moreover, patients with a history of CHF are prone to developing acute decompensation after a COVID-19 diagnosis. | 2020-08-25 |
| 32833384 | However, physical distancing requirements during a global pandemic have resulted in cancellation and/or postponement of “in-person” educational sessions, ultrasound conferences, and clinical diagnostic and interventional ultrasound cases that enhance ultrasound training. | 2020-08-25 |
| 32833506 | It is essential for biobanks to collect COVID-19 specimens along with corresponding clinical and demographic data from COVID-19 diagnostic testing. | 2020-08-25 |
| 32833548 | Previous outbreaks of coronaviruses and other viruses have suggested the importance of diagnostic technologies in fighting viral outbreaks. […] Nucleic acid detection techniques are the gold standard for detecting SARS-CoV-2. […] Nevertheless, the availability, cost, and performance of existing viral diagnostic technologies limit their practicality, and novel approaches are required for improving our readiness for global pandemics. […] Here, we review the principles and limitations of major viral diagnostic technologies and highlight recent advances of molecular assays for COVID-19. […] The prospects of viral diagnostic technologies for combating future pandemic threats are presented. | 2020-08-25 |
| 32833573 | Realizing the need for current information, this summary provides a focused summary of pertinent clinical diagnostic information about neurological involvement of SARS-CoV-2 virus and clinical presentation of COVID-19, especially in relationship to patients with seizures and epilepsy. | 2020-08-25 |
| 32833671 | We compared the clinicopathological characteristic of patients stratified according to age and underlying diseases, as well as assessed the detection rates of different diagnostic methods. | 2020-08-25 |
| 32833771 | In this article, we explore the diagnostic modalities for COVID-19 based on the available information to date. | 2020-08-25 |
| 32833954 | The present report highlights a patient with no precipitating risk factors for pancreatitis who presented with recurring acute pancreatitis following the diagnosis of SARS-CoV-2 infection. […] After ruling out the possible causes of acute pancreatitis, a diagnosis of idiopathic acute pancreatitis was made. | 2020-08-25 |
| 32834137 | Accordingly, we develop a model which we analyse using the structural equation modelling and neural network techniques with data collected from young adults in Bangladesh (N = 433). | 2020-08-25 |
| 32834176 | Crime data representing residential burglary, commercial burglary, theft of vehicle, theft from vehicle, theft, violence, and mischief are analysed at the city level using interrupted time series techniques. | 2020-08-25 |
| 32834193 | Respecting contra-indications and judicial use of safety techniques and norms are essential. | 2020-08-25 |
| 32834243 | Infectious diseases, such as the most recent case of coronavirus disease 2019, have brought the prospect of point-of-care (POC) diagnostic tests into the spotlight. […] We conclude our review with a discussion of the latest findings on nucleic acid-based diagnosis. | 2020-08-25 |
| 32834259 | In the present investigation, we characterized the SARS-CoV-2 spike glycoprotein by immunoinformatics techniques to put forward potential B and T cell epitopes, followed by the use of epitopes in construction of a multi-epitope peptide vaccine construct (MEPVC). | 2020-08-25 |
| 32834269 | Conditional formatting techniques, time-series trends plotting method, spatial inverse distance weighted (IDW) interpolation mapping techniques have been employed to show pre and post lockdown mobility trends due to COVID-19 i.e. to fulfill the objective. | 2020-08-25 |
| 32834308 | We describe the management of the different pelvic floor dysfunctions during COVID-19 pandemic and a proposal to organize the urogynaecological services to diagnose (visits and diagnostic investigations) and to treat (conservative, pharmacological or surgery) in the interpandemic period and in the future. | 2020-08-25 |
| 32834328 | We apply the supervised learning techniques to identify and train NP-Net-SIR model which turns out robust under poor data quality condition. | 2020-08-25 |
| 32834517 | Finally, we applied the hybrid HFACS-BN model to analyze the COVID-19 outbreak in China by virtue of its efficacy in probability prediction and diagnosis of key risk factors, and thus to test the feasibility of the model itself. | 2020-08-25 |
| 32834553 | Extensive experiments have been done considering the proposed detection strategy as well as recent competitive techniques on the chest CT images. […] Experimental results have shown that the proposed detection strategy outperforms recent techniques as it introduces the maximum accuracy rate. | 2020-08-25 |
| 32834556 | To help make rapid decisions on treatment and isolation needs, it would be useful to determine which features presented by suspected infection cases are the best predictors of a positive diagnosis. […] This can be done by analyzing patient characteristics, case trajectory, comorbidities, symptoms, diagnosis, and outcomes. […] While 54.4% of people examined did not develop any symptoms that could be used for diagnosis, our work indicates that for the remainder, our predictive model could significantly improve the prediction of COVID-19 status, including at early stages of infection. | 2020-08-25 |
| 32834577 | To do this, we employ a simple epidemiological model and analyse this system using modelling and dynamical systems techniques. | 2020-08-25 |
| 32834580 | The model results revealed that 1) the transmission, infection and recovery dynamics follow the integral-order SEIR model with significant spatiotemporal variations in the recovery rate, likely due to the continuous improvement of screening techniques and public hospital systems, as well as full city lockdowns in China, and 2) the evolution of number of deaths follows the time FDE, likely due to the time memory in the death toll. | 2020-08-25 |
| 32834586 | Our main contribution is that in a scenario of continuously evolving training data, unlike typical deep learning techniques, this non-intrusive algorithm eliminates the need to retrain or rebuild the model from scratch every time a new training data set is received. | 2020-08-25 |
| 32834587 | In this manuscript, system modeling and identification techniques are applied in developing a prognostic yet deterministic model to forecast the spread of COVID-19 in India. | 2020-08-25 |
| 32834591 | All AI techniques are evaluated in the task of time-series forecasting with one, three, and six-days-ahead the cumulative COVID-19 cases in five Brazilian and American states, with a high number of cases up to April 28th, 2020. | 2020-08-25 |
| 32834601 | The purpose of this study is to give tentative predictions of the epidemic peak for Russia, Brazil, India and Bangladesh which could become the next COVID-19 hotspots in no time by using a newly developed algorithm based on well-known Trust-region-reflective (TRR) algorithm, which is one of the robust real-time optimization techniques. | 2020-08-25 |
| 32834618 | Furthermore, we carried out the global sensitivity analysis of the most crucial parameter known as the basic reproduction number using the Latin Hypercube Sampling (LHS) and the partial rank correlation coefficient (PRCC) techniques. | 2020-08-25 |
| 32834623 | In this work, we analyze the sources of error in typically reported epidemiological variables and usual tests used for diagnosis, and their impact on our understanding of COVID-19 spreading dynamics. […] We address the existence of different delays in the report of new cases, induced by the incubation time of the virus and testing-diagnosis time gaps, and other error sources related to the sensitivity/specificity of the tests used to diagnose COVID-19. | 2020-08-25 |
| 32834625 | The proposed model is simple but potentially useful in estimating the unidentified infected population to monitor the effectiveness of interventions and to prepare the quantity of protective masks or COVID-19 diagnostic kit to supply, hospital beds, medical staffs, and so on. | 2020-08-25 |
| 32834627 | Real-time reverse transcription-polymerase chain reaction (RT-PCR) test has been described by the World Health Organization (WHO) as the standard test method for the diagnosis of the disease. […] However, considering that the results of this test are obtained between a few hours and two days, it is very important to apply another diagnostic method as an alternative to this test. […] The fact that RT-PCR test kits are limited in number, the test results are obtained in a long time, and the high probability of healthcare personnel becoming infected with the disease during the test, necessitates the use of other diagnostic methods as an alternative to these test kits. | 2020-08-25 |
| 32834634 | The similarity of COVID-19 disease with other lung infections makes the diagnosis difficult. […] In addition, the high spreading rate of COVID-19 increased the need for a fast system for the diagnosis of cases. […] It is thought that the proposed method may help physicians to diagnose COVID-19 disease and increase the diagnostic performance. | 2020-08-25 |
| 32834641 | Driven by the desire to develop a computer-aided system for the rapid diagnosis of COVID-19 to assist radiologists and clinicians to combat with this pandemic, we retrospectively collected 206 patients with positive reverse-transcription polymerase chain reaction (RT-PCR) for COVID-19 and their 416 chest computed tomography (CT) scans with abnormal findings from two hospitals, 412 non-COVID-19 pneumonia and their 412 chest CT scans with clear sign of pneumonia are also retrospectively selected from participating hospitals. […] Experimental results show that the proposed AI has promising diagnostic performance in the detection of COVID-19 and differentiating it from other common pneumonia under limited number of training data, which has great potential to assist radiologists and physicians in performing a quick diagnosis and mitigate the heavy workload of them especially when the health system is overloaded. | 2020-08-25 |
| 32834643 | The objective of this paper is to extract the activity and trends of coronavirus related research articles using machine learning approaches to help the research community for future exploration concerning COVID-19 prevention and treatment techniques. […] Clustering techniques are used to create the different clusters of available articles, and later the task assignment is performed using parallel one-class support vector machines (OCSVMs). | 2020-08-25 |
| 32834651 | The international community tries to find, apply, or design novel methods for diagnosis and treatment of COVID-19 patients as soon as possible. […] Currently, a reliable method for the diagnosis of infected patients is a reverse transcription-polymerase chain reaction. […] In this paper, we used three deep learning-based methods for the detection and diagnosis of COVID-19 patients with the use of X-Ray images of lungs. […] For the diagnosis of the disease, we presented two algorithms include deep neural network (DNN) on the fractal feature of images and convolutional neural network (CNN) methods with the use of the lung images, directly. | 2020-08-25 |
| 32834658 | Yet, the diagnosis of virus spread in humans has proven complexity. […] The image diagnosis tool utilizes decision tree classifier for finding novel corona virus infected person. | 2020-08-25 |
| 32834785 | ASPs can also play a critical role in the management of potential drug shortages, developing local treatment guidelines, optimizing the use of antibiotics, and in the diagnostic stewardship of COVID-19 testing, among other roles. | 2020-08-25 |
| 32834902 | This article aims at presenting an up-to-date review on the pathogenesis, diagnosis and complications of COVID-19 infection. | 2020-08-25 |
| 32834986 | Literature review also proposes changes to the diagnostic work up in COVID-19 patients, such as earlier screening for pulmonary embolism in critically ill. | 2020-08-25 |
| 32834988 | Cardiac ultrasound, electrocardiogram and clinical findings suggested a diagnosis of cardiogenic obstructive shock due to acute pulmonary embolism, successfully treated with thrombolysis. […] A CT angiography confirmed the pulmonary embolism (EP) diagnosis and showed bilateral pneumonia, caused by SARS-CoV-2 infection. | 2020-08-25 |
| 32835001 | COVID-19 has become a substantial lethal disease worldwide, and early diagnosis is a significant concern for this virus. […] Furthermore, the recent develop biosensor leading to others diagnosis approach but being invasive are painful and time taking. […] This review commences with the recent develop biosensor for Covid-19 detection and listing down the available biomarkers with their secretion range comparison of normal to COVID-19 patients through clinical analysis in china and concludes with the future approach for the diagnosis. | 2020-08-25 |
| 32835017 | The diagnosis of SARS-CoV-2 encephalitis is difficult as CSF analysis may be normal. | 2020-08-25 |
| 32835023 | We describe a patient in Tanzania who experienced severe headache for seven days before the onset of other symptoms of COVID-19 that led to her isolation, diagnosis, and treatment. | 2020-08-25 |
| 32835036 | In a big effort to cope with this outbreak, two Uruguayan institutions, Institut Pasteur de Montevideo and Universidad de la República, have developed and implemented a diagnosis pipeline based on qRT-PCR using entirely local resources. […] In this context, we performed comparative quantitative proteomic analysis from oro- and naso-pharyngeal swabs used for diagnosis. […] We expect that this data can contribute to the future development of mass spectrometry based approaches for COVID-19 diagnosis. | 2020-08-25 |
| 32835037 | Of these 644 patients, 640 cases were eventually confirmed with a diagnosis of COVID-19. […] Among the 211 anesthesiologists who performed intubation, 10 of them had a confirmed diagnosis of COVID-19 afterwards. | 2020-08-25 |
| 32835055 | Local scientists and developers have also developed rapid diagnostic test kits, ventilators, and solar-powered handwashing machines. | 2020-08-25 |
| 32835074 | Genomic techniques such as next-generation sequencing and microarrays have facilitated the identification and classification of molecular signatures inherent in cells upon viral infection, for possible therapeutic targets. | 2020-08-25 |
| 32835077 | Timely diagnosis of lung disease is essential. […] Different forms of existing deep learning techniques including convolutional neural network (CNN), vanilla neural network, visual geometry group based neural network (VGG), and capsule network are applied for lung disease prediction. | 2020-08-25 |
| 32835080 | It is, therefore, crucial to expedite the process of early detection and diagnosis of the disease across the world. | 2020-08-25 |
| 32835082 | As there are no distinctive COVID-19 positive case detection tools available, the need for supporting diagnostic tools has increased. […] Recent findings from X-Ray imaging techniques suggest that such images contain relevant information about the SARS-CoV-2 virus. […] Application of Deep Neural Network (DNN) techniques coupled with radiological imaging can be helpful in the accurate identification of this disease, and can also be supportive in overcoming the issue of a shortage of trained physicians in remote communities. | 2020-08-25 |
| 32835084 | An automatic disease detection framework assists doctors in the diagnosis of disease and provides exact, consistent, and fast results and reduces the death rate. […] Therefore, an automated detection system, as the fastest diagnostic option, should be implemented to impede COVID-19 from spreading. | 2020-08-25 |
| 32835086 | Diagnostic tests, laboratory examinations, clinical findings and computed thorax tomography imaging of the patients were evaluated. | 2020-08-25 |
| 32835131 | Skin biopsy favored a diagnosis of toxic shock syndrome. | 2020-08-25 |
| 32835145 | The fitted model fitted well to the dataset and was free of any violation based on the diagnostic checks conducted. | 2020-08-25 |
| 32835154 | We review the current medical and manufacturing response to COVID-19, including advances in instrumentation, sensing, use of lasers, fumigation chambers and development of novel tools such as lab-on-the-chip using combinatorial additive and subtractive manufacturing techniques and use of molecular modelling and molecular docking in drug and vaccine discovery. | 2020-08-25 |
| 32835155 | Biosensors are emerging as efficient (sensitive and selective) and affordable analytical diagnostic tools for early-stage disease detection, as required for personalized health wellness management. | 2020-08-25 |
| 32835276 | This may have important diagnostic, monitoring, and pathogenic implications. | 2020-08-25 |
| 32835314 | In this study, several computational techniques are implemented to analyze the survival characteristics of 1,182 patients. | 2020-08-25 |
| 32835346 | Since the COVID-19 outbreak, diagnostic imaging has been providing valuable radiological support for disease diagnosis and prognosis prediction. […] A number of relevant professionals and experts reached a consensus, which clarifies the detailed implementing rules with respective to infection control and protection of the radiation workers, disinfection of diagnostic radiology equipment and workplace, and radiological protection. | 2020-08-25 |
| 32835351 | Due to the critical significance and increasing prevalence of the disease, several national and international societies have recently updated their guidelines for the diagnosis and treatment of HTN. […] While a partial emphasis is placed on the management of HTN in the midst of COVID-19, this review will summarize current concepts and emerging data from the listed HTN guidelines on the diagnosis, monitoring, management, and evidence-based treatments in adults. | 2020-08-25 |
| 32835681 | Using novel panel estimation techniques, our results find strong evidence of causation between meteorological factors and COVID-19 outcomes. | 2020-08-25 |
| 32835738 | The growing demand for commercial kits used for automated extraction of SARS-CoV-2 RNA, a key step before rRT-PCR diagnosis, could cause a shortage of stocks that hinders the rapid processing of samples. […] Consequently, this simple and inexpensive method is a suitable procedure for laboratory diagnosis of SARS-CoV-2 infection. | 2020-08-25 |
| 32835787 | To determine the diagnostic yield of repeat testing for SARS-CoV-2. […] We found a low diagnostic yield of repeat testing for SARS-CoV-2 in our health system. | 2020-08-25 |
| 32835900 | The collected data included recent contact with a patient with COVID-19 diagnosis or a subject with respiratory symptoms and the developing of COVID-19 symptoms or a confirmed diagnosis. 15 out of 275 patients reported symptoms suggestive for COVID-19 infection, only one of them with PCR-confirmed diagnosis. […] Using a multivariable logistic regression model, the only factor associated with being in the COVID-suspect group was the report of a recent contact with a patient with a COVID-19 diagnosis. | 2020-08-25 |
| 32835961 | Investments in circular technologies like feedstock recycling, improving the infrastructure and environmental viability of existing techniques could be the key to dealing with the plastic waste fluxes during such a crisis. | 2020-08-25 |
| 32836042 | Our ENT guidelines regarding personal protection equipment and multiple simultaneous diagnostic procedures have proved to be an essential instrument for the management of patients with both known and unknown COVID-19 status. | 2020-08-25 |
| 32836303 | These intricacies of computer techniques in the area of psychotherapy, techniques with which we had some questioning, became established as quickly as the virus: the task of clinicians and researchers to measure the issues and the consequences. | 2020-08-25 |
| 32836376 | Consequently, we introduce major premises and techniques borrowed from Accelerated Experiential Dynamic Psychotherapy as they may apply to teletherapy. | 2020-08-25 |
| 32836378 | Finally, we illustrate with clinical vignettes how the developmental levels of mentalizing-attention control, emotion regulation, and explicit mentalizing-can inform the structure, techniques and interventions in teletherapy with children and parents. | 2020-08-25 |
| 32836379 | In tandem with these techniques, behavioral activation and coping strategies including relaxation, distress tolerance, and acceptance promote engaging in positive and adaptive activities. | 2020-08-25 |
| 32836490 | Administrative routines and established management techniques have dissolved amid emergency actions and management by the state of exception. | 2020-08-25 |
| 32836613 | The main objective of this work is to propose a high speed, accurate and highly sensitive CT scan approach for diagnosis of COVID19. | 2020-08-25 |
| 32836666 | Of the total population, 447 979 inhabitants, 965 patients (0.22%) were diagnosed with COVID-19 infection, and 210 (21.8%) were under ACEI or ARB treatment at the time of diagnosis. | 2020-08-25 |
| 32836696 | In this paper, we establish a mathematical model for COVID-19 transmission involving the interactive effect of various factors for the infected people, including imported cases, isolating rate, diagnostic rate, recovery rate and also the mortality rate. […] Under the assumption that the random incubation period, the cure period and the diagnosis period are subject to the Weibull distribution, the quantity of daily existing infected people is finally governed by a linear integral-differential equation with convolution kernel. | 2020-08-25 |
| 32836805 | Due to the strong infectivity of COVID-19, it spread all over the world in about three months and thus has been studied from different aspects including its source of infection, pathological characteristics, diagnostic technology and treatment. | 2020-08-25 |
| 32836817 | Then, the proposed fractional model can also predict the peak of diagnosis. | 2020-08-25 |
| 32836849 | This relationship between Covid-19 and air pollution withstands a number of sensitivity and robustness exercises including instrumenting pollution to mitigate potential endogeneity in the measurement of pollution and modelling spatial spillovers using spatial econometric techniques. | 2020-08-25 |
| 32836898 | In all 8 fatal cases, the autopsy diagnosis was death due to COVID-19. | 2020-08-25 |
| 32836916 | As the early prediction can reduce the spread of the virus, it is highly desirable to have intelligent prediction and diagnosis tools. […] In this paper, a state-of-the-art analysis of the ongoing machine learning (ML) and deep learning (DL) methods in the diagnosis and prediction of COVID-19 has been done. | 2020-08-25 |
| 32837036 | The diagnosis of COVID-19 should be based on imaging findings along with epidemiological history and nucleic acid detection. | 2020-08-25 |
| 32837105 | The response-rates and the volume of patients requiring physical visits were measured for different diagnosis-based groups. | 2020-08-25 |
| 32837214 | The diagnosis of pulmonary embolism could be difficult in this setting. | 2020-08-25 |
| 32837253 | We propose secure and efficient techniques for private processing of location updates that complement the use of PBC and lead to significant gains in performance by reducing the amount of required pairing operations. […] Extensive experimental results show that the proposed techniques significantly improve performance compared to the baseline, and reduce the searchable encryption overhead to a level that is practical in a computing environment with reasonable resources, such as the cloud. | 2020-08-25 |
| 32837281 | Datasets were analysed through a set of statistical techniques including classical test theory, principal component analysis, hierarchical cluster analysis, Pearson’s correlation matrix and linear regression analysis. | 2020-08-25 |
| 32837297 | However, in practices such as traditional Japanese (Kampo) medicine, where color is used as an important examination factor, an accurate diagnosis cannot be made without adequate color reproduction. | 2020-08-25 |
| 32837305 | Close cooperation with other specialist areas such as hygiene, infectiology or virology is also necessary in order to implement appropriate treatment concepts before, during and after the diagnosis is completed. | 2020-08-25 |
| 32837366 | The stock market information of the top 32 coronavirus affected economies (as of 31st March 2020) was sampled for ex-ante and ex-post COVID-19 outbreak analysis using the Detrended Moving Cross-Correlation Analysis (DMCA) and Detrended Cross-Correlation Analysis (DCCA) techniques. | 2020-08-25 |
| 32837398 | APRNs must remain current on best practices for treatment and diagnosis of COVID-19 while being cognizant of changes to their scope of practice. | 2020-08-25 |
| 32837409 | We conducted a retrospective chart review of patients admitted with a diagnosis of COVID-19 who received either telerehabilitation only or a combination of telerehabilitation and in-person rehabilitation. […] We analyzed data of inpatients who received telerehabilitation only, which included patient education, therapeutic exercises, and breathing techniques. | 2020-08-25 |
| 32837415 | We conducted a retrospective observational cohort study of all patients admitted between April 1 and April 21, 2020, who had a diagnosis of COVID-19. | 2020-08-25 |
| 32837502 | In particular, useful models can be derived from process integration techniques that deal with tight resource constraints. | 2020-08-25 |
| 32837505 | This study analysed the implications of the genetic diversity and mutations in SARS-CoV-2 on its virulence diversity and investigated how these factors could affect the successful development and application of antiviral chemotherapy and serodiagnostic test kits, and vaccination. | 2020-08-25 |
| 32837510 | However, the requirement of skilled operators, expensive instrumentation, and biosafety laboratories has hindered the use of NAAT for screening and diagnosis of suspected patients. […] This enclosed and automated microfluidic system efficiently avoids viral contamination of aerosol, and can be readily adapted for virus detection outside the diagnostic laboratory. | 2020-08-25 |
| 32837527 | “Appropriate” diagnostic testing in response to the SARS-CoV-2 outbreak should be urgently considered. […] This perspective review gives particular attention to the potential diagnostic testing of the virus in semen and seminal fluids due to its high levels of angiotensin converting enzyme 2 (ACE2) precursor. | 2020-08-25 |
| 32837582 | The purpose of this review is to summarize emerging technologies being implemented in the study, diagnosis, and treatment of COVID-19. | 2020-08-25 |
| 32837587 | The emergence of a novel coronavirus, SARS-CoV-2, has highlighted the need for rapid, accurate, and point-of-care diagnostic testing. […] This review focuses on the development of lab-on-chip biosensing platforms for diagnosis of COVID-19 infection. […] We focus on rapid, point-of-care technologies that can be deployed at scale, as such devices could be promising alternatives to the current gold standard of reverse transcription-polymerase chain reaction (RT-PCR) diagnostic testing. | 2020-08-25 |
| 32837668 | A reduction in the pacemaker implant of 73% (95% CI: 33-113; P < .001) was observed during the COVID-19 pandemic period, and a reduction of 78% of patients with the diagnosis of complete or high-grade atrioventricular block and a reduction in the de-novo pacemaker implant was observed, regardless of the etiology. | 2020-08-25 |
| 32837670 | Since the widespread of acute respiratory syndrome infection caused by Coronavirus-19 unenhanced computed tomography (CT) was considered an useful imaging tool commonly used in early diagnosis and monitoring of patients with complicated COVID-19 pneumonia. | 2020-08-25 |
| 32837672 | Our case highlights the importance of considering SARS-Cov-2 infection in the differential diagnosis for patients with unexplained central nervous system dysfunction and cerebral edema to prevent delayed diagnosis and render rapid treatment. | 2020-08-25 |
| 32837679 | To resolve this problem, radiological imaging techniques such as chest X-rays and computed tomography (CT) are used to detect and diagnose COVID-19. | 2020-08-25 |
| 32837715 | I suggest several models of remote substitutions for traditional field teaching of identification, field techniques, data collection, and study design in the context of the results of this survey. | 2020-08-25 |
| 32837726 | Appropriate diagnosis and isolation of the patients help reduce further transmission. | 2020-08-25 |
| 32837738 | To curb the spread of the COVID-19 (coronavirus disease 2019) pandemic, the world needs diagnostic systems capable of rapid detection and quantification of the novel coronavirus (SARS-CoV-2). […] However, the diagnostic technologies have specific limitations and reported several false-positive and false-negative cases, especially during the early stages of infection. […] The literature survey and performance-based analysis of the commercial and pre-commercial molecular diagnostics address several questions and issues related to the limitations of current technologies and highlight future research and development challenges to enable timely, rapid, low-cost, and accurate diagnosis of emerging infectious diseases. | 2020-08-25 |
| 32837739 | Competence in proper donning and doffing of PPE accompanied by hand washing techniques was of utmost importance for infection control. | 2020-08-25 |
| 32837749 | This study aimed to establish an early screening model to distinguish COVID-19 pneumonia from IAVP and healthy cases through pulmonary CT images using deep learning techniques. […] The deep learning models established in this study were effective for the early screening of COVID-19 patients and were demonstrated to be a promising supplementary diagnostic method for frontline clinical doctors. | 2020-08-25 |
| 32837758 | In this article, we drafted the recommendations for diagnosis and treatment of emergency surgeries in otorhinolaryngology, head and neck surgery in the epidemic area of novel coronavirus pneumonia based on “Novel Coronavirus Pneumonia Diagnosis and Treatment Plan (Provisional; 7th Edition Revisions)”and WHO guidelines, combined with the experience of emergency surgeries in the Department of Otorhinolaryngology, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, which is at the center outbreak area of the SARS-CoV-2 pneumonia (COVID-19) in China, to improve the success rate of treatment for otorhinolaryngology, head and neck surgery emergency surgeries and to reduce the SARS-CoV-2 infection rate in the perioperative period. | 2020-08-25 |
| 32837759 | In the realm of otolaryngology, telemedicine has been used in the past during disasters with other studies demonstrating high diagnostic concordance with inpatient visits. | 2020-08-25 |
| 32837801 | The purpose of the review is to describe the Brazilian Telemedicine University Network RUTE concerning the Special Interest Group of Children and Adolescents, the new SIG-COVID19-BR activities for continuing medical education, and to update relevant information regarding diagnosis and treatment, using digital technologies. | 2020-08-25 |
| 32837806 | Assessment on practices towards COVID-19 included questions on techniques while imaging against COVID-19 suspected patients. […] Most of the respondents (48.5%) incorrectly considered X-ray as the reliable method of diagnosis for suspected COVID-19 patients. | 2020-08-25 |
| 32837839 | It is now time to end prejudice and adopt in this fight against Covid-19 alternative therapeutic techniques and practices that historically have proven effective in corresponding situations. | 2020-08-25 |
| 32837848 | Thus, in this work the recent literature surrounding the biology, clinical manifestations, and immunology of SARS-CoV-2 is summarized, with the aim of aiding prevention, diagnosis, and treatment for SARS-CoV-2 infection. | 2020-08-25 |
| 32837879 | Early diagnosis and detection of triazole resistance are essential for appropriate antifungal therapy to improve outcome in patients with coronavirus associated invasive aspergillosis. | 2020-08-25 |
| 32837880 | This report highlights the need to define the available tools for diagnosis of invasive aspergillosis in severe COVID-19 patients. | 2020-08-25 |
| 32837889 | Transdiagnostic interventions, such as Acceptance and Commitment Therapy, that target psychological flexibility may be useful as the impact of the pandemic continues to unfold. | 2020-08-25 |
| 32837890 | Pattern differentiation-guided prescription is the practice style taught in the national syllabus among universities of Traditional Chinese Medicine in China, yet the lack of relevant diagnostic research reduces its reliability and hinders its implementation. | 2020-08-25 |
| 32837896 | Future clinical trials on vitamin D should consider the sources of heterogeneity in the existing experimental research and design trials that account for baseline status, evaluate the potential for prevention and treatment in at risk populations, standardize dosing strategies, assess product quality, assess outcomes according to gold standard definitions/diagnostic methods, and delineate viral ARTI from other causes when possible. | 2020-08-25 |
| 32837902 | Amidst the COVID-19 pandemic, clinicians have been plagued with dilemmas related to the uncertainty about diagnostic testing for the virus. | 2020-08-25 |
| 32837918 | That why it is extremely important to develop artificial intelligence-based automatic diagnostic tools to classify the Coronavirus outbreak. | 2020-08-25 |
| 32837944 | We should be aware of utmost importance of effective use of full or enhanced Personal Protective Equipment during diagnostic and therapeutic procedures. | 2020-08-25 |
| 32837945 | Foreign body cases should undergo a computed tomography scan to avoid diagnostic bronchoscopies. | 2020-08-25 |
| 32837949 | In this article, we propose essential steps that can be implemented at the departmental and institutional levels to do endoscopic diagnostic procedures effectively during COVID-19 outbreak and to break the transmission chain. | 2020-08-25 |
| 32837965 | The SARS-Cov-2 pandemic influenced the time of diagnosis of appendicitis, as well as its course, and mean hospital stay. […] As a result of the significant circumstances, delaying diagnosis and treatment of AA during SARS-Cov-2 pandemic, inappropriate management of this common surgical disorder has been noticed. | 2020-08-25 |
| 32837969 | Here, we focus on symptoms and the development of fast diagnosis methods, as well as potential management to prevent or treat the Covid-19 infection. | 2020-08-25 |
| 32837973 | Different countries took different approaches for the diagnosis of COVID-19. […] The assay design formats were available in the public domain and thereby allowing researchers to replicate them to make diagnostic kits. […] Consequently, several antigen or antibody-based diagnostic tests were also developed for the diagnosis of COVID-19. | 2020-08-25 |
| 32837978 | Those data were extracted by using the techniques of Python Web Scraping and preprocessed with Pandas Data Wrangling. | 2020-08-25 |
| 32838007 | As one of the important examination methods for the Corona Virus Disease 2019 (COVID-19), Computed Tomography (CT) examination plays an important role in the clinical discovery of suspected cases, diagnosis, and treatment review. […] This paper reviews the published papers in order to offer help in early clinical screening, disease diagnosis, disease severity determination and post-treatment review. | 2020-08-25 |
| 32838020 | The increasing rate of the number of infected individuals and its high mortality necessitates an immediate development of proper diagnostic methods and effective treatments. | 2020-08-25 |
| 32838035 | The Polyphony programme is a rapidly established collaboration whose aim is to build and maintain a collection of current healthcare knowledge about detection, diagnosis and treatment of COVID-19 infections, and use Artificial Intelligence (knowledge engineering) techniques to apply the results in patient care. | 2020-08-25 |
| 32838038 | An effective, point-of-care (POC) diagnostic tool could mitigate healthcare system strain, protect healthcare professionals, and support quarantine efforts. | 2020-08-25 |
| 32838076 | The Covid-19 pandemic is a global challenge presenting clinicians with an evolving diagnostic landscape. […] Electroencephalography has a unique place in the diagnostic work-up of impaired consciousness, a frequent feature of severe Covid-19. | 2020-08-25 |
| 32838092 | The implications of changes to management will be determined and the impact of a COVID-19 diagnosis on the patient’s breast cancer management will be determined. | 2020-08-25 |
| 32838103 | During these unprecedented times providers and patients are imperiled and resources for diagnosis and care may be limited. | 2020-08-25 |
| 32838105 | Concerns about potential COVID-19 consequences in a LT candidate were overruled by the severity of liver disease (MELD 36), forcing our team to proceed with an urgent successful LT as soon as 9 days after the COVID-19 diagnosis, 2 days after the first negative SARS-CoV-2 RNA by a nasopharyngeal swab and 1 day after the confirmation of its negativity on bronchoalveolar lavage. | 2020-08-25 |
| 32838106 | Diagnosis of COVID-19 was assessed by symptomatology, reverse transcriptase-polymerase chain reaction (RT-PCR), and computed tomography (CT) scan. | 2020-08-25 |
| 32838107 | Conclusion: Liver clinic visits, hepatoma surveillance, and diagnostic abdominal imaging fell dramatically as social distancing measures were instituted. | 2020-08-25 |
| 32838111 | Best practice for prevention, diagnosis, and management of venous thromboembolism (VTE) in patients with SARS-CoV-2 disease 2019 (COVID-19) is unknown due to limited published data in this population. […] Physicians were queried about their current approach to prophylaxis, diagnosis, and treatment of VTE in patients with COVID-19 using an online survey tool distributed through multiple international organizations between April 10 and 14, 2020. 515 physicians responded from 41 countries. […] Respondents reported the use of bedside testing when unable to perform standard diagnostic imaging for diagnosis of VTE. 291 respondents reported observing thrombotic complications in their patients with 64% noting that the complication was pulmonary embolism (PE). | 2020-08-25 |
| 32838117 | Like all other elective services, sleep medicine services suffered a partial deadlock due to the closing down of the sleep disorders diagnostic and therapeutic services, although clinical consultations and follow-ups, carried on remotely, allowed some mitigation. | 2020-08-25 |
| 32838125 | One of the solution to control the current havoc can be the diagnosis of disease with the help of various AI tools. […] Feature engineering was performed using techniques like Term frequency/inverse document frequency (TF/IDF), Bag of words (BOW) and report length. | 2020-08-25 |
| 32838146 | To date, few cases of COVID-19 meningitis have been confirmed, but it must remain in the differential diagnosis for patients with headache and fever. | 2020-08-25 |
| 32838155 | Techniques such as imprint cytology can be preferred over frozen sections for evaluation of the surgical margins especially in COVID-19 positive patients. | 2020-08-25 |
| 32838176 | With over eight million individuals infected and exceeding 400,000 deaths globally, the necessity to develop fast and efficient diagnostic methods is of high importance. […] This paper reports on currently available diagnostic screening methods for patients infected with SARS-CoV-2 to guide frontline healthcare workers involved with the diagnosis of 2019 novel coronavirus disease (COVID-19) patient. […] The preferred diagnostic approach is the reverse transcription (RT) of the virus’ ribonucleic acid (RNA) followed by polymerase chain reaction (PCR) amplification (RT-PCR). […] In improving the speed and efficiency of diagnostics, newer rapid diagnostic serological tests are in development for testing SARS-CoV-2, each with its unique advantages and disadvantages. […] They could potentially be used as triage tests to rapidly identify patients who are very likely to have COVID-19 in combination with other accurate diagnostic methods, such as diagnostic imaging. […] A combination of the disease history, clinical manifestations, laboratory diagnostic testing, and diagnostic imaging is crucial for making an accurate and useful diagnosis for COVID-19. […] Hopefully, the continuous development and use of rapid diagnostic tests and the implementation of public health measures will help control the spread of the disease. | 2020-08-25 |
| 32838187 | Therefore, we have provided suggestions for the diagnosis, treatment, and prevention of the novel coronavirus pneumonia in the current epidemic situation based on the latest reports and the experience of doctors treating COVID-19 in our hospital. | 2020-08-25 |
| 32838234 | An effective reduction in transmission must have occurred nearly immediately after the tighter lockdown, given the lag time of around 10 days from asymptomatic infection to diagnosis. | 2020-08-25 |
| 32838241 | Delirium may be one of the presenting symptoms of COVID-19, complicating diagnosis and care of elderly patients with dementia. | 2020-08-25 |
| 32838274 | To compare sociodemographic and clinical characteristics of pregnant women with and without SARS-CoV2 infection and, among those with SARS-CoV2, to compare characteristics of those who reported COVID-19 symptoms and those who were asymptomatic at diagnosis. […] Of the 101 women who tested positive, 77 (76.2%) were symptomatic at the time of diagnosis. | 2020-08-25 |
| 32838277 | To determine if significant placental histopathological changes occur after diagnosis of SARS-CoV-2 infection in pregnancy and whether these changes are correlated with the presence or absence of symptoms associated with infection. […] Histopathological characteristics were evaluated in each placenta and the incidence of these findings were compared between placentas after diagnosis of maternal SARS-CoV-2 infection and historical controls, as well as between placentas from patients with or without typical symptoms related to infection. […] A total of 50 placentas after diagnosis of maternal SARS-CoV-2 infection and 50 historical controls were analyzed. […] All patients had diagnosis of SARS-CoV-2 infection in the third trimester. […] Based on our data, there are no significant placental histopathological changes that occur after diagnosis of SARS-CoV-2 infection in the third trimester of pregnancy compared to a gestational age-matched historical control group. | 2020-08-25 |
| 32838286 | The assays developed in the present study offer alternative diagnostic tests for COVID-19. | 2020-08-25 |
| 32838292 | Given the rapid global spread of novel Corona Virus Disease (COVID-19), coupled with the high rate of missed diagnosis of viral sepsis caused by SARS-CoV-2 infection, it is urgent to evaluate the multiple organ failure score and viral sepsis in COVID-19 patients, so as to determine the clinical characteristics of viral sepsis more accurately and reveal the risk factors related to mortality. […] Therefore, we strongly suggest to daily evaluate SOFA score and MOD score in severe and critically-ill COVID-19 patients, so as to early diagnose and prevention of sepsis and MODS.Given the rapid global spread of novel Corona Virus Disease (COVID-19), coupled with the high rate of missed diagnosis of viral sepsis caused by SARS-CoV-2 infection, it is urgent to evaluate the multiple organ failure score and viral sepsis in COVID-19 patients, so as to determine the clinical characteristics of viral sepsis more accurately and reveal the risk factors related to mortality. | 2020-08-25 |
| 32838297 | The immediate actions from both academia and industry have led to the development of many COVID-19 diagnostic systems that have secured fast-track regulatory approvals and have been serving our healthcare frontlines since the early stage of the pandemic. […] On diagnostic technologies, many of these clinically validated systems have significantly benefited from the recent advances in micro- and nanotechnologies in terms of platform design, analytical method, and system integration and miniaturization. […] The continued development of new diagnostic platforms integrating micro- and nanocomponents will address some of the shortcomings we have witnessed in the existing COVID-19 diagnostic systems. […] This Perspective reviews the previous and ongoing research efforts on developing integrated micro- and nanosystems for nucleic acid-based virus detection, and highlights promising technologies that could provide better solutions for the diagnosis of COVID-19 and other viral infectious diseases. | 2020-08-25 |
| 32838309 | Data about COVID-19 exposure or diagnosis were collected. | 2020-08-25 |
| 32838332 | The differential diagnosis included post-infarction pericarditis and mechanical complications, thrombolysis, Dressler syndrome, and viral pericarditis. […] The histopathologic examination of the pericardial tissue sample and electron microscopic examination established the diagnosis. | 2020-08-25 |
| 32838351 | Significant delays in the rapid development and distribution of diagnostic testing for SARS-CoV-2 (COVID-19) infection have prevented adequate public health management of the disease, impacting the timely mapping of viral spread and the conservation of personal protective equipment. […] We developed a SARS-CoV-2 diagnostic medium-throughput qRT-PCR assay with rapid turnaround time and utilized this Clinical Laboratory Improvement Amendments (CLIA)-certified assay for testing nasopharyngeal swab samples from BMC patients, with emergency authorization from the Food and Drug Administration (FDA) and the Massachusetts Department of Public Health. | 2020-08-25 |
| 32838355 | Patients hospitalized within 24 h of diagnosis were classified based on their exposure to hydroxychloroquine alone (HC) or with azithromycin (HC+AZ) or no HC as treatments. | 2020-08-25 |
| 32838356 | In this issue of Med, Vanuytsel and colleagues1 demonstrate how academic institutions are stepping up to the forefront of SARS-CoV-2 testing by rapidly implementing a COVID-19 diagnostic test at a large safety net hospital serving an at-risk population, providing a regulatory and logistical roadmap to broaden testing capacity. | 2020-08-25 |
| 32838380 | Respiratory co-infections have the potential to affect the diagnosis and treatment of COVID-19 patients. […] Knowledge of the prevalence and type of co-infections may have diagnostic and management implications. | 2020-08-25 |
| 32838389 | Worldwide efforts sprouted to coordinate proper response by increasing surge capacity and optimizing diagnosis and containment. | 2020-08-25 |
| 32838396 | The nomogram may be incorporated to existing diagnostic algorithm to effectively stratify suspected patients for SARS-CoV-2 pneumonia. | 2020-08-25 |
| 32838398 | We conducted a prospective diagnostic study performing a blood differential analyzing morphologic changes in peripheral blood of COVID-19 patients. […] We defined a hematologic COVID-19 pattern to facilitate further independent diagnostic analysis and to investigate the impact on the hematologic system during the clinical course of COVID-19 patients. | 2020-08-25 |
| 32838400 | A high percentage of smudge cells is associated with CLL diagnosis and has an important prognostic value: better survival and prolonged time to first treatment. | 2020-08-25 |
| 32838815 | We would like to share the sentinel roadmap for screening and diagnosis of COVID-19 to medical healthcare workers around the world, especially countries who are facing great challenges to cope with COVID-19 and meanwhile with limited medical resources. | 2020-08-26 |
| 32839069 | Despite imaging not being a tool for novel coronavirus disease 2019 (COVID-19) diagnosis, there has been an increased number of chest computed tomography (CT) scans done worldwide. […] In this pictorial review, we have summarized the most reported imaging features of COVID-19 pneumonia, including possible differential diagnosis according to the CT finding. | 2020-08-26 |
| 32839075 | These changes concern 4 areas of orthodontic practice: (1) microbiologic control measures, with increased use of personal protective equipment, stricter protocols inside and outside of the clinical area, and minimization of procedures that generate aerosols; (2) social distancing measures by redistributing spaces and decreasing the number of patients and companions in the clinics; (3) increasing teleorthodontics and use of appliances and techniques that require fewer scheduled and urgent appointments; and (4) bioethical considerations that promote a broader view of the psychosocial aspects of patients, their families, and the community. | 2020-08-26 |
| 32839250 | In addition to providing critical data informing inactivation methods and risk assessments for diagnostic and research laboratories working with SARS-CoV-2, these data provide a framework for other laboratories to validate their inactivation processes and to guide similar studies for other pathogens. | 2020-08-26 |
| 32839385 | An electrocardiogram was taken on these patients within the first 48 h after diagnosis and before the administration of any medication with a known effect on QT interval. | 2020-08-26 |
| 32839667 | There were no significant differences in age, gender, therapy, diagnosis or comorbidities across clusters. | 2020-08-26 |
| 32839734 | Building on the prior work on cough-based diagnosis of respiratory diseases, we propose, develop and test an Artificial Intelligence (AI)-powered screening solution for COVID-19 infection that is deployable via a smartphone app. […] This makes the diagnosis of a COVID-19 infection by cough alone an extremely challenging multidisciplinary problem. | 2020-08-26 |
| 32839923 | Episodes with a primary diagnosis of Mood disorders lead the decrease on psychiatric ED visits with 68·3% less episodes. […] Schizophrenia and other psychotic disorders was the diagnosis group with the smaller decline (9·8% decrease). | 2020-08-26 |
| 32840002 | A proportion of 11.8% of individuals tested positive for SARS-CoV-2 by NP swab PCR greater than 14 days after the resolution of symptoms of active disease, including one donor who had asymptomatic disease and tested positive by NP swab 41 days after her initial diagnosis. | 2020-08-26 |
| 32840148 | This article reports in detail the diagnosis and treatment process for two patients with confirmed COVID-19 and analyzes the results of the SARS-CoV-2 nucleic acid tests that were used for different types of specimens (sputum from deep cough, nasopharyngeal swab, and feces). […] Our findings provide a reference for selecting the most suitable specimen for the clinical diagnosis of COVID-19 and improving the positive detection rate. | 2020-08-26 |
| 32840240 | Furthermore, this condition constitutes a diagnostic challenge, particularly in the era of COVID-19 infection. […] Here, we report a case of rifampicin-induced pneumonitis with clinical, imaging, and histological features of acute respiratory distress syndrome (ARDS), which required severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing to exclude a diagnosis of coronavirus disease 2019 (COVID-19) pneumonia. […] CONCLUSIONS This case highlights the importance of early, rapid, and accurate testing for SARS-CoV-2 during the COVID-19 pandemic for patients presenting with acute respiratory symptoms, so that accurate diagnosis and early patient management are not delayed for patients with treatable causes of acute and severe lung diseases. | 2020-08-26 |
| 32840399 | The diagnostic value of specific antibody detection is limited. | 2020-08-26 |
| 32840560 | We have also covered the diagnosis, therapeutics and vaccine status of SARS-CoV-2. | 2020-08-26 |
| 32840606 | Ten remained asymptomatic at the time of COVID-19 diagnosis by reverse-transcription polymerase chain reaction, which was on average 20 days after exposure. | 2020-08-26 |
| 32840663 | Rapid diagnosis of patients with SARS-CoV‑2 infection together with assessment of disease severity and awareness of organ failure are the mainstays of emergency care. […] Adjunctive diagnostic measures which enhance diagnostic specificity are lung ultrasound, x‑ray, and computed tomography of the lungs. | 2020-08-26 |
| 32841117 | Unlike many other states across America that struggled to get enough diagnostic tests for coronavirus 2019 disease (COVID-19) this past spring, New Mexico was able to not only meet the demand for testing symptomatic patients, but was able to begin expanding its screening to asymptomatic individuals. | 2020-08-26 |
| 32841342 | There have been several guidance statements focusing on the management of VTE in hospitalized and critically ill patients with COVID-19, including the most recent statement by the Scientific and Standardization Committee of the International Society of Thrombosis and Haemostasis, which includes comprehensive guidance on the diagnosis, prevention, and treatment of VTE in this patient population. | 2020-08-26 |
| 32841659 | Besides, GRP78 targeting is used in diagnosis and imaging modalities using radionuclides. […] This review summarizes the various attempts that used GRP78 both in therapy (fighting cancer, viral and fungal infections) and diagnosis (imaging). | 2020-08-26 |
| 32841703 | Risk of missed or late diagnosis of COVID-19 was high during the UK’s initial ‘containment phase’, because of strict criteria for testing. | 2020-08-26 |
| 32842383 | All specimens were tested for 2019-nCoV nucleic acid by two diagnostic kits from different manufacturers. | 2020-08-27 |
| 32842563 | OGA were cardinal symptoms of COVID-19, which may serve as clues for early diagnosis. […] Diagnostic testing for SARS-CoV-2 was suggested in patients with OGA during the COVID-19 pandemic to ensure timely diagnosis and appropriate quarantine. | 2020-08-27 |
| 32842601 | The global burden of coronavirus disease 2019 (COVID-19) to public health and global economy has stressed the need for rapid and simple diagnostic methods. […] In recent years, many plasmonics’ platforms have embraced the challenge of offering on-site strategies to complement traditional diagnostic methods relying on the polymerase chain reaction (PCR) and enzyme-linked immunosorbent assays (ELISA). | 2020-08-27 |
| 32842818 | In this review, we summarize the epidemiology, pathophysiology, and diagnosis of COVID-19. | 2020-08-27 |
| 32842849 | Specialists will need to consider the unique needs of their populations in ensuring quality care, as diagnostic differences and patient age will impact participation in teleNP. | 2020-08-27 |
| 32842909 | In this coronavirus 2019 (COVID-19) era, when pneumonitis occurs in patients with lung cancer receiving immune checkpoint inhibitors (ICIs), a major challenge is to make a rapid and correct differential diagnosis among drug-induced pulmonary toxicity, tumour progression, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced pneumonitis. […] While waiting for polymerase chain reaction (PCR) testing results, an accurate evaluation of the symptoms and serologic features can help us make a first diagnostic hypothesis and quickly start correct treatment. […] Physicians need a collaborative effort to develop and share a common database reporting clinical (anosmia, dysgeusia), serologic, and radiologic data in ICI-treated patients with lung cancer developing interstitial disease to create an evidence-based clinical diagnostic algorithm. | 2020-08-27 |
| 32843064 | An accurate diagnosis of this disease in the clinic is very important. […] The sensitivity and specificity of the combination of age, white blood cell count, and ground-glass opacity in the diagnosis of COVID-19 were 92.7 and 66.1%, respectively. […] Age, white blood cell count and ground-glass opacity have high accuracy in the early diagnosis of COVID-19 and the differential diagnosis from CAP. […] This result provides certain significant guidance for the diagnosis and treatment of new coronavirus pneumonia. | 2020-08-27 |
| 32843098 | Confirmed diagnosis of SARS-CoV-2 infection, by RT-PCR. […] Diagnosis of Acute Respiratory Distress Syndrome (hypoxemic respiratory failure not explained by cardiac disease + PaO2/FiO2 ratio < 300 with a Positive End-Expiratory Pressure ≥ 5 cm H2O + bilateral pulmonary infiltrates) Length of mechanical ventilation of at least 72 hours Informed consent (next of kin / legal guardian) Exclusion criteria: Pregnant or breast-feeding women. | 2020-08-27 |
| 32843111 | Moreover, this theory offers an alternative solution in case where machine learning techniques and long-term memory models are inapplicable because they need a considerable amount of data to be performant. | 2020-08-27 |
| 32843150 | We compared the number of elective consultations and diagnostic urologic examinations, number and type of elective surgeries, as well as patients’ demographic characteristics and main causes of presentation to Urology Emergency Department (ED) during the two mentioned periods MATERIALS AND METHODS: Data from 691 patients coming to emergency department were collected from institutional clinical software from March 18 th 2020 to May 2 nd 2020 - and from the same period the previous year. […] Data collected were age, sex, day of the presentation to Emergency Department, referral from other hospitals, triage color, reason of admission, diagnosis of discharge, and the need for emergency surgery or hospitalization. | 2020-08-27 |
| 32843326 | We describe the measures taken by West China Hospital of Sichuan University to address the diagnosis, prevention and treatment of the infection. | 2020-08-27 |
| 32843381 | A positive COVID-19 throat swab, in addition to bilateral pneumonia on chest X-ray and lymphopaenia in his blood tests, confirmed a diagnosis of COVID-19 pneumonia. | 2020-08-27 |
| 32843467 | This case illustrates that subacute thyroiditis associated with viruses such as SARS-CoV-2 should be recognised as a complication of COVID-19 and considered as a differential diagnosis when infected patients present with tachycardia without evidence of progression of COVID-19 illness. | 2020-08-27 |
| 32843845 | Patients scheduled for surgery may benefit from a preoperative diagnostic testing for SARS coV2 infection if they have been in close contact with a COVID-19 patient, or if they are symptomatic or in case of major surgery. | 2020-08-27 |
| 32843849 | As the new cases of COVID-19 are growing every daysince January 2020, the major way to control the spread wasthrough early diagnosis. […] Prevention and early diagnosis are the key strategies followed by most countries. […] Further, the diagnostic methods and the advancement of the computerized tomography have been discussed. […] In addition, the current diagnostic methods for COVID-19 including Immunoglobulin M (IgM) and Immunoglobulin G (IgG)and chest computed topography(CT) scan, reverse transcription-polymerase chain reaction (RT-PCR) andimmunochromatographic fluorescence assay, are also discussed in detail. | 2020-08-27 |
| 32843887 | X-ray images could be classified using the machine learning techniques to specify if the person infected severely, mild, or not infected. […] Many techniques have been proposed to overcome ISP. | 2020-08-27 |
| 32844161 | In this case series, patients were considered eligible if they were older than 18 years, with premortem diagnosis of severe acute respiratory syndrome coronavirus 2 infection and COVID-19 listed clinically as the direct cause of death. | 2020-08-27 |
| 32844172 | Therefore, in the current pandemic, providing a fast-track algorithm for scientifically standardized diagnostic criteria and treatment recommendations for patients with lung cancer is urgent. | 2020-08-27 |
| 32844526 | Finding a rapid, easy-to-use, and cheap diagnostic method is necessary to help control the current outbreak. […] Microfluidic systems provide a platform for many diagnostic tests, including RT-PCR, RT-LAMP, nested-PCR, nucleic acid hybridization, ELISA, fluorescence-Based Assays, rolling circle amplification, aptamers, sample preparation multiplexer (SPM), Porous Silicon Nanowire Forest, silica sol-gel coating/bonding, and CRISPR. […] This paper provides an overview of microfluidic systems as diagnostic methods for RNA viruses with a focus on SARS-CoV-2. | 2020-08-27 |
| 32844713 | The epitopes we identified in this study may serve as vaccine candidates to elicit neutralizing antibodies in most vaccinated people or specific antigens for SARS-CoV-2 diagnosis. | 2020-08-27 |
| 32844739 | To validate the specimen-pooling strategy for real-time reverse transcription PCR detection of severe acute respiratory syndrome coronavirus 2, we generated different pools including positive specimens, reflecting the distribution of cycle threshold values at initial diagnosis. | 2020-08-27 |
| 32844798 | There are some newly developed and promising methods for detection of SARS-CoV-2, in order to facilitate the development of novel approaches for early diagnosis. | 2020-08-27 |
| 32844799 | We aimed here to discuss about the current diagnostic methodology for detecting the SARS-CoV-2 in health laboratories. […] Here we use the Novel Corona virus (2019-nCoV) Nucleic Acid Diagnostic Kit (PCR-Fluorescence Probing) which is a real time reverse transcription polymerase chain reaction (rRT-PCR) test. | 2020-08-27 |
| 32844901 | A positive real-time reverse-transcriptase polymerase chain reaction (RT-PCR) for SARS CoV-2, from nasopharyngeal swabs, is the current gold standard diagnostic test for this virus and has sensitivity of 60-70%. […] Systematic review of comparative studies of diagnostic accuracy within the Evidence-based Health Program of a federal university in São Paulo (SP), Brazil. […] A systematic search of the relevant literature was conducted in the PubMed, EMBASE, Cochrane Library, CINAHL and LILACS databases, for articles published up to June 6, 2020, relating to studies evaluating the diagnostic accuracy of RT-PCR and chest CT for COVID-19 diagnoses. | 2020-08-27 |
| 32844915 | This manuscript aims to summarize the changes adopted by the General and GI Surgery Departments to address this unprecedented clinical scenario, including the restructuring of surgical schedules, staff preparation, and the departments outbreak response protocols and recommendations for surgical techniques and risk management. | 2020-08-27 |
| 32844985 | At that time there were not enough diagnostic tests to identify infected individuals and data were strongly associated with sub notifications. | 2020-08-27 |
| 32845192 | In this article, we summarized the knowledge about the causative pathogen of COVID-19 and various diagnostic methods in this pandemic for better understanding of the limitations and the nuances of virus testing for COVID-19. | 2020-08-27 |
| 32845525 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting COVID-19 pandemic present important diagnostic challenges. […] Several diagnostic strategies are available to identify or rule out current infection, identify people in need of care escalation, or to test for past infection and immune response. […] Point-of-care antigen and molecular tests to detect current SARS-CoV-2 infection have the potential to allow earlier detection and isolation of confirmed cases compared to laboratory-based diagnostic methods, with the aim of reducing household and community transmission. […] To assess the diagnostic accuracy of point-of-care antigen and molecular-based tests to determine if a person presenting in the community or in primary or secondary care has current SARS-CoV-2 infection. […] We included all reference standards to define the presence or absence of SARS-CoV-2 (including reverse transcription polymerase chain reaction (RT-PCR) tests and established clinical diagnostic criteria). […] Any future research study report should conform to the Standards for Reporting of Diagnostic Accuracy (STARD) guideline. | 2020-08-27 |
| 32845730 | Several variations of manual techniques and-lift assisted techniques were identified in addition to a specialized proning bed. | 2020-08-27 |
| 32845805 | In this special issue of the Ear Nose and Throat (ENT) journal entitled Lasers in Otolaryngology, we attempted to cover and accommodate different experiences from around the globe on both established and some not so well-known techniques and indications for Lasers in most ENT subspecialties. | 2020-08-27 |
| 32845849 | Chest computed tomography (CT) becomes an effective tool to assist the diagnosis of coronavirus disease-19 (COVID-19). […] Due to the outbreak of COVID-19 worldwide, using the computed-aided diagnosis technique for COVID-19 classification based on CT images could largely alleviate the burden of clinicians. | 2020-08-27 |
| 32846177 | Such types of approaches trigger the scientists and policymakers in the development of a conceptual framework of nano-biotechnology by linking nanoscience and virology to present a smart molecular diagnosis/treatment for pandemic viral infections. | 2020-08-27 |
| 32846885 | Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-COV2) outbreak in China at the end of 2019, clinicians relied on diagnostic imaging to characterize the disease’s extension and severity […]. | 2020-08-28 |
| 32847008 | Therefore, many efforts are currently being developed to improve therapy and diagnosis, as well as to produce inhibitory drugs and biosensors for a rapid, minimally invasive, and effective detection. | 2020-08-28 |
| 32847728 | However, guidelines for the diagnosis of COVID-19 myocarditis have not been established. […] Guidelines for diagnosis and management of COVID-19 myocarditis have not been established and our knowledge on management is rapidly changing. | 2020-08-28 |
| 32847818 | Other complications, such as postinfectious demyelination, encephalitis, and seizures, occur less often, but are probably under-reported given the lack of diagnostic information, such as cerebrospinal fluid sampling and electroencephalogram monitoring. | 2020-08-28 |
| 32847836 | Permission for caregivers to attend clinic visits was limited in many centres, with some exceptions (ie, for non-autonomous patients, in the case of a new diagnosis, when bad news was expected and for terminally ill patients). | 2020-08-28 |
| 32847961 | A review of the literature yields descriptive studies in pediatric patients; however, no evidence-based or evidence-informed guidelines for the diagnosis and treatment of the hospitalized pediatric patient have been published in peer-reviewed journals. […] The authors, working at a quaternary care children’s hospital in the national epicenter of the SARS-CoV-2 pandemic, found an urgent need to create a unified, multidisciplinary, evidence-informed set of guidelines for the diagnosis and management of coronavirus disease 2019 in children. | 2020-08-28 |
| 32848011 | This study showed that the RT-LAMP assay was a simple, rapid, and sensitive approach for SARS-CoV-2 infection and can facilitate COVID-19 diagnosis, especially in resource-poor settings. | 2020-08-28 |
| 32848097 | Among patients with COVID-19 hospitalised at the peak of the epidemic in China, fever, cough, and dyspnoea were the main symptoms at initial diagnosis, accompanied by lymphocytopenia and hypoxaemia. | 2020-08-28 |
| 32848328 | The surge in demand for digital medical solutions has been accelerated by the need for new diagnostic and therapeutic methods in the current coronavirus disease 2019 pandemic. | 2020-08-28 |
| 32848431 | This review provides an overview about the COVID-19 virus to increase public awareness and understanding of the virus and its consequences in terms of history, epidemiology, structure, genome, clinical symptoms, diagnosis, prevention, and treatment. | 2020-08-28 |
| 32848446 | In this article, we have reviewed the prevalence, diagnosis, symptoms, and treatment of COVID-19 in children. | 2020-08-28 |
| 32848487 | The result categorized into two distinct clinical areas: treatment (18 articles) and diagnostic (23 articles) services. | 2020-08-28 |
| 32849449 | Predominantly, we identified potential epitope-based vaccine candidates, siRNA-based therapeutic regimens, and diagnostic primers. […] Further, experimentally confirmed and designed diagnostic primers are earmarked in the primers section. | 2020-08-28 |
| 32849952 | Radiographic findings and distinctive laboratory results led to prompt testing by nasopharyngeal polymerase chain reaction (PCR), which ultimately confirmed the proposed diagnosis. […] To our knowledge, this is the first case to describe how EA, a rare cause of abdominal pain, indirectly led to the diagnosis of COVID-19. | 2020-08-28 |
| 32850041 | In common praxis, the diagnosis of COVID-19 is based on a positive PCR result. […] To avoid this, a comprehensive view of lab-results, radiology, clinical symptoms and comorbidities is necessary for the correct diagnosis or exclusion of COVID-19. | 2020-08-28 |
| 32850107 | After diagnosis of COVID-19, this PD patient had worsening of motor symptoms, complicated with acute hypoxemic respiratory failure, urinary tract infection, and acute encephalopathy. | 2020-08-28 |
| 32850198 | Definitive diagnosis was by a positive real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens, and high-resolution computed tomography (HRCT) finding of new-onset ground-glass opacities on the very first day of admission that was the presenting day. | 2020-08-28 |
| 32850199 | It is important to know and report new findings of novel diseases not only for diagnosis and treatment but also to place appropriate isolation precautions and containment. | 2020-08-28 |
| 32850443 | However, for infected or suspected infected cancer patients, their experiences in terms COVID-19 diagnosis, anticancer treatment and prognosis are largely unknown and controversial. […] Here, we summarize the incidence, severe illness rate and mortality according to the published clinical data of COVID-19 in cancer patients and discuss the diagnostic difficulties, anticancer treatment and prognosis of COVID-19-infected cancer patients. | 2020-08-28 |
| 32850461 | Moreover, in some regions in Italy even the very first non-urgent visits have been postponed with the consequent delay in diagnosis, which may negatively affect disease prognosis. | 2020-08-28 |
| 32850506 | Our findings are critical for the diagnosis of SARS-CoV-2 infection and for determining deadline of restriction measures to prevent transmission caused by convalescent patients with COVID-19. | 2020-08-28 |
| 32850602 | We examine the fundamental concepts including the origin, virology, pathogenesis, clinical manifestations, diagnosis, laboratory, radiology, and histopathologic findings, complications, and treatment. | 2020-08-28 |
| 32850608 | More specifically, the majority of HCWs rated their HCFs as very poor or poor in term of availability of the following: an adequate number of mechanical ventilators (88.8%), diagnostic devices (88.2%), ICU rooms and beds (81.4%), and isolation rooms (79.7%). | 2020-08-28 |
| 32851474 | This paper describes three autopsy cases with postmortem diagnosis of SARS-CoV-2 infection, with detailed macroscopic examination as well as advanced microscopic studies of organ tissues collected using hematoxylin-eosin stains and immunohistochemical markers. | 2020-08-28 |
| 32852419 | Although imaging should not be used for first-line screening or diagnosis, radiologists need to be aware of its imaging features, and those of common conditions that may mimic COVID-19 pneumonia. | 2020-08-28 |
| 32852420 | Infections of the cardiovascular system may present with nonspecific symptoms, and it is common for patients to undergo multiple investigations to arrive at the diagnosis. […] Echocardiography is central to the diagnosis of endocarditis and pericarditis. […] However, cardiac computed tomography (CT) and magnetic resonance imaging also play an additive role in these diagnoses; in fact, magnetic resonance imaging is central to the diagnosis of myocarditis. […] Functional imaging (fluorine-18 fluorodeoxyglucose-positron emission tomography/CT and radiolabeled white blood cell single-photon emission computed tomography/CT) is useful in the diagnosis in prosthesis-related and disseminated infection. | 2020-08-28 |
| 32852513 | Mean initial response time, agreement between the teleophthalmology diagnosis and final diagnosis, treatment and management following recommendations outlined in the Joint Trauma System clinical practice guidelines, prevention of the need for aeromedical evacuation, user satisfaction, and security and the Health Insurance Portability and Accountability Act compliance of consult. […] There was agreement between the teleophthalmology diagnosis and final diagnosis in 24 consults (86%; 95% CI, 72%-100%). | 2020-08-28 |
| 32852623 | Covid-19 was classified as (1) definite diagnosis of Covid-19 disease: presence of symptomatic Covid-19 infection, confirmed by positive oral/nasopharyngeal swabs; (2) highly suspected Covid-19 disease: presence of highly suggestive symptoms, in absence of a swab test. […] A significantly higher prevalence of patients with definite diagnosis of Covid-19 disease, or with highly suspected Covid-19 disease, or both the conditions together, was observed in the whole autoimmune systemic disease series, compared to “Italian general population” (p = .030, p = .001, p = .000, respectively); and for definite + highly suspected diagnosis of Covid-19 disease, in patients with autoimmune systemic diseases of the three regions (p = .000, for all comparisons with the respective regional general population). […] Moreover, significantly higher prevalence of definite + highly suspected diagnosis of Covid-19 disease was found either in patients with various “connective tissue diseases” compared to “inflammatory arthritis group” (p < .000), or in patients without ongoing conventional synthetic disease-modifying anti-rheumatic drugs treatments (p = .011). | 2020-08-28 |
| 32852704 | After adjustment for covariates, night work and BMI > 30 were associated with a markedly greater risk of COVID-19 diagnosis (OR 3.049 [95%CI 1.260-7.380] and OR 7.15 [95%CI 2.91-17.51], respectively). | 2020-08-28 |
| 32852721 | Overall, 42,926 patients hospitalised between 21 February and 21 April 2020 with a diagnosis of COVID-19 confirmed by real-time polymerase chain reaction tests were included in this study. | 2020-08-28 |
| 32852883 | Using the LHS-integrated electronic medical records system, we were able to collect a large amount of clinical information including age, sex, socio-economic status, weight, height, body mass index, HbA1c, prior diagnosis of ischaemic heart disease, depression/anxiety, schizophrenia, dementia, hypertension, cerebrovascular accident, congestive heart failure, smoking, and chronic lung disease. […] A prior diagnosis of cerebrovascular accident and chronic lung disease conferred an increased risk of hospitalization but not obesity or smoking status. | 2020-08-28 |
| 32853011 | Criteria for a probable posttraumatic stress disorder diagnosis were met by a total of 16.7% (21.7% of women; 5.1% of men). | 2020-08-28 |
| 32853121 | Limited data are available on how a patient’s concomitant cancer diagnosis affected ethical concerns raised during the early stages of the pandemic. | 2020-08-28 |
| 32853158 | Factors exacerbating psychological distress include Hispanic ethnicity and a previous mental illness diagnosis. | 2020-08-28 |
| 32853163 | While the overall diagnostic specificity was rated as very high, sensitivity rates between 67 and 98% indicate considerable quality differences between the manufacturers, especially for IgA and IgM. | 2020-08-28 |
| 32853291 | Rapid and accurate diagnosis of this novel pathogen posts great challenges not only clinically but also technologically. […] In this study, we developed an isothermal, CRISPR-based diagnostic for COVID-19 with near single-copy sensitivity. […] The diagnostic performances of all three technology platforms were also compared. […] Our study aimed to provide more insights into the molecular detection of SARS-CoV-2, and also to present a novel diagnostic option for this new emerging virus. | 2020-08-28 |
| 32853320 | The global shortage of reagents and kits for nucleic acid extraction and molecular detection of SARS-CoV-2 requires new cost-effective strategies for the diagnosis of suspected COVID-19 cases, especially in countries that need to increase detection capacity. […] In conclusion, pooling nasopharyngeal samples with both automated and manual extraction proved reliable, and thus a potential efficient alternative for the diagnosis of suspected COVID-19 in developing countries. | 2020-08-28 |
| 32853453 | To optimize diagnostic workup of the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, we systematically reviewed neurological and neuroradiological manifestations of SARS-CoV-2 and all other known human coronavirus species (HCoV). […] Therefore, we propose practical imaging guidelines to facilitate the diagnostic workup and monitoring of patients infected with HCoVs. | 2020-08-28 |
| 32853490 | Finally, techniques are offered to render culturally competent care to African-Americans diagnosed with COVID-19 who present concomitantly with health disparities. | 2020-08-28 |
| 32853546 | We also consider existing nucleoside analogs and novel genomic techniques as potential anti-CoV therapeutics that could be used individually or in combination to target the proofreading mechanism. | 2020-08-28 |
| 32853978 | Studies using standard algorithms for clinically suspected VTE reported PE in 13% of patients (95% PI, 2%-57%) and DVT in 6% (95% PI, 0%-60%), compared to 11% (95% PI, 2%-46%) and 24% (95% PI, 2%-85%) in studies using other diagnostic strategies or patient sampling. […] The threshold for clinical suspicion should be low to trigger prompt diagnostic testing. | 2020-08-28 |
| 32853988 | All re-positive cases had mild or moderate symptoms at initial diagnosis and were younger on average (median, 28). | 2020-08-28 |
| 32854106 | The attenuation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, at least in Italy, allows a gradual resumption of diagnostic and therapeutic activities for sleep respiratory disorders. | 2020-08-28 |
| 32855021 | Modifications to common radiographic techniques have resulted from the challenges presented by the COVID-19 pandemic. | 2020-08-29 |
| 32855085 | This situation would affect the diagnosis and treatment of patients with STEMI. | 2020-08-29 |
| 32855181 | The development of diagnostic and research tools to determine infection and vaccine efficacy is critically needed. […] This type of rapid, surrogate neutralization diagnostic can be employed widely to help study SARS-CoV-2 infection and assess the efficacy of vaccines. | 2020-08-29 |
| 32855191 | 3D-printed nasopharyngeal swabs for COVID-19 molecular diagnostic testing address the national shortage of swabs. | 2020-08-29 |
| 32855214 | Diagnosis of COVID-19 was confirmed via viral reverse transcriptase PCR swab or supporting radiological evidence. | 2020-08-29 |
| 32855289 | Electrodiagnosis was demyelinating in 80.5% and levels 1 and 2 of Brighton criteria of diagnostic certainty, when applicable, were fulfilled in 94.5% patients. | 2020-08-29 |
| 32855306 | To evaluate the impact of faecal immunochemical testing (FIT) prioritisation to mitigate the impact of delays in the colorectal cancer (CRC) urgent diagnostic (2-week-wait (2WW)) pathway consequent from the COVID-19 pandemic. […] To construct the underlying models, we employed 10-year net CRC survival for England 2008-2017, 2WW pathway CRC case and referral volumes and per-day-delay HRs generated from observational studies of diagnosis-to-treatment interval. […] Prioritisation out of delay for the 18% of symptomatic referrals with FIT >10 µg Hb/g would avoid 89% of these deaths attributable to presentational/diagnostic delay while reducing immediate requirement for colonoscopy by >80%. […] Delays in the pathway to CRC diagnosis and treatment have potential to cause significant mortality and loss of life years. | 2020-08-29 |
| 32855827 | We describe two distinct cases of ST elevation on electrocardiogram occurring in patients with COVID-19 and review important diagnostic and management considerations for the front-line clinician. | 2020-08-29 |
| 32855992 | However, severe acute respiratory distress syndrome (ARDS) occurred, prompting the diagnosis of immune reconstitution inflammatory syndrome (IRIS). | 2020-08-29 |
| 32856269 | Details of admissions, operations, diagnostic procedures, outpatient reviews, morbidities and mortalities were recorded. | 2020-08-29 |
| 32856766 | The diagnosis of COVID-19 requires integration of clinical and laboratory data. […] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic assays play a central role in diagnosis and have fixed technical performance metrics. […] Our goal was to examine the clinical sensitivity of two most common SARS-CoV-2 diagnostic test modalities, polymerase chain reaction (PCR) and serology, over the disease course to provide insight into their clinical interpretation in patients presenting to the hospital. […] Superimposition of sensitivities over time indicate that serology can function as a reliable diagnostic aid indicating recent or prior infection. | 2020-08-29 |
| 32856817 | Moreover, the tools to overcome professional burnout and improve occupational safety are providing medical institutions with the required personnel in sufficient quantities to solve the tasks, providing diagnostic and medical equipment, as well as protective equipment. | 2020-08-29 |
| 32857112 | Among 71 symptomatic cases, 47 children (66%) had unrecognized symptoms before diagnosis, 18 (25%) developed symptoms after diagnosis, and only 6 (9%) were diagnosed at the time of symptom onset. | 2020-08-29 |
| 32857624 | In the history of medicine, autopsies and tissue sampling have played a fundamental role in order to understand the pathogenesis of emerging diseases, including infectious ones; compared to the past, histopathology can be now expanded by innovative techniques and modern technologies. | 2020-08-29 |
| 32858058 | Qualitative and quantitative detection of nucleic acids of SARS-CoV-2, the pathogen that causes coronavirus disease 2019 (COVID-19), plays a significant role in COVID-19 diagnosis, surveillance, prevention, and control. […] Reverse transcriptase quantitative PCR (RT-qPCR) and droplet digital PCR (ddPCR) were used for qualitative and quantitative analyses of these samples to evaluate the diagnostic performance and applicability of the two methods. […] Qualitative analysis of COVID-19 samples can meet the needs of clinical screening and diagnosis, while quantitative analysis provides more information to the research community. | 2020-08-29 |
| 32858315 | Herein, we present the first case of SARS-CoV-2 infection with manic-like symptoms and describe the diagnosis, clinical course, and treatment of the case, focusing on the identifications of SARS-CoV-2 in the specimen of cerebrospinal fluid (CSF). | 2020-08-29 |
| 32858533 | This case highlights the need for clinicians to have elevated vigilance with regard to screening and treatment for venous thromboembolism in high-risk patients, such as spinal cord injury with a concurrent diagnosis of coronavirus virus disease 2019. | 2020-08-29 |
| 32858554 | Where each individual symptom contributes to the clinical evaluation of possible infection, it is the combination of COVID-19 symptoms that could allow for a rapid diagnostic appraisal of the disease in a high prevalence setting. | 2020-08-29 |
| 32859408 | In about half of the cases, viral RNA could be detected in the stool, which is another line of transmission and diagnosis. covid19 has a worse prognosis in patients with comorbidities, although there is not enough evidence in case of previous digestive diseases. […] Digestive endoscopies may give rise to aerosols, which make them techniques with a high risk of infection. | 2020-08-30 |
| 32859676 | Rapid and ease-to-use diagnostic techniques are urgently needed to diagnose SARS-CoV-2 infection. […] We devised a reverse transcription multiple cross displacement amplification (RT-MCDA) coupled with nanoparticles-based biosensor (BS) assay (RT-MCDA-BS) for rapid, sensitive and specific diagnosis of COVID-19. […] The diagnosis results were visually reported using BS. | 2020-08-30 |
| 32859864 | This will lead to early diagnosis and specific management. | 2020-08-30 |
| 32860140 | Demographics, diagnosis and management were recorded along with Covid-19 testing and results. […] During 2020, the diagnosis of appendicitis increased (4.3 vs 18.8 per cent, p = < 0.05) as did severity (0 per cent > grade 1 vs 58.3 per cent > grade 1, p = < 0.05). | 2020-08-30 |
| 32860280 | The identification of factors that are associated with the enhanced prevalence of COVID-19 facilitates early diagnosis, and adequate and prompt treatment. | 2020-08-30 |
| 32860389 | In this context, Nuclear Medicine departments should reconsider and update their practices, by altering routines and workflows in order to comply with the new sanitary standards, triaging their appointments, or introducing new diagnostic methods like Tele-Medicine / Tele Nuclear Medicine and Artificial Intelligence applications. | 2020-08-30 |
| 32860390 | Due to the increased transmission rate of the virus, it became of great importance the early diagnosis of the disease. […] This review summarizes the different diagnostic tests available to the clinicians for the diagnosis and follow up of the SARS COV-2 infections. | 2020-08-30 |
| 32860395 | A critical task for health systems confronted with the spread of the coronavirus is to protect the health of all citizens, so this requires that both diagnosis/testing and appropriate care should be readily available, affordable, and provided in a safe environment. | 2020-08-30 |
| 32860396 | The objective of the current paper is to provide guidance on how diagnostic and therapeutic management of patients with thyroid diseases can be safely and effectively adjusted during pandemic, in nuclear medicine settings. | 2020-08-30 |
| 32860474 | In the United Hospital of Ancona, a specialist outpatient clinic dealing with diagnosis and treatment of immunomediated skin diseases has been operating since 1985, and 291 patients with hidradenitis suppurativa (HS) are currently being treated. | 2020-08-30 |
| 32860510 | While polymerase chain reaction-based assays are used for diagnosis, there is a need for high-throughput, rapid serologic methods. | 2020-08-30 |
| 32860682 | The survival benefit observed in patients receiving antifungal therapy implies that the proposed diagnostic and defining criteria are appropriate. […] Screening using a strategic diagnostic approach and antifungal prophylaxis of patients with risk factors will likely enhance the management of COVID-19 patients. | 2020-08-30 |
| 32861084 | The events leading up to his COVID-19 diagnosis highlight the gaps of the international screening processes at the global border entry and the potential consequences of community chain transmission through imported COVID-19 cases. | 2020-08-30 |
| 32861174 | Especially in the areas with high disease burden, chest imaging plays a crucial role to speed up the diagnostic process and to aid the patient management. […] The purpose of this comprehensive review is to understand the diagnostic capabilities and limitations of chest X-ray (CXR) and high-resolution computed tomography (HRCT) in defining the common imaging features of COVID-19 pneumonia and correlating them with the underlying pathogenic mechanisms. […] The evolution of lung abnormalities over time, the uncommon findings, the possible complications, and the main differential diagnosis occurring in the pandemic phase of SARS-CoV-2 infection are also discussed. | 2020-08-30 |
| 32861584 | Coronavirus disease 2019 (COVID-19) diagnosis was confirmed by a SARS-CoV-2 reverse transcriptase polymerase chain reaction (PCR) on nasal swab. | 2020-08-31 |
| 32861692 | However, the unique aspects of COVID-19 confound both the diagnosis and treatment of PE, and therefore require modification of established algorithms. […] Important considerations include adjustment of diagnostic modalities, incorporation of the prothrombotic contribution of COVID-19, management of two critical cardiorespiratory illnesses in the same patient, and protecting patients and health-care workers while providing optimal care. […] This position paper from the PERT Consortium specifically addresses issues related to the diagnosis and management of PE in patients with COVID-19. | 2020-08-31 |
| 32861823 | Education and alerts are required for clinical teams to establish an early diagnosis and prompt treatment. | 2020-08-31 |
| 32861829 | This study allows comparison with mass-produced masks under consistent test conditions while employing several well-established techniques. | 2020-08-31 |
| 32861884 | The aim of this review was to summarise the published cases of myocarditis and describe their presentations, diagnostic processes, clinical characteristics and outcomes. […] CMR established the diagnosis in 10 patients, with features of cardiac oedema and cardiac injury. | 2020-08-31 |
| 32862058 | Overall this study provides an important basis for the ongoing evaluation of SARS-CoV-2 physiology in pregnancy and highlights the importance of the placenta as a key source of primary human tissue for ongoing diagnostic and therapeutic research efforts to reduce the global burden of COVID-19. | 2020-08-31 |
| 32862216 | Here, we recommend management of patients with neurological diseases and especially dementia and movement disorders, who are referred for neuroimaging with nuclear medicine techniques. | 2020-08-31 |
| 32862396 | This condition is due to the establishment of an “Internet +” diagnosis and treatment model based on online medical application (APP), telemedicine, WeChat service, and consultation hotline in Taizhou. | 2020-08-31 |
| 32862406 | We aimed to assess the diagnostic performance of CT in patients with a negative first RT-PCR testing and to identify typical features of COVID-19 pneumonia that can guide diagnosis in this case. […] Negative RT-PCR test but positive CT features should be highly suggestive of COVID-19 in a cluster or community transmission scenarios, and the second RT-PCR test should be promptly requested to confirm the final diagnosis. | 2020-08-31 |
| 32862474 | Critical care ultrasonography is vital because it provides real time information for diagnosis and treatment. | 2020-08-31 |
| 32862842 | Therefore, the need for sensitive, selective, and rapid diagnostic devices plays a vital role in selecting appropriate treatments and to prevent the epidemics. […] Moreover, this review discusses different fabrication techniques, detection principles, and applications of various virus biosensors. | 2020-09-01 |
| 32863191 | We highlighted the need for auscultating the chest for early diagnosis. | 2020-09-01 |
| 32863199 | Serum KL-6 levels were significantly higher in the severe group than in the non-severe group both at diagnosis (median, 338 U/mL) and at peak levels within one week after diagnosis (median, 781 U/mL) (both p < 0.001). | 2020-09-01 |
| 32863339 | In the summer during the COVID-19 pandemic, a differential diagnosis between the two conditions is important. | 2020-09-01 |
| 32863359 | Of these, the diagnosis of coronavirus disease (COVID-19) was confirmed in four patients with typical chest computed tomography (CT) findings, and one patient without typical CT findings in whom the test result was strongly suspected to be false positive. | 2020-09-01 |
| 32863388 | The diagnosis of anxiety and depression was made by the HAD (Hospital Anxiety and Depression scale). | 2020-09-01 |
| 32863536 | The governing elite deployed state power in ways that used this conjuncture to continue previous patterns of domination that have continuously expanded surveillance, extending techniques for the extraction of vital data for commercial and political purposes. | 2020-09-01 |
| 32863557 | In order to propose the best diagnosis, the use of direct diagnosis, by reverse transcriptase-polymerase chain reaction, or indirect diagnosis, by serology, needs to be clarified. | 2020-09-01 |
| 32863593 | The long-term effects of healthcare reshuffling in the “COVID-19 era” imply a delay in the diagnosis and treatment of skin cancer and cancellation of many reconstructive procedures. | 2020-09-01 |
| 32863618 | The development of novel digital auscultation techniques has become highly significant in the context of the outburst of the pandemic COVID 19. | 2020-09-01 |
| 32863810 | This review explores the innovations in electrochemical biosensing based on the various electroanalytical techniques including voltammetry, impedance, amperometry and potentiometry and discusses their potential in diagnosis of emerging and re-emerging infectious diseases (Re-EIDs), which are potential pandemic threats. | 2020-09-01 |
| 32864068 | Effective management of conjunctivitis includes timely diagnosis, appropriate differentiation of the various etiologies, and appropriate treatment. | 2020-09-01 |
| 32864104 | Methods: We used systematic searching, coding and synthesis techniques to develop a systems-based logic model. | 2020-09-01 |
| 32864178 | The treatment plan complies with three principles, namely, multidisciplinary management of patients, individualized diagnosis and treatment plans, and timely monitoring and intervention of disease. […] According to a patient’s specific disease condition, an individualized diagnosis and treatment plan is formulated (one plan for one patient). | 2020-09-01 |
| 32864224 | However, this is a non-trivial endeavor due to the complexity of real world conditions and limits to the availability of diagnostic tests, which necessitate a bias in testing favoring symptomatic individuals. | 2020-09-01 |
| 32864225 | Our case highlights the inaccuracy of using clinical diagnosis for surgical abdomen in the COVID-19 era. | 2020-09-01 |
| 32864302 | The study was community based cross sectional design conducted from March 10-Apr 10, 2020, using a multi stage sampling techniques. | 2020-09-01 |
| 32864340 | Diagnostic work-up should be initiated as early as possible and should ideally include fungal cultures, galactomannan detection and Aspergillus PCR on tracheal aspirates or broncho-alveolar lavage fluid. […] Empiric systemic antifungal therapy may be justified in selected cases, pending diagnostic work up results. […] Large, multi-center studies are required to further understand the pathogenesis of invasive aspergillosis in COVID-19, and the optimal diagnostic and treatment strategies. | 2020-09-01 |
| 32864444 | Diagnostic laryngoscopy was successfully performed in a negative pressure microenvironment created to limit dispersion of aerosols. | 2020-09-01 |
| 32864456 | In conclusion, thrombocyte count is key in both diagnosis and prognosis. […] And although lymphocyte, D-dimer and CRP levels did not demonstrate diagnostic value, all indicate severity of COVID-19. | 2020-09-01 |
| 32864472 | Laboratory tests at the time of diagnosis showed hospital-level differences equivalent to country-level variation across the consortium partners. | 2020-09-01 |
| 32864514 | We analysed associations between features at diagnosis and the first 3 consecutive haemodialysis sessions in patients who required future hospital admission, and those who had died at 28 days. […] No patients received antiviral medication or hydroxychloroquine. 21 patients (20%) were admitted at COVID-19 diagnosis. 29 of 85 patients (34%) were admitted after initial outpatient management. 16 patients (15%) died. | 2020-09-01 |
| 32864520 | This case illustrates that SARS-CoV-2 infection must be considered in the differential diagnosis of patients presenting with signs or symptoms of coagulopathy, even in the absence of respiratory symptoms. | 2020-09-01 |
| 32864547 | After observing variability in testing techniques, we otolaryngologists at a tertiary medical center initiated and evaluated the impact of nasopharyngeal and oropharyngeal swabbing training, including video instruction, to standardize sampling techniques and ensure high-quality specimens. | 2020-09-01 |
| 32864570 | To determine changes in clinical and radiologic findings associated with Coronavirus disease 2019 (COVID-19) from diagnosis to recovery, we retrospectively reviewed the diagnosis and treatment records of the first patient cured of COVID-19 in Guangzhou. […] This study provides some new insights into the formulation of a timely and effective diagnostic and therapeutic strategy to cure patients with COVID-19. | 2020-09-01 |
| 32864576 | The neuroimaging is essential to diagnosis, showing white matter vasogenic edema in posterior areas. | 2020-09-01 |
| 32864577 | Visual exploratory data analysis (V-EDA) techniques have been followed in this research to understand the epidemiological characteristics of COVID-19 outbreak in different districts of Bangladesh between 8 March 2020 and 13 August 2020 and these findings were compared with those of other countries. | 2020-09-01 |
| 32864639 | Although diagnostic laboratory testing is utilized ubiquitously by physicians and encountered regularly by individuals receiving medical care, several aspects of test interpretation are incompletely understood by medical communities and the general population, creating a significant challenge in minimizing the damage caused by disease spread through informed decision making and proper testing utilization. | 2020-09-01 |
| 32864735 | During this period of crisis, researchers over the world have ramped their efforts to constrain the disease in all possible ways, whether it is vaccination, therapy or diagnosis. […] An early and efficient diagnosis could leverage the outcome until a successful vaccine is developed. […] Both in-house and commercial kits are the preferred molecular tests being used worldwide in the COVID-19 diagnosis. […] The objective of this review is to share the diagnostic performance of various immunological assays reported so far in severe acute respiratory syndrome coronavirus 2 case detection. […] We consolidate the studies (published and preprints) related to serological tests such as chemiluminescence, enzyme-linked and lateral flow-based point-of-care tests in COVID-19 diagnosis and update the current scenario. | 2020-09-01 |
| 32864911 | It is suggested that mandatory diagnostic testing prior to release and the symptom-based surveillance after the 14-day quarantine may help control delayed or asymptomatic COVID-19 cases. | 2020-09-01 |
| 32865095 | We found no consensus regarding the best diagnostic criteria for identifying a suspected case of COVID-19. | 2020-09-01 |
| 32865458 | The most widely used diagnostic technique for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is real-time reverse transcriptase-polymerase chain reaction (RT-PCR). […] A review was conceived to discuss advantages and limitations of the available diagnostic modalities for nonserologic diagnosis of SARS-CoV-2 based on RT-PCR; the article also proposes some practical suggestions to improve diagnostic reliability. […] Diagnostic accuracy of NPS and OPS is suboptimal and the risk of contaminated aerosol dispersal is not negligible. […] There is an urgent need for comparative trials to define the diagnostic modality of choice. | 2020-09-01 |
| 32865778 | The aim of this review was to collate and categorize the dermatologic findings reported in patients with COVID-19 and identify specific lesions that may facilitate diagnosis and prognostication. […] Vesicular rashes may suggest an initial diagnosis of COVID-19, acral lesions may be most appropriate for epidemiological uses, and vascular rashes may be a useful prognostic marker for severe disease. | 2020-09-01 |
| 32865940 | Cases now are defined by tests confirming that the person is shedding the SARS-CoV-2 (ie, a laboratory vs. a symptomatic diagnosis). | 2020-09-01 |
| 32866264 | Through the coronavirus disease 2019 (COVID-19) pandemic, telemedicine became a necessary entry point into the process of diagnosis, triage and treatment. […] Electronic health record data of patients at New York University Langone Health between March 19th and April 30, 2020 were used to conduct descriptive and multilevel regression analyses with respect to visit type (telemedicine or in-person), suspected COVID diagnosis and COVID test results. | 2020-09-01 |
| 32866368 | We survey the current state-of-the-art antimicrobial functional finishes on fabrics to protect the wearer against viruses and bacteria and provide an overview of protective medical fabric manufacturing techniques, their supply chains, and the environmental impacts of current single-use synthetic fiber-based protective clothing. | 2020-09-01 |
| 32866435 | This case emphasize that, in pandemic era, having a diagnostic of one infection does not rule out the possibility of having another infection concomitantly. […] In addition, underscores the importance of an accurate and timely diagnosis to prevent the spread of COVID-19. | 2020-09-01 |
| 32866812 | A protocol for the identification of novel coronaviruses by viral metagenomic sequencing in diagnostic laboratories may contribute to pandemic preparedness. | 2020-09-01 |
| 32867105 | It also looks at the role of embitterment in the genesis of psychiatric disorders like depression, anxiety, and PTSD, while focusing on the nature and factors needed to make a diagnosis of Posttraumatic Embitterment Disorder. | 2020-09-02 |
| 32867108 | Nine soldiers had at least one positive COVID-19 diagnostic test result. | 2020-09-02 |
| 32867260 | Furthermore, regulatory agencies have addressed various approaches toward these products, whether they authorize claims mentioning a disease’s diagnosis, prevention, or treatment. | 2020-09-02 |
| 32867591 | The European Position Paper on Rhinosinusitis (EPOS) provides widely accepted diagnostic criteria, which include sinonasal symptoms, their duration, and imaging results. | 2020-09-02 |
| 32867849 | During late-May 2019, three cross-sectional surveys of primary school children for schistosomiasis were conducted using a combination of rapid diagnostic tests, parasitological examinations and applied morbidity-markers; 1) schistosomiasis dynamics were assessed at Samama (n = 80) and Mchoka (n = 80) schools, where Schistosoma mansoni was first reported, 2) occurrence of S. mansoni was investigated at two non-sampled schools, Mangochi Orphan Education and Training (MOET) (n = 60) and Koche (n = 60) schools, where B. pfeifferi was nearby, and 3) rapid mapping of schistosomiasis, and B. pfeifferi, conducted across a further 8 shoreline schools (n = 240). | 2020-09-02 |
| 32868193 | Patients should have chest CT performed if suspected for early diagnosis and therapeutic intervention, resulting in a favorable outcome and prevention of secondary nosocomial transmitted infection. | 2020-09-02 |
| 32868442 | As assay protocols and primer sequences become widely known, many laboratories perform diagnostic tests using methods such as RT-PCR or reverse transcription loop mediated isothermal amplification (RT-LAMP). […] This work demonstrates an alternative pathway for SARS-CoV-2 diagnostics that does not require conventional laboratory infrastructure, in settings where diagnosis is required at the point of sample collection. | 2020-09-02 |
| 32868736 | However, despite efforts to prevent pressure injuries, we found our patients in the ICU with the diagnosis of COVID-19 went on to develop significant pressure and mucosal injuries. | 2020-09-02 |
| 32868801 | This technique may provide new opportunities in diagnosis and research of COVID-19. […] A clinical perspective of these features on drug molecules can broaden the application of hyperpolarization techniques for therapeutic studies. | 2020-09-02 |
| 32868966 | However, the limited availability of expert radiologists to interpret the CXR images and subtle appearance of disease radiographic responses remains the biggest bottlenecks in manual diagnosis. | 2020-09-02 |
| 32868971 | Corona virus disease 2019 (COVID-19) is a clear example of how a virus can have a global impact in the society and has demonstrated the limitations of detection and diagnostic capabilities globally. | 2020-09-02 |
| 32868974 | This case shows that PE is a differential diagnosis in non-hospitalized symptomatic Covid-19 with persisting breathing problems. | 2020-09-02 |
| 32869227 | Finally, suspected COVID-19 diagnosis was verified serologically. […] In case of a high degree of clinical suspicion in combination with typical findings of thoracic imaging, the suspected diagnosis COVID-19 disease should be maintained even in case of multiple negative SARS-CoV-2-PCR. […] Seroconversion occurs a few days to 2 weeks after the onset of symptoms and can be used to confirm the diagnosis. | 2020-09-02 |
| 32869728 | The case refers to a 51-year-old symptomatic man with a new SARS-CoV-2 RNA positive nasopharyngeal swab after two negative ones and the lack of significant development of antibody response measured by different diagnostic serological test. […] Our case underlines that a discrepancy between clinical course of SARS-CoV-2 infection and results from diagnostic tests may exist. | 2020-09-02 |
| 32869938 | The total number and diagnosis of patients, who attended a tertiary care hospital for the dermatology outpatient clinic between 1 April 2020 and 31 May 2020, were included in this study. | 2020-09-02 |
| 32870139 | Background The role and performance of chest CT in the diagnosis of the coronavirus disease 2019 (COVID-19) pandemic remains under active investigation. […] Purpose To evaluate the French national experience using Chest CT for COVID-19, results of chest CT and RT-PCR were compared together and with the final discharge diagnosis used as reference standard. […] The final discharge diagnosis, based on multiparametric items, was recorded. […] Using final diagnosis as the reference, 2564 of the 4824 patients were positive for COVID-19 (53%). […] Conclusion Use of chest CT for the initial diagnosis and triage of suspected COVID-19 patients was successful. | 2020-09-02 |
| 32870239 | On bus 2, 24 of the 68 individuals (35.3% [including the index patient]) received a diagnosis of COVID-19 after the event. […] Among the other 172 individuals at the worship event, 7 (4.1%) subsequently received a COVID-19 diagnosis. | 2020-09-02 |
| 32870351 | Taken together, the combined overview of two of the most innovative and exciting developments in the immunoinflammatory field provides new insight into high-throughput construction of ultrasensitive cytokine and virion liquid chips for HTS of anti-inflammatory drugs or clinical diagnosis and treatment of inflammatory diseases including infectious diseases, acute or chronic inflammation (acute gouty arthritis or rheumatoid arthritis), cardiovascular disease, atheromatosis, diabetes, obesity, tissue injury and tumors. | 2020-09-02 |
| 32870517 | This future will bring many clinicians to one patient, connect individual experts to countless patients, use widely available devices to facilitate diagnosis, and apply novel technologies to measure the disease in new ways. | 2020-09-02 |
| 32870641 | Both explanations have major implications for infectivity, diagnosis, and management of the COVID-19 pandemic. | 2020-09-02 |
| 32870768 | Many of the techniques used to encourage audience participation in person can be adapted for use in online presentations (eg, the use of features such as chat, hand raising, polling, and question-and-answer sessions). | 2020-09-02 |
| 32870978 | Among RT-PCR positive HCW, 40% (95%CI;17%-65%) did not show symptoms at the time of diagnosis. | 2020-09-02 |
| 32871063 | We tested 2102 samples collected from 1237 persons up to 4 months after diagnosis by a quantitative polymerase-chain-reaction (qPCR) assay. […] Of the 1797 persons who had recovered from SARS-CoV-2 infection, 1107 of the 1215 who were tested (91.1%) were seropositive; antiviral antibody titers assayed by two pan-Ig assays increased during 2 months after diagnosis by qPCR and remained on a plateau for the remainder of the study. […] Our results indicate that antiviral antibodies against SARS-CoV-2 did not decline within 4 months after diagnosis. | 2020-09-02 |
| 32871264 | Diagnostic effectiveness (also called overall diagnostic accuracy) and reliability of a telehealth clinical examination versus a traditional shoulder clinical examination (SCE) has not been established. […] Our objective is to compare the diagnostic effectiveness of a telehealth shoulder examination against a SCE for rotator cuff tear (RCT), using magnetic resonance imaging (MRI) as a reference standard; secondary objectives included assessing agreement between test platforms and validity of individualized tests. […] We hypothesize that tests provided in a telehealth platform would not have inferior diagnostic effectiveness to a SCE. […] Two clinicians selected movement, strength and special tests for the SCE that are associated with diagnosis of RCT and identified similar tests to replicate for a simulated telehealth-based examination (STE). […] We calculated diagnostic effectiveness, which provides values from 0% to 100% as well as agreement statistics (Kappa) between tests by assessment platform, and sensitivity, specificity, and likelihood ratios for individual tests in both SCE and STE. […] We compared diagnostic effectiveness (overall) of SCE and STE with a Mann Whitney U. […] Diagnostic effectiveness of stand-alone tests were poor regardless of the group, with the exception of a few tests with high specificity. […] There was no significant difference between the overall diagnostic effectiveness of the STE and the SCE (p=0.98). | 2020-09-02 |
| 32871294 | Using the synthetic throat images, the deep learning model demonstrated a significant improvement in the accuracy of the pharyngitis diagnosis. […] The deep learning model for smartphone-based pharyngitis screening allows fast identification of severe pharyngitis with a potential of the timely diagnosis of pharyngitis. […] In the recent pandemic of COVID-19, this framework will help patients with upper respiratory symptoms to improve convenience in diagnosis and reduce transmission. | 2020-09-02 |
| 32871594 | Collected data included patient characteristics, clinical features at diagnosis, laboratory data, treatments and outcomes. […] Asthenia (77%), diarrhoea (34%) and anorexia (32%) were frequent at diagnosis. […] The delay between the onset of symptoms and diagnosis, death or complete recovery was 2 (0-5), 7 (4-11) and 32 (26.5-35) days, respectively. […] The median C-reactive protein (CRP) and lymphocyte count at diagnosis was 55 mg/L (IQR 25-106) and 690 Ly/µL (IQR 450-960), respectively. […] The case fatality rate was 24% and determinants associated with the risk of death were body temperature {hazard ratio [HR] 1.96 [95% confidence interval (CI) 1.11-3.44]; P = 0.02} and CRP at diagnosis [HR 1.01 (95% CI 1.005-1.017); P < 0.0001]. | 2020-09-02 |
| 32871851 | Considering three different scenarios with respect to the lockdown’s impact on breast cancer screening, we estimate that approximately 10,000 patients could have a missed diagnosis during these 3 months. […] Considering a 6-month period, as suggested by the Imperial college model, the number of patients who will not receive a diagnosis will rise to 16,000. […] Breast cancer screening should be resumed as soon as possible in order to avoid further breast cancer missed diagnosis and reduce the impact of delayed diagnosis. | 2020-09-03 |
| 32871857 | This was in part due to the formation of a dedicated surgical airway team, use of standardized procedural techniques and personal protective equipment (PPE), and construction of a negative pressure operating room within the COVID-19 isolation ward on the ship. | 2020-09-03 |
| 32871887 | The objective of this study was to investigate the risk factors for in-hospital mortality in patients with COVID-19, so as to provide a reference for the early diagnosis and treatment.This study retrospectively enrolled 118 patients diagnosed with COVID-19, who were admitted to Eastern District of Renmin Hospital of Wuhan University from February 04, 2020 to March 04, 2020. […] The AUC of combined diagnosis of these aforementioned factors were 0.992 (95% CI 0.981-1.000). | 2020-09-03 |
| 32871990 | As a result, diagnosis in many children is likely to be missed. | 2020-09-03 |
| 32872009 | By using various manual techniques at specified locations on the surface of the body, pediatric massage manipulation can unblock meridians, promote the circulation of qi and blood and strengthen resistance to pathogens. | 2020-09-03 |
| 32872154 | Relaxation techniques should be integrated into the daily routine to reduce stress levels. | 2020-09-03 |
| 32872469 | More frequent detections of the novel viruses by PCR than by mNGS on the same samples suggests that PCR remains the most sensitive diagnostic test for viruses whose genomes are known. | 2020-09-03 |
| 32872607 | The aim of this work was to develop a risk tool to identify GU cancer patients at risk of diagnosis, hospitalization, intubation, and mortality from COVID-19. […] The risk tool for predicting a diagnosis of SARS-CoV-2 had an AUC of 0.83, predicting hospitalization for management of COVID-19 had an AUC of 0.95, predicting patients requiring intubation had an AUC of 0.97, and for predicting COVID-19-related death, the risk tool had an AUC of 0.79. | 2020-09-03 |
| 32872736 | Subgroup analysis for the major confounders, age and region of diagnosis, resulted in OR and 95% CI of 0.912 (0.751-1.108) and 0.942 (0.791-1.121), respectively. | 2020-09-03 |
| 32872902 | Two experiments to measure the size of microscopic dielectric spherical particles immersed in purified water with spheres of a nominal diameter 5.2 ± 0.15 μm have been carried out in order to revisit Mie scattering techniques. […] The technique we offer here is found to be useful to familiarize technicians who work in the areas of applied optics, such as chemistry, electronics, water contamination, and optical instruments with Mie scattering techniques, and who may not have a formal introduction to the electromagnetic theory. […] One specific area in which these techniques might be useful is the study of aerosols that may arise when naturally produced droplets from humans, such as those produced by coughing, sneezing, talking, and breathing, are present, as it happens in response to the Severe Acute Respiratory Syndrome Coronavirus 2, also known as SARS-CoV-2. | 2020-09-03 |
| 32873101 | To evaluate the accessibility of pregnant women to prenatal screening and diagnostic tests during the COVID-19 pandemic process and analyze the effect of the pandemic process on acceptance-rejection rates of fetal diagnostic procedures for high risk pregnancies. […] As part of this cross-sectional study, during the pandemic, between the dates of 11 March 2020-30 June 2020 at Karadeniz Technical University Faculty of Medicine Perinatology Clinic, fetal structural anomaly detected by ultrasonography or with increased risk in screening test in the first and second trimester of high risk pregnancies, who were therefore recommended a prenatal diagnosis test, were defined as the control group and retrospectively compared with high risk pregnancies of the same periods (11 March 2019-30 June 2019) in the previous year. […] When the total number of prenatal diagnostic procedures and the year each of the procedures performed are compared, a statistically significant difference was found between the study and control groups (p: .041 and p < .001, respectively). […] When evaluating the rates of performed prenatal diagnostic procedures during the first patient visit in comparison to years, a statistically significant difference was observed in the A/S group and in the total number of cases (p = .023, p < .001, respectively). […] Similarly, the rate of performed prenatal diagnostic procedure during the first patient visit and the patient’s city of residence was similarly statistically significant from year to year (p < .05). […] The decrease in number of prenatal diagnosis and screening tests during the COVID-19 pandemic draws attention. | 2020-09-03 |
| 32873103 | Adult patients with a confirmed diagnosis of COVID-19 admitted to one of the health system’s intensive care units and requiring mechanical ventilation between March 9, 2020 and April 1, 2020, were included in this observational cohort study. […] In our observational cohort study of 85 mechanically ventilated COVID-19 patients, age, and a diagnosis of a solid malignant tumor were associated with 30-day mortality. | 2020-09-03 |
| 32873344 | The global coronavirus disease 2019 (COVID-19) pandemic has necessitated rapid alterations to diagnostic pathways for head and neck cancer patients that aim to reduce risk to patients (exposure to the hospital environment) and staff (aerosol-generating procedures). […] Diagnostic outcomes were retrospectively evaluated for a series of patients undergoing transoral fine needle aspiration cytology of oral cavity and oropharyngeal lesions during the COVID-19 pandemic. […] In one case, excision biopsy of a lymphoproliferative lesion was required for final diagnosis. […] Transoral fine needle aspiration cytology can provide rapid diagnosis in patients with oral cavity and oropharyngeal lesions. […] Whilst limitations exist (including tolerability and lesion location), the technique offers significant advantages pertinent to the COVID-19 era, and could be employed in the future to obviate diagnostic surgery in selected patients. | 2020-09-03 |
| 32873584 | We evaluated the risk of droplet and contact contamination for health care workers using 3 intubation barrier techniques as part of a quality assurance study at our institution. […] Further study should be undertaken before implementing barrier techniques in practice. | 2020-09-03 |
| 32874430 | Since most COVID-19 infected cases were diagnosed with pneumonia and characteristic chest computed tomography (CT) scan patterns, radiological examinations have become an important tool in early diagnosis. […] Nowadays, CT findings combined with normal blood cells (WBCs), lymphopenia and a history of epidemiological exposure have been used as criteria for clinical diagnosis of COVID-19. […] It is noteworthy that reverse transcription polymerase chain reaction (RT-PCR) test is still gold standard for the diagnosis. […] This review focuses on role of chest CT in the clinical evaluation of disease progression and more accurate diagnosis. | 2020-09-03 |
| 32874484 | To determine the challenges in diagnosis, monitoring, support provision in the management of inflammatory bowel disease (IBD) patients and explore the adaptations of IBD services. | 2020-09-03 |
| 32874594 | The coronavirus disease 2019 (COVID-19) pandemic is redefining the world we live in, and scientists are struggling to find the best severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic tool. […] A bronchoscopy was then performed, and RT-PCR testing on bronchoalveolar lavage samples yielded positive results, confirming the diagnosis of COVID-19 pneumonia. | 2020-09-03 |
| 32874972 | The reference standard for diagnosis of severe acute respiratory syndrome coronavirus 2 infection is real time reverse-transcription polymerase chain reaction test applied on respiratory tract specimens. | 2020-09-03 |
| 32874986 | COVID-19 diagnosis was confirmed based on blood cell counts, chest computed tomography (CT) imaging, and nuclei acid test results. | 2020-09-03 |
| 32875391 | Fifty-eight (37.4%) patients had received a clinical diagnosis of viral pneumonia with ground glass findings in tomography. | 2020-09-03 |
| 32875524 | Hence, knowledge about the diagnosis of COVID-19 is important to gastroenterologists as well. […] The right sample at the right time from the right anatomical site with the proper precautions is crucial in prompt and accurate diagnosis of COVID-19. […] In the direct test, real-time polymerase chain reaction (RT-PCR) assays are the molecular tests of choice for the diagnosis of COVID-19. […] In indirect testing, antigen-antibody-based techniques are recommended for surveillance for the disease, which may help to formulate the control measures. […] All the above tests are important not only for diagnosis but also for management strategy and prognosis. | 2020-09-03 |
| 32875578 | Encephalopathy caused by or arising from seizures, especially nonconvulsive seizures (NCS), often requires electroencephalography (EEG) monitoring for diagnosis. | 2020-09-03 |
| 32875662 | We designed an online laboratory activity using computational biology techniques to overcome this issue. | 2020-09-03 |
| 32875716 | The aim of this study was the systematic characterization of cases of SARS-CoV-2 infection among PLWHA, particularly focusing on age, clinical findings at diagnosis, radiological features, therapeutic management and clinical outcomes. | 2020-09-03 |
| 32875914 | Twenty-two percent (n = 45) of the surgeons had a score over 10 in the Patient Health Questionnaire (PHQ-9; scores higher than 10 needs referral to confirm depression diagnosis). | 2020-09-03 |
| 32875944 | Using a focused review of the literature and original analyses of the UK Biobank, we discuss how circadian biology may inform our diagnostic and therapeutic strategies in this pandemic. | 2020-09-03 |
| 32876011 | Recognizing paralytic ileus as a possible complication necessitates timely diagnosis and management. | 2020-09-03 |
| 32876207 | To determine the additional diagnostic performance of a rapid serological test for detection of IgM and IgG antibodies compared to the real-time polymerase chain reaction (RT-PCR) test; for detection of SARS-CoV-2. […] The additional diagnostic performance of rapid serological test was evaluated in comparison to molecular tests. […] The rapid serological test detected 21 cases that had been negative by the initial (RT-PCR), providing an additional diagnostic performance of 56.8% compared to the RT-PCR. […] The additional diagnostic performance was 50.0% during the first week, 70.0% during the second week and 50.0% during the third week of symptom onset. | 2020-09-03 |
| 32876225 | In efforts to reduce the spread of the disease, attention should be paid to the diagnosis and treatment of mental health issues. | 2020-09-03 |
| 32876241 | National governments and scientific field agents have been looking for evidence for the best practices of prevention and control of transmission, and care of infection and disease, including diagnosis, treatment, and health care measures. […] The large-scale testing strategy, aimed at early diagnosis, quarantine of the mild cases identified, as well as those of the contacts, and adequate care of severe cases, has been revised and indicated as one of the efficient pandemic control measures in several countries in the world. […] This paper aims to discuss the challenges of COVID-19 testing and diagnosis in Brazil. | 2020-09-03 |
| 32876296 | Therefore, pregnant women and neonates require special attention regarding the prevention, diagnosis and management of COVID-19. | 2020-09-03 |
| 32876299 | Although uncommon, pneumothorax should be listed as a differential diagnosis for COVID-19 patients with sudden respiratory decompensation. | 2020-09-03 |
| 32876316 | In the absence of a vaccine and specific therapies, disease control and promotion of patient health are strongly dependent on a rapid and accurate diagnosis. […] This review describes the main laboratory approaches to making a diagnosis of COVID-19 and identifying those previously infected with SARS-CoV-2. | 2020-09-03 |
| 32876320 | We reported the diagnosis of a child who tested positive for COVID-19 with abdominal pain/diarrhea and tracked his family cluster. | 2020-09-03 |
| 32876570 | The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of chest CT were calculated for the diagnosis of COVID-19, using RT-PCR as reference. […] Chest CT has high sensitivity and low specificity in the diagnosis of COVID-19. | 2020-09-03 |
| 32876571 | We aimed to evaluate the diagnostic performance of low-dose chest computed tomography (CT) in patients under investigation for coronavirus disease 2019 (COVID-19). […] The diagnostic performance of CT was calculated using rRT-PCR as a reference. […] Clinical and laboratory data, CT characteristics, and lesion distribution were assessed for patients with a confirmed diagnosis via rRT-PCR. | 2020-09-03 |
| 32877391 | Patients with heart failure and COVID-19 are a diagnostic dilemma because the signs of acute heart failure could be masked. | 2020-09-03 |
| 32877490 | The Covid-19 pandemic brought several challenges to the healthcare system: diagnosis, treatment and measures to prevent the spread of the disease. […] With the greater availability and variety of diagnostic tests, it is essential to properly interpret them. […] This paper intends to help dialysis units concerning the use of clinical criteria and diagnostic tests for decision making regarding the discontinuation of isolation of patients with suspected or confirmed Covid-19, as well as the return to work activities for employees with suspected or confirmed Covid-19. | 2020-09-03 |
| 32877499 | Some of them: - a Shared decision making, which enables the patient and family to participate as facilitators in the systematization of the team’s reasoning, in addition to respecting the principle of autonomy; - Symptom Management: which should be a priority to ensure relief of suffering even in times of social isolation; - Communication skills: making it possible to alleviate suffering in announcing bad news or complex decisions through communication techniques;; - Bereavement assistance: which in acute situations such as the pandemic, causing unexpected losses, the importance of sympathy from healthcare professionals becomes even greater. | 2020-09-03 |
| 32877507 | Infertility diagnosis and treatment frequently result in significant psychological distress. | 2020-09-03 |
| 32878025 | In these days of 2020, tests for the diagnosis of SARS-CoV-2, and their use in the context of health surveillance of workers, are becoming popular. […] The aim of this viewpoint paper is to make employers, workers, occupational physicians, and public health specialists think about the limits of diagnostic tests currently available, and the possible implication related to the erroneous and incautious assignment of “immunity passports” or “risk-free certificates” to workers during screening campaigns in workplaces. | 2020-09-04 |
| 32878627 | We calculated case fatality rates by dividing the death number of a specific day by the number of patients with confirmed COVID-19 infection observed 14 days before and normalized by a ρ factor which takes into account the diagnostic PCR testing capability of each Country and the number of positive cases detected. […] Strict lockdown strategies together with a wide diagnostic PCR testing of the population were correlated with a relevant decline of the case fatality rate in different Countries. | 2020-09-04 |
| 32878641 | In this review article, we describe the underlying molecular organization and phylogenetic analysis of the coronaviruses, including the SARS-CoV-2, and recent advances in diagnosis and vaccine development in brief and focusing mainly on developing potential therapeutic options that can be explored to manage this pandemic virus infection, which would help in valid countering of COVID-19. | 2020-09-04 |
| 32878678 | This paper examines what is required to make a diagnosis of a depressive or anxiety disorder and how this may differ from fleeting symptomatology in response to specific situations or stimuli. | 2020-09-04 |
| 32878835 | This case highlights the need to have a low index of suspicion in the diagnosis of COVID-19 and the need to be vigilant in use of personal protective equipment, even in paediatric patients with subtle symptoms. | 2020-09-04 |
| 32878840 | We discuss the differential diagnosis of these findings, and the possible mechanisms of hepatic injury in COVID-19. | 2020-09-04 |
| 32878931 | For example, defining the early evolutionary patterns of humoral immunity to SARS-CoV-2, and whether prevalent coronaviruses or other common infections influence the evolution of immunity, remains poorly understood but could inform diagnostic and vaccine development. […] These data suggest that preexisting receptor binding domain-specific immunity does not influence or bias the evolution of immunity to SARS-CoV-2 and should have negligible influence on shaping diagnostic or vaccine-induced immunity. | 2020-09-04 |
| 32878994 | In this registry, key clinical and epidemiological parameters-for example, diagnosis of IRD, antirheumatic therapies, comorbidities and course of the infection-are documented. | 2020-09-04 |
| 32879082 | The course of the disease was long, and the time from symptom onset to the second severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid negative transformation was (17.22±6.34) days.There were no significant differences in the incubation period (t=-0.453, P>0.05), the complicates (χ2=0.042, P>0.05), and the time from symptom onset to diagnosis (t=-1.330, P>0.05) in patients between the non-severe group and the severe group. | 2020-09-04 |
| 32879101 | To explore the significance of coagulation and immune function indicators in clinical diagnosis and treatment of coronavirus disease 2019 (COVID-19). […] There are some abnormalities in coagulation and immune function in patients with COVID-19, which possess significance for clinical diagnosis and treatment of the disease. | 2020-09-04 |
| 32879103 | According to the “Program for the diagnosis and treatment of novel coronavirus (COVID-19) infected pneumonia (Trial version 7)” issued by the General Office of National Health Committee and Office of State Administration of Traditional Chinese Medicine as the diagnostic and typing criteria. | 2020-09-04 |
| 32879105 | Therefore, this review combines the existing research results with clinic experience of diagnosis and treatment for senile infectious diseases, summarizes the clinical characteristics and puts forward the prevention strategies of elderly COVID-19 patients, which provide evidence for effective prevention and treatment of COVID-19 in elderly patients, improvement of cure rate, and reduction of severe incidence rate and mortality. | 2020-09-04 |
| 32879113 | The National Health Commission has repeatedly revised the diagnosis and treatment guide for the coronavirus disease 2019. […] The latest guide is “New Coronary Virus-Infected Pneumonia Diagnosis and Treatment Plan (Seventh Trial Version)”(short for Seventh Version of Diagnosis and Treatment Plan). […] But the later 2 drugs aren’t mentioned in the Seventh Version of Diagnosis and Treatment Plan. | 2020-09-04 |
| 32879413 | IHC or in situ detection, as well as viable form (lung culture positive) was associated with the presence of hyaline membranes, usually within 2 weeks but up to 4 weeks after initial diagnosis. | 2020-09-04 |
| 32879801 | In light of the references published, this review demonstrates the biological features, spread, diagnosis and treatment of SARS-CoV-2 as a whole and aims to analyse the similarities and differences among SARS-CoV-2, SARS-CoV and MERS-CoV to provide new ideas and suggestions for prevention, diagnosis and clinical treatment. | 2020-09-04 |
| 32879862 | This single center retrospective study included 85 consecutive patients with a reverse transcriptase-polymerase chain reaction diagnosis of SARS-CoV-2 who underwent a pulmonary DECT angiography between March 16th 2020 and April 22th 2020. | 2020-09-04 |
| 32879987 | The current study aimed to design an ultra-low-dose CT examination protocol using a deep learning approach suitable for clinical diagnosis of COVID-19 patients. […] The results demonstrated that the deep learning algorithm is capable of predicting standard full-dose CT images with acceptable quality for the clinical diagnosis of COVID-19 positive patients with substantial radiation dose reduction. […] • Ultra-low-dose CT imaging of COVID-19 patients would result in the loss of critical information about lesion types, which could potentially affect clinical diagnosis. […] • Deep learning-based prediction of full-dose from ultra-low-dose CT images for the diagnosis of COVID-19 could reduce the radiation dose by up to 89%. | 2020-09-04 |
| 32880149 | This review analyzes literature on the development patterns of hydroxychloroquine retinopathy, basic principles of diagnosis and differentiation of this condition from other types of retinal pathology. | 2020-09-04 |
| 32880263 | The potential role for serological tests in the current COVID-19 pandemic has generated very considerable recent interest across many sectors worldwide, inter alia pathologists seeking additional weapons for their armoury of diagnostic tests; epidemiologists seeking tools to gain seroprevalence data that will inform improved models of the spread of disease; research scientists seeking tools to study the natural history of COVID-19 disease; vaccine developers seeking tools to assess vaccine efficacy in clinical trials; and companies and governments seeking tools to aid return-to-work decision-making. | 2020-09-04 |
| 32880264 | Antibody tests for the novel coronavirus, SARS-CoV2, have been developed both as rapid diagnostic assays and for high-throughput formal serology platforms. […] Although these tests may be a useful adjunct to a diagnostic strategy, they have a number of limitations. | 2020-09-04 |
| 32880337 | A compromise would require tissue biopsies and samples to be taken immediately after death to obtain diagnostic information, which could potentially guide care of future patients, or generate hypotheses for finding needed solutions. | 2020-09-04 |
| 32880381 | Participants described multiple symptoms during confinement. 1,050 diagnostic RT- PCR tests were performed, being positive in 323 cases, of which 33 were in asymptomatic people. […] Of the total number of professionals requiring isolation, 22.7% confirmed the diagnosis. | 2020-09-04 |
| 32880453 | As corona virus disease 2019 (COVID-19) is a rapidly growing public health crisis across the world, our knowledge of meaningful diagnostic tests and treatment for severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is still evolving. […] Hence, this perspective gives a brief of the existing knowledge, current challenges, and opportunities for MS-based techniques as a promising avenue in studying emerging pathogen outbreaks such as COVID-19. | 2020-09-04 |
| 32880556 | We describe the diagnostic and therapeutic challenges presented by this case. | 2020-09-04 |
| 32881133 | The diagnosis was made in patients with confirmed Covid-19 who presented with new-onset cognitive disturbances, central focal neurological signs or seizures. | 2020-09-04 |
| 32881209 | Here, we present a practical review of current literature and uses a case-based format to discuss the diagnostic approach and management of COVID-19-associated coagulopathy. | 2020-09-04 |
| 32881220 | The data related to clinical laboratory tests, outcomes, diagnosis, and drug treatments were collected. | 2020-09-04 |
| 32881359 | Routine treatment according to China’s Novel Coronavirus Pneumonia Diagnosis and Treatment Plan was performed in both groups, whereas patients in the BRH group were additionally given oral BRH (32 mg t.i.d.) for 14 consecutive days. | 2020-09-04 |
| 32881628 | This review provides current perspectives on morphology, genetic diversity, transmission characteristics, replication cycle, diagnostic approaches, epidemiological assessment, and prevention strategies against the SARS-CoV-2. | 2020-09-04 |
| 32881685 | Early diagnosis is critical for the prevention and control of the coronavirus disease 2019 (COVID-19). […] Whenever difficulties of remote manipulation and diagnosis occurred, the alternative examination was repeated by a specialist from another city, and in sequence, remote consultation was conducted immediately to meet the consensus. […] Remote consultation on the issue of manipulation practice, and the diagnosis in one case was conducted. […] The practice of teleultrasound protocol makes early diagnosis and repeated assessment available in the isolation ward. | 2020-09-04 |
| 32881850 | Among the 1,022 attendees (staff members and campers) from 41 states, one territory, and six international locations, 1,010 were tested before arrival; 12 attendees who had completed a period of isolation after receiving a diagnosis of COVID-19 2 months before arrival were not tested. […] Approximately 1 week after camp arrival, all 1,006 attendees without a previous diagnosis of COVID-19 were tested, and three asymptomatic cases were identified. | 2020-09-04 |
| 32881855 | Among the 194 seropositive participants, 56 (29%) reported no symptoms since February 1, 2020, 86 (44%) did not believe that they previously had COVID-19, and 133 (69%) did not report a previous COVID-19 diagnosis. | 2020-09-04 |
| 32881976 | We recruited 336 adult consecutive patients (male: 57.1%, mean age: 55.0±16.0 years) that were hospitalized with the diagnosis of COVID-19 in a tertiary care university hospital. | 2020-09-04 |
| 32882068 | According to the discrimination of other local and systemic conditions and the synchronous onset of oral and systemic symptoms, the diagnosis of oral lesions probably associated with COVID-19 was established. | 2020-09-04 |
| 32882074 | Detection, diagnosis, and treatment of hypertension require accurate blood pressure assessment. | 2020-09-04 |
| 32882184 | Familiarity with the cutaneous manifestations of COVID-19 may enable early diagnosis or help guide prognosis. | 2020-09-04 |
| 32882235 | This was a non-systematic review of the literature on the laboratory diagnosis of COVID-19. […] Searches in PubMed and Google Scholar for articles made available in 2020, using the terms “diagnosis” OR “diagnostic” OR “diagnostic tests” OR “tests” AND “COVID-19” OR “SARS-CoV-2” in the title. […] The gold standard for diagnosis is the identification of viral genome targets by real-time polymerase chain reaction (RT-PCR) in respiratory tract materials during the first week of symptoms. […] Imaging tests may be useful for diagnosis, especially when there is a compatible clinical picture, and other tests presented negative results or were unavailable. […] The diagnosis of COVID-19 should be based on clinical data, epidemiological history, tests for etiological diagnosis, and tests to support the diagnosis of the disease and/or its complications. […] New diagnostic methods with higher sensitivity and specificity, as well as faster results, are necessary. | 2020-09-04 |
| 32882315 | To assess the methodologies used in the estimation of diagnostic accuracy of SARS-CoV-2 real-time reverse transcription polymerase chain reaction (rRT-PCR) and other nucleic acid amplification tests (NAATs) and to evaluate the quality and reliability of the studies employing those methods. […] Studies were evaluated using elements of the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) guidelines. […] Employing standardized guidelines for study designs and statistical methods will improve the process for developing and validating rRT-PCR and NAAT for the diagnosis of COVID-19. | 2020-09-04 |
| 32883050 | However, this requires a reliable and clinically validated diagnostic platform for the sensitive and specific identification of SARS-CoV-2. […] To further enhance the assay performance and to remove any subjectivity associated with operator interpretation of results, we engineered a novel hand-held smart diagnostic device. […] The robust diagnostic device was further furnished with automated image acquisition and processing algorithms and the collated data was processed through artificial intelligence (AI) pipelines to further reduce the assay run time and the subjectivity of the colorimetric LAMP detection. | 2020-09-05 |
| 32883596 | LUS is able to significantly predict mortality in nursing home residents affected by COVID-19, suggesting that this simple tool can be routinely used in this setting instead of more invasive techniques available only in hospital. | 2020-09-05 |
| 32883705 | Almost all aspects of asthma care will be disrupted during the pandemic due not only to limits in face-to-face care but also to the fact that many of the diagnostic tools used in asthma are considered aerosol-generating procedures. | 2020-09-05 |
| 32883744 | The ongoing coronavirus disease 2019 (COVID-19) pandemic has resulted in shortages of nasopharyngeal swabs (NPS) and viral transport media, necessitating the search for alternate diagnostic specimens, such as saliva. […] Both specimens were tested with the CDC 2019 nCoV real-time RT-PCR diagnostic panel (4 February 2020 version), with the NPS result used as the reference standard. | 2020-09-05 |
| 32883809 | Our in-house kit compares favorably to a commercial product used for diagnostic testing. | 2020-09-05 |
| 32883951 | These results collectively suggest that SREBP-2 can serve as an indicator for severity diagnosis and therapeutic target for preventing cytokine storm and lung damage in severe COVID-19 patients. | 2020-09-05 |
| 32884213 | This work can be extrapolated for the detection of SARS-CoV-2 viral peptides in complex biological fluids for early diagnosis of COVID-19. | 2020-09-05 |
| 32884452 | The high rate of contagion for this virus and the highly nonspecific symptoms of the disease (Coronovirus disease 2019, (Covid-19)) that it causes, such as respiratory symptoms, cough, dyspnea, fever, and viral pneumonia, require the urgent establishment of precise and fast diagnostic tests to verify suspected cases, screen patients, and conduct virus surveillance. | 2020-09-05 |
| 32884871 | In addition, a framework for diagnosis and evaluation is provided that focuses on the pathway previously established for KD and MAS. | 2020-09-05 |
| 32884935 | The case highlights important points specific to a HD patient with a COVID-19 diagnosis, tailored interventions for each stage of the disease, and deisolation considerations in the recovery phase. | 2020-09-05 |
| 32884938 | During the coronavirus disease 2019 (COVID-19) outbreak in Germany, the diagnostic outcomes of critically ill patients admitted to the resuscitation room in the ED of our academic 754-bed hospital should be analyzed. […] Every patient with suspicion of SARS-CoV-2 infection received a pharyngeal swab for real-time polymerase chain reaction (rt-PCR), divided in the clinical subgroups of “highly suspicious for COVID-19” and “COVID-19 as differential diagnosis.” […] All respiratory and infectious symptoms were included as at least “differential diagnosis” as an expanded suspicion strategy. […] In 39 patients, COVID-19 was defined as differential diagnosis, and 3 were positive for SARS-CoV-2. […] We recommend an expanded suspicion strategy for COVID-19 due to unexpected diagnostic outcomes. | 2020-09-05 |
| 32885293 | The increasing COVID-19 widespread has created the necessity to assess the diagnostic accuracy of newly introduced (RT-PCR based) assays for SARS-CoV-2 RNA detection in respiratory tract samples. | 2020-09-05 |
| 32885345 | The results showed that the use of corticosteroids in the treatment of autoimmune diseases can make diagnosis and treatment of COVID-19 more challenging by preventing the fever. | 2020-09-05 |
| 32885616 | Other nanotechnological approaches are also decisive for the development of improved novel testing and diagnosis kits of coronavirus that are urgently required. | 2020-09-05 |
| 32885641 | The features of the examination of ENT, diagnostic and therapeutic procedures, including the use of silicone hydrotamps to stop the front and rear nose bleeds, developed in L.I. | 2020-09-05 |
| 32885776 | In the Amazon region of Loreto, where malaria cases are concentrated, COVID-19 has led to near-complete closure of the primary healthcare system, and diagnosis and treatment of acute febrile illnesses, including malaria, has plummeted. | 2020-09-05 |
| 32886159 | In 16/50 cases the diagnosis was based on typical CT criteria and on the typical COVID patient history. | 2020-09-05 |
| 32886210 | As surgeons in the anti-pandemic front line in China, we describe our experience with the diagnosis and treatment of COVID-19 in this country and how the work of surgeons is unfolding during the pandemic. | 2020-09-05 |
| 32886230 | According to anti-SARS-CoV-2 seroresponse in patients with COVID-19 from Croatia, we emphasised the issue of different serological tests and need for combining diagnostic methods for COVID-19 diagnosis. | 2020-09-05 |
| 32886249 | This is a retrospective multi-centre review of all patients admitted with a fractured NOF and a confirmed laboratory diagnosis of COVID-19 between 1 March and 26 April 2020. | 2020-09-05 |
| 32886298 | Over a seven-week period during the peak of the pandemic, prospective data were collected on MERIT activity, COVID-19 symptoms or diagnosis in the team members, and demographic, procedural, and clinical outcomes of patients. | 2020-09-05 |
| 32886428 | Bed-side echocardiographic revealed apical ballooning promptly supporting the diagnosis of TTS. | 2020-09-05 |
| 32886711 | Therefore, chest CT is a valuable tool for facilitating the diagnosis of COVID-19 and semiquantitative scoring of affected lung segments may further elucidate diagnosis and assessment of disease severity. | 2020-09-04 |
| 32886737 | This commentary proposes that diagnosis of early-onset neonatal COVID-19 infection should be limited to neonates with positive RT-PCR testing for SARS-CoV-2 within the initial 72 hours of life. | 2020-09-04 |
| 32886738 | To assess AMR identification using POCT, describe the United States AMR Diagnostic Challenge, and improve global standards of care for infectious diseases. […] Multidisciplinary healthcare personnel should learn the principles and practice of POCT, so they can meet needs with rapid diagnostic testing. | 2020-09-04 |
| 32886846 | Thorough screening of incoming patients, separation of diagnostic and treatment areas, regional management, hierarchical protection, disinfection protocols, and other measures were enforced to prevent virus transmission during endoscopic treatments. | 2020-09-04 |
| 32886922 | He presented later with pneumonia complicated by encephalopathy at days 14 and 15 from initial diagnosis, respectively. | 2020-09-04 |
| 32887482 | The developed samples were subjected to different characterization techniques such as SEM, FTIR, XRD, TGA, and ICP studies. | 2020-09-05 |
| 32887670 | Diagnosis and treatment guidelines for clinicians caring for patients are needed. […] In the early stage, we have issued “A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)”; now there are many direct evidences emerged and may change some of previous recommendations and it is ripe for develop an evidence-based guideline. […] The steering group members proposed 29 questions that are relevant to the management of COVID-19 covering the following areas: chemoprophylaxis, diagnosis, treatments, and discharge management. […] They covered topics of chemoprophylaxis (including agents and Traditional Chinese Medicine (TCM) agents), diagnosis (including clinical manifestations, reverse transcription-polymerase chain reaction (RT-PCR), respiratory tract specimens, IgM and IgG antibody tests, chest computed tomography, chest x-ray, and CT features of asymptomatic infections), treatments (including lopinavir-ritonavir, umifenovir, favipiravir, interferon, remdesivir, combination of antiviral drugs, hydroxychloroquine/chloroquine, interleukin-6 inhibitors, interleukin-1 inhibitors, glucocorticoid, qingfei paidu decoction, lianhua qingwen granules/capsules, convalescent plasma, lung transplantation, invasive or noninvasive ventilation, and extracorporeal membrane oxygenation (ECMO)), and discharge management (including discharge criteria and management plan in patients whose RT-PCR retesting shows SARS-CoV-2 positive after discharge). | 2020-09-05 |
| 32888168 | In order to contribute to the accumulation of knowledge in this area, we wanted to report a patient who was followed up with the diagnosis of COVID-19 and had been administered rituximab very recently due to a nephrotic syndrome caused by membranous nephropathy. | 2020-09-05 |
| 32888278 | In this review, we discuss the multi-organ pathophysiology of COVID-19 infection together with the treatment methods adopted and innovative diagnostic methods used. | 2020-09-05 |
| 32888840 | They were treated with HCQ for 14 days from the day of COVID-19 diagnosis. | 2020-09-05 |
| 32888901 | Information collected included the details of patient presentation, diagnosis, surgical procedure, and preoperative COVID-19 testing. | 2020-09-05 |
| 32888905 | The use of saliva as a diagnostic sample has several advantages. […] The aim of this study was to validate the use of saliva as a biological sample for diagnosis of COVID-19. | 2020-09-05 |
| 32889039 | Patients were 18 years and older; had a diagnosis of cancer; and were able to complete an online survey. | 2020-09-05 |
| 32889094 | This has motivated us to analyse 566 Indian SARS-CoV-2 sequences using multiple sequence alignment techniques viz. […] Thereafter, a consensus of these results, called as Consensus Multiple Sequence Alignment (CMSA), is prepared to have the final list of mutations so that the advantages of all four alignment techniques can be preserved. | 2020-09-05 |
| 32889405 | Instead, the current research is designed to predict the mortality rate of COVID-19 by Regression techniques in comparison to the models followed by five countries. | 2020-09-05 |
| 32889496 | During the first month of the SARS-CoV-2 outbreak, rapid development of PCR-based diagnostic tests became a global priority so that timely diagnosis, isolation, and contact tracing could minimize the advancing pandemic surge. […] Most early PCR diagnostic tests for SARS-CoV-2 remain inclusive of circulating viral diversity, but three assays with extensive mismatches highlight assay design challenges for novel pathogens and provide valuable lessons for PCR assay design during future outbreaks. | 2020-09-05 |
| 32889589 | Diagnostic tests confirmed severe acute respiratory syndrome coronavirus 2 infection. | 2020-09-05 |
| 32889759 | Behaviour change techniques (BCTs) were identified. | 2020-09-05 |
| 32889885 | Two surgeons alternated techniques, with 35 tracheostomies performed percutaneously and 32 via an open approach. | 2020-09-05 |
| 32889946 | Schools could use the following learning vehicles to help medical students explore these domains (1) asynchronous lectures covering telehealth history; (2) discussions on applications, ethics, safety, etiquette, and patient considerations; (3) faculty-supervised standardized patient telehealth encounters; and (4) hands-on diagnostic or therapeutic procedures using telehealth equipment. | 2020-09-05 |
| 32889955 | Challenges include the need to adapt the mental state examination to the telemedicine environment, the ability to perform detailed motor neurologic examinations in patients where motor features are important diagnostic considerations, appreciating nonverbal cues, managing acute safety and behavioral concerns in less controlled environments, and navigating intervention-based (neuromodulation) clinics requiring in-person contact. | 2020-09-05 |
| 32889972 | To determine the predictive computed tomography (CT) and clinical features for diagnosis of COVID-19 pneumonia. | 2020-09-05 |
| 32890032 | The summarized research in IIM is a step forward in being able to further define, and to distinguish disease activity from damage, in order to potentially aid future clinical diagnosis and management in this challenging disease. | 2020-09-05 |
| 32890723 | This case draws attention to the risk of false COVID-19 diagnosis when over-relying on CT scan imaging. | 2020-09-05 |
| 32890817 | The documents were reviewed by treating neurologist and MS nurses to be sure about diagnosis of COVID19. […] The positive polymerase chain reaction (PCR) result or compatible lung computed tomography (CT) scan was acceptable for COVID-19 diagnosis. 4647 patients answered the phone contact. | 2020-09-05 |
| 32890937 | We herein evaluated the analytical performances of the CE IVD-labeled Abbott SARS-CoV-2 IgG assay (Des Plaines, IL, USA) carried out with the automated Abbott Architect™ i2000 platform at Hôpital Européen Georges Pompidou, Paris, France, using serum sample panels obtained from health-workers with COVID-19 history confirmed by positive nucleic acid amplification-based diagnosis and from patients randomly selected for whom serum samples were collected before the COVID-19 epidemic. | 2020-09-05 |
| 32891146 | These outbreaks have tested the limits of healthcare systems and have posed serious questions about management using conventional therapies and diagnostic tools. […] In this regard, the use of nanotechnology offers new opportunities for the development of novel strategies in terms of prevention, diagnosis and treatment of COVID-19 and other viral infections. […] In this review, we discuss the use of nanotechnology for COVID-19 virus management by the development of nano-based materials, such as disinfectants, personal protective equipment, diagnostic systems and nanocarrier systems, for treatments and vaccine development, as well as the challenges and drawbacks that need addressing. | 2020-09-06 |
| 32891405 | Dyspnea on presentation, diabetes mellitus, and age 60 years or older were significantly associated with increased mortality (P ≤ .01) with a trend to higher mortality rate observed in those with hypertension and those receiving corticosteroids at the time of COVID-19 diagnosis. […] Older liver transplant patients with diabetes mellitus or hypertension, who are on maintenance corticosteroids, with a diagnosis of COVID-19 and describing breathlessness should be aggressively monitored for signs of deterioration because of the risk for mortality. | 2020-09-06 |
| 32891745 | However, the development of PE in COVID-19 patients is often complicated by such factors as delay of diagnosis, confounding medical conditions, and strict isolation precautions. | 2020-09-06 |
| 32891829 | The median time from hospital admission to COVID-19 diagnosis was 9.0 days (7.0-12.0) and was 6.0 days (4.0-7.0) from the day of surgery to COVID-19 diagnosis. | 2020-09-06 |
| 32891904 | This retrospective study included intubated patients admitted with the diagnosis of ARDS to the ICU at Munich university hospital. 22 patients had confirmed SARS-CoV2-infection (COVID-19 group), 14 patients had bacterial or other viral pneumonia (control group). | 2020-09-06 |
| 32891922 | To review a selective for a course in diagnostic pathology geared toward undergraduate medical students, including its design, technical implementation, instructor and student evaluations, and suggestions for options for further adjusting and optimizing the selective. […] None of the respondents had any previous instruction in diagnostic pathology. […] The selective demonstrated value for students and provided much-needed exposure to diagnostic pathology in clinical practice. | 2020-09-06 |
| 32891938 | Molecular assays based on reverse transcription-loop-mediated isothermal amplification (RT-LAMP) may be useful for rapid diagnosis of the severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) because of the easy performance and the option to bypass RNA extraction. […] However, when results of RT-PCR and RT-LAMP were combined diagnostic sensitivity was increased to 92-100 %. […] The variplex RT-LAMP may serve as a rapid test to be combined with a RT-PCR assay to increase the diagnostic accuracy in patients with suspected COVID-19 infection. | 2020-09-06 |
| 32892628 | Hence, the rational identification of biomarkers for diagnostic measures on the one hand, and antigenic targets for vaccine development on the other, are of utmost importance. […] This enabled for example the identification of discriminant/diagnostic epitopes in Zika or influenza and mapping epitope evolution in natural infections versus vaccinations. | 2020-09-07 |
| 32892980 | Globally, only 49% perform preoperative diagnostic tests for SARS-CoV-2, and 58.5% recognize there have been cases confirmed postoperatively after other surgeries, with worse surgical outcomes in 54%. | 2020-09-07 |
| 32893047 | We used standard qualitative analysis techniques, consisting of both inductive and deductive approaches, to identify and characterize themes. | 2020-09-07 |
| 32893398 | These risk factors may facilitate the early diagnosis of critical patients in clinical practice. | 2020-09-07 |
| 32893488 | Measurements of multiple biomolecules within the same biological sample are important for many clinical applications to enable accurate disease diagnosis or classification. | 2020-09-07 |
| 32893786 | These characteristics have potential value in differential diagnosis. | 2020-09-07 |
| 32893844 | Public health and diagnostic laboratories are facing huge sample loads for COVID-19 diagnosis by real-time reverse transcription-polymerase chain reaction (RT-PCR). […] Ten virus research and diagnostic laboratories (VRDLs) testing for COVID-19 by real-time RT-PCR participated in this evaluation. | 2020-09-07 |
| 32894024 | ARDS: acute respiratory distress syndrome; aOR: adjusted odds ratio; ALT: alanine transferase; ALIMA: Alliance for International Medical Action; AST: aspartate transaminase; BUN: blood urea nitrogen; CNS: central nervous system; CUBE: chambre d’urgence biosécurisée pour épidémie; COVID-19: coronavirus disease 2019; Ct: cycle threshold; DRC: Democratic Republic of Congo; ETC: ebola treatment centre; ETU: ebola treatment unit; EBOV: ebola virus; EVD: ebolavirus disease; FEAST: fluid expansion as supportive therapy; GP: glycoprotein; IV: intravenous; MEURI: monitored emergency use of unregistered interventions; NETEC: National Ebola Training and Education Centre; NP: nucleoprotein; ORS: oral rehydration solution; PALM: Pamoja Tulinde Maisha; PREVAIL: Partnership for Research on Ebola Virus in Liberia; PPE: personal protective equipment; PCR: polymerase chain reaction; PEP: post-exposure prophylaxis; RDTs: rapid diagnostic tests; RT: reverse transcriptase; RNA: ribonucleic acid; UNICEF: United Nations International Children’s Emergency Fund; USA: United States of America; WHO: World Health Organization. | 2020-09-07 |
| 32894436 | This article aims to describe the establishment of a COVID Recovery Service, a multidisciplinary service for comprehensive follow-up of patients with a hospital diagnosis of COVID-19 pneumonia. | 2020-09-07 |
| 32894583 | The diagnostic performance of LUS and chest CT was calculated with rRT-PCR as a reference. […] Positive and negative likelihood ratios measured the diagnostic accuracy. | 2020-09-07 |
| 32894621 | Lung ultrasound has become an important tool in diagnosis and follow-up of patient with COVID-19 infection.Here we review available, up to date literature on ultrasound use for COVID-19 suspected pediatric patients and contrast it to published findings in adult patients. | 2020-09-07 |
| 32894654 | The first diagnosis of COVID-19-compatible symptoms in the village was recorded on 3 March 2020, and the last known active case resolved on 5 June 2020. | 2020-09-07 |
| 32894686 | The estimates were robust to different modelling techniques and specifications. | 2020-09-07 |
| 32894753 | Using the OTA, 78/98 (80%) of initially positive SARS-CoV-2 IgG results were confirmed with a second-line test, while 11/42 (26%) of previously diagnosed COVID-19 patients had no detectable antibodies as long as 94 days post PCR diagnosis. | 2020-09-07 |
| 32894756 | Reverse transcription (RT)-PCR, the principal diagnostic method applied in the world-wide struggle against COVID-19, is capable of detecting a single molecule of a viral genome. | 2020-09-07 |
| 32894811 | The clinical features of the patients were analysed and kidney function values before Covid-19 diagnosis were compared with kidney function values after Covid-19 diagnosis. | 2020-09-07 |
| 32894853 | We retrospectively investigated patients with a confirmed diagnosis of COVID-19 but who did not show any symptoms. | 2020-09-07 |
| 32894969 | Our results demonstrated that this software could improve the diagnostic rate for not-well experienced physicians. | 2020-09-08 |
| 32894991 | The sub-speciality of neuroradiology, both diagnostic and neuro-intervention, forms a very important part of any radiology or ‘neuro-care’ set-up. | 2020-09-08 |
| 32895105 | Methods The clinical data,laboratory findings,and outcomes of 64 patients with severe COVID-19 treated with TCM and western medicine in Chongqing from January 20,2020, to March 11,2020 were retrospectively analyzed.Patients were divided into early intervention group[TCM was initiated within 3 days (including day 3) after the first diagnosis of severe type/critical type COVID-19]and late intervention group[TCM was initiated after 7 days (including day 7) after the first diagnosis of severe type /critical type COVID-19]. […] Conclusion Early TCM therapy within three days after a diagnosis of severe COVID-19 can shorten the length of hospital stay,duration of ICU stay,and time to negativity and decrease intubation rate. | 2020-09-08 |
| 32895122 | Since the outbreak of COVID-19 pandemic, the detection capability has been improving and the detection techniques have been evolving with innovations. qRT- PCR and mNGS, which represent the current mainstay diagnostic technologies, play key roles in disease diagnosis and monitoring of virus variation. […] The detection technologies based on serum and plasma IgM and IgG antibodies are important for auxiliary diagnosis. […] RT-LAMP is highly specific for a diagnostic purpose. […] These techniques all have great potential for future development and application for pathogen detection. […] In this review the authors summarize the basic rationales, technical characteristics and the current application of the SARS-CoV-2 detection techniques. | 2020-09-08 |
| 32895128 | The Diagnostic and Treatment Protocol for COVID-19 (Trial Version 6) in China recommends chloroquine phosphate for the first time as an anti-coronavirus trial drug. | 2020-09-08 |
| 32895161 | Ninety-three patients with confirmed diagnosis of COVID-19 admitted in Ezhou Central Hospital from February to April in 2020 were analyzed. […] Among them, 43 patients were selected from Intensive Care Unit (ICU) with the diagnosis of critical type of COVID-19, and 50 cases of common type were selected from the Department of Respiratory Medicine. | 2020-09-08 |
| 32895296 | Increasing age, receipt of antitumor treatment within 3 months before COVID-19 diagnosis, elevated WBC count and dNLR, and having dyspnea on admission were independent risk factors for mortality among patients with COVID-19 and solid tumors. | 2020-09-08 |
| 32895587 | However, the facility for RT-PCR test is limited, which causes early diagnosis of the disease difficult. | 2020-09-08 |
| 32895629 | Consequently, understanding the prevalence of pathogenic viruses in untreated/treated waters and their removal techniques has become the topical issue of the scientific community. | 2020-09-08 |
| 32895799 | Five typical surgical intervention techniques (mechanical stress with a passive instrument with and without suction, CO2 laser treatment, drilling and bipolar electrocoagulation) were examined and compared regarding resulting particle release. | 2020-09-08 |
| 32896175 | However, there are few reviews focusing on summary and comparison of diagnostic methods and complications induced by SARS-CoV-2 infection, which places a significant limit on the effective management. […] We searched PubMed using the terms ‘COVID-19 & diagnosis’ and ‘COVID-19 & complications’ and selected the most relevant articles. […] Here we summarize the diagnostic methods that are available in clinic and discuss their different characters. […] The comparison between different characters of the diagnostic methods and the summary of the symptoms, incidence, and clinical strategies of complications given in this review are not only significant for the optimal use of diagnostic methods, but also beneficial for the prevention and management of complications. | 2020-09-08 |
| 32896179 | This systematic review is focused on currently used diagnostic methods for COVID-19 detection and their future prospects. […] The search has identified the potential applications of nucleic acid technology, diagnostics radiology examinations, and in-vitro diagnostic kits in detection of COVID-19 infections. […] Despite having their own limitations of each technology, the emerging diagnostic technologies for COVID-19 detection along with undergoing clinical trials are summarized suggesting more collaborations and funding are required for fast track clinical trials. | 2020-09-08 |
| 32896705 | All patients tested positive for SARS-CoV-2 by PCR with a previous diagnosis of rheumatologic diseases were reviewed. | 2020-09-08 |
| 32896946 | Molecular testing turnaround time precludes having results at the point-of-care (POC) thereby exposing COVID-19/Non-COVID-19 patients while awaiting diagnosis. […] The primary endpoint was diagnostic performance of FebriDx to identify COVID-19 as a viral infection; secondary endpoint was SARS-CoV-2 molecular test diagnostic performance compared with the reference standard COVID-19 Case Definition (molecular or antibody detection of SARS-CoV-2). […] FebriDx was viral negative when the diagnosis was not COVID-19 and SARS-Cov-2 molecular test was negative (negative predictive value (NPV) 100% (13/13; 95%CI 71.7-100)) exceeding initial SARS-CoV-2 molecular test NPV 72.2% (13/19; 95%CI 46.4-89.3). […] The diagnostic specificity of FebriDx and initial SARS-CoV-2 molecular test was 100% (13/13; 95%CI 70-100 and 13/13; 95%CI 85.4-100, respectively). | 2020-09-08 |
| 32897080 | A coronavirus-focused METATRYP database identified potential SARS-CoV-2 peptide biomarkers and indicated very few shared tryptic peptides between SARS-CoV-2 and other disparate taxa analyzed, sharing <1% peptides with taxa outside of the betacoronavirus group, establishing that taxonomic specificity is achievable using tryptic peptide-based proteomic diagnostic approaches. | 2020-09-08 |
| 32897209 | To understand the distribution patterns and the factors influencing the interval between entry of mainland China and diagnosis in imported COVID-19 cases in Guangdong Province to provide evidence for formulating and implementing effective control measures. […] Descriptive statistical methods were used to analyze the distribution patterns of the interval between entry of mainland China and diagnosis of the imported cases, and multivariate logistic regression was used to analyze the factors influencing the interval. […] The average interval between entry of mainland China and diagnosis was 4.21 days with a median of 2 days. […] Multivariate logistic regression analysis showed that a negative result of the initial nucleic acid test (OR=5.205, 95% CI: 1.100-24.640, P=0.038) and interval between entry of mainland China and a positive diagnosis >2 days (OR=85.654, 95%CI: 24.569-298.615, P < 0.001) were risk factors for the finding delay. […] The results of initial nucleic acid detection and the interval between entry of mainland China and a positive diagnosis of COVID-19 are the major contributing factors of delayed case detection. | 2020-09-08 |
| 32897296 | Diagnosis of COVID-19 was determined by positive severe acute respiratory syndrome coronavirus 2 polymerase chain reaction nasopharyngeal swab result. […] Diagnostic-grade T1-weighted, T2-weighted, T2 fluid-attenuated inversion recovery, and diffusion-weighted imaging sequences were obtained for 37, 48, 45, and 32 patients, respectively. | 2020-09-08 |
| 32897374 | More patients hospitalized with COVID-19 than with seasonal influenza reported clinical symptoms at the time of diagnosis. | 2020-09-08 |
| 32897438 | Reference standard for the diagnosis of COVID-19 is a positive reverse transcription polymerase chain reaction (RT-PCR) test. | 2020-09-08 |
| 32897493 | With the increasing trend of using chest CT scans as an imaging tool to diagnose and monitor SAR-CoV-2, we emphasize that pattern recognition is the key, and this pictorial essay should serve as a guide to help establish correct diagnosis coupled with correct scanner parameters to reduce radiation dose without affecting imaging quality in this tragic pandemic the world is facing. | 2020-09-08 |
| 32898090 | After an evaluation of infectious causes, the diagnosis of MIS-C was made approximately 1 month after her initial symptoms. | 2020-09-08 |
| 32898153 | Since SARS-CoV-2-based disease (COVID-19) spreads as a pandemic, the necessity of a highly sensitive molecular diagnosis that can drastically reduce false negatives reverse transcription PCR (rtPCR) results, raises as a major clinical need. […] Thanks to a ddPCR-based assay, we achieved a rapid and accurate SARS-CoV-2 diagnosis in rtPCR-negative respiratory samples of individuals with COVID-19 suspect, allowing the rapid taking care and correct management of these patients. | 2020-09-08 |
| 32898340 | Finally, remaining challenges in COVID-19 diagnostic testing are discussed, including (a) the lack of universal standards for diagnostic testing; (b) the identification of appropriate sample collection site(s); (c) the difficulty in performing large population screening; and (d) the limited understanding of SARS-COV-2 viral invasion, replication, and transmission. | 2020-09-08 |
| 32898341 | The study included patients who were hospitalized with COVID-19 diagnosis and had cardiac biomarker assessments and simultaneous 12-lead surface ECGs. | 2020-09-08 |
| 32898813 | The currently active COVID-19 pandemic has increased, among others, public interest in the computational techniques enabling the study of disease-spreading processes. | 2020-09-08 |
| 32898875 | Sepsis accounts for mortality for almost 50% of global children under 5 years of age.Over the past 50 years, there have been many advances in the diagnosis, prevention, and treatment of neonatal infections. […] The diagnostic advances include better culture techniques that permit more rapid confirmation of the diagnosis, advent of polymerase chain reaction (PCR) to rapidly diagnose viral infections, use of biologic markers indicating evidence of infection, and a better understanding of immunoglobulin markers of infection. | 2020-09-08 |
| 32898993 | Knowledge regarding the detection, diagnosis, treatment, and follow-up of COVID-19-associated neurological damage is still limited. | 2020-09-09 |
| 32899333 | We assessed the sensitivity, specificity and positive and negative predictive value (PPV and NPV) of molecular and serological tests for the diagnosis of SARS-CoV-2 infection. […] We evaluated three Reverse Transcriptase-real time PCRs (RT-PCRs) including six different gene targets, five serologic rapid diagnostic tests (RDT) and one ELISA. | 2020-09-09 |
| 32899470 | The regression adjusted by age, gender, and diagnosis of other chronic diseases showed individuals with systemic lupus erythematosus were at a much higher risk of elevated symptoms of anxiety on the GAD-7 scale (OR = 3.683; p < 0.001), depression on the PHQ-9 scale (OR = 4.183; p < 0.001), and sleep disorders on the Insomnia Severity Index (ISI) scale (OR = 6.781; p < 0.001). | 2020-09-09 |
| 32899754 | Perspectives on how specific algae species and genetic engineering techniques can be applied for the production of anti-viral compounds antibodies and vaccines against SARS-CoV-2 are provided. | 2020-09-09 |
| 32899778 | The aim of this study was to investigate the diagnostic accuracy of symptoms and signs in healthcare workers (HCW) with Sars-CoV-2. […] Diagnostic accuracy was calculated using the sensitivity, specificity, and positive and negative predictive values. | 2020-09-09 |
| 32899935 | They have already caused millions of deaths, and the regions where malaria is endemic are at risk of further suffering from the consequences of COVID-19 due to mutual side effects, such as less access to treatment for patients with malaria due to the fear of access to healthcare centers leading to diagnostic delays and worse outcomes. […] Moreover, the similar and generic symptoms make it harder to achieve an immediate diagnosis. | 2020-09-09 |
| 32899996 | This case emphasizes the importance of early diagnosis and monitoring for antimicrobial drug-resistant coinfections to reduce their unfavorable outcomes in COVID-19 patients. | 2020-09-09 |
| 32900007 | This review summarizes the developments of commonly used testing methods and their strategic use in clinical diagnosis and epidemiologic surveillance. | 2020-09-09 |
| 32900417 | The probability of detecting positive cases of COVID-19 in Ecuador was higher than Iceland and South Korea, since the diagnostic tests were aimed at symptomatic patients, without identifying asymptomatic or mild symptomatic, who play an important role in the transmission of the disease. | 2020-09-09 |
| 32900518 | Modified NRS-2002 tool and GLIM criteria were used for nutritional risk screening and for the diagnosis of malnutrition, respectively. | 2020-09-09 |
| 32900750 | His initial treatment included steroids for concern for Pneumocystis jiroveci pneumonia, although this was later excluded as the diagnosis. | 2020-09-09 |
| 32900875 | Antiviral treatment may be considered for any previously healthy, symptomatic outpatient not at high risk for influenza complications in whom an influenza diagnosis is confirmed or suspected, if treatment can be initiated within 48 hours of illness onset, and for children whose siblings or household contacts either are younger than 6 months or have a high-risk condition that predisposes them to complications of influenza. | 2020-09-09 |
| 32900935 | The effects will continue to grow and worsen if economies begin to open without the proper precautions, including expanded diagnostic capabilities. | 2020-09-09 |
| 32900994 | With most diagnostic infrastructure dependent on specialized instruments, their exclusive reagent supplies quickly become bottlenecks, creating an urgent need for approaches to boost testing capacity. […] In collaboration with an NHS diagnostic testing lab, we report the performance of the overall workflow and detection of SARS-CoV-2 in patient samples using RT-qPCR, CRISPR-Cas13a, and RT-LAMP. […] The validated RNA extraction and RT-qPCR platform has been installed in NHS diagnostic labs, increasing testing capacity by 1000 samples per day. | 2020-09-09 |
| 32901164 | In addition, limitations of this study, including possible ways to avoid the bias in scaling exponents due to the use of different techniques are discussed. | 2020-09-09 |
| 32901353 | Confirmed COVID-19 pneumonia was defined as characteristic ground-glass bilateral CT infiltrates and positive genetic/serologic tests. | 2020-09-09 |
| 32901413 | Understanding the aspects of biological features of the virus will help the development of diagnostic tests, pharmacological therapies, and vaccines. | 2020-09-09 |
| 32901762 | This review has also covered the laboratory diagnosis of COVID-19, passing through the imaging diagnosis made by the chest tomography revealing ground glass patching opacities, and results of non-specific exams such as the total blood with lymphopenia, the coagulation tests with increased prothrombin times, as well as marked increments of the D-dimer, troponin and proinflammatory cytokines. […] In the section devoted to the specific laboratory diagnosis of COVID-19, the most used RT-PCR protocols were described and some studies on the serological diagnosis with IgA, IgM and IgG detection were detailed, including the use of rapid immunochromatographic assays and discussing the ideal period after the onset of symptoms to perform each type of test. | 2020-09-09 |
| 32901774 | A lack of protective equipment, training, diagnostic tests, and knowledge/information concerning the disease was also reported, in addition to a reduced number of nursing workers and a lack of appreciation for the profession. managerial guidelines need to be adopted for properly allocating human and material resources in the health field, including the pediatric services, in addition to providing training on standard precautions. | 2020-09-09 |
| 32902193 | In the absence of suitable antiviral drugs and vaccines, the current pandemic has created an urgent need for accurate diagnostic tools that would be helpful for early detection of the patients. […] Many tests including classical and high-throughput techniques have developed and obtained U.S. […] However, efforts are being made to develop new diagnostic tools for detection of the disease. […] Several molecular diagnostic tests such as real-time-polymerase chain reaction, real-time isothermal loop-mediated amplification (RT-LAMP), full genome analysis by next-generation sequencing, clustered regularly interspaced short palindromic repeats technique and microarray-based assays along with other techniques such as computed tomography scan, biomarkers, biosensor, nanotechnology, serological test, enzyme-linked immunosorbent assay (ELISA), isolation of viral strain in cell culture are currently available for diagnosis of COVID-19 infection. […] This review provides a brief overview of promising high-throughput techniques currently used for detection of SARS-CoV-2, along with their scope and limitations that may be used for effective control of the disease. | 2020-09-09 |
| 32902237 | Real-time reverse transcription polymerase chain reaction assay (RT-PCR) is the gold standard for diagnosis of coronavirus disease 2019 (COVID-19); however, it is not universally available and may have limitations in response times. […] The aim was to evaluate the routine blood tests for diagnosis of COVID-19, determining the diagnostic accuracy of blood biomarkers to differentiate between patients with and without COVID-19. […] Diagnostic accuracy was determined by analyzing receiver operating characteristic (ROC) curve, calculating the area under the ROC curve (AUC) and the cutoff value. […] The following diagnostic criteria for suspected COVID-19 were established with biomarker cutoff values to differentiate between COVID-19 and NON-COVID-19 patients: lymphocytes ≤ 1.0 x 109/L; eosinophils ≤ 0.02 x 109/L; ferritin > 125% of upper reference limit (URL); LDH > 125% of URL; hsCRP > 80 mg/L; and D-dimer > 1.2 mg/L. […] Of those determined to be COVID-19 patients, 91% met one or more of the diagnostic criteria with these blood biomarkers, and of the NON-COVID-19 patients, 47% did not met any diagnostic criteria. […] Blood counts of lymphocytes and eosinophils, and plasma levels of D-dimer, LDH, hsCRP, and ferritin can be used to differentiate patients with and without COVID-19 and as a tool for diagnosis of suspected COVID-19 in adult patients at hospital admission. | 2020-09-09 |
| 32902372 | In conclusion, we suggest that a recombination between SARS-CoV-2 and MERS-CoV RNA is possible and urge public health laboratories in high-risk areas to develop diagnostic capability for the detection of recombined coronaviruses in patient samples. | 2020-09-09 |
| 32902653 | Among 8370 patients with non-COVID-19-related hospitalizations discharged through June 17, 11 (0.1%) tested positive within 14 days (median time to diagnosis, 6 days; range, 1-14 days). | 2020-09-09 |
| 32902736 | However, radiographic evaluations suggest the diagnosis of COVID-19 infection. | 2020-09-09 |
| 32903195 | Providers rated their satisfaction and responded to open-ended questions assessing challenges, strategies used to address challenges, the diagnostic process, treatment, and the patient-provider relationship. […] Challenges related to the delivery modality, diagnostic process, and patient-provider relationship differed by provider specialty (P=.046, P<.001 and p=“.02,” respectively> | 2020-09-09 | </.001>
| 32903199 | As COVID-19 has proven to be a moving target as far as its management is concerned, we will use current definitions according to the Ministry of Health (MOH) guidelines for diagnosis, treatment, and recovery. | 2020-09-09 |
| 32903229 | Imported patients had earlier onset (p < 0.001) and diagnosis (p < 0.001), but longer interval from onset to admission (p = 0.030), diagnosis (p = 0.003) and discharge (p = 0.016). […] Imported and local cases differed in the intervals from onset to admission, diagnosis and discharge. | 2020-09-09 |
| 32903303 | Through the lessons of this experience on the aggressive diagnosis and quarantine measures of COVID-19 patients, we hope medical staff avoid more infections in serious epidemic areas. | 2020-09-09 |
| 32903324 | Methods: We used data from a single large UK Cancer Center to assess the demographic/clinical characteristics of 156 cancer patients with a confirmed COVID-19 diagnosis between 29 February and 12 May 2020. […] An initial cancer diagnosis >24 months before COVID-19 [OR: 1.74 (95% CI: 0.71-4.26)], presenting with fever [6.21 (1.76-21.99)], dyspnea [2.60 (1.00-6.76)], gastro-intestinal symptoms [7.38 (2.71-20.16)], or higher levels of C-reactive protein [9.43 (0.73-121.12)] were linked with greater COVID-19 severity. […] Being of Asian ethnicity [3.73 (1.28-10.91)], receiving palliative treatment [5.74 (1.15-28.79)], having an initial cancer diagnosis >24 months before [2.14 (1.04-4.44)], dyspnea [4.94 (1.99-12.25)], and increased CRP levels [10.35 (1.05-52.21)] were positively associated with COVID-19 death. […] Conclusions: A longer-established diagnosis of cancer was associated with increased severity of infection as well as COVID-19 death, possibly reflecting the effects a more advanced malignant disease has on this infection. | 2020-09-09 |
| 32903503 | Performance of the 4 kits indicated the suitability of these for diagnosis and follow-up testing of COVID-19. | 2020-09-09 |
| 32903780 | Adherent safety behavior could be significantly explained by cancer diagnosis, increased COVID-19-related fear and subjective level of information about COVID-19, R2 = 0.215, F(3) = 27.026, p < 0.001. | 2020-09-09 |
| 32903802 | Coronavirus testing kits have been in short supply, and early diagnostic reagents did not have high sensitivity. | 2020-09-09 |
| 32903849 | Early diagnosis of infected individuals will play an important role in stopping its further escalation. […] However, several recent papers suggested that saliva-based testing is a promising alternative that could simplify and accelerate COVID-19 diagnosis. […] Conclusion: Saliva tests offer a promising alternative to NPS for COVID-19 diagnosis. […] However, further diagnostic accuracy studies are needed to improve their specificity and sensitivity. | 2020-09-09 |
| 32904395 | X-ray and computed tomography (CT) images scanning is one of the most encouraging exploration zones; it can help in finding and providing early diagnosis to diseases and gives both quick and precise outcomes. | 2020-09-09 |
| 32904454 | These findings highlight that personal experiences related to the diagnosis of COVID-19, mortality in acquaintances, and COVID-19 associated stress is associated with a greatly elevated risk of emotional disorder symptomatology and that the COVID-19 pandemic may result in increased demand for mental health services. | 2020-09-09 |
| 32904468 | M-protein induces the highest frequencies of CD4+ T cells, suggesting its relevance for diagnosis and vaccination. | 2020-09-09 |
| 32904474 | A Likert score based on chest radiography of symptomatic patients of #COVID19 can be used as a diagnostic and triaging tool in the emergency room to help physicians identify patients with likelihood of COVID-19 and triage them appropriately https://bit.ly/3gDxzDK. | 2020-09-09 |
| 32904594 | The diagnosis of coronavirus disease 2019 (COVID-19) is based on positivity of nucleic acid amplification tests (NAAT) of respiratory samples. […] Diagnosis was made by serology (positive IgM + IgA and IgG) from patient’s serum sample of day 10 after symptoms’ initiation. | 2020-09-09 |
| 32904625 | Four novel ionic liquid tagged azo-azomethine derivatives (L1-L4) have been prepared by the condensation reaction of azo-coupled ortho-vaniline precursor with amino functionalised imidazole derivative and the synthesized derivatives (L1-L4) have been characterized by different analytical and spectroscopic techniques. | 2020-09-09 |
| 32904638 | Among the aerosol generating procedures, bronchoscopy in particular is an indispensable diagnostic and therapeutic tool that comes with a high risk of infection. | 2020-09-09 |
| 32904703 | Diagnostic accuracy, sensitivity and specificity were calculated for two different scenarios: in the first, only typical findings on CT were considered positive; in the second, both typical and indeterminate findings were considered positive. […] Mean patients’ age was 58.2 years, most were male (60.4%) and had prior diagnosis of cancer (85.7%). […] CT has a high accuracy for the diagnosis of SARS-CoV-2 infection. | 2020-09-09 |
| 32904752 | Lung ultrasound is a well-defined diagnostic modality in the point of care emergency medicine concept. […] Recognize how the diagnostic possibilities of ultrasound in the approach of COVID-19 and its differential diagnoses are fundamental. | 2020-09-09 |
| 32904780 | Diagnosis primarily depends on viral detection in respiratory samples; however, available kits are limited, lack high sensitivity, and have a long turnaround time for providing results. | 2020-09-09 |
| 32904861 | While current diagnostic methods are mainly based on PCR, they suffer from insensitivity. […] In this paper, we review some of the aspects associated with the development of antibodies against SARS-CoV-2 and their potential use for improved diagnosis and therapy. | 2020-09-09 |
| 32904889 | The change in acoustic score following decongestant is key in this diagnostic process. […] Diagnostic accuracy study-Level III. | 2020-09-09 |
| 32904904 | The advantages of Computerized algorithms to facilitate better screening, diagnosis or follow-up and use of Artificial Intelligence (AI) to aid in medical diagnosis are discussed. | 2020-09-09 |
| 32904925 | Diagnostic and support services (physiotherapy, nursing care, psychological support) were suspended in 57% of centers (66/43/44% in Northern, Central and Southern centers respectively) Overall, the most affected services were rehabilitative services and on-site outpatient visits, which were suspended in 93% of centers. | 2020-09-09 |
| 32904937 | The present study relies on recent annual time-series data to conceptualize the hypothesized claim via Pesaran’s Autoregressive distributed lag techniques. | 2020-09-09 |
| 32904960 | Necessary screenings must be performed to control the spread of the COVID-19 in daily life and to make a preliminary diagnosis of suspicious cases. […] According to the obtained results, it is seen that the proposed method has leveraging performance, especially to make the diagnosis of COVID-19 in a short time and effectively. | 2020-09-09 |
| 32905025 | We captured data on work patterns, aerosolizing procedures, testing and diagnosis of COVID-19. | 2020-09-09 |
| 32905026 | Graft copolymerization and other techniques assist PVP to conjugate with poorly soluble drugs that can inflate bioavailability and even introduces the desired swelling tract for their control or sustained release. | 2020-09-09 |
| 32905045 | Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%-50% of nose/throat swabs being negative by SARS-CoV-2 nucleic acid amplification testing (NAAT). […] We assess the diagnostic accuracy of combined rapid antibody point of care (POC) and nucleic acid assays for suspected COVID-19 disease due to either wild-type or the D614G spike mutant SARS-CoV-2. […] The combined point of care antibody test and rapid NAAT is not affected by D614G and results in very high sensitivity for COVID-19 diagnosis with very high specificity. | 2020-09-09 |
| 32905265 | This diagnostic validation study included patients attending the outpatient department of the institute. | 2020-09-09 |
| 32905464 | COVID-19 can have a multifaceted presentation, which can be a diagnostic challenge. | 2020-09-09 |
| 32905485 | We describe a case of Epstein-Barr virus (EBV) associated HLH with its typical diagnostic challenges and associated high mortality rate. […] Certain diagnostic criteria and online tools may help to arrive at an earlier presumptive diagnosis which, in turn, may expedite treatment and lead to better clinical outcomes. | 2020-09-09 |
| 32905504 | The crisis has also brought great challenges to the routine diagnosis and treatment of cancer patients, especially given the urgency and continuity of cancer care. | 2020-09-09 |
| 32905568 | The pandemic of COVID-19 requires rapid and easy access to reliable imaging modalities for diagnosis and follow up. […] Considering the cost-effectiveness of the imaging used, ultrasound is a non-ionizing, portable and bedside imaging modality with a high diagnostic impact in emergencies and intensive care units in pandemics, but it is operator dependent. […] In our article, we provide a comprehensive review of the role of point-of-care ultrasound in the diagnosis of COVID-19 infection and its impact on the lungs, cardiovascular system, eyes and abdominal organs. […] Moreover, ultrasound can provide real-time diagnostic and therapeutic interventions, such as the placement of a central catheter and aspiration of pericardial effusion. | 2020-09-09 |
| 32906596 | The results confirm that rapid serological assays alone are not sufficient for diagnosis of SARS-CoV-2 infection but can be incorporated into large-scale screening programs during periods in which the virus circulation is low. | 2020-09-10 |
| 32907358 | Currently, the Chinese National Health Commission recommended a TCM prescription of Qing-Fei-Pai-Du-Tang (QFPDT) in the latest version of the “Diagnosis and Treatment guidelines of COVID-19” which has been reported to provide reliable effects for COVID-19. | 2020-09-10 |
| 32907362 | Critical care medicine is a medical specialty engaging the diagnosis and treatment of critically ill patients who have or are likely to have life-threatening organ failure. | 2020-09-10 |
| 32907581 | The database contains the number of COVID-19 diagnostic tests performed, the number of confirmed cases and deaths in Israel. | 2020-09-10 |
| 32907595 | Serial serologic tests for SARS-CoV-2 IgG and IgA showed seroconversion, consistent with an acute infection. […] Decompressive suboccipital craniectomy for brain herniation with cerebellar biopsy on day 30 of illness, shortly before death, revealed SARS-CoV-2 RNA in cerebellar tissue using the Centers for Disease Control and Prevention 2019-nCoV Real-Time Reverse Transcriptase-PCR Diagnostic Panel. | 2020-09-10 |
| 32907635 | Primary outcome: a composite of any hospitalization or all-cause death occurring within 30 days of randomization. (i) a composite of cardiovascular events, including deep vein thrombosis (including catheter-associated), pulmonary embolism, myocardial infarction/myocarditis, arterial ischemia including mesenteric and extremities, acute splanchnic vein thrombosis, or ischemic stroke within 14 days, 30 days, and 90 days of randomization; (ii) each component of the primary efficacy outcome, within 14 days, 30 days, and 90 days of randomization; (iii) net clinical benefit (accounting for the primary efficacy outcome, composite cardiovascular events, and major bleeding), within 14 days, 30 days, and 90 days of enrolment; (iv) primary efficacy outcome, within 14 days, and 90 days of enrolment; (v) disseminated intravascular coagulation (ISTH criteria, in-hospital diagnosis) within 14 days, 30 days, and 90 days of enrolment. | 2020-09-10 |
| 32907637 | The purpose of this review is primarily reviewing the COVID-19 disease, including pathogen, clinical features, diagnosis, and treatment with particular attention to cardiovascular involvement based on the current evidence. | 2020-09-10 |
| 32907676 | To correlate the clinical, laboratory, and radiographic characteristics of patients with a confirmed diagnosis of COVID-19 disease, with fatal outcome. […] We reviewed Chest X-Ray (CXR) features, clinical, and laboratory data of patients with RT-PCR confirmed diagnosis of COVID-19 infection. | 2020-09-10 |
| 32907844 | The current COVID-19 pandemic is causing diagnostic and risk stratification difficulties in Emergency Departments (ED) worldwide. […] Chest x-ray (CXR) is a poor diagnostic test for COVID-19, and computed tomography (CT), while sensitive, is impractical as a diagnostic test for all patients. […] LUS shows characteristic changes in viral pneumonitis, and while these changes are not specific for COVID-19, it may be a useful adjunct during the diagnostic process. | 2020-09-10 |
| 32907891 | Cases were collected retrospectively from UK hospitals with inclusion criteria limited to a diagnosis of COVID-19 and the presence of either pneumothorax or pneumomediastinum. | 2020-09-10 |
| 32908070 | This situation prompted us to look into the challenges African laboratories are facing in the diagnosis of novel COVID-19 infection. […] The choice of diagnostic method in Africa is limited as there are only two available diagnostic methods being used out of the six methods used globally, thereby reducing the opportunity of supplementary diagnosis, which will further lead to inappropriate diagnosis and affect the accuracy of diagnostic reports. […] From the observations, there is an urgent need for more investment into the laboratories for proper, timely, and accurate diagnosis of COVID-19. | 2020-09-10 |
| 32908126 | Here, we use a semi-Bayesian probabilistic bias analysis to account for incomplete testing and imperfect diagnostic accuracy. […] The approach can readily be applied in future studies in other locations or at finer spatial scale to correct for biased testing and imperfect diagnostic accuracy to provide a more realistic assessment of COVID-19 burden. | 2020-09-10 |
| 32908530 | Therefore, the first step in combating viral pathogens is to get a timely and accurate diagnosis. […] Here, we summarize some of the molecular and immunological diagnostic approaches available for the detection of viral infections of humans. […] Molecular diagnostic techniques provide rapid viral detection in patient sample. […] They are also relatively inexpensive and highly sensitive and specific diagnostic methods. […] Immunological-based techniques have been extensively utilized for the detection and epidemiological studies of human viral infections. […] There are several commercially available molecular and immunological diagnostic kits that facilitate the use of these methods in the majority of clinical laboratories worldwide. | 2020-09-10 |
| 32908705 | The main aim of this study is to review and summarize the evidence regarding the supportive role of physical rehabilitation techniques in managing COVID-19-associated pneumonia. […] In this review, we also emphasize the use of rehabilitation techniques in the management of pneumonia in COVID-19-infected patients. […] Based on the evidence presented, we conclude that certain physical rehabilitation techniques and modalities could be of great support in the management of COVID-19-associated pneumonia. […] Many rehabilitation techniques are safe and feasible and can be easily incorporated into the management protocol of COVID-19 victims. | 2020-09-10 |
| 32909049 | Lung ultrasound is able to depict typical pulmonary findings of COVID-19 and is therefore suitable for diagnosis and follow-up of these patients. | 2020-09-10 |
| 32909090 | The curve of interstitial pneumonia diagnosis overlapped with the COVID-19 incidence in the area of Lombardy (Spearman correlation index was equal to 1). | 2020-09-10 |
| 32909234 | EPN requires early diagnosis and treatment due to the possible life-threatening septic complications. […] A 62-year-old male with diabetes mellitus (DM) presented with abdominal pain, shortness of breath, and nausea in which a diagnosis of septic shock was made due to EPN. | 2020-09-10 |
| 32909852 | A total of 46 (telehealth, n=19 and standard care, n= 27) patients (40 female) with a median age of 32 (range 17-74) years at diagnosis were included in the study. | 2020-09-10 |
| 32909925 | Here we used MD simulations and docking techniques to investigate these structural differences in DPP4 receptors. | 2020-09-10 |
| 32910251 | It is difficult to diagnose, especially in compromised COVID-19 patients but should be kept in mind as early diagnosis and treatment are crucial. | 2020-09-10 |
| 32910323 | Diagnostic value of point-of-care lung ultrasound (POCUS) in detection of coronavirus disease (COVID-19) in an emergency setting is currently unclear. […] In this study, we aimed to compare diagnostic performance, in terms of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy, of POCUS lung, chest CT, and RT-PCR for clinically suspected COVID-19 infections in patients submitting to the emergency room (ER). | 2020-09-10 |
| 32910408 | In this audit we sought to distinguish COVID-19 hospitalised patients with a diagnosis of venous thromboembolism (VTE) and record their outcomes over a period of 3 months (01/02/2020-30/04/2020). | 2020-09-10 |
| 32910433 | A 0.125% pilocarpine test confirmed Adie’s pupil diagnosis. | 2020-09-10 |
| 32910456 | Neither diagnosis nor disease status affected the prognosis. […] Neither diagnosis nor disease status influence the prognosis. | 2020-09-10 |
| 32910817 | Accessibility of diagnostic testing for COVID-19 has been limited by intermittent shortages of supplies required for testing, including flocked nasopharyngeal (FLNP) swabs. […] The performance of 3DP and FLNP swabs were compared in a clinical trial of symptomatic patients at three clinical sites (n=291) using three SARS-CoV-2 EUA tests: a modified version of the CDC Real-time Reverse Transcriptase (RT)-PCR Diagnostic Panel and two commercial automated formats, Roche Cobas and NeuMoDx. […] The overall clinical correlation of COVID-19 diagnosis between all methods was 95.88% (Kappa 0.901). | 2020-09-10 |
| 32910943 | We excluded studies reporting neonates with perinatal COVID exposure and diagnosis prior to hospital discharge and hospital-onset disease, as well as clinically diagnosed cases without confirmation. | 2020-09-10 |
| 32910979 | A lower COI limit for reactivity (≥0.55, using the 99th percentile COI of our controls and ROC analysis) improved diagnostic sensitivity, especially at 0-6 days POS (45.9-55.8%), with a small decrease in specificity (98.9%). | 2020-09-10 |
| 32911064 | The ongoing crisis due to the global pandemic caused by a highly contagious coronavirus (Coronavirus disease - 2019; COVID-19) and the lack of either proven effective therapy or a vaccine has made diagnostic a valuable tool in disease tracking and prevention. […] The complex nature of this newly emerging virus calls for scientists’ attention to find the most reliable, highly sensitive, and selective detection techniques for better control or spread of the disease. […] Nano biosensor technology platforms have been established as a promising diagnostic tool for rapid and accurate detection of viruses as well as other life-threatening diseases even in resource-limited settings. […] This review aims to provide a short overview of recent advancements in molecular and biosensor-based diagnosis of viruses, including the human coronaviruses, and highlight the challenges and future perspectives of these detection technologies. | 2020-09-10 |
| 32911110 | The diagnosis was confirmed using polymerase chain reaction testing of nasopharyngeal specimens. | 2020-09-10 |
| 32911861 | This user-dependency manifests itself as a factor impeding the digital transformation of this valuable diagnostic tool, which can improve patient outcomes by continuous long-term respiratory monitoring under real-life conditions. | 2020-09-11 |
| 32912226 | Future studies are needed to better understand the involvement of the microvasculature in coronavirus neuropathology, and to test the diagnostic potential of minimally-invasive screening tools (e.g. serum biomarkers, fluorescein retinal angiography and dynamic-contrast MRI). | 2020-09-11 |
| 32912236 | Fast point-of-care (POC) diagnostics represent an unmet medical need and include applications such as lateral flow assays (LFAs) for the diagnosis of sepsis and consequences of cytokine storms and for the treatment of COVID-19 and other systemic, inflammatory events not caused by infection. […] Our assay is applicable for detecting clinically relevant ranges of both target proteins and therefore may serve as a powerful tool for POC diagnosis of inflammation and infectious events. | 2020-09-11 |
| 32912370 | Sixty-six per cent of confirmed COVID-19 cases were asymptomatic at diagnosis. | 2020-09-11 |
| 32912527 | The consequences of lack of diagnosis and treatment of a large proportion of acute stroke patients are likely severe and lasting. | 2020-09-11 |
| 32912559 | Diagnostic workup excluded cardiac embolic sources, acquired and inherited thrombophilia or autoimmune diseases. […] Two positive nasopharyngeal swab tests and high titers of serum specific IgA/IgM confirmed COVID-19 diagnosis. | 2020-09-11 |
| 32912655 | This study reviewed the tracheostomy provision, techniques, and outcomes for a single-centre prospective cohort during the resource-pressured COVID-19 period. | 2020-09-11 |
| 32912745 | In 5 of the 15 patients with clinical myopathy, diagnosis was confirmed with electroneuromyography. | 2020-09-11 |
| 32912964 | More than 2 in 3 of the overall cohort had had contacts with the health and social care system prior to diagnosis. | 2020-09-11 |
| 32913038 | HbA1c is a biomarker with a central role in the diagnosis and follow-up of patients with diabetes, although not a perfect one. | 2020-09-11 |
| 32913297 | We also highlight vaccine and diagnostic production platforms that are being developed in Africa and that could be translated into clinical development through appropriate partnerships for manufacture. | 2020-09-11 |
| 32913621 | In addition to symptoms, laboratory tests (BNP and troponin), echocardiogram and cardiac MRI contributed to diagnosis. | 2020-09-11 |
| 32913866 | Real-time fluorescence polymerase chain reaction confirmed the diagnosis of COVID-19. | 2020-09-11 |
| 32914188 | Physical therapists have a unique role in both prevention of VTE through the promotion of early mobility and physical activity and diagnosis through discovery of signs and symptoms of VTE. | 2020-09-11 |
| 32914189 | Occurrence of putative invasive pulmonary aspergillosis was screened in 153 consecutive adult intensive care unit (ICU) patients with respiratory samples addressed for mycological diagnosis during a 6-week period at the emergence of coronavirus disease 2019 (COVID-19) pandemic. […] Adult ICU patients with respiratory samples addressed for mycological diagnosis were screened during the emergence of COVID-19 pandemic. | 2020-09-11 |
| 32914217 | The median time from admission to diagnosis of SARS-CoV-2 infection in our cohort was 16 days (6-86 days). | 2020-09-11 |
| 32914439 | The specific antigenic characteristics are critical for developing specific immune-based rapid diagnostic tests. | 2020-09-11 |
| 32914632 | Such computational immunoproteomics studies may as well prepare and guide lab-based investigations, representing valuable technology for the investigation of novel pathogens, to tentatively evaluate specificity of diagnostic products, to forecast on potential adverse effects of vaccines and to reduce the use of animal models. | 2020-09-11 |
| 32914690 | The graphene system could find potential applications in personal protective equipment and diagnostic kits. | 2020-09-11 |
| 32914699 | We critically examine the current evidence whether and how the SARS-CoV-2 virus can follow a route from the olfactory epithelium in the nose to the brain to achieve brain infection, and we discuss the prospects for using the smell and taste dysfunctions seen in COVID-19 as an early and rapid diagnostic screening tool. | 2020-09-11 |
| 32914767 | The patients were divided into a severe group and a non-severe group according to diagnosis and classification, which followed the guidelines and management of the Chinese National Health Council COVID-19. | 2020-09-11 |
| 32915072 | Adults admitted to ICU with a confirmed diagnosis of COVID-19 and mechanically ventilated for >24 hours were included. | 2020-09-11 |
| 32915271 | We identified sarcoidosis patients who met diagnostic criteria for sarcoidosis according to accepted guidelines. […] While the diagnosis of sarcoidosis was not independently associated with risk of an adverse event, (aOR 1.8, 95% CI 0.9-3.6), the diagnosis of sarcoidosis in patients with moderately and/or severely impaired pulmonary function was associated with an adverse outcome (aOR 7.8, 95% CI 2.4-25.8). | 2020-09-11 |
| 32915476 | However, the diagnosis and treatment of the disease need further exploration. […] Therefore, this retrospective analysis was conducted on multiple indicators of peripheral blood in patients with COVID-19 to determine the role of leukocytes, lymphocytes, and eosinophils in the diagnosis and prognostic evaluation of COVID-19. […] Thus, it could be deduced that eosinophils have better sensitivity for the diagnosis of COVID-19 and play a major role similar to lymphocytes in assessing the prognosis of patients. | 2020-09-11 |
| 32915650 | This will have important implications for future diagnostic and therapeutic developments for patients infected with COVID-19. | 2020-09-11 |
| 32915751 | With the continuous growth of new infections, developing automated tools for COVID-19 identification with CT image is highly desired to assist the clinical diagnosis and reduce the tedious workload of image interpretation. […] We develop and evaluate our method with two public large-scale COVID-19 diagnosis datasets made up of CT images. | 2020-09-11 |
| 32915818 | In the early days of pandemic emergence we developed an online survey open to all Italian clinicians involved in the diagnosis and management of COVID-19 patients. | 2020-09-11 |
| 32915899 | A similar effect was also observed around the public health (e.g., masks in public spaces; Yoga and Ayurveda for immunity), transport (e.g., old trains converted to isolation wards), micro, small and medium enterprises (e.g., rapid production of PPE and masks), science and technology sector (e.g., diagnostic kits, robots and nano-technology), home affairs (e.g., surveillance and lockdown), urban (e.g. drones, GIS-tools) and education (e.g., online learning). | 2020-09-11 |
| 32916249 | Therefore, what low cost solutions remain for the prevention, diagnosis, and treatment of SARS-CoV-2? | 2020-09-11 |
| 32916565 | This is a single center retrospective analysis of 355 adult patients with confirmed diagnosis of COVID-19 from March 1 to May 31, 2020. | 2020-09-11 |
| 32916610 | Overall, our technology can greatly facilitate rapid, sensitive, and quantitative analysis of COVID-19 related markers for therapeutic, diagnostic, epidemiologic, and prognostic purposes. | 2020-09-11 |
| 32916744 | After a third attempt for a PCR-analysis of a deep oral swab-sample was negative, analysis of a sputum was performed which finally confirmed the diagnosis of COVID-19 associated pneumonia. […] Due to clinical recovery antiviral therapy was not performed after confirming the diagnosis. […] Finally, PCR-analysis of sputum confirmed the diagnosis. | 2020-09-11 |
| 32916801 | The diagnostic sensitivity of the self-collected and HCW-collected swabs was 84.2% and 89.5%, respectively, with an acceptable agreement, Cohens kappa 0.82, p < 0.001. | 2020-09-12 |
| 32916926 | MBA is robust, simple and is suitable for clinical microbiology laboratory for the accurate determination of anti-SARS-CoV-2 antibodies for diagnosis, serosurveillance, and vaccine trials. | 2020-09-12 |
| 32917141 | The specimens in this biorepository will allow necessary comparative studies between children and adults, help determine the accuracy of current pediatric viral testing techniques, in addition to, understanding neonatal exposure to SARS-CoV-2 infection and disease abnormalities. | 2020-09-12 |
| 32917254 | Protocols that allow for easy over-diagnosis can be disadvantageous, mainly because of treatment delays, and therefore, the protocols must be developed in light of the local infection situation. | 2020-09-12 |
| 32917282 | Most studies considered the definite clinical diagnosis as the primary outcome, variably coupled with other outcomes (severity was the most frequently analysed). | 2020-09-12 |
| 32917294 | PCR of upper respiratory specimens is the diagnostic standard for severe acute respiratory syndrome coronavirus 2 infection. | 2020-09-12 |
| 32917716 | Therefore, there is an urgent need to increase diagnostic testing capabilities to prevent disease spread. […] P- BEST provides an efficient and easy-to-implement solution for increasing testing capacity that can be easily integrated into diagnostic laboratories. | 2020-09-12 |
| 32917729 | A large number of serologic tests, platforms and methodologies are being employed to determine seroprevalence in populations to select convalescent plasmas for therapeutic trials, and to guide policies about reopening. | 2020-09-12 |
| 32917746 | This report supports a strategy of combining repeat swabbing, use of acute and convalescent antibody testing and CT thorax for COVID-19 diagnosis. | 2020-09-12 |
| 32918295 | NLR is an easily measurable, available, cost-effective and reliable parameter, which continuous monitoring could be useful for the diagnosis and treatment of COVID-19. | 2020-09-12 |
| 32918466 | IDSA’s goal was to develop evidence-based recommendations that assist clinicians, clinical laboratories, patients and policymakers in decisions related to the optimal use of SARS-CoV-2 serologic tests in a variety of settings. […] We also highlight important unmet research needs pertaining to the use of anti-SARS-CoV-2 antibody tests for diagnosis, public health surveillance, vaccine development and the selection of convalescent plasma donors. […] A multidisciplinary panel of infectious diseases clinicians, clinical microbiologists and experts in systematic literature review identified and prioritized clinical questions related to the use of SARS-CoV-2 serologic tests. […] The panel agreed on eight diagnostic recommendations. […] Information on the clinical performance and utility of SARS-CoV-2 serologic tests are rapidly emerging. […] The panel identified three potential indications for serologic testing including: 1) evaluation of patients with a high clinical suspicion for COVID-19 when molecular diagnostic testing is negative and at least two weeks have passed since symptom onset; 2) assessment of multisystem inflammatory syndrome in children; and 3) for conducting serosurveillance studies. […] The certainty of available evidence supporting the use of serology for either diagnosis or epidemiology was, however, graded as very low to moderate. | 2020-09-12 |
| 32918497 | This may be highest during invasive diagnostic procedures releasing aerosols and droplets. […] Thereby, the use of diagnostic procedures for Covid-19 associated aspergillosis may be delayed or impeded, as use of bronchoscopy has been discouraged. | 2020-09-12 |
| 32918696 | Age, sex, education, clinical characteristics (including diagnosis of dementia) and flu vaccination history were obtained from previous medical records. | 2020-09-12 |
| 32918747 | Most diagnostic histopathologists have limited understanding of the ultrastructural features of normal cell trafficking pathways, which can resemble intra- and extracellular coronavirus; in addition, viral replication pathways make use of these trafficking pathways. | 2020-09-12 |
| 32918761 | Eligible patients were hospitalized and required to have positive nasopharyngeal polymerase chain reaction (PCR) diagnosis of SARS-CoV-2 infection, be at least 18 years old, and have either dyspnea, blood oxygen saturation ≤ 93% on ambient air, respiratory frequency ≥ 30 breaths/min, partial pressure of arterial oxygen to fraction of inspired oxygen ratio < 300, or lung infiltrates > 50%. | 2020-09-12 |
| 32918932 | Since SARS-CoV-2 testing in most locations occurs once COVID-19 symptoms are evident and, therefore, viral loads are expected to be high, our protocol will be useful in supporting SARS-CoV-2 diagnosis, especially in America where COVID-19 cases have exploded in the recent weeks as well as in low- and middle-income countries, which would not have massive access to kit-based diagnosis. | 2020-09-12 |
| 32919074 | To evaluate the efficacy of sample pooling compared to the individual analysis for the diagnosis of coronavirus disease 2019 (COVID-19) by using different commercial platforms for nucleic acid extraction and amplification. | 2020-09-12 |
| 32919186 | Image-based AI is more important than ever as the pandemic surges and countries worldwide grapple with limited medical resources for detection and diagnosis. | 2020-09-12 |
| 32919240 | Eligibility criteria: We evaluated studies including patients with diagnosis of COVID 19 and a past history of stroke. | 2020-09-12 |
| 32919586 | Given the predicted need for continued SARS-CoV-2 diagnostic testing, as well as the evolving availability and types of diagnostic tests, off-site COVID-19 testing centers (OSCTC) leaders need timely guidance to ensure they are meeting the needs of their unique populations. | 2020-09-13 |
| 32919683 | Further, the review highlights the method of fabrication, biohybrid nanomotors, toxicities along with their application in the field of active drug delivery, diabetes, precise surgery, ischemic stroke therapy, diagnosis and treatment of coronavirus, microwave hyperthermia, zika virus detection, anti-bacterial activity, water treatment and sensing and challenges lying at the forefront in the development of these tiny nanomachines. | 2020-09-13 |
| 32919836 | However, while STEMI on electrocardiogram (ECG) is not always associated with acute coronary occlusion, this diagnostic uncertainty should not delay cardiac catheterization. | 2020-09-13 |
| 32919879 | COVID-19 antibodies can be isolated or delivered using a number of other techniques including: plasmapheresis, plasma cryoprecipitate reduced (cryosupernatant), antibody hyperconcentrates and advanced cell-based delivery systems. | 2020-09-13 |
| 32920079 | It is followed by reviewing the advances in using magnetic particles for diagnosis and therapy of lung cancers: (i) a combination of magnetic particle targeting with MRI imaging for diagnosis and screening of lung cancers, (ii) magnetic drug targeting (MDT) through either intravenous injection and pulmonary delivery for lung cancer therapy, and (iii) computational simulations that models new and effective approaches for magnetic particle drug delivery to the lung, all supporting improved lung cancer treatment. […] The review further discusses future opportunities to improve the clinical performance of MDT for diagnosis and treatment of lung cancer and highlights clinical therapy application of the MDT as a new horizon to cure with minimal side effects a wide variety of lung diseases and possibly other acute respiratory syndromes (COVID-19, MERS, and SARS). | 2020-09-13 |
| 32920162 | Our study included 614 patients who were hospitalized with the diagnosis of COVID-19 between 03.16.20 and 05.12.20. | 2020-09-13 |
| 32920232 | All consecutive patients admitted to the Infectious Diseases Unit and Intensive Care Unit (ICU) of Santa Maria Annunziata Hospital (Florence, Italy), from February 25 to April 25, 2020, with a confirmed COVID-19 diagnosis were enrolled in this retrospective cohort study. | 2020-09-13 |
| 32920452 | This response to COVID-19 can be monitored based on the production of antibodies, and thus, serologic tests have become available for diagnostic purposes. | 2020-09-13 |
| 32920569 | Pulmonary Ultrasound (LUS) could be a valid diagnostic alternative for the imaging of COVID-19. | 2020-09-13 |
| 32920634 | The evolving, highly contagious global viral spread has created a pressure test of unprecedented proportions for the existing brain health care infrastructure and related services for management, diagnosis, treatment, and prevention. | 2020-09-13 |
| 32921005 | Although IRTs have significant potential for human body temperature measurement, the literature indicates inconsistent diagnostic performance, possibly due to wide variations in implemented methodology. […] Perform a clinical study to assess the diagnostic effectiveness of standardized IRT-based fever screening and evaluate the effect of facial measurement location. | 2020-09-13 |
| 32921197 | We describe pragmatic strategies we have implemented to overcome diagnostic obstacles caused by the local tuberculosis (TB) and HIV epidemics in South Africa, which may serve as a guide to minimize diagnostic delay during the COVID-19 pandemic. […] We report on the diagnostic utility of a rapid-access lymph node core-biopsy clinic, where lymph node biopsies are taken from outpatients at their first visit. […] Compared with a historical cohort, the diagnostic interval (time from first health visit to diagnostic biopsy) for patients with lymphoma was significantly shorter, 13.5 vs 48 days (p = 0.002). | 2020-09-14 |
| 32921214 | The implications of the closure of many healthcare services over the initial lockdown will also have both a shorter- and longer-term impact on other diseases due to missed early diagnosis and disrupted treatment regimes. | 2020-09-14 |
| 32921332 | Difficulties in access to diagnostic tests, lack of hospital equipment, but also the large number of people working in the informal sector (such as trading, businesses, transport and restoration) makes it difficult to apply preventive measures, namely physical distancing and containment. | 2020-09-14 |
| 32921515 | Predictors of requiring consultation were Clinical Dementia Rating scores ≥1 (P<.001 and diagnosis of alzheimer disease> | 2020-09-14 | </.001>
| 32921704 | The peaks of weekly Google searches for “febbre” (fever), “tosse”(cough) and “dispnea” (dyspnea) were 1.7-, 2.2- and 7.7-fold higher compared to the week before the diagnosis of the first national case. | 2020-09-14 |
| 32921716 | Therefore, it is important to analyse their diagnostic ability and limitations and to consider other methods of diagnosing COVID 19. […] Additionally, RT-PCR testing can have significant rates of false negatives, indicating the importance of taking a more comprehensive diagnostic approach. | 2020-09-14 |
| 32921720 | Early diagnosis of COVID-19 is paramount for disease treatment and infection control. […] Naso-pharyngeal (NP) swab is commonly used as screening and diagnostic tool for COVID-19, but in some cases it can be resulted negative even in presence of clinical and epidemiological criteria, and typical radiological and laboratory findings of COVID-19, as we have observed. | 2020-09-14 |
| 32921721 | In conclusion, diagnostic tests based on salivary specimens are somewhat reliable, but relatively few studies have been carried out. | 2020-09-14 |
| 32921726 | This narrative review aims to provide a comprehensive overview of epidemiological, pathogenic and clinical features, along with diagnosis and treatment, of the ongoing epidemic of new coronavirus disease 2019 (COVID-19) in the pediatric population in comparison to the first two previous deadly coronavirus outbreaks, SARS and MERS. | 2020-09-14 |
| 32921736 | For how long can selected surgery be deferred without compromising outcomes and mid to long term mortality in oncological patients in our province, considering also the diagnostic-therapeutic delays in these exceptional months of the Covid era? | 2020-09-14 |
| 32921862 | Among already existing, widely available and low-cost resources, X-ray is frequently used imaging modality and on the other hand, deep learning techniques have achieved state-of-the-art performances in computer-aided medical diagnosis. […] Therefore, an alternative diagnostic tool to detect COVID-19 cases utilizing available resources and advanced deep learning techniques is proposed in this work. […] This study is performed with online available resources of 1215 images and further strengthen by utilizing data augmentation techniques to provide better generalization of the model and to prevent the model overfitting by increasing the overall length of dataset to 1832 images. | 2020-09-14 |
| 32921925 | Consequently, it is crucial to maintain sufficient sample capacities in diagnostic laboratories. | 2020-09-14 |
| 32921934 | Overall, our CVDNet model can be an interesting tool to help radiologists in the diagnosis and early detection of COVID-19 cases. | 2020-09-14 |
| 32921952 | Collected data included age distribution, traumatic etiology, diagnosis and type of surgical procedures. […] Analyzing the Hospital Discharge Records (HDR), we found a significant increase in the number of proximal and middle phalanx fractures; no significant differences were found for other kinds of discharge diagnosis. | 2020-09-14 |
| 32922115 | Several options exist for asynchronous and synchronous teaching of anesthesia skills at a distance with SBS, and there are useful techniques that can assist in achieving these educational goals with this process. | 2020-09-14 |
| 32922162 | With this, the world population is going through a process of changing habits, with social distance, improvement of hygiene techniques, to reduce the spread of the SARS-CoV-2 virus and, consequently, reduce the number of hospitalized people in serious condition, as well as the mortality rate. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922166 | It can thus facilitate decisions on further diagnostic and first therapeutic procedures, even in patients with a SARS-CoV‑2 infection who present to the emergency room. | 2020-09-14 |
| 32922212 | The effect of the current treatment protocols on patients’ diagnostic and prognostic biomarkers may thus impact the validity of the algorithms adopted. | 2020-09-14 |
| 32922217 | A multi-specialty nursing team plays a crucial role in key decision making, education, prevention, screening, assessment, diagnosis, management, data collection and dissemination of best practices during the novel coronavirus disease (COVID-19) pandemic. | 2020-09-14 |
| 32922466 | Of the 231 suspected cases of COVID-19 admitted to the hospital during two weeks, 72 patients were admitted to ICU with diagnosis confirmed by RT-PCR. | 2020-09-14 |
| 32922852 | During the COVID-19 pandemic, chest CT is frequently used to help with the diagnosis. […] However, when there are pre-existing conditions particularly in the elderly population that could mask or result in similar patterns of disease, then the diagnosis is more difficult. […] We illustrate imaging clues available to the radiologist to either make the diagnosis or at least reduce the differential diagnosis. | 2020-09-14 |
| 32922853 | The diagnosis per se is straightforward; however, the disease seems to affect multiple organs. […] We present differential diagnosis of a MRI identified solitary lesion in the splenium of the corpus callosum, in a COVID-19 positive patient with altered mental status. | 2020-09-14 |
| 32923003 | However, radiographic evaluations suggest the diagnosis of COVID-19 infection. | 2020-09-14 |
| 32923301 | Conclusion CT can facilitate the diagnosis of COVID-19 pneumonia. | 2020-09-14 |
| 32923356 | This study aims to present the reactions of travelers during the pandemic trends outlined by adopting text mining techniques. | 2020-09-14 |
| 32923397 | An additional challenge is the timely completion of the diagnostic and staging studies required to formulate appropriate treatment plans. […] Deferred procedures and avoidance of multiple trips to the surgical, diagnostic, and laboratory suites require same day consolidation of all procedures. | 2020-09-14 |
| 32923449 | For the MuLBSTA score, the ROC curve showed good efficiency of diagnosis death (area under the curve [AUC], 0.956; cutoff value, 12; specificity, 89.5%; sensitivity, 100%) and ICU care (AUC, 0.875; cutoff value, 11; specificity, 91.7%; sensitivity, 71.4%). | 2020-09-14 |
| 32923742 | A diagnosis of episcleritis was made based on clinical grounds and topical fluorometholone 0.1%. was started. […] Understanding the association between ocular signs/symptoms and COVID-19 can aid in the diagnosis of the viral infection and can help in limiting its transmission. | 2020-09-14 |
| 32924000 | Using systemized nomenclature of clinical medical terms (SNOMED-CT), we identified adults with the diagnosis of metabolic syndrome and its individual components from 1999 to 2019. […] We included patients with the diagnosis of COVID-19 from December 2019 to May 2020. […] The cumulative incidence of COVID-19 was higher if metabolic syndrome was the primary diagnosis (0.10% vs 0.01%, OR 7.00 [6.11-8.01]). | 2020-09-14 |
| 32924089 | Classic KD is a clinical diagnosis based on set criteria and excluding other similar clinical entities. […] Patients who do not fulfill complete diagnostic criteria for KD are often referred to as atypical (or incomplete) KD. | 2020-09-14 |
| 32924178 | These have been driven by rapid advances in laboratory techniques and equipment. […] There are practical and ethical reasons for this lack of translation of increasingly affordable techniques into the clinic. | 2020-09-14 |
| 32924229 | In older patients, typical clinical symptoms and blood test changes were often absent; however, CT always contained typical findings of COVID-19, suggesting that CT may be a useful diagnostic tool. | 2020-09-14 |
| 32924567 | Biomarkers related to coagulation, platelet activation and inflammation have been suggested as useful diagnostic and prognostic tools for COVID-19-associated coagulopathy; among them, D-dimer remains a key biomarker employed in clinical practice. | 2020-09-14 |
| 32924671 | Diagnostic tools are the main players that not only indicate a possible infection but can further restrict the transmission and can determine the extent to which disease progression would occur. […] In this paper, we have performed a narrative and critical review on different technology-based diagnostic strategies such as molecular approaches including real-time reverse transcriptase PCR, serological testing through enzyme-linked immunosorbent assay, laboratory and point of care devices, radiology-based detection through computed tomography and chest X-ray, and viral cell cultures on Vero E6 cell lines are discussed in detail to address COVID-19. […] This review further provides an overview of emergency use authorized immunodiagnostic and molecular diagnostic kits and POC devices by FDA for timely and efficient conduction of diagnostic tests. […] The majority of the literature cited in this paper is collected from guidelines on protocols and other considerations on diagnostic strategies of COVID-19 issued by WHO, CDC, and FDA under emergency authorization. […] Such information holds importance to the health professionals in conducting error-free diagnostic tests and researches in producing better clinical strategies by addressing the limitations associated with the available methods. | 2020-09-14 |
| 32924762 | Patients with hyperglycemia during hospitalization, especially during ICU hospitalizations, often have worse outcomes, even if they do not have a premorbid diagnosis of diabetes. | 2020-09-14 |
| 32924795 | Students in two classes received 8 weeks of face-to-face instruction with five low-tech active learning techniques and then received 6 weeks of emergency remote, online instruction. | 2020-09-14 |
| 32924962 | Tests of the validity of the model and statistical techniques were applied. […] We need improved standardized surveillance techniques to inform leaders when it is safe to open sections of the country; (2) varying public health policies and guidelines unnecessarily result in varying degrees of transmission and outbreaks; and (3) even those states most successful in containing the pandemic continue to see a small but constant stream of new cases daily. | 2020-09-14 |
| 32924965 | The National Reference Laboratory for Respiratory Viruses of the National Public Health Center aimed to carry out a retrospective study of the swab and other samples taken for testing respiratory virus infections between January 1, and April 19, 2020 sent by sentinel physicians within the influenza surveillance for diagnostic purposes. […] For the study, we used swab samples taken weekly by sentinel physicians of the influenza surveillance service, and other samples received for diagnostic purposes. […] Also, of the 551 samples collected for diagnostic reasons of other respiratory viruses, no SARS-CoV-2 positive was found among those taken before March 4. | 2020-09-14 |
| 32925078 | The mental health and illness aspect of COVID-19 are among the most important side effects of this pandemic which requires a national plan for prevention, diagnosis and treatment. | 2020-09-14 |
| 32925396 | We describe the diagnosis, treatment and outcome of a 4-year-old boy with high-risk acute lymphoblastic leukemia and COVID-19. | 2020-09-14 |
| 32925503 | The gastroenterological diagnostic investigations comprised abdominal ultrasound, gastroscopy and endoscopic ultrasound and first revealed no clear cause of these symptoms. […] In an abdominal computed tomography (CT) scan, patchy ground-glass opacities in both lungs were discovered and the following chest CT scan and a virus PCR test revealed the right and surprising diagnosis. | 2020-09-14 |
| 32925588 | Despite advances in techniques, ostomy and surgical-related postoperative complications are prevalent and may impair physical recovery and health quality of life. […] Despite challenges imposed during the COVID-19 pandemic, we were able to manage multiple surgical- and ostomy-related complications using a combination of telecommunication techniques that mitigated the need for routine and urgent postoperative clinic visits, hospital readmission, or unplanned visits to an emergency department. | 2020-09-14 |
| 32925701 | Additional pediatric studies are necessary to gain a broader understanding of COVID-19’s sonographic appearance in this age group and to determine whether POCUS may be helpful to facilitate diagnosis and expedite management decisions. | 2020-09-14 |
| 32925751 | Due to limitations in sensitivity and specificity of current COVID-19 diagnostic studies, cases that trigger high clinical intuition, even with negative serologic and polymerase chain reaction testing results, may necessitate further diagnostic workup to discover the underlying etiology. […] While undergoing diagnostic workup, the patients first 2 sets of COVID 19 reverse transcription-polymerase chain reaction (RT-PCR) were negative while a latter RT-PCR test, as well as serology, were positive, leading to the diagnosis of COVID-19 reinfection or subacute presentation of viral infection with pericardial effusion. […] Due to the possible establishment of pericardial effusions and consecutively tamponade even without any COVID-19 related clinical presentation, it is crucial for clinicians to trust their intuition, conduct the appropriate diagnostic tests, find the underlying diagnosis and prevent the devastating consequences. | 2020-09-14 |
| 32925800 | With the improvement of diagnosis and treatment level in various countries, more and more patients have recovered. | 2020-09-14 |
| 32925832 | Otolaryngologists and associated staff are at high risk for COVID-19 disease transmission based on close contact with mucosal surfaces of the upper aerodigestive tract during diagnostic evaluation and therapeutic procedures. | 2020-09-14 |
| 32926098 | A cohort of 32 hospitalized patients with a confirmed diagnosis of COVID-19 and healthy controls were enrolled. | 2020-09-14 |
| 32926319 | Other key clinical entities were also confirmed and normalized to obtain information on the diagnosis, clinical treatments, laboratory tests, and outcomes of the patients. | 2020-09-14 |
| 32926424 | This study aimed to evaluate the clinical performance of low serum calcium and phosphorus in discriminative diagnosis of the severity of patients with coronavirus disease 2019 (COVID-19). […] Low calcium and low phosphorus could indicate the severity of COVID-19 patients, and may be utilized as promising clinical biomarkers for discriminative diagnosis. | 2020-09-14 |
| 32926425 | The frequency of cells, gene expression of related factors, as well as the secretion levels of cytokines, were measured by flow cytometry, real-time polymerase chain reaction, and enzyme-linked immunosorbent assay techniques, respectively. | 2020-09-14 |
| 32926669 | Diagnostic testing is currently limited in availability, accuracy, and efficiency. […] Lung point-of-care ultrasound can provide valuable data supporting diagnostic and triage decisions surrounding suspected cases of COVID-19. | 2020-09-14 |
| 32926680 | The novel coronavirus disease 2019 (COVID-19) presents a challenge for healthcare providers in terms of diagnosis, management, and triage of cases requiring admission. […] Various risk-stratifying tools and techniques can aid clinicians in identifying COVID-19 patients who can be safely discharged from the ED. | 2020-09-14 |
| 32926682 | The patient underwent further workup and treatment with intravenous corticosteroids with improvement of symptoms and a discharge diagnosis of ATM secondary to SARS-CoV-2. | 2020-09-14 |
| 32926684 | Prompt recognition and diagnosis can minimize the risk of transmission to hospital staff and facilitate initiation of treatment. | 2020-09-14 |
| 32926795 | Hospitals variably implemented system changes, developed tests, and set up diagnostic centers. | 2020-09-14 |
| 32926977 | Likelihood of hospitalization and mortality were compared between groups with and without propensity score matching for confounding factors. 53,511,836 unique patient records were analyzed, of which 32,076 (0.06%) had a CoVid-19-related diagnosis documented starting after January 20, 2020. 214 patients with CoVid-19 were identified with recent TNFi or methotrexate exposure compared to 31,862 patients with CoVid-19 without TNFi or methotrexate exposure. | 2020-09-14 |
| 32927092 | For the analysis of ICU stay or oxygen usage, where the initiating event is potentially an outcome of treatment, standard survival analysis techniques may not be appropriate. | 2020-09-14 |
| 32927229 | For the remaining models, different versions developed include different sets of a patient’s features, with some including information on how the disease is progressing (e.g., diagnosis of pneumonia). | 2020-09-14 |
| 32927291 | Participants who were employed, those with some or completed postsecondary education and those with a chronic illness diagnosis were more likely to adhere to the precautionary behaviours. | 2020-09-14 |
| 32927357 | The aim of the present study was to evaluate the clinical performance of four SARS-CoV-2 immunoassays and their contribution in routine care for the diagnosis of COVID-19, in order to benefit of robust data before their extensive use. […] Serology was complementary to RT-PCR for the diagnosis of COVID-19 at least 14 days after onset of symptoms. | 2020-09-14 |
| 32927419 | The multiple pathological effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and its total novelty, mean that currently a lot of diagnostic and therapeutic tools, established and tentative alike, are needed to treat patients in a timely, effective way. […] In order to make these tools more reliable, faster and more feasible, biological fluid microsampling techniques could provide many advantages. […] In this review, the most important microsampling techniques are considered (dried matrix spots, volumetric absorptive microsampling, microfluidics and capillary microsampling, solid phase microextraction) and their respective advantages and disadvantages laid out. | 2020-09-14 |
| 32927798 | Therefore, the present study aimed to confirm the presence of viable virus in asymptomatic or mildly symptomatic patients in the later phase of the disease, more than two weeks after diagnosis. […] In addition, saliva can be used as a reliable specimen for the diagnosis of SARS-CoV-2 infection. | 2020-09-15 |
| 32928180 | Protective factors were the possibility to work in home office, frequent (indirect) contact with family or friends, the availability of virus-specific information, confidence in the diagnosis capability, and physical activity during the crisis. | 2020-09-15 |
| 32928308 | Techniques that reduce surgical time and thus exposure risk should be considered. | 2020-09-15 |
| 32928323 | From the 483 research papers initially identified, 32 original studies were selected, comprising a total of 17 306 subjects with a laboratory confirmed diagnosis of coronavirus disease 2019. | 2020-09-15 |
| 32928412 | Thus, early diagnosis is crucial to prevent the extensive spread of the disease. […] However, several other faster and accurate assays are being developed for the diagnosis of COVID-19 aiming to control the spread of infection through the identification of patients and immediate isolation. […] In this review, we will discuss the various detection methods of the SARS-CoV-2 virus including the recent developments in immunological assays, amplification techniques as well as biosensors. | 2020-09-15 |
| 32928765 | Traditionally, touch is central to medical practice, physical examination guides diagnosis and informs management. | 2020-09-15 |
| 32929211 | This is a retrospective case-control study of electronic health records (EHRs) data of 73,099,850 unique patients, of whom 12,030 had a diagnosis of COVID-19. […] Patients with a recent diagnosis of SUD (within past year) were at significantly increased risk for COVID-19 (adjusted odds ratio or AOR = 8.699 [8.411-8.997], P < 10-30), an effect that was strongest for individuals with OUD (AOR = 10.244 [9.107-11.524], P < 10-30), followed by individuals with tobacco use disorder (TUD) (AOR = 8.222 ([7.925-8.530], P < 10-30). […] Among patients with recent diagnosis of SUD, African Americans had significantly higher risk of COVID-19 than Caucasians (AOR = 2.173 [2.01-2.349], P < 10-30), with strongest effect for OUD (AOR = 4.162 [3.13-5.533], P < 10-25). | 2020-09-15 |
| 32929416 | We provide suggestions on both clinical diagnosis and treatment strategies for lung cancer to optimize the process, given the urgency of the current circumstances. | 2020-09-15 |
| 32929476 | Their measurement assists in the differential diagnosis of hyperthyroidism and offers accurate and rapid diagnosis of GD. […] A clear trend towards serological diagnosis and medical treatment of GD has emerged. | 2020-09-15 |
| 32929726 | Since the discovery of circulating tumor cells in 1869, technological advances in studying circulating biomarkers from patients’ blood have made the diagnosis of nonhematologic cancers less invasive. | 2020-09-15 |
| 32930583 | However, in cases of rare transcripts or inhibiting contaminants in the sample, an extensive amplification could bias the copy number estimation, leading to quantification errors and false diagnosis. […] Single-molecule techniques may bypass amplification but commonly rely on fluorescence detection and probe hybridization, which introduces noise and limits multiplexing. | 2020-09-15 |
| 32930820 | After a positive diagnosis of COVID-19 and approximately 2 months duration of anosmia, an MRI was performed that showed clear interval olfactory bulb atrophy. […] This diagnostic finding is of prognostic importance and indicates that the olfactory entry point to the brain should be further investigated to improve our understanding of COVID infectious pathophysiology. | 2020-09-15 |
| 32930834 | Combining imaging features with epidemiology history and clinical information could facilitate the early diagnosis of COVID-19 pneumonia. | 2020-09-15 |
| 32931443 | Efficient diagnosis and treatment are crucial to combat the disease. […] Computer-interpretable guidelines (CIGs) can aid the broad global adoption of evidence-based diagnosis and treatment knowledge. […] A CIG for COVID-19 was developed by translating, interpreting, annotating, extracting, and formalizing the Chinese COVID-19 diagnosis and treatment guideline. […] We developed 18 GDL rules to cover the diagnosis and treatment suggestion algorithms in the narrative guideline. | 2020-09-15 |
| 32931637 | Using univariate and multivariate Cox regression models we compared time to severe events and overall survival to an age-matched control cohort of 39 patients with confirmed Covid-19 without a cancer diagnosis. […] In the cancer cohort 29 patients had a diagnosis of a solid tumor, and 10 had a hematological malignancy. […] Major influences on mortality were high IL-6 levels at Covid-19 diagnosis (HR = 6.95, P = .0121) and age ≥ 65 years (HR = 6.22, P = .0156). […] Compared to an age-matched noncancer cohort, we did not observe an association between a cancer diagnosis and a more severe disease course or higher fatality rate in patients with Covid-19. | 2020-09-15 |
| 32932152 | The aim of this study was to assess the diagnostic performance of the GeneFinderTMCOVID-19 Plus RealAmp Kit on the ELITe InGenius sample-to-result platform, which is a commercial nucleic acid amplification test (NAT) targeting genes of SARS-CoV-2. […] The inclusion of the N gene as a third gene target may further increase sensitivity for the diagnosis of COVID-19 in comparison to the national reference method. | 2020-09-15 |
| 32932176 | Pediatric population has been less studied than adult population and prompt diagnosis is challenging due to asymptomatic or mild episodes. […] To establish the most common CXR patterns in children with COVID-19, evaluate interobserver correlation and to discuss the role of imaging techniques in the management of children. […] Imaging techniques have a role in the management of children with known or suspected COVID-19, especially in those with moderate or severe symptoms or with underlying risk factors. | 2020-09-15 |
| 32932252 | All adult and pediatric patients with a diagnosis of a neoplastic or a nonneoplastic hematologic disease who underwent treatment (chemotherapy or immunosuppressive or supportive therapy) during the study period or in the previous 6 months were considered. | 2020-09-15 |
| 32932327 | As postoperative mortality in case of COVID pneumonia is not negligible, meticulous rules (precise triage, safe hospital path, high level of protection for health-care teams, prompt diagnosis of suspicious symptoms) should be strictly followed in patients undergoing CS during COVID pandemic. | 2020-09-15 |
| 32932346 | ICU of Bari Policlinico Academic Hospital (Italy), dedicated to care patients with confirmed diagnosis of novel coronavirus disease 2019. | 2020-09-15 |
| 32932347 | Therapeutic anticoagulation after imaging diagnosis of the first three deep venous thrombosis cases was confirmed; therapeutic anticoagulation as prophylaxis thereafter to all subsequent ICU admissions. […] Full anticoagulation is indicated if the diagnosis is confirmed, and therapeutic anticoagulation should be considered for prophylaxis, as all coronavirus disease 2019 patients are at increased risk. | 2020-09-15 |
| 32932534 | The objective of this study was to review the origin and characteristics of this virus (SARS-CoV-2), symptoms and diagnosis of COVID-19, treatment of people with COVID-19, forms of transmission of the SARS-CoV-2, and precautions in dentistry. […] SARS-CoV-2 articles about the origin and characteristics of this virus (SARS-CoV-2), symptoms and diagnosis of COVID-19, treatment of people with COVID-19, forms of transmission of the SARS-CoV-2, and precautions in dentistry were included. | 2020-09-15 |
| 32932571 | Study of the specific antibodies dynamic characteristics in patients with COVID-19 is very important for the understanding and diagnosis of the disease, research and development of vaccine, and planning of prevention and control strategy. | 2020-09-15 |
| 32932831 | Eight weeks after PCR confirmed diagnosis, a detailed questionnaire, a clinical examination, and laboratory testing, including VITD status, were evaluated. | 2020-09-16 |
| 32933365 | For instance, the dosing scheme proposed for a 70 kg adult with moderate COVID-19 symptoms would be 600 mg upon diagnosis, 400 mg after 12 h, 300 mg after 24 h, 200 mg after 36 h, followed by 200 mg BID for 4 d, followed by 200 mg OD for 5 d. | 2020-09-16 |
| 32933369 | Patients & methods: We reported the influenza-like illness events with diagnosis of COVID-19 within the patient cohort enrolled in the prospective observational multicenter INVIDIa-2 study in the single center of Parma. […] Results: Among 53 patients, eight experienced influenza-like illness during the influenza season 2019/2020, and three of them had diagnosis of COVID-19. | 2020-09-16 |
| 32933383 | Over half report fear of COVID-19 diagnosis and giving the virus to someone else; yet only some switched from smoking to nonsmoking forms of cannabis. | 2020-09-16 |
| 32933464 | Statistical analysis techniques where used to analyze the distribution of the affected cases in a particular state. | 2020-09-16 |
| 32933519 | Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. […] Chest x-ray can be used in diagnosis and follow up in patients with COVID-19 pneumonia. | 2020-09-16 |
| 32933552 | Confirmed diagnosis of SARS-CoV-2 infection (via polymerase chain reaction [PCR] and/or antibody test). | 2020-09-16 |
| 32933917 | This case discusses the presentation and diagnosis of a patient with an acute contained thoracic aortic aneurysm rupture at 38 weeks of gestation, after presenting with throat pain and syncope during the COVID-19 pandemic. […] Diagnosis in this case was finalised with multimodality imaging, including transthoracic echocardiogram, and the patient underwent surgical aortic repair. | 2020-09-16 |
| 32934678 | Rapid and accurate molecular diagnostic technologies are crucial for the screening, isolation, treatment, prevention and control of COVID-19. […] Currently, nucleic acid detection-based techniques and rapid diagnostic tests that detect antigens or antibodies specific to 2019-nCoV infections are the primary diagnostic tools. […] The most effective way to prevent and control COVID-19 is early detection, diagnosis, isolation and treatment. […] In the clinical application of molecular diagnosis technology, it is necessary to combine pathogenic microbiology, immunology and other associated detection technologies, advocate the combination of multiple technologies, determine how they complement each other, enhance practicability and improve the ability of rapid and accurate diagnosis and differential diagnosis of COVID-19. | 2020-09-16 |
| 32934758 | How does one diagnosis affect the other? […] Finally, we addressed the issues of vaccination and diagnostic reliability in the context of coinfection. | 2020-09-16 |
| 32934903 | The only positive diagnostic test was a SARS-CoV-2 test by real-time reverse transcriptase-polymerase chain reaction assay. | 2020-09-16 |
| 32934906 | The diagnosis of pancreatitis was based on laboratory as well as radiological evidence, and all the usual etiologies were ruled out. | 2020-09-16 |
| 32934912 | We report on the first documented cluster of Coronavirus Disease 2019 cases amongst diagnostic laboratory staff and outline some of the initial and ongoing steps that are being implemented to manage and prevent the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in our laboratory. […] On 24 April 2020, three staff members of a tertiary diagnostic laboratory in Groote Schuur Hospital, Cape Town, South Africa, tested positive for SARS-CoV-2. | 2020-09-16 |
| 32934940 | Conclusion: This study highlighted the focused subjects on various aspects of COVID-19 literature such as pathogenesis, epidemiology, transmission, diagnosis, treatment, prevention, and its complications. | 2020-09-16 |
| 32935157 | Patients with clinical and laboratory diagnosis of COVID-19 that required a neurologic consultation or those who presented with neurological problems on admission that led to a diagnosis of SARS-CoV-2 infection during a 2-month period at the peak of the pandemic were included in this study. […] The presenting neurologic manifestations on admission led to the diagnosis of COVID-19 in 14 patients (40%). […] Neurological disturbances represent a significant and severe burden in COVID-19 patients, and they can be the presenting condition that leads to the diagnosis of the viral infection in a high percentage of patients. | 2020-09-16 |
| 32935535 | The diagnosis of SARS-CoV-2 infection presents some limitations. […] RT-PCR in nasopharyngeal swabs is considered the gold standard for the diagnosis, although it can have false negative results. […] A total of 145 hospitalized patients with suspected SARS-Cov2 infection were admitted and in 98 (67.5%) diagnosis was confirmed. […] We have defined a pre-test probability score based on epidemiological and clinical data with a high accuracy for diagnosis of SARS-CoV-2. | 2020-09-16 |
| 32935628 | The presumed low diagnostic sensitivity of upper respiratory specimens for Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) makes it difficult to confirm infection and recommend de-isolation. […] And 43.5% (123/283) of negative RT-PCR results were reversed within 3 weeks of diagnosis. | 2020-09-16 |
| 32935644 | Diagnosis was based on a positive real-time reverse transcription-polymerase chain reaction (RT-PCR) on nasopharyngeal samples. | 2020-09-16 |
| 32935807 | Group 1 included patients whose diagnosis of COVID-19 was confirmed by polymerase chain reaction (PCR). | 2020-09-16 |
| 32935831 | The pandemic of coronavirus disease 2019 (COVID-19) urgently calls for more sensitive molecular diagnosis to improve sensitivity of current viral nuclear acid detection. […] Lastly, AP-PCR analysis of 306 confirmed and convalescent cases revealed prolonged presence of viral loading for >20 days after the first positive diagnosis. | 2020-09-16 |
| 32935872 | Convalescent plasma units from 47 individuals with a history of nonsevere COVID-19 were assessed for antigen-binding activity of using three clinical diagnostic serology assays (Beckman, DiaSorin, and Roche) with different SARS-CoV-2 targets. | 2020-09-16 |
| 32935915 | We aimed to investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID-19. […] Further research is required to establish the true diagnostic value of these symptoms and efficacy as screening tools for COVID-19 patients. | 2020-09-16 |
| 32935928 | Clinicians need to pay close attention to cardiovascular complications during the diagnosis and treatment of patients with COVID-19 to reduce patient mortality. | 2020-09-16 |
| 32936034 | Materials and Methods: All patients with a proven diagnosis of COVID-19 and PM between March 18, 2020 and May 5, 2020 were identified through hospital records. | 2020-09-16 |
| 32936047 | This review presents literature that highlights saliva’s utility as a biofluid in the diagnosis and monitoring of COVID-19. […] Studies were eligible for inclusion if they assessed the potential diagnostic value and/or other discriminatory properties of biological markers in the saliva of patients with COVID-19. […] Clinical studies with larger patient populations that measure recordings at different stages during the disease are still necessary to confirm the accuracy of COVID-19 diagnosis with saliva. […] Nevertheless, the utility of saliva as a diagnostic tool opens the possibility of using rapid and less invasive diagnostic strategies by targeting bioanalytes rather than the pathogen. | 2020-09-16 |
| 32936214 | COVID-19 was diagnosed according to the fifth edition of Chinese COVID-19 diagnostic guidelines. | 2020-09-16 |
| 32936318 | Thus, pediatricians need to be aware of such atypical presentations resembling KD for early diagnosis of COVID-19. | 2020-09-16 |
| 32936372 | In the remaining two, it was not possible to confirm the presence of COVID-19 with RT-PCR, although in one of them, PET/CT allowed an early diagnosis of a lung infection related to a bacterial pneumonic infection that was promptly and adequately treated with antibiotics. […] In these patients, PET/CT allows an early diagnosis of COVID-19. | 2020-09-16 |
| 32936471 | The SARS-CoV-2 pandemic has led to an unprecedented demand for diagnostic tests. | 2020-09-16 |
| 32936553 | Telemedicine contributed to the triage and follow-up of patients with a suspected or confirmed diagnosis of COVID-19, as well as to the coordination of different healthcare actors in the patient’s trajectory. | 2020-09-16 |
| 32936777 | By using a broad set of NLP techniques and analyzing a baseline of prepandemic posts, we uncovered patterns of how specific mental health problems manifest in language, identified at-risk users, and revealed the distribution of concerns across Reddit, which could help provide better resources to its millions of users. | 2020-09-16 |
| 32937590 | The outbreak of the highly contagious and deadly severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19), has posed a serious threat to public health across the globe, calling for the development of effective diagnostic markers and therapeutics. […] Here, we report a highly reliable severity diagnostic biomarker, acetylated 676th lysine transforming growth factor-beta-induced protein (TGFBIp K676Ac). […] The increased level of TGFBIp K676Ac in ICU patients suggests the promise of this protein as a reliable severity diagnostic biomarker for severe SARS-CoV-2 disease. | 2020-09-16 |
| 32937868 | Characterization of these viral variants can provide precious insights on viral pathogenesis and can be valuable for diagnostic and drug development approaches. | 2020-09-17 |
| 32938229 | Not only India has high burden of cancer, but the majority (75-80%) of patients have advanced disease at the time of diagnosis. | 2020-09-17 |
| 32938445 | Clinicians should be vigilant about the diagnosis and treatment of this complication. | 2020-09-17 |
| 32938502 | Based on the estimated parameter values, we performed numerical simulations to predict the epidemic trend and evaluate the impact of contact limitation, detection and diagnosis, and individual behavior change due to media coverage on the epidemic. | 2020-09-17 |
| 32938604 | Studies had to report the prevalence of sociodemographic characteristics, symptoms and comorbidities specifically in adults with a diagnosis of infection by SARS-CoV-2. | 2020-09-17 |
| 32939188 | While the application of CRISPR in human genome editing and diagnosis needs to be researched more fully, and any potential side effects or ambiguities resolved, CRISPR has already shown its capacity in an astonishing variety of applications related to genome editing and genetic engineering. […] One of its most currently relevant applications is in diagnosis of infectious and non-infectious diseases. […] Diagnostic CRISPR systems are most often derived from types II, V, and VI. […] Diagnostic tests using Cas12 and Cas13 enzymes have already been developed for detection of the emerging SARS-CoV-2 virus. […] Additionally, CRISPR diagnostic tests can be performed using simple reagents and paper-based lateral flow assays, which can potentially reduce laboratory and patient costs significantly. […] The application of these systems in medical diagnostics with emphasis on the diagnosis of COVID-19 will be discussed. | 2020-09-17 |
| 32939324 | This is caused by the paucity of in-depth knowledge of the risk factors for severe COVID-19, insufficient diagnostic tools for the detection of SARS-CoV-2, as well as the absence of specific and effective drug treatments. | 2020-09-17 |
| 32939917 | This was an online survey for caregivers of individuals with (1) a genetic diagnosis and (2) a neurodevelopmental diagnosis, including developmental delay, intellectual disability, autism spectrum disorder or epilepsy. | 2020-09-17 |
| 32940134 | In silico techniques can accelerate the drug development process. | 2020-09-17 |
| 32940188 | The diagnosis, follow-up, and treatment methods of IIH during the COVID-19 pandemic period are reviewed. […] Diagnosis and follow-up of papilledema due to IIH during the COVID-19 pandemic can be facilitated by nonmydriatic fundus photography and optical coherence tomography. […] Certain precautions during the diagnosis and management of this condition could be taken that may allow appropriate care to be delivered to these patients while minimizing the risk of coronavirus infection. | 2020-09-17 |
| 32940409 | After exclusion of trauma patients, no statistical difference in discharge diagnosis was found. | 2020-09-17 |
| 32940547 | We found high diagnostic sensitivities (%, 95% confidence interval [CI]) for the Roche Test (97.4%, 93.4-99.0%), Abbott Test (94.0%, 89.1-96.8%), Wondfo Test (91.4%, 85.8-94.9%), ASK Test (97.4%, 93.4-99.0%), and Dynamiker Test (90.1%, 84.3-94.0%) after >21 days of symptom onset. […] Meanwhile, the diagnostic specificity was 99.0% (95% CI, 96.3-99.7%) for the Roche Test, 97.9% (95% CI, 94.8-99.2%) for the Abbott Test, and 100.0% (95% CI, 98.1-100.0%) for the three LFIAs. […] Our data suggested that understanding the dynamic antibody response after COVID-19 infection and performance characteristics of different serological test are crucial for the appropriate interpretation of serological test result for the diagnosis and risk assessment of patient with COVID-19 infection. | 2020-09-17 |
| 32941351 | It discusses research from diagnosis and beyond, to patient-team communication with a particular focus on medical trials, adherence and living with CFTR modulators. […] The impact of the diagnosis on parents is immense and the complexity of treatment now and in the future, are a challenge for both parents and teams. | 2020-09-17 |
| 32941374 | During the COVID-19 emergency period, the 2-week prevalence of symptoms consistent with a diagnosis of generalized anxiety disorder and depression was 18.2% and 21.6%, respectively, among female professional footballers and 15.5% and 12.9%, respectively, among male players. | 2020-09-17 |
| 32941461 | Among 381 patients with symptoms of COVID-19 who went to the hospital for a diagnostic, 143 patients were RT-PCR negative. | 2020-09-17 |
| 32942143 | To prevent the spread of disease and protect human populations, rapid point-of-care (POC) molecular diagnosis of human and plant diseases play an increasingly crucial role. […] Nucleic acid-based molecular diagnosis reveals valuable information at the genomic level about the identity of the disease-causing pathogens and their pathogenesis, which help researchers, healthcare professionals, and patients to detect the presence of pathogens, track the spread of disease, and guide treatment more efficiently. […] A typical nucleic acid-based diagnostic test consists of three major steps: nucleic acid extraction, amplification, and amplicon detection. […] To perform rapid molecular diagnosis in resource-limited settings, simpler and instrument-free nucleic acid extraction techniques are required to improve the speed of field detection with minimal human intervention. […] The integration of these rapid nucleic acid preparation methods with miniaturized assay and sensor technologies would pave the road for the “sample-in-result-out” diagnosis of human and plant diseases, especially in remote or resource-limited settings. | 2020-09-17 |
| 32942178 | The COVID-19 pandemic has highlighted problems in evaluating the epidemiological scope of the disease using classical surveillance approaches, due to a lack of diagnostic capacity, and their application to only a small proportion of the population. | 2020-09-17 |
| 32942274 | We report the clinicopathologic findings from 32 autopsy studies conducted on patients who died of COVID-19 including routine gross and microscopic examination with applicable special and immunohistochemical staining techniques. | 2020-09-17 |
| 32942316 | We evaluated whether the pandemic has impacted the appropriateness and diagnostic yield of fast-track endoscopic procedures in comparison with those performed in 2019. […] Both appropriate referral and diagnostic yield increased in 2020 and it regarded both upper and lower endoscopy. […] The high level of inappropriate endoscopic referral registered in 2019 has significantly improved during the COVID-19 outbreak with an increase in the diagnostic yield. | 2020-09-17 |
| 32942647 | Younger individuals (OR = 1.58-3.58), those that felt unsafe (OR = 1.75-2.92), with a previous diagnosis of mental health (OR = 1.72-2.64) and/or had general health problems before the pandemic (OR = 1.17-1.51), who noticed changes in their mental state due to the pandemic context (OR = 2.53-9.07), and excessively exposed to the news (OR = 1.19-2.18) were at increased risk of developing symptoms. | 2020-09-18 |
| 32942698 | ED attendance reduced by 27-62% across all categories of diagnosis in the Delay phase and remained significantly below prior year levels as the country began Phase One of Reopening, with an incident rate ratio (IRR) of 0.58. | 2020-09-18 |
| 32942785 | The reopening of America and restarting of interventional techniques and elective surgical procedures has started. […] Our goal is to restore the opportunity to receive appropriate care for our patients who may benefit from interventional techniques. | 2020-09-18 |
| 32942790 | It is also important to explore the current state of knowledge about using allogenic instead of autologous blood as well as emerging techniques to eliminate the coronavirus from the blood. | 2020-09-18 |
| 32942792 | Since the late 1940s, corticosteroids have been a mainstay class of agents in multiple interventional techniques and intra-articular injections. | 2020-09-18 |
| 32942794 | Technological interventions such as telemedicine visits with patients, virtual meetings with colleagues, and online interviews have been introduced, and many trainees are “techno-omnivores” who are comfortable using a variety of technology platforms and techniques. | 2020-09-18 |
| 32942812 | To describe and illustrate musculoskeletal and neurologic examination techniques that can be used effectively in telemedicine. | 2020-09-18 |
| 32943140 | There were no evident risk factors for pulmonary thromboembolism, the patient had a Wells’ score of zero, and the diagnosis only became evident after repeated CT pulmonary angiographies. | 2020-09-18 |
| 32943211 | The literature described psychiatric sequelae of the coronavirus and related public health interventions through cross-sectional surveys among different populations; no studies include diagnostic or functional impairment data. | 2020-09-18 |
| 32943371 | Histiocytic disorders are an exceptionally rare group of diseases with diverse manifestations and a paucity of approved treatments, thereby leading to various challenges in their diagnosis and management. | 2020-09-18 |
| 32943372 | Patients were additionally queried regarding their anxiety level related to COVID-19 and associated implications for their cancer diagnosis. | 2020-09-18 |
| 32943416 | Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction testing, but the sensitivity is limited. […] We evaluated CTA as a potential COVID-19 diagnostic imaging biomarker. […] We evaluated the reliability and accuracy of candidate diagnostic imaging biomarkers. […] Ground-glass opacification had high interrater reliability (Fleiss κ = 0.81; 95% CI, 0.68-0.95) and, compared with reverse-transcriptase polymerase chain reaction, had good diagnostic performance (sensitivity, 75% [95% CI, 56-87]; specificity, 81% [95% CI, 71-88]; OR = 11.65 [95% CI, 4.14-32.78]; P < .001) on multivariate analysis. […] In contrast, all other contemporaneous demographic, clinical, and imaging features available at CTA were not diagnostic for COVID-19. […] We identified a simple, reliable, and accurate COVID-19 diagnostic and prognostic imaging biomarker obtained from CTA lung apices: the presence or absence of ground-glass opacification. | 2020-09-18 |
| 32943474 | Controversies of renin-angiotensin-aldosterone system inhibitors usage in patients with COVID-19 and meticulous handling of case with acute coronary syndrome categorically stresses cardiologists to bust the myths hovering around and set a standard guideline to counterfeit the fatality with timely diagnosis and treatment of COVID-19-induced ACI. […] In this review, we sought to summarise the current evidence of COVID-19-associated cardiac injury and suggest the implications for its proper diagnosis and treatment. | 2020-09-18 |
| 32943533 | Median age at diagnosis was 5 days. | 2020-09-18 |
| 32943831 | Demographics, diagnosis, intravitreal injection history, medical history, ophthalmic examinations and optical coherence tomography data were collected and analyzed. | 2020-09-18 |
| 32944044 | Fifty adult patients with flu-like symptoms and radiologic findings compatible with atypical pneumonia who were admitted to the infectious diseases ward of Imam Khomeini Hospital Complex, Tehran, Iran, with a clinical diagnosis of COVID-19 from February 28 to April 27 of 2020 were randomly selected and entered in our study. | 2020-09-18 |
| 32944565 | Till our knowledge is improved, the most important intervention in the treatment of critically ill patients with COVID-19 seems to be the level of standard care and appropriate and early diagnosis and treatment. […] It seems that each center should have its protocol on the management of critically ill COVID-19 patients regarding prevention, diagnosis, and treatment. | 2020-09-18 |
| 32944809 | Several diagnostic methods are reported for detecting the coronavirus in clinical, research, and public health laboratories. […] A diagnostic test during the pandemic should help make an appropriate clinical decision in a short period of time. […] Recently reported diagnostic methods for SARS-CoV-2 have varying throughput, batching capacity, requirement of infrastructure setting, analytical performance, and turnaround times ranging from a few minutes to several hours. […] These factors should be considered while selecting a reliable and rapid diagnostic method to help make an appropriate decision and prompt public health interventions. […] This paper reviews recent SARS-CoV-2 diagnostic methods published in journals and reports released by regulatory agencies. | 2020-09-18 |
| 32945156 | Week 13 had the highest diagnosis performance (39.0%). […] The RT-PCR has a high diagnostic performance in the phases of highest contagiousness and / or transmissibility of the virus. | 2020-09-18 |
| 32945214 | RT-PCR assays are diagnosis gold standard; however, they can lead to false-negative results. | 2020-09-18 |
| 32945279 | Imaging examination has become the indispensable means not only in the early detection and diagnosis but also in monitoring the clinical course, evaluating the disease severity, and may be presented as an important warning signal preceding the negative RT-PCR test results. | 2020-09-18 |
| 32945634 | Furthermore, the authors of this paper consider it appropriate to make suggestions and develop interventionist techniques regarding the interface with the patient starting from the initial consultation. | 2020-09-18 |
| 32945644 | Chest high resolution computed tomography (HRCT) is an essential tool in diagnosis and management of the disease. | 2020-09-18 |
| 32945944 | With regard to these 13 patients, the median age at coronavirus disease (COVID-19) diagnosis was 68 years (range 28-76 years) and 8 (61.5%) were female. | 2020-09-18 |
| 32946100 | Secondary outcomes of this study were patient complaints, diagnosis and treatments, treatment rejection rate, triage category data, the effects of age and gender, and the hospitalization rate. | 2020-09-18 |
| 32946149 | The similar clinical manifestations shared by Covid-19 and dengue fever have raised concerns, especially in dengue-endemic countries with limited resources, leading to diagnostic challenges. | 2020-09-18 |
| 32946270 | Diagnostic and intervention approaches for such impairments are discussed. | 2020-09-18 |
| 32946413 | AI was applied to COVID-19 in four areas: diagnosis, public health, clinical decision-making, and therapeutics. | 2020-09-18 |
| 32946795 | Serologic tests are one of the available diagnostic tools in COVID-19. […] Unfortunately, due to the limited availability of commercial tests and the lack of reliable trials establishing the sensitivity and specificity of the diagnostic method, the clinical application of the test needs to be precisely determined. […] In this paper, we discuss the utility of anti-SARS-CoV-2 serology testing in a clinical setting and propose diagnostic algorithms that include serological tests in patients with confirmed or suspected COVID-19. | 2020-09-18 |
| 32946801 | Multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease (COVID-19) is a rare and challenging diagnosis requiring early treatment. […] The diagnostic criteria involve clinical, laboratory, and complementary tests. […] This review aims to draw pediatrician attention to this diagnosis, suggesting early treatment strategies, and proposing a pediatric emergency care flowchart. | 2020-09-18 |
| 32947089 | Multi-organ involvement, delay in the diagnosis, incomplete work up and start of therapy, were registered in 50% of cases with a GBS-Disability scale ≥4 at follow-up evaluation. […] In not-COVID-19 related GBS, main problem was diagnostic delay. | 2020-09-18 |
| 32947341 | Attention should be paid to the disease and population characteristics of patients with cleft lip with/without palate during diagnosis and treatment. | 2020-09-18 |
| 32947412 | A literature review of techniques was performed, enabling multiple transplants to be derived from a single donor and simulation of a model to quantify the number of corneas potentially saved. | 2020-09-18 |
| 32947588 | Diagnostic Level IV. | 2020-09-18 |
| 32947590 | From February 21, 2020, to March 23, 2020, 20 patients with a fracture and a diagnosis of COVID-19 were hospitalized. | 2020-09-18 |
| 32948121 | However, Differential diagnosis remains difficult for suspected cases of COVID-19 and need to be improved to reduce misdiagnosis. […] Multiplex PCR nucleic acid testing helped differential diagnosis for suspected COVID-19 cases. | 2020-09-19 |
| 32948378 | Various diagnostic platforms including of serological, molecular and other advanced tools and techniques have been designed and developed for rapid detection of SARS-CoV-2 and each has its own merits and demerits. […] Molecular assays such as real-time reverse transcriptase polymerase chain reaction (rRT-PCR) has been used worldwide for diagnosis of COVID-19. […] Here, we present an overview on advances in diagnosis of COVID-19 and details the issues associated with biosafety procedures and potential safety precautions to be followed during collection, transportation, and processing of COVID-19 samples for laboratory diagnosis so as to avoid virus infection. | 2020-09-19 |
| 32948855 | The control of viral outbreaks requires nucleic acid diagnostic tests that are sensitive, simple and fast. | 2020-09-19 |
| 32948989 | These issues are best addressed through the application of currently available medical technology and enhanced training in advanced oncoplastic techniques, which extend the limits of breast conservation. | 2020-09-19 |
| 32949058 | We collected all the online consultation information in Dept. of Paediatric dentistry, School & Hospital of Stomatology, Wuhan University, from 2 February to 31 March 2020, and extracted the information of age, gender, reason for consultation, description of symptom, and preliminary diagnosis of the children. | 2020-09-19 |
| 32949098 | Eight patients (31%) were hospitalized at time of diagnosis, 3 of whom were already admitted for unrelated problems. | 2020-09-19 |
| 32949449 | The latter patient had also ENA SS-A positive and RF positivity, confirmed at a second check, so as to allow us to make a diagnosis of connective tissue disease. | 2020-09-19 |
| 32949574 | We performed NVC in patients with a confirmed diagnosis of COVID-19 pneumonia. | 2020-09-19 |
| 32949776 | To investigate the pattern of tuberculosis (TB) care initiation and risk factors for TB diagnostic delay in The Gambia. […] Diagnostic delay was defined as >21 days from onset of at least one symptom suggestive of pTB to diagnosis. […] Logistic regression analyses were used to investigate risk factors for diagnostic delay. […] 110/216 (50.9%) initiated care-seeking in the formal and informal private sector, and 181/216 (83.8%) had TB diagnostic delay. […] The median (IQR) duration from onset of symptoms to TB diagnosis was 34 (28-56) days. […] Age groups 18-29 years (aOR 3.2; 95% CI 1.2 - 8.8 [p = 0.02]) and 30-49 years (aOR 5.1; 95% CI 1.6 - 16.2 [p = 0.006]), and being employed (aOR 4.2; 95% CI 1.7- 10.5 [p = 0.002]) were independent risk factors for TB diagnostic delay. […] There is considerable TB diagnostic delay in The Gambia and this is likely to be worsened by the COVID-19 pandemic. | 2020-09-19 |
| 32949888 | However, we used more techniques and also included Angiotensin converting enzyme 2 (ACE2) (a SARS-CoV receptor, possibly the viral entry point in alveolar lung cells) and the immune system, as cytokine storm is essential in the late phase. | 2020-09-19 |
| 32950066 | Diagnosis of a mental illness was not associated with increased likelihood of testing positive for SARS-CoV-2. | 2020-09-20 |
| 32950309 | One of the most widely studied coagulation markers in Covid-19 is D-dimer (DD), raised levels of which have prognostic implications, although the best cut-off point for the diagnosis of venous thromboembolism (VTE) in this population has not been clarified, nor has its usefulness in determining the intensity of thromboprophylaxis required in these patients. […] Until sufficiently robust information (preferably from well-designed clinical trials) is available, the recommendations of clinical practice guidelines for the prophylaxis, diagnosis and treatment of VTE should be followed in Covid-19 patients. | 2020-09-20 |
| 32950466 | Based on the pathophysiological involvement of the pituitary-thyroid axis, the current review discusses the diagnosis of abnormal thyroid function test, and the management of patients presenting with thyrotoxicosis, thyroid-associated orbitopathy and hypothyroidism in the context of SARS-CoV-2 infection. | 2020-09-20 |
| 32950697 | The Nucleocapsid (N) and Spike (S) are highly immunogenic structural proteins and most commercial COVID-19 diagnostic assays target these proteins. […] It is necessary to continue with the genomic surveillance of S and N proteins during the SARS-CoV-2 pandemic as this information can be useful for developing vaccines, therapeutics and diagnostic tests. | 2020-09-20 |
| 32950740 | We report two cases of HIV positive patients with SARS-CoV-2 infection and a recent diagnosis of opportunistic infections of central nervous system (CNS). | 2020-09-20 |
| 32950749 | We conducted a multi-center, observational cohort study across 21 institutions in the United States (US) of adult patients with CLD and laboratory-confirmed diagnosis of COVID-19 between March 1, 2020 and May 30, 2020. | 2020-09-20 |
| 32951064 | Application to reverse-transcriptase qPCR measurements of a SARS-CoV-2 RNA construct points to the usefulness of this approach for improving confidence and reducing limits of detection in diagnostic testing of emerging diseases. | 2020-09-20 |
| 32951147 | We present a case of a 47-year-old male with no known comorbidity, who accidentally swallowed a portion of a naso-pharyngeal swab half-broken during the second diagnostic test for SARS-CoV-2. | 2020-09-20 |
| 32951316 | Studying the changes of electrocardiogram is of great significance for the diagnosis of patients with COVID-19. […] ST-T changes, sinus tachycardia, and atrial fibrillation are with great significance in the diagnosis of the severity, myocardia injury, and cardiac insufficiency of COVID-19 patients. | 2020-09-20 |
| 32952079 | A total of 148 patients with a diagnosis of ACS were admitted during that period of time. | 2020-09-21 |
| 32952101 | In this article, we will review the role of non-contrast chest computed tomography in the diagnosis, follow-up and prognosis of patients affected by COVID-19 pneumonia with a detailed description of the imaging findings that may be encountered. […] Finally, we will describe more advanced applications of CT in the differential diagnosis of myocardial injury with an emphasis on ruling out acute coronary syndrome and myocarditis. | 2020-09-21 |
| 32952121 | The remaining kits use five molecular diagnostic technologies different from RT-qPCR. […] This article reviews the principles, reaction time, advantages and disadvantages of above 15 detection kits, in order to provide references for rapid screening, diagnosis, prevention and control of COVID-19 and similar infectious diseases. | 2020-09-21 |
| 32952210 | In addition, we observe that the aerosol generation can be affected by the changing dynamic level, articulation pattern, the normal respiratory behaviors of individuals, and even the usage of some special techniques during the instrument play. […] However, such effects vary substantially for different types of instrument, depending on specific breathing techniques as well as the tube structure and inlet design of the instrument. | 2020-09-21 |
| 32952300 | Thus, developing a rapid, accurate, and easy-to-implement diagnostic system for SARS-CoV-2 is crucial for controlling infection sources and monitoring illness progression. | 2020-09-21 |
| 32952517 | Therefore, the Saudi Lymphoma Group has decided to provide clinical practice guidelines for the diagnosis, management and follow-up of patients with various types of lymphoma during the COVID-19 pandemic. | 2020-09-21 |
| 32952711 | Different modelling techniques have been used to predict and simulate the spread of COVID-19, but they have not always been useful for epidemiologists and decision-makers. | 2020-09-21 |
| 32952967 | The availability of new diagnostic tools, including Polymerase Chain Reaction and nucleotide sequencing has significantly modified the classification of intracellular bacteria, including the order Rickettsiales with more and more new Rickettsia species recognized as human pathogens. […] Recently, due to the spread of SARS-CoV-2 infection, the differential diagnosis with COVID-19 is of crucial importance. […] The correct understanding of the clinical features, diagnostic tools, and proper treatment can assist clinicians in the management of Rickettsioses in the Mediterranean area. | 2020-09-21 |
| 32953123 | Rapid and early diagnosis of COVID-19 is a challenging issue for physicians and other healthcare personnel. | 2020-09-21 |
| 32953275 | We established ELISA-based immunoassays using locally produced antigens when New Zealand went into a nationwide lockdown and the supply chain of diagnostic reagents was a widely held domestic concern. | 2020-09-21 |
| 32953353 | COVID-19 should be suspected in patients presenting with neurological abnormalities and should be included in the differential diagnosis to prevent further virus transmission. | 2020-09-21 |
| 32953445 | Herein, we review the origin, symptoms, diagnostic tests, and progress of the disease and possible actions of authorities which would be effective in similar pandemics in the future. […] Efforts should be taken by health authorities for preparing the world for future epidemic/pandemic in terms of developing advanced screening strategies in the borders and diagnostic strategies for early identification of infected cases. | 2020-09-21 |
| 32953455 | Diagnosis of MIS-C related to COVID-19 was established by clinical features, elevated inflammatory markers, and positive SARS-COV 2 immunoglobulin G. […] We encourage all clinicians especially who practice adult medicine to be familiar with signs and symptoms of MIS-C to avoid delayed diagnosis and complications. | 2020-09-21 |
| 32953523 | Radiological manifestations of coronavirus disease 2019 (COVID-19) featured ground-glass opacities (GGOs), especially in the early stage, which might create confusion in differential diagnosis with early lung cancer. […] The imaging characteristics should be fully understood and combined with epidemiological history, pathogen detection, laboratory tests, short-term CT reexamination, and pathological results to aid differential diagnosis. | 2020-09-21 |
| 32953632 | Therefore contingency plans are required for dealing with patients in outpatient clinics, and while performing diagnostic endoscopies, minor procedures in OPD and surgeries in operating rooms. | 2020-09-21 |
| 32953735 | Chest CT has been found to play an important role in the diagnosis and management of COVID-19. | 2020-09-21 |
| 32953843 | Our paper intends to examine the available recommendations, complexities in diagnosis and management when dealing with patients with ADs amidst the COVID-19 crisis. | 2020-09-21 |
| 32953852 | The Diagnosis and Treatment Guidelines of New Coronavirus Pneumonia (7th Edition) includes tocilizumab as a recommended drug for immunotherapy in severe and critical COVID-19 patients. | 2020-09-21 |
| 32953870 | This case report of the diagnosis and treatment of an elderly patient with 2019-nCoV pneumonia complicated by acute exacerbation of chronic obstructive pulmonary disease in Gansu Province aims to provide a better reference for the treatment of patients in the future. | 2020-09-21 |
| 32953970 | Besides this, doctors can also carry out the diagnosis of ailments using the data collected remotely from the patient. | 2020-09-21 |
| 32953971 | Early detection and diagnosis are critical factors to control the COVID-19 spreading. […] A number of deep learning-based methodologies have been recently proposed for COVID-19 screening in CT scans as a tool to automate and help with the diagnosis. | 2020-09-21 |
| 32954173 | The aim of this study is to establish a new method with high sensitivity, accuracy, and stability for the determination of human IgG and then expand it to analyze severe acute respiratory syndrome corona virus 2 (SARS-CoV-2)-specific IgM and IgG, which is of great significance for the screening and diagnosis of COVID-19. | 2020-09-21 |
| 32954211 | TTE may be a helpful tool for cardiac performance evaluation and diagnosis not only in supine or anterolateral positioning like in echocardiographic lab, but also in subjects admitted to ICU due to ARDS needing of mechanical ventilation in prone positioning. | 2020-09-21 |
| 32954369 | The diagnostic platforms described can be easily adapted by basic science research laboratories for SARS-CoV-2 diagnostic testing with relatively short turnaround time. | 2020-09-21 |
| 32954445 | As a result, acute stroke care suffered from a shortage of services and delays in time-dependent treatments and diagnostic work-up. | 2020-09-21 |
| 32954488 | Finally, an intriguing question to the dermatologic society was whether skin changes during COVID-19 infection exist and what could be their diagnostic or prognostic value. | 2020-09-21 |
| 32954601 | This study analyzed the clinical and laboratory results of 27 patients with real-time polymerase chain reaction (RT-PCR)-confirmed COVID-19 and 25 patients with a suspected COVID-19 diagnosis based on their symptoms and chest computed tomography (CT) findings. | 2020-09-21 |
| 32954746 | Viral nucleic acid test of SARS-CoV-2 can provide direct evidence for rapid diagnosis, disease course monitoring, and therapeutic efficacy. | 2020-09-21 |
| 32954769 | All three patients died shortly after diagnosis. | 2020-09-21 |
| 32955466 | MMC residents with pre-SARS-CoV-2 accumulation of misfolded proteins diagnostic of AD and PD and metal-rich, magnetic nanoparticles damaging key neural organelles are an ideal host for neurotrophic SARS-CoV-2 RNA virus invading the body through the same portals damaged by nanoparticles: nasal olfactory epithelium, the gastrointestinal tract, and the alveolar-capillary portal. | 2020-09-21 |
| 32955470 | Through mitigation of sedentary behavior and adoption of the techniques described herein, LBP can be decreased and, in some cases, cured. | 2020-09-21 |
| 32955471 | The problem needs both a diagnosis and robust treatment in order to have better outcomes at the individual, organisational and national levels. | 2020-09-21 |
| 32955902 | They proceed in accordance with the current guidelines of the government of each country as well as with the valid standards and preventive, diagnostic and therapeutic procedures for COVID-19. | 2020-09-21 |
| 32956181 | Esophagogastroduodenoscopy is still necessary for diagnosis in children with lower title. […] We aimed to analyze the feasibility and accuracy of a biopsy-free approach in suspected celiac disease children with TGA-IgA values <10 ULN to facilitate the diagnostic process by avoiding endoscopy. […] In this study cohort, we retrospectively analyzed all biopsy-confirmed diagnosis of celiac disease in our center (between 2014 and 2019). […] Mucosal atrophy and resolution of symptoms after gluten-free diet (GFD) were considered to confirm initial diagnosis. | 2020-09-21 |
| 32956447 | Recently, Nachtigall and colleagues reported the development of a MALDI-MS method for the diagnosis of SARS-CoV-2 infection (1). | 2020-09-21 |
| 32956612 | Using tuberculosis (TB) molecular diagnostic infrastructure, which has substantially expanded worldwide in recent years, for COVID-19 case-finding might be warranted. […] We analyze the potential of using TB diagnostic and research infrastructures for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. […] We conclude that diagnostic infrastructures for TB can in principle be leveraged to scale-up SARS-CoV-2 testing, in particular in resource-poor settings. […] However, fundamental principles of quality management must be followed for both TB and SARS-CoV-2 testing to ensure valid results and to minimize biosafety hazards, and the continuity of TB diagnostic services must be guaranteed at all times. | 2020-09-21 |
| 32956703 | While the diagnosis of SARS-CoV-2 infection is primarily based on detection of viral RNA, the detection of SARS-CoV-2 antibodies is useful for assessing past prevalence of the disease, and in corroborating a current infection in challenging cases. […] Diagnostic specificity and sensitivity of the IgG and IgM ELISA assays were tested using samples confirmed to be negative or positive for COVID-19 by RT-PCR. | 2020-09-21 |
| 32956787 | Median delay between onset of symptoms and diagnosis was 4.39 days. | 2020-09-21 |
| 32956989 | Low serum 25(OH)D levels (p = 0.005) and MDD diagnosis (p = 0.001) specifically predicted the severity of psychological distress. […] Low serum 25(OH)D levels and MDD diagnosis predicted an increased vulnerability to the stressful impact of the COVID-19 outbreak. | 2020-09-21 |
| 32957032 | Growing evidence of neurologic involvement seen in COVID-19 infection necessitates the pooling of neurodiagnostic findings like electroencephalography (EEG) that may guide clinical management. | 2020-09-21 |
| 32957066 | Biomarker analysis may help to assist diagnosis and classification of stress-related diseases and therefore support therapeutical decisions. | 2020-09-21 |
| 32957073 | Rapid and accurate diagnosis is crucial for successful outbreak containment. […] During the current coronavirus disease 2019 (COVID-19) public health emergency, the gold standard for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis is the detection of viral RNA. […] Additional diagnostic methods õenabling the detection of current or past SARS-CoV-2 infection would be highly beneficial. […] Diagnostic performances were assessed according to days after symptom onset (dso) and the antigenic format used by manufacturers. | 2020-09-21 |
| 32957139 | In addition, critical considerations regarding the choice of sedative agents should be given to factors such as age, medical versus operative diagnosis, and cardiovascular status. | 2020-09-21 |
| 32957746 | Retrospective study whereby flu diagnosis and lineage analysis were determined by RT-PCR. | 2020-09-22 |
| 32957928 | Therefore, knowing the epidemiological patterns of common respiratory viruses may be valuable to improve the diagnostic and therapeutic efficacy of patients with suspected COVID-19, especially in Southwest China (a mild epidemic area). | 2020-09-22 |
| 32958554 | The diagnosis of GBS was made through cerebrospinal fluid analysis and she was successfully treated with intravenous immunoglobulin administration. | 2020-09-22 |
| 32958971 | COVID-19 is extremely contagious and quickly spreading globally making its early diagnosis of paramount importance. […] Early diagnosis of COVID-19 enables health care professionals and government authorities to break the chain of transition and flatten the epidemic curve. […] The common type of COVID-19 diagnosis test, however, requires specific equipment and has relatively low sensitivity. […] Overlap with other lung infections makes human-centered diagnosis of COVID-19 challenging. […] Consequently, there has been an urgent surge of interest to develop Deep Neural Network (DNN)-based diagnosis solutions, mainly based on Convolutional Neural Networks (CNNs), to facilitate identification of positive COVID-19 cases. […] To potentially and further improve diagnosis capabilities of the COVID-CAPS, pre-training and transfer learning are utilized based on a new dataset constructed from an external dataset of X-ray images. | 2020-09-22 |
| 32958973 | Utilizing web scraping techniques to extract data from different online sources to determine the probable transmission rate in Tamilnadu from the rest of the Indian states. | 2020-09-22 |
| 32959008 | A high degree of clinical suspicion and thorough evaluation helps in the diagnosis of COVID-19 and related complications. | 2020-09-22 |
| 32959015 | Data collection focused on demographics and exposure epidemiology, prior medical history and medications, signs and symptoms, diagnostic test results, interventions, clinical outcomes, and complications. | 2020-09-22 |
| 32959017 | We developed a noninvasive radiomics model based on CT imaging for the diagnosis of COVID-19 based on GGO lesions, which could be a promising supplementary tool for improving specificity for COVID-19 in a population confounded by ground glass opacity changes from other etiologies. | 2020-09-22 |
| 32959075 | We investigated the place of this new disease in the spectrum encompassing Kawasaki disease and myocarditis.Thirty two consecutive children referred to our centre for a suspicion of Kawasaki or a diagnosis of myocarditis were included and eventually divided into four groups: 11 Kawasaki diseases, 6 Kawasaki syndromes (children with another diagnosis), 7 myocarditis without Kawasaki clinical feature and 7 myocarditis with incomplete Kawasaki clinical features. | 2020-09-22 |
| 32959115 | Of the 33 patients imaged with Q-SPECT/CT, 6 patients (3 men, 3 women) had a laboratory confirmed diagnosis of COVID-19 (mean age, 55, ± 11.4 years, range 33-68). […] All patients had a current diagnosis of malignancy and had a moderate or high pre-test probability for PE (mean Wells score 2.8, range 2-4). | 2020-09-22 |
| 32959148 | Comorbidity prevalence among deceased individuals was similar in 2020 and 2015-2019: 71.1% of all deceased had a prior cardiovascular diagnosis, 30.0% of all deceased had a prior cardiac diagnosis. […] There were 493 deaths with COVID-19 in weeks 11-27, (59.8% male), and 75.1% had a prior cardiovascular diagnosis. | 2020-09-22 |
| 32959234 | Various diagnostic technologies have been under active development. […] The novel coronavirus disease (COVID-19) may induce pulmonary failures, and chest X-ray imaging becomes one of the major confirmed diagnostic technologies. | 2020-09-22 |
| 32959714 | Patient care often refers to the broad spectrum of care, prevention, and treatment that a provider delivers, while the point of a differential diagnosis is to make a distinction between 2 or more conditions that share similar signs or symptoms. […] The COVID-19 response has forced many of these basic medical values aside, like providing differential diagnosis or practicing bedside manner through social interaction, while physicians struggle to continue care for patients. […] As a result, newly formed hospital and clinical policies may have dangerously traded everyday diagnosis and treatment of patients for the pandemic and quarantine recommendations. | 2020-09-22 |
| 32959724 | The differential diagnosis of lung and pleural metastases and coronavirus disease 2019 (COVID-19) can be challenging. […] The final diagnosis was paraneoplastic fever. | 2020-09-22 |
| 32959730 | All patients meeting diagnosis criteria for ARDS according to the Berlin Definition, with PCR positive SARS-CoV2 infection and prolonged mechanical ventilation, defined as ≥2 days, treated at our ARDS referral center between March and April 2020 were included in a retrospective registry analysis. | 2020-09-22 |
| 32959978 | The very front line in defense against this pandemic is molecular diagnosis, which is an exceptional representation of how chemical translational biology can benefit our lives. | 2020-09-22 |
| 32960917 | We tested seven machine learning models and used a combination of those models for the final diagnostic classification. […] We found that our machine learning algorithm had excellent diagnostic metrics compared to SARS-CoV-2 PCR. | 2020-09-22 |
| 32960929 | Timely diagnosis of COVID-19 infected individuals and their prompt isolation are essential for controlling the transmission of SARS-CoV-2. […] In this context, a pooled sample testing strategy was evaluated in the setting of emerging disease outbreak in 3 central Indian districts to assess if the cost of the test and turn-around time could be reduced without compromising its diagnostic characteristics and thus lead to early containment of the outbreak. […] The diagnostic performance of qRT-PCR on pooled sample was compared with that of individual samples in a blinded manner. […] While pooling reduced the cost of diagnosis by 68% and the laboratory processing time by 66%, 5 of the 109 pools showed discordant results when compared with induvial samples. | 2020-09-22 |
| 32960938 | Many dental diagnosis and treatment procedures generate droplets and aerosols, and thus both dental staff and patients are at a high risk of becoming infected and transmitting COVID-19 to others. | 2020-09-22 |
| 32961061 | Except for the A_IgM and C_IgG systems, the optimal diagnostic thresholds and cutoff values of the other kits and their recommendations are inconsistent with each other. […] B_IgM had the worst AUC, and C_IgG had the best diagnostic accuracy. […] The D-Ab serum diagnosis kit is the most reliable detection system for anti-SARS-CoV-2 antibodies, which can be used as an alternative method for nucleic acid testing. | 2020-09-22 |
| 32961315 | The results show that the NWHL LDT multiplex assay performs as well as the modified CDC assay but is more efficient and cost-effective and can be used as a diagnostic assay and for epidemiologic surveillance and clinical management of SARS-CoV-2. | 2020-09-22 |
| 32961429 | Antibodies to SARS-CoV-2 serve as critical diagnostic markers for determining how broadly the COVID-19 pandemic has spread, confirming patient recovery, monitoring potential long-term effects of infection, and evaluating potential protection from reinfection. | 2020-09-22 |
| 32961451 | Low-dose computed tomography (LDCT) of the chest is a recommended diagnostic tool in early stage of COVID-19 pneumonia. | 2020-09-22 |
| 32962560 | This article aimed to evaluate the diagnostic accuracy of serologic methods for COVID-19 based on assay design and post-symptom-onset intervals. […] Two authors independently searched PubMed, Cochrane library, Ovid, EBSCO for case-control, longitudinal and cohort studies that determined the diagnostic accuracy of serology tests in comparison with NAATs in COVID-19 cases and used QUADAS-2 for quality assessment. […] Serology tests will play an important role in the clinical diagnosis for later stage COVID-19 patients. […] ELISA tests, detecting TAB or targeting combined N and S proteins had a higher diagnostic sensitivity compared to other methods. | 2020-09-23 |
| 32962703 | Analysis of cytokine levels at the point of diagnosis of SARS-CoV-2 infection can identify patients at risk of deterioration. | 2020-09-23 |
| 32962806 | To evaluate the diagnostic capacity of pulmonary angiography with multidetector computed tomography (MDCT) and iodine mapping in the diagnosis of pulmonary thromboembolism (PTE) in patients with Covid-19 disease. […] This makes it a highly useful tool for the accurate diagnosis and therapeutic orientation of patients with Covid-19 lung involvement. | 2020-09-23 |
| 32962848 | Few studies have described the nursing care provided to patients in isolation between suspicion of having the disease and a confirmed diagnosis. | 2020-09-23 |
| 32963028 | Increasing recognition of this diagnosis will thus lead to more appropriate and effective treatment strategies in COVID-19, which may lead to a further reduction of need for ventilatory support and improved survival. | 2020-09-23 |
| 32963170 | Elevated pancreatic enzymes levels and computed tomography findings led to the diagnosis of acute pancreatitis due to COVID-19. | 2020-09-23 |
| 32963215 | RESULTS A total of 158 cases were included according to COVID-19 diagnosis, and the treatment schemes were analyzed for identification of early indicators affecting COVID-19 progression. […] Analysis showed that patients’ age (χ²=10.640,=0.041); the time interval between onset and diagnosis (χ²=7.278, P=0.026); the source of cases (χ²=5.557, P=0.018); fever (χ²=5.676, P=0.014); dyspnea (χ²=113.085, P<0.001); muscle or joint pain (χ²=3.900, P=0.048); chest pain (χ²=13.446, P=0.006); the levels of lymphocytes (t=2.917, P=0.014), C-reactive protein (U=730.00, P<0.001), and aspartate aminotransferase (U=1235.00, P=0.002); damage in both lungs within 3 days of admission (χ²=7.632, P=0.003); and diabetes (χ²=6.675, P=0.010) were significantly correlated with the trend of intensification. […] CONCLUSIONS Older age, a long time interval from onset to diagnosis, imported cases from an affected area, dyspnea, muscle or joint pain, chest pain during the course of the disease, reduced lymphocytes, elevated C-reactive protein, computed tomography scan showing damage to both lungs within 3 days of admission, and diabetes mellitus are predictors for severe COVID-19. | 2020-09-23 |
| 32963216 | CONCLUSIONS The presented COVID-19 case, one of the first reported cases with evidence of right heart thrombus by transesophageal echocardiography, highlights the central role of diagnostic imaging strategies and the importance of adequate anticoagulation therapy in the management of severe COVID-19 cases in the ICU. | 2020-09-23 |
| 32963413 | A series of six novel imidazole anchored azo-imidazole derivatives (L1-L6) have been prepared by the simple condensation reaction of azo-coupled ortho-vaniline precursor with amino functionalised imidazole derivative and the synthesized derivatives (L1-L6) have been characterized by different analytical and spectroscopic techniques. | 2020-09-23 |
| 32963440 | The added advantage of ultrasonography is that it is a fantastic diagnostic tool that is easily available at the bedside, repeatable, more objective, and has a steep learning curve. […] Vital Role of Ultrasound in the Era of COVID-19: Arriving at the Right Diagnosis Real Time. | 2020-09-23 |
| 32963672 | There are 160 candidate vaccines under clinical trials across the world using different molecular targets and techniques. | 2020-09-23 |
| 32963819 | While diagnostic and therapeutic efforts have been focused on respiratory complications of the disease, several ocular implications have also emerged. […] The aim of this review was to summarize ophthalmological implications of SARS-CoV-2 infection to serve as a reference for eye care and other physicians for prompt diagnosis and management. | 2020-09-23 |
| 32963823 | All consecutive inpatients with laboratory and/or CT COVID-19 diagnosis were included in this study. | 2020-09-23 |
| 32963907 | The presumptive diagnosis of Hamman-Rich syndrome was made based on a combination of factors after ruling out other similar clinical entities, especially in the setting of an ongoing COVID-19 pandemic. | 2020-09-23 |
| 32964061 | Diagnostic performance was assessed and extrapolated for site combinations. […] Nasopharyngeal specimens, followed by throat specimens, offer the highest clinical sensitivity for COVID-19 diagnosis in early illness. | 2020-09-23 |
| 32964068 | These results have helped shape diagnostic stewardship guidelines, in particular guidance to decrease repeated testing in the inpatient setting to optimize test utilization and preserve resources. | 2020-09-23 |
| 32964177 | Health workers must consider them as suspicion indices for empirical diagnosis of severe acute respiratory syndrome coronavirus 2 infection. | 2020-09-23 |
| 32964211 | Access to rapid diagnosis is key to the control and management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] We describe our diagnostic accuracy assessment of a novel, rapid point-of-care real time RT-PCR CovidNudge test, which requires no laboratory handling or sample pre-processing. | 2020-09-23 |
| 32964657 | A total of 81 polymerase chain reaction (PCR)-confirmed COVID-19 positive subjects, of whom 54 self-reported smell loss, were prospectively recruited ≤5 days from diagnosis date between May 8, 2020, and July 8, 2020. | 2020-09-23 |
| 32965007 | In particular, 11 diagnoses of pulmonary embolism and 1 diagnosis of deep vein thrombosis were formulated. […] These patients require a high index of clinical suspicion and an accurate diagnostic approach, in order to immediately start an appropriate anticoagulant treatment. | 2020-09-23 |
| 32965008 | The present case report aims to make a discussion concerning oral manifestations in a patient with a confirmed diagnosis of COVID-19. […] She also showed lesions in the median lower lip semimucosa and severe pruritus, with a clinical course of 14 days, in which we performed a clinical diagnosis of herpes simplex infection. | 2020-09-23 |
| 32965014 | The 3 SARS-CoV-2 infected patients were clinically diagnosed as COVID-19 because they meet the diagnostic criteria listed in “Chinese Clinical Guidance for COVID-19 Pneumonia diagnosis and treatment”, including epidemic history, symptom and pathogenic detection, as well as abnormalities of the laboratory and radiological data. […] Detection of the pathogen is the unique means for definite COVID-19 diagnosis. | 2020-09-23 |
| 32965018 | In this study, the early diagnosis of this disease through artificial intelligence (AI) technology is explored. […] Although this study does not provide a final solution, it highlights the most promising lines of research on AI technology for the diagnosis of COVID-19. […] The major contribution of this work is a discussion on the following substantial issues of AI technology for preventing the severe effects of COVID-19: (1) rapid diagnosis and detection, (2) outbreak and prediction of virus spread, and (3) potential treatments. | 2020-09-23 |
| 32965269 | ; The quality of the diagnostic and treatment process is characterized by many quantitative indicators. […] The greatest number of defects in the organization and technology of medical care is noted in two blocks: the quality of medical records and diagnostic measures. | 2020-09-23 |
| 32965310 | To investigate the diagnostic accuracy of a chest X-ray (CXR) score and of clinical and laboratory data in predicting the clinical course of patients with SARS coronavirus 2 (SARS-CoV-2) infection. | 2020-09-23 |
| 32965332 | Thus, we emphasise the importance of differential diagnosis in COVID-19 suspected cases. | 2020-09-23 |
| 32965351 | Faced with this scenario, Epidemiology plays an important role, given that its techniques and methods have contributed to generating knowledge, assisting in decision making in healthcare. | 2020-09-23 |
| 32965356 | In addition, the limitations of the myocarditis diagnosis were discussed since only fulminant myocarditis cases have been mentioned in the current literature. […] There are a lot of difficulties in the differential diagnosis of acute myocarditis in the context of COVID-19. | 2020-09-23 |
| 32965358 | Laboratory is not specific enough in the pre-diagnosis. | 2020-09-23 |
| 32965363 | The aim of this study is to analyze the prognostic significance of ABO and Rh blood group antigens along with various parameters in patients followed-up with the diagnosis of COVID-19. | 2020-09-23 |
| 32965369 | The aim of this rapid systematic review is to analyze the prevalence of clinical, socioeconomic, and demographic characteristics, laboratory and imaging findings, diagnostic tests, and treatment information of older adults with COVID-19. […] Patients aged 60 years or older with a confirmed diagnosis of SARS-CoV-2 infection will be included. | 2020-09-23 |
| 32965455 | This is a series of 14 cases with a laboratory-confirmed diagnosis of COVID-19. | 2020-09-23 |
| 32965457 | The areas of research interest were also identified in the funding documents; the most common topic was “diagnosis” and the least common was “equipment for treatment.” | 2020-09-23 |
| 32965521 | The focus on SARS-CoV‑2 and the uncharacteristic symptoms of these two diseases make it much more difficult to find the correct diagnosis. | 2020-09-23 |
| 32965559 | Our findings demonstrate the utility of telemedicine tools to avoid the potential negative impact of interruption or postponement of diagnostic and/or therapeutic procedures. | 2020-09-23 |
| 32965677 | A nucleocapsid protein (NP)-based enzyme-linked immunosorbent assay (ELISA) detection method is not only important in disease diagnosis, but is required for the evaluation of vaccine efficacy during the development of an inactivated SARS-CoV-2 vaccine. | 2020-09-23 |
| 32966064 | Rapid point-of-care viral antigen detection methods have been previously employed for the diagnosis of respiratory viruses such as influenza and respiratory syncytial viruses. […] Therefore, the direct detection of SARS-CoV-2 viral antigens in patient samples could also be used for diagnosis of active infection, and alternative methodologies for specific and sensitive viral protein detection should be explored. […] Targeted mass spectrometry techniques have enabled the identification and quantitation of a defined subset of proteins/peptides at single amino acid resolution with attomole level sensitivity and high reproducibility. […] Potentially, mass spectrometry-based methods for viral antigen detection may deliver higher throughput and could serve as a complementary diagnostic tool to RT-PCR. | 2020-09-23 |
| 32966283 | The concurrent circulation of dengue and coronavirus disease 2019 (COVID-19) may produce many unfavourable outcomes-such as co-infections; delays in diagnosis, treatment, and mitigation measures; overwhelming of the healthcare system; underreporting of cases; deterioration in surveillance and control interventions; and exacerbation of social inequalities. | 2020-09-23 |
| 32966645 | Thus, development and integration in clinics of fast and sensitive diagnostic tools are essential. | 2020-09-23 |
| 32966744 | The predominant diagnostic screens in use for SARS-CoV-2 detection are molecular techniques such as nucleic acid amplification tests. […] In this Review, we compare current and emerging isothermal diagnostic methods for COVID-19. […] We outline the molecular and serological techniques currently being used to detect SARS-CoV-2 infection, past or present, in patients. […] We also discuss ongoing research on isothermal techniques, CRISPR-mediated detection assays, and point-of-care diagnostics that have potential for use in SARS-CoV-2 detection. | 2020-09-23 |
| 32966822 | Compared with patients undergoing surgery within 2 months of diagnosis, we found worse OS for patients with a surgical delay of 3-4 months (hazard ratio [HR] 1.12, 95% confidence interval [CI] 1.00-1.25) or 5-6 months (HR 1.51, 95% CI 1.19-1.91). | 2020-09-23 |
| 32966857 | Effective, sensitive, and reliable diagnostic reagents are of paramount importance for combating the ongoing coronavirus disease 2019 (COVID-19) pandemic when there is neither a preventive vaccine nor a specific drug available for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] It will cause a large number of false-positive and false-negative tests if currently used diagnostic reagents are undermined. […] Based on genotyping of 31,421 SARS-CoV-2 genome samples collected up to July 23, 2020, we reveal that essentially all of the current COVID-19 diagnostic targets have undergone mutations. […] We show that due to human immune response induced APOBEC mRNA (C > T) editing, diagnostic targets should also be selected to avoid cytidines. […] Our findings might enable optimally selecting the conservative SARS-CoV-2 genes and proteins for the design and development of COVID-19 diagnostic reagents, prophylactic vaccines, and therapeutic medicines. | 2020-09-23 |
| 32967312 | The Department of Diagnostic Imaging (DDI) conceived an organizational approach based on three different pathways for low-risk, high-risk, and confirmed Coronavirus Disease 19 (COVID-19) patients to accomplish three main targets: guarantee a safe pathway for non-COVID-19 patients, ensure health personnel safety, and maintain an efficient workload. […] Patient screening and dedicated diagnostic pathways allowed the maintenance of high standards of care while working in safety. | 2020-09-24 |
| 32967427 | Hence, a specific and rapid assay is crucial for the early diagnosis and active monitoring of individuals potentially exposed to SARS-CoV-2 for controlling the COVID-19 outbreak. […] Therefore, we conclude that the developed LFSM assay can be used alone or complementary to the RT-PCR or other methods for the diagnosis and monitoring of the patients to curb community transmission and the pandemic. | 2020-09-24 |
| 32967466 | The scientific community has put in much effort and published studies that described COVID-19’s biology, transmission, clinical diagnosis, candidate therapeutics, and vaccines. | 2020-09-24 |
| 32967887 | Marked departures from linear effects of covariates were identified by employing smoothing splines within a generalised additive modelling framework. 3 secondary and tertiary level centres in Greater Manchester, the UK. 392 hospitalised patients with a diagnosis of COVID-19. 392 patients with a COVID-19 diagnosis were identified. | 2020-09-24 |
| 32968075 | Methodological simplification could increase diagnostic availability and efficiency, benefitting patient care and infection control. […] Our data, including benchmarking using 597 clinical patient samples and a standardised diagnostic system, demonstrate that direct RT-PCR is viable option to extraction-based tests. | 2020-09-24 |
| 32968304 | Specimen quality, and proper transportation is vital for accurate diagnosis. | 2020-09-24 |
| 32968306 | The diagnosis of these pathological conditions can be challenging during COVID-19; furthermore, their prevalence and prognostic significance have not been elucidated yet. […] The purpose of this review is to take stock of the various aspects of non-ischemic ventricular dysfunction that may occur during COVID-19 and of the diagnostic implications related to the use of cardiac imaging techniques. | 2020-09-24 |
| 32968416 | From January to March 2020, COVID-19 patients were divided into two groups according to the Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (trial version 7), with mild and ordinary cases as Group-1 and critical and severe cases as Group-2. […] In Group-1, there were two cases of normal chest CT scan results, one case of fibrosis, and 25 cases of abnormalities during the first diagnosis, mainly manifested as single or scattered ground-glass shadows. | 2020-09-24 |
| 32968429 | A diagnosis of cancer does not appear to increase the risk of death or a severe outcome in COVID-19 patients with cancer compared with those without cancer. | 2020-09-24 |
| 32968435 | A plethora of published studies have investigated the role of imaging such as chest X-rays and computer tomography in coronavirus disease 2019 (COVID-19) automated diagnosis. […] The presented study highlights the importance of a robust preprocessing protocol for image analysis within a heterogeneous imaging dataset and assesses the potential diagnostic value of the presented COVID-19 model by comparing its performance to the state of the art. | 2020-09-24 |
| 32968677 | Adequate knowledge was found among health care providers regarding diagnostic tests, modes of transmission, incubation period and preventive strategies. | 2020-09-24 |
| 32968883 | To conduct a multireader validation study to evaluate the interobserver variability and the diagnostic accuracy for the lung involvement by COVID-19 of COVID-19 Reporting and Data System (CO-RADS) score. […] Receiver operating characteristic (ROC) curves were computed to investigate diagnostic yield. […] CO-RADS showed high diagnostic accuracy and moderate interrater agreement across readers with different levels of expertise. […] • COVID-19 Reporting and Data System (CO-RADS) demonstrated a good diagnostic accuracy for lung involvement by COVID-19 with an average AUC of 0.72 (95% CI 67-75%). | 2020-09-24 |
| 32969188 | In this scenario, we highlight the use of radiofrequency and neuromodulation therapies, techniques that do not interfere with the immune response. | 2020-09-24 |
| 32969711 | All these data demonstrate the relevance of renal function assessment in patients with COVID-19 and the need of early kidney-directed diagnostic and therapeutic approaches. | 2020-09-24 |
| 32969761 | Area under the receiver operating characteristic curve (AUC), sensitivity, and specificity were calculated to characterize diagnostic performance. | 2020-09-24 |
| 32969769 | The seroconversion dynamic was assessed by symptom onset and day of RT-PCR diagnosis. […] Conclusions: The NG-test is a bedside serological assay that could serve as a complementary source of diagnostic information to RT-PCR and chest imaging. | 2020-09-24 |
| 32969949 | Diagnostic performance was compared with radiologists’ performance and was assessed by area under the receiver operating characteristics (AUC). | 2020-09-24 |
| 32969974 | To discuss the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection by nucleic acid and antibody testing as well as its contribution to mitigating the spread of coronavirus disease 2019. […] Nucleic acid testing (NAT) is the firstly developed and most widely used diagnostic technique for SARS-CoV-2 infection. […] The diagnostic sensitivity can be significantly improved by combination of RNA and antibody testing. […] Viral RNA testing combining with serological testing could improve the early diagnosis of SARS-CoV-2 infection, which has great value for clinical practice and public health. | 2020-09-24 |
| 32970246 | This was a multicentered cohort study identifying patient characteristics and diagnostic markers present on initial evaluation associated with mortality in hospitalized COVID-19 patients. | 2020-09-24 |
| 32970329 | Mutation coldspots may present as conserved diagnostic and therapeutic targets were found in ORF7b, ORF9b, and ORF14. […] These findings suggest that the virion’s genotype and phenotype in a specific population should be considered in developing diagnostic tools and treatment options. | 2020-09-24 |
| 32970352 | The objective of this review is to provide a comparative view among current diagnostic methods, focusing on recently suggested biosensors for the detection of SARS-CoV2 in clinical samples. | 2020-09-24 |
| 32970384 | Majority of fine-needle aspiration done in these cases, during the lockdown period, were either in cases for recurrence or primary diagnosis. | 2020-09-24 |
| 32970512 | On the basis of our review and personal experience, we have outlined opportunities for telehealth to play a role in every step of the cancer care journey from diagnosis to therapy to surveillance to clinical trials for medical, surgical, and radiation oncology. | 2020-09-24 |
| 32970556 | The purpose of this study was to assess the diagnostic and prognostic value of chest radiographs (CXR) for coronavirus disease 2019 (COVID-19) at presentation. […] The score use for diagnosis and prognosis of COVID-19 was evaluated with the area under the receiver operating characteristic curve. […] However, the score was inversely correlated with a COVID-19 diagnosis within ≤2 days, and a positive correlation was found six days after symptom onset.Interobserver agreement with regard to separating normal from abnormal CXRs was moderate (k = 0.408) with low specificity (25% and 27%). […] Definite pleural effusion had almost perfect agreement (k = 0.833) and substantially reduced the odds of a COVID-19 diagnosis. […] Chest radiography was found not to be a valid diagnostic tool for COVID-19, as normal or near-normal CXRs are more likely early in the disease course. […] Pleural effusions at presentation suggest a diagnosis other than COVID-19. | 2020-09-24 |
| 32970559 | Participants were expected to meet a minimum passing score (MPS) of 100%, determined by an expert panel using the Mastery Angoff and Patient Safety standard-setting techniques. […] Testing occurred before and after an in-person demonstration of proper donning and doffing techniques and 20 minutes of deliberate practice. | 2020-09-24 |
| 32970560 | The unprecedented COVID-19 pandemic has resulted in rapidly evolving best practices for transmission reduction, diagnosis, and treatment. | 2020-09-24 |
| 32970595 | This article provides a comprehensive review of the technological advances of US-E research on lung disease diagnosis. […] We introduce the basic principles and major techniques of US-E and provide information on various applications in lung disease assessment. […] Finally, the potential applications of US-E to the diagnosis of COVID-19 pneumonia is discussed. | 2020-09-24 |
| 32970772 | An association was observed between HDL-C and LDL-C concentrations on the day of the first VAP diagnosis and mortality ([HDL-C] = 0.6[0.5-0.9] mmol/L in survivors vs. | 2020-09-24 |
| 32970774 | By screening a patient information system for International Statistical Classification of Diseases and Related Health Problems (ICD) diagnosis codes covering more than 85% of acute hospital admissions in the state of Styria (~1.24 million inhabitants), we retrospectively identified patients with admission diagnoses for MI (I21, I22), PE (I26), and AAD (I71). | 2020-09-24 |
| 32970782 | There is a clear requirement for an accurate SARS-CoV-2 antibody test, both as a complement to existing diagnostic capabilities and for determining community seroprevalence. […] We therefore evaluated the performance of a variety of antibody testing technologies and their potential use as diagnostic tools. […] However, the head-to-head comparison of multiple sero-diagnostic assays on identical sample sets revealed that performance is highly dependent on the time of sampling, with sensitivities of over 95% seen in several tests when assessing samples from more than 20 days post onset of symptoms. | 2020-09-24 |
| 32970840 | The objective of this study was to examine the skin of hospitalized patients with a confirmed diagnosis of COVID-19 disease and describe the real prevalence of skin manifestations. […] A cross-sectional study, which included hospitalized patients in Cruces University Hospital from April 14-30, 2020, with a laboratory-confirmed diagnosis of COVID-19 (with polymerase chain reaction and/or serology tests), was conducted. | 2020-09-24 |
| 32970921 | Patients with ibuprofen prescription claims between January 1, 2020, and before COVID-19 diagnosis or April 30, 2020 (last available prescription) were compared with patients without ibuprofen prescription claims. […] Outcome was a 30-day composite of severe COVID-19 diagnosis with acute respiratory syndrome, intensive care unit admission, or death. | 2020-09-24 |
| 32971239 | The median time from illness onset to diagnosis was 4.0 days (range 0-39 days) Severe patients diagnosed after 14 days of symptoms onset had higher viral load than patients with mild disease. | 2020-09-24 |
| 32971326 | To report real-world diagnostic performance of chest x-ray (CXR) readings during the COVID-19 pandemic. […] Radiologists were grouped by CXR reading experience (Group-1, >10 years; Group-2, <10 years), diagnostic performance indexes were calculated for each radiologist and for the two groups. […] Real-world CXR diagnostic performance during the COVID-19 pandemic showed overall high sensitivity with higher specificity for more experienced radiologists. | 2020-09-24 |
| 32971906 | During this dramatic situation, the normal scientific protocols for the development of new diagnostic procedures or drugs are frequently not completely applied in order to speed up these processes. | 2020-09-25 |
| 32972235 | Although a recent report indicated favorable responses to the interleukin-1 receptor antagonist, anakinra in eight patients with COVID-19 secondary HLH diagnosed using the HScore calculation, others have suggested that the diagnosis of secondary HLH is uncommon and that the use of the HScore has limited value in guiding immunomodulatory therapy for COVID-19. […] We hypothesize that identification of HLH may relate to the severity or timing of cytokine release and suggest distinguishing between cytokine release syndrome and secondary HLH, reserving the latter term for cases fulfilling diagnostic criteria. | 2020-09-25 |
| 32972761 | We report on a 49-year-old black female kidney transplant recipient who presented 25 years after transplant with clinical features of nephrotic syndrome following a diagnosis of COVID-19. | 2020-09-25 |
| 32972763 | In this review, we report a case of a bone’s metastatic breast cancer in Malian patient treated by chemotherapy in whom SRAS-COV-2’s diagnosis was made 9days after the onset gastrointestinal symptoms. | 2020-09-25 |
| 32972979 | Suspicious symptoms were reported for one player; an immediate additional PCR test as well as all subsequent diagnostic and antibody tests proved negative for coronavirus. | 2020-09-25 |
| 32973066 | To monitor the spreading of COVID-19 in Italy from February 24th to March 13th (the date of the Italian lockdown), official daily data for PM10 levels were collected from all Italian provinces between February 9th and February 29th, taking into account the maximum lag period (14 days) between the infection and diagnosis. | 2020-09-25 |
| 32973656 | Data were analyzed via bag of word and sentiment analysis techniques in R. | 2020-09-25 |
| 32973730 | It has played a key role in the rapid diagnosis of viruses in patient samples and has contributed significantly to the clarification of virus structure and function, helping to guide the public health response to emerging viral infections. | 2020-09-25 |
| 32973919 | At present, diagnosis and treatment are of great concern. | 2020-09-25 |
| 32973965 | Major advancements in the hyperacute diagnosis and treatment of stroke have justified our call-to-action slogan of “Time is Brain”-faster therapy leads to superior outcomes. | 2020-09-25 |
| 32974109 | A random forest (RF) algorithm was used to predict the prognoses of COVID-19 patients and identify the optimal diagnostic predictors for patients’ clinical prognoses. | 2020-09-25 |
| 32974210 | Seven patients (39%) were symptomatic for COVID-19 at the time of diagnosis and symptoms began 2 (±2) days before. […] Six patients (33%) were on active anti-tumor treatment: 2 (33%) received anti-tumor therapy within 2 weeks before the infection diagnosis and 2 (33%) continued oncological treatment after SARS-CoV-2 positivity. […] Eight (44%) patients died within a mean of 12 days (±8) from the infection diagnosis. | 2020-09-25 |
| 32974267 | Aimed at identifying viral RNA in the various compartments of the organism of sick subjects, diagnostic tests are carried out. | 2020-09-25 |
| 32974268 | Related scientific papers have rapidly extended information regarding the diagnosis, treatment and epidemiology of COVID-19 infection. | 2020-09-25 |
| 32974417 | Teleconsultation may be used to advise patients for therapy and symptom control measures, as well as to advise new patients regarding diagnostic tests. | 2020-09-25 |
| 32974418 | There were modifications in diagnostic pathways, interventions, and follow-ups across all organ sites. | 2020-09-25 |
| 32975110 | We are living such a scenario on a global scale with the pandemic crisis of COVID-19 where expectations for virological and serological diagnosis tests have been and are still gigantic. | 2020-09-25 |
| 32975205 | Results Mean gestational age at diagnosis was 30.6±9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. […] At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; p<0.001), birthweight (OR: 1.17, 95% CI 1.09-1.12.7 per 100 g decrease; p=0.012) and maternal ventilatory support, including either need for oxygen or CPAP (OR: 4.12, 95% CI 2.3-7.9; p=0.001) were independently associated with composite adverse fetal outcome. | 2020-09-25 |
| 32976318 | The BLUS findings were statistically compared with formal radiology reports of computed tomographies as the criterion standard for the diagnosis of Covid-19 pneumonia. | 2020-09-25 |
| 32976519 | We use machine learning techniques to analyze about 1.9 million Tweets (written in English) related to coronavirus collected from January 23 to March 7, 2020. | 2020-09-25 |
| 32976847 | Based on the current evidence ophthalmologists should consider measures that include social distancing, wearing masks, sterilisation techniques and managing clinic volumes. | 2020-09-25 |
| 32977050 | Sociodemographic data, clinical characteristics, referred symptoms, diagnosis and information on patients’ illness course following the emergency consultations were collected. […] Subjects who were living in psychiatric residential treatment facilities, had cannabis addiction and a diagnosis of obsessive-compulsive disorder were significantly more likely to present to emergency psychiatric consultations during lockdown. | 2020-09-25 |
| 32977063 | Overall 74.5% (n = 38) of patients with xerostomia, 78.8% (n = 52) of patients with gustatory dysfunctions and 71.1% (n = 33) of patients with olfactory dysfunctions reported that all symptoms appeared before COVID-19 diagnosis. | 2020-09-25 |
| 32977074 | There were 1,145 respondents (response rate: 20%). 1,019 had a diagnosis of MS and responded completely (average age: 54.2 years, range: 20-81; 79% female; 64% relapsing remitting, 22% secondary progressive, 12% primary progressive; 88% in the USA). 748 (73%) used a DMT in the last year, primarily higher-efficacy therapies: ocrelizumab (n=238), dimethyl fumarate (n=85), fingolimod (n=80). | 2020-09-25 |
| 32977128 | Early diagnosis and treatment of VTE is warranted. | 2020-09-25 |
| 32977349 | To compare the diagnostic efficacy between two different real-time reverse transcription polymerase chain reaction (RT-PCR) test kits for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid detection and provide references for laboratories. | 2020-09-25 |
| 32977359 | Cardiac complications are common and associated with mortality in critically ill patients with COVID-19; however, the diagnostic and prognostic implications of critical care echocardiography (CCE) have not been studied. | 2020-09-25 |
| 32977781 | The majority of participants considered the platform of virtual reality training realistic for the initial clinical assessment (77%), diagnostic activity (94%), and treatment options (81%). | 2020-09-26 |
| 32978065 | COVID-19 diagnosis was clinically confirmed by positive reverse transcription polymerase chain reaction test or, if negative, by other methods. | 2020-09-26 |
| 32978173 | We defined cancer survivors as those with a self-reported diagnosis of cancer (n=854,7.6%). | 2020-09-26 |
| 32978237 | To achieve an early diagnosis, we analysed the laboratory results of the first 7 days of hospitalisation. | 2020-09-26 |
| 32978251 | The primary objective was in-hospital mortality within 30 days of COVID-19 diagnosis among patients with solid cancer versus patients without cancer. | 2020-09-26 |
| 32978307 | We independently externally validated the performance candidate prognostic models, identified through a living systematic review, among consecutive adults admitted to hospital with a final diagnosis of COVID-19. | 2020-09-26 |
| 32978309 | Asthma and asthma severity (step suggested by GINA) was defined using the diagnostic code and history of asthma medication usage. | 2020-09-26 |
| 32978337 | In the absence of a proper and effective antibody test, the diagnosis is presently based on a reverse-transcription PCR of nasopharyngeal and oropharyngeal swab samples. | 2020-09-26 |
| 32978339 | The COVID-19 pandemic has had variable impacts in the WHO South-East Asia Region to date, but in the countries most affected there has been targeted diversion and repurposing of tuberculosis services, health-care workers and diagnostic equipment. […] The combined effects of COVID-19, containment measures and fragmentation of tuberculosis services have resulted in delays in diagnosis or non-diagnosis and disruption in treatment resulting in increased morbidity, mortality, transmission and drug resistance. | 2020-09-26 |
| 32978346 | The coronavirus disease 2019 (COVID-19) pandemic has put a great burden on countries as a result of the demand for laboratory diagnostic testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Through a questionnaire-based survey carried out between 23 March and 2 April, we estimated the daily tests that could be done by the 44 facilities, excluding the national referral laboratory, first assigned to be COVID-19 diagnostic laboratories. […] Even assuming this potential could be tapped, several provinces would still be poorly served by diagnostic services in the event of a surge in cases. | 2020-09-26 |
| 32978363 | BACKGROUND The aim of this study was to assess the diagnostic utility of iron homeostasis determinations for prediction of severity of COVID-19. | 2020-09-26 |
| 32978532 | Aim This systematic review sought to assess and scrutinise the validity and practicality of published and preprint reports of prediction models for the diagnosis of coronavirus disease 2019 (COVID-19) in patients with suspected infection, for prognosis of patients with COVID-19, and for identifying individuals in the general population at increased risk of infection with COVID-19 or being hospitalised with the illness.Data sources A systematic, online search was conducted in PubMed and Embase. […] All these steps were done according to the aspects of the transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD) and preferred reporting items for systematic reviews and meta-analyses (PRISMA). […] The most common predictors of diagnosis and prognosis of COVID-19 were age, body temperature, lymphocyte count and lung imaging characteristics. […] Influenza-like symptoms and neutrophil count were regularly predictive in diagnostic models, while comorbidities, sex, C-reactive protein and creatinine were common prognostic items. […] C-indices (a measure of discrimination for models) ranged from 0.73 to 0.81 in prediction models for the general population, from 0.65 to more than 0.99 in diagnostic models, and from 0.68 to 0.99 in the prognostic models. | 2020-09-26 |
| 32978920 | Chest physiotherapy techniques applied were deep breathing, ACBT, paced breathing and diaphragmatic breathing. […] This study shows that it is safe and feasible to provide early physiotherapy treatment techniques in patients with COVID-19 using appropriate measures of infection prevention and cross contamination. | 2020-09-26 |
| 32978927 | The covid cases need an early diagnosis with treat and care model. | 2020-09-26 |
| 32979013 | The first negative nasopharyngeal (NP) swab was documented one month after initial diagnosis, when SARS-CoV-2 antibodies were also detected. | 2020-09-26 |
| 32979101 | In arthritis patients, no significant differences in RS14 were observed after stratification for specific diagnosis, age, or disease duration and activity. | 2020-09-26 |
| 32979256 | To efficiently monitor the COVID-19 pandemic for surveillance purposes, reliable serological rapid diagnostic tests (RDTs) are desirable for settings where well-established high-throughput bench-top solutions are not available. […] The test results remain difficult to interpret and therefore the RDT can currently not be recommended for routine diagnostic or surveillance use. | 2020-09-26 |
| 32979305 | We extracted the weekly number of clinical codes entered into patient records overall, and for six high-level categories: symptoms and observations, diagnoses, prescriptions, operations and procedures, laboratory tests, and other diagnostic procedures. […] A rebound in future workload could be imminent as COVID-19 restrictions ease and patients with undiagnosed conditions or delayed diagnosis present to primary and secondary health-care services. […] Such services should prioritise the diagnosis and treatment of these patients to mitigate potential indirect harms to protect public health. | 2020-09-26 |
| 32979322 | The authors present these models as techniques that can be used at any stage in an unpredictable pandemic timeline. | 2020-09-26 |
| 32979369 | The aim of this study was to investigate 28-day mortality after COVID-19 diagnosis in the European kidney replacement therapy population. […] Additional data on all patients with a diagnosis of COVID-19 were collected from seven European countries encompassing 4298 patients. | 2020-09-26 |
| 32979425 | Two hundred and twenty-four consecutive patients with confirmed diagnosis of SARS-CoV-2 infection and definite outcomes (discharge or death) were retrospectively analyzed. | 2020-09-26 |
| 32979475 | The CDC protocol for SARS-CoV2 RT-PCR diagnosis (2019-nCoV CDC kit) is considered a gold standard worldwide; based on three different FAM probes (N1 and N2 for viral detection; RP for RNA extraction quality control), three reactions per sample are needed for SARS-CoV-2 diagnosis. […] For a typical 96-well plate, this pool assay allows 96 samples processing, speeding up diagnosis and reducing cost while maintaining clinical performance, particularly useful for SARS-CoV-2 diagnosis at developing countries. | 2020-09-26 |
| 32979575 | Test capacity should be increased to enable more effective diagnostic tests. | 2020-09-26 |
| 32979911 | Effective control of this infectious disease requires access to diagnostic techniques, for both case finding and epidemic size estimation. | 2020-09-27 |
| 32980137 | We present our experience with the use of a diagnostic score, developed for rHLH, in a kidney transplant recipient hospitalized with COVID-19. […] The calculated H-Score for our patient fell below the diagnostic cut-off value for rHLH. | 2020-09-27 |
| 32980489 | Asymptomatic subjects cleared the virus earlier than symptomatic (22 vs 34,2 days, p<0.0001); the presence of fever at the time of diagnosis was associated with a longer time to viral clearance (RR 11.45, 95% CI 8.66-14.25, p<0.0001). | 2020-09-27 |
| 32980614 | The aims of the study were to review the rapidly emerging COVID-19 literature to determine 1) the relationship between obstructive sleep apnoea (OSA) and adverse COVID-19 outcomes and, 2) potential causal mechanisms 3) what effect COVID-19 has had on OSA diagnosis and 4) what effect COVID-19 has had on treatment and management of OSA during this period. […] It is clear that the pandemic has had a major effect on the treatment management and diagnosis of OSA and moving forward it may be necessary to explore new diagnosis and treatment pathways for these individuals. | 2020-09-27 |
| 32980807 | The COVID-19 pandemic in the United States created a unique situation where multiple molecular SARS-CoV-2 diagnostic assays rapidly received Emergency Use Authorization by the FDA and were validated by laboratories and utilized clinically, all within a period of a few weeks. | 2020-09-27 |
| 32980852 | CONCLUSIONS The results of diagnostic tests for Covid-19 should be re-evaluated whenever there are clinical mismatches or doubts, as false-positive Covid-19 test results can occur. | 2020-09-27 |
| 32980900 | Based on the characteristics that shelter hospital only treats patients with mild illness, tests of shelter laboratory, including coronavirus nucleic acid detection, IgM/IgG antibody serology detection, monitoring and auxiliary diagnosis and/or a required blood routine, urine routine, C-reactive protein, calcitonin original, biochemical indicators (liver enzymes, myocardial enzymes, renal function, etc.) and blood coagulation function test etc, were used to provide important basis for the diagnosis and treatment of the disease. | 2020-09-27 |
| 32981005 | Computed tomography (CT) has been employed as a diagnostic tool in the evaluation of patients with clinical suspicion of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) infection with a reported sensitivity of higher than reverse transcription polymerase chain reaction (RT-PCR) test. […] In addition, CT findings of such diseases may resemble manifestations of COVID-19 (such as ground glass opacities with or without superimposed consolidation), making the diagnosis of viral infections, more challenging on imaging. […] Otherwise, the diagnosis of COVID-19 in such patients must be cautiously made according to the clinical context and laboratory results, considering a very high clinical index of suspicion on imaging. | 2020-09-27 |
| 32981112 | Compared to other in-situ techniques, transmission electron microscopy is the only method to visualize assembled virions in tissues and will be required to prove SARS-CoV-2 replication outside the respiratory tract. | 2020-09-27 |
| 32981180 | The prostate cancer diagnostic pathway accounts for over 50,000 prostate biopsies each year. | 2020-09-27 |
| 32981664 | Among long-term care residents diagnosed with COVID-19, nearly one-half were asymptomatic at the time of diagnosis. | 2020-09-28 |
| 32981694 | On univariate analysis, hospital location in Queens or Brooklyn, age ≤65 years, treatment for a new cancer diagnosis versus recurrence and COVID-19 positivity were associated with treatment modifications. | 2020-09-28 |
| 32982038 | This research employs text mining techniques and dynamic network analysis to investigate the actors’ risk and crisis communication on Twitter regarding message types, communication sufficiency, timeliness, congruence, consistency and coordination. | 2020-09-28 |
| 32982575 | GIS-based techniques include the spatial and temporal distribution of pollutants using interpolation method, and on the other hand, statistical methods like analysis of variance (ANOVA) was applied to determine the mean differences two phases and correlation matrix helps to understand the changing association of the pollutants in pre- and during lockdown phases. | 2020-09-28 |
| 32982600 | This review summarizes the current coronavirus disease 2019 (COVID-19) transmission pathways, high-risk factors, diagnostic points, pathogenesis, and therapeutic drugs to provide the prevention and treatment theories for COVID-19. […] The basis for clinical diagnosis of COVID-19 is not just the detection of viral nucleic acids as the gold standard. […] The diagnostic accuracy improves when viral nucleic acid test is combined with clinical symptoms, CT results, and biochemical tests. | 2020-09-28 |
| 32982849 | Specifically, a telematic workshop was implemented to teach emotional literacy and relaxation techniques combined with the practice of the techniques in an autonomous manner. […] The results show that Jacobson’s progressive relaxation techniques, Schultz’s autogenic training, abdominal relaxations, and visualizations are effective in lowering the anxiety levels of university students as an alternative to pharmacotherapy. | 2020-09-28 |
| 32983056 | Testing for the presence of co-pathogens going forward will assist in the diagnosis and optimal treatment of suspected SARS-CoV-2 respiratory infections in the current pandemic. | 2020-09-28 |
| 32983097 | Restricted by 40 and 14 HLA-class I and II allotypes, respectively, these responses have wide population coverage and might be of considerable academic, diagnostic and therapeutic interest. | 2020-09-28 |
| 32983373 | The shortage of N95 respirators may be overcome by extended use and reuse - comprising rotation and decontamination by approved techniques. | 2020-09-28 |
| 32983409 | Right heart catheterization is an essential diagnostic modality in the evaluation of pulmonary hypertension. | 2020-09-28 |
| 32983419 | To combat this pandemic, effective screening techniques for infected patients are indispensable. […] There is no doubt that the use of chest X-ray images for radiological assessment is one of the essential screening techniques. | 2020-09-28 |
| 32983689 | While the definitive diagnosis of the coronavirus disease 19 (COVID-19) is mainly made by the polymerase chain reaction (PCR), some PCR-negative cases are diagnosed typically by a computed tomography (CT) scan’s radiology. […] However, when the laboratory values and the radiological findings were combined with the patient’s history, COVID-19 was excluded and the chronic eosinophilic pneumonia was accepted as a diagnosis. | 2020-09-28 |
| 32983694 | There was a statistically significant decrease in final diagnosis of TIA at our hospital, all California hospitals, and all West Regional hospitals during the March-April 2020 window, suggesting that some patients with minor stroke symptoms may not be presenting to the hospital in the midst of the pandemic. | 2020-09-28 |
| 32983724 | Higher monitoring of patients with DM and COVID-19 is advised, as well as rapid and accurate diagnostic tests and treatment. | 2020-09-28 |
| 32983909 | Machine Learning and Image Analysis research has been making great progress in many directions in the healthcare field for providing support to subsequent medical diagnosis. […] In this paper, we have propose three research directions with methodologies in the fight against the pandemic namely: Chest X-Ray (CXR) images classification using deep convolution neural networks with transfer learning to assist diagnosis; Patient Risk prediction of pandemic based on risk factors such as patient characteristics, comorbidities, initial symptoms, vital signs for prognosis of disease; and forecasting of disease spread & case fatality rate using deep neural networks. | 2020-09-28 |
| 32984017 | Our case highlights the diagnostic pitfalls in diagnosing COVID-19 in B-cell depleted patients and discuss the role of B-cell depletion in the course and treatment of COVID-19. […] In conclusion, our case report can help physicians to avoid diagnostic pitfalls for COVID-19 in hemato-oncological patients under chemoimmunotherapy and tries to explain the role of B-cell depletion and SARS-CoV-2 specific T cells in this context. | 2020-09-28 |
| 32984363 | Between March 9 and April 28, 32 asymptomatic patients and caregivers were tested and 68 rT-PCR diagnostic assays have been performed with two positive results. | 2020-09-28 |
| 32984388 | CTPA was performed on 76 inpatients, and a diagnosis of PE was made in 32 (2.6% [95%CI 1.7-3.5%]). | 2020-09-28 |
| 32984405 | However, transthoracic echocardiography is a fast and reliable bedside method to establish the diagnosis of cardiac complications, including acute coronary syndromes, pericarditis, myocarditis, and pulmonary embolism. | 2020-09-28 |
| 32984566 | The negative selection identified in SARS-CoV-2 protein coding genes may help the identification of highly conserved regions useful to implement new future diagnostic protocols. | 2020-09-28 |
| 32984615 | Only few cases showed positive results for IgM, suggesting that at least 2 of these kits used in this study were unsuitable for diagnosis of COVID-19. | 2020-09-28 |
| 32984642 | The diagnosis of coronavirus disease 2019 using biomarkers and indicators at point-of-care level is much crucial. […] Finally, we have outlined pros and cons of diagnostic approaches and future directions. | 2020-09-28 |
| 32984664 | The results presented here can help designing country-specific diagnostic strategies and prioritizing the mutations for functional interpretation and experimental validations. | 2020-09-28 |
| 32984764 | No bleeding manifestations were reported in 31% cases at diagnosis. | 2020-09-28 |
| 32984768 | Currently, the diagnosis and treatment of SARS-CoV-2 infection in patients with chronic kidney disease (CKD) are still unclear. | 2020-09-28 |
| 32984797 | In this prediction model development and validation study, we applied machine learning techniques to clinical data from a large cohort of patients with COVID-19 treated at the Mount Sinai Health System in New York City, NY, USA, to predict mortality. […] We analysed patient-level data captured in the Mount Sinai Data Warehouse database for individuals with a confirmed diagnosis of COVID-19 who had a health system encounter between March 9 and April 6, 2020. | 2020-09-28 |
| 32984799 | Although a left ventricular thrombus is a rare COVID-19 complication, performing appropriate diagnostic tests could improve COVID-19 mortality in patients with dilated cardiomyopathy. | 2020-09-28 |
| 32984847 | This retrospective cohort study included de-identified information of all veterans in the US Veterans Health Administration clinical administrative database aged 18 years or older with rheumatoid arthritis, systemic lupus erythematosus, or associated rheumatological conditions (based on International Classification of Diseases, 10th edition, diagnostic codes) who were alive on March 1, 2020. | 2020-09-28 |
| 32984859 | Six categories of diagnosis were distinguished: 1) contusions, 2) no physeal fractures, 3) physeal fractures (Salter-Harris), 4) sprains/subluxations,5) dislocations, 6) others (tendinitis, wounds, low back pain, joint inflammation). | 2020-09-28 |
| 32984911 | Due to the rapid spread of this novel coronavirus and its related disease, COVID-19, a reliable, simple, fast, and low-cost detection method is necessary for patient diagnosis and tracking worldwide. […] The laboratory detection techniques include RT-PCR, RT-LAMP, electrochemical and optical biosensors for RNA detection, and whole virus or viral proteins detection assays. | 2020-09-28 |
| 32985200 | The diagnosis currently relies on a multiplex of criteria including the epidemiology, clinical manifestations and in vitro diagnostics. […] But, considering the sensitivity and specificity based shortcomings and the lacunae in monitoring the spread of the virus, there is an immense need to develop integrated smart devices based on novel, safe, rapid and accurate diagnostic techniques and implement them on a large scale to curb this outbreak in the country and the world as a whole. […] Keywords: clinical manifestations; COVID-19; diagnosis; PCR; SARS-COV-2; serology. | 2020-09-28 |
| 32985848 | In this report, we describe a patient with a new manifestation of cardiac involvement in the setting of a COVID-19 diagnosis: that of takotsubo cardiomyopathy. | 2020-09-28 |
| 32986289 | This will aid early diagnostic assessment in patients with high index of suspicion and subsequent management in the acute phase. | 2020-09-28 |
| 32986528 | This finding suggests that a diagnosis of active cancer alone and recent anticancer therapy do not predict worse COVID-19 outcomes and therefore, recommendations to limit cancer-directed therapy must be considered carefully in relation to cancer-specific outcomes and death. | 2020-09-28 |
| 32986664 | Antibodies being valuable for diagnostic therapeutic and protective purposes are suitable to be addressed in this context. | 2020-09-28 |
| 32986671 | All SARS-CoV-2 RT-PCR diagnostic tests performed before on-site visits were negative and only three IgG serological tests were positive. | 2020-09-28 |
| 32986819 | We explored outcomes related to severe COVID-19 in HCWs and the diagnostic performance of symptoms to detect SARS-CoV-2 infection in HCWs. | 2020-09-28 |
| 32986881 | Early cardiac magnetic resonance was crucial for the diagnosis of postpartum cardiomyopathy and for the exclusion of virus-related myocarditis, allowing us to decide on a prudent and supportive clinical approach. | 2020-09-28 |
| 32986907 | We performed a cross-sectional analysis of patients admitted under code-stroke protocol to our center with a final diagnosis of ischemic brain infarction. | 2020-09-28 |
| 32987722 | Furthermore, our data suggest that rapid RT-PCR can be implemented for sensitive and specific molecular diagnosis of COVID-19 in locations where sophisticated laboratory instruments are not available. | 2020-09-29 |
| 32987902 | Diagnosis of venous thromboembolism was made in 21 cases (28.4%) and thrombotic events were associated with positive pressure ventilation support (p = 0.024) and hospitalization in ICU (p < 0.0001). | 2020-09-29 |
| 32987950 | Mass spectrometry-based methods using swab and gargle samples have been reported with promise, but have not approached the task from a systematic analysis of the entire diagnostic process. […] These features reveal the diagnostic utility of MALDI-ToF mass spectrometry as a powerful and economically attractive global solution. | 2020-09-29 |
| 32988427 | The United Nations warned of COVID-19-related mental health crisis; however, it is unknown whether there is an increase in the prevalence of mental disorders as existing studies lack a reliable baseline analysis or they did not use a diagnostic measure. | 2020-09-29 |
| 32988429 | In this paper, we intend to add information that may help by using epidemic simulation techniques with stochastic individual contact models and several extensions. | 2020-09-29 |
| 32988730 | An 83-year-old man with hypertension and smoking history and a 62-year-old man with a drinking habit were transferred to our hospital with a diagnosis of COVID-19. | 2020-09-29 |
| 32989379 | Automatic diagnosis of COVID-19 from medical imaging enables precise medication, helps to control community outbreak, and reinforces coronavirus testing methods in place. | 2020-09-29 |
| 32989410 | We present advances in modeling techniques that have led to fundamental disease discoveries and impacted clinical translation. | 2020-09-29 |
| 32989413 | Several molecular diagnostic techniques have been developed for accurate and precise diagnosis of COVID-19. […] Novel genomic techniques have helped in the understanding of the disease pathology, origin, and spread of COVID-19. […] Several rapid, accurate, and sensitive diagnostic methods have been developed; those are based on the principle of detecting SARS-CoV-2 nucleic acids in clinical samples. | 2020-09-29 |
| 32989419 | Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies has become an important tool, complementing nucleic acid tests (NATs) for diagnosis and for determining the prevalence of coronavirus disease 2019 (COVID-19) in population serosurveys. […] Serological testing should be incorporated into diagnostic algorithms for SARS-CoV-2 infection to identify additional cases where NAT was not performed and resolve cases where false-negative and false-positive NATs are suspected. | 2020-09-29 |
| 32989425 | With an ambispective cohort design, eligible patients are those discharged, deceased or alive, from any hospital center with a confirmed diagnosis or a COVID-19 high suspicion. | 2020-09-29 |
| 32989430 | Only 5·2% of breast cancer diagnosis occurred after quarantine in Hubei compared with 15·3% in other provinces (OR= 0·30, 95%CI 0·24-0·38). postoperative endocrine therapy were least affected compared with different regions after quarantine (OR=0·37 [95%CI 0·19-0·73]). […] Compared with intervals from diagnosis to treatment before quarantine restrictions, the average time increased with significance from 3·5 to 7·7 days in Hubei and 5·7 to 7·7 days in other provinces (p< 0·001). […] After implementation of COVID-19 quarantine restrictions, fewer diagnosis and surgery with significant delays were seen when compared with treatment before. | 2020-09-29 |
| 32989587 | This is a new challenge for diagnosis and rehabilitation, with important consequences for the involved neuropsychological services. | 2020-09-29 |
| 32989642 | Further, we demonstrate that 30 min of thermal inactivation at 56°C could inactivate viable viruses from clinical COVID-19 specimens without attenuating the qRT-PCR diagnostic sensitivity. […] Use of this method would reduce the potential for secondary infections in BSL2 conditions during diagnostic procedures. […] Importantly, infectious virus can be inactivated in clinical specimens without compromising the sensitivity of the diagnostic RT-PCR assay. | 2020-09-29 |
| 32989673 | We evaluated the risk for COVID-19 diagnosis, hospitalization, and respiratory failure associated with OSA by univariate tests and logistic regression, adjusting for diabetes, hypertension, and BMI to account for potential confounding in the association between OSA, COVID-19 hospitalization, and progression to respiratory failure. | 2020-09-29 |
| 32989997 | In the mini review we investigate the use of NLR as a surrogate marker for diagnosis and stratification of COVID-19. | 2020-09-29 |
| 32989998 | This article offers few insights on scattered issues; including the clinical characteristics, pathology and diagnosis, as well as treatment perspectives and public health approach. | 2020-09-29 |
| 32989999 | The remote diagnosis (mail, phone or video-call) and treatment methods that can be expected in the near future may be even closer with the Corona virus (Tab. | 2020-09-29 |
| 32990100 | COVID-19 is identified via X-ray or computed tomography scans and further corroborated with molecular diagnostics techniques, including polymerase chain reaction. […] Herein, we depict an extensive update on the clinical aspects of COVID-19, including strategies for the regulation of the transmission, diagnosis, treatment, and pathogenesis of SARS-CoV-2 infections. | 2020-09-29 |
| 32990149 | According to the diagnosis and treatment plan, the included cases were classified into mild, moderate, severe, and critical. | 2020-09-29 |
| 32990479 | This review provides an overview of the underlying immune profile of COVID-19-related CRS as well as laboratory markers for acute diagnosis and chronic follow-up of patients with SARS-CoV-2 and CRS. […] Detection of SARS-CoV-2 RNA is the gold standard method for diagnosis of COVID-19 in the context of CRS but assay performance varies and is susceptible to false-negative results even as patients clinically deteriorate due to decreased viral shedding in the setting of CRS. | 2020-09-29 |
| 32991573 | The diagnosis was confirmed by RT-PCR testing using the CFX96 Real-Time System (Bio-Rad, USA) from nasopharyngeal swabs. | 2020-09-29 |
| 32991730 | By partnering with international groups such as Biophorum and Bio Supply Chain Management Alliance, the wish stimulate discussion about how sociotechnical thinking about HFE may help develop better monitoring and investigative techniques to strengthen global supply chains. | 2020-09-29 |
| 32991900 | All the above-mentioned strategies, as well as the role of nanomedicine for the diagnosis and treatment of SARS-CoV-2 infection, have been discussed in this review. | 2020-09-29 |
| 32992136 | This study aims to develop and test a new computer-aided diagnosis (CAD) scheme of chest X-ray images to detect coronavirus (COVID-19) infected pneumonia. | 2020-09-29 |
| 32992351 | The study aimed to compare the quantitative blood loss (QBL) and hemorrhage-related outcomes of pregnant women with and without a coronavirus disease 2019 (COVID-19) diagnosis. […] This retrospective cohort study of all live deliveries at Boston Medical Center between April 1, 2020 and July 22, 2020 compares the outcomes of pregnant women with a laboratory-confirmed COVID-19 positive diagnosis and pregnant women without COVID-19. […] Women with a COVID-19 diagnosis at their time of delivery were significantly more likely to identify as a race other than white (p = 0.01), to deliver preterm (p = 0.05), to be diagnosed with preeclampsia with severe features (p < 0.01), and to require general anesthesia (p < 0.01). […] COVID-19 positive pregnant patients had no increased adjusted odds of obstetric hemorrhage (adjusted odds ratio [aOR]: 0.41, 95% confidence interval [CI]: 0.17-1.04) and no increased adjusted odds of the maternal morbidity composite (aOR: 0.98, 95% CI: 0.50-1.93) when compared with those without a diagnosis of COVID-19. […] Pregnant women with COVID-19 diagnosis do not have increased risk for obstetric hemorrhage, increased QBL or risk of maternal morbidity compared with pregnant women without a COVID-19 diagnosis. […] Further research is needed to describe the impact of a COVID-19 diagnosis on maternal hematologic physiology and pregnancy outcomes. […] · COVID-19 diagnosis is not associated with increase in obstetric hemorrhage.. […] · COVID-19 diagnosis is not associated with increase in blood loss.. | 2020-09-29 |
| 32992435 | HRCT is the best radiological approach for the diagnosis and differential diagnosis of COVID-19, and to assess the presence of ILD. | 2020-09-29 |
| 32992436 | Objective: To investigate the application of severity classification according to the protocol on the Diagnosis and Treatment of coronavirus disease 2019(COVID-19)by the National Health Commission of China, pneumonia severity index(PSI) and CURB-65 in risk stratification and prognostic assessment of COVID-19. […] Patients were divided into 3 groups (common, severe, and critical type) at admission according to the sixth version of the protocol issued by the National Health Commission of China on Diagnosis and Treatment of COVID-19. | 2020-09-29 |
| 32992511 | Furthermore, an association between COVID-19 infection and venous thromboembolism has been reported in several series around the world.For this reason, methods used to improve diagnostic tools, pharmacological thromboprophylaxis and type of anticoagulants are discussed in this expert opinion. | 2020-09-30 |
| 32992752 | We present a case of fulminant NPPE in a patient during general anesthesia which illustrates the eye-catching CT findings that can occur in NPPE and eventually support diagnosis. […] With regard to the current pandemic, we include a discussion of the typical imaging patterns of COVID-19 as a radiological differential diagnosis of NPPE. | 2020-09-30 |
| 32993524 | However, with the adoption of different diagnosis criteria, the variation of new cases could impose various influences in the predictive model. | 2020-09-30 |
| 32993652 | In this study, we propose to generate a more accurate diagnosis model of COVID-19 based on patient symptoms and routine test results by applying machine learning to reanalyzing COVID-19 data from 151 published studies. […] We demonstrated that computational methods trained on large clinical datasets could yield ever more accurate COVID-19 diagnostic models to mitigate the impact of lack of testing. | 2020-09-30 |
| 32993833 | When trends over a four-year period were examined, there was a significantly higher lethality of attempt (p<0.001), and significant differences in diagnosis (p=0.031) in 2020 in comparison with the three previous years. | 2020-09-30 |
| 32994047 | Between March 11, when the first case was detected, until July 23, Cuba reported 2,449 cases of COVID-19 that included 28 (1.14%) with a diagnosis of cancer. | 2020-09-30 |
| 32994052 | The pathology of this event is complex and multifactorial, but the main problem now is the timely diagnosis of these phenomena, which can reduce the mortality and morbidity of patients. […] Imaging techniques, especially computed tomography pulmonary angiography, can well solve this puzzle and lead to timely treatment of these patients. | 2020-09-30 |
| 32994259 | We incorporated serial measurements that harbour aetiological, diagnostic and predictive information. […] Our study design is expected to enhance aetiological, diagnostic and prognostic understanding of the disease. | 2020-09-30 |
| 32994260 | All patients receiving inpatient hospital care >18 years who receive a diagnosis of COVID-19 are eligible for inclusion. | 2020-09-30 |
| 32994364 | A machine learning model trained on VirScan data predicted SARS-CoV-2 exposure history with 99% sensitivity and 98% specificity; a rapid Luminex-based diagnostic was developed from the most discriminatory SARS-CoV-2 peptides. | 2020-09-30 |
| 32994647 | These new gene editing techniques include one which has garnered a great deal of attention, the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems, as well as other, less well-known ones. | 2020-09-30 |
| 32994704 | It also discusses the causes, transmission, symptoms, diagnosis, treatments and prevention measures to identify an applicable measure to control COVID-19. | 2020-09-30 |
| 32994918 | The diagnostic uncertainty for children with abdominal pain has increased during the COVID-19 pandemic with the additional consideration of both COVID-19 and paediatric inflammatory multisystem syndrome-temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (PIMS-TS) alongside appendicitis, mesenteric adenitis and other less common causes of abdominal pain. | 2020-09-30 |
| 32995758 | Comprehensive understanding of the serological response to SARS-CoV-2 infection is important for both pathophysiologic insight and diagnostic development. […] This proof-of-concept study demonstrates that ReScan will have broad applicability for other emerging infectious diseases or autoimmune diseases that lack a valid biomarker, enabling a seamless pipeline from antigen discovery to diagnostic using one recombinant protein source. | 2020-09-30 |
| 32995855 | We performed data collection concerning the coronavirus disease 2019 (COVID-19) pandemic-related delay in the diagnosis of cancers to individuate proper corrective procedures. […] The diagnostic decrease in colorectal (-46.6%), prostate (-45%), and bladder (-43.6%) cancer was the most relevant among internal malignancies; for prostate, however, high-grade tumors were only moderately affected (-21.7%). […] Diagnosis of cutaneous malignancies was mostly affected by the lockdown; among internal malignancies, corrective actions were mostly needed for colorectal cancer and invasive bladder cancer. | 2020-09-30 |
| 32996368 | Results were synthesized and reported under 4 themes. (a) The need of AI during this pandemic: AI can assist to increase the speed and accuracy of identification of cases and through data mining to deal with the health crisis efficiently, (b) Utility of AI in COVID-19 screening, contact tracing, and diagnosis: Efficacy for virus detection can a be increased by deploying the smart city data network using terminal tracking system along-with prediction of future outbreaks, (c) Use of AI in COVID-19 patient monitoring and drug development: A Deep learning system provides valuable information regarding protein structures associated with COVID-19 which could be utilized for vaccine formulation, and (d) AI beyond COVID-19 and opportunities for Low-Middle Income Countries (LMIC): There is a lack of financial, material, and human resources in LMIC, AI can minimize the workload on human labor and help in analyzing vast medical data, potentiating predictive and preventive healthcare. […] AI-based tools can be a game-changer for diagnosis, treatment, and management of COVID-19 patients with the potential to reshape the future of healthcare in LMIC. | 2020-09-30 |
| 32996452 | Only 8.5% (943/11,086) of suspected COVID-19 cases were concurrently tested for dengue serology due to a compatible overlapping clinical syndrome, and dengue was established as an alternative diagnosis in 2% (207/10,218) of suspected COVID-19 cases that tested negative. […] In a dengue epidemic season coinciding with a COVID-19 pandemic, dengue was established as an alternative diagnosis in a minority of COVID-19 suspects, likely due to early availability of basic diagnostics. | 2020-09-30 |
| 32996607 | This cross-sectional observational study evaluated 45 health professionals who were initially seen in screening tents and had a diagnosis of coronavirus disease 2019 as confirmed by a reverse transcription polymerase chain reaction and lung involvement diagnosed by LUS. | 2020-09-30 |
| 32996705 | Essential HIV case-finding services for pregnant and breastfeeding women and children should be maintained and include maternal testing, diagnostic testing for infants exposed to HIV, index testing for children whose biological parents or siblings are living with HIV, as well as for children/adolescents presenting with symptoms concerning for HIV and comorbidities. | 2020-09-30 |
| 32997361 | The diagnosis of infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents major challenges. […] Chest imaging tests are being used in the diagnosis of COVID-19 disease, or when RT-PCR testing is unavailable. […] To determine the diagnostic accuracy of chest imaging (computed tomography (CT), X-ray and ultrasound) in people with suspected or confirmed COVID-19. […] Two studies evaluated the diagnostic accuracy of point-of-care ultrasound and both reported zero false negatives (with 10 and 22 participants having undergone ultrasound, respectively). […] Our findings indicate that chest CT is sensitive but not specific for the diagnosis of COVID-19 in suspected patients, meaning that CT may not be capable of differentiating SARS-CoV-2 infection from other causes of respiratory illness. […] Because of limited data, accuracy estimates of chest X-ray and ultrasound of the lungs for the diagnosis of COVID-19 should be carefully interpreted. […] Future diagnostic accuracy studies should avoid cases-only studies and pre-define positive imaging findings. […] Planned updates of this review will aim to: increase precision around the accuracy estimates for CT (ideally with low risk of bias studies); obtain further data to inform accuracy of chest X rays and ultrasound; and continue to search for studies that fulfil secondary objectives to inform the utility of imaging along different diagnostic pathways. | 2020-09-30 |
| 32997560 | Information obtained from computed tomography (CT) and radiological images is important for clinical diagnosis. | 2020-09-30 |
| 32997704 | Inclusion criteria were: a) age over 18 years; b) confirmed diagnosis of COVID-19 infection (with nasopharyngeal/oropharyngeal swab); c) invasive mechanical ventilation and d) clinical indication for tracheostomy. | 2020-09-30 |
| 32997739 | Total IgA, IgG and aPL were measured with clinical diagnostic kits. | 2020-09-30 |
| 32997808 | In this review, we discuss recent publications on asthma and review the studies that have reported on the different aspects of the prevalence, risk factors and prevention, mechanisms, diagnosis, and treatment of asthma. […] A reliable diagnosis of asthma, disease endotyping, and monitoring its severity are of great importance in the management of asthma. | 2020-09-30 |
| 32997812 | In a mixed-design evaluation study, we compared the diagnostic accuracy of serological immunoassays that are based on various SARS-CoV-2 proteins and assessed the neutralizing activity of antibodies in patient sera. […] ELISAs targeting RBD and S1 protein of SARS-CoV-2 are promising immunoassays which shall be further evaluated in studies verifying diagnostic accuracy and protective immunity against SARS-CoV-2. | 2020-09-30 |
| 32998066 | As effective point-of-care diagnosis tools, simple, low-cost and rapid sensors have the potential to greatly accelerate the screening and diagnosis of suspected patients to improve their treatment and care. […] In this communication, we discuss the feasibility of an integrated point-of-care biosensor system with mobile health for wastewater-based epidemiology (iBMW) for early warning of COVID-19, screening and diagnosis of potential infectors, and improving health care and public health. | 2020-09-30 |
| 32998213 | With recent advancements in robotics, innovative diagnostic and treatment devices have been developed and several translational attempts made. […] Although the existing endoscopic devices have thus far provided substantial improvements in the effectiveness of diagnosis and treatment, there are certain aspects that represent unwavering predicaments of the current gastroenterology practice. […] The combination of robotics and artificial intelligence, as well as remote telehealth endoscopy services, are also discussed, as viable solutions to improve existing platforms for diagnosis and treatment are emerging. | 2020-10-01 |
| 32998438 | The availability of this in-house ELISA protocol would be valuable for various diagnostic and epidemiological applications. | 2020-10-01 |
| 32998840 | Multiple polymerase chain reaction (RT-PCR) is considered the gold standard diagnostic investigation for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19). | 2020-10-01 |
| 32999467 | Together, the proposed SARS-CoV-2 T cell epitopes enable identification of heterologous and post-infectious T cell immunity and facilitate development of diagnostic, preventive and therapeutic measures for COVID-19. | 2020-10-01 |
| 32999782 | Methods A retrospective review of all emergency department (ED) patients that presented to an American College of Surgeons (ACS) verified rural level one trauma center with associated diagnostic coding for assault was conducted during the Coronavirus 2019 (COVID-19) lockdown, integral dates March 16, 2020 to April 30, 2020. | 2020-10-01 |
| 32999916 | Convergence of data across the clinical interview, reliable and brief remote cognitive tests, and remote neurological exam increase confidence in clinical interpretation and diagnosis. | 2020-10-01 |
| 33000108 | A definitive diagnosis of COVID-19 is made after a positive result is obtained on reverse transcription-polymerase chain reaction assay. […] Since CXR has limited sensitivity and specificity in COVID-19, it is not suitable as a first-line diagnostic tool. | 2020-10-01 |
| 33000462 | The paper by Colmenero et al. presents a study of skin biopsies from paediatric patients presenting with chilblains during the COVID-19 pandemic.1 Seven cases were examined by histopathological and immunohistochemical techniques, and one of these was additionally studied by transmission electron microscopy. | 2020-10-01 |
| 33000560 | The systematic review was evaluated by Case Series Studies and the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies (PRISMA). | 2020-10-01 |
| 33000640 | The spread of the SARS-CoV-2 infection among population has imposed a re-organization of healthcare services, aiming at stratifying patients and dedicating specific areas where patients with suspected COVID-related respiratory disease could receive the necessary health care assistance while waiting for the confirmation of the diagnosis of COVID-19 disease. | 2020-10-01 |
| 33001323 | In response to the pressing need to flexibly deliver high-quality care to individuals with psychosis, this brief report proposes high yield cognitive behavioral techniques for psychosis (HY-CBt-p) facilitated by task sharing and digital enhancements. […] HY-CBt-p is delivered over fewer sessions than formulation-based Cognitive Behavioral Therapy for psychosis (CBTp), can be learned by a range of providers, and includes techniques such as developing a normalizing explanation; techniques to reduce anxiety, depression, and insomnia, which perpetuate psychotic symptoms; self-monitoring; reality testing; and wellness planning. | 2020-10-01 |
| 33001407 | All patients filled a questionnaire concerning working and household settings, recent flu symptoms or COVID-19 diagnosis, and family loss due to COVID-19 infection. | 2020-10-01 |
| 33001409 | Associations between baseline characteristics and clinical stages at diagnosis (uncomplicated vs. complicated) were assessed using logistic regression models. […] The primary COVID-19 diagnosis was made in 35.0% (755/2,155) during complicated clinical stages. […] A significant univariate association between age; sex; body mass index; smoking; diabetes; cardiovascular, pulmonary, neurological, and kidney diseases; ACE inhibitor therapy; statin intake and an increased risk for complicated clinical stages of COVID-19 at diagnosis was found. […] Multivariable analysis revealed that advanced age [46-65 years: adjusted odds ratio (aOR): 1.73, 95% CI 1.25-2.42, p = 0.001; 66-85 years: aOR 1.93, 95% CI 1.36-2.74, p < 0.001; > 85 years: aOR 2.38, 95% CI 1.49-3.81, p < 0.001 vs. individuals aged 26-45 years], male sex (aOR 1.23, 95% CI 1.01-1.50, p = 0.040), cardiovascular disease (aOR 1.37, 95% CI 1.09-1.72, p = 0.007), and diabetes (aOR 1.33, 95% CI 1.04-1.69, p = 0.023) were associated with complicated stages of COVID-19 at diagnosis. […] The LEOSS cohort identified age, cardiovascular disease, diabetes and male sex as risk factors for complicated disease stages at SARS-CoV-2 diagnosis, thus confirming previous data. | 2020-10-01 |
| 33001626 | We hope to shed light on developing better solutions for faster and better vaccine development strategies through the use of biomaterials, biomolecular engineering, nanotechnology, and microfabrication techniques. | 2020-10-01 |
| 33001783 | Imaging plays an essential role in the diagnosis of all manifestations of the disease, as well as its related complications, and proper utilization and interpretation of imaging examinations is crucial. […] With the growing global COVID-19 outbreak, a comprehensive understanding of the diagnostic imaging hallmarks, imaging features, multisystemic involvement, and evolution of imaging findings is essential for effective patient management and treatment. | 2020-10-01 |
| 33001828 | The aim of this study is to evaluate and compare the diagnostic accuracies of web-based COVID-19 symptom checkers. | 2020-10-01 |
| 33001830 | They enable a rapid and detailed assessment of tissue and organ involvement in disease processes that are relevant to diagnosis and management, particularly in the context of the COVID-19 pandemic. […] Taken together with nucleic acid testing, we found that CT scans can allow for the rapid diagnosis of COVID-19. | 2020-10-01 |
| 33002409 | Sepsis is a life-threatening clinical condition demanding accurate and rapid diagnosis of the culprit pathogen, thereby to improve prognosis. […] Pathogen determination through blood culture is the gold standard for diagnosis but has limitations due to low sensitivity. […] Recently, circulating DNAs derived from pathogenic organisms were found in the plasma of patients with sepsis and were further proved to be more sensitive biomarkers for the diagnosis of the pathogen origin in sepsis. […] Our findings have improved our understanding of microbial circulating DNA in patients with sepsis as a potential methodology for the accurate diagnosis of sepsis, especially in light of an urgent need for such a diagnosis associated with the COVID-19 infection. | 2020-10-01 |
| 33002475 | The antibody response to SARS-CoV-2 is not well understood yet, but the availability of sensitive and specific serological assays will be crucial for the early diagnosis of infection, for epidemiological studies and for defining the presence of neutralizing antibodies in response to a possible vaccine. | 2020-10-01 |
| 33002560 | Diagnosis and screening of frailty, a condition characterized by an increased vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool which is strongly recommended by healthcare providers concerned with hospitalized elderly population. | 2020-10-01 |
| 33002725 | Acute disseminated encephalomyelitis (ADEM) is an uncommon diagnosis in adults. | 2020-10-01 |
| 33002740 | Patients with COVID-19 who had confirmed diagnosis with SARS-CoV-2 nucleic acid RT-PCR were enrolled into the study. | 2020-10-01 |
| 33002929 | The most promising techniques utilize heat, hydrogen peroxide, microwave generated steam, or ultraviolet light. | 2020-10-01 |
| 33003024 | This was based on patient disease severity defined by the presence of alert symptoms, symptom severity for dysphagia and abdominal pain, and diagnostic investigation findings. […] The order of priority of procedures was established on the basis of a 4-tiered system factoring both presence and severity of symptoms or prior diagnostic testing results. | 2020-10-01 |
| 33003102 | However, progressive neck pain and swelling, coupled with the eventual growth of Fusobacterium necrophorum on blood culture, eventually led to the correct diagnosis of Lemierre syndrome. | 2020-10-01 |
| 33003439 | In this study, the eating habits of 170 countries were evaluated in order to find correlations between these habits and mortality rates caused by COVID-19 using machine learning techniques that group the countries together according to the different distribution of fat, energy, and protein across 23 different types of food, as well as the amount ingested in kilograms. | 2020-10-02 |
| 33003634 | The time interval from symptom onset to diagnosis in HCWs and non-HCWs dropped rapidly over time. | 2020-10-02 |
| 33004102 | Strengthening health systems and maintaining essential service delivery during health emergencies response is critical for early detection and diagnosis, prompt treatment, and effective control of pandemics, including the novel coronavirus disease (COVID-19). | 2020-10-02 |
| 33004166 | Based on up-to-date research and psychological diagnostic manuals of Diagnostic and Statistical Manual of Mental Disorders, 5th edition and International Classification of Diseases, 11th revision, we describe associated psychological disorders and experiences that may arise related to COVID-19. | 2020-10-02 |
| 33004274 | Quantitative estimates for the global impact of COVID-19 on the diagnosis and management of patients with inborn errors of metabolism (IEM) are lacking. | 2020-10-02 |
| 33004276 | Diagnostic radiographers in Gauteng providing chest CT, chest radiograph and MRI services are frontline workers experiencing these unprecedented times. […] Therefore, this study undertook to explore diagnostic radiographers’ experiences of COVID-19. […] A qualitative approach using an asynchronous opened-ended online questionnaire was used to explore diagnostic radiographers’ experiences of COVID-19. […] Responses from purposively sampled diagnostic radiographers in Gauteng SA, underwent thematic analysis. […] Sixty diagnostic radiographers representing both the private and public health sector responded to the questionnaire. […] Besides experiencing a shift in their professional work routine and home/family dynamics, diagnostic radiographers’ well-being has also been impacted by COVID-19. […] Understanding the impact of COVID-19 on diagnostic radiographers will allow radiology departments’ management, hospital management, professional bodies and educational institutions to re-evaluate provision of resources, training, employee wellness programs as well as policies and procedures. | 2020-10-02 |
| 33004426 | We undertook a rapid systematic review with the aim of identifying evidence that could be used to answer the following research questions: (1) What is the clinical effectiveness of tests that detect the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inform COVID-19 diagnosis? […] (2) What is the clinical effectiveness of tests that detect the presence of antibodies to the SARS-CoV-2 virus to inform COVID-19 diagnosis? […] Systematic review and meta-analysis of studies of diagnostic test accuracy. […] Measures of diagnostic accuracy (sensitivity, specificity, positive/negative predictive value) were the main outcomes of interest. […] For antibody tests, 10 studies reported diagnostic accuracy outcomes: sensitivity ranged from 18.4% to 96.1% and specificity 88.9% to 100%. […] However, the lack of a true reference standard for SARS-CoV-2 diagnosis makes it challenging to assess the true diagnostic accuracy of these tests. […] Evidence is rapidly emerging on the effectiveness of tests for COVID-19 diagnosis and management, but important uncertainties about their effectiveness and most appropriate application remain. […] Estimates of diagnostic accuracy should be interpreted bearing in mind the absence of a definitive reference standard to diagnose or rule out COVID-19 infection. | 2020-10-02 |
| 33004602 | We assessed CSF SARS-CoV-2 RNA along with CSF biomarkers of intrathecal inflammation (CSF white blood cell count, neopterin, β2-microglobulin (β2M) and immunoglobulin G-index), blood-brain-barrier (BBB) integrity (albumin ratio), and axonal injury (CSF neurofilament light chain protein [NfL]) in 6 patients with moderate to severe COVID-19 and neurologic symptoms who had undergone a diagnostic lumbar puncture. | 2020-10-02 |
| 33004773 | As regard pediatric COVID-19 cases, more than 4000 cases (have been reported; however, these figures are likely to be underestimated since they are influenced by the number of diagnostic tests carried out. | 2020-10-02 |
| 33005213 | In the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reverse transcriptase-PCR (RT-PCR) technique is often used. […] We have observed high correlation between different PCR kits, however, using different PCR kits during the pandemic may provide a more accurate diagnosis of SARS-CoV-2, since despite correlation there are a number of patients showing contradicting diagnosis. | 2020-10-02 |
| 33005417 | Asymptomatic patients may transmit SARS-CoV-2, highlighting the importance of early diagnosis and treatment. | 2020-10-02 |
| 33005486 | Although real-time RT-PCR methods targeting specific gene(s) have widely been used to diagnose the COVID-19 patients, however, recently developed more convenient, cheap, rapid, and specific diagnostic tools targeting antigens or CRISPR-Cas-mediated method or a newly developed plug and play method should be available for the resource-poor developing countries. […] This review updates current knowledge on origin, genomic evolution, development of the diagnostic tools, and the preventive or therapeutic remedies of the COVID-19. | 2020-10-02 |
| 33005541 | As COVID-19 patients are commonly having clotting disorders, endothelial and organ dysfunction, coagulopathy, and liable for pulmonary thromboembolism (PTE), it is important to select those COVID-19 patients who are at higher risk of PTE, and practice CT pulmonary angiography (CTPA) for the diagnosis of PTE, especially in case of significant increase of D-dimer values. | 2020-10-02 |
| 33005550 | This diagnosis had implications for the treatment of her cancer, and a number of important decisions had to be made. | 2020-10-02 |
| 33006070 | The immunosuppressed status of some cancer patients increases their risk of infection compared with the general population, and cancer treatment within 2 weeks of COVID-19 diagnosis was reported as a risk factor for developing severe events. | 2020-10-02 |
| 33006508 | Since 1995, ASET has periodically published updates to recommendations for best practices in infection prevention for Neurodiagnostic technologists. […] All Neurodiagnostic technologists who have direct patient care are responsible for ensuring the use of best practices to prevent the spread of infection. | 2020-10-02 |
| 33006571 | These advances in telemedicine range from individual to population levels, allowing the exchange of patient information for diagnosis and management of health problems, primary care prevention, and education of physicians via distance learning. | 2020-10-02 |
| 33006832 | Diagnostic tests for the severe acute respiratory syndrome coronavirus 2 were the resource the EDs missed most: 55% reported that tests were scarce often or very often. […] Large hospital EDs less often reported that diagnostic tests were unavailable. | 2020-10-02 |
| 33006834 | To assess the diagnostic yield of point-of-care ultrasound imaging in patients suspected of having noncritical severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection but no apparent changes on a chest radiograph. […] The sensitivity of point-of-care ultrasound in the diagnosis of COVID-19 was 92.6% (95% CI, 75.7%-99.1%). […] Point-of-care lung ultrasound could be useful for the diagnosis of noncritical SARS-CoV-2 infection when chest radiographs are inconclusive. | 2020-10-02 |
| 33006939 | Health practitioners may provide opportunities to allay concerns or offer coping techniques to individuals in need of mental health care. | 2020-10-02 |
| 33006983 | The ongoing COVID-19 pandemic has created an unprecedented need for rapid diagnostic testing. […] The direct RT-qPCR approach correctly identified 92% of a reference set of blinded NP samples (n = 155) demonstrated to be positive for SARS-CoV-2 RNA by traditional clinical diagnostic RT-qPCR that included an RNA extraction. | 2020-10-02 |
| 33007104 | Adults who received a SARS-CoV-2 test or a COVID-19 diagnosis. | 2020-10-02 |
| 33007131 | However, this number is probably skewed, as the fundamental requirement for a PTSD diagnosis-namely, a life-threatening or severely stressful event-was not fulfilled. […] In this comment, the consideration of COVID-19-related PTSD to represent a diagnosis is questioned based on the definitions of PTSD in the ICD-11 and DSM-5. | 2020-10-02 |
| 33007141 | In a recently published study in this journal that used a population-based sample in the Republic of Ireland (Karatzias et al., 2020), we concluded that 17.7% of the sample met the diagnostic requirements for COVID-19-related posttraumatic stress disorder (PTSD). […] Subsequently, Van Overmeire (2020) has raised concerns about the validity of our findings, arguing that simply experiencing the COVID-19 pandemic is not sufficient to meet the trauma exposure criterion for a PTSD diagnosis and, consequently, our estimated PTSD prevalence figure was inflated. | 2020-10-02 |
| 33007173 | An international multicenter audit of patients with a prior diagnosis of ILD admitted to hospital with COVID-19 between 1 March and 1 May 2020 was undertaken and compared with patients, without ILD obtained from the ISARIC 4C cohort, admitted with COVID-19 over the same period. | 2020-10-02 |
| 33007195 | Currently, there is still a debate on suitable criteria for the diagnosis of patients with sepsis with continuing changes in the guidelines on sepsis management. […] Here we summarize recent advances on the definitions, diagnosis, and treatment in the clinical practice of sepsis management in the emergency department. | 2020-10-02 |
| 33007398 | Accordingly, we reviewed the most critical findings related to the genetics of the SARS-CoV-2, with a specific focus on genetic diversity and reported mutations, molecular-based diagnosis assays, using interfering RNA technology for the treatment of patients, and genetic-related vaccination strategies. | 2020-10-02 |
| 33007999 | We, thus, developed a PNA-based RT-qPCR assay that differentiates emerging pathogens such as SARS-CoV-2 from closely related viruses such as SARSr-CoV and allows diagnosis of infections related to already identified or new coronavirus strains. | 2020-10-03 |
| 33008018 | The objective of this study is to articulate an innovative solution for early diagnosis of COVID-19 symptoms such as abnormal breathing rate, coughing and other vital health problems. […] This study proposes a non-contact sensing platform for the early diagnosis of COVID-19 symptoms and monitoring of the human activities and health during the isolation or quarantine period. | 2020-10-03 |
| 33008081 | We conducted telephone interviews with the participants and evaluated the presence of PTSD using the Post-Traumatic Stress Disorder Checklist-5 (PCL-5) based on the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; score range: 0-80). […] If a score of ≥33 was obtained, then a diagnosis of PTSD was made. | 2020-10-03 |
| 33008459 | Understanding patient’s metabolomics and genetic make-up in conjunction with clinical data will significantly lead to determining predisposition, diagnostic, prognostic, and predictive biomarkers and paths ultimately providing optimal and personalized care for diverse, and targeted chronic and acute diseases. | 2020-10-03 |
| 33008462 | This paper focuses on three types of essential medical products: mechanical ventilators, personal protective equipment (PPE) and diagnostic tests. | 2020-10-03 |
| 33008680 | M-Health (apps) could be a solution in this setting to evaluate a COVID-19 diagnosis. […] We made a review of the diagnosis apps and websites of the different regions of Spain. | 2020-10-03 |
| 33008702 | We analyzed numbers of ambulance calls for all 136 diagnosis codes used by Magen David Adom (MDA), Israel’s national EMS during 121 days between January 01 and April 30, 2020. | 2020-10-03 |
| 33008706 | This case highlights the unique diagnostic and therapeutic challenges associated with treating patients with these concomitant diseases. | 2020-10-03 |
| 33008761 | To review the available literature concerning the effectiveness of the COVID-19 diagnostic tools. […] Although real-time reverse transcription-polymerase chain reaction (RT-PCR) assay is considered the first tool to make a definitive diagnosis of COVID-19 disease, the high false negative rate, low sensitivity, limited supplies and strict requirements for laboratory settings might delay accurate diagnosis. […] Although CT scan is a powerful tool in COVID-19 diagnosis, it is not sufficient to detect COVID-19 alone due to the low specificity (25%), and challenges that radiologists might face in differentiating COVID-19 from other viral pneumonia on chest CT scans. | 2020-10-03 |
| 33009054 | We performed a prospective single-center cohort study, enrolling patients who received diagnosis of COVID-19 at our institution between March 23, 2020, and April 5, 2020. […] Furthermore, we used a specifically designed questionnaire, administered to patients at time of diagnosis, to obtain data on the presence and time of onset of fever, typical respiratory symptoms, gastrointestinal symptoms, and other symptoms (fatigue, headache, myalgia/arthralgia, anosmia, ageusia/dysgeusia, sore throat, and ocular symptoms). […] In our cohort, 138 (69%) of 190 patients showed at least 1 gastrointestinal symptom at diagnosis; if excluding hyporexia/anorexia, 93 patients (48.9%) showed at least 1 gastrointestinal symptom. | 2020-10-03 |
| 33009284 | Gastrointestinal manifestations were common at diagnosis. | 2020-10-03 |
| 33009340 | The relationship of coagulation tests and thrombosis requires investigation to identify best diagnostic and treatment approaches. […] Further work is required to externally validate these findings and to investigate the mechanistic drivers for these relationships to identify best diagnostic and treatment approaches for these patients. | 2020-10-03 |
| 33009727 | The main axes in this direction are establishing vaccines, drugs, diagnostic tests, as well as identifying the most vulnerable groups. | 2020-10-03 |
| 33009735 | Methods were based on The Novel Coronavirus Infected Pneumonia Diagnosis and Treatment Standards. | 2020-10-03 |
| 33009973 | Consecutive patients with diagnosis of neovascular AMD were consecutively enrolled between March 9, 2020, and June 12, 2020, (during and immediately after the Italian COVID-19 quarantine). | 2020-10-03 |
| 33010246 | The rise in search volume for ‘chest pain’ but not ‘heart attack’ or ‘stroke’ may be explained by several hypotheses, including patients being more likely to search for symptoms rather than diagnoses, or it may reflect the reduced hospitalisations for these conditions during the COVID-19 pandemic and hence fewer patients receiving the diagnostic labels ‘heart attack’ and ‘stroke’. | 2020-10-03 |
| 33010669 | Early diagnosis of COVID-19 is the most critical step to treat infection. […] The diagnostic tools are generally molecular methods, serology and viral culture. | 2020-10-03 |
| 33011076 | Administration of CP 20 days after the COVID-19 diagnosis or COVID-19 related symptoms were associated with a higher rate of MV support compared with the first 3 interval groups (≤5 days, 6-10 days, 11-15 days) (p=0.001). | 2020-10-04 |
| 33011274 | Current fluid resuscitation techniques only transiently improve outcomes in sepsis, and can cause edema. | 2020-10-04 |
| 33011281 | We applied statistical methods previously developed to adjust for the delay between diagnosis and death and presented both delay-adjusted and crude (unadjusted) CFRs throughout the epidemic. | 2020-10-04 |
| 33011516 | All consecutive patients admitted with primary diagnosis of ischemic/ hemorrhagic stroke between March1st -May10th 2020 were included and compared with the same time period in 2019. | 2020-10-04 |
| 33011643 | The ongoing SARS-CoV-2 pandemic presents a unique challenge to diagnostic laboratories. | 2020-10-04 |
| 33011877 | To assess inter-reader agreements and diagnostic accuracy of chest CT to identify COVID-19 pneumonia in patients with intermediate clinical probability during an acute disease outbreak. […] Diagnostic accuracy of chest CT compared with RT-PCR assay and patient outcomes was measured using receiver operating characteristics (ROC). […] Inter-observer agreement for highly probable (kappa: 0.83 [p < .001]) and highly probable or probable (kappa: 0.82 [p < .001]) diagnosis of COVID-19 pneumonia was very good. […] During acute COVID-19 outbreak, chest CT scan may be used for triage of patients with intermediate clinical probability with very good inter-observer agreements and diagnostic accuracy. […] • When compared with RT-PCR results and patient outcomes, the diagnostic accuracy of CT to identify COVID-19 pneumonia was high for both radiologists (AUC: 0.94 and 0.92). | 2020-10-04 |
| 33011929 | The aim of this study was to explore the role of lung ultrasound (LUS) in the diagnosis of SARS-CoV-2 infection and to verify its utility in the prediction of lung disease’s severity and outcome. […] Fifty-three consecutive patients presenting to the Emergency Department of Santa Maria delle Grazie Hospital with high suspicion of SARS-CoV-2 infection underwent diagnostic test for SARS-CoV-2 on samples obtained from nasopharyngeal swab as well as complete proper diagnostic work-up that included clinical evaluation, laboratory tests, blood gas analyses, chest CT and LUS. […] Patients were divided into two groups according to the results of both SARS-CoV-2 diagnostic test and other exams (Group A = pneumonia due to SARS-CoV2 infection vs Group B = no SARS-CoV2 infection and another definite diagnosis). […] LUS showed an excellent accuracy in predicting the diagnosis of SARS-CoV-2 infection (area under the ROC curve of 0.92 with a sensibility of 73% and a specificity of 89% a the cut-off of 12.5). | 2020-10-04 |
| 33012053 | Improved protocols for acute febrile illness and access to diagnostic facilities, not just for SARS-CoV-2 but also other viral infections, are of urgent importance. | 2020-10-04 |
| 33012056 | The definition of rigorous and highly effective infection control protocols in the dental settings must therefore be complemented by the development and strengthening of remote communication techniques with the parents, who must be adequately educated on preventive and palliative measures for the management of their children’s oral health, with the aim of postponing clinical attendance to when the circumstances become favourable. […] The experience gained with these approaches and models of treatment, where remote interaction techniques play a central role, will hone the communication skills of the paediatric dentist and will retain its usefulness even at the end of the current emergency period. | 2020-10-04 |
| 33012174 | As we adapt to function in the era of Coronavirus Disease 2019 (COVID-19) a better understanding of how surgical techniques generate potentially infectious aerosolized particles will enhance the safety of operating room (OR) staff and learners. | 2020-10-05 |
| 33012282 | We compared the numbers of medical visits performed, antiretroviral drugs dispensed and the number of new HIV diagnosis and of hospitalizations in a cohort of people living with HIV (PLWH) followed by the Spedali Civili of Brescia between the bimester of the COVID-19 pandemic peak and the bimester of October-November 2019. […] Comparing the two periods, we observed a raise of missed visits from 5 to 8% (p < 0.01), a reduction in the number of new HIV diagnosis from 6.4 in 2019 to 2.5 per month in 2020 (p = 0.01), a drop in ART dispensation and an increase of hospitalized HIV patients due to COVID-19. | 2020-10-05 |
| 33012341 | The primary outcome was a composite of mechanical ventilation or death 48 hours from diagnosis. | 2020-10-05 |
| 33012653 | Fungus culture and galactomannan test, especially from respiratory specimens could help early diagnosis. | 2020-10-05 |
| 33012721 | We discuss the presentation, investigations, differential diagnosis and management. | 2020-10-05 |
| 33012834 | Imaging of the lung is absolutely necessary to obtain a diagnosis, assess the course of disease and for treatment. | 2020-10-05 |
| 33013059 | Diagnosis is primarly made by detecting viral RNA by reverse transcriptase polymerase chain reaction (rtPCR) in nasopharyngeal swab samples. | 2020-10-05 |
| 33013686 | All patients with a laboratory confirmed COVID-19 diagnosis in March 2020 in a large New York City health system were reviewed. | 2020-10-05 |
| 33013857 | Ongoing efforts to control the pandemic include the development of peptide-based vaccines and diagnostic tests. […] In conclusion, the candidate epitopes presented provide valuable information for the development of epitope-based strategies against SARS-CoV-2, such as peptide vaccines and diagnostic tests. | 2020-10-05 |
| 33014121 | The COVID-19 diagnostic approach is mainly divided into two broad categories, a laboratory-based and chest radiography approach. […] The last few months have witnessed a rapid increase in the number of studies use artificial intelligence (AI) techniques to diagnose COVID-19 with chest computed tomography (CT). […] In this study, we review the diagnosis of COVID-19 by using chest CT toward AI. | 2020-10-05 |
| 33014150 | This review emphasize on the origin of the coronoviral epidemics, discussion on the structural and functional basis of SARS-CoV-2, epidemiology, pathognomonic symptoms, fatality, available rapid diagnostic methods and proposed possible treatment methods for the treatment of COVID-19. […] The diagnostic markers with respect to genetic material of the virus based on PCR, CRISPR & APTAMER and with respect to proteins based on Antigens were discussed which provides new arena for the development. | 2020-10-05 |
| 33014210 | This study was aimed to investigate the application of SARS-CoV-2 IgM and IgG antibodies in diagnosis of COVID-19 infection. […] Combined detection of serum SARS-CoV-2 IgM and IgG antibodies had better sensitivity compared with single IgM or IgG antibody testing, which can be used as an important diagnostic tool for SARS-CoV-2 infection and a screening tool of potential SARS-CoV-2 carriers in clinics, hospitals, and accredited scientific laboratories. | 2020-10-05 |
| 33014253 | Since asymptomatic infections as “covert transmitter”, and some patients can progress rapidly in the short term, it is essential to pay attention to the diagnosis and surveillance of asymptomatic patients with SARS-COV2 infection. | 2020-10-05 |
| 33014283 | In the COVID-19 era, oncologists obtaining routine staging imaging should have high diagnostic suspicion for subclinical SARS-CoV-2 infection. | 2020-10-05 |
| 33014475 | This case highlights some of the diagnostic and therapeutic challenges presented by COVID-19 pandemic. | 2020-10-05 |
| 33014657 | Materials and methods This manuscript details the process of the establishment of a COVID-19 lab, which is a medical college virology lab (Viral Research Diagnostic Lab), in less than a months’ time. | 2020-10-05 |
| 33014710 | A focus on resource preservation can result in anchoring bias and missed concurrent diagnosis. | 2020-10-05 |
| 33014718 | The infection is often asymptomatic and atypical in children, while overlapping presentations with other infectious diseases generate additional diagnostic challenges. | 2020-10-05 |
| 33014801 | The consensus highlighted a multidisciplinary team diagnostic model with assessment of the balance between risks and benefits prior to treatment, individualizing satisfaction of patients’ medical needs, and acceptability in ethics and patients’ socio-economic conditions. | 2020-10-05 |
| 33014893 | Objective: To explore the diagnostic value of serum severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid (N) protein assay in the early stages of SARS-COV-2 infection. […] Conclusion: The measurement of serum SARS-COV-2 N protein has a high diagnostic value for infected patients before the antibody appears and shortens the window period of serological diagnosis. […] One CUT-OFF value is used for the diagnosis of clinical SARS-COV-2 infection, and the other is used to screen out as many suspected cases as possible. | 2020-10-05 |
| 33014984 | Our study resulted in the following mainstays of Iran’s approach to COVID-19: (i) active clinical screening; preferably on-line or on-phone, (ii) management of limited paraclinical resources; by using them as diagnostic tools rather than epidemiological, (iii) a trend toward outpatient care of mild-to-moderate cases; either confirmed or suspicious, with active scheduled follow-up, and (iv) avoidance of pharmacotherapy, as far as possible. | 2020-10-05 |
| 33015100 | Limited availability of high-resolution computed tomography and real-time polymerase chain reaction in developing countries and regions of high patient turnover also emphasizes the importance of chest radiography as both a screening and diagnostic tool. […] We utilize an existing diagnostic technology (chest radiography) and preexisting neural networks (DarkNet-19) to detect imaging features of COVID-19 pneumonia. | 2020-10-05 |
| 33015110 | Conclusion: The viral load of COVID-19 is negatively correlated with an uneasily differentiated lesion margin on initial CT scan images and the Ct value should noted when making a diagnosis. […] In addition, following-up CT scans are necessary for patients who presented a normal CT at the initial diagnosis, especially for those with a low Ct value. | 2020-10-05 |
| 33015267 | To achieve this aim, a methodology is proposed based on the Pareto analysis, fuzzy theory, total interpretive structural modelling (TISM), and Matriced Impacts Cruoses Multiplication Applique a un Classement techniques (MICMAC). | 2020-10-05 |
| 33015361 | Short-term efforts have focused on re-purposing existing technologies and leveraging additive manufacturing techniques to address shortages in personal protective equipment and disinfection. | 2020-10-05 |
| 33015551 | This is a retrospective cohort study that analyzed patients admitted to a community academic hospital with the diagnosis of Covid-19. | 2020-10-05 |
| 33015554 | The following data by prefecture were abstracted from open resources provided by the Ministry of Health, Labour and Welfare in Japan as of May 24, 2020: total number of COVID-19 deaths; polymerase chain reaction (PCR)-positive ratio (i.e., number of patients with PCR-positive results/number of patients aiming diagnosis of COVID-19 or individuals in close contacted with COVID-19 patients); number of call centers, outpatient centers, and hospital beds specifically for patients diagnosed with COVID-19; and others. | 2020-10-05 |
| 33015645 | We aimed to develop and validate diagnostic criteria for cHIS in a cohort of inpatients with COVID-19. […] We searched for clinical research articles published between Jan 1, 1990, and Aug 20, 2020, on features and diagnostic criteria for secondary haemophagocytic lymphohistiocytosis, macrophage activation syndrome, macrophage activation-like syndrome of sepsis, cytokine release syndrome, and COVID-19. | 2020-10-05 |
| 33015712 | The sensitivities and false-negative rates of the 239 specimens that met inclusion criteria were, respectively, as follows: Centers for Disease Control and Prevention 2019 nCoV Real-Time RT-PCR Diagnostic Panel, 100% and 0%; TIB MOLBIOL/Roche z 480 Assay, 96.5% and 3.5%; Xpert Xpress SARS-CoV-2 (Cepheid), 97.6% and 2.4%; Simplexa COVID-19 Direct Kit (DiaSorin), 88.1% and 11.9%; and ID Now COVID-19 (Abbott), 83.3% and 16.7%. | 2020-10-05 |
| 33015816 | Otolaryngologists, ophthalmologists and dentists are at high risk for infection contagion and spread because they perform diagnostic and therapeutic procedures that generate aerosol and droplets thus facilitating virus transmission. […] Special attention to prevention protocols for diagnostic and therapeutic procedures and the use of protective equipment is of utmost importance to limit contagion and prevent a new virus spread in the near future. | 2020-10-05 |
| 33015866 | Many recently published studies have evaluated incidence of PE in hospitalized patients with COVID-191-9 , however there is relatively limited data describing patients with SARS-CoV-2 infection and concomitant diagnosis of acute PE upon initial presentation. | 2020-10-05 |
| 33016144 | Additional diagnostic screening was performed in eight banks, using conjunctival swabs and/or nasopharyngeal swabs. | 2020-10-05 |
| 33016187 | Safety outcomes were measured based on the diagnostic concordance between physicians. […] In terms of safety, telemedicine achieved a mean diagnostic concordance of 92.8% compared to in-person consultations. | 2020-10-05 |
| 33016788 | This integrative model is holistic, recognising humans as bio-psycho-social-spiritual beings and considers several theoretical perspectives in both diagnosis and treatment. | 2020-10-05 |
| 33017040 | Here we examined, using ELISA, the IgG antibodies in serum specimens collected from 17 COVID-19 patients at 6-7 months after diagnosis and the results were compared to those from cases investigated 2 weeks to 2 months post-infection. | 2020-10-05 |
| 33017067 | Measurements were taken at time points throughout diagnostic and debridement endoscopies and compared to preprocedure and empty room particle concentrations. […] No significant change in airborne particle concentrations was measured during diagnostic nasal endoscopies in patients without the need for debridement. […] When measured with an optical particle sizer, diagnostic nasal endoscopy with a rigid endoscope is not associated with increased particle aerosolization in patient for whom sinonasal debridement is not needed. | 2020-10-05 |
| 33017232 | Legislation in Ohio established a unique health-transportation partnership among the State of Ohio, Children’s Hospital of Philadelphia, and Diagnostic Driving, Inc., to identify underprepared driver license applicants through a virtual driving assessment system. | 2020-10-05 |
| 33017280 | It also covers the basics about the disease immunopathogenesis, diagnosis, prognosis, and treatment options. | 2020-10-05 |
| 33017480 | In this prospective observational study, consecutive patients hospitalized in the internal medicine ward with a diagnosis of COVID-19 who developed PE were screened for DVT in the lower extremities with complete compression ultrasound. | 2020-10-05 |
| 33017697 | Clinical data were extracted from electronic medical records in 1550 patients with laboratory-confirmed diagnosis of COVID-19 who hospitalized in Wuhan Central Hospital, China, from 1 January to 31 April, 2020. […] 30 COVID-19 patients with the diagnosis of epilepsy were enrolled. […] Of 30 patients with diagnosis of epilepsy and COVID-19, 13 patients(43.4%) had new-onset epileptic seizure without epilepsy history(new-onset seizure group,NS group), 10 patients(33.3%) with epilepsy history had recurrent epileptic seizure(recurrent seizure group,RS group) and 7 patients(23.3%) with epilepsy history had no seizure during the course of COVID-19 (epilepsy history group,EH group). | 2020-10-05 |
| 33017835 | It is possible to speculate that this is the consequence of a delayed diagnosis and deferred treatment of acute conditions. | 2020-10-05 |
| 33017910 | The main port of entry for the virus is the upper respiratory tract, and the diagnosis is usually by PCR of the viral RNA with nasal and pharyngeal swab test. | 2020-10-06 |
| 33019426 | A systematic review of peer-reviewed literature published through March 31, 2020 was performed to estimate the mortality rate among hospitalized patients in China with a confirmed diagnosis of Covid-19. […] The review included 16 observational studies involving 1832 hospitalized patients with a diagnosis of Covid-19. […] In a meta-analysis of hospitalized patients in China with a diagnosis of Covid-19, the mortality rate was 9.9% and a higher diabetes mellitus prevalence was independently associated with a worse prognosis. | 2020-10-06 |
| 33019514 | Mean age, sex, triage urgency level, day/night admission, main presentation symptom, and final diagnosis, according to different medical specialties, hospitalization, and discharge rate, were analyzed. | 2020-10-06 |
| 33019920 | For diagnosis of coagulopathy, mainly Ddimer, but also PT, APTT and FDP, should be evaluated in COVID-19 patients. | 2020-10-06 |
| 33019921 | As a result, new techniques have been proposed to streamline this process. | 2020-10-06 |
| 33020043 | Here, we investigated the diagnostic performance of chest computed tomography (CT) as an alternative to RT-PCR in patients with clinical suspicion of COVID-19 infection. […] CT findings were considered as positive/negative for COVID-19 infection based on RSNA diagnostic criteria. […] Low-dose chest CT is a safe, rapid and reliable alternative to RT-PCR for the diagnosis of COVID-19 in high-prevalence regions. | 2020-10-06 |
| 33020186 | Sensitive and specific SARS-CoV-2 serologic assays are needed to inform diagnostic, therapeutic, and public health decision-making. […] Pairing two different serologic tests in a two-test algorithm improves PPV compared with the individual assays alone, while maintaining NPV. | 2020-10-06 |
| 33020224 | To monitor hospital activity for presentation, diagnosis and treatment of cardiovascular diseases during the COVID-19) pandemic to inform on indirect effects. | 2020-10-06 |
| 33020333 | Patients with autoimmune disease were asked about demographic characteristics, diagnosis, history of treatment, knowledge, perception, and practice regarding COVID-19. there were 685 respondents. | 2020-10-06 |
| 33020339 | The presence of unspecified initial symptoms calls for greater vigilance from health workers in establishing diagnosis patients with COVID-19. | 2020-10-06 |
| 33020719 | The WHO and countries with severe outbreaks have developed diagnosis and treatment guidelines. […] Using the diagnosis and treatment guidelines of the WHO and the United States and China as examples, we evaluate the transformation of scientific results from basic research to applications. […] COVID-19 has fostered interdisciplinary cooperative research, and the current results are mainly focused on the origin, epidemiological characteristics, clinical research, and diagnosis and treatment methods for the virus. […] Due to the ongoing publication of new research, diagnosis and treatment guidelines are constantly improving. | 2020-10-06 |
| 33020733 | We performed acute and subacute emergencies which include diagnosis and treatment of malignant tumors of the head and neck, management of airway emergencies in adults and children, drainage of abscesses of the head and neck, Foreign body removal, emergency nasal debridement and surgeries for the unsafe ear. | 2020-10-06 |
| 33020734 | A total of 218 patients (13%) received a diagnosis of possible COVID-19, with SARS-CoV-2 infection confirmed in 18.4%, and 23.8% (52/218) were hospitalised. | 2020-10-06 |
| 33020762 | Over the last few months of global hurry to optimize a testing strategy, it has been suggested that bedside point-of-care lung ultrasound may have a diagnostic role. | 2020-10-06 |
| 33020999 | We hypothesize that concern about presenting to hospital during a pandemic led to a delay in diagnosis. | 2020-10-06 |
| 33021087 | The aim of this narrative review was to collect all findings from literature about oral signs and symptoms of COVID-19, in order to draw a picture of oral involvement of this challenging viral infection, to help oral professionals in a better triage and early diagnosis. […] The search for international literature was made including articles written in English and reporting about oral manifestations in patients with a diagnosis of COVID-19. | 2020-10-06 |
| 33021131 | We conducted a prospective observational study between April 22nd and May 26th, 2020 where all adult patients with the diagnosis of Covid-19 pneumonia admitted to 8 ICUs of Montefiore Medical Center were included. | 2020-10-06 |
| 33021206 | Diagnosis of SARS-COV-2 infection (COVID-19) is currently based on detection of the viral RNA in nasopharyngeal swab samples by reverse transcription polymerase chain reaction (RT-PCR). […] Given that the disease is transmitted via exhaled aerosol and droplets, and that the exhaled breath condensate (EBC) is the established modality for sampling exhaled aerosol, detection of the viral RNA in EBC is a promising approach for safe and efficient diagnosis of the disease. | 2020-10-06 |
| 33021553 | Limited data, non-specific symptoms, non-responsiveness to antibiotics, and the lack of a specific biomarker, make it a diagnosis of exclusion. […] Overlap of clinical and imaging findings with other ongoing respiratory illness (MERS, SARS and CoVid-19) poses a challenge in accurate diagnosis. | 2020-10-06 |
| 33022019 | Public health emergency of SARS-CoV-2 has facilitated diagnostic testing as a related medical countermeasure against COVID-19 outbreak. […] None of these methods, however, are useful in early diagnosis of SARS-CoV-2. | 2020-10-06 |
| 33022093 | These novel findings from real-time aerosol detection in a routine healthcare setting provide a quantitative methodology for risk assessment that can be extended to other airway management techniques and clinical settings. | 2020-10-06 |
| 33022374 | In addition, other studies have shown that many deceased patients have diagnostic criteria for disseminated intravascular coagulation (DIC) set by the International society of hemostasis and thrombosis (ISTH). | 2020-10-06 |
| 33023417 | The explosive spread of the virus and the rapid increase in the number of cases require the immediate development of effective therapies and vaccines as well as accurate diagnosis tools. | 2020-10-07 |
| 33023671 | Serum for SARS-Cov-2 diagnostic is collected at baseline and subsequently at day 3, 7, 14 and once during the follow-up period (between day 35 and day 84). | 2020-10-07 |
| 33023798 | The endpoints for evaluating mortality for all participants were death, 21 days after diagnosis, or April 10, 2020. | 2020-10-07 |
| 33023853 | In the field of transfusion medicine, many pathogen reduction techniques (PRTs) are currently available, including those based on photochemical (PI) and photodynamic inactivation (PDI). | 2020-10-07 |
| 33023916 | Here, we used mathematical modeling to predict the trend of patient diagnosis outside China in future, with the aim of easing anxiety regarding the emergent situation. […] According to all diagnosis number from WHO website and combining with the transmission mode of infectious diseases, the mathematical model was fitted to predict future trend of outbreak. […] Daily diagnosis numbers from countries outside China were downloaded from WHO situation reports. | 2020-10-07 |
| 33024072 | The sensitivity analysis revealed that the SARS group was associated with anxiety, depression, sleep disorders, PTSD/ASD, and suicide after the individuals with a diagnosis of psychiatric disorders and suicide were excluded within the first year, and with anxiety, depression, and sleep disorders, while those in the first five years were excluded. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024174 | However, the magnitude of the COVID-19 pandemic is causing disruptions to the global supply chains used by many diagnostic laboratories to procure the commercial kits required for RNA extraction. […] Most importantly, this procedure can be easily implemented in any molecular diagnostic laboratory. | 2020-10-07 |
| 33024341 | A high sensitivity and modest specificity were documented, and this later decreased during the COVID-19 outbreak, as well as its diagnostic accuracy. | 2020-10-07 |
| 33024412 | The control of spreading of COVID-19 in emergency situation the entire world is a challenge, and therefore, the aim of this study was to propose a spherical intelligent fuzzy decision model for control and diagnosis of COVID-19. | 2020-10-07 |
| 33024749 | For this reason, diagnostic tools, patient management and therapeutic approaches have been tested along the way, in the desperate race to break free from the widespread infection and its fatal respiratory complications. | 2020-10-07 |
| 33025305 | Endomyocardial biopsy represents the diagnostic gold standard for its diagnosis but is infrequently used. […] Due to its noninvasive ability to detect the presence of myocardial edema, hyperemia and necrosis/fibrosis, Cardiac MR imaging is routinely used in the clinical practice for the diagnosis of acute myocarditis. […] Our paper will review the role of MR imaging in the diagnosis of acute myocarditis. | 2020-10-07 |
| 33025386 | Machine learning algorithms built on radiography images can be used as a decision support mechanism to aid radiologists to speed up the diagnostic process. | 2020-10-07 |
| 33025463 | AF in cardio-oncology poses diagnostic and management challenges, also due to the number of anticancer drugs recently associated with AF onset/worsening. | 2020-10-07 |
| 33025500 | Residents were studied clinically 4 weeks after the first COVID diagnosis. […] The rapid dissemination of the COVID-19 infection may be explained by the delay in the diagnosis of the first cases due to atypical presentation. | 2020-10-07 |
| 33025502 | Among COVID-19 patients, diagnosis of PE was performed at admission in 38% (n=8). […] COVID-19 patients with diagnosis of PE during hospitalization (n=13) had significantly more dyspnea (p=0.04), lower arterial oxygen saturation (p=0.01), less proximal PE (p=0.02), and higher heart rate (p=0.009), CT severity score (p=0.001), C-reactive protein (p=0.006) and WBC count (p=0.04). | 2020-10-07 |
| 33025503 | Other than these PCR based methods, some improved methods also exist such as microarray-based techniques, Real time-quantitative PCR, CRISPR-Cas13 based tools but almost all of the available methods have advantages and disadvantages. […] There are many limitations associated with this method and hence there is a need for a fast, more sensitive, and specific diagnostic tool which can detect a greater number of samples in less time. […] Here we have summarised currently available nucleic acid-based diagnostic methods for the detection of coronavirus and the need for developing a better technique for a fast and sensitive detection of coronavirus infections. | 2020-10-07 |
| 33025540 | Most surgeons would not change usual algorithms or techniques. | 2020-10-07 |
| 33026198 | Interpreting serological tests is not easy; the strategies for diagnosis should include clinical and epidemiological history and clinical manifestations, as well as the results of confirmation tests and the evaluation over a precise observation period. | 2020-10-07 |
| 33026202 | In our short experience we have used continuous techniques (CRRT) in positive patients hemodynamically unstable and intermittent dialysis (IRRT) in our stable chronic patients with asymptomatic COVID -19. | 2020-10-07 |
| 33026219 | This study assessed the impact of a recent (within past year) diagnosis of a mental disorder - including attention-deficit/hyperactivity disorder (ADHD), bipolar disorder, depression and schizophrenia - on the risk for COVID-19 infection and related mortality and hospitalization rates. […] Patients with a recent diagnosis of a mental disorder had a significantly increased risk for COVID-19 infection, an effect strongest for depression (adjusted odds ratio, AOR=7.64, 95% CI: 7.45-7.83, p<0.001) and schizophrenia (AOR=7.34, 95% CI: 6.65-8.10, p<0.001). […] Among patients with a recent diagnosis of a mental disorder, African Americans had higher odds of COVID-19 infection than Caucasians, with the strongest ethnic disparity for depression (AOR=3.78, 95% CI: 3.58-3.98, p<0.001). […] Patients with both a recent diagnosis of a mental disorder and COVID-19 infection had a death rate of 8.5% (vs. […] These findings identify individuals with a recent diagnosis of a mental disorder as being at increased risk for COVID-19 infection, which is further exacerbated among African Americans and women, and as having a higher frequency of some adverse outcomes of the infection. | 2020-10-07 |
| 33026346 | In addition, in countries located in tropical or intertropical zones, the diagnosis of COVID-19 is complicated by the presence of various zoonoses (dengue, Zika, malaria, leptospirosis, etc.). | 2020-10-07 |
| 33026628 | A uniform COVID-19 post-mortem diagnostic protocol has not yet been developed. […] In a time in which international collaboration is essential, standardized diagnostic criteria are fundamental requirements. | 2020-10-07 |
| 33026711 | Importantly, radiographers have been identified as having a high-risk role and have had to modify positioning techniques and cleaning regimes accordingly. | 2020-10-07 |
| 33027033 | This study aims to explore the feasibility of telemedicine for the diagnosis of all otologic disease types. […] Asynchronous diagnoses were made for each patient to assess Top-1 and Top-2 accuracy, and we selected 20 cases to conduct a survey among four different otolaryngologists to assess the accuracy, interrater agreement, and diagnostic speed. […] We also constructed an experimental automated diagnosis system and assessed Top-1 accuracy and diagnostic speed. […] Asynchronous diagnosis showed Top-1 and Top-2 accuracies of 77.40% and 86.44%, respectively. […] The automated diagnostic model system showed 69.50% Top-1 accuracy. […] Moreover, enhanced diagnostic speed while sustaining the accuracy shows the possibility of optimizing medical resources to provide expertise in areas short of physicians. | 2020-10-07 |
| 33027042 | The diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection globally has relied extensively on molecular testing, contributing vitally to case identification, isolation, contact tracing, and rationalization of infection control measures during the coronavirus disease 2019 (COVID-19) pandemic. | 2020-10-07 |
| 33027043 | While regulatory approved serological immunoassays are now widely available from diagnostic manufacturers globally, there is significant debate regarding the clinical utility of these tests, as well as their clinical and analytical performance requirements prior to application. | 2020-10-07 |
| 33027152 | Lessons learned include: the need to develop and deploy valid tests for point-of-care diagnosis and surveillance; the importance of considering HIV and COVID-19 in the context of syndemics; the potential role of structural interventions that address drivers of disparities; how existing research infrastructure can be leveraged to accelerate development of therapeutics and vaccines; and how modeling that is tailored to regional epidemics can inform policy. | 2020-10-07 |
| 33027349 | We investigated the predictors of delay in the diagnosis and mortality of patients with COVID-19 in Rio de Janeiro, Brazil. […] A cohort of 3,656 patients were evaluated (Feb-Apr 2020) and patients’ sociodemographic characteristics, and social development index (SDI) were used as determinant factors of diagnosis delays and mortality. […] The median time from symptoms onset to diagnosis was eight days (interquartile range [IQR] 7.23-8.99 days). […] Delays in diagnosis were associated with male gender (p = 0.015) and patients living in low SDI areas (p < 0.001). […] Delays to diagnosis greater than eight days were also risk factors for death. […] Delays in diagnosis and risk factors for death from COVID-19 were associated with male gender, age under 60 years, and patients living in regions with lower SDI. […] Delays superior to eight days to diagnosis increased mortality rates. | 2020-10-07 |
| 33027351 | Thus, participants with previous diagnosis of depression were at risk for incidence of unhealthy diet behaviors. | 2020-10-07 |
| 33027418 | These aspects are relevant for correct diagnosis and treatment, and for the potential development of vaccines. | 2020-10-07 |
| 33027434 | Lastly, a spatial dependence diagnosis was conducted, and a Spatial Regression lag model was used when applicable. | 2020-10-07 |
| 33027775 | The outbreak of coronavirus SARS-COV2 affected more than 180 countries necessitating fast and accurate diagnostic tools. […] However, radiological solutions have not been used extensively for the diagnosis of COVID-19 disease, partly due to radiation risk. […] Notwithstanding other aspects of diagnosis, the present results capture a component of risk consideration associated with the use of imaging for COVID. […] Once integrated with other diagnostic factors, they may help inform better management of the pandemic. | 2020-10-07 |
| 33028403 | This case emphasizes the importance of repeat polymerase chain reaction testing and diagnosis based on multiple criteria, including clinical symptoms and computed tomographic imaging findings. | 2020-10-08 |
| 33028570 | After ruling out COVID-19 infection, a diagnosis of chronic obstructive pulmonary disease exacerbation was confirmed and he was thus transferred to the nephrology division. | 2020-10-08 |
| 33028572 | After diagnostic investigations, Ewing’s sarcoma with metastatic pulmonary dissemination was diagnosed. | 2020-10-08 |
| 33028689 | Since asymptomatic patients have no clinical symptoms which can easily prevent timely diagnosis and treatment, they may cause a greater risk of virus transmission than symptomatic patients, which poses a major challenge to infection control. | 2020-10-08 |
| 33028754 | In conclusion, leucocytes, leucocyte fractions, CRP, LDH, and electrolytes are useful indicators for COVID-19 diagnosis. | 2020-10-08 |
| 33028802 | This is an uncommon condition, with the potential for missed diagnosis and potential harm to the patient. | 2020-10-08 |
| 33029064 | COVID-19 has presented numerous challenges to all aspects of health care, including reliable methods for diagnosis, treatment, and prevention. […] Initial efforts to contain the spread of the virus were hampered by the time required to develop reliable diagnostic methods. […] We have used a readily available, commercial platform to demonstrate the potential of AI to assist in the successful diagnosis of COVID-19 pneumonia on CXR images. […] The findings have implications for screening and triage, initial diagnosis, monitoring disease progression, and identifying patients at increased risk of morbidity and mortality. | 2020-10-08 |
| 33029098 | Furthermore, the differential diagnosis between COVID-19 pneumonia and radiation pneumonitis in cancer patients remains a challenge. […] Conclusions: Lung CT imaging combined with clinical and laboratory findings can facilitate early diagnosis and appropriate management of COVID-19 pneumonia with a history of malignancy and radiation therapy. | 2020-10-08 |
| 33029489 | We aimed to summarize reliable medical evidence by the meta-analysis of all published retrospective studies that examined data based on the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by clinical symptoms, molecular (RT-PCR) diagnosis, and characteristic CT imaging features in pregnant women. […] RT-PCR and CT can be used together in an accurate and safe diagnosis. | 2020-10-08 |
| 33029522 | There is a shortage of chemical reagents for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnosis and a surge of SARS-CoV-2 cases, especially in limited-resource settings. | 2020-10-08 |
| 33029657 | Using a highly specific and sensitive measurement of antibodies by fluid-phase luciferase immunoprecipitation assays, we characterised the IgG, IgM and IgA response against multiple antigens of SARS-CoV-2 in a cohort of 509 patients with documented diagnosis of COVID-19, prospectively followed at our institution. […] Moreover, a strong association between higher glucose levels and risk of death was documented irrespective of diabetes diagnosis (HR 1.14 × 1.1 mmol/l [95% CI 1.08, 1.21], p < 0.001). | 2020-10-08 |
| 33030102 | In this scenario, computer-aided drug design techniques can be efficiently applied for the quick identification of promising drug repurposing candidates. | 2020-10-08 |
| 33030200 | In order to cope with the rapid spread of the COVID-19 pandemic, we introduced on our in-house high-throughput molecular diagnostic platform (MDx Platform) a real-time reverse transcriptase PCR (RT-PCR) to detect the SARS-CoV-2 from any clinical specimens. […] The high agreements between the cobas SARS-CoV-2 test and the MDx platform supports the use of both methods for the diagnostic of COVID-19 on various clinical samples. | 2020-10-08 |
| 33030591 | Even during the COVID-19 pandemic, psychological treatment enables the increased stress level in headache patients to be counteracted by using cognitive behavioral therapy and relaxation techniques. […] With respect to content, stress regulation techniques and increased acceptance gain in importance. | 2020-10-08 |
| 33030622 | Diagnosis, treatment strategy, and timing were compared between the two cohorts to define temporal trends. | 2020-10-08 |
| 33031048 | RT-PCR testing for the identification of viral nucleic acid is the current standard diagnostic method for the diagnosis of SARS-CoV-2 infection but technical reasons limit its utilization for large-scale screening. […] The rapid serological test analyzed in the present study seems of limited usefulness for the diagnosis of SARS-CoV-2 infection but it is a candidate test for providing relevant information on the immunoreaction of subjects to COVID-19 exposure. | 2020-10-08 |
| 33031081 | All cases were diagnosed with COVID-19 nucleic acid positive by using RT-PCR or clinical manifestations, imaging specific characteristics and epidemiological clinical diagnosis. | 2020-10-08 |
| 33031087 | Due to COVID-19 epidemic evolution, particularly in Cabo Delgado, there is the need to increase laboratory diagnosis capacity and monitor compliance of preventive measures. | 2020-10-08 |
| 33031143 | Most neonates were admitted with diagnosis unrelated to SARS-CoV-2: 11 presented with serious non-communicable diseases, 7 with early-onset sepsis, 5 with late-onset sepsis and 2 with pneumonia. | 2020-10-08 |
| 33031341 | High-quality synthesis and/or descriptive analysis of current evidence will be provided from the time of negative nucleic acid detection for 2 consecutive times (not on the same day), cure rate, converting to clinical diagnosis rate, and side effects of acupuncture. | 2020-10-08 |
| 33031358 | A total of 22,016 patients with diagnostic confirmation for COVID-19 caused by SARS-CoV-2 were analyzed between March 4 and May 5, 2020, nationwide. | 2020-10-08 |
| 33031439 | This study included all consecutive patients admitted for COVID-19 between February and April 2020 at Imperial College Healthcare NHS Trust, with either imaging of the liver available dated within one year from the admission or a known diagnosis of NAFLD. […] NAFLD diagnosis was based on imaging or past medical history and patients were stratified for Fibrosis-4 (FIB-4) index. […] NAFLD diagnosis was not associated with adverse outcomes. | 2020-10-08 |
| 33031464 | Changes in the delivery of diagnostics (diagnostic endoscopy), imaging for staging, therapeutics and surgical technique in the management of colorectal cancer. […] Diagnostic endoscopy was reduced in 93% of responses, even with low hospital stress and mortality; whilst rising critical care bed stress triggered complete cessation (p = 0.02). | 2020-10-08 |
| 33031651 | Regular screening of medical personnel involved in the diagnosis and treatment of patients with COVID-19 should be conducted to evaluate for stress, anxiety, and depression. | 2020-10-08 |
| 33031760 | In this retrospective observational study, we collected demographic data, mental health diagnoses, clinical diagnosis of COVID-19, symptoms, management, and COVID-19-related outcome data of inpatients aged 65 years or older or with dementia who were already inpatients or admitted as inpatients to five London mental health Trusts between March 1 and April 30, 2020, and information about available COVID-19-related resources (ie, testing and personal protective equipment). | 2020-10-08 |
| 33031947 | Rapid, reliable, and easy-to-implement diagnostics that can be adapted in early SARS-CoV-2 diagnosis are critical to combat the epidemic. […] However, the accuracy of this diagnostic method needs to be examined. […] The diagnostic accuracy of NP antigen testing was calculated by taking NA testing of RT-PCR as reference standard, in which samples with cycle threshold (Ct) value ≤ 40 were interpreted as SARS-CoV-2 positives. […] Of 251 participants (99.2%) that were included in the diagnostic accuracy analysis, a total of 201 participants (80.1%) had a Ct value ≤40. […] With RT-PCR assay as reference standard, NP antigen testing by FIC assay shows high specificity and relative high sensitivity in SARS-CoV-2 diagnosis in the early phase of infection. | 2020-10-08 |
| 33032267 | Moreover, several chest CT image features and laboratory indices are found to be important to COVID-19 severity, which could be valuable for the clinical diagnosis of COVID-19. | 2020-10-08 |
| 33032333 | Many dental practitioners cannot distinguish the correct diagnostic features of oral infections particularly viral and fungal infections. | 2020-10-08 |
| 33032681 | Of these, 108 (16.2%) had direct contact with people with a COVID-19 diagnosis. […] Direct contact with people with a COVID-19 diagnosis (P<0.001) and being a nurse or midwife (P<0.001) were associated with higher anxiety scores. […] Australia healthcare providers have experienced considerable emotional distress during the COVID-19 pandemic, particularly nurses and midwives and clinical staff who have had direct contact with people with a COVID-19 diagnosis. | 2020-10-09 |
| 33032981 | Chest computed tomography (CT) continues to play an important role in the diagnosis and follow-up of the disease due to shortcomings of the real-time reverse transcription-polymerase chain reaction test, which is the gold standard in the diagnosis of this disease. | 2020-10-09 |
| 33033166 | The decreased accessibility of the medical services and postponed diagnosis of potentially curable cancers during the COVID-19 pandemic may be a step backwards in our healthcare system and might impair cancer treatment outcomes. | 2020-10-09 |
| 33033346 | Thus we explored the plasma metabolome of patients infected with SARS-CoV-2 to search for diagnostic and/or prognostic biomarkers and to improve the knowledge of metabolic disturbance in this infection. […] We analyzed the plasma metabolome of 55 patients infected with SARS-CoV-2 and 45 controls by LC-HRMS at the time of viral diagnosis (D0). […] We first evaluated the ability to predict the diagnosis from the metabotype at D0 in an independent population. […] Plasma metabolome allowed us to generate a discriminant multivariate model to predict the diagnosis of SARS-CoV-2 in an independent population (accuracy > 74%, sensitivity, specificity > 75%). […] Here, we present the first metabolomic study in SARS-CoV-2 patients which showed a high reliable prediction of early diagnosis. | 2020-10-09 |
| 33033486 | A structured telephone interview was delivered to family caregivers of patients with diagnosis of Alzheimer disease (AD), dementia with Lewy bodies (DLB), frontotemporal dementia (FTD), and vascular dementia (VD), followed regularly at 87 Italian memory clinics. […] Anxiety and depression were associated with a diagnosis of AD (OR 1.35, CI: 1.12-1.62), mild to moderate disease severity and female gender. | 2020-10-09 |
| 33033574 | Since imaging not only helps assess the disease at the time of diagnosis but also aids evaluation of response to management, it is critical to examine the role of different modalities currently in use, such as baseline X-rays and computed tomography scans carefully. […] Further, we will look at point of care ultrasound, an increasingly a popular tool in diagnostic medicine, as a component of COVID-19 management. | 2020-10-09 |
| 33033700 | These challenges may lead to difficulties in meeting protocol-specified procedures, including administering or using the investigational product or adhering to protocol-scheduled visits and laboratory/diagnostic testing. | 2020-10-09 |
| 33033827 | We also quantified the improvement in the TDI score based on initial diagnosis. | 2020-10-09 |
| 33033955 | These symptoms might be a useful tool for initial diagnostic work-up in patients with suspected COVID-19. | 2020-10-09 |
| 33034046 | We evaluate temperature trends among nursing home (NH) residents undergoing diagnostic SARS-CoV-2 testing and describe the diagnostic accuracy of temperature measurements for predicting test-confirmed SARS-CoV-2 infection. […] Retrospective cohort study evaluating diagnostic accuracy of pre-SARS-CoV-2 testing temperature changes. | 2020-10-09 |
| 33034142 | Prior to the COVID-19 pandemic, laryngoscopy was the mandatory gold standard for the accurate assessment and diagnosis of inducible laryngeal obstruction. […] In response, we have convened a multidisciplinary panel with broad experience in managing this disease and agreed a recommended strategy for presumptive diagnosis in patients who cannot have laryngoscopy performed due to pandemic restrictions. | 2020-10-09 |
| 33034239 | We conducted a retrospective cohort study of all solid-organ transplant recipients admitted with a diagnosis of COVID-19 in our 23-hospital health system over a 1-month period. | 2020-10-09 |
| 33034267 | In light of the ongoing coronavirus disease 2019 pandemic, many health-care settings are now implementing these techniques amid respirator shortages. | 2020-10-09 |
| 33034338 | A wide range of machine learning techniques has been deployed to develop models. | 2020-10-09 |
| 33034577 | During this pandemic period, the need to exclude the possibility of COVID-19 pneumonia in patients with acute dyspnea may cause a delay in the diagnosis and treatment of patients with acutely decompensated HF who have similar symptoms. […] The objective of this report is to draw attention to the differential diagnosis of HF and COVID-19 pneumonia. | 2020-10-09 |
| 33034578 | The patient was admitted to the coronary intensive care unit with the diagnosis of pericardial tamponade. […] Pericardial effusion and pericardial tamponade should be considered in the differential diagnosis of patients with COVID-19 exhibiting dyspnea or worsening of dyspnea. […] The patient was admitted to the coronary intensive care unit (CICU) with the diagnosis of pericardial tamponade. […] Patients with COVID-19 infection who develops or have worsening dyspnea, pericardial effusion and pericardial tamponade should be considered in differential diagnosis. | 2020-10-09 |
| 33035150 | Innovation and Conclusion: As this virus continues to spread silently, mainly through asymptomatic carriers, an accurate and rapid identification of these cutaneous manifestations may be vital to early diagnosis and lead to possible better prognosis in COVID-19 patients. | 2020-10-09 |
| 33035176 | While the trigger for the development of each of these templates was the COVID-19 pandemic, the templates represented a variety of types of data sets - symptom screening; infection report; clinical decision support for diagnosis and treatment; and secondary use/research. | 2020-10-09 |
| 33035211 | All positive specimens were collected within 3 days after diagnosis, and 10 (10/42, 23.8%) were found in toilet (5 on toilet bowl, 4 on sink/faucet/shower, 1 on floor drain), 4 (4/21, 19.0%) in anteroom (2 on water dispenser/cup/bottle, 1 on chair/table, 1 on TV remote), 1 (1/8, 12.5%) in kitchen (1 on dining-table), 1 (1/18, 5.6%) in bedroom (1 on bed/sheet pillow/bedside table), 1 (1/5, 20.0%) in car (1 on steering wheel/seat/handlebar) and 3 (3/20, 21.4%) on door knobs. | 2020-10-09 |
| 33035216 | After a COVID-19 diagnosis, vulnerable populations face considerable logistical and financial challenges to isolate and quarantine. | 2020-10-09 |
| 33035306 | SARS-CoV-2 IGRA may serve as a useful diagnostic tool in managing the COVID-19 pandemic. | 2020-10-09 |
| 33035434 | In the circulation, these membranous vesicles are mainly derived from blood or vascular cells, and they carry cargos with distinct molecular signatures reflecting the origin and activation state of parent cells that produce them, thus providing a powerful tool for diagnosis and prognosis of pathological conditions. […] In this review, we provide a brief summary of the current knowledge on EV biology and advanced techniques in EV isolation and characterization. […] We conclude with a translational perspective on the diagnostic and therapeutic potential of EVs in vascular injury or infectious diseases, such as COVID-19. | 2020-10-09 |
| 33035991 | Patients with cancer and a laboratory-confirmed diagnosis of COVID-19 were prospectively identified using provincial registries and hospital databases between March 3rd and May 23rd, 2020 in the provinces of Quebec and British Columbia in Canada. […] The exposure of interest was incidence of hospital-acquired infection defined by diagnosis of SARS-CoV-2 ≥ 5 days after hospital admission for COVID-unrelated cause. […] One hundred and six patients (42.1%) received active anticancer treatment in the last 3 months before COVID-19 diagnosis. […] Forty-seven (19.1%) had a diagnosis of hospital-acquired COVID-19. | 2020-10-09 |
| 33036445 | A COVID-19 diagnosis based on clinical parameters only does not appear possible. | 2020-10-10 |
| 33036570 | Structured diagnostic algorithms and clinical management are suggested to improve COVID-19/HIV/TB or COVID-19/TB co-infections outcomes. | 2020-10-10 |
| 33036662 | Confirmed SARS-CoV-2 diagnosis (Positive polymerase chain reaction (PCR)) 5. | 2020-10-10 |
| 33036676 | One hundred and sixty-nine patients with the diagnosis of Covid-19 were retrospectively reviewed. | 2020-10-10 |
| 33036761 | We describe the case of a 24-year-old pregnant woman with no history of note who was admitted with a diagnosis of bilateral pneumonia caused by the new coronavirus. […] After extubation, she presented altered mental state that required a differential diagnosis of encephalitis/meningitis secondary to SARS-CoV-2. […] PRES is associated with certain clinical (headache, altered mental state, visual disturbances and convulsions) and radiological (reversible changes in white substance mainly affecting the parietal, temporal, and occipital lobes) characteristics suggestive of vasogenic oedema In pregnant SARS-CoV-2 patients, the differential diagnosis of hypertension and altered mental state is often extremely complicated because complementary tests can be normal and there is no immediate sign of peripartum hypertension. […] SARS-CoV-2 genome sequencing in spinal fluid could have provided a definitive diagnosis, but the treatment would not have differed. | 2020-10-10 |
| 33036896 | The Accreditation Council for Graduate Medical Education (ACGME) Core Competencies for Diagnostic Radiology helped guide division leadership in restructuring and reframing breast imaging education during this time of drastic change and persistent uncertainty. | 2020-10-10 |
| 33037070 | Our objective was to compare testing for, diagnosis of and death after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection across 3 settings (residents of long-term care homes, people living in shelters and the rest of the population). […] After adjusting for age and sex, residents of long-term care homes were 2.4 (95% confidence interval [CI] 2.2-2.7) times more likely to test positive, and those who received a diagnosis of COVID-19 were 1.4-fold (95% CI 1.1-1.8) more likely to die than the rest of the population. | 2020-10-10 |
| 33037212 | In such a difficult multi-class diagnosis task, our deep convolutional neural network-based system is able to achieve an area under the receiver operating characteristic curve (AUC) of 97.81% for multi-way classification on test cohort of 3,199 scans, AUC of 92.99% and 93.25% on two publicly available datasets, CC-CCII and MosMedData respectively. […] Diagnosis performance of chest x-ray (CXR) is compared to that of CT. | 2020-10-10 |
| 33037291 | The use of imaging data has been reported to be useful for rapid diagnosis of COVID-19. […] However, current investigation of pretrained convolutional neural networks (CNNs) for COVID-19 diagnosis using CT data is limited. | 2020-10-10 |
| 33038252 | These data showed that both techniques are equally sensitive in detecting SARS-CoV-2 providing additional value of DETECTR to the currently used qRT-PCR platforms. […] As there is no need for specialized equipment, DETECTR could be rapidly implemented as a complementary technically independent approach to qRT-PCR thereby increasing the testing capacity of medical microbiological laboratories and relieving the existent PCR-platforms for routine non-SARS-CoV-2 diagnostic testing. | 2020-10-10 |
| 33038410 | From March 7th to April 28th, forty consecutive patients with known cardiac disease (chronic coronary artery disease, n=38; atrial fibrillation, n = 7; valvular disease, n = 13) referred to our emergency department for symptoms of suspected COVID-19, laboratory diagnosis of COVID-19 and typical signs of viral pneumonia at chest CT were enrolled in the study. | 2020-10-10 |
| 33038433 | The rapid release of the sequence of the virus has allowed the development of diagnostic tools (e.g., RT-PCR). […] The aim of this review is to provide insights on the discovery of SARS-CoV-2, its virology, the diagnostic tools, and the ongoing drug discovery effort. | 2020-10-10 |
| 33038435 | Opportunity exists to decrease healthcare-related exposure to SARS-CoV-2, preserve infection control resources and increase care capacity by reducing the time to diagnosis of COVID-19. […] In comparison to standard-platform testing, rapid testing was associated with a 65.6% reduction (12.6 hours) in median time to removal from isolation cohort for patients with negative diagnostic results. | 2020-10-10 |
| 33038445 | However, the additional contribution of the second PCR test to the diagnosis is unknown. […] In this study, we aimed to investigate the contribution of second SARS-CoV-2 PCR to diagnosis in patients with a suspicion of COVID-19 whose initial test was negative. […] The strategy of using the second nasopharyngeal PCR test to confirm or exclude the diagnosis seems to cause the loss of labor and time, and is costly, because its additional contribution to the first test is very low. | 2020-10-10 |
| 33038570 | In resource-poor settings where molecular testing results suffered from delays or were altogether unavailable, the use of diagnostic imaging such as a chest x-ray could serve as a quick guide in the assessment and management of these patients especially if the imaging results suggest COVID-19 infection. | 2020-10-10 |
| 33038619 | CT chest had 57% sensitivity (CI 18.41% to 90.1%) and 100% specificity (CI 92% to 100%) in COVID-19 diagnosis. | 2020-10-10 |
| 33038789 | Patterns of stability/change did not differ according to diagnostic category. | 2020-10-10 |
| 33039094 | A comparison of the clinical performance of the Elecsys Anti-SARS-CoV-2, Liaison SARS-CoV-2 S1/S2 IgG, Access SARS-CoV-2 IgG and Vitros Immunodiagnostic Products Anti-SARS-CoV-2 IgG immunoassays for the diagnosis of COVID-19 infection was performed. | 2020-10-11 |
| 33039095 | However, their poor sensitivity and delayed antibody detection make them unsuitable as a diagnostic or screening tool alone. | 2020-10-11 |
| 33039097 | We discuss evidence-based recommendations to mitigate the risk of viral transmission through novel techniques and device implementation as well as increasing conservative management of certain pathologies. | 2020-10-11 |
| 33039215 | Despite relatively low local prevalence of COVID-19, we report decreases in ED volume for some medical diagnosis categories. | 2020-10-11 |
| 33039218 | Better understanding and awareness of these symptoms can lead to more efficient diagnosis, rapid treatment, isolation, and decreased spread of the disease. | 2020-10-11 |
| 33039221 | Cumulative mortality was showed in Kaplan-Meier survival curves after the surgery in the 2020 group was significantly different higher than the 2019 group during the 28 days.The diagnosis and treatment process of STEMI patients during an epidemic should be optimized to improve their prognosis. | 2020-10-11 |
| 33039225 | Resuscitation techniques in COVID-19 era at the beach have added complexities for the correct use of PPE. | 2020-10-11 |
| 33039230 | In this era of pandemic, it is very important for the physicians to be aware of association of GBS with Covid-19, as early diagnosis and treatment of this complication could have gratifying results. | 2020-10-11 |
| 33039307 | Factors considered included: rota and shift pattern changes to implement depth and resilience to sudden fluctuations in staffing levels; a preparatory phase for focussed upskilling and relevant training packages to be delivered; managing the COVID-19 ward cover and ITU deployment; adjustments to our front of house and elective specialty-specific service, including developing alternative and streamlined patient pathways; mitigating the effects on plastic surgical training during the pandemic; the importance of communications for patient care and physician wellbeing; and leadership techniques and styles we considered important. | 2020-10-11 |
| 33039612 | Reverse transcription-polymerase chain reaction remains the gold-standard for SARS-CoV-2 diagnosis, but several practical issues limit the test use. […] To access the performance of twelve serological tests for COVID-19 diagnosis. | 2020-10-11 |
| 33039765 | Our clinical and treatment approach with differential diagnosis are discussed in this hitherto unreported obstetric emergency with COVID-19. | 2020-10-11 |
| 33039966 | Lymphocytes, eosinophils, CD3+ T cells, CD4+ T cells, IL-6 and IL-10 all had great diagnostic efficacy (AUC, 0.905-0.975) for COVID-19. | 2020-10-11 |
| 33040020 | Consecutive adult hospitalised patients with a virologically confirmed diagnosis of COVID-19. | 2020-10-11 |
| 33040064 | The impact of COVID-19 for gastrointestinal emergencies is addressed together with the implications for the conduct of endoscopic and other interventional and diagnostic procedures. | 2020-10-11 |
| 33040241 | This has implications for cardiac monitoring, chemotherapy administration, and the diagnosis and treatment of cardiovascular disease during COVID-19. | 2020-10-11 |
| 33040337 | Different from strong and persistent N specific antibodies, S1 specific IgM responses, which evolved in asymptomatic individuals as early as the seventh day after exposure, peaked on days from 17d to 25d, and then disappeared in two months, might be used as an early diagnostic biomarker. […] Our findings might have important implications for the definition of asymptomatic COVID-19 infections, diagnosis, serological survey, public health and immunization strategies. | 2020-10-11 |
| 33040344 | Our inclusion criteria for Study Subjects were: (i) clear clinical diagnosis, (ii) dermoscopic confirmation, (iii) differential diagnoses excluded, (iv) eosinophilia, (v) protective gear worn during sanitation services, (vi) temporal correlation, (vii) distributional correlation, (viii) physician-assessed association, and (ix) patient-assessed association. | 2020-10-11 |
| 33040422 | As compared to pre-restriction, the odds of retrieval for the restriction and post-restriction period differed across time between the major diagnostic groups. | 2020-10-11 |
| 33040430 | Transplantation in potential candidates who have recently recovered from COVID-19 is a challenge with uncertainties regarding the diagnosis, multi-organ systemic involvement, prolonged viral shedding in immunocompromised patients, and optimal immunosuppression. […] A 42 year male with alcoholic hepatitis underwent a successful deceased donor liver transplantation 71 days after the initial diagnosis of COVID-19. | 2020-10-11 |
| 33040480 | We undertook a retrospective analysis of all patients admitted with a pre-existing diagnosis of HF between 1 March and 6 May 2020 to our unit. | 2020-10-11 |
| 33040775 | Various machine learning techniques: Decision Trees, Linear Regression and Random Forest have been applied to correlate air pollutants and COVID-19 fatalities in Delhi. | 2020-10-12 |
| 33041077 | In this single center retrospective observational study, medical records of all kidney transplant recipients at the UCLA Medical Center were reviewed for a diagnosis of COVID-19 by polymerase chain reaction, followed by chart review to determine kidney transplant characteristics and clinical course. […] Recipients had been transplanted for a median of 47 months before diagnosis. | 2020-10-12 |
| 33041213 | However, achieving accurate testing necessitates proper nasopharyngeal swab techniques. […] All participants surveyed felt that the 3D printed models were useful and beneficial in the training of nasopharyngeal swab techniques. | 2020-10-12 |
| 33041346 | In this installment of Work/Life Balance, we elaborate on how mindfulness may help employees deal with these work issues, explain how mindfulness can be cultivated, and provide a list of mindfulness techniques. | 2020-10-12 |
| 33041350 | By virtual screening, molecular docking and molecular dynamics techniques, we have established a strong inhibitory possibility of choline for SARS 3CLpro protease which may provide a lead for prenatal COVID-19 treatment. | 2020-10-12 |
| 33041409 | Computer Tomography (CT) imaging of the chest is a valid diagnosis tool to detect COVID-19 promptly and to control the spread of the disease. […] The obtained gain, though of low entity, can be really important in medical diagnosis and, in particular, for Covid-19 scenario. | 2020-10-12 |
| 33041505 | Although high-resolution manometry (HRM) is an essential device for diagnosis of functional gastrointestinal disorders, it contains risks of droplet infection, contact infection and aerosol-borne infection. | 2020-10-12 |
| 33041533 | Here, we perform an overview on the applications of AI in a variety of fields including diagnosis of the disease via different types of tests and symptoms, monitoring patients, identifying severity of a patient, processing covid-19 related imaging tests, epidemiology, pharmaceutical studies, etc. | 2020-10-12 |
| 33041635 | In this study, Convolutional Neural Network (CNN), one of the deep learning methods, was used which suggested automatic classification of CT images of lungs for early diagnosis of Covid-19 disease. | 2020-10-12 |
| 33041989 | Mean time to performing electrodiagnostic study from onset of neurological symptom was 6 days with standard deviation of 3.25. […] Six patients had demyelinating pattern, three had acute sensory motor axonal neuropathy, and one had acute motor axonal neuropathy on electrodiagnostic studies. | 2020-10-12 |
| 33042210 | Studies are ongoing for the diagnosis and treatment of this disease, which is defined as a pandemic. […] Early diagnosis of this disease is important for human life. […] This process is progressing rapidly with diagnostic studies based on deep learning. […] Therefore, to contribute to this field, a deep learning-based approach that can be used for early diagnosis of the disease is proposed in our study. […] The results obtained by verification with two different metaheuristic algorithms proved that the approach we propose can help experts during COVID-19 diagnostic studies. | 2020-10-12 |
| 33042308 | We exploit supervised machine learning techniques building a model considering a data-set freely available for research purposes of 85 chest X-rays. | 2020-10-12 |
| 33042586 | In this expert opinion, the authors canvas the many challenges in the diagnosis, treatment and delivery of care to patients with congestive heart failure and acute coronary syndromes during the COVID-19 pandemic. | 2020-10-12 |
| 33042602 | MG vs. consumer off the shelf vs. professional grade) on pathologists’ diagnostic performance and (b) discuss the impact of the recent digital pathology device componentization and the coronavirus disease 2019 public emergency on the pixel pathway and display use for remote digital pathology. | 2020-10-12 |
| 33042732 | Cas12a-based systems, which detect specific nucleic acids via collateral cleavage of reporter DNA, display huge potentials for rapid diagnosis of infectious diseases. […] MeCas12a can detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples and distinguish between SARS-CoV-2 and Middle East respiratory syndrome coronavirus (MERS-CoV) RNA in simulated samples, thus offering an attractive alternative to other methods for the diagnosis of infectious diseases including COVID-19 and MERS. | 2020-10-12 |
| 33042803 | We retrospectively analyzed the diagnosis and treatment of six gynecological cancer patients infected with SARS-CoV-2 in Tongji Hospital in Wuhan from January 30 to March 25, 2020. […] Also, due to the influence of cancer treatment history, COVID-19-related atypical symptoms became the first symptom of COVID-19 in some cases, which increased the difficulty of diagnosis. […] Besides, the history of cancer treatment made the diagnosis of COVID-19 difficult, which also affected the treatment of COVID-19. | 2020-10-12 |
| 33042826 | Time from symptoms onset to first positive SARS-CoV-2 PCR was 5.5 days (range 1-17), with 13% of cases needed from a 2nd PCR to confirm diagnosis. | 2020-10-12 |
| 33043063 | A retrospective cohort study consisting of all hospitalizations with a confirmed COVID-19 diagnosis discharged between March 15, 2020 and April 30, 2020 was conducted. | 2020-10-12 |
| 33043106 | The SEIR (Susceptible Exposed Infectious and Recovered) dynamic approach and moving average estimation were used to forecast the daily infected and cumulative cases until 16 June as a base run analysis using STELLA dynamic software and statistical techniques. | 2020-10-12 |
| 33043290 | Early etiological diagnosis plays a critical role in controlling COVID-19 pandemic. […] However, etiological diagnosis has been largely compromised by high “false negative” rates of viral nucleic acid testing, resulting from limited sampling efficiency using conventional oropharyngeal swabs. | 2020-10-12 |
| 33043291 | Based on this pilot study, our multiplexed immunosensor platform may allow for high frequency at-home testing for COVID-19 telemedicine diagnosis and monitoring. | 2020-10-12 |
| 33043311 | This makes the ZSL applicable in many real-world scenarios, from unknown object detection in autonomous vehicles to medical imaging and unforeseen diseases such as COVID-19 Chest X-Ray (CXR) based diagnosis. […] We review over fundamentals and the challenging steps of Zero-Shot Learning, including state-of-the-art categories of solutions, as well as our recommended solution, motivations behind each approach, their advantages over each category to guide both clinicians and AI researchers to proceed with the best techniques and practices based on their applications. […] We mainly focus on two applications in the current modern yet challenging era: coping with an early and fast diagnosis of COVID-19 cases, and also encouraging the readers to develop other similar AI-based automated detection / recognition systems using ZSL. | 2020-10-12 |
| 33043363 | We performed a systematic review and meta-analysis to investigate its diagnostic accuracy for the detection of fever. […] Forest plots and Hierarchical Summary Receiver Operating Characteristics curves were used to describe the pooled summary estimates of sensitivity, specificity and diagnostic odds ratio. […] Thermal screening has reasonable diagnostic accuracy in the detection of fever, although it may vary with changes in subject characteristics, setting, index test, and the reference standard used. | 2020-10-12 |
| 33043603 | Detection of SARS-CoV-2 viral RNA by RT-PCR assays is the primary diagnostic test for COVID-19. | 2020-10-12 |
| 33043651 | Between 20 February and 28 March 2020, 10 patients (7 males) who were under warfarin therapy for prosthetic heart valves were hospitalized after a diagnosis of COVID-19 in Tehran Heart Center, Tehran, Iran. | 2020-10-12 |
| 33043740 | The pharmaceutical industries are developing clinical diagnostic kits, medicines, and vaccines. […] They target different approaches, including repurposing the already approved diagnosis and treatment options for similar CoVs. | 2020-10-12 |
| 33043818 | Clinical sensitivity increased between early (<14 days post symptom onset or post diagnosis, dpos/dpd) and late sera (>14 dpos/dpd) from 75.0 (64.7-83.2) to 83.1 (76.5-88.1). | 2020-10-12 |
| 33043852 | Age ranged from 56 to 99 years (mean = 82) and 148 were female (67%). 119 patients had a positive swab for SARS-CoV-2 within the first 14 days of admission, only 32% of these patients presented with primarily a respiratory type illness. 103 patients (46%) tested positive after 14 days of admission - this was felt to represent likely nosocomial infection. 95 patients (43%) died by day 30 after diagnosis. | 2020-10-12 |
| 33043879 | These efforts were based on (1) phone diagnosis, dispatch, and transport, and (2) border management checkpoints. | 2020-10-12 |
| 33044019 | Among patients with a diagnosis of COVID-19 in our propensity matched cohort, the mean ages±SD were 62.3±15.9 years (53.7% male) and 61.9±16.0 years (53.0% male) in the HCQ and no-HCQ groups, respectively. | 2020-10-12 |
| 33044091 | The main objective of this study is to determine the knowledge level and its association with sources of information towards COVID-19 and its prevention techniques in the Gedeo Zone of Southern Ethiopia. […] There are 10 knowledge questions regarding COVID-19 and its prevention techniques. […] Regarding knowledge level, 60.5% have good knowledge about COVID-19 and its prevention techniques. | 2020-10-12 |
| 33044173 | The diagnostic accuracy of SCT and QCT in the differentiation of clinically limited (mild, common) and extensive (severe, critical) disease was investigated using ROC analysis. […] Seventy-six patients with a diagnosis of COVID-19 were included. | 2020-10-12 |
| 33044601 | In the fight against epidemic infectious diseases in the past 2,000 years, Chinese medicine (CM) has gradually developed a complete response system including diagnosis and treatment. […] The improvement of the diagnosis and treatment system of CM based on scientific concepts and methods and the organic combination of both treatment methods of modern medicine and CM will provide the best solution for humans to defeat epidemic infectious diseases. | 2020-10-12 |
| 33044938 | Early and accurate diagnosis of Coronavirus disease (COVID-19) is essential for patient isolation and contact tracing so that the spread of infection can be limited. | 2020-10-12 |
| 33045049 | Most malaria-endemic countries run well-entrenched malaria control programs via their established frameworks for diagnosis, case management, treatment and overall surveillance. | 2020-10-12 |
| 33045106 | Rapid diagnosis, appropriate care and monitoring seem however to improve prognosis. | 2020-10-12 |
| 33045255 | Cases of even symptomatically mild COVID-19 infection were accompanied by AKI and/or heavy proteinuria that prompted a diagnostic kidney biopsy. | 2020-10-12 |
| 33045270 | The aim of this report was to contribute to the practice of endodontics by proposing a general protocol for the management of emergencies showing the rationale for remote diagnosis, clinical procedures and use of personal protective equipment and barriers at the dental office, during the COVID-19 outbreak. | 2020-10-12 |
| 33045283 | Currently, the diagnosis is based on molecular real time RT-PCR techniques, although their implementation is being threatened due to the extraordinary demand for supplies worldwide. […] According to the preliminary results obtained, accuracy = 67.66 %, sensitivity = 61.76 %, specificity = 71.72 %, and although these parameters still need to be improved to be used as a screening technique, mass spectrometry-based methods coupled with multivariate analysis showed that it is an interesting tool that deserves to be explored as a complementary diagnostic approach due to the low cost and fast performance. | 2020-10-12 |
| 33045362 | There is no effective treatment of the disease, hence, scaling up testing for rapid diagnosis of SARS-CoV-2 infected patients and quarantine them from healthy individuals is one the best strategies to curb the pandemic. […] Establishing globally accepted easy-to-access diagnostic tests is extremely important to understanding the epidemiology of the present pandemic. […] CRISPR based novel techniques, when merge with isothermal and allied technologies, promises to provide sensitive and rapid detection of SARS-CoV-2 nucleic acids. […] Here, we discuss and present compilation of state-of-the-art detection techniques for COVID-19 using CRISPR technology which has tremendous potential to transform diagnostics and epidemiology. | 2020-10-12 |
| 33045370 | To examine whether specific T-cell-responses to SARS-CoV-2 peptides can be detected in COVID-19 using a whole-blood experimental setting, which may be further explored as potential diagnostic tool. […] This experimental approach may be useful for developing new T-cell based diagnostic tests for disease and vaccine settings. | 2020-10-12 |
| 33045450 | Because of the rapid negative diagnosis for COVID-19 using the LAMP method, eCAS could be performed following standard procedures, along with infectious defense, without delay. […] During the COVID-19 pandemic, the LAMP assay for COVID-19 detection might be a suitable diagnostic strategy preceding stroke treatment because of the rapid turnaround time. | 2020-10-12 |
| 33045467 | Real-time reverse transcription-PCR (rRT-PCR) has been the most effective and widely implemented diagnostic technology since the beginning of the COVID-19 pandemic. […] However, fuzzy rRT-PCR readouts with high Ct values are frequently encountered, resulting in uncertainty in diagnosis. […] SENA increases both the sensitivity and the specificity of rRT-PCR, solving the uncertainty problem in COVID-19 diagnosis and thus providing a simple and low-cost companion diagnosis for combating the pandemic. | 2020-10-12 |
| 33045476 | The chest computed tomography (CT) features of coronavirus disease 2019 (COVID-19) and Streptococcus pneumoniae pneumonia (S. pneumoniae pneumonia) were compared to provide further evidence for the differential imaging diagnosis of patients with these two types of pneumonia. | 2020-10-12 |
| 33045477 | The pulmonary imaging (chest computed tomography and Digital radiography) are indispensable for definitive diagnosis and reexamination. | 2020-10-12 |
| 33045494 | Factors associated with major severity of symptoms were: marital status, previous diagnosis of mood disorders, switching/starting Disease-Modifying Therapies in the last 12 months, and a higher level of disability measured with Expanded Disability Status Scale (for all, p<.05> | 2020-10-12 | </.05>
| 33045499 | The diagnosis of coronavirus disease-19 (COVID-19) relies on the detection of severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) RNA by real-time reverse-transcription polymerase chain reaction in respiratory samples. […] Rapid increase in the COVID-19 cases across the world requires fast and efficient testing as testing capacity is a bottleneck in diagnosis. | 2020-10-12 |
| 33045513 | This study employed an ensemble of measurement and modelling techniques to investigate changes in air quality, atmospheric composition and boundary layer reactivity in the South East of the UK post-lockdown. […] The techniques employed included in-situ gas- and particle-phase monitoring within central and local authority air quality monitoring networks, remote sensing by long path Differential Optical Absorption Spectroscopy and Sentinel-5P’s TROPOMI, and detailed 0-D chemical box modelling. | 2020-10-12 |
| 33045571 | Thus, there is an urgent need to identify early diagnostic and prognostic biomarkers to determine the risk of developing serious illness. | 2020-10-12 |
| 33045980 | Relaxation techniques have been demonstrated to positively affect immune functions, glycemic control, and stress levels. […] The search included clinical trials and systematic and literature reviews on the effects of relaxation techniques on immune functions, glycemic control, and stress levels. […] This review found that relaxation techniques produce short-term effects on decreasing stress levels through an autonomic regulation, controlling glycemic control through decreasing hyperglycemia, and increasing immune functions through increasing immune cells and immunoglobins A. […] This review summarizes the important role of performing regular relaxation techniques for COVID-19 patients with DM. […] Relaxation techniques benefit diabetic patients with COVID-19 through decreasing stress levels, better controlling of glycemic control, and increasing immune functions. | 2020-10-13 |
| 33046310 | Unenhanced chest computed tomography (CT) can assist in the diagnosis and classification of coronavirus disease 2019 (COVID-19), complementing to the reverse-transcription polymerase chain reaction (RT-PCR) tests; the performance of which has yet to be validated in emergency department (ED) setting. […] The study sought to evaluate the diagnostic performance of chest CT in the diagnosis and management of COVID-19 in ED. […] Their final diagnosis was considered as reference. […] Chest CT showed a sensitivity of 84.6%, a specificity of 80.0% and a diagnostic accuracy of 81.9% in suggesting COVID-19 with RT-PCR as reference. […] Concurrently, corresponding values of 89.4%, 84.3% and 86.5% were retrieved with the adjudication committee diagnosis as reference. | 2020-10-13 |
| 33046850 | In this Review, we summarize and evaluate the available evidence on the pathogenesis, diagnosis and treatment of myocarditis and inflammatory cardiomyopathy, with a special focus on virus-induced and virus-associated myocarditis. | 2020-10-13 |
| 33047077 | A nucleic acid real-time quantitative polymerase chain reaction (RQ-PCR) test of nasopharyngeal samples is the standard method for the diagnosis of an active SARS-CoV-2 infection. […] However, many limitations of the RQ-PCR tests make them unsuitable for the simple and rapid diagnosis of COVID-19 patients. | 2020-10-13 |
| 33047081 | The arms were stratified based on the presence of a secondary discharge diagnosis of obesity. | 2020-10-13 |
| 33047223 | The electrodiagnostic test showed decremental response over more than 10% on repetitive nerve stimulation test of orbicularis oculi. | 2020-10-13 |
| 33047493 | Among them, three showed very low numbers of SARS-CoV-2-reactive T cells whereas no T cell response was detected in the other three, potentially ruling out COVID-19 diagnosis. […] These results suggest that during COVID-19, monitoring both T cell and serological immunity might be helpful for the differential diagnosis of COVID-19 but are also needed to evaluate a potential role of antiviral T cells in the development of severe forms of the disease. | 2020-10-13 |
| 33047791 | Competency domains were divided into ‘knowledge’, ‘skills’, and ‘attitudes’ and were classified into four categories: etiology, assessment and diagnosis, management, and prognosis. […] Fifty-two essential competencies were identified; 7 competencies on etiology, 7 related to assessment and diagnosis, 34 related to management, and 4 related to prognosis. | 2020-10-13 |
| 33048282 | To quantify the clinical utility of identifying OD in the diagnosis of COVID-19 and determine an estimate of the frequency of OD amongst these patients. […] Patients with reported OD were more likely to test positive for COVID-19 (diagnostic odds ratio 11.5 [8.01-16.5], sensitivity 0.48 (0.40 to 0.56), specificity 0.93 (0.90 to 0.96), positive likelihood ratio 6.10 (4.47-8.32) and negative likelihood ratio 0.58 (0.52-0.64)). | 2020-10-13 |
| 33048424 | Here, we prospectively monitored the dynamic changes of SARS-CoV-2 RNA viral loads in serial nasopharyngeal swab, saliva, and respiratory specimens collected from kidney transplant recipients (KTR) hospitalized with a confirmed diagnosis of Covid-19. | 2020-10-13 |
| 33048773 | To counter the outbreak of COVID-19, the accurate diagnosis of suspected cases plays a crucial role in timely quarantine, medical treatment, and preventing the spread of the pandemic. | 2020-10-13 |
| 33048778 | Further, we explore the epidemiology, symptoms of the disease, describe the reverse transcriptase-polymerase chain reaction (RT-PCR) that establishes the diagnosis of the disease and also review its unique diagnostic features in the chest CT-Scan. | 2020-10-13 |
| 33048785 | Their chest radiograph was normal or non-diagnostic. | 2020-10-13 |
| 33048824 | Therefore, the selection of patients for diagnosis and treatment is essential in this situation. | 2020-10-13 |
| 33048890 | Conclusion and RelevanceNew diagnosis of thrombosis during COVID-19 hospitalization, a measure of COVID-19 disease severity, was the factor most associated with dependence in ADLs at discharge. | 2020-10-13 |
| 33049069 | The importance of study of mutations is related to the possible virulence and diagnosis of SARS-CoV-2. […] To identify circulating mutations present in SARS-CoV-2 genomic sequences in Mexico, Belize and Guatemala to find out if the same strain spread to the south, and analyze the specificity of the primers used for diagnosis in these samples. 23 complete SARS-CoV-2 genomic sequences, available in the GISAID database from May 8 to September 11, 2020 were analyzed and aligned versus the genomic sequence reported in Wuhan, China (NC_045512.2), using Clustal Omega. […] Finally, the sequences were aligned versus primers used in the diagnosis of COVID-19. 187 distinct variants were identified, of which 102 are missense, 66 synonymous and 19 non-coding. […] The genomic sequences of SARS-CoV-2 in Mexico, Belize and Guatemala present similar mutations related to a virulent strain of greater infectivity, which could mean a greater capacity for inclusion in the host genome and be related to an increased spread of the virus in these countries, further, its diagnosis would be affected. | 2020-10-13 |
| 33049464 | Five hundred and seventy-five patients with a mean age (years±SD) of 68±16 were admitted from December 1st, 2019 to June 30th, 2020, with a clinical diagnosis of acute ischemic stroke. | 2020-10-13 |
| 33049547 | Analyses were adjusted for sex, age group, highest academic achievement, working status during quarantine, skin color, previous diagnosis of depression, and adherence to quarantine. | 2020-10-13 |
| 33049594 | Therefore, pathophysiological knowledge about COVID-19 is imperative for better planning of preventive measures, diagnosis, and therapeutics of the disease. […] Based on previous studies, this work proposes new hypothesis related to the role of the renin-angiotensin system on the pathophysiology of COVID-19, and its purpose is to enrich the discussion and to offer alternative ways for experimental and clinical studies aiming at the formulation of new diagnosis and/or treatment methods. | 2020-10-13 |
| 33049753 | The patients recorded their subjective symptoms before and during infection as well as 4 weeks after the diagnosis. | 2020-10-13 |
| 33050240 | Cancer cells also change genetically, and current therapeutic techniques may be (or may become) ineffective in many cases. […] Viral infections spread and develop much more quickly than does the corresponding research needed to prevent and combat these infections; the present and most relevant outbreak of SARS-CoV-2, which originated in Wuhan, China, illustrates the critical and immediate need to improve drug design and development techniques. […] The basic concepts, theories, and applications of the most commonly used NMR techniques are presented. | 2020-10-14 |
| 33050499 | In this systematic review, we investigate the epidemiology, pathogenesis, risk factors, clinical manifestations, diagnosis and treatment of COVID-19-associated pulmonary aspergillosis (CAPA). […] A thorough, multi-faceted diagnostic work-up and early initiation of a mold-active triazole may be lifesaving. | 2020-10-14 |
| 33050601 | Here, we review the current status and future perspectives of biomedical science in the context of COVID-19, including nanotechnology, prevention through vaccine engineering, diagnostic, monitoring, and therapy. | 2020-10-14 |
| 33050880 | We aimed to reveal diagnostic clues of headache for COVID-19 infection and to investigate the course of primary headaches during the pandemic. […] Among them, 262 participants had COVID-19 diagnosis and 126 (48.1%) were male. | 2020-10-14 |
| 33050892 | The clinical characteristics, reverse transcriptase-polymerase chain reaction (RT-PCR) results from throat swab specimens and the results of serological COVID-19 rapid diagnostic test (RDT) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were retrospectively reviewed for a total of 758 recovered patients who were previously hospitalized in 17 hospitals and quarantined at 32 rehabilitation stations in Wuhan, China. | 2020-10-14 |
| 33050924 | Inclusion criteria are: 65-year-old or more; Positive test for SARS-CoV-2 on a nasopharyngeal swab; Symptoms onset within 3 days before diagnosis; No hospitalisation criteria; Signed informed consent; Health insurance. | 2020-10-14 |
| 33051005 | This article describes a proposed strategy for diagnosis and treatment of diabetic foot ulcers, based on experiences with infection and control strategies during the COVID-19 pandemic in China. | 2020-10-14 |
| 33051223 | Thematic analysis was conducted applying constant comparison techniques. | 2020-10-14 |
| 33051386 | In daily clinical practice, it is important to consider COVID-19 as a differential diagnosis, because these symptoms may be the first warning signs. | 2020-10-14 |
| 33051732 | For this reason, there is an emphasis on evaluating diagnostic tools for screening. […] Chest CT scans are emerging as a useful tool in the diagnostic process of viral pneumonia cases associated with COVID-19. […] • Avoid chest CT as a sole diagnostic approach for COVID-19 infection. | 2020-10-14 |
| 33051893 | Two patients underwent surgery with concomitant diagnosis of coronavirus disease. | 2020-10-14 |
| 33052154 | Considerable progress has been attained in designing FET devices, especially for biomedical diagnosis and cell-based assays in the past few decades. | 2020-10-14 |
| 33052193 | By employing the empirical Markov switching regression approach and the compliments of cointegration techniques, the study establishes a two-state (stable and distressing) financial stress situation resulting from the effects of COVID-19 daily deaths, COVID-19 daily recovery, and the USA’ economic policy uncertainty. | 2020-10-14 |
| 33052197 | The automation of clinical de-identification through deep learning techniques has proven to be less effective for languages other than English due to the scarcity of data sets. | 2020-10-14 |
| 33052198 | In most cases of COVID-19 it is too early for the diagnosis of a post-COVID syndrome. | 2020-10-14 |
| 33052259 | Forty young people aged 12 to 18 years who meet DSM-5 diagnostic criteria for AN, and live in a rural or regional setting, will along with their family be recruited to the study. | 2020-10-14 |
| 33052265 | These GGOs present a wide differential that is narrowed down through diagnostic testing, deliberation of past medical history as well as medication use, and social history. | 2020-10-14 |
| 33052300 | Six months from the diagnosis, after virus eradication, patient underwent breast surgery. | 2020-10-14 |
| 33052573 | Therefore, in the perspective of COVID-19 pandemic, clinicians and healthcare workers should be aware of a wide spectrum of neurological manifestations associated with COVID-19 along with their signs and symptoms for initial diagnosis and isolation of the patients. | 2020-10-14 |
| 33052593 | We queried the database for data on site of the tumor, diagnosis, stage, tumor board decisions and planning, surgical procedures, adjuvant treatment, and follow-up details. | 2020-10-14 |
| 33052811 | We compared patients with more than one COVID-19 test for diagnostic accuracy against the gold standard of chart review. | 2020-10-14 |
| 33052813 | We measured LUS diagnostic performance using computed tomography as the gold standard. | 2020-10-14 |
| 33052958 | We derived the epidemic growth rates (r) and the corresponding reproductive numbers (R) from the epidemic curve of these 1,311 individuals with laboratory-confirmed diagnosis of COVID-19 using their date of test collection as a proxy for symptoms onset. | 2020-10-14 |
| 33052962 | The aerosol filtration characteristics were also studied after sterilisation by different techniques such as heat with 50% humidity (thermal treatment), ethylene oxide (ETO), steam and radiation dose of 30kGy. | 2020-10-14 |
| 33053023 | Data from patients older than 18 years who were admitted to the intensive care unit for mechanical ventilation for acute respiratory failure with a positive diagnosis of COVID-19 were included. | 2020-10-14 |
| 33053061 | This initiative aims to provide information on adherence to preventive measures (social distancing, wearing masks, and handwashing/hygiene); reasons for leaving the house, when that was the case; difficulties obtaining medications, medical diagnosis of COVID-19, and receipt of confirmatory results; use of health-care services (recent care-seeking, care-seeking location, care receipt, among other aspects); and mental health (sleep, depression, and loneliness). | 2020-10-14 |
| 33053426 | A total of 227 (27.3%) patients exhibited LBA and 32 (3.9%) patients were categorized as having LI based on the diagnostic criteria. | 2020-10-14 |
| 33053493 | Diagnostic tests for SARS-COV-2 infection commonly use nasopharyngeal swabs (NPS). […] Moreover, the diagnostic sensitivity and specificity of RT-PCR for the diagnosis of COVID-19 in saliva were 83.43 % (95 % CI: 79.07-87.20) and 96.71 % (95 % CI: 94.85-98.04 %), respectively. | 2020-10-14 |
| 33053582 | However, the number of daily infection cases, hospitalization rate, lag time from onset to diagnosis date and their associations with measures introduced to slow down the spread of COVID-19 have not been fully explored. […] The overall and weekly hospitalization rate and lag time from onset to diagnosis date were calculated. […] The overall hospitalization rate was 45.9% (95% CI 44.7 to 47.1%) and the mean lag time from onset to diagnosis was 11.1±7.4 d. | 2020-10-14 |
| 33053948 | Most of the patients (80 [85.1%]) had COVID-19 symptoms at the time of stroke with a median interval of 10 days to stroke from the diagnosis of COVID-19. […] Three-fourths (86 [74.8%]) of the patients were critically ill which frequently delayed the diagnosis of stroke. | 2020-10-15 |
| 33054603 | The intervention group included a convenience sample of 192 patients who were evaluated in the ED, monitored in the observation unit, or admitted to the hospital with a diagnosis of mild-to-moderate COVID-19 infection. […] Their outcomes were compared to a matched comparison group of 593 patients who were admitted with the same COVID-19-related diagnosis and severity. | 2020-10-15 |
| 33054697 | In the internal validation cohort, the area under the curve of receiver operating characteristics (AUC) was 0.96 [95% confidence interval (CI): 0.89-0.99] for the diagnosis of moderate to high probability of cases among all the suspected patients. […] In the isolation ward, the AUC was 0.94 (95% CI: 0.83-0.99) for the diagnosis of confirmed and probable cases. | 2020-10-15 |
| 33054802 | This study was to investigate the epidemic, clinical, and imaging features of pediatric COVID-19 pneumonia for early diagnosis and treatment. | 2020-10-15 |
| 33054805 | A 65-year-old Caucasian male patient presented to the emergency department with a 2-day history of dyspnea on exertion after his wife’s recent diagnosis of COVID-19. […] It is imperative for health care providers to be mindful of this unique association to make necessary diagnostic evaluations and provide appropriate treatment for the patients. | 2020-10-15 |
| 33057203 | During the early phase of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. […] In this Review, we summarize the crucial role of diagnostic tests during the first global wave of COVID-19. […] Continuous global improvement in diagnostic test preparedness is essential for more rapid detection of patients, possibly at the point of care, and for optimized prevention and treatment, in both industrialized countries and low-resource settings. | 2020-10-15 |
| 33057660 | These events have resulted in a substantial, immediate-term decrease in accrual to both diagnostic and therapeutic cancer investigations as well as substantive alterations in patterns of oncologic care. | 2020-10-15 |
| 33057894 | Bibliographic databases were searched to identify all studies documenting, in adult patients with a confirmed diagnosis of coronavirus disease 2019 (COVID-19): (1) the presence of SARS-CoV-2 ribonucleic acid in the feces; (2) the presence of SARS-CoV-2 ribonucleic acid in the intestinal cells; (3) live SARS-CoV-2 in the feces. | 2020-10-15 |
| 33058134 | Anumber of the patients (9.5%) developed skin lesions at the time of diagnosis of Covid-19 or at the onset of Covid-19 respiratory symptoms while 75.1% developed the lesions after the onset of Covid-19 respiratory symptoms or after laboratory diagnosis of the disease had been made. | 2020-10-15 |
| 33058536 | Only seven of the survey responders (7/112, 6.3%) reported that they have kept their outpatient clinics open as usual, but they did exercise increased precautions for COVID-19 by following recent guidelines regarding use of personal protective equipment and isolation techniques. | 2020-10-15 |
| 33058704 | The COVID-19 pandemic has triggered a significant growth in government surveillance techniques globally, primarily through the use of cell phone applications. […] However, although these applications can have actionable effects on public health efforts to control pandemics, the participatory or voluntary nature of these measures is obscuring the relationship between health information and traditional government surveillance techniques, potentially preventing effective oversight. […] Public health measures have traditionally been resistant to the integration of government-led intelligence techniques, such as signals intelligence (SIGINT), because of ethical and legal issues arising from the nature of surveillance techniques.We explore this rise of participatory SIGINT and its nature as an extension of biosurveillance through 3 drivers: the rise of surveillance capitalism, the exploitation of a public health crisis to obscure state of exception politics with a moral imperative, and the historically enduring nature of emergency-implemented surveillance measures.We conclude that although mobile applications may indeed be useful in containing pandemics, they should be subject to similar oversight and regulation as other government intelligence collection techniques. | 2020-10-15 |
| 33058776 | Although the main focus is on the etiology of this new disease, the genetics of SARS-CoV-2 impacts prevention, diagnosis, prognosis, and the development of therapies. | 2020-10-15 |
| 33058837 | Real-time reverse transcription polymerase chain reaction (real-time RT-PCR) is regarded as a gold-standard method for the diagnosis of COVID-19. […] Therefore, it is important to establish new methods for the preparation of reliable positive controls that are not affected by contamination for the accurate for diagnosis of COVID-19, but it still remains a challenge. […] Therefore, this approach could be integrated into the currrently available COVID-19 test kits and will provide a general method for preparing positive controls in the diagnosis of emerging RNA virus infections. | 2020-10-15 |
| 33058839 | Reverse transcription quantitative PCR (RT-qPCR) has played a vital role in the diagnosis of COVID-19, but the rates of false negatives is not ideal in dealing with this highly infectious virus. […] It is thus necessary to systematically evaluate the clinical performance of the single-, dual-, triple-target detection kits to guide the clinical diagnosis of this disease. […] This study provides a guide when choosing or developing a nucleic acid detection kit for the diagnosis of COVID-19. | 2020-10-15 |
| 33059091 | A raw estimation of the viral load was done evaluating the Ct (cycle threshold) trend obtained from our diagnostic reverse transcriptase real-time PCR test. | 2020-10-15 |
| 33059564 | In the present review, we have highlighted the current biology, epidemiology, various clinical aspects, different diagnostic techniques, clinical symptoms, and management of COVID-19. | 2020-10-16 |
| 33059771 | The virological diagnosis will be confirmed by detection of SARS-CoV-2 nucleic acid in a clinical sample. | 2020-10-16 |
| 33059811 | To study the expression of angiotensin-converting enzyme 2 (ACE2) and other key molecules of the RAS pathway in normal mice at different developmental stages, and to provide ideas for understanding the infection mechanism of coronavirus disease 2019 (COVID-19) as well as the diagnosis and treatment of children with COVID-19. | 2020-10-16 |
| 33060093 | Individual information on age, sex, occupation, residence location, date of illness onset, date of diagnosis and clinical outcome was extracted. | 2020-10-16 |
| 33060143 | A diagnosis of COVID-19 central nervous system vasculopathy was made. | 2020-10-16 |
| 33060304 | To identify shared and distinct features of giant cell arteritis (GCA) and coronavirus disease 2019 (COVID-19) to reduce diagnostic errors that could cause delays in correct treatment. […] Physicians should be aware of the possibility of diagnostic confusion. | 2020-10-16 |
| 33060516 | Significant diagnostic and treatment uncertainty remain, and clinicians should maintain a broad differential when evaluating patients for multisystem inflammatory syndrome in children, as antibiotic-susceptible infections such as murine typhus may present similarly. | 2020-10-16 |
| 33060679 | Intracardiac three-dimensional echocardiography is a feasible alternative to the traditional techniques for implantation of an Impella CP device but careful consideration must be given to the potential limitations and complications of this technique. | 2020-10-16 |
| 33060844 | In this Consensus Statement, the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI based on current literature. | 2020-10-16 |
| 33060875 | In the current epidemic era of COVID-19, health care staff should strongly become aware of SARS-CoV-2 infection as an essential diagnosis to get away misdiagnosis and prevention of transmission. | 2020-10-16 |
| 33061392 | In addition, hospital chart data of patients referred for neurological evaluation during weeks 12-15/2020 when the pandemic began impacting on public life in Germany were analysed regarding demographic information, chief complaints, modes of presentation and disposition and ED discharge diagnosis. | 2020-10-16 |
| 33061486 | This study was carried out to address this paucity of data and reported discrepancies in diagnostic accuracy for saliva samples. genes was used to detect the presence of the SARS-CoV-2 virus. […] The findings suggest good diagnostic accuracy for saliva and feasibility of utilization of specimen without transport media for SARS-CoV-2 RT-PCR. | 2020-10-16 |
| 33061518 | Colonoscopy is a gold standard for screening and diagnosis of colorectal cancer (CRC). […] Most commonly, Google users searched for details on colonoscopy techniques (Australia, Canada, Ireland, NZ), anesthesia during the procedure (Poland), facility performing colonoscopy (UK, US). | 2020-10-16 |
| 33061542 | This case highlights the need for a prompt clinical, laboratory, and radiological evaluation to allow a correct diagnosis and start a specific therapy. | 2020-10-16 |
| 33061588 | Impacts of COVID-19 in cancer care include interruptions of life-saving therapies, distraction effects, and diagnostic overshadowing that involve diverting attention to the pandemic rather than to cancer patients and disruptions of primary palliative care to patients due to forced quarantine. | 2020-10-16 |
| 33061699 | As a follow-up strategy for patients after CABG surgery, cardiac biomarkers and CTA could also be helpful to the diagnosis of COVID-19. | 2020-10-16 |
| 33061927 | Notwithstanding several challenges related to internet access, computer skills, limited evidence base and regulatory and data protection issues, digital biomarkers collected remotely have significant potential for diagnosis and symptom management in older adults and we propose a framework and pathway for how technologies can be implemented to support remote memory clinics. | 2020-10-16 |
| 33062065 | We conducted a retrospective study using a prospectively maintained database of patients admitted to our hospital between 25 February 2020 and 9 April 2020 with a confirmed diagnosis of COVID-19 pneumonia. […] The mortality rate of the total number of cancer patients is about twice as high as that of non-oncological patients admitted to our hospital with a diagnosis of COVID-19. | 2020-10-16 |
| 33062076 | The impact of molecular detection of pathogens is significant in acute-care settings where rapid and accurate diagnostic measures are critical for decisions in patient treatment and outcomes of infectious diseases. […] Given the devastating impact on medical services and the scale of demand for diagnostic testing of COVID-19, it has been proposed that academic settings such as basic research departments in university/college can be engaged in diagnosing, especially in university hospitals or academic medical centers. […] In collaboration with established diagnostic laboratories, academic facilities can divert their function to detecting virus from patients with suspected COVID-19, adopting existing specialized expertise in virus handling, molecular work, and data analysis. […] This review provides an overview of the general principles, diagnostic value, and limitations of COVID-19 diagnosis platforms in Japan, in particular in-house testing at academic settings. | 2020-10-16 |
| 33062082 | To explore the clinical characteristics of patients with different severity in the early outbreak of COVID-19, hoping to provide reference for clinical diagnosis and treatment. | 2020-10-16 |
| 33062129 | Radiology has a key role to play in the diagnosis and management of COVID-19 as literature from Wuhan and Italy demonstrates. […] We therefore share some critical knowledge and practice areas for radiological suspicion and diagnosis. | 2020-10-16 |
| 33062453 | On the other hand, deep learning (DL) techniques and especially the convolutional neural network (CNN) can classify COVID-19 and non-COVID-19 cases. […] In addition, DL techniques that use CT images can deliver an accurate diagnosis faster than the RT-PCR test, which consequently saves time for disease control and provides an efficient computer-aided diagnosis (CAD) system. […] The CAD systems in the literature are based on either individual CNN or two-fused CNNs; one used for segmentation and the other for classification and diagnosis. | 2020-10-16 |
| 33062483 | COVID-19 should be suspected in patients presenting with neurological abnormalities and should be included in the differential diagnosis to prevent further virus transmission. | 2020-10-16 |
| 33062492 | Methods The Get with the Guidelines National Stroke Database was reviewed to assess patients presenting with a final diagnosis of ischemic stroke, transient ischemic attack (TIA), subarachnoid hemorrhage (SAH), or spontaneous/nontraumatic intraparenchymal hemorrhage (IPH). | 2020-10-16 |
| 33062530 | Results A total of 627 patients with COVID-19 diagnosis (334 were outpatient, 293 were inpatient) were included from a total of 20 organizations across the United States. | 2020-10-16 |
| 33062712 | Severity of COVID-19 was defined based on the diagnostic and treatment guideline for SARS-CoV-2 issued by Chinese National Health Committee. | 2020-10-16 |
| 33063030 | The list of authorized devices varies widely in complexity, from automated bagging techniques to repurposed sleep apnea machines. | 2020-10-16 |
| 33063040 | For patients, diagnostics are an integral part of a full medical history, physical examinations, blood tests, and diagnostic imaging. […] Here, we review current approaches to the molecular diagnosis of coronavirus disease 2019. | 2020-10-16 |
| 33063041 | Diagnosis of acute respiratory distress syndrome was associated with significantly elevated serum interleukin-6 and interleukin-1β on the day of diagnosis. and static lung compliance is specific to severe acute respiratory syndrome coronavirus 2 infection in critically ill patients with respiratory failure. | 2020-10-16 |
| 33063048 | Forecasting techniques can be inculcated thereby assisting in designing better strategies and in taking productive decisions. […] These techniques assess the situations of the past thereby enabling better predictions about the situation to occur in the future. […] Forecasting techniques play a very important role in yielding accurate predictions. […] This study categorizes forecasting techniques into two types, namely, stochastic theory mathematical models and data science/machine learning techniques. […] These techniques and parameters used for forecasting are extensively studied in this work. […] However, forecasting techniques come with their own set of challenges (technical and generic). | 2020-10-16 |
| 33063049 | It is now evident that the world needs a speedy and quicker solution to contain and tackle the further spread of COVID-19 across the world with the aid of non-clinical approaches such as data mining approaches, augmented intelligence and other artificial intelligence techniques so as to mitigate the huge burden on the healthcare system while providing the best possible means for patients’ diagnosis and prognosis of the 2019-nCoV pandemic effectively. | 2020-10-16 |
| 33063054 |
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2020-10-16 |
| 33063233 | This study has aimed to evaluate the use pool of samples as a strategy to optimize the diagnostic of SARS-CoV-2 by RT-qPCR. […] These results suggest that pooling of samples before RNA extraction is preferable in terms of diagnostic for SARS-CoV-2. | 2020-10-16 |
| 33063824 | Notably, a novel serological test for antibodies against the receptor binding domain of SARS-CoV-2 (anti-RBD) showed 100% of our asymptomatic cohort remained seropositive between 3 to 6 weeks post-diagnosis. | 2020-10-16 |
| 33063927 | Patients with IBD are demonstrated to experience concern related to their diagnosis and medications. | 2020-10-16 |
| 33064102 | Digitalization is a disruptive technology that changes the way we deliver diagnostic procedures and treatments in medicine. | 2020-10-16 |
| 33064340 | Plenty of serologic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed so far, thus documenting the importance of evaluating the relevant features of the immune response to this viral agent. […] In the present study, we firstly compared two serologic tests on serum samples collected at two different time points from 46 laboratory-confirmed coronavirus disease-2019 (COVID-19) subjects. […] In this context, great efforts are still necessary for investigating antibody kinetics to develop novel diagnostic algorithms. | 2020-10-16 |
| 33064676 | The variable most associated with contagion was the exposure to a relative with a confirmed diagnosis of COVID-19. | 2020-10-16 |
| 33064678 | Diagnostic testing for coronavirus disease (COVID)-19 is performed using nasopharyngeal swabs. […] These results support the idea of the use of saliva as an alternative specimen for diagnostic testing for COVID-19. | 2020-10-16 |
| 33064898 | The aim of this study was to examine the diagnostic yield of colonoscopy by faecal haemoglobin (f-Hb) concentration in symptomatic patients assessed in primary care by faecal immunochemical testing (FIT). | 2020-10-16 |
| 33065184 | Effective doses are of the same order of magnitude as the higher-dose interventional radiology techniques. | 2020-10-16 |
| 33065193 | Early diagnosis and isolation of COVID-19 patients would help to reduce transmission. | 2020-10-16 |
| 33065315 | An integrated diagnostic algorithm in SARS-CoV-2-infected patients with suspected cardiac involvement (laboratory findings of myocardial injury and electrocardiographic changes) may help to avoid unnecessary examinations and minimize the risk of operator infection. […] Computed tomography (CT) through its multiple applications (chest CT; CT pulmonary angiography and coronary CT angiography; late iodine enhancement CT) and cardiac magnetic resonance might be helpful in reinforcing or redirecting diagnostic hypothesis emerged by other clinical, electrocardiographic and echocardiographic findings. […] The current pandemic makes it challenging to perform serial invasive and non-invasive diagnostic testing in COVID-19 patients and high serum troponin level. | 2020-10-16 |
| 33065387 | The proposed model is evaluated and compared with other image segmentation techniques using a dataset of 1369 patients including 449 patients with COVID-19, 425 normal ones, 98 with lung cancer and 397 of different kinds of pathology. | 2020-10-16 |
| 33065421 | Twenty to 30% indicated that their patients had experienced a flare or delay in diagnosis/intervention due to postponed appointments.53% mentioned use of phone calls/smartphone applications while 47% shifted towards video consultations for patient care. | 2020-10-16 |
| 33065461 | The COVID-19 pandemic has disrupted standard hospital operations and diagnostic radiology resident education at academic medical centers across the country. […] We describe our experience adapting to the challenges in educational interruptions and clinical work reassignments of 41 interventional and diagnostic radiology residents at a large academic center. | 2020-10-16 |
| 33065551 | The aim of this study was to distinguish between severe and non-severe patients in early diagnosis. […] May be CD45 could increase the diagnostic sensitivity. | 2020-10-16 |
| 33065808 | Describe in detail the differential diagnosis, diagnosis, clinical management, and cure of this case. | 2020-10-17 |
| 33065821 | The data are self-report and not diagnostic. | 2020-10-17 |
| 33066057 | (SARS-CoV-2) were studied in patients up to 165 days after PCR diagnosis of infection. […] Sensitivities, specificities, and diagnostic accuracies ranged between 80.8-96.3%, 96.0-100%, and 93.7-99.2%, respectively. | 2020-10-17 |
| 33066177 | The patients showed significant hysteresis from the onset of symptoms to hospitalization and then to diagnosis. | 2020-10-17 |
| 33066390 | However, it remains unknown whether the degree of coagulopathy can be used in order to predict the outcome, establish a diagnosis or guide anticoagulant therapy. | 2020-10-17 |
| 33066701 | Sequencing the viral genome as the outbreak progresses is important, particularly in the identification of emerging isolates with different pathogenic potential and to identify whether nucleotide changes in the genome will impair clinical diagnostic tools such as real-time PCR assays. | 2020-10-17 |
| 33066908 | We assessed patients with coronavirus disease 2019 and a diagnosis of posterior reversible encephalopathy syndrome at our institution from April 1 to June 24, 2020. | 2020-10-17 |
| 33066917 | Final diagnosis was determined after full diagnostic work-up unless impossible due to death. […] After the diagnostic work-up, in 60.0% ischemic and all hemorrhagic strokes patients an etiology non-related with COVID-19 was identified. | 2020-10-17 |
| 33067026 | Thoracic ultrasound has been shown to be useful in the diagnosis of COVID-19 pulmonary involvement. | 2020-10-17 |
| 33067060 | We included patients with bilateral infiltrates on chest imaging, COVID-19 testing performed, and/or COVID-19 suspected as the primary diagnosis. | 2020-10-17 |
| 33067061 | In this retrospective cohort study, patients with confirmed diagnosis of COVID-19 and AHRF receiving NIV in general wards were recruited from two university-affiliated hospitals. | 2020-10-17 |
| 33067112 | Isolation, hygiene measure, diagnosis, and treatment are the most efficient ways of prevention and intervention nowadays. | 2020-10-17 |
| 33067270 | Algorithms employing a combination of the IgG responses to N and S antigens result in high diagnostic accuracy (100%) by as early as 10 DPSO. | 2020-10-17 |
| 33067538 | This study aimed to develop and validate computer-aided diagnosis (CXDx) system for classification between COVID-19 pneumonia, non-COVID-19 pneumonia, and the healthy on chest X-ray (CXR) images. | 2020-10-17 |
| 33067676 | We assessed PCR variations in the SARS-CoV-2 diagnosis taking into account public genome sequences and diagnosis kits used by different countries. | 2020-10-17 |
| 33067713 | • There was a mixed response to whether the parents should be told the genotype (assuming the CF centre knew), and thus the CF diagnosis before the confirmatory sweat test was carried out. | 2020-10-17 |
| 33067888 | Serological test for SARS-CoV-2 antibody can improve early diagnosis of COVID-19 and serves as a valuable supplement to RNA detection. […] From 3 medical institutions across China, serum or plasma of 170 patients with confirmed COVID-19 diagnosis and 300 normal controls were collected and tested with the strip. […] AUC and kappa coefficient were 0.958 and 0.926, respectively, which showed the consistency of the test results with the standard diagnosis. […] The rapid, easy-to-use SARS-CoV-2 IgG/IgM combined antibody test kit has a superior performance, which can help with accurate diagnosis and thus timely treatment and isolation of COVID-19 patients, that contributes to the better control of the global pandemic. | 2020-10-17 |
| 33067892 | Morphological findings were then correlated with several important clinical data, and the HScore (probability of having a reactive hemophagocytic syndrome) was calculated to posthumously confirm the diagnosis of secondary haemophagocytic lymphohistiocytosis. | 2020-10-17 |
| 33067931 | Thus, there are no specific recommendations for the diagnosis, management, and treatment of patients with genetic disorders during the COVID-19 or other pandemics. | 2020-10-17 |
| 33068195 | The outbreak of the coronavirus disease 2019 (COVID-19) has had profound impact on health care not only for its direct effects, but also because it deeply influenced the whole clinical practice and diagnostic pathways, particularly in the acute setting. | 2020-10-17 |
| 33068246 | In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. | 2020-10-17 |
| 33068310 | Computed tomography (CT) can be effective for the early screening and diagnosis of COVID-19. | 2020-10-17 |
| 33068341 | To establish and promote the non-contact doctor-patient interactive diagnosis and treatment mode based on mobile internet for the treatment of coronavirus disease 2019 (COVID-19) with moxibustion therapy, and to observe the feasibility and effectiveness of the model in the pandemic. deficiency of spleen and lung), Dazhui (GV 14), Feishu (BL 13), Geshu (BL 17), Zusanli (ST 36) and Kongzui (LU 6) were used. | 2020-10-17 |
| 33068489 | Faecal immunochemical testing (FIT) was implemented for triage to make optimum use of limited diagnostic resources. […] Twelve of the 14 patients with a CRC diagnosis had provided samples; all 12 had FIT ≥10 μg/g and were offered fast-track investigations. | 2020-10-17 |
| 33068757 | This study estimates these parameters to evaluate the impact of confirmatory testing and to improve clinical diagnosis, epidemiological estimation and interpretation of vaccine trials. | 2020-10-17 |
| 33069093 | These markers can be used for the diagnosis of Guillain-Barré syndrome (GBS). | 2020-10-17 |
| 33069383 | Our aim was to discuss the pathophysiological rationale underlying the existence of SARS-CoV-2 myocarditis and to analyze the literature data regarding the diagnosis and treatment of this particular entity. | 2020-10-18 |
| 33069385 | Over the past ten years, cardiac MRI has become an indispensable tool for acute myocarditis diagnosis. […] The 2020 ESC guidelines give a class I recommendation to its use in the setting of MINOCA for differential diagnosis between acute myocardial infarction, myocarditis, Tako-Tsubo and other cardiac pathologies, in order to improve therapeutic management and follow-up. […] This article describes the technical characteristics of MRI in myocarditis (Lake Louise diagnostic criteria and criteria based on myocardial tissue mapping), the main differential diagnoses, the prognostic value and addresses the issue of myocarditis in the setting of COVID-19. | 2020-10-18 |
| 33069489 | The diagnosis was already known in 1 patient, while the other 10 developed the disease in an average of 25 days after the intervention and 16,6 days after discharge. | 2020-10-18 |
| 33069704 | A set of statistical techniques were used to analyze the responses (n = 1590) from different social groups (healthcare professionals, academicians, students, Government and NGO officials, and businessman) under three scenarios. | 2020-10-18 |
| 33069762 | Sixty-nine RT-PCR positive patients were screened for SARS-CoV-2 IgG antibodies at a median of 44 days post-diagnosis (Inter Quartile Range 31-58) and 80% were positive. | 2020-10-18 |
| 33069846 | Correct and reliable identification of SARS-CoV-2 in COVID-19 suspected patients is essential for diagnosis. | 2020-10-18 |
| 33069957 | The 2019 SARS CoV-2 (COVID-19) pandemic has illustrated the need for rapid and accurate diagnostic tests. | 2020-10-18 |
| 33069986 | Patients with diagnosis of COVID-19 presenting to 5 different hospitals across Greater Manchester between 1st March 2020 and 30th April 2020 who had CTPA were included. | 2020-10-18 |
| 33070027 | In each case, however, the duration of time until diagnosis was delayed due to issues that have arisen because of the COVID-19 pandemic. | 2020-10-18 |
| 33070043 | Employment and shorter time since diagnosis were associated with lower odds of a ≥ 1 MCID increase. | 2020-10-18 |
| 33070355 | Early diagnosis and treatment of retinoblastoma (Rb), the most common intraocular malignancy, can save both the child’s life and vision. | 2020-10-18 |
| 33070501 | While the number of cases of SARS-CoV-2 in Africa compared to other continents has so far been low, there are concerns about under-reporting, inadequate diagnostic tools, and insufficient treatment facilities. | 2020-10-18 |
| 33070540 | Here, we review several cardiovascular applications of machine learning and artificial intelligence and their potential applications to cardiovascular diagnosis, prognosis, and therapy in COVID-19 infection. | 2020-10-19 |
| 33070578 | Molecular techniques are the “gold standard” for the diagnosis of SARS-CoV-2 infection. […] However, the massive use of these techniques has generated some problems. […] Antigen detection tests are also direct diagnostic methods, with the advantage of obtaining the result in a few minutes and at the very “pointof-care”. | 2020-10-19 |
| 33070766 | The use of RT-PCR alone as the sole diagnostic method for surveillance during an acute outbreak is insufficient to grab the full extent of the outbreak. | 2020-10-19 |
| 33070775 | Multivariate logistic regression was used to evaluate the associations between maternal COVID-19 diagnosis and adverse birth outcomes. […] Compared to pregnant women without COVID-19, pregnant women with a confirmed COVID-19 diagnosis had an increased risk of preterm birth (OR 3.34, 95% CI 1.60-7.00) and cesarean section (OR 3.63, 95% CI 1.95-6.76). | 2020-10-19 |
| 33070790 | Understanding of cardiogenic effects of COVID-19 can help minimise the delay in diagnosis. | 2020-10-19 |
| 33070890 | COVID-19 diagnosis is made with RT-PCR, but many other complementary exams may be used to guide clinical practice, such as Chest Computerized Tomography (CT), showing ground glass opacities; increase in inflammatory markers, as C-Reactive Protein and Erythrocyte Sedimentation Rate; hemogram might show hypoalbuminemia, thrombocytopenia. | 2020-10-19 |
| 33070904 | This paper illustrates contemporary approaches to critical illness myopathy (CIM), critical illness polyneuropathy (CIP), and critical illness polyneuromyopathy (CIPNM) in older patients, including incidence, risk factors, mechanisms for pathology, diagnosis, contemporary treatment approaches, and outcomes. | 2020-10-19 |
| 33070924 | Hyper acute diagnosis and treatment are key factors which decrease mortality and morbidity in stroke patients. | 2020-10-19 |
| 33070955 | These include their utility for the diagnosis of acute SARS-CoV-2 infection, past infection or exposure, correlation with immunity and the effective duration of immunity. […] The EUROIMMUN Anti-SARS-CoV-2 IgA lacked specificity for acute diagnosis and all IgM assays offered poor diagnostic utility. | 2020-10-19 |
| 33070986 | Among the actions that have been implemented are: clinical and microbiological surveillance, promotion of rational and controlled use of antibiotics, AMR stewardship programs in hospitals, development of tools for rapid diagnosis of infectious diseases to establish prompt and adequate treatment, and radically improving vaccination strategies. […] The current COVID-19 pandemic has placed disproportionate demands on the healthcare infrastructure and economy worldwide, which will negatively impact on the availability of materials as well as the technical capacity for diagnosis, patient care, and treatment of both COVID-19 and non-COVID-19 patients. | 2020-10-19 |
| 33071007 | Among those not tested, 0.3% received a probable COVID-19 diagnosis from a physician. | 2020-10-19 |
| 33071210 | Since there is no specific and effective treatment; early diagnosis and optimal isolation of the patient are of vital importance. […] Real-time polymerase chain reaction-based (RT-PCR) analyses do not achieve sufficient sensitivity in the diagnosis of the disease. […] The diagnostic sensitivity of LDH/Lymphocyte ratio, which is the main purpose of the study, was analyzed statistically. […] In order to test the effectiveness of LDH/Lymphocyte ratio for COVID-19 for diagnostic purposes, CT results were considered as gold standard. […] LDH/Lymphocyte ratio was analyzed in terms of diagnosis and mortality with using specific CT involvement as gold standard method which was found to be a more sensitive due to PCR false negativity; 0.06 and 0.21 were obtained as cut off values for diagnosis and mortality. | 2020-10-19 |
| 33071303 | As clubfoot clinics begin phased re-opening, we describe various innovative techniques to protect patients and healthcare providers during delivery of clubfoot treatment services. […] We have utilized these innovative techniques in 43 consecutive patients since clinic re-opening and are satisfied that they are effective, economical and easily reproducible even in countries with limited resources. […] Innovative techniques, which have the potential to reduce the risk of disease transmission, will help in the rapid recovery of clubfoot treatment services as countries emerge from months of lockdown. | 2020-10-19 |
| 33071404 | These questions concern the impact on organisational design, the workers’ ability to conduct a diagnosis of a child’s care context, and what knowledge they could draw upon, as well as the decision itself. | 2020-10-19 |
| 33071458 | The Sigmoid function reflecting the cumulative effect is used to characterize the model-based diagnosis rate, cure rate and mortality rate. | 2020-10-19 |
| 33071468 | Our aim is to update the physicians working with COVID-19 patients about this potential complication and hope that understanding of these proposed mechanisms can provide an opportunity for the physicians for early diagnosis or even better, help prevent this complication. | 2020-10-19 |
| 33071481 | A multidisciplinary approach needs to be followed for diagnosis, treatment and tracking, especially between medical and computer sciences, so, a common ground is available to facilitate the research work at a faster pace. […] With this in mind, this survey paper aimed to explore and understand how and which different technological tools and techniques have been used within the context of COVID-19. […] The analysis is widened by investigating Artificial Intelligence (AI) approaches for the diagnosis, anticipate infection and mortality rate by tracing contacts and targeted drug designing. […] Moreover, the impact of different kinds of medical data used in diagnosis, prognosis and pandemic analysis is also provided. | 2020-10-19 |
| 33071558 | SARS-CoV-2 antibodies were measured with the BIOSYNEX COVID-19 BSS IgM/IgG test (BIOSYNEX, Illkirch-Graffenstaden, France) and the MAGLUMI CLIA (IgM and IgG) (SNIBE - Shenzhen New Industries Biomedical Engineering, Shenzhen, China) in 70 serum samples from patients with PCR-confirmed diagnosis. | 2020-10-19 |
| 33071895 | The second part of the article discusses applied practice considerations, presenting various techniques and methodologies which practitioners can apply while consulting from a change-based perspective. | 2020-10-19 |
| 33071996 | Here, we discuss the current use of proteomics in three major application areas: (i) virus-protein interactomics, (ii) differential proteotyping to map the virus-induced changes in different cell types, and (iii) diagnostic methods for coronavirus infectious disease 2019 (COVID-19). | 2020-10-19 |
| 33072189 | A brief literature overview of adapted changes regarding new safety techniques, processing, sampling techniques implemented by the cytology laboratories in the this part of the world is presented. | 2020-10-19 |
| 33072190 | Despite the definite evidence of effective use of SFJDC in the diagnosis and treatment of pneumonia caused by SARS-CoV-2, the underlying action mechanism remains unknown. | 2020-10-19 |
| 33072338 | Finally, after selecting a screened set of epitopes, we designed a novel virus-like particle vaccine optimized to be produced in plants by using molecular farming biotechnology techniques. | 2020-10-19 |
| 33072432 | As the SARS-CoV-2 (COVID-19) pandemic spreads rapidly, there is need for a diagnostic test with high accuracy to detect infected individuals especially those without symptoms. | 2020-10-19 |
| 33072452 | This case highlights an atypical presentation of a possible COVID-19 infection, the urgency to have additional diagnostic tests apart from rRT-PCR, and the necessity to use the appropriate personal protective equipment (PPE) during the pandemic. | 2020-10-19 |
| 33072634 | Diagnosis of diabetes mellitus was self-reported. | 2020-10-19 |
| 33072656 | Real-time polymerase chain reaction (RT-PCR) and chest computed tomography (CT) scan are main diagnostic modalities of coronavirus disease 2019 (COVID-19). […] Therefore, the present meta-analysis was designed to answer to the question whether CT scan can be used in diagnosis of COVID-19 or not. […] Two researchers gathered the data of diagnostic accuracy studies that had attempted to evaluate sensitivity and specificity of CT scan in diagnosis of COVID-19. […] Sensitivity, specificity, and diagnostic odds ratio of this sign was calculated to be 0.90, 0.89, and 20, respectively. […] However, it is suggested to make the final diagnosis based on both CT scan and RT-PCR, as none of the two diagnostic modalities are reliable alone. | 2020-10-19 |
| 33072684 | This case report discusses patients where the initial presenting symptoms seemed to be exclusive to meningitis but the later diagnosis was COVID-19. […] It is important to increase awareness of these rare presentations in physicians and healthcare workers and facilitate early diagnosis and management to prevent the horizontal spread of the disease. | 2020-10-19 |
| 33073072 | Third, novel techniques have identified previously uncharacterized immune cell populations that may play a functional role in these processes. | 2020-10-19 |
| 33073258 | The gold standard for COVID-19 diagnosis is detection of viral RNA through PCR. | 2020-10-19 |
| 33073312 | In this work, we put forth key observations in the functionality of current methods for SARS-CoV-2 diagnostic testing. | 2020-10-19 |
| 33073555 | A multidisciplinary approach to autopsy, including light microscopy examination along with the detection of viral proteins and/or RNA in tissue samples through ancillary techniques, provided crucial information on the mechanisms underlying the often-heterogeneous clinical picture of COVID-19. | 2020-10-19 |
| 33073557 | Biobanks are imperative infrastructures, particularly during outbreaks, when there is an obligation to acquire and share knowledge as quick as possible to allow for implementation of science-based preventive, diagnostic, prognostic and therapeutic strategies. | 2020-10-19 |
| 33073910 | Saliva may be a new source of diagnostic specimens for critically ill patients, since it can be easily collected without any invasive procedures. | 2020-10-19 |
| 33073946 | An expeditious laboratory diagnosis has a pivotal role in patient management and prevention. | 2020-10-19 |
| 33073969 | Overall, the parameters CRP, D-dimer, and CBC are more important in diagnosis. | 2020-10-19 |
| 33073982 | The diagnostic tool achieved 100% consistency with the “gold standard” polymerase chain reaction in detecting 54 real clinical samples. […] The integrated system, with its simplicity, is urgently needed for the diagnosis of SARS-CoV-2 during the COVID-19 pandemic. | 2020-10-19 |
| 33074240 | Living in care facilities and diagnosis of AD were independently associated with a higher probability of death. | 2020-10-19 |
| 33074525 | The diagnosis may be challenging due to overlapping features between pulmonary embolism and severe COVID-19 disease, such as dyspnoea, high concentration of D-dimers, right ventricle with dysfunction or enlargement, and acute respiratory distress syndrome. […] Here, we review the mechanistic relationships between inflammation and thrombosis, discuss the macrovascular and microvascular complications and summarize the prophylaxis, diagnosis and treatment of thromboembolism in patients affected by COVID-19. | 2020-10-19 |
| 33074833 | We, therefore, recommend that future solutions should consider the use of modern privacy-enhancing techniques (eg, from the area of secure multiparty computing and differential privacy). | 2020-10-19 |
| 33074885 | The early colorectal tropism of SARS-CoV-2 may have major implications on prevention, diagnosis, and treatment of COVID-19. | 2020-10-19 |
| 33074904 | To evaluate the overall survival of patients with operable stage IA non-small-cell lung cancer (NSCLC) who undergo “early” SBRT (within 0-30 days after diagnosis) versus “delayed” surgery (90-120 days after diagnosis). […] Multivariable Cox proportional hazards modeling and propensity score-matched analysis was used to compare the overall survival of patients with stage IA NSCLC in the National Cancer Data Base from 2004 to 2015 who underwent “early” SBRT (0-30 days after diagnosis) versus that of patients who underwent “delayed” wedge resection (90-120 days after diagnosis). | 2020-10-19 |
| 33075043 | One hundred and forty-eight patients were included, 71 (48%) received the diagnosis of pneumonia. | 2020-10-19 |
| 33075636 | The clinical presentation of COVID-19 is very heterogeneous, ranging from asymptomatic to severe, which could lead to the need for mechanical ventilation or even death.We analyzed the serum levels of IL-6 in patients with COVID-19 diagnosis and its relationship with the severity of the disease, the need for mechanical ventilation and with patient mortality. […] IL-6 serum levels appear to be a useful prognostic biomarker in patients with a diagnosis of COVID-19 pneumonia. | 2020-10-19 |
| 33075793 | The yield of BAL for the diagnosis of suspected or confirmed pulmonary SARS-CoV-2 infection is still unknown. […] We aimed to evaluate the diagnostic ratio of BAL in detecting SARS-CoV-2 pulmonary infection in patients undergoing bronchoscopy for different indications as well as describe the clinical, radiological, and endoscopic characteristics of patients with SARS-CoV-2 on BAL. […] Bronchoscopy was performed for suspected SARS-CoV-2 infection (65.5%), alternative diagnosis (12.9%), suspected superinfections (19.8%), and lung atelectasis (1.5%). | 2020-10-19 |
| 33076753 | Radiologists subsequently interpreted all exams and determined the adequacy of the images for diagnosis. | 2020-10-20 |
| 33076794 | A higher percentage of patients admitted during the COVID-19 period were diagnosed as having nonaffective psychotic disorders (52% versus 35%) or bipolar disorder (25% versus 15%), and fewer received a diagnosis of depression (8% versus 16%), anxiety disorder (0% versus 3%), adjustment disorder (0% versus 8%), emotionally unstable personality disorder (6% versus 15%), or any other personality disorder (0% versus 5%) (p=0.01). | 2020-10-20 |
| 33076848 | The primary outcome was all-cause mortality at 60 days after COVID-19 diagnosis. […] By 60 days after COVID-19 diagnosis, 14 patients (0.28%) had died, 10 (0.2%) were still in hospital, and two (0.04%) were still in ICU. | 2020-10-20 |
| 33076874 | However, at multivariable analysis, higher concentrations of hemoglobin (OR, 1.34; 95% CI, 1.11-1.65; P = 0.003) and lower counts of leukocytes (OR, 0.81; 95% CI, 0.72-0.90; P < 0.001) were statistically associated with confirmed COVID-19 diagnosis. […] While mortality rates were similar, patients with confirmed diagnosis were more likely to receive antivirals (95% vs 19.6%, P < 0.001) and to develop ARDS (63% vs 37%, P = 0.003) than those with unconfirmed COVID-19 diagnosis. | 2020-10-20 |
| 33077899 | The rapid spread of COVID-19 necessitates the development of cost-effective technology platforms for the production of vaccines, drugs, and protein reagents for appropriate disease diagnosis and treatment. […] Overall these findings provide a proof-of-concept for using plants as an expression system for the production of SARS-CoV-2 antigens and antibodies or similar other diagnostic reagents against SARS-CoV-2 rapidly, especially during epidemic or pandemic situation. | 2020-10-20 |
| 33078007 | Up to the moment we have just been able to chase the shadow, by integrating medieval systems (quarantine) and hyper-technological systems (i.e., the most advanced resuscitation techniques). | 2020-10-20 |
| 33078010 | The most frequently encountered symptom was fever, present in 76.9% of the symptomatic. 26 people were positive on the diagnostic tests (55.3% of the total examined), 24 of them were symptomatic. | 2020-10-20 |
| 33078030 | RT-PCR diagnosis using throat swab specimens had a failure rate of more than 22% in safely discharging COVID-19 patients who were otherwise still exhaling the SARS-CoV-2 by a rate of estimated ~1400 RNA copies per minute into the air. | 2020-10-20 |
| 33078093 | In this report, the diagnostic dilemmas and the therapeutic challenges due to the overlapping clinical, imaging, and laboratory findings between lupus and COVID-19 pneumonitis are outlined. | 2020-10-20 |
| 33078094 | The domain of medical diagnosis and predictive analytics is one of the key domains of research with enormous dimensions whereby the diseases of different types can be predicted. […] In this research work, the analytics of key points from medical images of the COVID-19 dataset is to be presented using which the diagnosis and predictions can be done for the patients. | 2020-10-20 |
| 33078138 | Eligible patients should have a microbiological (positive test on RT-PCR assay from a nasal swab) or an epidemiological diagnosis of severe COVID-19. | 2020-10-20 |
| 33078221 | While reliable nucleic acid-based diagnostic assays were rapidly available, only a limited number of validated serological assays were available in the early phase of the pandemic. | 2020-10-20 |
| 33078222 | Different assays demonstrate 41-45% of diagnostic sensitivities and 91-98% of specificities, with substantial agreement (89.3-91.2%), but a high percentage of weak positive results (13-22%) was observed with ICTs. | 2020-10-20 |
| 33078425 | We evaluate the impact of COVID-epidemic in colorectal cancer (CRC) diagnosis during Spain’s state of emergency. […] A new diagnosis of CRC decreased 48% with a higher rate of patients diagnosed in the emergency setting (12.1% vs. | 2020-10-20 |
| 33079693 | Most of the selected articles addressed the use of digital technologies for diagnosis, surveillance, and prevention. […] We report that most of these digital solutions and innovative technologies have been proposed for the diagnosis of COVID-19. […] In particular, within the reviewed articles, we identified numerous suggestions on the use of artificial intelligence (AI)-powered tools for the diagnosis and screening of COVID-19. […] In the field of diagnosis, digital solutions that integrate with traditional methods, such as AI-based diagnostic algorithms based both on imaging and clinical data, appear to be promising. | 2020-10-20 |
| 33079951 | This method was subsequently adopted as the primary sample preparation method in the Groote Schuur Hospital Virology Diagnostic Laboratory in Cape Town, South Africa. | 2020-10-20 |
| 33079969 | All diagnostic codes from the past 5 years of hospitalisation records and all drug codes from prescriptions dispensed during the past 240 days were extracted. | 2020-10-20 |
| 33080031 | For this reason, a diagnostic test able to discriminate SARS-CoV-2 from influenza viruses is urgently needed. […] The test may be an important diagnostic tool for both diagnostic and surveillance purposes during the seasonal influenza activity period. | 2020-10-20 |
| 33080120 | Behaviour change techniques are fundamental to the development of any behaviour change intervention, but surprisingly little is known about their properties. […] Key questions include when, why, how, in which contexts, for which behaviours, in what combinations, compared with what, and for whom behaviour change techniques are typically effective. […] The aims of the present paper are to: (1) articulate the scope of the challenge in understanding the properties of behaviour change techniques, (2) propose means by which to tackle this problem, and (3) call scientists to action. […] Psychol., e12468) was used to elicit and distil the judgements of experts on how best to tackle the problem of understanding the nature and operation of behaviour change techniques. […] We propose a worldwide network of ‘Centres for Understanding Behaviour Change’ (CUBiC) simultaneously undertaking research to establish what are the single and combined properties of behaviour change techniques across multiple behaviours and populations. […] We additionally provide a first attempt to systematize an approach that CUBiC could use to understand behaviour change techniques and to begin to harness the efforts of researchers worldwide. […] Better understanding of behaviour change techniques is vital for improving behaviour change interventions to tackle global problems such as obesity and recovery from COVID-19. | 2020-10-20 |
| 33080550 | Odor threshold test can be helpful for diagnosis. | 2020-10-20 |
| 33080662 | The Advanced Topics in Molecular Biology Techniques course, designed for upper division undergraduate and graduate students, uses a “journal club” format. | 2020-10-20 |
| 33080676 | The chest computed tomography (CT) characteristics of coronavirus disease 2019 (COVID-19) are important for diagnostic and prognostic purposes. | 2020-10-21 |
| 33080715 | Rapid and sensitive nucleic acid testing is usually used as a basis for diagnosis. | 2020-10-21 |
| 33080725 | Our findings will provide references for clinical diagnosis and treatment and guidance programs for COVID-19. | 2020-10-21 |
| 33080737 | The imaging characteristics of COVID-19 and non-COVID-19 viral pneumonia are different, and the prediction model can further improve the specificity of chest CT diagnosis. | 2020-10-21 |
| 33080869 | We investigate the time from symptom onset to diagnosis and hospitalization or the length of stay (LoS) in the hospital, and whether there are differences in the population. […] The time between symptom onset and hospitalization or diagnosis are similar, with median length between symptom onset and hospitalization ranging between 3 and 10.4 days, depending on the age of the patient (longest delay in age group 20-60 years) and whether or not the patient lives in a nursing home (additional 2 days for patients from nursing home). | 2020-10-21 |
| 33081350 | Here we summarize the recent research on viruses employed as therapy and diagnostic of COVID-19: (i) viral-vector vaccines both in clinical trials and pre-clinical phases; (ii) the use of bacteriophages to find antibodies specific to this virus and some studies of how to use the bacteriophages themselves as a treatment against viral diseases; and finally, (iii) the use of CRISPR-Cas technology both to obtain a fast precise diagnose of the patient and also the possible use of this technology as a cure. | 2020-10-21 |
| 33081700 | According to the diagnosis and treatment guidelines of China, negative reverse transcription-polymerase chain reaction (RT-PCR) is the key criterion for discharging COVID-19 patients. […] The diagnostic performance was evaluated for both cohorts. | 2020-10-21 |
| 33081702 | SARS-CoV-2 RNA detection is the diagnostic criterion for coronavirus disease 2019 (COVID-19). | 2020-10-21 |
| 33081710 | A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. […] We recorded vital signs of patients to correlate clinical and laboratory information and calculated the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of a single swab using RT-LAMP compared with the current standard, RT-PCR, as per Standards for Reporting Diagnostic Accuracy Studies (STARD) guidelines. | 2020-10-21 |
| 33081859 | The other objective is to improve ED staff confidence in managing such patients, and to increase their skills in basic and advanced airway management and proper personal protective equipment (PPE) techniques. | 2020-10-21 |
| 33081869 | Further research is needed to establish patient acceptability, diagnostic accuracy, safety and efficiency of remote models of care for this patient group. | 2020-10-21 |
| 33081888 | To explore the correlation between symptoms and their contribution to syndrome based on syndrome of lung damp-heat accumulation in coronavirus disease 2019 (COVID-19), thus to provide methodological basis for the syndrome diagnosis. […] It could provide methodological basis for the syndrome diagnosis. | 2020-10-21 |
| 33081992 | Case decisions in the cath labs should be individualized, taking into account the risk of 2019 novel coronavirus (COVID-19) exposure versus the risk of delay in diagnosis or therapy. […] Regarding the delay in the invasive management for patients with ACS due to diagnostic testing, there was 100% delay in all surveyed centers with 70% of centers suffering from delay in primary PCI due to awaited testing. | 2020-10-21 |
| 33082264 | The antinucleoprotein and antispike antibodies can be accurately detected in patients during the mid or late stage of infection, and therefore, these assays have not been widely used for early diagnosis of COVID-19. […] Our serological test detecting anti-orf8 antibodies may facilitate the development of early and accurate diagnosis for COVID-19. | 2020-10-21 |
| 33082617 | The difference between supply and demand is substantial to be handled with normal production techniques, especially under social distancing measures in place. | 2020-10-21 |
| 33082630 | Some urological malignancies need early diagnosis and treatment while the diagnosis and treatment of several others can be safely delayed. | 2020-10-21 |
| 33082999 | Oral fluid-based surveillance reflects the adaptation of conventional testing methods to an alternative diagnostic specimen. | 2020-10-21 |
| 33083156 | The Food and Drug Administration and other health agencies have declared Emergency Use Authorization to develop diagnostic methods for COVID-19 and fulfill the demand. | 2020-10-21 |
| 33083172 | The clinical presentation, diagnosis, and treatment of coronavirus disease 2019 (COVID-19) encephalitis are still being characterized. | 2020-10-21 |
| 33083203 | Most Human taeniasis are asymptomatic or associated with vague clinical manifestations, but cases of unusual migration of these parasites have been described. . through the gastro-jejunal anastomosis into the gastric stump.Preoperative evaluation (history, physical examination and imaging features) led to gastric cancer diagnosis and hindered the recognition of the taeniasis because of similar clinical presentations and the need to start quickly a therapeutic oncological strategy. | 2020-10-21 |
| 33083367 | SARS-CoV-2 infection is a diagnostic challenge in some patients with atypical clinical presentations, who may have MIS-C/PIMS-TS.Physicians should be aware of this condition when evaluating teenagers and young adults with COVID-19. | 2020-10-21 |
| 33083369 | We discuss the challenge of establishing the diagnosis as well as the management of tissue-invasive gastrointestinal CMV infection (TI-GI CMV) simulating vascular involvement and intestinal obstruction in a critically ill patient. | 2020-10-21 |
| 33083395 | The global outbreak of human severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection represents an urgent need for readily available, accurate and rapid diagnostic tests. […] Nucleic acid testing of respiratory tract specimens for SARS-CoV-2 is the current gold standard for diagnosis of coronavirus disease 2019 (COVID-19). […] However, the diagnostic accuracy of reverse transcription polymerase chain reaction (RT-PCR) tests for detecting SARS-CoV-2 nucleic acid may be lower than optimal. […] The detection of SARS-CoV-2-specific antibodies should be used as a serological non-invasive tool for the diagnosis and management of SARS-CoV-2 infection. […] To investigate the diagnostic value of SARS-CoV-2 IgM/IgG and nucleic acid detection in COVID-19. 2 test was used to compare differences between categorical variables. […] Our data indicate that serological IgM/IgG antibody combined test had high sensitivity and specificity for the diagnosis of SARS-CoV-2 infection, and can be used in combination with RT-PCR for the diagnosis of SARS-CoV-2 infection. | 2020-10-21 |
| 33083516 | Patients and clinicians can be reassured that prescription of an ACEi or ARB at the time of COVID-19 diagnosis is not harmful. | 2020-10-21 |
| 33083782 | Identifying pathways that are associated with Covid-19 severity that result in pulmonary fibrosis may enable early diagnosis and individualized treatment for these patients to prevent or reduce irreversible fibrotic damage to the lung. | 2020-10-21 |
| 33084260 | The gold standard for diagnosis of the COVID-19 infection is real-time reverse transcription polymerase chain reaction. […] Radiological investigations (chest X-ray or high-resolution computerized tomography [CT]) can be helpful both for diagnosis and management, but they have many limitations. […] In this review, we present the advantages, techniques, and limitations of the use of LUS during the COVID-19 pandemic, with specific focus on pregnancy. | 2020-10-21 |
| 33084566 | We provide a case series of CAPA, adding 20 cases to the literature, with review of pathophysiology, diagnosis, and outcomes. […] Prospective studies reporting poor outcomes in CAPA patients underscore the urgent need for strategies to improve diagnosis, prevention, and therapy. | 2020-10-21 |
| 33085218 | Lung ultrasound (LUS) has been successfully used in the diagnosis of different pulmonary diseases. […] Present study design to determine the diagnostic value of LUS in the evaluation of children with novel coronavirus disease 2019 (COVID-19). […] LUS results were compared with chest X-ray and CT findings and diagnostic performance was determined. […] Chest X-ray and LUS were performed on all and chest CT was performed on 28 (70%) patients at the time of diagnosis. […] LUS confirmed the diagnosis of pulmonary involvement in 10 of 12 patients with positive CT findings. […] LUS might be a useful tool in the diagnostic steps of children with COVID-19. […] A reduction in chest CT assessments may be possible when LUS is used in the initial diagnostic steps for these children. | 2020-10-21 |
| 33085538 | The need for reliable diagnostic methods, treatments and vaccines for COVID-19 is the major worldwide urgency. | 2020-10-21 |
| 33085645 | An integrated multi-feature model (RT-PCR, CT features, and blood lymphocyte percentage) established with random forest algorism showed the diagnostic accuracy of 92.0% (95% CI: 73.9 - 99.1) in the training set, and 96. […] In conclusion, the developed multivariate model based on machine learning techniques could be an efficient tool for COVID-19 screening in nonendemic regions with a high rate of influenza and CAP in the post-COVID-19 era. | 2020-10-21 |
| 33085973 | High priority endoscopies during pandemic include acute gastrointestinal bleed, acute severe ulcerative colitis, new IBD diagnosis, cholangitis in primary sclerosing cholangitis, and partial bowel obstruction. | 2020-10-21 |
| 33086096 | Among individuals with a negative or no previous COVID-19 diagnostic test, myalgias, headache, and loss of appetite were associated with serological reactivity. | 2020-10-21 |
| 33086161 | ABO blood groups is a cheap and affordable test that can be immediately retrieved from COVID-19 patients at the diagnosis. […] We can conclude, on the diagnostic level, that ABO blood groups can be potentially used for risk stratification of affected COVID-19 patients, to anticipate the deterioration of patients at higher risk for complications. | 2020-10-21 |
| 33086403 | Three hundred and seventeen (88%; 95% confidence interval [CI]: 84-91%) patients were receiving thromboprophylaxis at the time of VTE diagnosis. | 2020-10-21 |
| 33086578 | Early diagnosis not only increases the chance of quick recovery but also helps prevent the spread of infections. […] Conventional diagnostic techniques can provide reliable results but have several drawbacks, including costly devices, lengthy wait time, and requirement of trained professionals to operate the devices, making them inaccessible in low-resource settings. […] Thus, a significant effort has been directed towards point-of-care (POC) devices that enable rapid diagnosis of bacterial and viral infections. […] These techniques have been shown to provide rapid, sensitive detection of pathogens. | 2020-10-22 |
| 33086857 | The knowledge of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) shedding is highly relevant to the diagnosis, treatment and follow-up of patients with COVID-19 (coronavirus disease 2019). | 2020-10-22 |
| 33087036 | In recent years, data shared through social media, mobile apps and on other social websites has increased manifolds requiring data mining techniques. | 2020-10-22 |
| 33087037 | This review contribution includes specific information including: 1) An introduction to current research on nanotechnology and related recent patents for COVID-19 responses; 2) Analysis of nonimmunogenic and immunogenic prophylaxis of COVID-19 using Nanotechnology; 3) Tools devoted to detection & diagnosis of coronaviruses and COVID-19: the role of Nanotechnology; and 4) A compilation on the research and patents on nanotechnology dealing with therapeutics & treatments of COVID-19. […] This review offers a general view of the current research investigation and recent patents dealing with aspects of immunogenic and non-immunogenic prophylaxis, detection and diagnosis as well as therapeutics and treatments. | 2020-10-22 |
| 33087440 | Overall, our results highlight the challenges in biomarker-driven diagnosis of CAPA, especially when only limited clinical samples are available for testing, and the importance of a multimodal diagnostic approach involving regular and repeat testing of both serum and respiratory samples. | 2020-10-22 |
| 33088398 | This study explains the importance of differential diagnosis between COVID-19 and other lung diseases. we analyzed in this study, the demographic features, clinical presentations, laboratory data and radiologic findings of the COVID-19 patients in comparison to those with other respiratory infections or diseases. the mean age of all patients was 38.04 years; 35 patients were later confirmed to be positive for SARS-CoV-2 infection. | 2020-10-22 |
| 33088836 | The SARS-CoV-2 pandemic has resulted in unprecedented challenges to veterinary diagnostic laboratories. […] These challenges include partial or complete shutdowns, interrupted courier services, disruptions in workflow and diagnostic testing, new physical distancing practices, protocol development or enhancement for handling samples from high-risk or susceptible species, and fulfilling requirements for pre-test permission approval from state and federal veterinary agencies, all of which have been implemented to prevent or minimize exposure and transmission of SARS-CoV-2 locally or regionally. | 2020-10-22 |
| 33088905 | Diagnosis of viral myocarditis is multifactorial and involves detection of elevated cardiac biomarkers and echocardiographic evidence of cardiomyopathy, in the absence of diseased coronary arteries. | 2020-10-22 |
| 33088910 | This process was extremely complex, due to the limited availability of needed reagents, but outreach to our research scientists and multiple diagnostic laboratory companies, and government officials enabled us to implement both Food and Drug Administration authorized and laboratory-developed testing-based testing protocols. | 2020-10-22 |
| 33088995 | A number of open and crowdsourcing initiatives have sought to address this shortfall by producing equipment such as protective face shields using additive manufacturing techniques such as fused filament fabrication (FFF). […] LSAM offers significant advantages over other additive manufacturing technologies in bridge manufacturing scenarios as a true transition between prototypes and mass production techniques such as injection molding. | 2020-10-22 |
| 33089040 | The diagnosis of A-SCAD was supported by the presence of a mild stenosis in the same coronary segment in the last angiogram performed 3 years previously. | 2020-10-22 |
| 33089052 | The differential diagnosis of acute heart failure in critically ill patients with COVID-19 infection is broad, including sepsis-induced cardiomyopathy, Takotsubo syndrome, viral lymphocytic myocarditis, and acute coronary syndrome. | 2020-10-22 |
| 33089297 | This recommendation will be updated according to the situation of epidemic prevention and control in China and the new relevant diagnosis and treatment plans. | 2020-10-22 |
| 33089298 | This article analyzed the route of infection during diagnosis and treatment of oral diseases. | 2020-10-22 |
| 33089347 | We did not observe any clear increase in the diagnosis of perforated appendicitis during the pandemic period, even in patients who were transferred from other hospitals. | 2020-10-22 |
| 33089674 | It is hoped that these shifts will assist with disease diagnosis, treatment, management, recovery, and rehabilitation with minimal in-person contact. | 2020-10-22 |
| 33089824 | This present proof-of-concept-study yields encouraging results showing a rapid diagnosis of viral infections in nasal breath within 5 min by MCC-IMS. | 2020-10-22 |
| 33089862 | We aimed to establish whether health outcomes and care differed between patients with SCZ and patients without a diagnosis of severe mental illness. […] Cases were patients who had a diagnosis of SCZ. […] Controls were patients who did not have a diagnosis of severe mental illness. […] Our findings report the existence of disparities in health and health care between SCZ patients and patients without a diagnosis of severe mental illness. | 2020-10-22 |
| 33090050 | Predicting the disease severity at time of diagnosis can be helpful in prioritizing hospital admission and resources. […] Predefined risk variables were collected at the time of PCR based diagnosis of the infection. […] We developed and validated a simple score calculated at time of diagnosis that can predict patients with severe COVID-19 disease reliably and that has been validated externally. | 2020-10-22 |
| 33090210 | Optimal and flexible diagnostic strategies are needed to accomplish and sustain the goals of comprehensive pre-procedure surveillance testing. | 2020-10-22 |
| 33090328 | Thus, this system can be a solution for healthcare authorities to ensure the older population’s accessibility to a better medical diagnosis system in the developing countries, especially in the pandemic situation like COVID-19, when in-person monitoring is minimal. | 2020-10-22 |
| 33090353 | The molecular diagnosis of SARS-CoV-2 infection is based on the detection of viral RNA on different biological specimens. […] In the present study, we evaluated the diagnostic accuracy of lung point-of-care ultrasound (POCUS) for SARS-CoV-2 pneumonia in a cohort of symptomatic patients admitted to one emergency department (ED) in a high-prevalence setting. […] Diagnostic accuracy was evaluated using sensitivity, specificity, and positive and negative predictive value. | 2020-10-22 |
| 33090430 | Currently, detection of SARS-CoV-2 RNA is standard in the diagnosis of COVID-19 (2019-nCoV). […] However, reliable and rapid serological diagnostic methods to screen SARS-CoV-2 infected patients, including those who do not have overt symptoms, are urgently needed. […] Here, we attempted to systematically analyze the positive rates and comprehensive diagnostic efficacy of IgM and IgG in response to SARS-CoV-2 infection. […] Using RT-PCR test as reference, the AUCs of IgM, IgG and IgM/IgG in the diagnosis of 2019-nCoV infection were 0.9656, 0.9766, and 0.9838, respectively. […] IgM, IgG and their joint testing exhibited high clinical value in the diagnosis of 2019-nCoV, which may assist in making up for the deficiency of throat swab RNA tests. | 2020-10-22 |
| 33090431 | The survey Safe and Patient Friendly Healthcare suggests early diagnosis as the key to patients recovering from this deadly ailment. | 2020-10-22 |
| 33090435 | We have summarized the mechanisms, efficacy, and side effects of various oxygen therapy techniques and their status or the potential to treat hypoxia in COVID-19 patients. | 2020-10-22 |
| 33090441 | We should identify a safe and clear diagnostic algorithm, possibly combining patient clinical history, troponin levels and cardiac ultrasound findings that could help us in the prediction of myopericarditis. | 2020-10-22 |
| 33090512 | Overall, our findings suggest that SARS-CoV-2 mutations could change viral protein structure, binding affinity and hot spots of the interface, thereby might have impacts on SARS-CoV-2 transmission, diagnosis and treatment of COVID-19. | 2020-10-22 |
| 33090645 | Surprisingly, we can not see that the Authors recommended other diagnostic considerations such a checking for hyperhomocysteinemia in patients with COVID-19. | 2020-10-22 |
| 33090795 | One of the most widely used methods to detect an acute viral infection in clinical specimens is diagnostic real-time polymerase chain reaction. […] However, because of the COVID-19 pandemic, mass-spectrometry-based proteomics is currently being discussed as a potential diagnostic method for viral infections. | 2020-10-22 |
| 33090964 | We extracted related clinical information regarding diagnosis, progression, and outcome for all COVID-19 cases. […] A total of 10,504 patients with a clinical or polymerase chain reaction-confirmed diagnosis of COVID-19 were identified; 5519 (52.5%) were male, with a mean age of 58.2 years (SD 19.7). | 2020-10-22 |
| 33090983 | No on-field team B or team C players or staff members subsequently received a clinical diagnosis of COVID-19. […] Certain MLB health and safety protocols, which include frequent diagnostic testing for rapid case identification, isolation of persons with positive test results, quarantine for close contacts, mask wearing, and social distancing, might have limited COVID-19 transmission between teams. | 2020-10-22 |
| 33091042 | The diagnostic sensitivities of IgM/IgG for ≤14d PSO were 21.4%/35.7~57.1% and increased to 41.252.9%/88.294.1% at >14 d PSO with specificities of 98.5%/94.2% for AFIAS COVID-19 Ab and 100.0%/96.4% for EDI™ Novel Coronavirus COVID-19 ELISA Kit. | 2020-10-22 |
| 33091118 | Here, we describe the strategic objectives and action lines of the European Alliance of Medical Research Infrastructures (AMRI), established to improve the research process and tackle challenges related to diagnostic tests and biomarker development. […] Recommendations include: the creation of a European taskforce for validation of novel diagnostic products, the definition and promotion of criteria for COVID-19 samples biobanking, the identification and validation of biomarkers as clinical endpoints for clinical trials, and the definition of immune biomarker signatures at different stages of the disease. | 2020-10-22 |
| 33091367 | The novel coronavirus (COVID-19) pandemic has led surgical societies to recommend delaying diagnosis and treatment of suspected lung cancer in lesions <2 cm. […] Delaying diagnosis can lead to disease progression, but the impact of this delay on mortality is unknown. | 2020-10-22 |
| 33091399 | The following points mark the particularity of COVID-19 in Africa: (1) insufficient diagnostic capacity (linked to gross national product), (2) a younger population limiting the population at risk and the number of deaths, (3) a favourable climate (hot and humid) which is decreasing viral transmission, (4) some socio-cultural factors that can reduce cases reporting. | 2020-10-22 |
| 33091701 | The number of PE diagnosis among patients with COVID-19 and respiratory deterioration was high; 26% in the ED, 33% in the regular ward and 77% in the ICU respectively. | 2020-10-22 |
| 33091741 | With the rapidly worldwide spread of Coronavirus disease (COVID-19), it is of great importance to conduct early diagnosis of COVID-19 and predict the conversion time that patients possibly convert to the severe stage, for designing effective treatment plans and reducing the clinicians’ workloads. | 2020-10-22 |
| 33091743 | While image analysis of chest computed tomography (CT) for COVID-19 diagnosis has been intensively studied, little work has been performed for image-based patient outcome prediction. | 2020-10-22 |
| 33091766 | For the inverse modeling, we propose Bayesian inversion techniques, which are robust and reliable approaches, in order to estimate the unknown parameters of the epidemiological models. | 2020-10-22 |
| 33091782 | Observational study of outpatient MH/SUD visits January 1st-June 30th, 2018-2020 by: 1) visit diagnosis group, 2) provider type, 3) patient race/ethnicity, 4) insurance, and 5) visit method (telemedicine vs. in-person). […] Despite this, widening diagnostic and racial/ethnic disparities in MH/SUD visit volume during the surge and reopening suggest additional barriers for these vulnerable populations, and warrant continued monitoring and research. | 2020-10-22 |
| 33091835 | Chest computed tomography (CT) is considered a reliable imaging tool for COVID-19 pneumonia diagnosis, while lung ultrasound (LUS) has emerged as a potential alternative to characterize lung involvement. […] The aim of the study was to compare diagnostic performance of admission chest CT and LUS for the diagnosis of COVID-19. […] CT demonstrated better performance than LUS in diagnosis of COVID-19, both in HP (AUC 0.75 vs 0.51; P < 0.001) and MP (AUC 0.85 vs 0.62; P < 0.001). […] Admission chest CT shows better performance than LUS for COVID-19 diagnosis, at varying disease prevalence. | 2020-10-22 |
| 33092065 | RT-PCR on nasopharyngeal (NPS)/oropharyngeal swabs is the gold standard for diagnosis of SARS-CoV-2 infection and viral load monitoring. […] Oral fluid (OF) is an alternate clinical sample, easy and safer to collect and could be useful for COVID-19 diagnosis, monitoring viral load and shedding. […] Simplexa™ COVID-19 Direct assays on OF have high sensitivity and specificity to detect SARS-CoV-2 RNA and provide an alternative to NPS for diagnosis and monitoring SARS-CoV-2 shedding. | 2020-10-23 |
| 33092563 | This case emphasises the added value of bronchoscopy with BAL in the diagnostic work-up in case of high clinical suspicion and negative serial NPS in patients presenting with severe symptoms. | 2020-10-23 |
| 33092816 | In conclusion, all assays exhibited excellent specificity and total antibody assays with spike protein configurations generally outperformed nucleocapsid configurations and IgG assays in terms of diagnostic sensitivity. | 2020-10-23 |
| 33092995 | Imaging is essential for the initial diagnosis and monitoring of the novel coronavirus, which emerged in Wuhan, China. | 2020-10-23 |
| 33093026 | Children with asymptomatic SARS-CoV-2 infection had lower levels of virus in their nasopharynx/oropharynx than symptomatic children, but the timing of infection relative to diagnosis likely impacted levels in asymptomatic children. […] Caution is recommended when choosing diagnostic tests for screening of asymptomatic children. | 2020-10-23 |
| 33093432 | Increased vaccination rates, even in healthy children, early diagnosis and timely antiviral treatment are needed to reduce severe complications and death. | 2020-10-23 |
| 33093684 | The results of our work provide a structural framework for the design of inhibitors as antiviral agents and/or diagnostic tests. | 2020-10-23 |
| 33093978 | Third, appropriate diagnostic studies should have been ordered at the time of the second telemedicine consultation to establish the correct diagnosis and direct treatment. | 2020-10-23 |
| 33094432 | Linear and Lasso classifiers identified 32 high-dimensional deep learning image features and 4 radiomics features associated with COVID-19 pneumonia diagnosis (P < 0.0001). […] Human expert diagnostic performance improved (increase by 16.5% and 11.6% in sensitivity and specificity, respectively) when using a combined deep learning-radiomics model. […] We uncover specific deep learning and radiomics features to add insight into interpretability of machine learning algorithms and compare deep learning and radiomics models for COVID-19 pneumonia that might serve to augment human diagnostic performance. | 2020-10-23 |
| 33095171 | The coronavirus SARS-CoV-2 disease (COVID-19) pandemic affects availability and performance of neurophysiological diagnostic methods, including EEG. | 2020-10-23 |
| 33095209 | The implementation of diagnostic tests among ambulatory patients could improve the occupational safety among outpatient care personnel. […] Out of all available COVID-19 diagnostic methods, rapid serological assays seemed to be a method of choice in outpatient medical care. | 2020-10-23 |
| 33095432 | The questionnaire was administered to 185 patients in a period of > 30 - < 60 days after diagnosis of COVID-19; responses were recorded in an online Excel spreadsheet. […] The questionnaire was composed of three sections: (1) demographic information; (2) presence and characteristics of tinnitus and dizziness after COVID-19 diagnosis; (3) possible association with migraine. […] Thirty-four patients (18.4%) reported equilibrium disorders after COVID-19 diagnosis. | 2020-10-23 |
| 33095454 | Here, we explored 61,485 sequences of the nucleocapsid (N) protein, a potent diagnostic and prophylactic target, for identifying the mutations to review their roles in real-time polymerase chain reaction based diagnosis and observe consequent impacts. […] Therefore, continuous monitoring is required for tracing the ongoing evolution of the SARS-CoV-2 N protein in prophylactic and diagnostic interventions. | 2020-10-23 |
| 33095653 | In our patient, the acute symptoms of vertigo and tinnitus coincided with the diagnosis of COVID-19. | 2020-10-23 |
| 33096033 | The median duration from diagnosis to the last positive test was 20 days (IQR, 16-31 days), and the longest duration was 40 days. | 2020-10-23 |
| 33096742 | Thus, although not highly suitable for early diagnosis, antibody-based methods can be utilized to detect past infections hidden in the population, including asymptomatic ones. […] The development and integration of such immunoglobulin-based tests can transform the pandemic diagnosis by moving the same out of the clinics and laboratories into community testing sites and homes. | 2020-10-24 |
| 33097297 | Chest computed tomography (CT) scan is frequently used in the diagnosis of COVID-19 pneumonia. | 2020-10-24 |
| 33097467 | Access to diagnosis and treatments for auditory disorders and related pathologies has regressed in France during the COVID-19 pandemic, posing a risk to the patient’s chance of recovery. […] Video otoscopy solutions allow for the teletransmission of images compatible with a high-quality diagnosis, either by connecting via internet to a tele-health platform or using a smartphone or a tablet with an iOS or Android operating system. | 2020-10-24 |
| 33097933 | We studied 324 consecutive patients admitted to our Emergency Department with a confirmed diagnosis of SARS-CoV-2 infection. | 2020-10-24 |
| 33098040 | The need and adoption of away-from-clinic sampling techniques has become critical to maintain patient safety during the current COVID-19 pandemic. | 2020-10-24 |
| 33098200 | Median age at diagnosis was 61 years (interquartile range [IQR]: 52-70), and 66% were male. | 2020-10-24 |
| 33098286 | The RT-LAMP would be valuable for clinical diagnosis and epidemiological surveillance of SARS-CoV-2 infection in resource-limited areas as it does not require the use of sophisticated and costly equipment. | 2020-10-24 |
| 33098398 | In this article, we reviewed and compared some of COVID-19 and pregnancy guidelines; this can be useful for pregnant women including those with a history of infertility specially those undergone assisted reproductive techniques (ART). | 2020-10-24 |
| 33098427 | Rapid and extraction-free detection of SARS-CoV-2 from saliva by colorimetric RT-LAMP is a simple, sensitive, and cost-effective approach with broad potential to expand diagnostic testing for the virus causing COVID-19. | 2020-10-24 |
| 33098478 | In this retrospective IRB-approved study, we identified COVID-19 patients who had a standard-of-care contrast-enhanced abdominal CT scan within 5 days of their COVID-19 diagnosis at our institution (training set; n = 45, mean age 65 years, M/F 23/22) and at a second institution (validation set; n = 41, mean age 61 years, M/F 22/19). […] This model showed excellent diagnostic performance for prediction of AKI in the training set (AUC = 0.89, P < 0.001) and good performance in the validation set (AUC 0.78, P = 0.030). | 2020-10-24 |
| 33098540 | This together with raised median Factor VIII levels of 262.5%, hyperfibrinogenemia (median fibrinogen levels 7.5 g/L), increased median von Willebrand factor antigen levels 320% and elevated median D-dimer levels 1.7 μg/dl support the diagnosis of COVID-19 associated coagulopathy. | 2020-10-24 |
| 33098641 | Flow cytometry revealed the clonality of the lymphocytes confirming the diagnosis of CLL. | 2020-10-24 |
| 33098956 | Among SARS-CoV-2(+) patients, pneumonia was the main clinical diagnosis (6/7) and bronchospasm was absent. | 2020-10-25 |
| 33098994 | Overall, 86 subjects (51.8%) had confirmed SARS-CoV-2 diagnosis by RT-PCR testing on nasopharyngeal swab specimen, and 60 (36.2%) had a clinical suspicious of COVID-19. | 2020-10-25 |
| 33099229 | With the current COVID-19 outbreak, otolaryngologists are most exposed to the risk of infection due to the nature of the specialty.This is why they are required to find safer diagnostic alternatives minimizing aerosol-generating procedures. […] Although TLUSG could undoubtedly not replace laringoscopy, it represents a noninvasive and useful diagnostic tool for otolaryngologists especially during covid-19 pandemic.Data collected about its high sensitivity and specificity suggest that TLUSG could be a reliable method to screen vocal fold paralysis without performing aerosol-generating procedures, thus providing clear visualization of laryngeal real-time movements, even in non-compliant or high-risk infection patients. | 2020-10-25 |
| 33099339 | The demographic profile, diagnosis, surgery performed, type of surgery (routine/emergency, cranial/spinal and major/minor) in these two groups were compared. | 2020-10-25 |
| 33099793 | This study investigated the contribution of life changes due to the coronavirus to emotional distress in individuals with a diagnosis of chronic central sensitization pain and tested whether the associations between level of pain and sensitization were independent of or mediated by emotional distress. | 2020-10-25 |
| 33100183 | ED visits and hospital admissions were recorded, with diagnoses assessed by the Diagnosis Related Groups method. […] COVID-19 diagnosis and deaths were identified from the patients’ registries, and outcomes assessed until June 1st. […] Overall, 277 (1.1%) patients had confirmed COVID-19 diagnosis, and 160 (0.7%) died, 9 with COVID-19. | 2020-10-26 |
| 33100266 | and (2) What measures can be suggested to improve sleep health until proper diagnosis and treatment become safe and available again? […] If OSA is suspected, there are a range of behavioral techniques which we recommend to improve symptoms. | 2020-10-26 |
| 33100439 | Several diagnostic techniques have been developed to detect COVID-19 in this prevailing pandemic period. […] The origin, structure, current diagnostic techniques, such as molecular assays based on oligonucleotides, immunoassay-based detection, nanomaterial-based biosensing, and distinctive sample based detection are also discussed. […] Furthermore, our review highlights the admissible treatment strategies for COVID-19 and future perspectives on the development of biosensing techniques and vaccines for the diagnosis and prevention of the disease, respectively. | 2020-10-26 |
| 33100482 | To facilitate the process of diagnosis of pneumonia, we developed a deep learning framework for a binary classification task that classifies chest X-ray images into normal and pneumonia based on our proposed CGNet. | 2020-10-26 |
| 33100604 | Most of the nations with deplorable health conditions lack rapid COVID-19diagnostic test due to limited testing kits and laboratories. | 2020-10-26 |
| 33100614 | This is necessary both at the individual level, to inform diagnosis, treatment and contract tracing, as well as at the population level to inform policies to control spread of the infection. […] We describe efforts to validate these testing methods clinically and the potential advantages of the combinatorial pooling method named Tapestry Pooling that relies on compressed sensing techniques. | 2020-10-26 |
| 33100645 | Echocardiography, computed tomography scans, and biochemical investigations supported a diagnosis of peripartum cardiomyopathy. | 2020-10-26 |
| 33100648 | Simulation and memory aids should be used to familiarize team members with roles and techniques of management while in PPE. | 2020-10-26 |
| 33100656 | However, patients with oral cancer, being a semi-emergency, may also present for diagnostic and therapeutic procedures. | 2020-10-26 |
| 33100658 | Due to various limitations of diagnostic tests available, all patients can be treated as COVID-19 positive and necessary precautions are suggested to limit the transmission. | 2020-10-26 |
| 33100738 | Early recognition of abdominal symptoms, diagnosis of pathology, and timely surgical intervention may definitely improve outcome. | 2020-10-26 |
| 33100739 | However, it is currently unclear whether the use of CT thorax is a sensitive and specific diagnostic test. […] The objective of this study was to find out whether CT thorax is a reliable and accurate test in the diagnosis of COVID-19 compared to RT-PCR. […] CT thorax was normal in 130 patients, out of which 29 patients were found to have COVID-19 diagnosis after swab test. […] CT scan was found to be a reliable tool in the diagnosis of COVID-19. […] However, over-reliance on CT scan which also has a high false positive rate for diagnosis of COVID-19 infections can lead to overtreatment, overuse of resources and delays in decision-making process. | 2020-10-26 |
| 33100897 | It is not easy to process data and get the required information in real time using central processing techniques when data get very large in size. | 2020-10-26 |
| 33101037 | According to the traditional Chinese medicine treatment plan in the National COVID-19 Diagnosis and Treatment Plan (Trial Seventh Edition) of the National Health Commission, Chinese patent medicines or prescriptions rich in aromatic Chinese herbs are selected for prevention and treatment during the period of medical observation, clinical treatment, and recovery of confirmed COVID-19 patients. | 2020-10-26 |
| 33101092 | An online survey was generated, comprising of a sociodemographic section, Internet Addiction Diagnostic Questionnaire (KDAI), Symptoms Checklist-90, and Pittsburgh Sleep Quality Index. | 2020-10-26 |
| 33101157 | In order to respond it, cluster analysis techniques (Data Mining) have been used to classify people taking surveys into quotient sets (cluster). | 2020-10-26 |
| 33101314 | These suggestions reflect previous attempts of classifying ARDS into different phenotypes that might overall facilitate ARDS diagnosis and treatment. | 2020-10-26 |
| 33101547 | In the current COVID-19 pandemic, disease diagnosis is essential for optimal management and timely isolation of infected cases in order to prevent further spread. | 2020-10-26 |
| 33101672 | Since both viruses carry similar patient presentations and target similar patient populations, the ability of physicians to make a clinical diagnosis of influenza without testing is impaired. […] Obtaining the correct diagnosis for a patient presenting with a viral illness is paramount for determining the best course of treatment, particularly since the treatment for influenza has not been shown to be effective in treating COVID-19 patients. […] Another diagnosis that must be kept in mind is the possibility of co-infection with both influenza and COVID-19. | 2020-10-26 |
| 33101684 | Knowledge of lung ultrasound characteristics of coronavirus disease 2019 pneumonia might be useful for early diagnosis and clinical monitoring of patients, and lung ultrasound can help to control the spread of infection in healthcare settings. […] Lung ultrasound is useful for early diagnosis and evaluation of the severity of coronavirus disease 2019 pneumonia and for monitoring its progress over the course of the disease. | 2020-10-26 |
| 33101694 | This review addresses several issues in relation to manifestations of the body’s vital organs along with potential diagnostic blood factors in SARS-CoV-2 infection. | 2020-10-26 |
| 33101802 | Many tests have been developed including polymerase chain reaction (PCR) of the virus and rapid diagnostic testing in patients based on IgM/IgG serology. | 2020-10-26 |
| 33101806 | Three patients with diagnosis of SARS-CoV-2 pneumonia admitted to the ICU developed subcutaneous emphysema during the hospital admission. | 2020-10-26 |
| 33101821 | With no history of IV drug use history, negative transthoracic echocardiography, lack of immunocompromising condition, and blood cultures with gram-negative rods, IE became less likely of a diagnosis. […] Establishing the diagnosis of IE proved to be exceptionally complicated, especially in the setting of a COVID-19 pandemic. […] IE continues to be a clinical challenge for physicians, especially in the emergency department, due to the lack of diagnostic criteria such as positive blood cultures or vegetations visualized on echocardiographic studies. […] Diagnosis is more straightforward when patients present with obvious risk factors, but, in many cases, such as this one, those risk factors may be absent. | 2020-10-26 |
| 33102170 | Although real-time polymerase chain reaction (RT-PCR) is the current diagnostic method, challenges for low- and middle-income countries (LMICs) necessitate cheaper, higher-throughput, reliable rapid diagnostic tests (RDTs). | 2020-10-26 |
| 33102270 | Recently coronavirus outbreak which started in Wuhan, China, has caused international concern that has affected more than 29 lakh people worldwide and with no vaccine or specific antiviral drugs present as well as oblivious testing of carriers who are generally asymptomatic, the use of general health intervention techniques are failing to comply. […] In this review, we try to put forward all the relevant studies which have been published by the end of March 2020 so as to summarize the natural history, diagnosis as well as treatment strategies for eradicating COVID-19, which will help in managing this pandemic. | 2020-10-26 |
| 33102667 | These data can be further processed with various statistical techniques such as Two-way, ANOVA, MANOVA, or Cluster Analysis following the intended in-depth analysis needs. | 2020-10-26 |
| 33102678 | Besides overloading of hospital, capacity for molecular diagnosis of SARS-CoV-2 by the Ministry of Public Health was quickly overwhelmed. […] In this context, emergency authorization for SARS-CoV-2 RT-qPCR diagnosis was granted to other institutions, like the “Agencia de Regulación y Control para la Bioseguridad y Cuarentena de Galápagos” (ABG), that implemented “LabGal” with support of One Health Research Group from “Universidad de Las Américas” (UDLA). | 2020-10-26 |
| 33102686 | In this article, first we present a review of the emerging techniques for COVID-19 diagnosis using routine laboratory and/or clinical data. […] Then, we propose ERLX which is an ensemble learning model for COVID-19 diagnosis from routine blood tests. | 2020-10-26 |
| 33102879 | Whether gender-related disparities in the access to the diagnosis of COVID-19 may explain such a result need to be explored. | 2020-10-26 |
| 33102991 | Although these are rare events, they carry high morbidity and mortality and require prompt diagnosis and treatment. | 2020-10-26 |
| 33103060 | In this study, we aimed to present a geriatric patient with the diagnosis of COVID-19 and with contradictory results in rRT-PCR examinations in short time intervals. […] In our case, unlike the incubation period only, we encountered a negative rRT-PCR result on the 8th day after diagnosis. | 2020-10-26 |
| 33103130 | Initially many elective gastrointestinal (GI) endoscopies were cancelled to reduce the risk of infection and conserve personal protective equipment (PPE), but many endoscopy units are now faced with the dilemma of resuming endoscopy service during the pandemic as indefinitely postponing diagnostic procedures may lead to a delay in the diagnosis and treatment of malignancies. | 2020-10-26 |
| 33103295 | Patients with NMOSD or MOGAD included in the study received a confirmed or highly suspected diagnosis of COVID-19 between 1 March 2020 and 30 June 2020. | 2020-10-26 |
| 33103659 | Testing of neonates with perinatal or postnatal exposure to COVID-19 infection plays a vital role in the early diagnosis, management and institution of infection prevention measures thereby cutting off the chain of epidemic transmission. | 2020-10-26 |
| 33103715 | TeleNP is feasible in a pediatric clinical population ranging to begin the process of differential diagnosis and treatment planning. | 2020-10-26 |
| 33104186 | In this article, the editors of Clinical Infectious Diseases review some of the most important lessons they have learned about the epidemiology, clinical features, diagnosis, treatment and prevention of SARS-CoV-2 infection and identify essential questions about COVID-19 that remain to be answered. | 2020-10-26 |
| 33104776 | Droplet digital PCR (ddPCR) was used to assess the rate of false negative COVID-19 diagnostic tests. […] Low Ct values in SARS-CoV-2 diagnostic tests were associated with virus growth in cell culture. | 2020-10-26 |
| 33104780 | Epidemiological and clinical data of patients who were hospitalized with a diagnosis of COVID-19 were retrieved from a research database where patient information was recorded prospectively. […] Adult patients (≥18 years-old) hospitalized in COVID-19 wards with a diagnosis of mild or moderate COVID-19 between March 20, 2020 (when the first case was admitted to our hospital), and April 26, 2020 were included. | 2020-10-26 |
| 33105020 | The diagnosis of COVID-19 was based on clinical symptoms and molecular testing. | 2020-10-26 |
| 33105510 | Since 2017, medical students at the University of Bergen were taught PET/CT “hands-on” by viewing PET/CT cases in native format on diagnostic workstations in the hospital. […] Fiji was more difficult to use (score 3.0) than the previously used diagnostic workstations in the hospital (score 4.1; p < 0.001, paired t-test). | 2020-10-26 |
| 33105634 | In a context of limited COVID-19 testing availability, other risk factors of PIMS, e.g., older age, should be considered in the differential diagnosis of inflammatory syndromes in children. | 2020-10-27 |
| 33105757 | : There is some evidence showing that techniques such as mindfulness may help relieve burnout. | 2020-10-27 |
| 33105921 | It is estimated that there are at least 7.6 million cases of chronic hepatitis C in China, with both diagnosis and treatment rates far away to 2030 target. | 2020-10-27 |
| 33106109 | Similar techniques were used to detect the impact of concurrent COVID-19 infection on unfavorable outcomes for patients with stroke. | 2020-10-27 |
| 33106171 | Confirmed SARS-CoV-2 diagnosis (positive polymerase chain reaction). | 2020-10-27 |
| 33106364 | Diagnostic specificities determined using pre-COVID-19 samples for the Abbott IgG and Roche total antibody assays were 99.65% (95% CI, 98.72 to 99.90%) and 100.00% (95% CI, 99.32 to 100.00%), respectively, spanning claims made by each manufacturer. […] Diagnostic sensitivities increased for all three assays with increasing time since the onset of symptoms. | 2020-10-27 |
| 33106497 | HScores and 2004-HLH diagnostic criteria were assessed. | 2020-10-27 |
| 33106722 | The demand for health and medical related goods increased during this period globally, while the production using classical manufacturing techniques were effected because of the lockdowns and disruption in the transporation system. | 2020-10-27 |
| 33106778 | No increase in surgical time was observed in hand and wrist surgery or for debridement and washouts.Although the decrease in anaesthetic time is difficult to explain, this could be attributed to a reduction in combined anaesthetic techniques and possibly the effect of fear. | 2020-10-27 |
| 33106788 | “Unexplained” lymphopenia and/or an increase in C-reactive protein level should lead physicians to the diagnosis of COVID-19 and should, when possible, be followed by diagnostic testing with universal reverse transcriptase-polymerase chain reaction, as well as the reinforcement of contamination barrier measures. | 2020-10-27 |
| 33106856 | Increased interest in remote neuropsychological assessment techniques in the face of the coronavirus 2019 (COVID-19) pandemic warrants an updated review of relevant remote assessment literature. […] Tables summarizing the identified cognitive assessments, information on diagnostic accuracy, and comparisons to face-to-face cognitive assessment are included in supplementary materials. | 2020-10-27 |
| 33106939 | A serologic test can be a useful adjunctive diagnostic tool in cases where SARS-CoV-2 infection is highly suspected but the nucleic acid test is negative. | 2020-10-27 |
| 33107116 | Five RT-PCR kits assessed in this study showed acceptable analytical performance characteristics and are useful tools for the routine diagnosis of SARS-CoV-2. | 2020-10-27 |
| 33107217 | These findings led to the diagnosis of acute lympho-plasmo-histiocytic myocarditis. | 2020-10-27 |
| 33107280 | Airway clearance techniques should be administered only strictly needed and early activities must be encouraged. […] Potential physiotherapy interventions for children with COVID-19/SARS-CoV-2 consist on ventilatory management, airway clearance techniques and early activities and mobilization. | 2020-10-27 |
| 33107286 | In this study, we aimed to investigate the demographic characteristics and risk factors of patients with the diagnosis of COVID-19. | 2020-10-27 |
| 33107304 | CRISPR-Cas12a is a genome-editing system, recently also harnessed for nucleic acid detection, which is promising for the diagnosis of the SARS-CoV-2 coronavirus through the DETECTR technology. | 2020-10-27 |
| 33107558 | Laboratory testing and the measurement of appropriate biomarkers play a critical role in managing patients with coronavirus disease 2019 (COVID-19), allowing for disease diagnosis, monitoring progression, prognostication, prediction of treatment response, and risk stratification. | 2020-10-27 |
| 33107601 | We aimed to evaluate the rates of false-positive test results of three rapid diagnostic tests (RDTs) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific immunoglobulin G (IgG) and IgM detection. | 2020-10-27 |
| 33107614 | The emerging pandemic of coronavirus disease 2019 (COVID-19) has affected over 200 countries and resulted in a shortage of diagnostic resources globally. […] Rapid diagnosis of COVID-19 is vital to control the spreading of the disease, which however is challenged by limited detection capacity and low detection efficiency in many parts of the world. | 2020-10-27 |
| 33108303 | The area under the curve (AUC) and other evaluation techniques were used to assess our model. | 2020-10-27 |
| 33108374 | To accomplish this, we have used a prediction algorithm based on machine learning techniques. | 2020-10-27 |
| 33108437 | A lack of testing capabilities forces clinicians to make the crucial initial decision on the basis of clinical findings and routine diagnostic laboratory test. […] A diagnostic and triage tool for COVID-19 was designed based on the major findings in the reviewed literature. […] After a selection process, focusing on the topics “epidemiology,” “clinical characteristics,” and “diagnostic tools,” 119 out of a total amount of 1,241 publications were selected to get an overview of the growing evidence. […] The designed Early Recognition and Triage Tool enables the medical provider to use the applicable modules of the protocol for capabilities of the local setting to get the most appropriate diagnostic and triage done. | 2020-10-27 |
| 33108745 | This personal view details the experiences of a current hearing-impaired medical student in the United Kingdom, with key learning points for medical educators who may require insight into hearing loss and how to tailor their teaching techniques accordingly. | 2020-10-27 |
| 33108836 | Recognizing this additional risk amidst the ongoing pandemic serves as a caution to front-line surgical personnel to strictly adhere to personal protective equipment usage in operating rooms, to modify surgical techniques to reduce the hazard of surgical aerosol generation and COVID-19 viral exposure, and to consider it as an integral aspect of planning and adapting to the “new normal” operating practices. | 2020-10-27 |
| 33109039 | Integrative molecular dynamics simulations and thermodynamic calculations coupled with advanced postmolecular dynamics analysis techniques were employed. | 2020-10-28 |
| 33109244 | The inclusion criteria include male and female patients≥18 years of age, with a confirmed diagnosis of SARS-CoV-2 infection via polymerase chain reaction (PCR) and/or antibody test and with written informed consent to participate in this trial. | 2020-10-28 |
| 33109246 | Confirmed diagnosis of infection with SARS-CoV-2 using polymerase chain reaction and/or antibody tests. | 2020-10-28 |
| 33110186 | The CFR in HCT recipients who were not receiving immunosuppressive agents at the time of COVID-19 diagnosis was 11.5%, whereas it was 33% in HCT recipients who were receiving an immunosuppressive agent at the time of COVID-19 diagnosis. | 2020-10-28 |
| 33110587 | Set 2 contained results of 1204 assays of hospital patients (12-94 years old) with pneumonia and COVID-19 already diagnosed by molecular biological techniques in test laboratories. | 2020-10-28 |
| 33110677 | Clinical findings and diagnostic procedures in newborns, and older children are similar. | 2020-10-28 |
| 33110678 | Tracing viral mutations is also important for the development of new vaccines, antiviral drugs, and diagnostic systems. | 2020-10-28 |
| 33110725 | Based on this case, we suggest that pediatricians need to be aware of such atypical presentations and early referral to tertiary care is imperative for further early diagnosis and management. | 2020-10-28 |
| 33110938 | These approaches are expected to develop innovative and efficient health screening tools, diagnostic systems, and treatments to mitigate health risks associated with isolation and confinement on Earth and during future exploratory spaceflight missions. | 2020-10-28 |
| 33111059 | There have been several studies about the clinical features and imaging features, but very few reports have been published about pathologic findings in lung tissue, which was partly because of the lack of tissue diagnosis secondary to suddenness of the outbreak. | 2020-10-28 |
| 33111204 | Elective, non-urgent assessment may be temporarily postponed and patients are triaged to decide whether dysphagia assessment is necessary; instrumental assessment of swallowing is performed only if processing of the instruments can be guaranteed and clinical assessment has not provided enough diagnostic information for treatment prescription. | 2020-10-28 |
| 33111460 | Monthly oncological activity differences between 2019 and 2020 (screening tests, histopathological analyzes, multidisciplinary tumor board meetings (MTBMs), diagnostic announcement procedures (DAPs), and treatments were calculated in two French areas experiencing different pandemic intensity (Reims and Colmar). […] COVID-19 has had a dramatic impact in terms of screening (-86% to -100%), diagnosis (-39%), and surgical treatment (-30%). | 2020-10-28 |
| 33111514 | It is imperative that the diagnosis and treatment of patients who have a cancer that progresses rapidly, such as malignant melanoma, high-risk squamous cell carcinoma and a high risk of metastasis, are delayed. […] Diagnosis and treatment of skin cancers is a process that requires many procedures. | 2020-10-28 |
| 33111600 | Capsule endoscopy (CE) is an established modality in the diagnostic algorithm of small bowel (SB) pathology. […] The data on colon CE suggest comparable diagnostic accuracy to colonoscopy for polyp detection; however, more evidence is required in the high-risk group. […] Artificial intelligence within CE has demonstrated similar if not better diagnostic yield compared to the human with a significantly shorter reading time. | 2020-10-28 |
| 33111751 | After diagnosis in patients that returned from Italy to the São Paulo city in late February by RT-PCR, SARS-CoV-2 isolates were obtained in cell cultures and characterised by full genome sequencing, electron microscopy and in vitro replication properties. | 2020-10-28 |
| 33111813 | A male patient with flu-like symptoms and tomography and laboratory diagnosis of severe acute respiratory syndrome. […] A review and discussion about coronavirus disease 2019-related cardiac manifestations are reported, focusing on the imaging findings to make diagnosis. | 2020-10-28 |
| 33112053 | Cutaneous T-cell lymphoma (CTCL) diagnosis does not represent a predisposing factor to viral infections and most of CTCL patients have indolent disease. | 2020-10-28 |
| 33112108 | We present results on trend analysis supported by statistical techniques. | 2020-10-28 |
| 33112124 | Additionally, since some viral diseases and antiviral drugs may have a negative impact on the mother and fetus, in which case, pregnant women need special attention for the prevention, diagnosis, and treatment of COVID-19. | 2020-10-28 |
| 33112652 | The pandemic of COVID-19 presented an enormous challenge to the medical world in terms of diagnosis, treatment and health-care management as well as service organisation and provision. […] Imaging played a crucial role in the diagnosis of COVID-19-related lung disease, with plain radiography and CT being the main diagnostic modalities, with ultrasound a useful bedside imaging tool. […] The accurate and early diagnosis of the disease was not the only issue faced by Radiology Departments across the world; prevention of nosocomial infection, creating capacity with elective imaging suspension, management and protection of the workforce being few of the numerous challenges. | 2020-10-28 |
| 33112980 | These cases were categorized according to the risk stratification model as follows: RC I-confirmed SARS-CoV‑2 infection 36% (n = 9), RC II-reasonable suspected cases 32% (n = 8), RC III-differential diagnostic cases 12% (n = 3), RC IV-low probability 8% (n = 2) and RC V-no evidence 12% (n = 3). | 2020-10-28 |
| 33114053 | Data on diagnosis of infection in the general population are strategic for different applications in the public and private spheres. | 2020-10-29 |
| 33114057 | Accurate diagnosis at an early stage of infection is essential for the successful management of any contagious disease. […] The primary diagnosis of the infection is done either by the molecular technique of RT-qPCR by detecting portions of the RNA of the viral genome or through immunodiagnostic tests by detecting the viral proteins or the antibodies produced by the host. […] As the demand for the test increased rapidly many naive manufacturers entered the market with novel kits and more and more laboratories also entered the diagnostic arena making the test result more error-prone. […] In this paper, we review the techniques available for SARS-CoV-2 diagnosis and probable factors that can reduce the sensitivity and specificity of the different test methods currently in vogue. | 2020-10-29 |
| 33115325 | We measured the diagnostic accuracy of apical lung assessment alone and in combination with patient-reported symptoms and incorporate both to propose a COVID-19 era AIS algorithm. […] Apical lung assessment when used in isolation, yielded a sensitivity of 0.67, specificity of 0.93, positive predictive value of 0.19, negative predictive value of 0.99, and accuracy of 0.92 for the diagnosis of COVID-19, in patients presenting to the hospital for AIS. | 2020-10-29 |
| 33115334 | In this review, we outline the rationale for the use of blood biomarkers (BBs) for diagnosis of brain injury in COVID-19 patients, the research needed to incorporate their use into clinical practice, and the improvements in patient management and outcomes that can result. […] Food and Drug Administration for diagnosis of mild versus moderate traumatic brain injury and have identified brain injury after stroke, cardiac arrest, hypoxia, and epilepsy. […] BBs, integrated with other diagnostic tools, could enhance understanding of viral mechanisms of brain injury, predict severity of neurological deficits, guide triage of patients and assignment to appropriate medical pathways, and assess efficacy of therapeutic interventions in COVID-19 patients. | 2020-10-29 |
| 33115440 | This is especially the case for our global diagnostic strategy. […] While current laboratory-based centralized RT-qPCR will continue to serve as a gold standard diagnostic into the foreseeable future, the shortcomings of our dependence on this method have been laid bare. | 2020-10-29 |
| 33115512 | We describe a 14-month-old boy, with a previous diagnosis of propionic acidemia (PA) by expanded newborn screening, who, admitted for a suspected metabolic crisis, tested positive for SARS-CoV-2. | 2020-10-29 |
| 33115581 | In eDKA, metabolic acidosis and anion gap appear in blood gases and serum glucose in less than 200 mg/dl.This can delay diagnosis and treatment. […] We noticed that during the current pandemic, some other diagnoses can be missed or their diagnosis can be delayed. | 2020-10-29 |
| 33115679 | It also compared the diagnostic performances of upper respiratory tract (URT) and lower respiratory tract (LRT) samples for SARS-CoV-2 infection. […] Furthermore, LRT samples increased the accuracy of diagnosis of COVID-19. | 2020-10-29 |
| 33115680 | Similar symptoms and laboratory findings between dengue and coronavirus disease 2019 (COVID-19) pose a diagnostic challenge in some dengue-endemic countries in Asia. | 2020-10-29 |
| 33115681 | Several RT-qPCR kits are available for SARS-CoV-2 diagnosis and some have emergency use authorization from the US Food and Drug Administration. […] We designed a triplex RT-qPCR assay based on nCoV19 primers and probes where N1, N2, and RP are labeled with FAM, HEX, and Cy5, respectively, so only a single PCR reaction is required for each sample for SARS-CoV-2 diagnosis. […] This new triplex RT-qPCR assay based on primers and probes from the CDC protocol is highly reliable for SARS-CoV-2 diagnosis, and it could speed up detection and save reagents during the current SARS-CoV-2 testing supplies shortage. | 2020-10-29 |
| 33115823 | The field advanced from a publicly available viral genome to a commercialized globally scalable diagnostic biomarker test in less than 2 months, and first-in-human dosing with vaccines and repurposed antivirals followed shortly thereafter. […] SIGNIFICANCE STATEMENT: Faced with the unprecedented threat of the severe acute respiratory syndrome coronavirus 2 pandemic, the biomedical community collaborated to develop a globally scalable diagnostic biomarker (viral DNA) that catalyzed therapeutic development at breathtaking speeds. | 2020-10-29 |
| 33115911 | Appropriate antithrombotic measures can prevent complication of DVT such as pulmonary embolism with prompt early diagnosis and treatment. | 2020-10-29 |
| 33116056 | Six patients with the diagnosis of ocular hypertension, glaucoma suspect, or glaucoma underwent standard automated perimetry (24-2 or 10-2 SITA, Humphrey Field Analyzer) while wearing ear-loop surgical face masks. | 2020-10-29 |
| 33116089 | Now a days for early diagnosis of COVID-19 the nucleic acid based test like RT PCR (real time reverse transcription polymerase chain reaction) is most consistent and used all over the world. […] So, Molecular diagnosis of this pandemic virus especially by N and ORF gene might be helpful to reduce the spread of SARS-CoV-2 as well as early treatment for saving many lives. | 2020-10-29 |
| 33116103 | To conclude, chest CT imaging has high sensitivity for diagnosis of COVID-19, Data and analysis from our study suggests that chest CT ought to be considered for the COVID-19 as a primary diagnostic tool for early detection of COVID-19 patients where awaited RT-PCR results. | 2020-10-29 |
| 33116660 | The emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in a worldwide devastating effect with a diagnostic challenge. | 2020-10-29 |
| 33116679 | A total of 529 patients diagnosed with NCP were recruited from three hospitals and classified by four severity types during hospitalization following the standards of the Chinese Diagnosis and Treatment of Pneumonia Caused by New Coronavirus Infection (eighth version). | 2020-10-29 |
| 33116963 | In the diagnostic assessment of children with RTIs, many patients ultimately undergo imaging studies for further evaluation. | 2020-10-29 |
| 33117480 | The authors of this article aim to emphasize the diagnostic and therapeutic challenges faced while treating COVID/hemopathy patients. | 2020-10-29 |
| 33117540 | A clinical diagnosis should supplant such cases. | 2020-10-29 |
| 33117632 | The UDO Laboratory Analyses Task Force in Korea Centers for Disease Control and Prevention in April 2018, assigned unknown diseases into 5 syndromes, designed an algorithm for diagnosis, and made a panel list for diagnosis by exclusion. […] In December 2019, through TTX, individual missions, epidemiological investigations, sample treatments, diagnosis by exclusions, and next generation sequencing analysis were discussed, and a novel coronavirus was identified as the causal pathogen. | 2020-10-29 |
| 33117825 | Hence, dental professionals, with their knowledge of basic human science and sterile surgical techniques, are an invaluable resource in the COVID-19 pandemic response. | 2020-10-29 |
| 33117855 | Due to insufficient diagnostic testing in the United States, there is a need for clinical decision-making algorithms to guide testing prioritization. | 2020-10-29 |
| 33117891 | Importantly, the use of remote platforms to carry out online teaching has been especially vital in ensuring the continued training of doctors but other techniques such as telemedicine, online clinical case repositories and even virtual reality headsets are also being used to overcome these difficult circumstances. | 2020-10-29 |
| 33118037 | Baseline characteristics included socio-demographics, co-morbidity and previous drug use at the time of diagnosis, and polymerase chain reaction (PCR) testing and results. […] In the month after diagnosis, 14.8% (14.6-15.0) were hospitalized, with a greater proportion of men and older people, peaking at age 75-84 years. | 2020-10-29 |
| 33118327 | It also discusses on the evaluation of SARS-CoV-2 structural nucleocapsid protein properties via computational approaches to generate high-affinity binding probes for effective diagnosis and targeted treatment applications by specific targeting of viruses. | 2020-10-29 |
| 33118529 | Epidemiologically, there are similarities between the two viruses including asymptomatic spread, disproportionate impact on persons of color, need for rapid diagnostic testing, and lack of a cure or vaccine. | 2020-10-29 |
| 33118666 | To investigate the eosinophil cell (EC) expression in peripheral blood of patients infected with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) and its clinical significance of diagnosis and prognosis. 95 patients, whose nucleic acid test of SARS-CoV-2 was positive to make a definite diagnosis of COVID-19, were selected as the study group. […] It is suggested that ECs have certain clinical significance in the diagnosis and prognosis of COVID-19, and may be a useful index in the early warning of acute infectious diseases. | 2020-10-29 |
| 33118904 | We employed polymerase chain reaction (PCR, for symptomatic individuals) and serology (for both PCR-negative symptomatic workers and asymptomatic workers) as diagnostic tests for severe acute respiratory coronavirus virus 2 (SARS-CoV-2). […] In total, 1,081 (36.5%) presented a positive diagnostic test for SARS-CoV-2. | 2020-10-29 |
| 33119428 | COVID-19 related liver injury at the time of diagnosis of COVID-19 does not seem to be associated with a more severe course of the disease in our hospital. | 2020-10-29 |
| 33119539 | Furthermore, we asked them directly via personal messaging to rank the appearance of the first 3 symptoms they had experienced immediately before (or after) their COVID-19 diagnosis. […] Finally, we tracked their Twitter timeline to identify additional symptoms that were mentioned within ±5 days from the day of the first tweet on their COVID-19 diagnosis. | 2020-10-29 |
| 33119841 | Remote diagnosis of fractures is done successfully on an outpatient basis in many countries. | 2020-10-29 |
| 33119946 | Throughout the event, diagnostic tests function as an essential tool for understanding, mitigating, and implement strategies to curb and reduce infections. | 2020-10-29 |
| 33119960 | The use of optical techniques for viral detection has flourished in the past 15 years, providing more reliable, inexpensive, and accurate detection methods. | 2020-10-29 |
| 33120235 | We further demonstrated its clinical diagnostic efficacy by configuring PEI-CISG into a commercial AuNP-LFS detection kit for SARS-CoV-2 antibody detection. | 2020-10-29 |
| 33120327 | The AEP includes adults (age 18-60) with a first unprovoked seizure, new diagnosis of epilepsy or drug resistant focal epilepsy. | 2020-10-29 |
| 33120588 | Finally, a medical application of the suggested approximations in decision making of diagnosis of COVID-19 is illustrated. | 2020-10-30 |
| 33120625 | Parameters evaluated were age, gender, presenting complaints, final diagnosis, treatment advised, and surgical interventions. | 2020-10-30 |
| 33120626 | Subspecialty was decided based on the diagnosis. | 2020-10-30 |
| 33120643 | The advent of customized component corneal transplantation using simple cost-effective techniques will be the future trend in the years to come. | 2020-10-30 |
| 33120752 | According to the Diagnosis and Treatment Guidelines for COVID-19 (seventh version) that issued by the National Health Committee of the People’s Republic of China, patients were divided into 3 subgroups: 186 ordinary, 45 severe and 30 critical ones. […] Close monitoring of coagulation function may be helpful for early diagnosis of severe patients and guidance of treatments. | 2020-10-30 |
| 33120818 | The topic popularity of clinical symptoms and diagnosis has been steady. | 2020-10-30 |
| 33121413 | The twenty eligible articles reported 33 cases of confirmed COVID-19 diagnosis who developed an autoimmune disease after the onset of covid-19 symptoms. | 2020-10-30 |
| 33121426 | COVID-19 cases have been reported as a global threat and several studies are being conducted using various modelling techniques to evaluate patterns of disease dispersion in the upcoming weeks. | 2020-10-30 |
| 33121456 | Studies on lung cancer diagnosis and treatment during an epidemic are lacking. […] We analyzed the impact of COVID-19 on lung cancer diagnosis in Korea, where lung cancer incidence continues to rise. […] Wide-range screening and preventive measures were implemented, thus minimizing the delay in lung cancer diagnosis. | 2020-10-30 |
| 33121497 | Tocilizumab was given to 16 patients with elevated IL-6 concentration. 366 patients were defined as common cases, 411 patients as severe, and 124 patients as critical according to the Chinese guideline on diagnosis and treatment of COVID-19. […] Serum IL-6 should be included in diagnostic work-up to stratify disease severity, but the benefit of tocilizumab needs further confirmation. | 2020-10-30 |
| 33121615 | Three highly pathogenic coronaviruses have been associated with outbreaks and epidemics and have challenged clinical microbiology laboratories to quickly develop assays for diagnosis. […] With the great advance in metagenomic whole-genome sequencing directly from clinical specimens, diagnosis of novel coronaviruses could be quickly implemented into the workflow of managing cases of pneumonia of unknown cause, which will markedly affect the time of the initial characterization and accelerate the initiation of outbreak control measures. | 2020-10-30 |
| 33121625 | The entire spectrum of diagnostic testing, from reagent supply to test performance, has been a major focus during the coronavirus disease 2019 (COVID-19) pandemic. | 2020-10-30 |
| 33121887 | As a result of the COVID-19 pandemic, outpatient diagnostic imaging (DI) facilities experienced decreased operations and even unprecedented closures. | 2020-10-30 |
| 33122153 | Secondary outcomes included all-cause mortality and post-operative complications at 30-days. 500 patients underwent surgery with median age 62.5 (IQR 51-71). 65% were male, 60% had a known diagnosis of cancer and 61% of surgeries were considered complex or major. […] No patient died from COVID-19 at 30-days. 30-day all-cause mortality was 3/500 (1%). 10 (2%) patients were diagnosed with COVID-19, 4 (1%) with confirmed laboratory diagnosis and 6 (1%) with probable COVID-19. 33/500 (7%) of patients developed Clavien-Dindo grade 3 or higher complications, with 1/33 (3%) occurring in a patient with COVID-19. | 2020-10-30 |
| 33122241 | Our case further highlights the need for careful diagnosis in suspected cases of GBS associated with SARS-CoV-2 infection. | 2020-10-30 |
| 33122486 | The inclusion criteria for both registries were aged ≥18 years and a final diagnosis of acute MI (AMI) with positive troponin levels. | 2020-10-30 |
| 33122504 | These techniques are demonstrated in the accompanying video. […] The other safety measures described are simple and efficient techniques which can easily be adopted for otologic surgery using the microscope. | 2020-10-30 |
| 33122941 | Perioperative anesthesia-related mortality is significantly higher in resource-limited countries and every effort should be made to encourage the use of anesthetic techniques in these countries that are safest under the present conditions. | 2020-10-30 |
| 33123144 | Although RT-PCR remains the gold standard, it is a time-consuming procedure, paving the way for newer techniques such as serologic tests and enzyme immunoassays. | 2020-10-30 |
| 33123533 | Grounding on prior knowledge such as experimentally validated host proteins known to be viral interactors, tissue-specific gene expression data, and using network analysis techniques such as network propagation and connectivity significance, the host molecular reaction network to the viral invasion is explored and exploited to infer and prioritize candidate target genes, and finally to propose drugs to be repurposed for the treatment of COVID-19. | 2020-10-30 |
| 33123599 | Moreover, despite an initial increase for devices and training costs, teleophthalmology demonstrated a good cost-to-efficacy ratio; however, no national screening program has yet focused on DR prevention and diagnosis. | 2020-10-30 |
| 33123675 | Therefore, COVID-19 is a new differential diagnosis to bear in mind when evaluating patients with musculoskeletal symptoms and rheumatologists might play a crucial role in identifying COVID-19 cases in early phases of the illness. | 2020-10-30 |
| 33123774 | Seventy-three subjects with confirmed diagnosis of COVID-19 were investigated in this study. | 2020-10-30 |
| 33123790 | The diagnostic accuracy of chest CT and inter-observer agreement using the kappa coefficient were evaluated over the study period. […] Diagnostic accuracy was consistent over the study period, irrespective of a variable prevalence rate. […] Chest CT demonstrated high diagnostic accuracy with strong inter-observer agreement between on-call teleradiologists with varying degrees of experience and senior radiologists over the study period. | 2020-10-30 |
| 33123808 | A total of 52 women with a confirmed diagnosis of COVID-19 delivered in the participating centers during the study period. | 2020-10-30 |
| 33124612 | The diagnostic test is based on the search for viral RNA through nasopharyngeal swab. | 2020-10-30 |
| 33124797 | Bioanalytical diagnostic technologies have played a critical role in the mitigation of the COVID-19 pandemic and will continue to be foundational in the prevention of the subsequent waves of this pandemic along with future infectious disease outbreaks. […] In this Review, we aim at presenting a roadmap to the bioanalytical testing of COVID-19, with a focus on the performance metrics as well as the limitations of various techniques. […] The combination of different classes of diagnostic technologies (centralized and point-of-care and relying on multiple biomarkers) are needed for effective diagnosis, treatment selection, prognosis, patient monitoring, and epidemiological surveillance in the event of major pandemics such as COVID-19. | 2020-10-30 |
| 33124920 | Diagnosis and intervention for patients with underlying cardiovascular comorbidities is critical. | 2020-10-30 |
| 33124971 | : Hematologic laboratory parameters have always been a crucial component of diagnostic and therapeutic strategies in infectious disease. | 2020-10-30 |
| 33125422 | However, it can reliably distinguish oral swabs from swabs that were not used orally, which makes it a useful SAC for oral swab-based diagnosis. | 2020-10-30 |
| 33125439 | Together, these data shed new light on the current view of SARS-CoV-2 pathogenesis and lay the foundation for better diagnosis and treatment of COVID-19 patients. | 2020-10-30 |
| 33125498 | In this cohort, specific admission laboratory studies in concert with sociodemographic features and prior diagnosis facilitated risk stratification among individuals hospitalized for COVID-19. | 2020-10-30 |
| 33125628 | The prevention, diagnosis, and treatment of malnutrition should therefore be routinely included in the management of individuals with COVID-19. | 2020-10-30 |
| 33126149 | Serologic assays for antibody detection aid patient diagnosis and seroepidemiologic investigations. […] The BPL inactivated virus-based ELISA could detect IgG antibodies early and in a significant proportion of COVID-19 patients suggesting its potential utility as a supplement to the currently used viral RNA detection tests in patient diagnosis and contact screening algorithms. | 2020-10-30 |
| 33126177 | The opvCRISPR diagnostic results provide 100% agreement with the Centers for Disease Control and Prevention (CDC)-approved quantitative RT-PCR assay. | 2020-10-30 |
| 33126179 | For the patients included in the study (n = 4), the level of salivary IgA correlated with the time elapsed from diagnosis and with the severity of the disease. […] This IgA-LFIA immunosensor could be useful for noninvasively monitoring early immune responses to COVID-19 and for investigating the diagnostic/prognostic utility of salivary IgA in the context of large-scale screening to assess the efficacy of SARS-CoV-2 vaccines. | 2020-10-30 |
| 33126180 | The diagnosis tools available so far have been based on a) viral gene detection, b) human antibody detection, and c) viral antigen detection, among which the viral gene detection by RT-PCR has been found as the most reliable technique. | 2020-10-30 |
| 33126309 | We document the development of “suspected ward,” a ward that cared for patients with suspected COVID-19, in a large designated hospital during the COVID-19 outbreak in Wuhan City, China, and explain the suspected ward spatial layout, organization structure, diagnosis, and treatment flow chart of suspected cases. […] The key characteristics of our “suspected ward” is isolation, triage, fast diagnosis, and rapid referral. | 2020-10-31 |
| 33126730 | Many papers have been published recently that focus on developing new and facile techniques to reuse and reinforce commercially available face masks. | 2020-10-31 |
| 33126820 | Our findings may influence communication techniques of local health departments and offer a way to understand how this often-overlooked community deals with the pandemic. | 2020-10-31 |
| 33127345 | The model contains 208 standards distributed into nine criteria: leadership and strategy; prevention and infection control; management of professionals and skills; public areas; healthcare areas; areas of support for diagnosis and treatment; logistics, technology and works; communication and patient care; and information and research systems. | 2020-10-31 |
| 33127456 | We estimated the effects of having clinical encounters for various diagnostic categories in the year preceding the study period on the risk of a positive test result. […] Regardless of the cause, the reduction in the odds of being infected by SARS-CoV-2 among those with a recent diagnosis of common cold symptoms may have a role in shifting future COVD-19 infection patterns from endemic to episodic. | 2020-10-31 |
| 33127841 | Quantitative suspension array technology (qSAT) assays based on the xMAP Luminex platform overcome the limitations of rapid diagnostic tests and enzyme-linked immunosorbent assays (ELISAs) with their higher precision, dynamic range, throughput, miniaturization, cost-efficiency, and multiplexing capacity. […] We evaluated their performances using 128 prepandemic plasma samples (negative controls) and 104 plasma samples from individuals with SARS-CoV-2 diagnosis (positive controls), of whom 5 were asymptomatic, 51 had mild symptoms, and 48 were hospitalized. | 2020-10-31 |
| 33128391 | Among 114 academic institutions affiliated with OHNS residencies, 20 (17.5%) institutions provided public access to some form of guidance on PPE and 73 (64%) provided information on screening or diagnostic testing. | 2020-10-31 |
| 33128444 | In particular, there is a need to ensure that effective surveillance and diagnostic capacities are in place to monitor these and other respiratory viruses, as this will underpin decisions on the appropriate clinical management of the respective diseases. | 2020-10-31 |
| 33128509 | The objectives were to evaluate cumulative 30-day all-cause mortality, COVID-19 attributable mortality, factors predicting mortality, and time to viral negativity after initial diagnosis. | 2020-10-31 |
| 33128540 | A diagnosis of GBS was made, and he was treated successfully with IVIG. […] Early diagnosis and treatment of GBS can prevent neurological disability. | 2020-10-31 |
| 33128737 | Post-mortem ultrasonographic techniques are considered to be a safer alternative to high-risk post-mortem procedures, especially in infectious diseases. | 2020-10-31 |
| 33128859 | Triaging using telemedicine and artificial intelligence along with utilization of bedside rapid diagnostic tests to detect Covid-19 could prove helpful in this aspect. | 2020-10-31 |
| 33129039 | The same factors, age along with corticosteroids before COVID-19 diagnosis, and thoracic primary tumour site were independently associated with COVID-19 severity. […] A total of 431 (39%) patients had their systemic anticancer treatment (such as chemotherapy, targeted or immune therapy) interrupted or stopped following diagnosis of COVID-19. […] In almost 40% of patients, the systemic anticancer therapy was interrupted or stopped after COVID-19 diagnosis. | 2020-10-31 |
| 33129056 | The entire sample (100%) was admitted to surgery, diagnostic accuracy was 100%. […] Diagnostic accuracy was 85%. | 2020-10-31 |
| 33129072 | Tremendous research and commercialization efforts around the world are focused on developing novel wearable electrochemical biosensors that can noninvasively and continuously screen for biochemical markers in body fluids for the prognosis, diagnosis and management of diseases, as well as the monitoring of fitness. | 2020-10-31 |
| 33129141 | The recent global outbreak and spread of coronavirus disease (COVID-19) makes it an imperative to develop accurate and efficient diagnostic tools for the disease as medical resources are getting increasingly constrained. […] Artificial intelligence (AI)-aided tools have exhibited desirable potential; for example, chest computed tomography (CT) has been demonstrated to play a major role in the diagnosis and evaluation of COVID-19. […] However, developing a CT-based AI diagnostic system for the disease detection has faced considerable challenges, which is mainly due to the lack of adequate manually-delineated samples for training, as well as the requirement of sufficient sensitivity to subtle lesions in the early infection stages. […] In this study, we developed a dual-branch combination network (DCN) for COVID-19 diagnosis that can simultaneously achieve individual-level classification and lesion segmentation. […] An online CT-based diagnostic platform for COVID-19 derived from our proposed framework is now available. | 2020-10-31 |
| 33129363 | • Known sensitivity/allergy to hydroxychloroquine or Favipiravir • Current use of hydroxychloroquine for another indication • Prior diagnosis of retinopathy • Prior diagnosis of glucose-6-phosphate dehydrogenase (G6PD) deficiency • Major comorbidities increasing the risk of study drug including: i. | 2020-11-01 |
| 33130151 | Real-time reverse transcription-polymerase chain reaction (RT-qPCR) is considered the “gold standard” for the direct diagnosis of SARS-CoV-2 infections. […] However, routine diagnosis by RT-qPCR is a limitation for many laboratories, mainly due to the infrastructure and/or disproportionate relationship between demand and supply of inputs. […] In this context, and to increase the diagnostic coverage of SARS-CoV-2 infections, we describe an alternative, sensitive and specific one-step end-point RT-PCR for the detection of the SARS-CoV-2 E gene. […] Finally, considering specificity, analytical sensitivity and cost reduction, we believe that the RT-PCR platform described here may be a viable option for the diagnostic of SARS-CoV-2 infections in laboratories in which RT-qPCR is not available. | 2020-11-01 |
| 33130198 | Real-time quantitative PCR (qRT-PCR) is the recommended diagnostic test but a number of constraints prevent its widespread implementation, including cost. […] The sensitivity and specificity of the antigen test were 70.0% (95% confidence interval (CI): 60-79) and 92% (95% CI: 87-96), respectively, and the diagnostic accuracy was 84% (95% CI: 79-88). | 2020-11-01 |
| 33130201 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019 and quickly spread around the world, forcing global health authorities to develop protocols for its diagnosis. […] Here we report dimer formation in the N2 primers-probe set (CDC 2019-nCoV Real-Time RT-PCR) used in the diagnostic routine, and propose alternatives to reduce dimerization events. | 2020-11-01 |
| 33130435 | COVID-19 diagnosis is usually based on PCR test using radiological images, mainly chest Computed Tomography (CT) for the assessment of lung involvement by COVID-19. […] The development of COVID-19 automatic detection systems based on Natural Language Processing (NLP) techniques could provide a great help in supporting clinicians and detecting COVID-19 related disorders within radiological reports. | 2020-11-01 |
| 33130449 | Early diagnosis is important to control COVID-19 outbreaks. […] This study aimed to assess how individual and area socioeconomic position and geographical accessibility to healthcare services were associated with the time to diagnosis among symptomatic COVID-19 patients in Hong Kong. […] This study found living in public rental housing and living in an area with low education were associated with longer time to diagnosis in the first wave of infections. […] Specifically, the risk of delayed diagnosis for public rental housing residents was mitigated by the higher density of public clinics/hospitals but was slightly increased by the higher density of private medical practitioners nearby. | 2020-11-01 |
| 33130510 | As new tests and technologies advance our understanding and diagnostic capabilities of the severe acute respiratory syndrome coronavirus 2 and the coronavirus disease 2019, they must be appropriately validated to make sure test performance is following manufacturer claims. | 2020-11-01 |
| 33130550 | Primary end-points were severe disease and death in the cancer patients treated within the last 30 days before COVID-19 diagnosis. […] Chemotherapy within the last thirty days before COVID-19 diagnosis increased the risk of death in cancer patients after adjusting for confounding variables (OR: 1.85; 95% confidence interval: 1.26-2.71). | 2020-11-01 |
| 33130584 | During the global pandemic of COVID-19 accurate diagnosis of the infection by demonstrating SARS-CoV-2 viral RNA by PCR in specimens is crucial for therapeutic and preventative interventions. […] A limited diagnostic autopsy was performed after 27 days, and lung swabs confirmed presence of SARS-CoV-2. | 2020-11-01 |
| 33130587 | A previously fit and well 37-year-old male healthcare worker presented with confusion, psychotic symptoms and a suicide attempt in the context of a new COVID-19 diagnosis. | 2020-11-01 |
| 33130588 | Although his symptoms started a week prior to diagnosis, his weakness increased, warranting emergency response. | 2020-11-01 |
| 33130602 | It has been expected for a long time to replace the heterogenous techniques, occasionally utilizing household equipment with a technology providing improved patient safety and fulfilling international and recently published local FMT guidelines. | 2020-11-01 |
| 33130799 | On the other hand, Polish information is not corroborated by reliable studies, both in terms of the number and quality of diagnostic tests performed and the treatment used in individual groups infected with SARS-CoV-2 and patients. | 2020-11-01 |
| 33131360 | The diagnosis of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection relies on the detection of viral RNA by real-time reverse transcription polymerase chain reaction (rRT-PCR) performed with respiratory specimens, especially nasopharyngeal swabs. […] The use of saliva as a diagnostic specimen has numerous advantages: it is easily self-collected by the patient with almost no discomfort, it does not require specialized health care personnel for its management, and it reduces the risks for the operator. […] Conversely, the promising role of saliva in the diagnosis of SARS-CoV-2 infection is highlighted by the emergence of point-of-care technologies and, most important, point-of-need devices. | 2020-11-02 |
| 33131376 | Retrospective and prospective studies reporting clinical outcomes in cancer patients with laboratory confirmation or clinical diagnosis of COVID-19 and details of active or recent oncologic treatment were selected. | 2020-11-02 |
| 33131637 | Gastrointestinal lesions could be used as basis for early diagnosis of patients, and at the same time, controlling gastrointestinal lesions better facilitated to cut off the route of fecal-oral transmission. | 2020-11-02 |
| 33131721 | The compounds may be evaluated for their inhibitory activities using experimental techniques. | 2020-11-02 |
| 33131799 | This article aims to provide a comprehensive overview of current laboratory diagnostic methods for SARS-CoV-2, including nucleic acid testing, serology, rapid antigen detection and antibody tests, virus isolation and whole genome sequencing. […] The relative advantages and disadvantages of the different diagnostic tests are presented, as well as their value in different clinical, infection control and public health contexts. | 2020-11-02 |
| 33131800 | Isolation of the new pandemic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for diagnostic and research purposes including assessment of novel therapeutics. | 2020-11-02 |
| 33131974 | As the advancement of early diagnosis and treatment, the CFR after January 21 (or 22), 2020 is substantially decreased in COVID-19 than before (OR = 0.21; 95% CI = 0.19 to 0.24; P < .00001). | 2020-11-02 |
| 33132006 | This study identifies the areas where telephone medicine can make a valuable contribution to making diagnosis and treating orthopedic patients. | 2020-11-02 |
| 33132008 | Enrolled students were considering residencies in surgery (50%), internal medicine (40%), interventional radiology (30%), and/or diagnostic radiology (30%). | 2020-11-02 |
| 33132063 | As a consequence of the lockdown, the diagnostic and therapeutic management of paediatric chronic conditions, such as inflammatory bowel disease (IBD) has been affected. | 2020-11-02 |
| 33132066 | Later, they make recommendations on the stabilisation, diagnosis, and treatment of this syndrome. | 2020-11-02 |
| 33132155 | Starting from historic reflections, the current SARS-CoV-2 induced COVID-19 pandemic is examined from various perspectives, in terms of what it implies for the implementation of non-pharmaceutical interventions, the modeling and monitoring of the epidemic, the development of early-warning systems, the study of mortality, prevalence estimation, diagnostic and serological testing, vaccine development, and ultimately clinical trials. | 2020-11-02 |
| 33132334 | We exploratorily investigated the final diagnosis among non-COVID-19 hospitalized patients who visited the fever clinic. | 2020-11-02 |
| 33132457 | I discuss the necessity of holding the therapeutic frame with increased flexibility in light of my use of self-disclosure surrounding my COVID-19 diagnosis and recovery, and I assess the impact of this disclosure. | 2020-11-02 |
| 33132488 | Pharmacists must play their role as local actors by proposing the COVID rapid diagnostic orientation test and by collaborating in the generalisation of antigenic tests. | 2020-11-02 |
| 33132536 | The detection of COVID-19 using artificial intelligence techniques and especially deep learning will help to detect this virus in early stages which will reflect in increasing the opportunities of fast recovery of patients worldwide. […] In this research, classical data augmentation techniques along with Conditional Generative Adversarial Nets (CGAN) based on a deep transfer learning model for COVID-19 detection in chest CT scan images will be presented. | 2020-11-02 |
| 33132557 | COVID-19 patients may require transport for diagnostic or therapeutic purposes intra- or interhospital or transport from an outside hospital to a healthcare facility. | 2020-11-02 |
| 33132617 | Early diagnosis, isolation, and supportive care are necessary for the treatment of the patients. | 2020-11-02 |
| 33132628 | Early diagnosis and isolation are key to contain the rapid spread of the virus. […] This method has the translational potential of in terms of the rapid diagnostics of symptomatic and asymptomatic COVID-19 and can augment current methods available for diagnosis of SARS-CoV-2. | 2020-11-02 |
| 33132629 | These patients were assessed for demographic details, diagnosis, type of surgery, delay from injury to admission, delay from admission to surgery, postoperative hospital stay, acute infection rates, readmission rates and associated injuries. | 2020-11-02 |
| 33132739 | The time-varying parameters are written as linear combinations of basis functions and are then inferred from data using sparse identification techniques. | 2020-11-02 |
| 33132743 | We have to be ready for focusing our attention to the prompt diagnosis and potential infection control procedures of the virus in integrated water and air system. | 2020-11-02 |
| 33132795 | The gold standard for detection of an active SARS-CoV‑2 infection is the direct detection of the pathogen with nucleic acid amplification techniques. […] Thanks to modern techniques thousands of SARS-CoV‑2 sequences are already available, which show a genomic variability. | 2020-11-02 |
| 33132937 | Evidence from the last few years suggest that low-cost techniques, tailored to the dyad well-being, with increasing use of technology through friendly online platforms and application robots, can be an alternative to conventional assistance during COVID-19 Pandemic. | 2020-11-02 |
| 33133232 | This paper thoroughly summarizes interdisciplinary notions and techniques, including disease model, biochip, network pharmacology, and molecular docking technology, etc., providing a reference for researchers in the screening of drugs for COVID-19 prevention and treatment. | 2020-11-02 |
| 33133697 | With the continued spread of COVID-19 across the world, rapid diagnostic tools, readily available respurposable drugs, and prompt containment measures to control the SARS-CoV-2 infection are of paramount importance. […] Examples of recent advances in diagnostic tests are CRISPR technology, IgG assay, spike protein detection, and use of artificial intelligence. […] An improved understanding of the advances in diagnostic tools, treatments, vaccines, and control measures for COVID-19 can provide references for further research and aid better containment strategies. | 2020-11-02 |
| 33133702 | Timely diagnosis is imperative for their prognosis and recovery. […] Furthermore, timely diagnosis can be made to aid in appropriate management with the help of bedside TTE and ECG in cases where CTPA is not feasible secondary to the patient’s hemodynamic instability. | 2020-11-02 |
| 33133825 | The diagnosis of COVID-19 was confirmed. | 2020-11-02 |
| 33133870 | Our case was a diagnostic dilemma as the literature review mentioned that cardiovascular manifestations are mostly reported in symptomatic and critically ill patients of COVID-19. | 2020-11-02 |
| 33133990 | To date, no safety guidelines are available for safe reconstructive microsurgical procedures in high-risk operations/known COVID-19 patients-particularly, to address operations risk and COVID-19 status of the patients, who would operate, how many should be involved, how to equip the surgeons for the procedure, when to operate as the procedure unfolds, how to adapt surgical techniques to reduce exposure risk, and can advanced technology be used to minimize exposure. | 2020-11-02 |
| 33134033 | While a great deal of literature has been published recently on the viral kinetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and diagnostic testing performance for coronavirus disease 2019 (COVID-19) in the general population, a relative paucity of information has come to light regarding implications of COVID-19 diagnostics for solid organ transplantation. […] This review examines the current state of knowledge regarding the two principal diagnostic testing strategies for SARS-CoV-2 infection, polymerase chain reaction (PCR)-based testing and serology, and discusses COVID-19 diagnostic implications for solid organ transplantation. […] Accumulating evidence regarding diagnostic fidelity and transmissibility of SARS-CoV-2 in immunocompromised patients will continue to inform optimal practices surrounding solid organ transplantation during the COVID-19 pandemic. | 2020-11-02 |
| 33134154 | One should be vigilant and versatile in surgical techniques in order to serve the needy and save the saviours simultaneously. | 2020-11-02 |
| 33134214 | The all proposed models were able to perform binary classification with the accuracy more than 90.0% for COVID-19 diagnosis. | 2020-11-02 |
| 33134308 | As in other endemic or pandemic phenomena, the issues mostly covered by scientific and media attention are related to the diagnostic and therapeutic approach of COVID-19. | 2020-11-02 |
| 33134384 | CT scanning plays an important role in the diagnosis and evaluation of COVID-19 in asymptomatic patients or those with initially negative RT-PCR results. | 2020-11-02 |
| 33134554 | As a result, diagnostic services are stretched to their limit, and there is a clear need for the provision of additional diagnostic capacity. […] Here, we describe the process of developing a SARS-Cov2 diagnostic workflow in a conventional academic Containment Level 2 laboratory. […] This was achieved under challenging circumstances through the collaborative efforts of scientists, clinical staff, and diagnostic staff to mitigate to the ongoing crisis. | 2020-11-03 |
| 33134563 | However, interactions with a child aren’t always straightforward, particularly for trainees unfamiliar with certain communication techniques, which are important to use at a time when when the wearing of face masks is commonplace. | 2020-11-02 |
| 33134740 | The advancement in clinical diagnosis techniques like Real-Time PCR (RT-PCR), immunological, microscopy, and geographic information system (GIS) mapping technology helped in tacking the rapid diagnosis and tracking viral infection in a short period. | 2020-11-02 |
| 33134745 | The popularity of these diagnostic platforms is constantly increasing in healthcare facilities, particularly those facing limited budgets and time, as well as in household use for individual health monitoring. […] The attractiveness of these portable diagnostic tools is associated primarily with their high analytical sensitivity and specificity, as well as with the easy visual readout of results. […] The latest innovations are aimed at improving the analytical performance of LFIA platforms for the diagnosis of bacterial and viral infections, including COVID-19. | 2020-11-02 |
| 33134843 | Application of a weighted C19 rule yielded likelihood ratios for COVID-19 diagnosis for varying scores ranging from LR 15.0 for 3 points to LR 0.1 for - 1 point. […] Using a Bayesian diagnostic approach, combining community prevalence with the evidence-based C19 rule to adjust pretest probability, clinicians can apply a point of care test with limited sensitivity across a range of clinical scenarios to differentiate COVID-19 infection from influenza and respiratory viral infection. | 2020-11-02 |
| 33134902 | Point-of-care tests not requiring laboratory- support will speed diagnosis and protect health-care staff. […] Differentiation of patients with definite diagnosis (25 and 65) of COVID-19 from non-COVID-19 was possible with 80% and 81.5% accuracy in Edinburgh and Dortmund respectively (sensitivity/specificity 82.4%/75%; area-under-the-receiver- operator-characteristic [AUROC] 0.87 95% CI 0.67 to 1) and Dortmund (sensitivity / specificity 90%/80%; AUROC 0.91 95% CI 0.87 to 1). […] Development and validation of this approach may allow rapid diagnosis of COVID-19 in the coming endemic flu seasons. | 2020-11-02 |
| 33134953 | We performed metabolomics profiling of critically ill coronavirus disease 2019 patients to understand better the underlying pathologic processes and pathways, and to identify potential diagnostic/prognostic biomarkers. | 2020-11-02 |
| 33134956 | The most common interventions were diagnostic test interpretation, ventilator management, and sedation change. | 2020-11-02 |
| 33135083 | The correspondence between the results from rapid testing and CLIA, when available, was evaluated. 97 subjects underwent qPCR for SARS-CoV-2 through nasal swab, which resulted positive in 40/43 (93.0%) of symptomatic patients, 2/40 (5%) of asymptomatic HCW, in no subjects with suspected COVID- 19 (clinical and radiological findings) then excluded by repeated nasal swabs and alternative diagnosis (COVID-19-negative patients, CNPs), and in 6/6 (100%) of patients with confirmed diagnosis and negative follow-up nasal swabs (COVID-19-recovered patients, CRPs). […] The test may gain particular relevance in shortening the time needed to refer patients to a COVID or non-COVID Hospital area and to achieve diagnosis in patients with persistently negative nasal swabs. | 2020-11-02 |
| 33135085 | The purpose of this paper is to summarize the current literature in order to elucidate the potential role of tear and conjunctival sampling to detect SARS-CoV-2 for the diagnosis of COVID-19 and to monitor patients during follow-up. | 2020-11-02 |
| 33135665 | Chest CT imaging is an important component in the diagnosis, staging, disease progression and follow-up of patients with COVID-19. | 2020-11-02 |
| 33135801 | This study aims to determine the clinical importance of platelet count and platelet indices in the differentiation of COVID-19 from influenza and the value of these parameters in the differential diagnosis of COVID-19. […] In the diagnosis of COVID-19, the platelet count and platelet indices are easily accessible, inexpensive, and important parameters in terms of differential diagnosis and can help in the differentiation of COVID-19 from influenza during seasonal outbreaks of the latter. | 2020-11-02 |
| 33135851 | Administrative data provided by 67 German Helios hospitals were examined for patients with a main discharge diagnosis of HF using ICD codes. | 2020-11-02 |
| 33135928 | This article summarises the epidemiology and potential options for treating COVID-19 to give a foundation for future studies of the diagnosis, treatment and prevention of this deadly disease. | 2020-11-02 |
| 33136068 | In this study, we selected 74 clinical samples from 43 recovering inpatients for qPCR and Droplet Digital PCR (ddPCR) synchronous blind detection, and established a cutoff value for ddPCR diagnosis of COVID-19. […] These results indicate that ddPCR could significantly improve the accuracy of COVID-19 diagnosis, especially for discharged patients with a low viral load, and help to reduce misdiagnosis during recovery. | 2020-11-02 |
| 33136473 | In this study, state-of-the-art techniques have been used for predicting the potential candidates for diagnostics and therapeutics. | 2020-11-02 |
| 33136555 | The diagnosis is usually performed by RT-PCR or CT chest scan. […] To assess the diagnostic performance of LUS, we performed LUS using a portable device and adapting a protocol already used in Acute Respiratory Syndrome. […] We used the score obtained with the index we created to assess for LUS diagnostic performance as compared to lung CT chest scan and to predict for oxygen requirements. […] This is the first report on the diagnostic performance of LUS as compared to CT chest scan for the diagnosis of COVID-19 pneumonia and assessments of oxygen requirements by LUS. | 2020-11-02 |
| 33136662 | Technological advancements in video conferencing and the abundance of readily available wearable devices have allowed cardiologists to establish a preliminary diagnosis and set forth a treatment plan. | 2020-11-02 |
| 33136811 | All patients with an initial diagnosis of ACS were included in the analysis, and further stratified into ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI)/unstable angina. | 2020-11-02 |
| 33137571 | Neurophysiological studies are essential in the diagnosis of these patients. | 2020-11-02 |
| 33138195 | Taken together, our data reveal the presence of neutrophils and macrophage cluster-1 as the main immune cell subsets associated with severe COVID-19 and identify their inflammatory and chemotactic gene signatures, also partially reflected systemically in the circulation, for possible diagnostic and therapeutic interventions. | 2020-11-03 |
| 33138634 | We aim to compare diagnostic performance and inter-/intra-observer among chest radiologists in the interpretation of RSNA and CO-RADS reporting systems and assess clinician preference. […] Diagnostic accuracy of both reporting systems was calculated. 60 clinicians participated in a survey to assess end-user preference of the reporting systems. | 2020-11-03 |
| 33138652 | Owing to the rapid outbreak of COVID-19 worldwide, health authorities focused on discovery of effective prevention and treatment techniques for this novel virus. […] This review aims to provide recently presented techniques and protocols for efficient treatment of COVID-19 and investigate its morphology and treatment/prevention approaches, among which usage of antiviral drugs, anti-malarial drugs, corticosteroids, and traditional medicines, biotechnological drugs (e.g. combination of HCQ and azithromycin, remdesivir, interferons, novaferon, interferon-alpha-1b, thymosin, and monoclonal antibodies) can be mentioned. | 2020-11-03 |
| 33138658 | This work prospectively evaluated data from 316 patients who were admitted with a diagnosis of COVID-19 pneumonia. | 2020-11-03 |
| 33138692 | The significant diagnostic predictors of asymptomatic carriers of COVID-19 included the blood cell, cytokine, and T lymphocyte subset levels. | 2020-11-03 |
| 33138722 | Both open and percutaneous techniques were reported. | 2020-11-03 |
| 33138810 | The survey collected data on knowledge of COVID-19 regarding the mode of transmission, symptoms, diagnosis, treatment, protection, and dental treatment precautions as well as participants’ background variables. […] The mean (SD) knowledge percent score was 73.2 (11.2) %, and the score of knowledge of symptoms was significantly lower than the score of knowledge of diagnostic methods (53.1 and 85.4%, P < 0.0001). […] Dental academics had poorer knowledge of COVID-19 symptoms than of COVID-19 diagnostic methods. | 2020-11-03 |
| 33138836 | While the detection of SARS-CoV-2 viral load in respiratory specimens is commonly used to diagnose COVID-19, detecting SARS-CoV-2 RNA in plasma or serum should not lose sight and it could be considered as an alternative diagnostic approach. | 2020-11-03 |
| 33138848 | Inclusion criteria - Age: 18-85 years old - Clinical diagnosis of Covid-19 infection - Clinical signs have been present for less than 8 days - Virological confirmation - Understanding and acceptance of the trial - Written agreement to participate in the trial Exclusion criteria - Pregnancy, breastfeeding, inability to comply with protocol, lack of written agreement - Patients using mouthwash on a regular basis (more than once a week) - Patient at risk of infectious endocarditis - Patients unable to answer questions - Uncooperative patient The clinical trial is being conducted with the collaboration of three French hospital centers: Hospital Center Emile Roux (Le Puy en Velay, France), Clinic of the Protestant Infirmary (Lyon, France) and Intercommunal Hospital Center (Mont de Marsan, France). | 2020-11-03 |
| 33138853 | Although rare, it is important to be mindful of this side effect because the diagnosis is often delayed, and the disease has the potential to be life-threatening. […] Four weeks prior, she had been initiated on hydroxychloroquine for a presumed diagnosis of cutaneous sarcoidosis. | 2020-11-03 |
| 33138856 | Therefore, the introduction of serological tests for determination of IgM and IgG antibodies has become the main diagnostic tool, useful for tracking the spread of the virus and for consequently allowing its containment. | 2020-11-03 |
| 33138936 | Patients aged 65 years and older hospitalized for a diagnosis of COVID-19. | 2020-11-03 |
| 33138985 | Differences in distress trends were examined by age, sex, race/ethnicity, and household income and by the presence of a pre-existing mental health diagnosis. | 2020-11-03 |
| 33139015 | Rapid and accurate laboratory diagnosis of active COVID-19 infection is one of the cornerstones of pandemic control. […] In this mini-review, we will discuss the difference in diagnostic performance for different upper and lower respiratory tract specimens, and the role of blood and fecal specimens. […] We will analyze the performance characteristics of laboratory testing techniques of nucleic acid amplification tests, antigen detection tests, antibody detection tests, and point-of-care tests. | 2020-11-03 |
| 33139151 | Dysosmia and/or dysgeusia are common symptoms and clues for the diagnosis of COVID-19, particularly in the early stage of the disease. […] Physicians should be alerted to these symptoms to make timely diagnosis and management for COVID-19 to limit spread. | 2020-11-03 |
| 33139419 | Commercial EIAs with high diagnostic accuracy to detect SARS-CoV-2 antibodies did not necessarily have high diagnostic accuracy to detect high nAb titers. | 2020-11-03 |
| 33139423 | As the pandemic continues, it will be important for diagnostic laboratories to adopt a flexible and streamlined approach towards maintaining adequate supply chain for testing reagents and materials. | 2020-11-03 |
| 33139827 | This essay reviews evidence of transformation in the realm of hypertension management, namely diagnosis, lifestyle changes, therapeutics and prevention of hypertension at both individual and population levels, and presents an extrapolation of how this transformation might shape the next decade. | 2020-11-03 |
| 33139998 | Although CT is not the gold standard for the diagnosis of COVID-19, it nonetheless is a convenient and fast method, and its application can be deployed in community hospitals. […] Furthermore, CT can be used to render a suggestive diagnosis and evaluate the severity as well as the effects of therapeutic interventions for typical cases of COVID-19. | 2020-11-03 |
| 33140086 | Understanding the longitudinal trajectory of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies is crucial for diagnosis of prior infection and predicting future immunity. […] One widely used commercial platform that had an initial sensitivity of >95% declined to 71% at 81-100 days after diagnosis. | 2020-11-03 |
| 33140176 | Blood cultures collected at admission showed a diagnostic yield of 4.2%. | 2020-11-03 |
| 33140943 | Numerous studies have shown that loss of smell is a serious symptom that requires careful differential diagnosis. | 2020-11-03 |
| 33141164 | Age- adjusted diagnosis rates were significantly associated with the proportion of Latino/as, individuals living below the poverty line, population, and household density. | 2020-11-03 |
| 33141520 | While the findings are not entirely surprising, the report does stand out from all others by a well-defined context-of-use, and, what is more, by presenting an already initiated validation study that may, if successful, result in immediate implementation of this proteomics-based diagnostic test. | 2020-11-03 |
| 33141813 | Several studies have been proposed and started since then, mainly covering prevention, diagnosis, management, and treatment. | 2020-11-03 |
| 33141867 | This was a retrospective review using electronic records and laboratory data of adult patients admitted to the four Manchester University Foundation Trust Hospitals between March 10 and April 30 2020 with a diagnosis of COVID-19. […] There were 1032 patients included in the study of whom 210 (20.3%) had AKI in association with the diagnosis of COVID-19. | 2020-11-03 |
| 33141933 | Data were evaluated of pregnant women who died following a laboratory diagnosis of COVID-19. | 2020-11-03 |
| 33142250 | Critically, E-negative, N2-positive results were observed in 8 symptomatic patients with a new diagnosis of COVID-19. […] Thus, though concerns remain about extended SARS-CoV-2 RT-PCR positivity in some patients, the ability of clinical laboratories to detect patients with high Ct values (including E-negative, N2-positive results) is vital for retaining maximal sensitivity for diagnostic purposes. | 2020-11-03 |
| 33143519 | The sample consisted exclusively of inpatients, and all patients were enrolled in the study regardless of their specific diagnosis or treatment schemes. 4 out of 23 patients (17.4%) had experienced adverse effects, two of which had mild hepatic enzyme elevation and one had mild sinus bradycardia. | 2020-11-04 |
| 33143815 | The purpose of this report was to examine the current evidence that supports the etiopathogenesis of COVID-19 in children and the relationship of COVID-19 with KD and MIS-C as a basis for a better understanding of the clinical course, diagnosis, and management of these clinically perplexing conditions. | 2020-11-04 |
| 33143821 | Specific biochemical markers, particularly serum ferritin, may help in diagnosis. | 2020-11-04 |
| 33144491 | The total number of first-time visits between March-May 2020 was reduced by 18%, probably due to delays in diagnosis and histological tests as well as the temporary closure of the operating rooms. | 2020-11-04 |
| 33144494 | Unfortunately, despite aggressive treatment after the diagnosis of COVID-19, the patient died quickly. | 2020-11-04 |
| 33144862 | We report a review of similar cases involving this diagnostic mimicker in the literature. | 2020-11-04 |
| 33144890 | The gold standard for detection of an active SARS-CoV‑2 infection is the direct detection of the pathogen with nucleic acid amplification techniques. […] Thanks to modern techniques thousands of SARS-CoV‑2 sequences are already available, which show a genomic variability. | 2020-11-04 |
| 33144892 | Big Data, as well as Big Data Analytics techniques, have been addressed in this context with the possibility of predicting, mapping, tracking, monitoring, and raising awareness about these epidemics and pandemics. […] The types and sources of data used in cases of previous epidemics and pandemics were identified, as well as techniques for treating these data. […] The most common techniques for analyzing these data involve the use of statistics, such as correlation and regression, combined with other techniques. | 2020-11-04 |
| 33145063 | Moreover, fibrosis-like stripes may be a sign of atelectasis of sub-segment lung tissue of COVID-19 and may be a specific sign for the diagnosis of COVID-19. | 2020-11-04 |
| 33145146 | Comprehensive diagnostic tests should be performed to determine disease severity, phase of illness, and identify other comorbidities in transplant recipients diagnosed with COVID-19. | 2020-11-04 |
| 33145293 | Though chest computed tomography (CT) and digital radiography (DR) is important in the diagnosis and treatment of COVID-19, for patients with COVID-19 who may need magnetic resonance imaging (MRI) due to other complications, we proposed the MRI procedures for patients and medical staff to reduce the risk of infection between them. | 2020-11-04 |
| 33145303 | Our results indicated that young patients, with a mild diagnosis of COVID-19 are more likely to display RP status after discharge. | 2020-11-04 |
| 33145313 | Radiological studies have an important role in the diagnosis and follow up of many infectious diseases. […] With current pandemic of Coronavirus disease 2019 (COVID-19) though the molecular analysis with reverse transcriptase polymerase chain reaction (RT-PCR) remains the cornerstone of diagnosis, the critical role of chest imaging including CT scan and baseline X-ray became apparent early in the course due to concern for less than optimal sensitivity of PCR testing. […] Delay in molecular diagnosis due to a shortage of testing kits and laboratory personnel also makes imaging an important modality in early diagnosis for appropriate triage and isolation decisions. […] We also focus on the background and evolution of POCUS with studies showing the promising role of this diagnostic modality in COVID-19 infection. | 2020-11-04 |
| 33145478 | Pulmonary embolism is a common complication of severe coronavirus disease and a high degree of clinical suspicion for its diagnosis should be maintained in critically ill patients. | 2020-11-04 |
| 33145663 | The diagnostic utility of impact of lung ultrasound in critical-ill patients with COVID-19 for PE diagnostics however is unclear. | 2020-11-04 |
| 33146001 | Multivariable regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for age, sex, smoking status, rheumatic disease diagnosis, comorbidities, medication use prior to infection, and rheumatic disease activity. | 2020-11-04 |
| 33146037 | We included patients that described headache if the headache was not better explained by another ICHD-3 diagnosis. | 2020-11-04 |
| 33146156 | The rapid diagnosis of coronavirus disease 2019 (COVID-19) is a significant step towards the containment of the virus. […] Rapid point-of-care (PoC) assays (Truenat Beta CoV and Truenat SARS-CoV-2 assays) for the diagnosis of COVID-19 have been developed which are expected to shorten the turnaround time of reporting of results and also can be used for field investigations of COVID-19. […] The rapid PoC screening and confirmatory assays were prospectively validated at the State Level Virus Research and Diagnostic Laboratory at Bangalore Medical College and Research Institute, Bengaluru, under technical supervision by the Indian Council of Medical Research-National Institute of Virology (ICMR-NIV), Pune. | 2020-11-04 |
| 33146157 | A highly sensitive and specific antigen-based rapid diagnostic test (RDT) is the need of the hour. | 2020-11-04 |
| 33146237 | This letter aims to briefly clarify some analytical chemistry concepts, as sensitivity, cut-off and limit of detection, and their application towards clinical diagnosis. | 2020-11-04 |
| 33146318 | The aim of this study was to assess the differences, if any, between general dental practitioners (GDPs) and endodontists, in the diagnosis and treatment of endodontic emergencies during the worldwide outbreak of COVID-19. […] The responses showed agreement between endodontists and GDPs regarding the diagnosis of symptomatic irreversible pulpitis (SIP), symptomatic apical periodontitis (SAP), reversible pulpitis, and asymptomatic irreversible pulpitis (AIP). […] In conclusion, the most relevant findings in our survey were the differences between endodontists and GDPs in diagnosis, precheck triage, deep caries excavation procedures, and endodontic emergency pain relief strategies. | 2020-11-04 |
| 33146360 | The COVID-19 pandemic can significantly impact the management of HCC patients from diagnosis to treatment strategies. | 2020-11-04 |
| 33146371 | This review provides a comparative analysis of methodologies and findings to describe how structural biology techniques like X-ray crystallography and cryo-electron microscopy have enabled remarkable discoveries into the structure-function relationship of ACE and ACE2. | 2020-11-04 |
| 33146429 | Over the 20 weeks following March 11, 2020, the volume of screening mammograms and diagnostic mammograms fell by 58% and 38% of expected levels, on average. […] Lowest volumes were observed in week 15 (April 8 to 14), when screening and diagnostic mammograms fell by 99% and 74%, respectively. […] Volumes began to rebound in week 19 (May), with diagnostic mammograms reaching levels to similar to previous years’ and screening mammograms remaining 14% below expectations. | 2020-11-04 |
| 33146552 | During periods of high community prevalence of COVID-19, spirometry should only be used when it is essential for COPD diagnosis and/or to assess lung function status for interventional procedures or surgery. | 2020-11-04 |
| 33146561 | : Despite similarities, COVID-19-CSS appears to be distinct from HLH, MAS, and CRS, and the application of HLH diagnostic scores and criteria to COVID-19 is not supported by emerging data. | 2020-11-04 |
| 33146785 | Changes such as improved access to telemedicine, timing for cancer surgeries, and safer anesthetic techniques in response to the pandemic will change breast cancer surgical care beyond the pandemic era. | 2020-11-04 |
| 33147206 | Reverse transcription real-time polymerase chain reaction from a nasopharyngeal swab, authorized and validated by the World Health Organization, confirmed the diagnosis of SARS-CoV-2 infection. | 2020-11-04 |
| 33147214 | Since the RT-LAMP assay can be performed with a portable battery-supported device, it is a rapid, simple, and sensitive diagnostic assay for COVID-19 that can be available at point-of-care. | 2020-11-04 |
| 33147584 | Such evidence suggests that electronic auscultation is useful to aid diagnosis and timely management of the disease. | 2020-11-04 |
| 33147894 | The objective of this quasi-experimental study was to determine whether bolus vitamin D supplementation taken either regularly over the preceding year or after the diagnosis of COVID-19 was effective in improving survival among hospitalized frail elderly COVID-19 patients. […] Intervention groups were participants regularly supplemented with vitamin D over the preceding year (Group 1), and those supplemented with vitamin D after COVID-19 diagnosis (Group 2). | 2020-11-05 |
| 33148132 | The progressive nature of the disease will increase the mortality as time elapses between diagnosis and surgical intervention. | 2020-11-05 |
| 33148289 | Utilising data from the Netherlands Cancer Registry on provisional cancer diagnoses between 6 January 2020 and 4 October 2020, we assessed the impact of the temporary halt of national population screening programmes on the diagnosis of breast and colorectal cancer in the Netherlands. […] Forthcoming research is warranted to assess whether the decreased diagnostic scrutiny of cancer during the COVID-19 pandemic resulted in stage migration and altered clinical management, as well as poorer outcomes. | 2020-11-05 |
| 33148304 | There were no significant differences between patients in group 1 and control group 1 regarding time between appearance of B2 and CPP diagnosis, although group 1 patients had a significantly earlier chronological age at B2, a more advanced Tanner stage at diagnosis (p < 0.005), higher basal LH and E2 levels, higher LH peak after LHRH test (p < 0.05) and increased uterine length (p < 0.005) and ovarian volume (p < 0.0005). […] Our data show an increased incidence of newly diagnosed CPP and a faster rate of pubertal progression in patients with a previous diagnosis, during and after lockdown compared to previous years. | 2020-11-05 |
| 33148808 | Rapid, accurate, and easily configurable molecular diagnostic tests are imperative to prevent global spread of new diseases. […] CRISPR-based diagnostic approaches are proving to be useful as field-deployable solutions. […] Unlike previous CRISPR diagnostic assays, we also use ITP for automated purification of target RNA from raw nasopharyngeal swab samples. […] This electric field control enables an alternate modality for a suite of microfluidic CRISPR-based diagnostic assays. | 2020-11-05 |
| 33149153 | One of the most important methods for COVID-19 detection is the use of techniques such as real time RT-PCR based on a previous extraction/purification of RNA procedure from nasopharyngeal cells using functionalized magnetic nanoparticles (MNP). | 2020-11-05 |
| 33149652 | In discriminating the critical and mild patients, a panel combining PCT, IL-6, and neutrophil (NEUT) yielded the best diagnostic performance with an AUC of 0.99, the sensitivity of 90.60% and specificity of 100%. | 2020-11-05 |
| 33150094 | Using normalization and mapping techniques, we identified Hydroxychloroquine (92 studies) as the most common drug intervention, while convalescent plasma (20 studies) is the most common biological intervention. | 2020-11-05 |
| 33150470 | We retrospectively analysed 502 patients with COVID-19 (mean age 61 ± 16 years, range 15-99) treated at our hospital with a proven diagnosis of SARS-CoV-2 infection hospitalised between 21 February and 30 April 2020 and treated with at least two drugs. | 2020-11-05 |
| 33150973 | To reduce patient mortality, kidney complications should be given increased attention in the diagnosis and treatment of coronavirus disease 2019 (COVID-19). | 2020-11-05 |
| 33151049 | A diagnosis of chronic kidney disease increases the risk of infection. | 2020-11-05 |
| 33151180 | Currently, routine polymerase chain reaction testing remains limited by supply shortages possibly delaying diagnosis until later in the course of the disorder and thus altering the symptom complex at presentation. | 2020-11-05 |
| 33151419 | It is hoped that this review will provide interesting information for the future development of new reliable nano-based platforms for point-of-care diagnostic devices for COVID-19 prevention and control. | 2020-11-05 |
| 33151629 | A rapid and accurate detection method for the antibody is significant to the disease diagnosis, especially for the epidemic. | 2020-11-05 |
| 33151912 | We report on a case of SARS-CoV-2/MBT coinfection in a 51-year-old taxi driver from Mexico City that underscores the importance of rapid and accurate laboratory testing, diagnosis, and treatment. […] CASE REPORT We present the case of a man in the sixth decade of life who was admitted to the National Institute of Respiratory Diseases (INER) with a diagnosis of COVID-19 pneumonia, which was confirmed by nasopharyngeal exudate using real-time polymerase chain reaction (RT-PCR) for the identification of SARS-CoV-2. […] CONCLUSIONS The present report underscores the importance of using validated molecular diagnostic tests to identify coinfections in areas where there is a high prevalence of other causes of pneumonia, such as MBT, as a way to improve clinical outcomes in patients during the COVID-19 pandemic. […] We must remain alert to any clinical subtleties so as to ensure timely and accurate diagnosis and stay one step ahead of COVID-19. | 2020-11-05 |
| 33151983 | The measurements included demographic, socio-economics, symptoms, health service diagnosis and treatment, contact history, and psychological variables. | 2020-11-05 |
| 33152043 | We focus on the single-day diagnosis, demographics (gender and age), regional distribution, incubation period and symptoms. […] The interval from the onset of initial symptoms to laboratory diagnosis was 4.0 days in local cases, while that of imported cases was 4.5 days. | 2020-11-05 |
| 33152084 | Quality control, pooled COVID-19, and non-COVID-19 patient specimens were used for the imprecision study. 246 specimens from 70 patients with COVID-19 diagnosis were tested to study the sensitivity. 73 non-COVID-19 control specimens were measured to study the specificity. | 2020-11-05 |
| 33152093 | Physical therapist interventions included body positioning, airway clearance techniques, oscillatory positive end-expiratory pressure, inspiratory muscle training, and mobility exercises. | 2020-11-05 |
| 33152146 | This study aimed to assess the diagnostic test accuracy (DTA) of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) serological test methods and the kinetics of antibody positivity. […] We included articles evaluating the diagnostic accuracy of serological tests and the kinetics of antibody positivity. | 2020-11-05 |
| 33152185 | Patients with cancer have a higher risk to acquire the infection and worse prognosis as they have to attend more medical visits in healthcare institutions, receive medical and surgical treatments, and be subjected to diagnostic studies such as PET/CT in nuclear medicine services where the infection may be an incidental finding.We present here F18-FDG PET/CT (Positron Emission Tomography and Computed Tomography with 2-deoxy-2-[fluorine-18]fluoro-D-glucose), images with findings of COVID-19 from patients with different oncological conditions but no respiratory symptoms. | 2020-11-05 |
| 33152186 | We describe the identification of the virus and the clinical course, diagnosis, and treatment of the infection including her rapid clinical deterioration from the mild initial symptoms, which progressed to multilobar pneumonia requiring admission to the intensive care unit.This case highlights the importance of establishing a diagnosis based on the clinical findings and the patient’s history bearing in mind the possibility of gastrointestinal symptoms in addition to respiratory ones. […] Furthermore, limitations in diagnostic tests and the possibility of co-infection with other respiratory pathogens are highlighted. | 2020-11-05 |
| 33152193 | Future studies comparing the performance of the departments and districts will improve the diagnosis of the Colombian surveillance system. | 2020-11-05 |
| 33152195 | Introduction: Infection with the new SARS-Cov-2 coronavirus is a worldwide public health emergency; its diagnosis is based on molecular tests, while its prognosis depends on the patient’s history and on some paraclinical tests. | 2020-11-05 |
| 33152197 | Introduction: Rapid IgM-IgG combined antibody tests can play an important role in the COVID-19 surveillance by supporting the diagnosis of infection, assessing the immune response, and verifying the progress towards herd immunity.Objective: To evaluate the performance of rapid IgM-IgG combined antibody tests in COVID-19 occupational surveillance in a group of Colombian enterprises. […] Conclusion: Antibody rapid tests have a role in the diagnostic process of infection and they must be evaluated taking into account the moment of the epidemic, the type of test purchased, and the populations at risk since their results depend on the number of infections and cases. | 2020-11-05 |
| 33152512 | These findings should facilitate rapid COVID-19 diagnosis and triage in settings without testing. | 2020-11-05 |
| 33152573 | Patients with a confirmed diagnosis of COVID-19 based on laboratory (PCR) were stratified into two groups based on presence of olfactory dysfunction (OD). | 2020-11-05 |
| 33152666 | With the persistent COVID-19 pandemic, there is an urgent need to use rapid and reliable diagnostic tools for highly urgent cases. […] Among molecular tools allowing a diagnosis in less than an hour, only one, the Cepheid Xpert Xpress SARS-CoV-2 assay, has exhibited a good sensitivity. […] We evaluated the VitaPCR™ RT-PCR assay, whose sample analysis time is of approximately 20 min, in nasopharyngeal secretions from 534 patients presenting to our Institute, for the diagnosis of COVID-19, and compared it to our routine RT-PCR assay. […] Compared to our routine RT-PCR and the previous diagnosis of COVID-19, the sensitivity, specificity, positive and negative predictive values of VitaPCR™ can be evaluated to be 99.3 % (155/156), 94.7 % (358/378), 88.6 % (155/175) and 99.7 % (358/359), respectively. […] The VitaPCR™ SARS-CoV-2 is an accurate rapid test, suitable for clinical practice that can be performed as part of a point-of-care testing, for the rapid diagnosis of COVID-19. | 2020-11-05 |
| 33152914 | So, as COVID-19 has called ideas for treatment, controlling, and diagnosis, we discussed the application of Clustered Regularly Interspaced Short Palindromic Repeats/Cas13 (CRISPR/Cas13) as a treatment of COVID-19, which received less attention compared with other potential therapeutic options. | 2020-11-06 |
| 33152991 | Although the reference standard for SARS-CoV-2 diagnosis is real-time reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) is recommended for both initial evaluation and follow-up. | 2020-11-06 |
| 33153105 | Computed tomography (CT) images are currently being adopted as the visual evidence for COVID-19 diagnosis in clinical practice. | 2020-11-06 |
| 33153634 | A simple point-of-care diagnostic test to screen for ventricular dysfunction would be clinically useful to guide management. […] One other patient had a pre-existing EF less than or equal to 40%, accurately detected by the algorithm before and after COVID-19 diagnosis, and another was found to have a low EF by AI ECG and echocardiography with the COVID-19 diagnosis. | 2020-11-06 |
| 33153907 | In the face of this medical challenge threatening humans, the development of rapid and accurate methods for early screening and diagnosis of COVID-19 became crucial to containing the emerging public health threat, and prevent further spread within the population. […] Therefore, the use of both qRT-PCR and serological testing in the diagnosis of COVID-19 in China and elsewhere, presented considerable challenges, but when used in combination, can be valuable tools in the fight against COVID-19. […] In this review, we give an overview of the advantages and disadvantages of different molecular techniques for SARS-CoV-2 detection that are currently used in several labs, including qRT-PCR, gene sequencing, loop-mediated isothermal amplification (LAMP), nucleic acid mass spectrometry (MS), and gene editing technique based on clustered regularly interspaced short palindromic repeats (CRISPR/Cas13) system. […] Then we mainly review and analyze some causes of false-negative qRT-PCR results, and how to resolve some of the diagnostic dilemma. | 2020-11-06 |
| 33154231 | A well-established and functional quality management system is an integral part of any diagnostic laboratory. […] A pandemic situation such as that caused by the influenza H1N1 2009 virus or the recent severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) increases the demands on the public health system, and the need to build, upgrade and expand the number of diagnostic laboratories. […] The implementation of quality system in diagnostic laboratories would ensure accurate, reliable and efficient test results at par with the international standards. […] Biosafety considerations should include the guidelines laid out by the WHO, the Institutional Biosafety Committee and the Department of Biotechnology, Government of India for carrying out diagnostic work in the laboratory. […] Currently, there are 1922 laboratories, operational for COVID-19 diagnosis in India. | 2020-11-06 |
| 33154236 | Since the whole genome sequences of a number of strains of this novel RNA virus were available in the public domain by early January 2020, a number of real-time polymerase chain reaction (RT-PCR) protocols were designed and used for diagnosis of this infection. | 2020-11-06 |
| 33154251 | In the absence of effective treatment or vaccine, the current strategy for the prevention of further transmission of severe acute respiratory syndrome (SARS) CoV-2 (COVID-19) infection is early diagnosis and isolation of cases. […] The diagnosis of SARS-CoV-2 is done by detecting viral RNA in the nasopharyngeal and throat swabs by real-time polymerase chain reaction (PCR). | 2020-11-06 |
| 33154262 | In the current COVID-19 crisis, many national healthcare systems are confronted with a huge demand for mass testing and an acute shortage of diagnostic resources. | 2020-11-06 |
| 33154279 | From these findings, the predictive ability of symptoms for COVID-19 diagnosis was extremely weak. | 2020-11-06 |
| 33154801 | Therefore, the aim of this review was to present a new proposal for a care protocol in Peruvian Dentistry: Provisional review of the diagnosis, treatment, epidemiological characteristics, routes of transmission and recommendations of COVID-19. | 2020-11-06 |
| 33155253 | This study aims to discuss the unique clinical features of patients with 2019-nCoV in Zhengzhou City to provide references for clinical diagnosis and treatment. | 2020-11-06 |
| 33155254 | Instant diagnostic and adequate therapeutics serve as a major intervention for the management of pandemic containment. | 2020-11-06 |
| 33155934 | Results In none of the cases, myocarditis was suspected clinically, added to the diagnosis or indicated as a possible cause of death. […] The morphological examination of the heart identified signs of lymphocytic myocarditis consistent with Dallas criteria for this diagnosis. | 2020-11-06 |
| 33155954 | The diagnosis was based on the clinical picture of community-acquired pneumonia, data of chest multispiral computed tomography, and a positive test for COVID-19. | 2020-11-06 |
| 33155999 | Longer duration from transplant to disease diagnosis, hypoxia and higher LDH were associated with mortality (P<0.05). | 2020-11-06 |
| 33156022 | The consistent perieccrine and vasculopathic features represent important pathologic findings in the diagnosis of COVID toes and are suggestive of pathogenetic mechanisms. | 2020-11-06 |
| 33156238 | Mitigation strategies including barrier drapes and alternative techniques such as endoscopic surgery or use of exoscopes should also be considered. | 2020-11-06 |
| 33156298 | Saliva secretion itself is also a diagnostic parameter. | 2020-11-06 |
| 33156463 | Histoplasmosis must be included as a diagnostic possibility in opportunistic fungal co-infections in COVID-19 patients with AIDS, mainly in endemic areas. | 2020-11-06 |
| 33156694 | A retrospective analysis was conducted on patients undergoing emergency surgery for the clinically suspected diagnosis of acute appendicitis during the 2-month period of March and April 2020 and the same time interval in the previous year. | 2020-11-06 |
| 33156775 | Accurate and rapid diagnosis of COVID-19 suspected cases plays a crucial role in timely quarantine and medical treatment. […] Developing a deep learning-based model for automatic COVID-19 diagnosis on chest CT is helpful to counter the outbreak of SARS-CoV-2. | 2020-11-06 |
| 33156812 | This paper presents the protocol of a study that aims to prospectively evaluate patients with IMRD and a confirmed COVID-19 diagnosis (using criteria provided by the Brazilian Ministry of Health). | 2020-11-06 |
| 33157033 | Chest CT categorical classification of COVID-19 findings is reproducible and demonstrates high level of agreement with clinical and RT-PCR diagnosis of COVID-19. | 2020-11-06 |
| 33157110 | Structural equation modelling (SEM) techniques were used to test the theoretically-indicated relations among the variables. | 2020-11-06 |
| 33157295 | The results confirm the possibility of finding this virus in floating particulate matter in contaminated zones, with a simple and economic sampling method based on filtration technology through 0.22 μm pores and detection with molecular techniques (RT-PCR). | 2020-11-06 |
| 33157338 | The diagnosis was difficult given this atypical presentation, confounded by global scenario. | 2020-11-06 |
| 33158469 | Survival following liver transplantation has changed dramatically owing to improvement in surgical techniques, peri-operative care and optimal immunosuppressive therapy. | 2020-11-07 |
| 33158555 | This report demonstrates the need for emergency psychiatric services throughout the COVID-19 pandemic and the need for clinical and diagnostic COVID-19 screening of psychiatric emergency patients. | 2020-11-07 |
| 33158840 | To identify the diagnostic accuracy of common imaging modalities, chest X-ray (CXR) and CT, for diagnosis of COVID-19 in the general emergency population in the UK and to find the association between imaging features and outcomes in these patients. […] Sensitivity and specificity of CXR and CT for diagnosis of COVID-19 using the British Society of Thoracic Imaging reporting templates. […] Sensitivity and specificity of CXR for COVID-19 diagnosis were 0.56 (95% CI 0.51 to 0.60) and 0.60 (95% CI 0.54 to 0.65), respectively. […] CT has substantially improved diagnostic performance over CXR in COVID-19. | 2020-11-07 |
| 33158968 | COVID-19 diagnosis is defined as (1) certain if confirmed by reverse transcriptase PCR assay of nasopharyngeal swabs (NPS); (2) suspected in case of new symptoms or CT scan evidence of interstitial pneumonia with negative/not performed NPS; (3) negative in case of neither symptoms nor radiological evidence. […] During the pandemic peak, accurate protective measures successfully resulted in low rates of COVID-19 diagnosis, although with high lethality. | 2020-11-07 |
| 33159508 | The practice model approach to include a virtual diagnostic clinic with increased patient and provider efficiency was created to enhance accessibility for patients and sustainability for providers. | 2020-11-07 |
| 33159952 | Assays for IgA and IgM have limited diagnostic performance and do not prove an additional value for population-based screening approaches. | 2020-11-07 |
| 33159953 | Highly sensitive laboratory techniques played a critical role in clinical COVID-19 diagnosis and management. […] In this study the feasibility of using a new digital PCR-based detection assay for clinical COVID-19 diagnosis was investigated by comparing its performance with that of RT-PCR. | 2020-11-07 |
| 33160015 | Although other diagnostic methods have been introduced, detection of viral genes on oro- and nasopharyngeal swabs by reverse-transcription real time-PCR (rRT-PCR) assays is still the gold standard. | 2020-11-07 |
| 33160088 | Local public health measures were effective in reducing the time between symptom onset and laboratory diagnosis and the number of close contacts per case. | 2020-11-07 |
| 33160178 | Disease diagnosis, appropriate clinical management and infection control are all important factors in controlling the spread of SARS-CoV-2. | 2020-11-07 |
| 33160179 | RT-qPCR is the current recommended laboratory method to diagnose SARS-CoV-2 acute infection, several factors such as requirement of special equipment, time consuming, high cost and skilled staff limit the use of these techniques. | 2020-11-07 |
| 33160700 | In this post-hoc analysis of a prospective observational cohort study, we enrolled all adult (age ≥18 years) patients with a confirmed diagnosis of COVID-19 who had been discharged home from either a medical ward or the Emergency Department of San Raffaele University Hospital, and were re-evaluated after remission at the Outpatient COVID-19 Follow-Up Clinic of the same Institution from April 7, 2020, to May 11, 2020. | 2020-11-08 |
| 33161030 | We aimed to describe histological features of cutaneous eruptions occurring concomitantly to SARS-CoV-2 infection and assess by immunochemistry and in situ hybridization using RNAscope validation techniques the presence of the virus in skin lesions. […] Even if, at least for a few cases, the differential diagnosis with drug hypersensitivity reaction can be difficult, these cutaneous eruptions seem to rather correspond to paraviral rashes. | 2020-11-08 |
| 33161241 | A questionnaire has been developed to collect pseudonymised patient data on patients’ characteristics, cancer diagnosis and treatment. […] All patients with COVID-19 and a cancer diagnosis or treatment in the past 5 years are eligible. […] In multivariable analyses, age ≥65 years (p < 0.001), male gender (p = 0.035), prior or other malignancy (p = 0.045) and active diagnosis of haematological malignancy (p = 0.046) or lung cancer (p = 0.003) were independent risk factors for a fatal outcome of COVID-19. | 2020-11-08 |
| 33161256 | We suggest that checking oxidized albumin in COVID-19 patients may provide new therapeutic and diagnostic opportunities to better combat COVID-19. | 2020-11-08 |
| 33161334 | The deep learning community concentrates their efforts on exploring if neural networks can potentially support the diagnosis using CT and radiograph images of patients’ lungs. | 2020-11-08 |
| 33161369 | The diagnostic specificity was 100 % for IgM and 99.67 % for IgG using 300 pre-COVID-19 serum specimens. […] The diagnostic sensitivity for the SARS-CoV-2 IgG assay post symptom onset was 23.2 % at ≤7 days, 69.5 % at 8-14 days, 93.6 % at 15-21 days, and 99.6 % at 4-5 weeks (peak test sensitivity). […] In symptomatic patients who test negative by PCR for a SARS-CoV-2 infection, assessing IgM and IgG antibodies can aid in supporting a diagnosis of COVID-19. | 2020-11-08 |
| 33161423 | However, achieving high f lu vaccination coverage would mean avoiding hospital overload due to hospitalizations for f lu complications and facilitating a timely differential diagnosis that allows a quick and appropriate treatment of CoViD-19 cases. | 2020-11-08 |
| 33161427 | Compared to the gold-standard combined ELISA+immunofluorescence, the MEDsan IgG rapid diagnostic test performed accurately. | 2020-11-08 |
| 33161494 | Finally, these findings reinforce the differential diagnosis with other potential causes of sense of smell loss, during the COVID-19 outbreak. | 2020-11-08 |
| 33161508 | COVID-19 thrombosis includes macro- and microthrombosis, with diagnosis of the latter depending on markers of coagulation and fibrinolysis. | 2020-11-08 |
| 33161729 | Harnessing technology for accurate diagnosis and staging will improve patient outcomes and minimize serious consequences of false-positive test results. | 2020-11-09 |
| 33162312 | A COVID-19 diagnosis was independently associated with an increase in nursing time (OR = 4.8, 95% CI:3.6-6.4). | 2020-11-09 |
| 33162382 | The common diagnosis method for detection COVID-19 was according to clinical manifestation, epidemiological histories, and ancillary tests, like CT scan, nucleic acid detection, immune identification technology, blood culture, Radiology, and enzyme-linked immunosorbent assay (ELISA). | 2020-11-09 |
| 33162440 | Six patients were negative for IgG antibody at an average of 26 days (range: 11-39 days) after the COVID-19 diagnosis. […] These patients were also positive for IgG antibody after the confirmed diagnosis based on PCR accompanied with the development of pneumonia. | 2020-11-09 |
| 33162646 | The early diagnosis of COVID-19 is complicated by its strong transmission characteristics and no obvious symptoms in the incubation period. […] Taking a typical fever clinic as an object of study, two links in the actual diagnosis and treatment process are selected in this manuscript for investigation by experimental and numerical methods. | 2020-11-09 |
| 33162722 | Various protein separation and identification techniques are available which facilitates the analysis of various types of interactions among proteins and their evolutionary lineages. | 2020-11-09 |
| 33162746 | 38.9%, P=0.001), and for the performance of basic diagnostic (70.1% vs. | 2020-11-09 |
| 33162783 | Of all the analytical techniques, electrochemical methods have the established capabilities to address the issues. | 2020-11-09 |
| 33162872 | Artificial intelligence models are found to be very successful in the diagnosis of various diseases in the biomedical field In this paper, an integrated stacked deep convolution network InstaCovNet-19 is proposed. | 2020-11-09 |
| 33163005 | By shifting ncRNA differences into comparative diagnostic and therapeutic profiles, our RNA-sequencing based Resource can identify ncRNA regulating candidates for COVID-19 and its associated immediate and predicted long-term inflammation and neurological complications, and sex-related therapeutics thereof. | 2020-11-09 |
| 33163103 | Chest CT scan is commonly used as a diagnostic and triage tool in patients admitted to hospitalization. | 2020-11-09 |
| 33163104 | In response to the emergence of Sars-CoV-2 responsible for a global pandemic, a large number of diagnostic tests have been developed and brought to market in a very short period of time. […] RT-PCR on nasopharyngeal swab samples is the reference method for the diagnosis and screening of Sars-CoV-2 infection, but the tests developed are highly variable in terms of sensitivity and turnaround time. […] Despite the need to respond rapidly to an urgent diagnostic need, it remains essential to validate the methods chosen on a well-characterized panel of samples, as the performance of certain tests is sometimes unsatisfactory to ensure a reliable diagnosis. | 2020-11-09 |
| 33163105 | These data made it possible to better understand the origin of this virus, to date its emergence in China, but also in France, and to analyse the spread of the epidemic using techniques from the emerging field of phylodynamics. | 2020-11-09 |
| 33163413 | However, only 21% of the patients were more afraid of COVID-19 than of their cancer, in particular patients with long-term (> 12 months) vs. short-term cancer diagnosis (28% vs. | 2020-11-09 |
| 33163466 | RT-PCR is more reliable than CT in the initial diagnosis of pediatric patients with COVID-19. | 2020-11-09 |
| 33163530 | However, these techniques are expensive and not readily available for point-of-care (POC) applications. […] All sensing and biosensing techniques developed for the determination of various classes of coronaviruses are useful to recognize the newly immerged coronavirus, i.e., SARS-CoV-2. | 2020-11-09 |
| 33163949 | In 2020, 7.1% (21/293) of patients had a diagnosis of an active COVID-19 infection: 11 (52.4%) patients were hospitalised and 4 (19.1%) patients died. […] During the coronavirus disease 2019 (COVID-19) pandemic era, fewer patients with hepatocellular carcinoma (HCC) presented to the multidisciplinary tumour board, especially with a first diagnosis of HCC. | 2020-11-09 |
| 33163955 | Results returned after his death showed homozygous C282Y mutation of the HFE gene consistent with a diagnosis of HH. | 2020-11-09 |
| 33164544 | A total of 81 patients who had hydroxychloroquine and azithromycin combination therapy because of possible or reverse-transcription polymertase chain reaction (RT-PCR) confirmed diagnosis of COVID-19 were included in the study. | 2020-11-09 |
| 33164589 | The prime concern is to device novel tools for rapid and precise diagnosis, drug delivery, and effective therapies for coronavirus. […] The tools for diagnosis of coronavirus, nano-based vaccines, and nanoparticles as a drug delivery system for the treatment of virus infection have been discussed. […] The research on nanotechnology-based diagnosis, drug delivery, and antiviral therapies is at a preliminary stage. […] Nanoparticles are a promising tool for prevention, diagnosis, antiviral drug delivery, and therapeutics, which may open up new avenues in the treatment of COVID-19. | 2020-11-09 |
| 33164982 | Accurate and rapid diagnosis of coronavirus disease (COVID-19) is crucial for timely quarantine and treatment. | 2020-11-09 |
| 33165007 | Taken together, these studies indicate that HIV infection may be associated with increased risk of COVID-19 diagnosis, but comorbidities appear to play a larger role than HIV-specific variables in outcomes of COVID-19 among PWH. | 2020-11-09 |
| 33165308 | In particular, we have found data supporting the importance of data sharing, model sharing, preprint archiving, social media, medical case sharing, distance learning and continuous medical education, smartphone apps, telemedicine, robotics, big data analysis, machine learning, and deep learning, with the ultimate goal of optimization of individual prevention, diagnosis, tracing, risk-stratification, treatment and rehabilitation. | 2020-11-09 |
| 33165486 | We aimed to develop a visual diagnostic platform for SARS-CoV-2 based on colorimetric RT-LAMP with levels of sensitivity and specificity comparable to that of commercial qRT-PCR assays. […] The diagnostic performance of the developed RT-LAMP assay was evaluated in 2120 clinical specimens and compared with the commercial qRT-PCR. […] In summary, our results indicate that the developed colorimetric RT-LAMP provides a simple, sensitive and reliable approach for the detection of SARS-CoV-2 in clinical samples, implying its beneficial use as a diagnostic platform for COVID-19 screening. | 2020-11-09 |
| 33165573 | Early COVID-19 diagnosis prior to laboratory testing results is crucial for infection control in hospitals. […] Models exist predicting COVID-19 diagnosis, but significant concerns exist regarding methodology and generalisability. […] To generate the first COVID-19 diagnosis risk score for use at the time of hospital admission using the TRIPOD (transparent reporting of a multivariable prediction model for individual prognosis or diagnosis) checklist. […] A multivariable diagnostic prediction model for COVID-19 using the TRIPOD checklist applied to a large single-centre retrospective observational study of patients with suspected COVID-19. 581 individuals were admitted with suspected COVID-19; the majority had laboratory-confirmed COVID-19 (420/581, 72.2%). […] Our risk score is intended for diagnosis of COVID-19 in individuals admitted to hospital with suspected COVID-19. […] The score is the first developed for COVID-19 diagnosis using the TRIPOD checklist. | 2020-11-09 |
| 33165767 | In overwhelmed emergency departments (EDs) facing COVID-19 outbreak, a swift diagnosis is imperative. […] Here we report the diagnostic role of CT in two EDs in Lombardy, epicenter of Italian outbreak. […] CT scans were classified in “highly likely,” “likely,” and “unlikely” COVID-19 pneumonia according to the presence of typical, indeterminate, and atypical findings, or “negative” in the absence of findings, or “alternative diagnosis” when a different diagnosis was found. […] CT diagnostic performances were assessed considering RT-PCR as reference standard. […] In 21 (15%) patients a differential diagnosis was provided, including typical pneumonia, pulmonary edema, neoplasia, and pulmonary embolism. […] CT diagnostic accuracy in respect of the first test swab was 79% and increased to 91.5% after repeated swabs and/or BAL, for 18 false-negative first swab. […] Chest CT was useful to streamline patients’ triage while waiting for RT-PCR in the ED, supporting the clinical suspicion of COVID-19 or providing alternative diagnosis. | 2020-11-09 |
| 33166189 | Children 0 to 18 years of age admitted to a hospital between February 1 and June 6, 2020, with a diagnosis of an inflammatory syndrome and acute cardiovascular complications were included. | 2020-11-09 |
| 33166283 | We report the first case of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, unveiling the diagnosis of asymptomatic filariasis. […] In order not to miss relevant concomitant diagnoses, it is prudent to keep a broad differential diagnosis when faced with SARS-CoV-2-infected patients; this is especially true when atypical symptoms are present or in areas endemic with other infections. | 2020-11-09 |
| 33166287 | Female gender and those with a pre-existing diagnosis of depression/anxiety were over-represented in those with fatigue. | 2020-11-09 |
| 33166549 | Biolidics LFI showed clinical sensitivity of 92% with venous blood at 7 days after PCR diagnosis of SARS-CoV-2. | 2020-11-09 |
| 33166657 | Diagnosis of viral myocarditis should be based on the molecular assessment of endomyocardial biopsy or autopsy by polymerase chain reaction or in-situ hybridization. | 2020-11-09 |
| 33166683 | Regarding the high price and low availability of sequencing techniques in developing countries, here we describe a rapid and inexpensive method for the detection of D614G mutation in SARS-CoV-2. | 2020-11-09 |
| 33167051 | However, 22 % of the centres stated that liver decompensation was diagnosed late and 9.4 % stated that diagnosis of hepatocellular carcinoma was delayed. […] Diagnosis, therapy and monitoring of patients with chronic hepatitis C were impaired during the COVID-19 pandemic. […] However, the fact that the diagnosis of liver decompensations with potential lethal consequences was delayed in a considerable number of patients causes major concern. | 2020-11-09 |
| 33167242 | As COVID-19 has reached pandemic status and the number of cases continues to grow, widespread availability of diagnostic testing is critical in helping identify and control the emergence of this rapidly spreading and serious illness. […] However, a lacking in making a quick reaction to the threat and starting early development of diagnostic sensing tools has had an important impact globally. […] In this regard, here we will review critically the current developed diagnostic tools in response to the COVID-19 pandemic and compare the different types through the discussion of their pros and cons such as nucleic acid detection tests (including PCR and CRISPR), antibody and protein-based diagnosis tests. […] In addition, potential technologies that are under development such as on-site diagnosis platforms, lateral flow, and portable PCR units are discussed. | 2020-11-10 |
| 33167445 | One of the most effective ways to prevent the spread of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is to develop accurate and rapid diagnostic tests. […] This work includes studies from recent literature publications along with information from the manufacturer’s manuals of commercially available SARS-CoV-2 diagnostic products. […] The viral components targeted for virus detection, the principles of each diagnostic technique, and the detection efficiency of each approach are discussed. […] The potential of using diagnostic tests that were originally developed for previous epidemic viruses is also presented. | 2020-11-10 |
| 33167846 | In this review, we have discussed the updates on transmission, diagnosis, genome analysis and comparison, treatment options and clinical trials of COVID-19. | 2020-11-10 |
| 33167921 | In addition, clinical trials should be undertaken to assess neural mobilization techniques and proprioceptive neuromuscular facilitation should be included in the therapy. | 2020-11-10 |
| 33167955 | Renal recovery during hospitalization was identified among 16 patients with AKI (17.4%), who had a significantly shorter time from admission to AKI diagnosis, lower incidence of right heart failure and higher ratio of partial pressure of oxygen to the fraction of inspired oxygen. | 2020-11-10 |
| 33168109 | As the pathophysiology of COVID-19 emerges, this paper describes dysphagia as a sequela of the disease, including its diagnosis and management, hypothesised causes, symptomatology in relation to viral progression, and concurrent variables such as intubation, tracheostomy and delirium, at a tertiary UK hospital. | 2020-11-10 |
| 33168360 | The aim of the current longitudinal, individualized, single-blind, prospective, self-controlled, and accurate study is to evaluate the quality of images generated through, and confidence level of, diagnosis based on videolaryngoscopy performed with intraoral dental camera equipped with disposable protection cap and connected to 70° rigid laryngoscope in vocally healthy individuals. […] There was no statistically significant difference in image quality between examinations performed with, and without, protection cap (P= 0.646) or in the diagnosis confidence level of examinations performed with, or without, the barrier method. | 2020-11-10 |
| 33168452 | Therefore, the aim of this article is to describe the different most used diagnostic tests and analyze their validity and indications for use according to scientific evidence and the main recommendations of scientific societies and reference organizations at national and international level. | 2020-11-10 |
| 33168521 | Respiratory viruses (RVs) is a common cause of illness in people of all ages, at present, different types of sampling methods are available for respiratory viral diagnosis. […] This network meta-analysis provides supporting evidences that NPW, MTS and NPS have higher diagnostic value regarding RVs infection, moreover, particular preferred methods should be considered in terms of specific virus pandemic. | 2020-11-10 |
| 33168538 | Given the patient had no primary liver disease prior to admission, we considered secondary causes of cholestatic liver injury; this led us to an unusual diagnosis of secondary sclerosing cholangitis in critically ill patients. | 2020-11-10 |
| 33169059 | Establishing a stepwise approach for proper diagnosis and risk stratification, with an emphasis on contemporary cardiac magnetic resonance (CMR) imaging techniques, in myocarditis is critical. […] After a diagnosis of myocarditis is made, it is imperative for any athlete or highly active individual to refrain from physical exercise. | 2020-11-10 |
| 33169084 | According to the Chinese ‘Seventh Edition of the COVID-19 Diagnosis and Treatment Protocol’, suspected patients with negative nucleic acid tests from two consecutive airway specimens can be excluded from diagnosis and released from quarantine. […] The diagnosis was confirmed after the SARS-CoV-2 nucleic acid was detected after four sputum sample tests (sampling interval of at least 24 h). | 2020-11-10 |
| 33169086 | Patient visits to primary care physicians as well as to specialists and admissions to hospitals have been significantly reduced with the possible effect of reduced early diagnosis and treatment. | 2020-11-10 |
| 33169090 | We performed a retrospective review of electronic medical records of the patients admitted with an initial diagnosis of COVID-19. | 2020-11-10 |
| 33169099 | In the field of healthcare, deep learning has been implemented in many applications, e.g., diabetic retinopathy detection, lung nodule classification, fetal localization, and thyroid diagnosis. | 2020-11-10 |
| 33169104 | Computed tomography (CT) is used for initial diagnosis and therapy monitoring of patients with coronavirus disease 2019 (COVID-19). […] The aim of this study was to evaluate parameter settings for two commonly used CT scanners to ensure sufficient image quality/diagnostic confidence at a submillisievert dose. […] With the tested parameters, we achieved applied doses in the submillisievert range, on two different CT scanners without sacrificing diagnostic confidence regarding COVID-19 findings. | 2020-11-10 |
| 33169110 | Briefly, this article highlights the gut microbiome’s relation and provides potential diagnostic approaches like RDT and LC-MS for sensitive and specific identification of viral proteins. […] Altogether, this article reviews epidemiology, probable receptors and put forward the tentative ideas of the therapeutic targets and diagnostic methods for COVID-19 with gastrointestinal aspect of disease. | 2020-11-10 |
| 33169117 | In addition to the worldwide efforts to share clinical and routine population health data, there are many large-scale efforts to collect and disseminate medical imaging data, owing to the critical role that imaging has played in diagnosis and management around the world. […] Given these issues surrounding COVID-19, many groups began to explore the benefits of ‘big data’ processing and algorithms to assist with the diagnosis and therapeutic development of COVID-19. | 2020-11-10 |
| 33169119 | In conclusion, sputum is most sensitive for routine laboratory diagnosis of COVID-19, followed by nasal swabs. […] Detection of viral RNA in BALF improves diagnostic accuracy in severe COVID-19 patients. | 2020-11-10 |
| 33169254 | There has been much academic debate, media attention, and conversation in the homes of everyday individuals about the allocation of medical resources, diagnostic testing kits, ventilators, and personal protective equipment. | 2020-11-10 |
| 33169487 | Chest radiographics show characteristic patterns and distributions, which can be used as an adjunct in the diagnosis and follow-up of COVID-19 patients in specific clinical contexts. | 2020-11-10 |
| 33169643 | Conclusions Myocardial injury with hs-cTnT ≥20 ng/L, in addition to cardiac conduction perturbations, especially AF/AFL, upon hospital admission for COVID-19 infection is associated with markedly increased risk for mortality than either diagnostic abnormality alone. | 2020-11-10 |
| 33169720 | Early diagnosis of Covid-19 disease is essential in pregnant women. | 2020-11-10 |
| 33169723 | A rapid review METHODS: We reviewed the daily new cases of COVID-19 based on hospitalized and outpatients, reported deaths, and diagnostic testing in Iran. | 2020-11-10 |
| 33169915 | For bioaerosols, having more complex biological and biochemical identity, we will start from air sampling techniques, followed by a discussion of various detection methods (plate culture, molecular methods, immunoassays and biosensors) in association with compatible sampling technologies. | 2020-11-10 |
| 33169943 | Using a consensus process, seven nurse experts created the linkages for individuals during the COVID 19 pandemic using the following steps: (a) creating an initial list of potential nursing diagnoses, (b) selecting and categorizing outcomes that aligned with all components of each nursing diagnosis selected, and (c) identifying relevant nursing interventions. | 2020-11-10 |
| 33170104 | varied based on CT vendors (7-11mGy, p<0.001), number of detector-rows (8-9mGy, p<0.001), year of CT installation (7-10mGy, p=0.006), and reconstruction techniques (7-10mGy, p=0.03). | 2020-11-10 |
| 33170317 | Thorough comprehension of the role that ACE2 plays in different pathways will be the key to assess the impact that SARS-CoV-2/ACE2 binding has on organismal physiology and will help us to find better therapies and diagnostic tools. | 2020-11-10 |
| 33170391 | Furthermore, they might react differently, according to their main diagnosis. | 2020-11-10 |
| 33170799 | Digital symptom checkers are artificial intelligence-supported software tools that use a conversational “chatbot” format to support rapid diagnosis and consistent triage. | 2020-11-10 |
| 33170802 | Individuals with arthritis use Twitter to communicate with peers, and to receive up-to-date information from health professionals and services about novel therapies and management techniques. | 2020-11-10 |
| 33170924 | The detection of antibody response by serological testing provides a supplementary diagnostic tool to molecular tests. | 2020-11-10 |
| 33170927 | One child was HIV infected and 11/51 (21·2%) were HIV exposed uninfected and 7/51 (13·7%) children had a recent or new diagnosis of tuberculosis. | 2020-11-10 |
| 33171100 | We present an integrated analysis of the clinical measurements, immune cells, and plasma multi-omics of 139 COVID-19 patients representing all levels of disease severity, from serial blood draws collected during the first week of infection following diagnosis. | 2020-11-10 |
| 33171364 | We report several findings on renal ultrasound with duplex Doppler not previously associated with COVID, specifically with FSGS, which in conjunction can be useful to both the radiologist and the clinician, potentially pointing them in the direction of this diagnosis and early treatment. | 2020-11-10 |
| 33171651 | Male sex (adjusted Odds Ratio (aOR): 3.04; 95% Confidence Interval (CI): 1.97-4.69), increasing age (aOR: 1.56; 95%CI: 1.36-1.79), symptoms at diagnosis (aOR: 6.05; 95%CI: 3.18-11.50), and underlying health conditions (aOR: 2.08; 95%CI: 1.31-3.31) were associated with hospitalization. | 2020-11-11 |
| 33171999 | To evaluate diagnostic accuracy of conventional radiography (CXR) and machine learning enhanced CXR (mlCXR) for the detection and quantification of disease-extent in COVID-19 patients compared to chest-CT. […] Further, readers had to assign confidence levels to their diagnosis. | 2020-11-11 |
| 33172342 | Accordingly, in this paper we highlight one such avenue-nanobodies-for potential utility in therapeutic and diagnostic interventions to combat COVID-19. | 2020-11-11 |
| 33172382 | Here, we review the recent nanotechnology techniques used for treating and testing SARS-CoV, MERS-CoV, and SARS-CoV-2, and potential therapeutic options for curing COVID-19. | 2020-11-11 |
| 33172592 | Experts reviewed the latest literature relating to the COVID-19 pandemic in critically ill patients, such as epidemiology, pathophysiology, phenotypes of infection, COVID-19 as a systematic infection, molecular diagnosis, mechanical ventilation, thromboprophylaxis, COVID-19 associated co-infections, immunotherapy, plasma treatment, catheter-related bloodstream infections, artificial intelligence for COVID-19, and vaccination. | 2020-11-11 |
| 33172767 | According to previous reports in high prevalence areas, CT screening may be useful in the diagnosis of COVID-19. […] This report examines the diagnostic efficacy of CT screening before admission to a hospital in Tokyo. | 2020-11-11 |
| 33173369 | The COVID-19 pandemic has presented challenges in symptomology identification, diagnosis, management and follow-up in common respiratory diseases, and in particular asthma. | 2020-11-11 |
| 33173391 | However, those guidelines lack practical recommendations on ways to manage triage and diagnosis expressly for new cancer patients. | 2020-11-11 |
| 33173449 | There is a need for alternative disinfection strategies and techniques that are adapted to the actual behavior of humans living in densely populated mega-cities. | 2020-11-11 |
| 33173496 | Anchoring to the diagnosis of COVID-19 may deter clinicians from considering other concurrent diagnoses and a poor outcome consequently. | 2020-11-11 |
| 33173753 | In addition atypical presentations may confuse and mislead physician to do different diagnostic procedures and interventions. […] We report a 6 years and half old boy with diarrhea, abdominal pain with first diagnosis acute abdomen due to acute appendicitis. […] At last diagnosis of pneumatosis intestinalis due to enterocolitis was confirmed. | 2020-11-11 |
| 33173808 | Although significant methodological advances have been made in the field of viral detection/diagnosis with 251 in vitro diagnostic tests receiving emergency use approval by the US-FDA, little progress has been made in identifying curative or preventive therapies. | 2020-11-11 |
| 33173844 | Contactless symptom tracking is essential for the diagnosis of COVID-19 cases that need hospitalization. […] The proposed multipurpose platform Coronario combines sensory information from different sources for a valid diagnosis following a dynamically adaptable protocol. | 2020-11-11 |
| 33174159 | However, diagnosis and treatment of HCC should not be delayed because of COVID-19 pandemic. […] For patients with confirmed or suspected to be infected with the novel coronavirus, diagnosis and treatment should be postponed until the virus is eliminated or they are confirmed as not being infected with it. | 2020-11-11 |
| 33174170 | The clinical use of our screening prediction model could improve the discrimination of SARS-CoV-2 related from other community-acquired pneumonias and thus help patient triage based on commonly used diagnostic approaches. | 2020-11-11 |
| 33174292 | Furthermore, technology is fundamental in connectivity, diagnostic evaluation, and security in order to create stable and useful patient-focused care. | 2020-11-11 |
| 33174360 | From a total of 992 valid questionnaires from 23 provinces in China, clinically significant anxiety symptoms were observed in 9.58% of respondents according to clinical diagnostic standards in China. | 2020-11-11 |
| 33174468 | While PD techniques are well described, there is uncertainty about how to determine the amount of PD to be prescribed toward a target dose. | 2020-11-11 |
| 33174617 | Well-designed, controlled clinical trials play a crucial role in the discovery of novel diagnostic and management strategies; however, these catastrophic circumstances pose unique challenges in initiating research studies at institutional, national, and international levels, highlighting the importance of a coordinated, collaborative approach. | 2020-11-11 |
| 33174632 | We enrolled male patients with a confirmed diagnosis of COVID-19 and performed a bedside ultrasound (US) examination of the scrotum, focused on findings of acute inflammation such as tunica albuginea thickening, enlargement and heterogeneous echogenicity of the testis, epididymis, or both, an abscess, scrotal wall edema, and hydrocele. […] A total of 142 patients with COVID-19 were enrolled in our study, and 32 (22.5%) patients had acute orchitis, epididymitis, or epididymo-orchitis on scrotal US imaging, according to the diagnosis criteria. | 2020-11-11 |
| 33174927 | Since a delay in diagnosis and treatment may influence prognosis, it is important that cancer centers and public health strategies reinforce care for non-COVID-19 patients to prevent potentially unnecessary deaths. | 2020-11-11 |
| 33175159 | The lag between the presentation of MIS-C and initial SARS-CoV-2 exposure, which may often be asymptomatic, together with the young age of our patient, makes this a challenging diagnosis. | 2020-11-11 |
| 33175565 | The development of diagnostic tests to identify SARS-CoV-2 or to detect anti-SARS-CoV2 antibodies in blood, of vaccines, and of preventive and curative treatments has been relying on intense activity of scientists in academia and industry. | 2020-11-11 |
| 33175702 | In doing so, it summarizes the origin of coronavirus, epidemiology, mode of transmission, diagnosis, treatment, prevention and control of the disease. […] Inadequacy of diagnostic facilities and limitations of clinical care and health care services were major constraints faced in treating COVID-19 infected people in Bangladesh. | 2020-11-11 |
| 33175707 | The state-level adjusted case fatality rate (aCFR) was estimated by dividing the cumulative number of deaths on a given day by the cumulative number confirmed cases 8 days before, which is the average time-lag between diagnosis and death. | 2020-11-11 |
| 33175709 | A 72-year-old man was admitted, with the diagnosis of COVID-19, ARDS, type-2 diabetes, diabetic nephropathy, renal insufficiency, and hypertension. | 2020-11-11 |
| 33175863 | Our logistic regression model in the development cohort considered demographics (age, sex, race/ethnicity), and pre-existing medical conditions and the Charlson Comorbidity Index (CCI) derived from ICD-10 diagnosis codes. […] Age, multimorbidity described with CCI, and a history of myocardial infarction or peripheral vascular disease were independently associated with mortality-no other individual comorbid diagnosis provided additional information. | 2020-11-11 |
| 33175911 | Diagnostic modalities were clinical chart review, radiology, microbiology, and histopathology which were assessed by two independent experts per modality. […] Clinical COD (CCOD) and contributing diagnosis were abstracted from the discharge letter. […] The main outcomes were alterations in CCOD and contributing diagnoses after MIA, and the contribution of each diagnostic modality. […] MIA found a new COD (1/5), a more specific COD (1/5), a less certain COD (1/5), or a contributing diagnosis to be the COD (2/5). […] MIA, especially histological examination, can add valuable new clinical information regarding the cause of death in COVID-19 patients, even in a high-resource setting with wide access to premortem diagnostic modalities. | 2020-11-11 |
| 33176009 | Nowadays, we have decidedly more sophisticated diagnostic tools than Virchow had, but many of the challenges that we are facing are the same as Virchow faced in the 19th century. | 2020-11-11 |
| 33176412 | It is our intention to discuss in logical terms the numerous papers that commendably reported adverse reactions attributable to OT, focusing our attention mainly to the techniques of administration and not to the simple contact of ozone with biological material. | 2020-11-12 |
| 33176530 | All patients were assessed for a one-month follow-up after the initial diagnosis of COVID-19. | 2020-11-12 |
| 33176693 | Here, we report the first patient cured of COVID-19 infection in Changsha, China, and the symptoms, diagnosis, treatment, and management of this patient are all described in this report. […] She tested positive for COVID-19 infection, a diagnosis which was supported by chest CT. […] This case describes the symptoms, diagnosis, treatment, and management of a patient cured of COVID-19 infection, which may serve as reference for future cases, while further studies are needed. | 2020-11-12 |
| 33176886 | Hypersensitivity to any of the substances going to be used in the study (Citric acid dextrosol 2.2% and unfractionated heparin); Previous diagnosis of coagulopathy or thrombophilia; Contraindication to the use of unfractionated heparin; Risk of citrate poisoning - (Lactate> 30 mg/dL, international normalized ratio > 2.5, Total bilirubin> 15 mg/dL); Pregnancy; Patients unlikely to survive for more than 24 hours. | 2020-11-12 |
| 33176927 | The COVID-19 pandemic and the consequent declaration of a state of alarm have required changes throughout the entire health system and diagnostic imaging departments are no exception. […] We also defined different care circuits for patients with COVID-19 and those without COVID-19, incorporating new technologies, adapting existing resources to the new scenario, and creating a circuit for the rapid diagnosis of COVID-19. | 2020-11-12 |
| 33177397 | As rapid and accurate diagnosis of COVID-19 is required to control the spread of this infectious disease, the current study evaluated three commercially available assays, including the TaqPath COVID-19 Combo kit, the cobas® SARS-CoV-2 test and the Rendu 2019-nCoV Assay kit, to establish diagnostic algorithms for clinical laboratories. […] Based on our evaluation, two SARS-CoV-2 diagnostic algorithms, one focusing on the manual assays and the other on the automatic platforms, were proposed. […] Our results provide valuable information that allow clinical laboratories to implement optimal diagnostic strategies for SARS-CoV-2 testing based on their clinical needs, such as test volume, turn-around time, and staff/resource limitations. | 2020-11-12 |
| 33177481 | This review aims to provide an update on the mechanisms involved in the development of the long-term sequelae of SARS-CoV-2 infection in the 3 main areas of lung injury, neuronal injury, and neurodegenerative diseases, including Alzheimer disease, Parkinson disease, and multiple sclerosis, and highlights the need for patient monitoring following the acute stage of infection with SARS-CoV-2 to provide a rationale for the prevention, diagnosis, and management of these potential long-term sequelae. | 2020-11-12 |
| 33177799 | Other publications did not provide sufficient information on the diagnostic criteria. […] We strongly highlight the need for adherence to the guidelines during a diagnostic and etiological workup, which could alter therapy. | 2020-11-12 |
| 33178714 | Our results validate the use of this direct RT-qPCR protocol as a safe alternative for SARS-CoV-2 diagnosis in the case of a shortage of reagents for RNA extraction, with minimal clinical impact. | 2020-11-12 |
| 33178771 | This study aimed to analyze the impact of new electronic communication tools in the diagnosis and treatment of patients with SARS-CoV-2 infection. […] In the test groups, the median time from diagnosis to the endpoint was 7.0 days [interquartile range (IQR), 3.8-10.8], compared with 10.0 days (IQR, 6.5-14.5) in the control group. | 2020-11-12 |
| 33178984 | Experts recognize the urgent need to develop a rapid point of care diagnostic tests. […] Ultrasonography is a widely established safe diagnostic imaging test for detecting various lung abnormalities. […] Ultrasound is sensitive to pleural and subpleural abnormalities, which suggests a great potential diagnostic role given the predilection for COVID-19 in peripheral subpleural regions.This paper reviews the current evidence and discusses the problems with specificity and scoring. | 2020-11-12 |
| 33178988 | The chest radiograph (CXR) is the predominant imaging investigation being used to triage patients prior to either performing a SARS-CoV-2 polymerase chain reaction (PCR) test or a diagnostic CT scan, but there are limited studies that assess the diagnostic accuracy of CXRs in COVID-19. […] To determine the accuracy of CXR diagnosis of COVID-19 compared with PCR in patients presenting with a clinical suspicion of COVID-19. […] The subset of this cohort that had CXR and PCR within 3 days of each other were included for further analysis for diagnostic accuracy. […] Compared to PCR as the reference test, initial CXR had a 61% sensitivity and 76% specificity in the diagnosis of COVID-19. […] Initial CXR is useful as a triage tool with a sensitivity of 61% and specificity of 76% in the diagnosis of COVID-19 in a hospital setting. […] Initial CXR is useful as a triage tool with a sensitivity of 61% and specificity of 76% in the diagnosis of COVID-19 in a hospital setting. | 2020-11-12 |
| 33179181 | The sum number of GI endoscopic procedures deceased significantly from 3,203,594 in 2019 to 1,512,619 in 2020, including 2,996,779 to 1,401,665 of diagnostic procedures and 206,815 to 110,954 of therapeutic procedures. | 2020-11-12 |
| 33179534 | The cutaneous lesions have potential for early diagnosis of COVID-19 and prevention of disease transmission. | 2020-11-12 |
| 33179954 | This pandemic has created an opportunity for international cooperation in working on transparency issues both in terms of sharing manufacturing details to make devices for the diagnosis and treatment of COVID-19 and in terms of clinical trials for therapies that could prove to be effective against the disease. | 2020-11-12 |
| 33180244 | Although previous data revealed characteristics of GI symptoms in COVID-19, for patients with only GI symptoms onset, their diagnostic process and potential transmission risk are still unclear. […] Patients with only GI symptoms of COVID-19 may take a longer time to present to healthcare services and receive a confirmed diagnosis. | 2020-11-12 |
| 33180423 | The number of cases has increased rapidly but laboratory diagnosis is limited. […] The serological test of SARS-CoV-2 can be used as an important supplement to the existing RT-PCR test for the specific and rapid diagnosis of COVID-19. | 2020-11-12 |
| 33180431 | For Coronavirus Disease 2019 (Covid-19) infection, clinical laboratories provide essential contributions in the diagnosis of infection, stage prognostication, and evaluation of disease severity. | 2020-11-12 |
| 33180449 | To investigate the clinical value of multi-index combined detection in the diagnosis of new coronavirus disease 2019 (COVID-19). […] Here we performed a study on the laboratory characteristics and explored their efficacy for diagnosis of the disease. […] The index of LYM, MON, RBC, HGB, PLT, TP, ALB, AST, GGT, and CRP can be used for the diagnosis of new COVID-19, and the indicators of LYM, MON, ALB, and CRP may be predictors of severe pneumonia. | 2020-11-12 |
| 33180450 | The reported 14.9% exposure/convalescent rate is lower than the reported 20% by the Department of Health and Governor Andrew Cuomo and may represent a better utilization of personal protective equipment, better hand washing techniques, and better disinfection procedures combined with strict social distancing. | 2020-11-12 |
| 33180807 | Hospital staff identified a need for diagnostic tests for symptomatic workers and patients. | 2020-11-12 |
| 33181098 | In this electronic health record network cohort study using data from 69 million individuals, 62 354 of whom had a diagnosis of COVID-19, we assessed whether a diagnosis of COVID-19 (compared with other health events) was associated with increased rates of subsequent psychiatric diagnoses, and whether patients with a history of psychiatric illness are at a higher risk of being diagnosed with COVID-19. […] We measured the incidence of and hazard ratios (HRs) for psychiatric disorders, dementia, and insomnia, during the first 14 to 90 days after a diagnosis of COVID-19. […] In patients with no previous psychiatric history, a diagnosis of COVID-19 was associated with increased incidence of a first psychiatric diagnosis in the following 14 to 90 days compared with six other health events (HR 2·1, 95% CI 1·8-2·5 vs influenza; 1·7, 1·5-1·9 vs other respiratory tract infections; 1·6, 1·4-1·9 vs skin infection; 1·6, 1·3-1·9 vs cholelithiasis; 2·2, 1·9-2·6 vs urolithiasis, and 2·1, 1·9-2·5 vs fracture of a large bone; all p<0·0001). […] The incidence of any psychiatric diagnosis in the 14 to 90 days after COVID-19 diagnosis was 18·1% (95% CI 17·6-18·6), including 5·8% (5·2-6·4) that were a first diagnosis. […] The incidence of a first diagnosis of dementia in the 14 to 90 days after COVID-19 diagnosis was 1·6% (95% CI 1·2-2·1) in people older than 65 years. […] A psychiatric diagnosis in the previous year was associated with a higher incidence of COVID-19 diagnosis (relative risk 1·65, 95% CI 1·59-1·71; p<0·0001). […] Survivors of COVID-19 appear to be at increased risk of psychiatric sequelae, and a psychiatric diagnosis might be an independent risk factor for COVID-19. | 2020-11-12 |
| 33181156 | Detailed information on glomerulonephritis diagnosis, kidney parameters, and baseline immunosuppression prior to infection were recorded, as well as clinical presentation, laboratory values, treatment, complications, and outcomes of COVID-19. | 2020-11-12 |
| 33181320 | The coronavirus disease 2019 (COVID-19) epidemic has been almost controlled in China under a series of policies, including “early diagnosis and early treatment”. | 2020-11-12 |
| 33181326 | A variety of techniques can be used to improve personal resilience. | 2020-11-12 |
| 33181329 | Molecular detection of SARS-CoV-2 using reverse transcription polymerase chain reaction (RT-PCR) forms the mainstay in screening, diagnosis and epidemiology of the disease. […] The recent availability of genomes of SARS-CoV-2 isolates motivated us to assess the presence and potential impact of variations in target sites of the oligonucleotide primers and probes used in molecular diagnosis. […] These included primers or probes sites which are used worldwide for molecular diagnosis as well as approved by national and international agencies. | 2020-11-12 |
| 33181447 | Our results show that major concerns presented in about half of the sentences are (1) PCR lab. test, diagnosis, and screening, (2) Closure of the education system, and (3) awareness actions about washing hands and facial mask usage. | 2020-11-12 |
| 33181454 | Patients hospitalized with COVID-19 were assessed in this single-center retrospective study. 189 patients, whose diagnosis was confirmed using real-time PCR, were included in the study. | 2020-11-12 |
| 33181473 | A strict compliance with these criteria and the continued oversight by external and independent control mechanisms are important to prevent ethically unjustified restrictions and discrimination against people with the diagnosis of a mental disorder during the COVID-19 pandemic. | 2020-11-12 |
| 33181697 | D-dimer is a marker of fibrinolysis and has been used as a diagnostic and prognostic marker in VTE among other diseases. […] VTE was diagnosed in 27 (23%) patients (mean time to diagnosis 14 ± 9 days). […] Within the first 7 days of hospitalization, peak D-dimer level of >2500 ng/mL and a rate of change exceeding 150 ng/mL/d were predictive of future diagnosis of VTE. […] Rise in D-dimer >2000 ng/mL within any 24 hour period through hospital day 10 had 75% sensitivity and 74% specificity for diagnosis of VTE.We found that both magnitude and rate of rise in d-dimer within the first 10 days of hospitalization are predictive of diagnosis of VTE but not mortality. | 2020-11-12 |
| 33181783 | SARS-CoV-2 serologic tests obtained early in the diagnostic process may help to narrow down the differential but does not distinguish between acute COVID-19 and MIS-C. | 2020-11-12 |
| 33181794 | The PIMS-ST was recently described, and the detailed quantitative pooled data will increase clinicians’ awareness, improve diagnosis, and promptly start treatment. | 2020-11-12 |
| 33182011 | The aim of this study was to determine aerosol transmission from patients with coronavirus infection using “COVID-19 traps” that included different untouched surfaces within them. 42 swab samples of 6 different surfaces placed in the rooms of 6 patients with a positive diagnostic of COVID-19 were analyzed with RT-PCR technique to evaluate the presence of the virus and its stability. | 2020-11-13 |
| 33182262 | Equally important is building local capacity to develop the tools required for rapid diagnosis of plant viruses. | 2020-11-13 |
| 33182336 | The simulation tool is a hybrid model that integrates discrete event and agent-based modeling techniques. | 2020-11-13 |
| 33182695 | Computed tomography (CT) plays an important role in the diagnosis of COVID-19. […] Their potential diagnostic ability was assessed with receiver operating characteristic (ROC)/area under the ROC curves (AUC) analysis. […] The semi-quantitative measurement outperformed the subjective assessment diagnostic ability (AUC = 85.6% for ICU treatment, 71.9% for intubation). | 2020-11-13 |
| 33182696 | ED visit characteristics and main diagnostic categories were assessed. […] During lockdown, significantly diminishing trends were shown for all diagnostic categories (between -40.8% and -73.6%), except influenza-like illness/COVID cases (+31.6%), Pulmonary embolism/deep vein thrombosis (+33.5%) and frequent users (+188.0%). | 2020-11-13 |
| 33182836 | and COVID-19 rapid diagnostics assays were key to the timely diagnosis of both infections, permitting appropriate treatment and patient care. | 2020-11-13 |
| 33183384 | Demographics, presenting symptoms, sick contact, triage vital signs, initial laboratory and chest X-ray results were analysed to develop a prediction model for COVID-19 diagnosis. […] A risk score for COVID-19 diagnosis achieved area under the receiver operating characteristic curve of 0.87 (95% confidence interval (CI) 0.82-0.92) in the development dataset and 0.85 (95% CI 0.78-0.92) in the validation dataset. | 2020-11-13 |
| 33183387 | This article explores how journal clubs have been approached in the past, both in person and more recently online, considers techniques for maintaining engagement in online teaching and proposes new approaches for future journal clubs. | 2020-11-13 |
| 33183522 | The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS). . . | 2020-11-13 |
| 33183963 | Various diagnostic tests utilizing different principles are currently under development for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Here, we evaluated the performance and features of three diagnostic assays: quantitative reverse transcription polymerase chain reaction (RT-qPCR), FilmArray Respiratory Panel (RP) v2.1, and the LUMIPULSE antigen test. […] Further, there were discrepant results using different types of diagnostic tests during the clinical course of prolonged viral shedding patient. | 2020-11-13 |
| 33184141 | Characteristics of laboratory findings of COVID-19 patients are of great significance for diagnosis and treatment. | 2020-11-13 |
| 33184170 | We collected clinical outcomes, laboratory findings, and diagnostic studies, including serial electrocardiograms, in all patients with MIS-C to identify those with first-degree atrioventricular block (AVB) during the acute phase and assess for predictive factors. | 2020-11-13 |
| 33184753 | Serological test is a valuable diagnostic tool for coronavirus disease 2019 (COVID-19). […] In conclusion, the eukaryotic expression spike proteins (rS1 and rS-RBD-mFc) are more suitable than the prokaryotic expression nucleocapsid proteins for serological diagnosis of SARS-CoV-2. | 2020-11-13 |
| 33184782 | Surgical oncology during phase 2 should be guaranteed by individual and distinct protocols and pathways between cancer patients and COVID-19 + patients with resources specifically addressed to the two distinct kind of patients to limit diagnostic/therapeutic interferences or slowdowns. | 2020-11-13 |
| 33184805 | The median number of cases with the diagnosis J21 (acute bronchitis) were significantly less in April 2020 vs. | 2020-11-13 |
| 33184940 | Nucleic acid detection combined with serum antibody of SARS-CoV-2 may be the best laboratory indicator for the diagnosis of SARS-CoV-2 infection and the phrase and predication for prognosis of COVID-19. | 2020-11-13 |
| 33184946 | The areas under receiver operating characteristic curves were calculated to estimate and compare the predictive values of different diagnostic markers. | 2020-11-13 |
| 33185181 | Asymptomatic frontline health workers were randomly selected from the University College Hospital Ibadan, Nigeria; venous blood samples were obtained from them, and the serum SARS-CoV-2 IgG level was determined using ELISA techniques. | 2020-11-13 |
| 33185672 | In this study we selected and reimplemented seven prediction models for COVID-19, which were derived from diverse cohorts and used different implementation techniques. | 2020-11-13 |
| 33185697 | Since there is so far no effective treatment or vaccination against the virus, early diagnostic recognition is of great importance. […] Due to the specific aspects of the infection, which mainly begins in the peripheral lung parenchyma, lung ultrasonography is suitable as a diagnostic imaging method to identify suspected cases as such in the early stages of the disease. […] This article summarizes the diagnostic potential of lung ultrasound with respect to screening and therapeutic decision-making in patients with suspected or confirmed SARS-CoV‑2 pneumonia. | 2020-11-13 |
| 33185718 | Among this rapidly growing population depression is a common and serious health problem; however, there are shortcomings in the diagnosis of depression and provision of psychotherapy. | 2020-11-13 |
| 33186172 | The aim of the study was to investigate chest computed tomography (CT) findings and the value of CT in the diagnosis in children with suspected coronavirus disease 2019 (COVID-19). | 2020-11-13 |
| 33186230 | PCR approaches form the basis for many high-sensitivity diagnostic tests and can supplement traditional contact tracing and surveillance strategies to define risk networks and transmission patterns. | 2020-11-13 |
| 33186406 | Several centers are developing reusable stop-gap respirators as alternatives to disposable N95 respirators during public health emergencies, using techniques such as 3D-printing, silicone moulding and plastic extrusion. | 2020-11-13 |
| 33186512 | Patients from 1 month to 19 years who met the MIS-C diagnostic criteria were included consecutively. | 2020-11-13 |
| 33186594 | Combining the asymptotic limit of our model with Bayesian hierarchical techniques, we provide US county level inferences for the reproduction number from cumulative case count data over July and August of this year. | 2020-11-13 |
| 33186810 | At the time of diagnosis, patients infected with Clade 1 viruses had significantly higher average viral loads in their upper airways relative to patients infected with Clade 2 viruses, independent of disease severity. | 2020-11-13 |
| 33187046 | Rash associated with a febrile illness often poses challenges in diagnosis. […] The clinical knowledge of pathogenesis, onset and characteristics of rash is therefore essential to make an early diagnosis and for successful management of the disease. […] We present herewith a case of a young man with acute febrile illness and rash which raised doubts with regards to the possible etiological diagnosis and necessitated detailed work up which revealed a diagnosis of COVID-19. […] The case is being highlighted as often the history and clinical presentation may seem to be obvious but an atypical uncommon presentation which in this case was a maculopapular rash may not fit the picture of a single etiological diagnosis according to the known medical literature. | 2020-11-13 |
| 33187119 | The primary goal of the greenhouse operation was to maximize net profit, by controlling the greenhouse climate and crop with AI techniques. | 2020-11-14 |
| 33187393 | In the university sector, longer delays for diagnostic measures were observed in comparison to non-university care. […] Despite delays in diagnostic procedures and outpatient appointments, only a minority of physicians foresee a major impact of COVID-19 on NET patient care. | 2020-11-14 |
| 33187475 | Timely and appropriate screening, diagnosis, and treatment are the key to achieve good outcomes. | 2020-11-14 |
| 33187528 | Performance characteristics of the rapid SARS-CoV-2 antigen detection test should be evaluated and compared with the gold standard real-time reverse transcription-polymerase chain reaction (RT-PCR) test for diagnosis of COVID-19 cases. | 2020-11-14 |
| 33187703 | The first diagnosis in Italy was on February 20, 2020, followed by the establishment of a light and a tight lockdown on February 23 and on March 8, 2020, respectively. | 2020-11-14 |
| 33187758 | It has been proven that lung ultrasound can be extremely valuable in the diagnosis and treatment of the disease, which could also minimize the number of exposed healthcare workers and equipment. | 2020-11-14 |
| 33187811 | Patients with hematologic malignancies had increased odds of COVID-19 infection compared with patients without hematologic malignancies for both all-time diagnosis (malignancy diagnosed in the past year or prior) (adjusted Odds ratio or AOR: 2.27 [2.17-2.36], p < 0.001) and recent diagnosis (malignancy diagnosed in the past year) (AOR:11.91 [11.31-12.53], p < 0.001), with strongest effect for recently diagnosed acute lymphoid leukemia (AOR: 31.03 [25.87-37.27], p < 0.001), essential thrombocythemia (AOR: 20.65 [19.10-22.32], p < 0.001), acute myeloid leukemia (AOR: 18.94 [15.79-22.73], p < 0.001), multiple myeloma (AOR: 14.21 [12.72-15.89], p < 0.001). | 2020-11-14 |
| 33188011 | During the first 3 months of 2020, as the COVID-19 pandemic developed, it was noticed that requests from primary care for investigations were decreasing, including those that form part of the diagnostic process for cancers. […] If this phenomenon is widespread it may have an impact on diagnosis of major conditions, particularly cancers and tuberculosis. | 2020-11-14 |
| 33188461 | The patients who underwent surgical treatment longer than 67 days after diagnosis had a significantly increased risk of death (HR, 1.189; 95% confidence interval [CI], 1.122-1.261; P < 0.0001). […] Increasing TTS is an independent predictor of survival for patients with HNSCC and should be performed within 67 days after diagnosis to achieve optimal survival outcomes. | 2020-11-14 |
| 33188533 | To describe our experience concerning lung ultrasound (LUS) in the pediatric emergency clinic, and to investigate the diagnostic value of LUS in coronavirus disease-2019 (COVID-19). | 2020-11-14 |
| 33188626 | Patients with the diagnosis of COVID-19 who were admitted to our hospital between March and June 2020 were retrospectively analyzed. | 2020-11-14 |
| 33188933 | Management and control of coronavirus disease 2019 (COVID-19) relies on reliable diagnostic testing. […] To evaluate the diagnostic test accuracy (DTA) of nucleic acid amplification tests (NAATs) for the diagnosis of coronavirus infections. […] Risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 tool. | 2020-11-14 |
| 33189137 | Several molecular kits are available for SARS-CoV-2 diagnosis, mostly lacking of proper clinical evaluation due to the emergency caused by COVID19 pandemia, particularly at developing countries like Ecuador. […] We carried out an evaluation of the clinical performance of “AccuPower SARS-CoV-2 Real Time RT-PCR kit” (Bioneer, South Korea) for SARS-CoV-2 diagnosis using 2019-nCoV CDC EUA kit (IDT, USA) as a gold standard. 48 clinical specimens were included on the study, 38 tested SARS-CoV-2 positive and 10 SARS-CoV-2 negative for 2019-nCoV CDC EUA kit. […] Proper clinical performance evaluation studies from government agencies at developing countries should be mandatory prior to clinical use authorization of SARS-CoV-2 diagnosis kits, particularly when those kits lack of either FDA or its country of origin clinical use authorization, to prevent the distribution of low quality products that may have a negative impact of COVID19 surveillance at developing countries. | 2020-11-15 |
| 33189517 | Data collected included demographics, ESI, diagnosis, consultations ordered, bedside procedures, and inpatient procedures within 48 h. | 2020-11-15 |
| 33189776 | Here we have used artificial intelligence (AI) and pattern recognition techniques for initial screening of FDA approved pharmaceuticals and nutraceuticals to target this E protein. | 2020-11-15 |
| 33189872 | To our knowledge no previous study has assessed the performance of a rapid antigen diagnostic immunoassay (RAD) conducted at the point of care (POC). […] We evaluated the Panbio™ COVID-19 Ag Rapid Test Device for diagnosis of coronavirus 2019 disease (COVID-19) in symptomatic patients (n = 412) attending primary healthcare centres. […] The Panbio™ COVID-19 Ag Rapid Test Device performed well as a POC test for early diagnosis of COVID-19 in primary healthcare centres. | 2020-11-15 |
| 33189890 | The high proportion of asymptomatic COVID-19 patients and independent factors for mortality suggest that early diagnosis and treatment of COVID-19 patients in LTCFs may be effective in saving lives. | 2020-11-15 |
| 33190021 | Thirteen (41%) had active cancer, with 6 (19%) on cancer therapy within 4 weeks of COVID-19 diagnosis. | 2020-11-15 |
| 33190025 | Half of PE was diagnosed at COVID-19 diagnosis. | 2020-11-15 |
| 33190102 | Computed Tomography is an essential diagnostic tool in the management of COVID-19. […] Considering the large amount of examinations in high case-load scenarios, an automated tool could facilitate and save critical time in the diagnosis and risk stratification of the disease. […] The diagnostic performance was then evaluated and compared to experienced radiologists on an independent testing dataset. […] Diagnostic performance metrics were calculated using Receiver Operating Characteristics (ROC) analysis. […] Accurate diagnosis of COVID-19 using a basic deep learning approach is feasible using open-source CT image data. | 2020-11-15 |
| 33190302 | Moreover, IgG-, IgM- and IgA-specific antibodies against SARS-CoV-2 can be detected in most patients, along with the viral RNA, forming the basis for assays that aid in patient diagnosis. | 2020-11-15 |
| 33190387 | Two additional immunohistology techniques were developed in order to (i) detect a SARS-CoV-2 recombinant fusion nucleoprotein by using a specific antibody and (ii) study fractalkine expression induced by activated endothelium because this molecule is well known to be elevated in patients with severe cytokine release syndrome. […] Even if the clinical presentation, laboratory markers, and cardiac imaging techniques strongly suggested fulminant myocarditis, histology and immunohistology were not fully consistent with this diagnosis according to the Dallas criteria. | 2020-11-15 |
| 33190397 | In our cases, patients never had a TE diagnosis before and did not report previous evident hair loss. | 2020-11-15 |
| 33190400 | Early diagnosis and identification of potential critical cases for timely treatment are crucial for COVID-19 patients. […] The aim of this study was to analyze the diagnostic and prognostic implications of WBC and cell population data (CPD) abnormalities related to COVID-19 at disease onset. […] The ROC curve analysis showed good performance for lymphocyte counts in predicting COVID-19 diagnosis (AUC = 0.858), for neutrophil counts in predicting admission for COVID-19 (AUC = 0.744) and for monocytes volume in predicting COVID-19 diagnosis (AUC = 0.837). […] WBC counts and CPD parameters at disease onset in COVID-19 patients can improve diagnostic characterization and aid in the discrimination between severe and nonsevere presentations. | 2020-11-15 |
| 33190816 | Time to the diagnosis of DVT from admission was analyzed using log-rank test and Kaplan-Meier plots. | 2020-11-16 |
| 33191372 | The fever resolved a few days after favipiravir discontinuation, demonstrating the accuracy of the diagnosis. | 2020-11-16 |
| 33191476 | Our study based on an ensemble deep transfer learning system with different pre-trained CNNs architectures can work well on a publicly available dataset of CT images for the diagnosis of COVID-19 based on CT scans. | 2020-11-16 |
| 33191578 | Overall, a diagnostic specificity of 100.0% and sensitivity of 98.31% were achieved, and the functionality with every species included in this study could be demonstrated. | 2020-11-16 |
| 33191600 | Use of ACEI or ARB was not associated with a heightened susceptibility for a positive diagnosis of COVID-19. | 2020-11-16 |
| 33191905 | Biopsy of the lesion was performed, and histopathology result was consistent with the diagnosis of DLE. | 2020-11-16 |
| 33192159 | In some instances, CT scan based diagnosis has been found to have better sensitivity than RT-PCR, which is currently the gold standard for COVID-19 diagnosis. | 2020-11-16 |
| 33192209 | Wastage occurs at all stages from harvesting to the consumer, calling for advanced techniques of food preservation. […] Preservation methods include thermal, electrical, chemical and radiation techniques. […] Here, we review the advanced food preservation techniques, with focus on fruits, vegetables, beverages and spices. | 2020-11-16 |
| 33193009 | Anosmia and hyposmia (reduced sense of smell) affect a majority of patients years before the onset of cognitive or motor symptoms, establishing olfactory dysfunction as early biomarker that can enable earlier diagnosis and preventative treatments. | 2020-11-16 |
| 33193350 | A recent study has demonstrated that influenza-infected patients are at highest risk of having MI during the first seven days of diagnosis. | 2020-11-16 |
| 33193552 | The increasing number of casualties underlines an urgent need for the rapid delivery of therapeutics, prophylactics such as vaccines, and diagnostic reagents. | 2020-11-16 |
| 33193948 | the aim of this work is to evaluate the contribution of thoracic computed tomography (CT) in the diagnosis of COVID-19 in Guinea. this was a retrospective study with data recorded over a 2 Month period. […] Not included are those who did or did not perform a chest CT scan after confirmation of the diagnosis by RT-PCR. […] The reverse transcriptase PCR (RT-PCR) test was later positive in 33 patients (94.28%) and negative in 2 (5.71%). it is noted from this study that chest computed tomography is a critical tool in the rapid diagnosis of COVID-19 infection. […] Its systematization in all patients suspected in our dispute, would facilitate diagnosis while waiting for confirmation by RT-PCR and would limit the loss of cases. | 2020-11-16 |
| 33193950 | Tuberculous neuroretinis, a relatively rare manifestation of extra-pulmonary tuberculosis, is characterized by optic disc edema, peripapillary and macula swelling, with hard exudates forming a partial or complete ‘macular star’ While the disease may present a diagnostic challenge for Ophthalmologists, prognosis is usually good, with proper management. | 2020-11-16 |
| 33193953 | We report the case of a 36-year-old patient suspected of COVID-19 and in whom a second acquisition of chest CT was necessary to remove false ground-glass opacities that erroneously supported the diagnosis of COVID-19. | 2020-11-16 |
| 33193961 | We conducted participatory rural appraisal techniques to enable market vendors and clients to visualize two-meter distances and provided a prototype hand-washing facility that was foot operated. | 2020-11-16 |
| 33194071 | False negative results of NAT inconsistent with clinical diagnosis are often reported. | 2020-11-16 |
| 33194126 | Due to the COVID-19 pandemic, the FDA was forced to bypass normal protocol and issue Emergency Use Authorization for diagnostic testing. […] As a result, we have seen an explosion in the number of available molecular diagnostic tests developed by various private enterprises. […] Our case reports of an 85-year-old female who was suffering from a multitude of co-morbidities and underwent three different molecular diagnostic tests in a short timeframe. | 2020-11-16 |
| 33194152 | Careful revision of baseline hematologic data at diagnosis can predict the severity of illness and help clinicians tailoring the approach and management of patients whose condition can be guarded or critical. | 2020-11-16 |
| 33194204 | However, severe acute respiratory syndrome coronavirus 2 testing was negative and further questioning of these adolescents and their parents revealed a history of vaping marijuana-related products leading to the eventual diagnosis of e-cigarette, or vaping, product use-associated lung injury. | 2020-11-16 |
| 33194447 | This approach has the potential to help radiologists and frontline physicians by providing more timely and accurate diagnosis. | 2020-11-16 |
| 33194449 | They then fill out a questionnaire consisting of items concerning behavior intention and adapted from the Risk Behavior Diagnosis Scale. | 2020-11-16 |
| 33194477 | The arrival time of coronavirus disease COVID-19 tests (PCR and/or rapid diagnostic kits showing antibodies) to the hospital was questioned; seven people (5.83%) stated that tests were not performed at their hospitals. | 2020-11-16 |
| 33194503 | Septic arthritis remains an orthopaedic emergency that requires prompt diagnosis and management. […] During the COVID-19 ‘lock-down’ period (March 2020 to June 2020), we prospectively followed the presentation, diagnosis, management and outcome of a total of six patients who presented with confirmed native joint septic arthritis. […] All six patients underwent initial medical management of their septic arthritis following their diagnostic aspiration, which involved serial closed-needle aspirations and antibiotic therapy as advised by our microbiology team. | 2020-11-16 |
| 33194697 | In patients with cancer treated with ICI who present at the emergency department with respiratory symptoms during the COVID-19 pandemic, correct diagnosis can be challenging. […] We summarize the clinical, radiological features as well as additional investigations of both entities, and suggest a diagnostic algorithm for distinction between the two. | 2020-11-16 |
| 33194872 | Diagnostic errors are a serious problem in healthcare. […] The diagnostic process is highly susceptible to cognitive bias and the current COVID-19 pandemic may cause normally accurate healthcare workers to make incorrect decisions. […] This case highlights the risk of anchoring bias and the importance of carefully assessing diagnostic processes during the COVID-19 pandemic. […] COVID-19 can disrupt the healthcare system and clinical environment and affect diagnosis due to anchoring bias.Healthcare providers should carefully check the COVID-19 illness script to reduce diagnostic errors.Healthcare providers should prepare and practice a diagnostic debiasing strategy during the COVID-19 pandemic. | 2020-11-16 |
| 33194874 | The coronavirus disease 2019 (COVID-19) pandemic has made it difficult for physicians to follow their usual diagnostic processes. […] To avoid missing a diagnosis, physicians must practice zero-based thinking, regardless of COVID-19 concerns, and not be distracted from the patient’s core problems. […] During the COVID-19 pandemic, significant diagnostic errors can occur because physicians are so concerned about COVID-19 that they may ignore other diagnoses.To avoid missing a life-threatening condition during the COVID-19 pandemic, physicians must consider zero-based thinking, regardless of COVID-19 concerns, and not be distracted from the patient’s core problems.Measuring vital signs after a short walk can be helpful for investigating suspected pulmonary thromboembolism. | 2020-11-16 |
| 33194949 | As of mid-March, Taiwan had high rates of diagnostic testing (688.5 tests per million citizens) with a lower infection rate (49 cases, 2.1 cases per million people). | 2020-11-16 |
| 33194964 | The emergence of a new coronavirus (SARS-CoV-2) outbreak represents a challenge for the diagnostic laboratories responsible for developing test kits to identify those infected with SARS-CoV-2. […] The findings of this patent search show that an increasing number of materials and diagnostic tests for the coronavirus are being produced to identify infected individuals and combat the growth of the current pandemic; however, there is still a question in relation to the reliability of the results of these tests. | 2020-11-16 |
| 33195304 | In addition to modeling the stages of disease progression along with diagnostic testing, we have also created a treatment algorithm that considers age, comorbidities, clinical presentation, and disease progression to suggest drug classes or treatment modalities. | 2020-11-16 |
| 33195319 | While literature on the disease is rapidly accumulating, an integrated, multinational perspective on clinical manifestations, immunological effects, diagnosis, prevention, and treatment of COVID-19 can be of global benefit. | 2020-11-16 |
| 33195849 | 3D reconstruction has a significant role in the diagnosis and management of COVID-19 patients. […] The quality and reliability of 3D reconstructions allow the clinician to make a quick and efficient diagnosis and avoid an eventual false negative (produced by the RT-PCR test). | 2020-11-16 |
| 33196035 | With World Health Organization (WHO) declaring COVID-19 as pandemic, we deemed it necessary to provide a detailed review of coronaviruses discussing their history, current situation, coronavirus classification, pathogenesis, structure, mode of action, diagnosis and treatment, the effect of environmental factors, risk reduction and guidelines to understand the virus and develop ways to control it. | 2020-11-16 |
| 33196057 | Following this, various aspects of diagnosis and therapy and the relationship to artificial intelligence are presented along with a future projection of an ideal deployment of artificial intelligence in a pandemic. | 2020-11-16 |
| 33196119 | Participants of the ParkLink study with the clinical diagnosis of Parkinson’s disease or parkinsonism and people anonymously matched (ratio 1:10) for sex, age, district, and Charlson Index were included. | 2020-11-16 |
| 33196279 | Another challenge is the decrease in diagnostic support for evaluating patients compared with a pre-COVID-19 world. […] This loss of diagnostic and therapeutic support has had an emotional toll on patients and their caregivers. | 2020-11-16 |
| 33196593 | The aim of this study was to perform a meta-analysis assessing the diagnostic yield of computed tomography (CT) for the identification of coronavirus disease 2019 (COVID-19) using repeated reverse transcriptase polymerase chain reaction testing or confirmed true-negative state as reference standard. […] Pooled sensitivity, specificity, and diagnostic odds ratios of CT for COVID-19 identification were computed. […] Pooled sensitivity, specificity, and summary diagnostic odds ratio of CT were 82% [95% confidence interval (CI), 79%-84%], 68% (95% CI, 65%-71%), and 18 (95% CI, 9.8-32.8). | 2020-11-16 |
| 33196625 | A diagnosis of SARS-CoV-2 (RT-PCR or Ab+) was associated with being from a noncaucasoid background, P = 0.015; having a diagnosis of diabetes, P = 0.028 and a history of allograft rejection, P < 0.01. […] Compared with the RT-PCR+ cohort, patients with serological-proven infection alone were more likely to be receiving tacrolimus monotherapy, P < 0.01, and less likely to have a diagnosis of diabetes, P = 0.012. | 2020-11-16 |
| 33197261 | Nineteen children of median age 9.1 years fulfilled the definition of PIMS-TS and were managed within an MDT framework: 5/19 were female; 14/19 were of Black, Asian or minority ethnicity; 9/19 also fulfilled diagnostic criteria for complete or incomplete Kawasaki disease (KD). […] We observed significant diagnostic equipoise using a current definition of PIMS-TS, overlapping with KD. | 2020-11-16 |
| 33197423 | Based on the complexity of the problem and the need for interdisciplinary research, this study presents a conceptual model that addresses the integration of engineering controls, design strategies and, air disinfection techniques required to achieve a better IAQ. | 2020-11-16 |
| 33197638 | Our goal was to create an automated and quantitative measure of ground-glass opacities from lung CT images that could be used clinically for diagnosis, triage and research. | 2020-11-16 |
| 33197713 | While reverse transcriptase-polymerase chain reaction (RT-PCR) test is the most commonly utilized test and considered the current gold standard for diagnosis, the role of chest imaging has been highlighted by several studies demonstrating high sensitivity of computed tomography (CT). […] Many have suggested using CT chest as a first-line screening tool for the diagnosis of COVID-19. […] However, with advancement of laboratory testing and challenges in obtaining a CT scan without significant risk to healthcare providers, the role of imaging in diagnosis has been questioned. […] In this review, we highlight the current evidence on various modalities in thoracic imaging for the diagnosis of COVID-19 and describe an algorithm on how to use these resources in an optimal fashion in accordance with the guidelines and statements released by major imaging societies. | 2020-11-16 |
| 33197843 | The causal association between Guillen-Barre-Syndrome and COVID-19 is uncertain yet, but neurologists should be aware of early diagnosis and treatment of acute polyradiculoneuropathy which may cause fatal dysautonomia and respiratory failure in the context of COVID19 pandemic. | 2020-11-16 |
| 33197879 | The questionnaire comprised items on typical COVID-19 symptoms, age range, gender, employment in patient-facing healthcare, housing status, postal code, previous illnesses, permanent medication, vaccination status, results of reverse transcription polymerase chain reaction (RT-PCR) and antibody tests for COVID-19 diagnosis, and consequent COVID-19 treatment if applicable. […] When COVID-19 diagnosis was based on restrictive symptom criteria (ie, presence of 4 out of 7 symptoms) or a positive RT-PCR test, a statistically significant association was found solely for statins (odds ratio 0.28, 95% CI 0.1-0.78). | 2020-11-16 |
| 33198199 | This case report illustrates the value of a multimodal approach capitalizing on advanced brain-imaging and bedside electrophysiology techniques to improve prognosis accuracy in this complex and new aetiology. | 2020-11-17 |
| 33198368 | In this study, IV was associated with a lower probability of COVID-19 diagnosis. | 2020-11-17 |
| 33198412 | Diagnostic and pharmacological findings in this field of study are strongly warranted to address the neurological and psychological symptoms of COVID-19. | 2020-11-17 |
| 33198594 | The final construct was built based on the bioinformatics analysis, which could help to develop an antigen-capture system for the early diagnosis of SARS-CoV-2. | 2020-11-17 |
| 33198681 | This first case illustrated the difficulty of COVID-19 diagnosis in patients with isolated digestive symptoms in first trimester of pregnancy that could be confused with gravida hyperemesis. | 2020-11-17 |
| 33198751 | Diagnostic bronchoalveolar lavage (BAL) was performed in 33 adult patients with SARS-CoV-2 infection by real-time PCR on nasopharyngeal swab admitted to the Intensive care unit (ICU) (n = 28) and to the Intermediate Medicine Ward (IMW) (n = 5). | 2020-11-17 |
| 33198780 | One hundred-four (50%) received a final diagnosis of SARS-CoV-2 infection. | 2020-11-17 |
| 33198786 | The methodological quality of the included studies was assessed by Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2). | 2020-11-17 |
| 33198858 | The clinical features, diagnosis and treatment were summarized, and experience in the treatment of COVID-19 was shared. | 2020-11-17 |
| 33198859 | The diagnosis and treatment process of one elderly patient with CAP accompanied by COVID-19 who was admitted to COVID-19 Treatment Center of Liaoning Province on February 7, 2020 were reviewed. […] The experience of treatment by analyzing the characteristics of such type of patients during diagnosis and treatment were summarized. ) of 95 mmHg (1 mmHg = 0.133 kPa), and diffuse interstitial pneumonia in both lungs indicated by chest CT, of which the majority were ground glass-like and fibrous lesions. | 2020-11-17 |
| 33199136 | Different drugs and vaccines are under clinical trials and some rapid and effective diagnostic tools are also under development. […] In this review, we have highlighted the current epidemiology through infographics, disease transmission and progression, clinical features and diagnosis and possible therapeutic approaches for COVID-19. | 2020-11-17 |
| 33199310 | There is a lack of information on the clinical profile of patients with suspected COVID-19 in primary care, and controversy on the effectiveness of rapid serologic tests in the diagnosis and surveillance of the disease. | 2020-11-17 |
| 33199326 | Given the uncertain spectrum of COVID-19 presentations and variable sensitivity of laboratory tests for SARS-CoV-2, there is a risk that, without a high index of suspicion, alternative aetiologies may be overlooked while pursuing a diagnosis of COVID-19. | 2020-11-17 |
| 33199339 | Given the presentation during the coronavirus pandemic, a computed tomography pulmonary angiography was performed in line with the diagnostic pathway for COVID-19, which incidentally showed a significant pneumomediastinum and pneumopericardium. | 2020-11-17 |
| 33199447 | As genetic services are asked to gradually resume, a roadmap is needed to ensure clinical care decisions for at-risk patients are transparent and equitable, that postponed care is resumed and that patients with or waiting for a genetic diagnosis are not disproportionately affected or abandoned.The purpose of this document is to highlight the guiding ethical principles and stakeholder considerations in resuming genetic services to help guide the competing needs going forward of both limiting exposures while maintaining high-quality care. | 2020-11-17 |
| 33199671 | Especially, hsa-miR-15b-5p and hsa-miR-195-5p showed a large difference in expression, indicating that they may potentially be diagnostic biomarkers for SARS-CoV-2 infection. | 2020-11-17 |
| 33199713 | We show that IgG detection alone is insufficient for the diagnosis of active or cured COVID-19. […] IgM detection has a limited diagnostic value. | 2020-11-17 |
| 33199801 | Here we show, for the first time, that Deep Learning techniques can be used to handle LMS users’ interaction data and form a novel predictive model, namely DeepLMS, that can forecast the quality of interaction (QoI) with LMS. | 2020-11-17 |
| 33199859 | We propose a modelling approach that combines four computational techniques merging statistical, inference and artificial intelligence tools. | 2020-11-17 |
| 33199970 | The biggest issues for diagnosis COVID-19 is not established apart from Real-time reverse transcriptase polymerase chain reaction (RT-PCR). | 2020-11-17 |
| 33200006 | Reverse transcriptase polymerase chain reaction (RT-PCR) of specimens from the upper and/or lower respiratory tract is the gold standard for the diagnosis of COVID-19. […] Radiology and especially high-resolution computed tomography (HRCT) are important for diagnosis and follow-up. | 2020-11-17 |
| 33200065 | Present study using optimization techniques try to find the general functional form for the variables like identification of the carrier’s and testing effort. | 2020-11-17 |
| 33200109 | Diagnostic evaluation revealed a new cardiomyopathy, left ventricular thrombus, and mid right coronary artery thrombosis. | 2020-11-17 |
| 33200114 | Focusing only on COVID-19 may lead to delayed diagnosis and therapy in patients with “traditional diseases”. | 2020-11-17 |
| 33200414 | Such rapid spread is predominantly attributed to the poor diagnosis and its asymptomatic transmission. […] In the absence of treatment regime, timely diagnosis is the best available remedy that can restrict its spread. […] An early diagnosis of COVID-19 is critical for determining the line of treatment and preventing long term complications in the infected subject. […] In this article, the limitations of available diagnostic procedures have been elaborated and plausible combination approach has been advised. | 2020-11-17 |
| 33200675 | The conclusion is that the pandemic cannot be approached by standardised analytical techniques, because it, like other wicked problems, represents a unique challenge and because all possible solutions may lead to unknown negative consequences. | 2020-11-17 |
| 33200686 | Limited molecular laboratory capacity in resource constrained settings is a challenge in the diagnosis of the ever-increasing cases and the overall management of the disease. | 2020-11-17 |
| 33200752 | The aim of this study is to point out the changes and possible delay in diagnosis or treatment of malignancies and an added risk of COVID-19 exposure emerging from these interventions, as well as to underline the increase of surgical demand once the pandemic measures are eased. | 2020-11-17 |
| 33200836 | Fourteen days since symptom onset, we did not find any significant difference between the three techniques in terms of sensitivities. | 2020-11-17 |
| 33200993 | Data analysis will include parametric and nonparametric techniques, focusing on primary outcomes (ie, cravings, anxiety, and depressive symptoms) and metrics of use, including the number of subscribers and user satisfaction. | 2020-11-17 |
| 33201063 | The coronavirus disease 2019 global pandemic is reshaping our understanding of medicine, including the diagnostic approach to common medical presentations. […] We describe a novel case of a 3-year-old male with a clinical diagnosis of Henoch-Schonlein Purpura vasculitis with concurrent SARS-CoV-2 infection. | 2020-11-17 |
| 33201643 | A diagnosis of coronavirus disease 2019 (COVID-19) was assumed. […] Due to limited testing capacity, the diagnosis was not confirmed. | 2020-11-17 |
| 33201740 | The generation of these emotions has seriously affected the normal order of outpatient treatment and has led to many children not receiving an accurate diagnosis or proper treatment. | 2020-11-17 |
| 33201768 | The currently reported rates of cardiac involvement of COVID-19 makes myocarditis a risk, and physicians who clear athletes for participation in sport as well as sideline personnel should be versed with the diagnosis, management, and clearance of athletes with suspected myocarditis. | 2020-11-17 |
| 33201863 | We also describe the associated diagnostic and therapeutic challenges. […] CONCLUSIONS This case highlights the presence of significant COVID-19-related hemostatic disturbances and the importance of associated diagnostic and therapeutic challenges. […] Early diagnosis by keeping a high index of suspicion and prompt treatment is vital to avoid adverse outcomes and increased mortality. | 2020-11-17 |
| 33201872 | Artificial intelligence (AI) in radiology has improved diagnostic performance and shortened reading times of coronavirus disease 2019 (COVID-19) patients’ studies. […] We analyzed the diagnostic yield of the relevant CT variables using the area under the ROC curve (area under the curve [AUC]). […] The highest diagnostic yield of the assessed CT variables for mortality was the percentage of total opacity (threshold >51%; AUC = 0.88, sensitivity = 74%, and specificity = 91%). […] The AI-calculated CT severity score and total opacity percentage showed good diagnostic accuracy for mortality and met MV criteria. | 2020-11-17 |
| 33201919 | Among them, chest X-ray imaging technology is a valuable imaging diagnosis method. […] The use of computer-aided diagnosis to screen X-ray images of COVID-19 cases can provide experts with auxiliary diagnosis suggestions, which can reduce the burden of experts to a certain extent. […] In this study, we first used conventional transfer learning methods, using five pre-trained deep learning models, which the Xception model showed a relatively ideal effect, and the diagnostic accuracy reached 96.75%. […] In order to further improve the diagnostic accuracy, we propose an efficient diagnostic method that uses a combination of deep features and machine learning classification. […] It implements an end-to-end diagnostic model. […] The experimental results show that the diagnostic accuracy of Xception + SVM is as high as 99.33%. […] Compared with the baseline Xception model, the diagnostic accuracy is improved by 2.58%. […] Compared with related research, our proposed method has higher classification accuracy and efficient diagnostic performance. […] Overall, the proposed method substantially advances the current radiology based methodology, it can be very helpful tool for clinical practitioners and radiologists to aid them in diagnosis and follow-up of COVID-19 cases. | 2020-11-17 |
| 33202218 | At present, there is still no standardized diagnostic criteria and treatment regimen for PMIS, while the etiology and pathogenesis still remain unclear. | 2020-11-17 |
| 33202292 | IR procedural volumes were compiled, stratified by location and compared with Diagnostic Radiology (DR) volumes during the same timeframe. | 2020-11-17 |
| 33202303 | Simple laboratory variables are helpful for rapid diagnosis on admission and hierarchical management of COVID-19 patients. | 2020-11-17 |
| 33202888 | Accurate and immediate diagnosis of infectious agents and symptoms is a key to control the outbreak of these diseases. […] Rapid advances in complementary metal-oxide-semiconductor (CMOS) technology offers great advantages like high accuracy, high throughput and rapid measurements in biomedical research and disease diagnosis. […] These features as well as low cost, low power and scalability of CMOS technology can pave the way for the development of powerful devices such as point-of-care (PoC) systems, lab-on-chip (LoC) platforms and symptom screening devices for accurate and timely diagnosis of infectious diseases. | 2020-11-18 |
| 33203440 | Patients will be excluded if they have pre-existing cognitive impairment, pre-existing psychotic diagnosis or are not expected to survive post-hospital discharge. | 2020-11-18 |
| 33203496 | To compare sensitivity of specimens for COVID-19 diagnosis, we tested 151 nasopharyngeal/midturbinate swab pairs from 117 COVID-19 inpatients using reverse-transcriptase polymerase chain reaction (RT-PCR). | 2020-11-18 |
| 33204229 | The proposed HDS has been compared against recent techniques. | 2020-11-18 |
| 33204563 | COVID-19 is an emergent lung disease that is affecting the population worldwide; many other noninfectious diseases can mimic its presentations and laboratory characteristics; the importance of having a broad differential diagnosis especially in causing confusion during pandemic times is valuable in the management of patients with such presentations, such as EVALI, and glucocorticoids will be indicated in this circumstances. | 2020-11-18 |
| 33204610 | In the diagnosis of SIADH it is important to ascertain the euvolemic state of extra cellular fluid volume, both clinically and laboratory measurement. | 2020-11-18 |
| 33204762 | We concomitantly evaluated an innovative molecular diagnostic technology technique, the BioFire, FilmArray Pneumonia Panel plus (FA-pneumo) assay, to identify these coinfections at an early stage, and its concordance with conventional culture. copies/mL bacterial nucleic acids. | 2020-11-18 |
| 33204821 | Information technology was applied in several aspects, such as increasing the accuracy of diagnosis, early detection, ensuring healthcare providers’ safety, decreasing workload, saving time and cost, and drug discovery. […] We categorized these applications into four core topics, including diagnosis and prediction, treatment, protection, and management goals, which were confirmed by five experts. | 2020-11-18 |
| 33204938 | In the context of COVID-19, IoT-enabled/linked devices/applications are utilized to lower the possible spread of COVID-19 to others by early diagnosis, monitoring patients, and practicing defined protocols after patient recovery. […] This paper surveys the role of IoT-based technologies in COVID-19 and reviews the state-of-the-art architectures, platforms, applications, and industrial IoT-based solutions combating COVID-19 in three main phases, including early diagnosis, quarantine time, and after recovery. | 2020-11-18 |
| 33205046 | = 46) admitted to our 34-bed ICU between March 24, 2020, and May 25, 2020, and identified six patients that met the diagnosis of invasive pulmonary aspergillosis according to previously established definitions. | 2020-11-18 |
| 33205053 | Symptom overlap between COVID-19 and lung cancer may complicate diagnostic evaluation. […] We aimed to investigate the incidence, symptoms, differential diagnosis, and outcomes of COVID-19 in patients with lung cancer. | 2020-11-18 |
| 33205450 | None were hospitalised at diagnosis, but one was later admitted for peri-myocarditis. | 2020-11-18 |
| 33205743 | Likewise, the repurposing of antimalarials for the treatment of COVID-19 and a shift in focus from the production of malaria rapid diagnostic tests to COVID-19 rapid diagnostic tests are causes for concern in malaria-endemic regions. | 2020-11-18 |
| 33205821 | For 12 CVDs (stable angina; unstable angina; myocardial infarction; sudden cardiac death or cardiac arrest; unheralded coronary death; heart failure; transient ischaemic attack; ischaemic stroke; subarachnoid haemorrhage; intracerebral haemorrhage; peripheral arterial disease; abdominal aortic aneurysm), we estimated prevalence, incidence, and 1-year mortality post-diagnosis, comparing homeless and housed groups. […] CVD in homeless individuals has high prevalence, incidence, and 1-year mortality risk post-diagnosis with earlier onset, and high burden of risk factors. | 2020-11-18 |
| 33205991 | The primary outcome was SARS-CoV-2 infection in the mask wearer at 1 month by antibody testing, polymerase chain reaction (PCR), or hospital diagnosis. | 2020-11-18 |
| 33206004 | If NG-Test® is used in seroprevalence surveys, we recommend that its diagnostic performance be taken into consideration to obtain a reliable estimation. | 2020-11-18 |
| 33206635 | This global sequencing effort is inherently decentralized and must rely on data collected by many labs using a wide variety of molecular and bioinformatic techniques. | 2020-11-18 |
| 33206653 | Of these, 165 had a PCR-based diagnosis and 36 had a retrospective diagnosis by antibody testing. […] Signs of pneumonia occurred in 39 of the 165 individuals with a PCR-based diagnosis of COVID-19 (23.6%). | 2020-11-18 |
| 33206690 | The early detection and differential diagnosis of respiratory infections increase the chances for successful control of COVID-19 disease. […] The nucleic acid RT-PCR test is regarded as the current standard for molecular diagnosis. […] In addition, recent evidence indicated that the initial missed diagnosis of asymptomatic patients with SARS-CoV-2 and discharged patients with “re-examination positive” might be due to low viral load, and the ability of rapid mutation of SARS-CoV-2 also increases the rate of false-negative results. | 2020-11-18 |
| 33206816 | It is important that healthcare professionals draw attention to this fact, since these changes can help make diagnosis and initiate early treatment. | 2020-11-18 |
| 33206833 | Our study provides an initial examination of characteristics associated with receiving a doctor’s diagnosis of COVID-19 among a nationally representative sample of Brazilians aged 50 and over. […] Results show that about 2.4% (n = 70) of the sample reported being told by a doctor they had COVID-19, however, only about half of these individuals (n = 37) reported receiving a diagnostic confirmation from viral testing (RT-PCR). […] Demographic factors (aged 50-60 years), socioeconomic factors (lower household income), health-related factors (obesity, three or more chronic conditions), and geography (living in the Northern region of the country) were positively associated with reporting a COVID-19 diagnosis. | 2020-11-18 |
| 33206842 | Detection of viral particles in feces seems to be more persistent in children and can be used as a tool for diagnosis and control of the quarantine period. | 2020-11-18 |
| 33206843 | Case 1, female, 10-month-old child, pre-existing chronic disease, hospitalized since birth, mechanical ventilation dependency via tracheotomy, progressed with hypoxemia, requiring oxygen therapy, and increased ventilator parameters, and a diagnosis of COVID-19 was confirmed. […] Case 2, male, nine years old, previous psychiatric disease and obesity, showed worsening of the sensory state, requiring intensive care and invasive mechanical ventilation, with the diagnosis of SARS-Cov-2 infection. | 2020-11-18 |
| 33206973 | We assessed the expression of CD169, a type I interferon-inducible receptor, on monocytes (mCD169) in 53 adult patients admitted to the hospital during the COVID-19 outbreak for a suspicion of SARS-CoV-2 infection. mCD169 was strongly overexpressed in 30 out of 32 (93.7%) confirmed COVID-19 cases, compared to three out of 21 (14.3%) patients in whom the diagnosis of COVID-19 was finally ruled out. mCD169 was associated with the plasma interferon alpha level and thrombocytopenia. mCD169 testing may be helpful for the rapid triage of suspected COVID-19 patients during an outbreak. | 2020-11-18 |
| 33207153 | Diagnosis of the initial 3 COVID-19 cases led to contact tracing, symptom screening, and testing of 495 persons and limited quarantine of affected institutes or departments. | 2020-11-18 |
| 33207548 | In the present study, we evaluated, by means of a standardized diagnostic method, the SARS-CoV-2 infection prevalence amongst patients affected by severe acute respiratory syndrome (SARI) in an academic hospital located in Central Italy during the period of 1 November 2019-1 March 2020. | 2020-11-19 |
| 33207742 | The present study aimed at identifying psychological and psychosocial variables that might predict weight gain during the COVID-19 lockdown in patients affected by overweight/obesity with and without a psychiatric diagnosis. […] An online survey was administered between 25 April and 10 May 2020, to investigate participants’ changes in dietary habits during the lockdown period. 110 participants were recruited and allocated to two groups, 63 patients had no psychiatric diagnosis; there were 47 patients with psychiatric diagnosis. […] Weight gain during lockdown was reported by 31 of the participants affected by overweight/obesity without a psychiatric diagnosis and by 31 patients with a psychiatric diagnosis. […] Weight gain predictors were stress and low depression for patients without a psychiatric diagnosis and binge eating behaviors for patients with a psychiatric diagnosis. […] Of patients without a psychiatric diagnosis, 60% reported much more frequent night eating episodes. […] The risk of night eating syndrome in persons affected by overweight/obesity with no psychiatric diagnosis should be further investigated to inform the development of tailored medical, psychological, and psychosocial interventions. | 2020-11-19 |
| 33208083 | A lot of diagnostic and therapeutic modalities have been proposed for COVID-19 management. | 2020-11-19 |
| 33208116 | No clinical scoring system has yet been established to estimate the likelihood of coronavirus disease (COVID-19) and determine the suitability of diagnostic testing in suspected COVID-19 patients. […] The COVID-19 Clinical Risk Score may enable the risk classification of patients suspected of having COVID-19 and can help in decision-making in clinical practice, including appropriateness of diagnostic testing. | 2020-11-19 |
| 33208117 | Apps and websites were evaluated in terms of existing evidence for effectiveness, use of behaviour change techniques (BCTs), and quality. | 2020-11-19 |
| 33208288 | There was profound effect of the lockdown on referrals to OMFS from the ED, in number and type of diagnosis. | 2020-11-19 |
| 33208314 | Actors and elements across these five settings define what a good diagnostic is, yet their needs might conflict or change and they are difficult to access. | 2020-11-19 |
| 33208399 | The aim of this study is to evaluate the diagnostic accuracy of POCUS in patients with suspected pulmonary manifestations of COVID-19 in the ED. […] This prospective diagnostic accuracy study was conducted at the ED of our non-academic level 1 trauma centre (Isala, Zwolle, the Netherlands). […] Outcome of POCUS was compared with PCR or CT scan outcome to determine diagnostic accuracy. […] Diagnostic accuracy measures were calculated using 2×2 contingency tables. 100 patients were eligible to participate in this study, data of 93 patients were analysed. 27 (29%) patients were found positive for COVID-19 by PCR or CT. | 2020-11-19 |
| 33208457 | Globally, the COVID-19 pandemic has had extreme consequences for the healthcare system and has led to calls for diagnostic tools to monitor and understand the transmission, pathogenesis, and epidemiology, as well as to evaluate future vaccination strategies. | 2020-11-19 |
| 33208558 | The diagnosis of SARS-CoV-2 infection was confirmed by real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat and/or nasopharyngeal swabs. | 2020-11-19 |
| 33208927 | Data from patients with coronavirus disease 2019 (COVID-19) are essential for guiding clinical decision making, for furthering the understanding of this viral disease, and for diagnostic modelling. […] The open database may have further uses in the diagnosis and management of patients with COVID-19. | 2020-11-19 |
| 33209119 | The objective of this update is to provide answers to the questions pertaining to the diagnostic testing of SARS-CoV-2 for both cancer patients and healthcare professionals caring for cancer patients, as well as the recommended protective measures and practices that may be instituted in healthcare facilities. | 2020-11-19 |
| 33209166 | Chest imaging is a useful adjunct for diagnosis, documenting the extent of disease as well as observation of changes and is thus, strongly recommended in suspected COVID-19 cases, for initial evaluation, differential diagnoses and follow-up. | 2020-11-19 |
| 33209174 | Real-time reverse transcriptase polymerase chain reaction (RT-PCR) tests for SARS-CoV-2 nucleic acid were performed using nasopharyngeal swabs (novel coronavirus PCR fluorescence diagnostic kit, BioGerm medical biotechnology) at the Nigeria Centre for Disease Control (NCDC) in Abuja, Nigeria. | 2020-11-19 |
| 33209367 | With the assistance of AI, CT could evaluate the clinical severity of COVID-19 pneumonia more precisely and help the early diagnosis and surveillance of the patients. | 2020-11-19 |
| 33209535 | Real-time reverse transcription-polymerase chain reaction (rRT-PCR) from a viral swab is diagnostic. […] We present the case of a patient who had a COVID-19 diagnostic swab through his tracheostomy, when unfortunately the swab broke, resulting in a bronchial foreign body. | 2020-11-19 |
| 33209547 | Average serum lactate was 4.33 mmol/L at time of diagnosis. | 2020-11-19 |
| 33209627 | Among other disciplines, also cytopathology is key in diagnosis and treatment management of these patients. […] Indeed, cytopathology specimens are often the only source of available tissue material for morphological diagnosis and molecular purposes in order to guarantee an adequate treatment decision making, since surgical resection specimens are not available when lung cancer is diagnosed at advanced disease stages. | 2020-11-19 |
| 33209762 | Before you proceed for an aerosol-generating procedure like RCT, and crown preparations, diagnosis, and screening of COVID-19 is very important, as failure may end up infecting yourself and would become a source of infection to your patient community. | 2020-11-19 |
| 33209764 | However, their significance in diagnosis, as well as predicting prognosis, remains to be established. […] There appears to be no specific manifestation at present, but a high index of suspicion can help in the diagnosis of patients presenting with cutaneous lesions as the first manifestation. | 2020-11-19 |
| 33210052 | Thus, particle swarm optimization techniques demonstrate very high potential for the prediction of Mortality caused due to COVID-19. | 2020-11-19 |
| 33210075 | PCR and chest CT were performed in all hospitalized patients to confirm the diagnosis (100% positive PCR, 71% positive CT). | 2020-11-19 |
| 33210121 | There was no significant increase or decrease in the risk of pneumothorax in patients treated with invasive mechanical ventilation after the diagnosis of coronavirus disease 2019-related pneumonia/acute respiratory distress syndrome. | 2020-11-19 |
| 33210274 | The primary outcome was COVID-19-related death and the secondary outcome was the need for invasive mechanical ventilation. 4,248,253 obese individuals aged 15-75 years were included and followed for a mean observation time of 5.43 ± 2.93 years. 8286 individuals with a previous diagnosis of obesity were admitted for COVID-19 between January 1 and May 15, 2020. | 2020-11-19 |
| 33210442 | Lung and breast cancer are most prominently discussed, and the most concerns were expressed regarding delayed diagnosis, cancellations, missed treatments, and weakened immunity. | 2020-11-19 |
| 33210494 | This group of diseases is prone to be misdiagnosed or missed diagnosis, resulting in serious tissue and visual damage. […] Etiological diagnosis is a powerful auxiliary mean to diagnose the ocular diseases associated with human adenovirus, herpes simplex virus 1 and varicella-zoster virus, and it provides the leading diagnosis evidence of infections with herpes simplex virus 2, Epstein-Barr virus, cytomegalovirus, HHV-6/7, HHV-8, HTLV-1 and SARS-CoV-2. […] Virus isolation, immunoassay and genetic diagnosis are usually used for etiologic diagnosis. […] For genetic diagnosis, the PCR technique is the most important approach because of its advantages of rapid detection, convenient operation, high sensitivity and high specificity. | 2020-11-19 |
| 33210528 | A distinct pathway has been set up to keep patients of uncertain COVID-19 diagnosis separated from all other patients. | 2020-11-19 |
| 33210776 | Diagnosis was established after a median of 15 days under mechanical ventilation. | 2020-11-19 |
| 33211319 | Specific diagnostic tests to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and resulting COVID-19 disease are not always available and take time to obtain results. […] To assess the diagnostic accuracy of routine laboratory testing as a triage test to determine if a person has COVID-19. […] We included both case-control designs and consecutive series of patients that assessed the diagnostic accuracy of routine laboratory testing as a triage test to determine if a person has COVID-19. | 2020-11-19 |
| 33211392 | This review provides a comprehensive overview for the use of saliva as a specimen for the detection of SARS-CoV-2, the methods for the salivary diagnostics utilized till very recently, and the arisen considerations for the diagnosis of COVID-19 disease. […] The major advantage of using saliva as a specimen for the detection of SARS-CoV-2 is that saliva collection is a non-invasive method which produces no discomfort to the patient and permits the patients to utilize home self-sampling techniques in order to protect health providers from the exposure to the pathogen. | 2020-11-19 |
| 33211423 | Chronicle of a crisis management at the Clinical Microbiology Laboratory of CHU Liège The SARS-CoV-2 outbreak in December 2019 in China and its expansion across the world and Europe have requested the participation of clinical laboratories as major players in the diagnosis of COVID-19, to perform PCR tests mainly on nasopharyngeal swabs. | 2020-11-19 |
| 33211427 | In the course of the pandemic induced by the appearance of a new coronavirus (SARS-CoV-2; COVID-19) causing acute respiratory distress syndrome (ARDS), we had to rethink the diagnostic approach for patients suffering from respiratory symptoms. […] Indeed, although the use of RT-PCR remains the keystone of the diagnosis, the delay in diagnosis as well as the overload of the microbiological platforms have led us to make almost systematic the use of thoracic imaging for taking in charge of patients. […] In this context, thoracic imaging has shown a major interest in diagnostic aid in order to better guide the management of patients admitted to hospital. | 2020-11-19 |
| 33211429 | Moreover, there is an overlap between signs and symptoms of pulmonary embolism and COVID-19, which brings a challenge for the diagnosis and could potentially be fatal. | 2020-11-19 |
| 33211432 | In this review the principal cutaneous manifestations associated with COVID-19 are described as well as their eventual value in terms of diagnostic aid or as prognostic factor. | 2020-11-19 |
| 33211534 | Incorporating the added value of social benefits into cost-effectiveness analyses does not mean that manufacturers should capture the entire societal benefit of a diagnostic, vaccine, or therapy. | 2020-11-19 |
| 33211737 | Computed tomography (CT) of the chest-primarily usually conducted as low-dose, non-contrast enhanced CT-plays an important role in the diagnosis and follow-up of COVID-19 pneumonia. | 2020-11-19 |
| 33212828 | Twenty-four patients received chemotherapy a month prior to COVID-19 diagnosis. […] Three patients required oxygen at the time of diagnosis. | 2020-11-20 |
| 33213035 | A cohort of 93 patients, with a diagnosis of COVID-19 is analyzed. | 2020-11-20 |
| 33213264 | The number of online consultations has increased with diagnosis of upper respiratory tract infection, psychological conditions, COVID-19-related investigations and interventions. | 2020-11-20 |
| 33213324 | Finally, we discuss important aspects of the development of diagnostic tools and therapeutic countermeasures that have potential to help in controlling the COVID-19 pandemic. | 2020-11-20 |
| 33213364 | A positive PCR test for COVID-19, and a CT scan of the chest showing bilateral consolidations with ground-glass opacities confirmed the diagnosis. | 2020-11-20 |
| 33213370 | At the first phase, the cutoff value of positive likelihood of 18 provided 100% specificity and 100% positive predictive value for the diagnosis of sepsis. | 2020-11-20 |
| 33213393 | Repeated nucleic acid tests for COVID-19 are necessary to achieve accurate case diagnosis. […] The characteristic rashes of dermatomyositis require careful observation and can often provide diagnostic clues. | 2020-11-20 |
| 33213435 | Deep learning techniques are particularly suited to complex datasets with non-linear solutions, which make them appropriate for use in conditions with a paucity of prior knowledge. | 2020-11-20 |
| 33213870 | Radiology departments play a fundamental role in the management of COVID-19, both in the diagnosis of the disease and in the posterior management of patients. | 2020-11-20 |
| 33214202 | Diagnosis of SDB and initiation of treatment pose some specific problems to be addressed to preserve safety of the patients and health personnel. | 2020-11-20 |
| 33214412 | Our clinical results support the findings that suggested a susceptibility of the ocular surface to the virus and it underlines the importance of the ocular surface assessment in post-COVID-19 patients for a correct diagnosis and therapy. | 2020-11-20 |
| 33214969 | A diagnosis of SARS-Cov-2-associated peripheral neuropathy was considered. | 2020-11-20 |
| 33215150 | In all, 15 patients (9%) had a perioperative diagnosis of COVID-19, 14 of whom had fragility fractures; six died within 30 days of their procedure (40%, 30-day mortality). | 2020-11-20 |
| 33215176 | Conclusion and relevance: Our two cases highlight the importance of making the correct diagnosis and timely decision-making to consider if delivery for maternal compromise is warranted. | 2020-11-20 |
| 33215463 | Finally, this paper illustrates different types of diabetes management techniques, such as blood glucose management, self-management, mental health management, and therapeutic management. | 2020-11-20 |
| 33215473 | Reverse transcription-polymerase chain reaction (RT-PCR) is known as one of the primary diagnostic tools. […] Moreover, most countries are suffering from a lack of testing kits because of limitations on budget and techniques. […] Thus, this standard method is not suitable to meet the requirements of fast detection and tracking during the COVID-19 pandemic, which motived to employ deep learning (DL)/convolutional neural networks (CNNs) technology with X-ray and CT scans for efficient analysis and diagnostic. […] This study provides insight about the literature that discussed the deep learning technology and its various techniques that are recently developed to combat the dissemination of COVID-19 disease. | 2020-11-20 |
| 33216256 | Consumer-grade wearable sensors have drastically expanded RPM capabilities from just the sickest cardiac patients to the entire population aiding in early diagnosis and real-time disease management. | 2020-11-20 |
| 33216448 | We propose practical guidance for the diagnosis and management of COVID-19 coagulopathy in persons with haemophilia. | 2020-11-20 |
| 33216524 | This method may prove effective for the accurate diagnosis of MDR bacterial pathogens, thus preventing severe infection by ensuring appropriate antibiotic treatment. | 2020-11-20 |
| 33216658 | Augmented reality programs using wearable assistive devices are a home-based therapy, with the potential for reinforcing physical therapy techniques; this is especially meaningful during the COVID-19 pandemic when access to both medical and rehabilitative care has been curtailed. | 2020-11-20 |
| 33216694 | Serologic tests for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) provide information on past infection and immune response. | 2020-11-20 |
| 33216726 | Advanced surveillance techniques are essential to inform public health decision making and to identify where and when corrective action is required to prevent outbreaks. […] Standard surveillance techniques such as daily and cumulative infections and deaths are helpful but only provide a static view of what has already occurred in the pandemic and are less helpful in prevention. | 2020-11-20 |
| 33216772 | We have assessed the performance of serum apolipoprotein-A1, the main transporter of HDL-cholesterol, to identify the early spread of coronavirus disease 2019 (Covid-19) in the general population and its diagnostic performance for the Covid-19. […] Apolipoprotein-A1 at the 1.25 g/L cutoff had a sensitivity of 90.6% (95%CI84.2-95.1) and a specificity of 96.1% (95.7-96.6%) for the diagnosis of Covid-19. | 2020-11-20 |
| 33217046 | There is an urgent need for a reliable, inexpensive diagnostic test, an effective treatment and an approved and readily available vaccine. | 2020-11-20 |
| 33217055 | We conducted a prospective observational study tracing and analyzing the screening uptake and the trend of compliance to diagnostic colonoscopy in fecal immunochemical test-positive subjects in the National Taiwan University Hospital screening hub since the outbreak of COVID-19 and compared it with that of the corresponding periods in the past 3 years. […] In order to resume the practice in COVID-19 era, screening organizers should consider various approaches to secure timely diagnosis of colorectal cancer. | 2020-11-20 |
| 33217121 | However, as diagnosis is critical for any therapy, it is of the utmost importance to report the existence of system changes and their exact location to prevent them from spreading. […] Especially in the space of diagnostic self-reporting systems, the recent SARS-CoV-2 (COVID-19) pandemic indicates an urgent need for such concepts that may be able to detect the presence of viruses or bacteria on and within materials in a self-reporting fashion. | 2020-11-20 |
| 33217262 | This report highlights some of the initial difficulties and delay in diagnosis encountered earlier in the pandemic with limited testing supplies and processing labs; however, prompt ED recognition and treatment still led to a favorable outcome. | 2020-11-20 |
| 33217420 | In subgroup meta-analyses, the incidence of VTE was higher when assessed according to screening (33.1% vs 9.8% by clinical diagnosis), among patients in the ICU (27.9% vs 7.1% in the ward), in prospective studies (25.5% vs 12.4% in retrospective studies), and with the inclusion of catheter-associated thrombosis/isolated distal DVTs and isolated subsegmental PEs. | 2020-11-20 |
| 33217674 | The pooled prevalence, sensitivity, specificity, and diagnostic odds ratio of imaging findings were calculated. […] The diagnostic accuracy of radiographic findings could not be assessed due to small number of studies. […] GGO on CT has the highest diagnostic performance for COVID-19 pneumonia, followed by GGO plus consolidation and consolidation only. […] However, the moderate to low sensitivity and specificity suggest that CT should not be used as the primary tool for diagnosis. | 2020-11-20 |
| 33217784 | We included critically ill patients, performed GM-EIA and GM-Lateral Flow Assay (GM-LFA) in TA and followed them until development of COVID-19-associated pulmonary aspergillosis (CAPA) or alternate diagnosis. […] The diagnostic performance of GM in tracheal aspirates improved after using a cut-off of 2 OD. | 2020-11-20 |
| 33217886 | We retrospectively investigated the demographic information, recent exposure history, clinical symptoms or signs, comorbidity, chest computed tomographic (CT) scan or X-ray results, laboratory test results, diagnostic classification, treatment, length of hospitalization, complications, and outcomes.Of the 93 patients, 54 were male and 39 female. | 2020-11-21 |
| 33218097 | In this paper, an overview of the progress made in the development of nanobiosensors for the detection of human coronaviruses (SARS-CoV, SARS-CoV-2, and Middle East respiratory syndrome coronavirus (MERS-CoV) is presented, along with specific techniques for modifying the surface of nanobiosensors. | 2020-11-21 |
| 33218270 | Further high-quality RCTs with adequate sample sizes are required to compare the different techniques of ONB as well as comparing this method with general anesthesia with complete neuromuscular blockade. | 2020-11-21 |
| 33218366 | Primary outcomes will be all-cause mortality; a diagnosis of COVID-19; and serious adverse events. | 2020-11-21 |
| 33218670 | Demographic variables, comorbidities, reasons for consultation and diagnosis, treatment and readmission were included. […] The diagnosis distribution was similar between both periods; however, perianal abscesses doubled their rate in 2020, 22.4% versus 11.3% (p=0.045). | 2020-11-21 |
| 33218850 | 37.5% of patients with a new diagnosis of cancer in 2018 had an IFR ≥5%. | 2020-11-21 |
| 33218946 | The world is facing an emerging viral disease for which no specific treatment is available, and many aspects of the clinical behavior of the disease are still unknown, which makes the diagnosis and management a big challenge. | 2020-11-21 |
| 33218990 | This study assessed the diagnostic performance of the new COVID19SEROSpeed IgM/IgG rapid test (BioSpeedia, a spinoff of the Pasteur Institute of Paris) for the detection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in comparison to other commercial antibody assays through a large cross-European investigation. […] Moreover, by detecting the presence of antibodies prior to 11 days PSO in 78.2% of the patients, the BioS test increased the efficiency of the diagnosis of SARS-CoV-2 infection in the early stages of the disease. | 2020-11-21 |
| 33219225 | The COVID-19 pandemic has highlighted that new diagnostic technologies are essential for controlling disease transmission. […] Here, we develop SHINE (Streamlined Highlighting of Infections to Navigate Epidemics), a sensitive and specific diagnostic tool that can detect SARS-CoV-2 RNA from unextracted samples. […] SHINE has the potential to be used outside of hospitals and clinical laboratories, greatly enhancing diagnostic capabilities. | 2020-11-21 |
| 33219228 | Here we report the development of a molecular diagnostic test for SARS-CoV-2 based on an enhanced recombinase polymerase amplification (eRPA) reaction. eRPA has a detection limit on patient samples down to 5 viral copies, requires minimal instrumentation, and is highly scalable and inexpensive. eRPA does not cross-react with other common coronaviruses, does not require RNA purification, and takes ~45 min from sample collection to results. eRPA represents a first step toward at-home SARS-CoV-2 detection and can be adapted to future viruses within days of genomic sequence availability. | 2020-11-21 |
| 33219294 | Patients were classified based on whether they received ACE-I or ARB before COVID-19 diagnosis. | 2020-11-21 |
| 33219449 | The current global fight against coronavirus disease (COVID-19) to flatten the transmission curve is put forth by the World Health Organization (WHO) as there is no immediate diagnosis or cure for COVID-19 so far. […] In order to stop the spread, researchers worldwide are working around the clock aiming to develop reliable tools for early diagnosis of severe acute respiratory syndrome (SARS-CoV-2) understanding the infection path and mechanisms. […] Currently, nucleic acid-based molecular diagnosis (real-time reverse transcription polymerase chain reaction (RT-PCR) test) is considered the gold standard for early diagnosis of SARS-CoV-2. […] Antibody-based serology detection is ineffective for the purpose of early diagnosis, but a potential tool for serosurveys, providing people with immune certificates for clearance from COVID-19 infection. […] Methods used for diagnosis of the discovered human coronavirus (SARS, MERS, COVID-19) including nucleic acid detection, gene sequencing, antibody detection, antigen detection, and clinical diagnosis are presented. […] Their merits, demerits and prospects are discussed which can help the researchers to develop new generation of advanced diagnostic tools for accurate and effective control of human coronavirus transmission in the communities and hospitals. | 2020-11-21 |
| 33220127 | Variability can be mostly explained by the differing sources of cases (hospital vs. community-based), the accuracy of the diagnostic approach and the interpretation of the patients’ complaints. | 2020-11-21 |
| 33220171 | In an observational study utilizing data from a Massachusetts group medical practice, we identified 1449 patients with a COVID-19 diagnosis. | 2020-11-21 |
| 33220439 | Various pool sizes (five, 10 and 15 samples) were evaluated prior to RNA extraction followed by standard RT-qPCR for the diagnosis of COVID-19. | 2020-11-21 |
| 33220447 | Imaging plays a central role in the diagnosis and management of COVID-19 pneumonia, with chest X-ray examinations and computed tomography (CT) being undoubtedly the modalities most widely used, allowing for a fast and sensitive detection of infiltration patterns associated with COVID-19 pneumonia. | 2020-11-21 |
| 33220456 | Salivary tests for the new coronavirus (SARS-CoV-2) diagnosis have been suggested as alternative methods for the nasopharyngeal and oropharyngeal tests. | 2020-11-21 |
| 33220632 | Analyses comprised calculation of percentages of participants meeting a provisional PTSD and mental health diagnosis (flourishing, moderate, languishing); a binary logistic regression with demographics, work-related features, and positive mental health as predictors, and provisional PTSD diagnosis as outcome. […] Out of 653 participants, 39.8% received a provisional PTSD diagnosis; 33.4% reported flourishing, 57.7% moderate, and 8.9% languishing mental health. […] Regression analysis highlighted that women vs. men, nurses vs. technical/rehabilitation HW, frontline vs. second-line workers and languishing vs. moderately mentally healthy HW were more likely to receive a provisional PTSD diagnosis, whereas flourishing participants were more likely not to receive it. | 2020-11-21 |
| 33220640 | In this prospective study, 2 new 3D printed nasopharyngeal swab designs were evaluated against the standard, flocked nasopharyngeal swab for the diagnosis of COVID-19. […] Seventy adult patients (37 COVID-positive and 33 COVID-negative) underwent consecutive diagnostic reverse transcription polymerase chain reaction testing, with a flocked swab followed by one or two 3D printed swabs. | 2020-11-21 |
| 33220699 | Timely diagnosis of the coronavirus disease 2019 (COVID-19) improves the survival of the patients and also prevents the transmission of the infection. […] In this study, we reviewed the applicable and available methods for the diagnosis of COVID-19. […] For the review, we systematically searched Web of Science, PubMed, and Iranian articles that were published about COVID-19 diagnostic methods with a combination of the key terms: laboratory, radiological, tests, coronavirus. […] Although the current gold standard diagnostic test for this virus is real-time reverse-transcriptase polymerase chain reaction (RT-PCR), the occasional false-negative and the low sensitivity of the test should not be underestimated. […] A chest computed tomography (CT) scan is another diagnostic test for COVID-19, with higher sensitivity but low specificity. […] A combination of sensitive RT-PCR with a chest CT scan together with the clinical features are highly recommended for the proper diagnosis. […] Since early and accurate diagnosis of the viral disease could improve the survival rate of the patients, and halt the transmission chain, it is not surprising that tremendous attempts should be made to reduce the limitations of the tests leading to the false-negative results and to find a rapid test for the diagnosis of COVID-19. | 2020-11-22 |
| 33220700 | Meanwhile, further studies are needed to investigate the utility of cardiac biomarkers as diagnostic and prognostic tools for long-term cardiac complications of this infection. | 2020-11-22 |
| 33220960 | After diagnosis of the first symptomatic patient, surgery was suspended. […] Twenty patients were found to be positive for SARS-CoV-2 sometime after cardiac surgery (mean age 69 ± 10.4 years; median European System for Cardiac Operative Risk Evaluation II score 3 [interquartile range, 5.1]); the median time from surgery to diagnosis was 15 days (interquartile range, 11). […] The systemic inflammatory state that follows extracorporeal circulation may mask the typical COVID-19 laboratory findings, making the diagnosis more difficult. | 2020-11-22 |
| 33220973 | Early presentation and prompt diagnosis of acute appendicitis are necessary to prevent progression of disease leading to complicated appendicitis. | 2020-11-22 |
| 33221039 | The results reviewed here highlight the importance of considering and further investigating the impact of the current pandemic on the diagnosis and treatment of panic disorder (alone or comorbid with the COVID-19). | 2020-11-22 |
| 33221115 | However, the published literature has not established whether PCT changes could aid in the diagnosis of infectious complication during the COVID-19 pandemic. | 2020-11-22 |
| 33221936 | The most urgent interventions needed in the present climate include epidemiological measures to reduce the spread of infection, efficient treatment of patients with severe illness to reduce mortality rates, as well as development of diagnostic tests. | 2020-11-22 |
| 33222008 | Data on demographics, diagnosis, operation, and treatment recommendation/outcome were collected and analysed. | 2020-11-22 |
| 33222462 | The enrolled patients were those with confirmed diagnosis of severe or critical COVID-19 pneumonia, who received HDIVC within 24 hours after disease aggravation. | 2020-11-23 |
| 33222992 | Significant disruptions occurred to breast imaging, including deferred screening mammography, triaging diagnostic breast imaging, and changes in breast cancer care algorithms. | 2020-11-23 |
| 33223148 | Feedback was obtained from interviewees and the NCJDRSU team on their experiences. 50 cases were diagnosed with sporadic CJD; 5 received an alternative diagnosis, and the remaining 4 remained unresolved, with further investigations underway. | 2020-11-23 |
| 33223221 | The inclusion criteria were strictly founded on a final histopathological diagnosis of a malignant gynecologic tumor. | 2020-11-23 |
| 33223368 | We retrospectively abstracted cT1b-T2bN0M0 RCC patients from the National Cancer Database, stratifying them by clinical stage and time from diagnosis to surgery. […] Patients were grouped by having surgery within 1 month, 1-3 months, or >3 months after diagnosis. […] Delaying surgery >3 months after diagnosis did not confer pT3a upstaging risk among cT1b (OR = 0.90; 95% CI: 0.77-1.05, P = 0.170), cT2a (OR = 0.90; 95% CI: 0.69-1.19, P = 0.454), or cT2b (OR = 0.96; 95% CI: 0.62-1.51, P = 0.873). | 2020-11-23 |
| 33223409 | Studies that investigated adults (aged ≥18 years) with a diagnosis of any cancer, irrespective of treatment type, cancer stage or primary/secondary nature of disease were included. | 2020-11-23 |
| 33223418 | The proposed model is a non-contact process of determining whether a subject is infected or not and is achieved by using chest radiographs; one of the most widely used imaging technique for clinical diagnosis due to fast imaging and low cost. | 2020-11-23 |
| 33223552 | Data collected included patient demographics, duration of symptoms, method of diagnosis, treatment, severity of disease, length of stay and complications. | 2020-11-23 |
| 33223609 | In so doing, the diagnosis of a politically induced, objectively measurable deceleration is pivotal. […] In a second step, the social theoretical conclusions from this diagnosis are drawn in contrast to system theory on the one hand, and neomarxist approaches on the other. | 2020-11-23 |
| 33223625 | We have identified 10 criteria on which the best HCW disposal techniques to be selected based on extant literature review. […] The results help the municipal authorities to establish a methodical approach to choose the best HCW disposal techniques. | 2020-11-23 |
| 33223629 | There are a large number of complex factors driving the spread of pandemics, and, as a result, multiple modeling techniques play an increasingly important role in shaping public policy and decision-making. | 2020-11-23 |
| 33223662 | In many patients, neurological manifestations preceded other systemic features or the diagnosis of COVID-19. […] Sick patients with COVID-19 will require ICU care and many patients may present first to the neurocritical care ICU and receive a diagnosis of COVID-19 later. | 2020-11-23 |
| 33223748 | With these objectives, some modifications in the operating theater including surgical techniques for minimal access, laparoscopy, and robotic surgery are proposed in this review article. | 2020-11-23 |
| 33223833 | Diagnosis and monitoring of disease progression are done by regular screening of laboratory parameters, including D-dimer and fibrinogen. […] Coagulopathy is a poor prognostic factor, and optimum strategies should be developed for early diagnosis, prevention, and prompt treatment of VTE in COVID-19 patients. | 2020-11-23 |
| 33224275 | Cases with clinical-radiological diagnosis of COVID-19 (COVID-like ILIs), were also reported. | 2020-11-23 |
| 33224307 | The early diagnosis of infected patients is needed to discontinue this outbreak. […] The diagnosis of coronavirus infection from radiography images is the fastest method. […] In this paper, two different ensemble deep transfer learning models have been designed for COVID-19 diagnosis utilizing the chest X-rays. […] Experimental results reveal that the proposed framework outperforms the existing techniques in terms of sensitivity, specificity, and accuracy. | 2020-11-23 |
| 33224361 | As this is a novel virus, its diagnosis is crucial to clinical treatment and management. […] To date, real-time reverse transcription-polymerase chain reaction (RT-PCR) has been recognized as the diagnostic criterion for COVID-19. […] In this review, we aim to discuss the diagnosis and main CT features of patients with COVID-19 based on the results of the published literature, in order to enhance the understanding of COVID-19 and provide more detailed information regarding treatment. | 2020-11-23 |
| 33224384 | In this single-center, retrospective study, we evaluated patients admitted with ST-segment elevation myocardial infarction (STEMI) or non-ST-segment elevation myocardial infarction (NSTEMI) during early months of the COVID-19 pandemic (March 11, 2020 to April 20, 2020) compared to patients admitted with same diagnosis during the same period a year prior. | 2020-11-23 |
| 33224386 | This is a retrospective cohort study of patients with a diagnosis of COVID-19 admitted to a tertiary center between March 2020 and July 2020. | 2020-11-23 |
| 33224493 | We aim to highlight the importance of early diagnosis and management in such clinical scenarios to avoid fatal complications. | 2020-11-23 |
| 33224549 | Significant abdominal distention and subsequent diagnostic imaging showed pneumoperitoneum and a possible perforation of the stomach. | 2020-11-23 |
| 33224596 | Awareness of complications more likely to arise in specific ethnicities will allow a more timely diagnosis and preventive measures for patients at risk. | 2020-11-23 |
| 33224602 | As female patients usually experience longer delays before diagnosis and treatment, we assessed whether women were more affected by the dramatic drop in hospital admissions for ACS during the Covid-19 pandemic. […] There was a significant decrease driven by a similar reduction in ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI) diagnosis in both sexes compared to the control periods. […] A trend toward a greater reduction in admitted females was shown in the intra-year control period (46% admission reduction in females vs 37% in males, with females accounting for 26% of ACS, P=0.10) and a significant reduction when compared to the previous year control period (40% admission reduction in females vs 23% in males, with females accounting for 28% of ACS, P=0.03), mainly related to Unstable Angina diagnosis. | 2020-11-23 |
| 33224626 | Between January 1 and 31 August 2020, UpToDate® added more than 40 topic reviews on various aspects of COVID-19 diagnosis and management, and developed new methods for delivering COVID-19 content to our learners. | 2020-11-23 |
| 33224906 | Consensus on diagnosis, management, and prevention of pediatric COVID-19 were drawn up based on the analysis of such data plus insights gained from the past SARS and MERS coronavirus outbreaks. | 2020-11-23 |
| 33224961 | These clinical features combined with clinical symptoms of COVID-19 may aid in the timely diagnosis of patients with COVID-19. | 2020-11-23 |
| 33224993 | In this current review, we outline pathogenesis, diagnosis, treatment, ongoing clinical trials, prevention, and precautions. | 2020-11-23 |
| 33225111 | He was not tested for COVID-19 at the time of his respiratory complaints.The clinical examination and the ancillary tests confirmed the diagnosis of a left eye Central Retinal Vein Occlusion.During admission, a real-time reverse transcription-polymerase chain reaction (RT-PCR) for SARS-CoV-2 from a nasopharyngeal swab was performed and was found to be negative, however, an IgG/IgM Rapid Test (Inzek International Trading, the Netherlands) was performed and was found to be IgM negative and IgG Positive for SARS-CoV-2, confirming recovery from COVID-19. | 2020-11-23 |
| 33225216 | To meliorate this situation, we adopted the management concept of the system of Tiered Diagnosis and Treatment and developed an online tool for self-triage based on the mostly used multi-purpose smartphone app Wechat in China. | 2020-11-23 |
| 33225222 | Among the supportive diagnostic methods in 3 different geriatric age groups, PCR positivity has no effect on mortality, while the ground glass opacity on tomography is closely related to the need for intensive care and increased mortality. | 2020-11-23 |
| 33225318 | Rapid, robust virus-detection techniques with ultrahigh sensitivity and selectivity are required for the outbreak of the pandemic coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). […] Finally, we design a LC-based diagnostic kit and a smartphone-based application (app) to enable automatic detection of SARS-CoV-2 ssRNA, which could be used for reliable self-test of SARS-CoV-2 at home without the need for complex equipment or procedures. | 2020-11-23 |
| 33225319 | We have developed a globally applicable diagnostic COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. […] In addition, we have hosted our quarantine diagnosis results for the top 70 affected countries worldwide, on a public platform. | 2020-11-23 |
| 33225352 | With the COVID-19 pandemic, there have been supply challenges necessitating that laboratories must prepare their own viral transport medium (VTM), which provides stability for clinical specimens for diagnostic viral testing. | 2020-11-23 |
| 33225382 | Intensive care unit workers are at high risk of acquiring COVID-19 infection, especially when performing invasive techniques and certain procedures that generate aerosols (< 5 μm). | 2020-11-23 |
| 33225476 | CT provides rich diagnosis and severity information of COVID-19 in clinical practice. | 2020-11-23 |
| 33225565 | We believe that the structural and organizational changes adopted early on and the diagnosis algorithm played an important role in minimizing the spread of the disease. | 2020-11-23 |
| 33225728 | Two months prior to her diagnosis she completed a course of rituximab and chlorambucil chemotherapy for a relapse of diffuse large cell B-cell lymphoma (DLBCL). | 2020-11-23 |
| 33225911 | Hospital database of inpatients admitted to Loghman Hakim hospital between February 20th and May 11th, 2020 was reviewed and all patients with final diagnosis of COVID-19 infection were evaluated for their presenting symptoms. | 2020-11-23 |
| 33225958 | Moreover, owing to the high mutation rate of RNA viruses, periodic surveillance on emerging variants of key virus components is essential for evaluating the efficacy of antiviral drugs, diagnostic assays and vaccines. […] Our data provided a glimpse into the sequence diversity of a primary antiviral drug and diagnostic target. | 2020-11-23 |
| 33225959 | In addition, due to the limited availability of diagnostic tests in Italy during the pandemic period and the relative reliability of the test results, the diagnostic suspicion of CV19 infection in most of the children was difficult to confirm. […] In the absence of reliable, highly sensitive diagnostic tests or when nasal swab is unworkable or there are too many requests to be performed quickly due to the pandemic, LUS should be used in children with persistent cough for whom a CV19 is suspected because it can highlight undiagnosed interstitial lung lesions and reinforce the diagnostic suspicion of CV19 This approach can be very useful in outpatient settings and in areas with limited medical resources such as developing countries. | 2020-11-23 |
| 33226018 | PCD diagnosis is often missed or delayed due to challenges with different diagnostic modalities. […] Ciliary videomicroscopy, using Digital High-Speed Videomicroscopy (DHSV), one of the diagnostic tools for PCD, is considered the optimal method to perform ciliary functional analysis (CFA), comprising of ciliary beat frequency (CBF) and beat pattern (CBP) analysis. […] To continue providing a diagnostic service during this health crisis, the ciliary videomicroscopy protocol has been adapted to include adequate infection control measures. […] We also illustrate the importance of obtaining and processing optimal quality epithelial ciliated strips, as samples not meeting quality selection criteria do now allow for CFA, potentially decreasing the diagnostic reliability and the efficiency of this technique. | 2020-11-23 |
| 33226333 | The survey employed the Research Diagnostic Criteria for insomnia disorder to diagnose acute insomnia disorder. 573 respondents had no missing data pertaining to sleep, with a mean age of 43.4 + 12.5 years and 72% women. | 2020-11-23 |
| 33226415 | However, several other diagnosis groups were associated with a higher risk of positive test results: malignant disorders (SR, 1.54 [95% CI, 1.19-1.93]), cardiac disorders (SR, 1.18 [95% CI, 1.05-1.32]), endocrinologic disorders (SR, 1.52 [95% CI, 1.31-1.75]), gastrointestinal disorders (SR, 2.00 [95% CI, 1.04-1.38]), genetic disorders (SR, 1.19 [95% CI, 1.00-1.40]), hematologic disorders (SR, 1.26 [95% CI, 1.06-1.47]), musculoskeletal disorders (SR, 1.18 [95% CI, 1.07-1.30]), mental health disorders (SR, 1.20 [95% CI, 1.10-1.30]), and metabolic disorders (SR, 1.42 [95% CI, 1.24-1.61]). […] The number of patients with a diagnosis of Kawasaki disease in early 2020 was 40% lower (259 vs 433 and 430) than in 2018 or 2019. […] Kawasaki disease diagnosis is not an effective proxy for multisystem inflammatory syndrome of childhood. | 2020-11-23 |
| 33226473 | Considerable impact on people: “I take ages to eat a main course … This is embarrassing and I often leave food even though I am still hungry.” (no diagnosis, EAT-10 = 17). | 2020-11-23 |
| 33226521 | Although the reference diagnostic test is a real-time reverse transcription-polymerase chain reaction (RT-PCR), chest-computed tomography (CT) has been frequently used in diagnosis because of the low sensitivity rates of RT-PCR. […] We also discuss the features that may aid in the differential diagnosis, as the disease continues to spread and will be one of our main differential diagnoses some time more. | 2020-11-23 |
| 33226957 | Conventional diagnosis of COVID-19 with reverse transcription polymerase chain reaction (RT-PCR) testing (hereafter, PCR) is associated with prolonged time to diagnosis and significant costs to run the test. […] We sought to develop (ie, train and internally validate with cross-validation techniques) and externally validate a machine learning model to rule out COVID 19 using only routine blood tests among adults in emergency departments. | 2020-11-23 |
| 33227020 | A critical priority is, therefore, to quickly develop serological diagnostic capacity and identify individuals with past exposure to SARS-CoV-2. | 2020-11-23 |
| 33227028 | To evaluate the diagnostic performance of the initial chest CT to diagnose COVID-19 related pneumonia in a French population of patients with respiratory symptoms according to the time from the onset of country-wide confinement to better understand what could be the role of the chest CT in the different phases of the epidemic. […] Overall, CT revealed patterns suggestive of COVID-19 in 603 patients (57%), whereas an alternative diagnosis was found in 246 patients (23%). […] At the peak of the epidemic, chest CT had sufficiently high sensitivity and PPV to serve as a first-line positive diagnostic tool but at the end of the epidemic wave CT is more useful to exclude COVID-19 pneumonia. | 2020-11-23 |
| 33227045 | Psychiatry, more than any other field in medicine stands to benefit through tele-psychiatry as a physical examination may not be always necessary to arrive at a diagnosis. | 2020-11-23 |
| 33227297 | Direct infection of extrapulmonary tissues has been postulated, and using sensitive techniques, viral RNA has been detected in multiple organs in the body, including the kidney. | 2020-11-23 |
| 33227343 | Genomic surveillance of SARS-CoV-2 was implemented in March of 2020 at a major diagnostic hub in Bangkok, Thailand. | 2020-11-23 |
| 33227735 | The goal of this paper was to apply unsupervised machine learning techniques towards the discovery of latent COVID-19 clusters in patients with chronic lower respiratory diseases (CLRD). | 2020-11-23 |
| 33227752 | As preliminary results of this research, very influential features that emerged are the presence of cardiac and liver illnesses and the levels of some inflammatory parameters at the moment of diagnosis. | 2020-11-23 |
| 33227808 | This paper also introduces the corresponding changes in the diagnosis and treatment of urological diseases during the COVID-19 pandemic. | 2020-11-23 |
| 33227940 | This article shows how to use simulation techniques to prepare hospitals for a virus outbreak. | 2020-11-24 |
| 33228475 | The study explored significant insights for better diagnosis, and therapeutic options for COVID-19. | 2020-11-24 |
| 33229369 | The 3 techniques included PPE alone, a polycarbonate intubating box, or a coronavirus flexible enclosure, which consisted of a Mayo stand with plastic covering. […] Of the 3 techniques, the coronavirus flexible enclosure contained the fluorescent marker more effectively during endotracheal intubation than PPE alone or the intubating box based on exposure of the laryngoscopist and supporting RT. | 2020-11-24 |
| 33229732 | As circulating extracellular vesicles can be used as non-invasive liquid biopsies, their specific cargo-signatures (including deiminated proteins and microRNAs) may allow for disease “fingerprinting” and aid early central nervous system disease diagnosis, inform disease progression and response to therapy. | 2020-11-24 |
| 33229949 | Among them, monoclonal anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies have been isolated by multiple laboratories in record time facilitated by techniques that were first pioneered for HIV-1 antibody discovery. […] Research laboratories that successfully identified potent broadly neutralizing antibodies against HIV-1 have harnessed their antibody discovery techniques to isolate novel potent anti-SARS-CoV-2 antibodies, which have efficacy in animal models. | 2020-11-24 |
| 33229953 | The authors present a case of acute invasive fungal rhino-orbital mucormycosis in a patient with COVID-19 and discuss the prevalence, diagnosis, and treatment of fungal coinfections in COVID-19. | 2020-11-24 |
| 33229999 | Health system leaders seeking innovative approaches can have access to well-established tool kits, guiding models, and materials toward many organizational health literacy goals across treatment, diagnosis, prevention, education, research, and outreach. | 2020-11-24 |
| 33230033 | Tele-neuro-ophthalmology programs can be used for triage, diagnostic consultation, and long-term treatment monitoring. | 2020-11-24 |
| 33230395 | However, due to the inadequate number of Reverse Transcription Polymerase Chain Reaction (RT-PCR) tests, Chest computed tomography (CT) becomes a popular tool to assist the diagnosis of COVID-19. | 2020-11-24 |
| 33230398 | It is hence very important to design an automated and early diagnosis system which can provide fast decision and greatly reduce the diagnosis error. […] This paper proposes a DL assisted automated method using X-ray images for early diagnosis of COVID-19 infection. | 2020-11-24 |
| 33230485 | LP results impacted treatment decisions in 10 (37%) patients, either by change of antibiotics, influence in disposition decision, or by providing an alternative diagnosis. | 2020-11-24 |
| 33230500 | We evaluated a nationwide administrative database of all hospitalized patients with main diagnosis of acute ischemic stroke with/without diagnosis of Covid-19 who were hospitalized during the time period from January 16th to May 15th, 2020. […] We compared case numbers, treatment characteristics (intravenous thrombolysis, IVT; mechanical thrombectomy, MT; treated on an intensive care unit, stroke unit or regular ward) and in-hospital mortality of AIS with and without concurrent diagnosis of Covid-19. | 2020-11-24 |
| 33230503 | To investigate the diagnostic performance of an Artificial Intelligence (AI) system for detection of COVID-19 in chest radiographs (CXR), and compare results to those of physicians working alone, or with AI support. […] Fifty-four physicians blind to diagnosis, were invited to interpret images under identical conditions in a test set, and randomly assigned either to receive or not receive support from the AI system. […] Comparisons were then made between diagnostic performance of physicians working with and without AI support. […] When working with AI support, physicians increased their diagnostic sensitivity from 47% to 61% (p < 0.001), although specificity decreased from 79% to 75% (p = 0.007). […] Our results suggest interpreting chest radiographs (CXR) supported by AI, increases physician diagnostic sensitivity for COVID-19 detection. | 2020-11-24 |
| 33230505 | Inclusion criteria included age ≥18 years and being on regular follow up with the diagnosis of premature MI (documented MI before the age of 55 years) at least for one year. | 2020-11-24 |
| 33230510 | However, further clinical trials and larger cohort studies are essential to evaluate effective diagnostic and management options for this high-risk group. | 2020-11-24 |
| 33230627 | A range of molecular and immunoassay-based techniques ranging from central laboratory testing to point-of-care tests is urgently needed for the diagnosis and management of COVID-19 patients. | 2020-11-24 |
| 33230819 | We conclude that all seven commercially available RT-PCR kits included in this study can be used for routine molecular diagnosis of COVID-19. | 2020-11-24 |
| 33230987 | Preemptive testing increased the positive test rate (3.9% to 4.2%), an asymptomatic case at diagnosis (16.9% to 30.6%), and reduced the time from symptom onset to quarantine (4.0 to 3.0 days). | 2020-11-24 |
| 33230988 | While providing a comprehensive understanding of the scenarios most conducive to carrying out a survey, the role of ethical approval, survey validation and pilot testing, this brief delves deeper into the survey designs, methods of dissemination, the ways to secure and maintain data anonymity, the various analytical approaches, the reporting techniques and the process of choosing the appropriate journal. | 2020-11-24 |
| 33231148 | Information about techniques that are adjuvant to ventilatory support is superficial and require further investigation. | 2020-11-24 |
| 33231160 | Using Deep Learning models, the research aims at evaluating the effectiveness and accuracy of different convolutional neural networks models in the automatic diagnosis of COVID-19 from X-ray images as compared to diagnosis performed by experts in the medical community. | 2020-11-24 |
| 33231205 | Among the different procedures used by the ENT, acoustic analysis of voice has become widely used for correct diagnosis of dysphonia. | 2020-11-24 |
| 33231312 | Although RT-PCR-based nucleic acid detection has been primarily used in the diagnosis of COVID-19, it is time-consuming with limited application scenarios and must be operated by qualified personnel. | 2020-11-24 |
| 33231841 | Nasopharyngeal/oropharyngeal, oral cavity, saliva, rectal, urine, and blood samples are collected from patients who were hospitalized with diagnosis of COVID-19 on admission. | 2020-11-24 |
| 33232211 | Based on advances in techniques for vaccine design, inactivated, live-vectored, nucleic acid, and recombinant COVID-19 vaccines are being developed and tested for their efficacy. | 2020-11-24 |
| 33232368 | The DL algorithm demonstrated a satisfactory diagnostic performance comparable with that of formal radiology reports in the CR-based diagnosis of pneumonia in COVID-19 patients. | 2020-11-24 |
| 33232456 | On bivariate and multivariable analyses, a diagnosis of ulcerative colitis or IBD-unspecified was associated with a lower odds of stopping medication compared with Crohn’s disease [adjusted odds ratio (aOR) 0.6, 95% confidence interval (CI) 0.48, 0.75]. | 2020-11-24 |
| 33232587 | New-onset and current HF patients must understand their diagnosis and future prognosis and seek help and support using the appropriate platform when needed. | 2020-11-24 |
| 33232684 | Relative to those not receiving diabetes medications, residents taking metformin were at significantly reduced hazard of death [adjusted hazard ratio (HR) 0.48, 95% confidence interval (CI) 0.28, 0.84] over the subsequent 30 days from COVID-19 diagnosis. | 2020-11-24 |
| 33232817 | The field of stem cells and regenerative medicine has provided a paradigm shift in treating a disease with minimally invasive techniques that provides maximal clinical and functional outcome for patients. | 2020-11-24 |
| 33232832 | We proposed that a multidisciplinary expert panel can establish recommendations on ideal use of diagnostic tools, with a focus on RT-PCR and serological high-affinity antibodies (both IgM and IgG) tests for the Latin America region. […] A collaborative multidisciplinary panel of 5 recognized experts in Latin America (an infectious disease specialist, three pathologists, and an immunologist) was convened and supported by Roche Diagnostics to develop standard guidelines and an evidence-based document of best practices on the use of diagnostic tools for COVID-19. […] The authors reached consensus on the applicability of diagnostic tools to provide testing algorithms for the use of RT-PCR and serological high-affinity antibodies (both IgM and IgG) tests in three settings: 1) For asymptomatic subjects exposed to a SARS-CoV-2 infected person; 2) For epidemiological purposes and; 3) For symptomatic subjects. […] The serological high-affinity SARS-CoV-2 antibodies (both IgM and IgG) tests play a key role in COVID-19 diagnosis. | 2020-11-24 |
| 33233013 | Suspending the diagnosis and treatment of non-virus related diseases for longer periods of time is not a viable option since this would only exacerbate problems on the patient and national level. […] So far, telemedical applications have mainly focused on teleradiological diagnosis, follow-up and monitoring of psychiatric and internal diseases, as well as geriatric patient care. […] This feasibility study explores how video consultation can be designed and implemented in the context of history taking and physical examination in knee joint complaints. 21 patient actors (PA) with simulated complaints of the knee joint were examined individually for each diagnosis, first via video consultation and then directly by a specialist (SP). […] The physician documented the detected symptoms, the quality of implementation of the self-examination steps, and the derived diagnosis on an assessment form. | 2020-11-24 |
| 33233390 | The nursing students indicated that they improved their knowledge on GBV victim management (mainly their awareness of the problem, recognition of the role of nursing professionals, and performance of non-technical skills), although they also mentioned the need for continuous training (particularly in socio-emotional skills, interview techniques, a holistic nursing care approach, and not presupposing). | 2020-11-25 |
| 33233409 | Long diagnostic delays (LDDs) in patients with coronavirus disease 2019 (COVID-19) might decrease the effectiveness of patient isolation in reducing subsequent transmission. […] The mean diagnostic delay for 364 cases was 6.3 days. | 2020-11-25 |
| 33233425 | It also identified miRNAs that could be used in personalized diagnosis in COVID-19. | 2020-11-25 |
| 33233428 | Air-liquid interface (ALI) culture of nasal epithelial cells is a valuable tool in the diagnosis and research of primary ciliary dyskinesia (PCD). […] Ex vivo samples often display secondary dyskinesia from cell damage during sampling, infection or inflammation confounding PCD diagnostic results. […] We describe a revised ALI culture method adopted from April 2018 across three collaborating PCD diagnostic sites, including current University Hospital Southampton COVID-19 risk mitigation measures, and present results. […] Fifty-four of 83 (63.9%) ex vivo samples which were originally equivocal or insufficient provided diagnostic information following in vitro culture. […] In summary, our ALI culture protocol provides high ciliation rates across three centres, minimising patient recall for repeat brushing biopsies and improving diagnostic certainty. […] Cryostorage of surplus diagnostic samples was successful, facilitating PCD research. | 2020-11-25 |
| 33233531 | Together, key genes unraveled by genetic profiling may provide targets for precisely early risk diagnosis and prophylactic design to relieve severe COVID-19. | 2020-11-25 |
| 33234132 | In COVID-19 infection, KL-6 serum levels could therefore be of interest for diagnosis, prognosis and therapeutic response evaluation. | 2020-11-25 |
| 33234158 | Patients who meet the following criteria will be invited to participate: Inclusion criteria: (1) Over 18 years of age who reside in the province of Corrientes at the time of diagnosis. […] (2) Confirmed diagnosis of COVID-19 by polymerase chain reaction (PCR) test for detection of SARS-CoV2 in the last 48 h. […] (5) That they sign the informed consent for participation in the study. (1) pregnant or breastfeeding women; (2) known allergy to ivermectin or some of the components of ivermectin tablets or placebo; (3) current use of home oxygen; (4) require hospitalization due to COVID-19 at the time of diagnosis or history of hospitalization for COVID-19; (5) presence of mal-absorptive syndrome; (6) presence of any other concomitant acute infectious disease; (7) known history of severe liver disease, for example liver cirrhosis; (8) need or use of antiviral drugs at the time of admission for another viral pathology other than COVID-19; (9) need or use of hydroxychloroquine or chloroquine; (10) use of ivermectin up to 7 days prior to randomization; (11) patients on dialysis or who have required it in the last 2 months or who plan to do it in the next 2 months; and (12) current participation or in the last 30 days in a research study that has included the administration of a drug (Table 1). […] Over 18 years of age who reside in the province of Corrientes at the time of diagnosis 1. […] Confirmed diagnosis of COVID-19 by polymerase chain reaction test for detection of SARS-CoV2 in the last 48 h 2. […] That require hospitalization due to COVID-19 at the time of diagnosis or history of hospitalization for COVID-19 5. | 2020-11-25 |
| 33234296 | Therefore diagnostic testing is central to contain the global pandemic. […] Up to now real-time reverse transcriptase polymerase chain reaction (RT-PCR)-based molecular assays for detecting SARSCoV-2 in respiratory specimens is the current reference standard for COVID-19 diagnosis. […] In particular, it allows reaching the area with the highest diagnostic sensitivity. | 2020-11-25 |
| 33234416 | We have read the article by Yang et al, entitled “The diagnostic and predictive role of NLR, d-NLR and PLR in COVID-19 patients” with great interest. | 2020-11-25 |
| 33234651 | The measurement of IgM and IgG antibodies will be performed once per week for 6 consecutive weeks and then at 6, 12, 18, 24 and 36 months after the diagnosis. | 2020-11-25 |
| 33234660 | Of 14 150 patients included in CHESS until 13 May 2020, 401 lacked a confirmed diagnosis of COVID-19 and 7666 lacked a recorded date of symptom onset. | 2020-11-25 |
| 33234678 | Some of the catalysing enzymes of such reactions have demonstrated interactions with existing drugs, which can be used for experimental testing of the presented predictions using gene knockouts and RNA interference techniques. | 2020-11-25 |
| 33235080 | The time from a positive diagnosis to a negative result of 2 consecutive nucleic acid tests (not on the same day), cure rate. | 2020-11-25 |
| 33235559 | Main themes which emerged from the qualitative responses were social stigma and rejection, humiliating behaviour of others, breach of confidentiality, loss of trust/ respect, and impact of COVID-19 diagnosis on their business. | 2020-11-25 |
| 33235605 | Teledentistry is a subspecialty of telemedicine that helps in the provision of educational activities, advice, and diagnosis about treatment over a distance with the help of technology like video conferencing. | 2020-11-25 |
| 33235651 | The diagnosis of tuberculosis in the current pandemic of COVID-19 required a high degree of suspicion to rule out the SARS-CoV-2 infection along with the infection of Mycobacterium tuberculosis. | 2020-11-25 |
| 33235668 | These patients present predominantly with respiratory complaints; however, in this article, we describe a case that was detected incidentally during workup of another suspecting diagnosis. | 2020-11-25 |
| 33235672 | A total of 176 patients with confirmed COVID-19 diagnosis were included. | 2020-11-25 |
| 33235717 | The data included patient demographic parameters like age, gender and site of injury, mechanism of injury, diagnosis and procedure performed and carrying out of COVID-19 Polymerase Chain Reaction (PCR) test in the COVID-era. | 2020-11-25 |
| 33235826 | A check of arterial blood gas revealed normal partial pressure of oxygen and follow-up tests confirmed a methemoglobinemia diagnosis. | 2020-11-25 |
| 33235828 | The present study is about the detailed analysis of the pandemic Corona Virus 2019 which has rocked the entire world with a maximum impact with its structure, its appearance and nomenclature, Clinical presentation and transmission, diagnostic technique. | 2020-11-25 |
| 33235831 | Consistency among clinical symptoms, laboratory results and autopsy findings can be a quality measure in the diagnosis of coronavirus disease 2019 (COVID-19). | 2020-11-25 |
| 33235889 | Nasopharyngeal swabs are critical to the diagnosis of respiratory infections including coronavirus disease 2019, but collection techniques vary. […] We compared 2 recommended nasopharyngeal swab collection techniques in adult volunteers and found that swab rotation following nasopharyngeal contact did not recover additional nucleic acid (as measured by human DNA/RNA copy number). | 2020-11-25 |
| 33235892 | Patients with COVID-19 were identified using the relevant diagnostic code. […] Of the 1048 patients with CVD, 864 (82.4%) received at least 1 antihypertensive medication before the diagnosis of COVID-19, including 359 (41.6%) who received ACEIs/ARBs and 505 (58.4%) who received drugs other than ACEIs/ARBs. | 2020-11-25 |
| 33235985 | An Israeli national taskforce performed a multi-center clinical and analytical validation of seven serology assays to determine their utility and limitations for SARS-CoV-2 diagnosis. | 2020-11-25 |
| 33236131 | Additionally, several efficient diagnostic tools are being actively developed, and novel drugs and vaccines are being evaluated for their efficacy as therapeutic agents against COVID‑19, or in the prevention of infection. | 2020-11-25 |
| 33236268 | The worldwide urge for new diagnostic tools to control the pandemic has led to a quick incorporation in clinical practice of the recently developed serological assays. […] However, as only few comparative studies have been published, there is a lack of data about the diagnostic accuracy of currently available assays. […] We evaluated the diagnostic accuracy to detect Ig G, Ig M+A, and/or IgA anti SARS-CoV-2 of 10 different assays: lateral flow card immunoassays, 4 enzyme-linked immunosorbent assay (ELISA), and 3 chemiluminescent particle immunoassays (CMIA). […] Due to a better specificity, overall diagnostic accuracy of the assays evaluated was higher in case of positive result. […] Highest diagnostic accuracy was obtained with ELISA and CMIAs, but they last much longer. | 2020-11-25 |
| 33236269 | Due to global shortages of flocked nasopharyngeal swabs and appropriate viral transport media during the COVID-19 pandemic, alternate diagnostic specimens for SARS-CoV-2 detection are sought. | 2020-11-25 |
| 33236270 | Our study shows excellent performance of CMIA compared to immunochromatographic test and confirms its potential use in the diagnosis of the new SARS-CoV-2. | 2020-11-25 |
| 33236424 | In the last few years, we have witnessed an important development in the medical field of both Mobile Health, such as the use of mobile communication devices, and other telemedicine tools in general, in order to support the surveillance of diseases from the moment of the first diagnosis to the therapeutic follow-up. | 2020-11-25 |
| 33236431 | Some of these diseases are not only considered risk factors for severe reactions but also have symptoms such as cough and sneezing that are in differential diagnosis with COVID-19. | 2020-11-25 |
| 33236439 | We provided an overview of all the various cutaneous manifestations of COVID-19 described in the literature today, to improve our knowledge and lead a more prompt and accurate diagnosis, especially in asymptomatic or paucisymptomatic cases. | 2020-11-25 |
| 33237122 | In view of this scenario, the aim of this study was to present saliva as an alternative for seeking diagnostic and prognostic markers of COVID-19 in children, including adequate sample collection techniques for different age groups. | 2020-11-25 |
| 33237666 | Data were collected prospectively on predetermined data collection forms, including consultation duration, diagnosis, management plan, and issues that arose. | 2020-11-25 |
| 33237851 | This research sheds additional light on the importance of providing patients with viable safe alternatives to obtain diagnostic testing, guidance, and consults. | 2020-11-25 |
| 33237918 | This study will aid further research into the application of thermal infrared imaging as a screening or bedside diagnostic tool in clinical practice. | 2020-11-25 |
| 33238140 | The recurrence of infectious processes, associated with the severity of the condition and/or unusual profile of the infectious agent, always related to the age range of symptom onset, are the most important findings for suspected diagnosis. […] Considering this scenario, immunity disorders should be part of the investigation carried out by the general pediatrician, whether they are the innate errors of immunity (primary immunodeficiencies) or secondary immunodeficiencies, so that the diagnosis is attained as early as possible and therapeutic measures are implemented, reducing the morbidity and mortality of these patients. | 2020-11-25 |
| 33238933 | Admitted to the psychiatry ward in a state of mutism, he was discharged after 15 days with a diagnosis of “Major depressive disorder, single severe episode with no psychotic behavior”. | 2020-11-26 |
| 33239006 | Deep-learning artificial intelligent (AI) methods have the potential to help improve diagnostic efficiency and accuracy for reading portable CXRs. […] Deep-learning methods have the potential to improve diagnostic efficiency and accuracy for portable CXRs. | 2020-11-26 |
| 33239100 | Hospitalized with confirmed COVID-19 infection by real-time PCR or another validated method OR hospitalized with a non-COVID-19 diagnosis and quarantined at time of inclusion. […] A documented clinically relevant history of diabetes or newly discovered during hospitalization as defined by The World Health Organizations diagnostic criteria for diabetes. | 2020-11-26 |
| 33239366 | The significance of our study is that, using extensive SARS-CoV-2 genome analysis techniques, we identified potential interacting human host microRNA targets that share similarity with those of influenza A virus H1N1. | 2020-11-26 |
| 33239378 | RNA remnants purified from diagnostic nasopharyngeal specimens were used as the templates for RT-PCR-specific detection of SG E gene RNA. […] We assessed the samples of 60 RT-PCR-positive cases with prolonged viral SARS-CoV-2 shedding (24 to 101 days) since the first diagnostic RT-PCR. […] In a percentage of persistent SARS-CoV-2 PCR-positive cases, the presence of actively replicating virus may be inferred, far beyond diagnosis. | 2020-11-26 |
| 33239382 | Highly accurate testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at the point of care (POC) is an unmet diagnostic need in emergency care and time-sensitive outpatient care settings. | 2020-11-26 |
| 33239884 | The most popular initial diagnostic tools used for treatment initiation were arterial blood gas (48%) and clinical presentation (37.5%), while the national COVID-19 guidelines were the most used (61.2%). | 2020-11-26 |
| 33240557 | For those who accessed for orthopedic reasons, the analyzed variables included the date of ED admission, age, gender, after visit discharge or hospitalization, place where the injury occurred, traumatic mechanism, diagnosis, relationship with sport activity, and time from injury/symptoms debut to ED access. | 2020-11-26 |
| 33240788 | Its diagnosis depend on clinical symptoms, laboratory tests, and the typical CT chest scan findings. | 2020-11-26 |
| 33240881 | A SARS-CoV-2 diagnosis is conducted using quantitative reverse-transcription PCR and computed tomography (CT) imaging. […] This review includes the emergence of SARS-CoV-2 pneumonia as a way to recognize and eliminate any barriers that affect rapid patient care and public health management against the SARS-CoV-2 epidemic based on the natural history of the disease, its transmission, pathogenesis, immune response, epidemiology, diagnosis, clinical presentation, possible treatment, drug and vaccine development, prevention, and future perspective. | 2020-11-26 |
| 33241007 | To evaluate the role of high-resolution computed tomography (HRCT) in the diagnosis of 2019 novel coronavirus (2019-nCoV) pneumonia and to provide experience in the early detection and diagnosis of 2019-nCoV pneumonia. […] Moreover, the diagnostic accuracy of HRCT features combined with epidemiological history was not significantly different from the detection of viral nucleic acid (all P >0.05). […] The HRCT features of 2019-nCoV pneumonia are characteristic to a certain degree, which when combined with epidemiological history yield high clinical value in the early detection and diagnosis of 2019-nCoV pneumonia. | 2020-11-26 |
| 33241257 | Our Antenatal Diagnostic Centre (ADC) in KKH developed new strategies to adapt to the pandemic when the national Disease Outbreak Response System Condition (DORSCON) was raised from yellow to orange on 7 February 2020. | 2020-11-26 |
| 33241508 | Moreover, we noticed that treatment plans for thyroid cancer are considerably changing in the direction of more teleconsultations and less diagnostic and therapeutical procedures. | 2020-11-26 |
| 33241838 | LNPs are composed of ionizable cationic lipids, phosphatidylcholine, cholesterol, and polyethylene glycol (PEG)-lipids, and are produced using rapid-mixing techniques. | 2020-11-26 |
| 33242148 | The identification of all clinical manifestations of COVID-19 is essential for an early diagnosis and the adoption of preventive measures. | 2020-11-26 |
| 33242342 | The respiratory illness caused by SARS-CoV-2 infection continues to present diagnostic challenges. […] Early research showed thoracic (chest) imaging to be sensitive but not specific in the diagnosis of coronavirus disease 2019 (COVID-19). […] To evaluate the diagnostic accuracy of thoracic imaging (computed tomography (CT), X-ray and ultrasound) in people with suspected COVID-19. […] We included 34 studies: 30 were cross-sectional studies with 8491 participants suspected of COVID-19, of which 4575 (54%) had a final diagnosis of COVID-19; four were case-control studies with 848 cases and controls in total, of which 464 (55%) had a final diagnosis of COVID-19. […] Our findings indicate that chest CT is sensitive and moderately specific for the diagnosis of COVID-19 in suspected patients, meaning that CT may have limited capability in differentiating SARS-CoV-2 infection from other causes of respiratory illness. […] Because of limited data, accuracy estimates of chest X-ray and ultrasound of the lungs for the diagnosis of suspected COVID-19 cases should be carefully interpreted. […] Future diagnostic accuracy studies should pre-define positive imaging findings, include direct comparisons of the various modalities of interest on the same participant population, and implement improved reporting practices. […] Planned updates of this review will aim to: increase precision around the accuracy estimates for chest CT (ideally with low risk of bias studies); obtain further data to inform accuracy of chest X-rays and ultrasound; and obtain data to further fulfil secondary objectives (e.g. ‘threshold’ effects, comparing accuracy estimates across different imaging modalities) to inform the utility of imaging along different diagnostic pathways. | 2020-11-26 |
| 33242703 | Comparing patients hospitalised from February to May 2020 with those of the corresponding period in 2019 we observed a significantly increased number of TTS diagnosis in 2020 (11 patients vs 3 in 2019), especially during the first period of lockdown. | 2020-11-26 |
| 33242704 | The number of cases per capita in their state of residence, age, or proximity to someone with a COVID-19 diagnosis were not found to meaningfully predict perceived risk. | 2020-11-26 |
| 33242762 | We collected 166,005 English tweets posted between January 23 and June 22, 2020 and employed machine learning/natural language processing techniques to filter for relevant tweets, classify them by the type of effect they claimed, and identify topics of discussion. | 2020-11-26 |
| 33242917 | Therefore, its early detection is critical in prevention, diagnostic, and management efforts of COVID-19 patients. | 2020-11-26 |
| 33242972 | We observed a positive predictive value of 50% and a false positive rate of 50% in pregnant women, involving a significantly lower diagnostic performance than reported in non-pregnant patients. | 2020-11-27 |
| 33243126 | Difficulties in the diagnosis and access to ART and treatment nonadherence which may be encountered more frequently due to many factors may threaten both the health of people living with HIV and public health. | 2020-11-27 |
| 33243457 | Little is known about the effects of the coronavirus disease-2019 (COVID-19) pandemic on the diagnosis of anxiety disorder. […] Therefore, the goal of this study was to compare the number of adults with a diagnosis of anxiety disorder and the number of adults newly diagnosed with anxiety disorder in Germany between January-June 2019 and January-June 2020, and to identify potential differences in terms of sociodemographic characteristics, prescriptions and comorbidities between these patients. | 2020-11-27 |
| 33243677 | This preferentially affected certain journals and articles addressing specific topics, reflecting the intense public interest in the diagnosis and treatment of Covid-19. | 2020-11-27 |
| 33243801 | The 236 respondents reported illness compatible with COVID-19 and there was an increase in illness reporting during March 2020 Diagnostic swabs were not routinely performed. | 2020-11-27 |
| 33243940 | A number of studies have used modeling techniques and developed dynamic models to estimate the epidemiological parameters, explore and project the trends of the COVID-19, and assess the effects of intervention or control measures. | 2020-11-27 |
| 33244076 | This article addresses an optimisation problem of distributing rapid diagnostic kits among patients when the demands far surpass the supplies. […] Although the problem must be generalised before the actual deployment of the suggested strategy, the preliminary result is promising in its ability to address the shortage of diagnostic capacity currently observed worldwide because of the ongoing coronavirus disease pandemic. | 2020-11-27 |
| 33244256 | This was a retrospective study of adult patients admitted to a central London teaching hospital with a diagnosis of COVID-19 from 23rd March to 7th April 2020 identified from the hospital electronic database. | 2020-11-27 |
| 33244341 | With higher burden of malaria in Nigeria and other sub-Saharan African countries coupled with fragile healthcare system and delivery, these may pose a threat in the diagnosis and management of COVID-19 patients co-infected with malaria. | 2020-11-27 |
| 33244374 | The data provides valuable information for the discovery of prognosis biomarkers to diagnosis more severe disease in the early stages of COVID-19. | 2020-11-27 |
| 33244377 | Diagnosis, treatment, and isolation of children are the most effective ways to control the expansion of the COVID-19 pandemic. | 2020-11-27 |
| 33244380 | Introducing possible diagnostic and therapeutic biomarker candidates via the identification of chief dysregulated proteins in COVID-19 patients is the aim of this study. […] The introduced central proteins of the S-COVID-19 interaction network, particularly APOA1, can be considered as diagnostic and therapeutic targets related to the coronavirus disease after being approved with complementary studies. | 2020-11-27 |
| 33244462 | The reports of asymptomatic carriers changed the scenario of symptom based-diagnosis in COVID-19 and intensified the need for proper diagnosis of the majority of the population to combat the rapid transmission of virus. […] The diagnosis of positive cases is necessary to ensure prompt care to affected people and also to curb further spread of infection in the population. […] Collecting samples at the right time and from the exact anatomical site is crucial for proper molecular diagnosis. […] After the complete genome sequence was available, China formulated RT-PCR as a primary diagnostic procedure for detecting SARS-CoV-2. […] Many in-house and commercial diagnostic kits have been developed or are under development that have a potential to lower the burden of diagnosis on the primary diagnostic techniques like RT-PCR. […] Serological based diagnosis is another broad category of testing that can detect different serum antibodies like IgG, IgM, and IgA in an infected patient. […] PCR-based diagnostic procedures that are commonly used for pathogen detection need sophisticated machines and assistance of a technical expert. […] Despite their reliable accuracy, they are not cost-effective tests, which a common man can afford, so it becomes imperative to look for other diagnostic approaches, which could be cost effective, rapid, and sensitive with consistent accuracy. […] To make such diagnostics available to the common man, many techniques can be exploited among, which are Point of Care (POC), also known as bed side testing, which is developing as a portable and promising tool in pathogen diagnosis. […] Other lateral flow assay (LFA)-based techniques like SHERLOCK, CRISPR-Cas12a (AIOD-CRISPR), and FNCAS9 editor-limited uniform detection assay (FELUDA), etc. have shown promising results in rapid detection of pathogens. […] Diagnosis holds a critical importance in the pandemic situation when there is no potential drug for the pathogen available in the market. […] This review sums up the different diagnostic approaches designed or proposed to combat the crisis of widespread diagnosis due to the sudden outbreak of a novel pathogen, SARS-CoV-2 in 2019. | 2020-11-27 |
| 33244510 | Data collected included demographics (patient age, body mass index, sex), comorbidities, and blood test values along with COVID-19 diagnosis (based on positive microbiological sample and clinical and radiographic findings) and operative characteristics (time to operation, length of stay, American Society of Anesthesiologists [ASA] classification, Nottingham Hip Fracture Score). | 2020-11-27 |
| 33244523 | However, these symptoms are neither specific nor diagnostic for COVID-19. […] Since COVID-19 emerged and spread worldwide, many clinicians are focused on diagnosis and treatment of this novel viral infection. | 2020-11-27 |
| 33244570 | D-dimer is routinely measured to exclude the diagnosis of venous thromboembolism and is its main biomarker. […] In the absence of clinical improvement following treatment of other conditions in frail older patients, D-dimer testing could be indicated with pursuit of specific diagnostic evaluation for venous thromboembolism when significantly elevated. | 2020-11-27 |
| 33244678 | Situational analyses identifying extent and reasons for service disruptions and estimates of impacts using modelling techniques will guide prioritization of services. | 2020-11-27 |
| 33244690 | We conduct a series of diagnostic tests that prove the robustness of our estimates. | 2020-11-27 |
| 33245029 | Despite its rarity, in the differential diagnosis of acute abdomen, parenchymal renal rupture should always be considered in patients with abdominal pain and an anamnesis or history of urinary stones, pointing out the need of early diagnosis also in benign urological conditions. | 2020-11-27 |
| 33245241 | Although chest CT has been widely used in patients with COVID-19, its role for early diagnosis of COVID-19 is unclear. […] We report the diagnostic performance of chest CT using structured reporting in a routine clinical setting during the early phase of the epidemic in Germany. […] Structured reporting of chest CT with a five-grade scale provided accurate diagnosis of COVID-19. […] Chest CT with structured reporting may be a provisional diagnostic alternative to RT-PCR testing for early diagnosis of COVID-19, especially when RT-PCR results are delayed or test capacities are limited. | 2020-11-27 |
| 33245685 | The SARS-CoV-2 virus transmission chain is interrupted when screening and diagnosis can be performed on a large scale by identifying asymptomatic or moderately symptomatic patients. […] Diagnosis of COVID-19 with reverse transcription polymerase chain reaction (RT-PCR) has been limited due to inadequate access to complex, expensive equipment and reagents, which has impeded efforts to reduce the spread of virus transmission. […] Recently, the development of several diagnostic platforms based on the CRISPR-Cas system has reduced the dependence on RT-PCR. […] The first CRISPR-based diagnostic test for SARS-CoV-2 was recently approved by the U.S. […] The HUDSON-SHERLOCK and STOPCovid biosensing systems, as field-deployable and rapid diagnostic tests, can detect low-copy viruses in body fluids without nucleic acid extraction and with minimal equipment. […] In this review, we describe recent advances in CRISPR-based diagnostic platforms with an emphasis on their use in the rapid diagnosis and potential treatment of COVID-19. | 2020-11-27 |
| 33245734 | Mostly, lung ultrasound has been presented as having a role in diagnosis and monitoring, but airway examination and hemodynamic evaluation are of interest also. […] There are few extensive ultrasonographic studies in COVID-19 critically ill patients up to now, but techniques extrapolated from non-COVID studies seem reasonable even though comparative studies are not available yet. | 2020-11-27 |
| 33245895 | The diagnosis is a combined exercise of clinical and laboratory investigation similar to that performed by Bruton (1952). | 2020-11-27 |
| 33246271 | Our objectives were to develop a systematic approach for reporting likelihood of COVID-19 pneumonia on CXRs, to measure the interobserver variability of this approach and to evaluate the diagnostic performance of CXRs compared to real-time reverse transcription polymerase chain reaction (RT-PCR). […] For analysis of diagnostic accuracy, Characteristic and High Suspicion CXRs were considered positive and the remaining categories negative. | 2020-11-27 |
| 33246294 | Therefore, no findings alone, whether molecular, clinical, radiological or pathological axis are sufficient for an accurate diagnosis. […] However, their intersection and/or correlation are extremely critical for clinicians establish the diagnosis and new treatment perspectives. | 2020-11-27 |
| 33246431 | Since the first diagnosis on February 3rd, the epidemic has quickly evolved, with Belgium at the crossroads of Europe, being one of the hardest hit countries. | 2020-11-28 |
| 33246499 | Patients hospitalized with a confirmed diagnosis of COVID-19 are eligible when they are symptomatic (i.e. clinical or radiological signs) and have been diagnosed with COVID-19 in the 72 h before study inclusion through a PCR (nasal/nasopharyngeal swab or bronchoalveolar lavage) or a chest-CT scan showing features compatible with COVID-19 in the absence of an alternative diagnosis. | 2020-11-28 |
| 33246554 | They require a rapid diagnosis and an early treatment by a multidisciplinary team. […] As a result, we would like to describe two clinical cases a patient with diagnosis of COVID-19 pneumonia with good respiratory evolution that, after extubation suffered an acalculous cholecystitis and a patient with COVID-19 pneumonia that suffered an overinfection with necrotising pneumonia that presented with haemoptysis and was finally treated with arterial embolisation by the interventional radiologist’s team. | 2020-11-28 |
| 33246891 | Various teaching techniques can be employed through a virtual platform to introduce medical students to the specialty of urology and increase clinical knowledge surrounding common urologic conditions. […] As the longevity of the COVID-19 pandemic becomes increasingly apparent and virtual teaching is normalized, these techniques can have far-reaching utility within the traditional medical student surgical curriculum. | 2020-11-28 |
| 33247099 | Here we show detection of SARS-CoV-2 subgenomic RNAs in diagnostic samples up to 17 days after initial detection of infection and provide evidence for their nuclease resistance and protection by cellular membranes suggesting that detection of subgenomic RNAs in such samples may not be a suitable indicator of active coronavirus replication/infection. | 2020-11-28 |
| 33247152 | Our study provides important information for COVID-19 diagnosis, treatment, and vaccine development. | 2020-11-28 |
| 33247380 | One hundred ninety-one patients with a confirmed diagnosis of COVID-19 infection were randomized into two groups: group I (96) patients received both HCQ and zinc, and group II (95) received HCQ only. | 2020-11-28 |
| 33247586 | GeoSentinel has provided important contributions that have enhanced the ability to use destination-specific differences to guide diagnosis and treatment of returning travelers, migrants and refugees. | 2020-11-28 |
| 33247643 | Hence, routine screening of both symptomatic as well as asymptomatic hospital staff is essential for early diagnosis to prevent transmission of COVID 19 infection. | 2020-11-28 |
| 33247720 | Clinical informatics procedures need to be implemented nimbly, with governance measures in place to properly oversee and guide novel patient care pathways, diagnostic and treatment workflows, and provider education and communication. | 2020-11-28 |
| 33247907 | Historical inequities and social determinants of health are significant contributors to observed disparities and affect access to diagnostic testing for STI. […] Public health systems rely heavily on laboratory medicine professionals for diagnosis and reporting of STI. […] Therefore, it is imperative that clinicians and laboratory professionals be familiar with issues underlying disparities in STI incidence and barriers to reliable diagnostic testing. […] In this mini-review, we will summarize contributors to racial/ethnic disparity in STI, highlight current epidemiologic trends for gonorrhea, chlamydia, and syphilis, discuss policy issues that affect laboratory and public health funding, and identify specific analytic challenges for diagnostic laboratories. […] Laboratory professionals must be aware of these underlying issues and work to maximize efforts to ensure equitable access to diagnostic STI testing for all persons, particularly those most disproportionately burdened by STI. | 2020-11-28 |
| 33248470 | Shedding of infectious SARS-CoV-2 was observed up to 70 days, and of genomic and subgenomic RNA up to 105 days, after initial diagnosis. | 2020-11-29 |
| 33248536 | In this context, we discuss the use of doppler ultrasonography (DUS) in the screening and diagnosis of DVT in ambulatory and hospitalized patients with, or suspected of having, COVID-19, outside the intensive care unit (ICU). […] The use of 4-points compression DUS for DVT screen and diagnosis is the most appropriate method in this context. | 2020-11-29 |
| 33248689 | Open-access to advanced infrastructure for structural biology techniques at synchrotrons and high-end cryo-EM and NMR centres has brought these technologies centre-stage in drug discovery. | 2020-11-29 |
| 33248906 | We aim to review the current knowledge of how the disease threatens patients and DHCPs and how to determine which patients are likely to be SARS-CoV-2 infected; consider how the use of personal protective equipment and infection control measures based on current best practices and science can reduce the risk of disease transmission during radiologic procedures; and examine how intraoral radiography, with its potentially greater risk of spreading the disease, might be replaced by extraoral radiographic techniques for certain diagnostic tasks. | 2020-11-29 |
| 33248923 | New techniques for teaching and conducting exams have been introduced. | 2020-11-29 |
| 33249111 | All included subjects exhibited a reverse transcription-polymerase chain reaction-confirmed diagnosis of COVID-19. | 2020-11-29 |
| 33249696 | In the absence of an available affordable diagnostic test, detailed clinical history and physical examination are still fundamental to make a diagnosis. […] Physicians should consider alternate diagnosis that may mimic KD, particularly consider MIS-C during the present pandemic since an aggressive diagnostic and therapeutic approach is needed. | 2020-11-29 |
| 33249821 | The baby was discharged in good conditions. although gallbladder calcifications and echogenic bowel are highly suspicious of viral infection and were thought to be due to the vertical transmission of SARS-CoV-2, these findings were not corroborated by the results of our diagnostic tests; these sonographic findings might represent a false positive of fetal infection in mother affected by COVID-19 since vertical transmission appears to be rare. | 2020-11-30 |
| 33249904 | When adjusting for confounding variables (older age (p < 0.001), female sex (p = 0.004), hip fracture (p = 0.003), and increasing ASA grade (p < 0.001)) a diagnosis of COVID-19 was associated with an increased mortality risk (hazard ratio 1.89, 95% confidence interval (CI) 1.14 to 3.12; p = 0.014). | 2020-11-30 |
| 33249954 | All these circumstances have meant that Iran is restricted to provide the essential basic medical equipment for diagnosis, treatment and prevention of the COVID-19. | 2020-11-30 |
| 33249999 | Concomitant manifestations of COVID-19, such as severe pneumonia, which has similar clinical presentation with pulmonary embolism (PE), and barriers related to strict isolation protocols are the two main reasons why PE diagnosis might be more challenging in patients with COVID-19. | 2020-11-30 |
| 33250510 | Delays in cancer diagnosis and treatment due to the COVID-19 pandemic is a widespread source of concern, but the scale of the challenge for different tumour sites is not known. […] The number of referrals for suspected breast cancer was 28% lower (N = 231,765 versus N = 322,994), and the number of patients who received their first treatment for a breast cancer diagnosis was 16% lower (N = 19,965 versus N = 23,881). | 2020-11-30 |
| 33250561 | The control and prevention of COVID-19 in informal urban settlements starts with organizing community infrastructure for diagnosis and treatment and assuring that basic needs (food, water, sanitation, health care and public transport) are met during quarantine. | 2020-11-30 |
| 33250589 | In this situation, the recent research using radiology imaging (such as X-ray and CT scan) techniques can be proven helpful to detect COVID-19 as X-ray and CT scan images provide important information about the disease caused by COVID-19 virus. […] The latest data mining and machine learning techniques such as Convolutional Neural Network (CNN) can be applied along with X-ray and CT scan images of the lungs for the accurate and rapid detection of the disease, assisting in mitigating the problem of scarcity of testing kits. […] The performance of our proposed model was compared with ten existing techniques for COVID detection in terms of accuracy. | 2020-11-30 |
| 33250592 | Variations in the thoracic surgical techniques are necessary in order to protect the healthcare providers from COVID-19. | 2020-11-30 |
| 33250662 | The timely diagnosis of infected patients is a critical step to limit the spread of the COVID-19 epidemic. […] The efficiency and usefulness of the proposed COVID-CheXNet system are established along with the possibility of using it in real clinical centers for fast diagnosis and treatment supplement, with less than 2 s per image to get the prediction result. | 2020-11-30 |
| 33250751 | As a result, healthcare systems worldwide are not only experiencing diagnostic but also therapeutic and prognostic challenges with COVID-19-related complications. | 2020-11-30 |
| 33250932 | We explore COVID-19 treatment service options at the patient level (diagnosis, management, location and level of treatment) and measures to reduce nosocomial transmission (cohorting patients, protecting healthcare workers). | 2020-11-30 |
| 33251083 | The present investigation identified key genes and pathways that deepen our understanding of the molecular mechanisms of SARS-CoV-2 infection, and could be used for SARS-CoV-2 infection as diagnostic and therapeutic biomarkers. | 2020-11-30 |
| 33251090 | The serological tests did not contribute to a timely diagnosis of COVID-19 and generated confusion. […] We used oxygen therapy, broad spectrum antibiotics since the diagnosis of COVID-19. […] The early diagnosis and use of antibiotics at doses of sepsis, associated with corticosteroid pulses and respiratory physiotherapy improve COVID-19 pneumonia in postoperative lung surgery. | 2020-11-30 |
| 33251158 | For the diagnosis of COVID-19, the only reliable diagnostics is a qPCR assay. […] Among other diagnostic tools, the CRISPR-Cas system is being investigated for rapid and specific diagnosis of COVID-19. […] Apart from its diagnostic ability, CRISPR-Cas system is also being assessed for antiviral therapy development; however, till date, no CRISPR-based therapy has been approved for human use. […] This review is focused on describing potential use and challenges of CRISPR-Cas based approaches for the development of rapid and accurate diagnostic technique and/or a possible therapeutic alternative for combating COVID-19. | 2020-11-30 |
| 33251206 | To aid in the development of diagnostic kits for rapid and sensitive detection of the virus, we evaluated a combination of polymerase chain reaction (PCR) and isothermal nucleic acid amplification techniques. […] Here, we compared conventional PCR and loop-mediated isothermal amplification (LAMP) methods with hybrid techniques such as polymerase chain displacement reaction (PCDR) and a newly developed PCR-LAMP method. […] We found that the hybrid methods demonstrated higher sensitivity and assay reaction rates than those of the classic LAMP and PCR techniques and can be used to for SARS-CoV-2 detection. […] The proposed methods based on the modern hybrid amplification techniques markedly improve virus detection and, therefore, can be extremely useful in the development of new diagnostic kits. | 2020-11-30 |
| 33251373 | Articles in this collection adopt a diverse range of methods and techniques, and focus on the study of the narratives that fueled conspiracy theories, on the diffusion patterns of COVID-19 misinformation, on the global news sentiment, on hate speech and social bot interference, and on multimodal Chinese propaganda. […] In turn, these crucial endeavors might anticipate a growing trend of studies where diverse theories, models, and techniques will be combined to tackle the different aspects of online misinformation, manipulation, and abuse. | 2020-11-30 |
| 33251483 | Inclusion of a neurological assessment during diagnosis of COVID-19 might facilitate timely identification and effective management of the GBS symptoms and improve treatment outcome. | 2020-11-30 |
| 33252045 | To fight against the spread of the epidemic, generalized confinement a posteriori appears to have a disproportionate cost compared to its effectiveness, whereas the application of barrier gestures (breathing mask, hand hygiene, social distancing) should be promoted without any restriction, along with the diagnosis and temporary isolation of infected persons. | 2020-11-30 |
| 33252049 | Most patients were in the age group between 35-54 years of age and a large majority had mild symptoms at diagnosis. […] Interestingly, the prevalences of smoking and e-cigarette use were lower than in the Icelandic general population and they were not associated with symptom severity at diagnosis. | 2020-11-30 |
| 33252083 | It will no longer be possible to cram the humblest into cramped areas, but priority must be given to prevention (certainly with physical barriers, hydro-alcoholic gel, face masks), biological diagnosis, isolation, and also the care of any infected person. | 2020-11-30 |
| 33252101 | Understanding the epidemiology, clinical presentation, and management of MIS-C related to SARS-CoV-2 will help to streamline early diagnosis and treatment, particularly in pediatric patients with complex medical conditions. | 2020-11-30 |
| 33252292 | The occurrence of these psychological symptoms was significantly associated with the time spent on COVID-19 related news per day and partner with evidence of psychological disorder and, in females, with a diagnosis of poor ovarian reserve, diagnosis of endometriosis or uterine fibroids. | 2020-11-30 |
| 33252323 | In addition it is designed to inform a wider readership of the advances in the diagnosis and treatment of disease. […] These included a review of COVID-19 in this issue, 27 original articles, 6 Biomedical Science ‘In Brief’ and 4 case histories. 27 of the articles involved molecular techniques, with one of these comparing results with a mass spectrometry based method. | 2020-11-30 |
| 33252327 | Fever developed on February 22, and he was given a diagnosis SARS-CoV-2 infection on February 27. | 2020-11-30 |
| 33252531 | It has been reported worldwide that patients with a diagnosis of COVID-19 usually suffer a loss of smell and taste. […] The disease, smell, and taste functions of patients were evaluated with visual analog scores before diagnosis of COVID-19, during the disease, and fourth week after recovery. | 2020-11-30 |
| 33253226 | We also report a nsp3-C6310A substitution found in 47.3% of global B.6 sequences which was associated with reduced sensitivity using a commercial diagnostic real-time PCR assay. […] Shared genomic surveillance can be used to identify SARS-CoV-2 transmission chains to aid prevention and control, and to monitor diagnostic molecular assays. | 2020-11-30 |
| 33253398 | Students collaborated for a Complications Rounds activity (1-day) that promoted learning about procedural skills from a global perspective including safe techniques, monitoring, risks, and troubleshooting complications. | 2020-11-30 |
| 33253402 | It was divided into three phases and consisted of two activities for students to complete: (a) a webinar with previous autonomous student work, and (b) the design and creation of a clinical case by students with the nursing diagnosis “00030 impaired gas exchange” as the starting premise. | 2020-11-30 |
| 33253457 | Whilst the COVID-19 diagnostic test has a high false-negative rate, not everyone initially negative is re-tested. […] Characteristics, test results, and health outcomes for patients presenting for a COVID-19 diagnostic test were collected. | 2020-11-30 |
| 33253698 | The diagnosis of SARS-CoV-2 infection is currently based on the detection of viral RNA in nasopharyngeal swabs by means of molecular-based assays, such as real-time RT-PCR. | 2020-11-30 |
| 33253865 | Conditional formatting techniques, box plotting, time-series trends plotting methods, and spatial kriging interpolation mapping techniques were employed to show residential mobility trends. | 2020-11-30 |
| 33253926 | The IgM and IgA tests showed mostly insufficient performances with no added value for the early diagnostic on the cohort tested in this study. | 2020-11-30 |
| 33254065 | The purpose of this work was to analyze temporal variations in the diagnostic performance of chest CT for Covid-19 throughout the first wave, depending on disease prevalence variations between the ascending, peak and descending phases of the epidemic in North-Eastern France. […] CT diagnostic performance were calculated and variations between phases were tested for equivalence or difference using Bayesian methods. 2194 consecutive chest CT were analyzed. […] Overall CT diagnostic performance was Se = 84.2 [82.0 ; 86.3], Sp = 86.6 [84.5 ; 88.5], PPV = 86.1 [84.0 ; 88.1], NPV = 84.7 [82.6 ; 86.7] and accuracy = 85.4 [83.9 ; 86.8], with no significant differences between chest and non-chest radiologists. | 2020-11-30 |
| 33254202 | The aim of this article is to highlight the psychiatric impact of the COVID-19 pandemic on frontline HCWs, the need for screening and early diagnosis by general practitioners (GPs), and the appropriate psychosocial strategies and treatments to address this. | 2020-11-30 |
| 33254204 | The aim of this article is to provide guidance to GPs and healthcare staff working in Australia about the diagnosis and treatment of both newly developed and pre-existing PTSD in the COVID-19 context. | 2020-11-30 |
| 33254245 | It introduces a number of pitfalls in well-established clinical routines and poses unique challenges to diagnostic pathways. | 2020-11-30 |
| 33254367 | The diagnosis of CVST can be elusive, with wide-ranging and nonspecific presenting symptoms that can include headache or altered sensorium alone. […] To describe the presentation, barriers to diagnosis, treatment, and outcome of CVST in patients with COVID-19. | 2020-12-01 |
| 33254369 | The time taken from onset of COVID-19 symptoms to CVT diagnosis was a median of 7 days (IQR=6-14). | 2020-12-01 |
| 33254514 | A hypotheses pertaining to the presentation, diagnosis, management and possible prevention of SARS-CoV-2 is proposed. | 2020-12-01 |
| 33254534 | As of now, therapeutic strategies for the novel coronavirus (SARS-CoV-2) are limited and much focus has been placed on social distancing techniques to “flatten the curve”. | 2020-12-01 |
| 33254580 | Diagnostic biomarkers for periodontal disease have been researched extensively. | 2020-12-01 |
| 33254928 | Since no specific vaccines or drugs have been developed till date for the treatment of SARS-CoV-2 infection, early diagnosis is essential to further combat this pandemic. […] In this context, the reliable, rapid, and low-cost technique for SARS-CoV-2 diagnosis is the foremost priority. […] However, in a number of cases, false results have been noticed in COVID-19 diagnosis. […] To develop advanced techniques, researchers are continuously working and in the series of constant efforts, nanomaterials-enabled biosensing approaches can be a hope to offer novel techniques that may perhaps meet the current demand of fast and early diagnosis of COVID-19 cases. […] This paper provides an overview of the COVID-19 pandemic and nanomaterials-enabled biosensing approaches that have been recently reported for the diagnosis of SARS-CoV-2. […] Though limited studies on the development of nanomaterials enabled biosensing techniques for the diagnosis of SARS-CoV-2 have been reported, this review summarizes nanomaterials mediated improved biosensing strategies and the possible mechanisms that may be responsible for the diagnosis of the COVID-19 disease. […] It is reviewed that nanomaterials e.g. gold nanostructures, lanthanide-doped polysterene nanoparticles (NPs), graphene and iron oxide NPs can be potentially used to develop advanced techniques offered by colorimetric, amperometric, impedimetric, fluorescence, and optomagnetic based biosensing of SARS-CoV-2. […] This review may serve as a guide for the development of advanced techniques for nanomaterials enabled biosensing to fulfill the present demand of low-cost, rapid and early diagnosis of COVID-19 infection. | 2020-12-01 |
| 33256085 | Timely detection and diagnosis are essentially needed to guide outbreak measures and infection control. […] In this narrative review, the detection of coronavirus disease 2019 (COVID-19) technologies is summarized and discussed with a comparison between them from several aspects to arrive at an accurate decision on the feasibility of applying the best of these techniques in the biosensors that operate using laser detection technology. | 2020-12-01 |
| 33256816 | This may be explained by the varying techniques used by the two studies to determine severity. | 2020-12-01 |
| 33256878 | It was an ecological study utilising spatiotemporal analysis techniques that included all deaths confirmed by COVID-19 in Sergipe, from 2 April to 14 June 2020. […] Therefore, the use of spatial analysis techniques may contribute to surveillance and control of COVID-19 pandemic. | 2020-12-01 |
| 33256954 | Specific topics include preventing the spread of respiratory viruses, promoting immunization, and the diagnosis and treatment of suspected respiratory infection. | 2020-12-01 |
| 33256958 | Registration was performed on diagnostic status [confirmed (COVID-19+)/ruled out (COVID-19-)] and symptomatology (typical and atypical symptoms). | 2020-12-01 |
| 33256960 | We have developed a simple algorithm with a traffic light format for resident classification and sectorization within nursing homes, based on basic diagnostic tests, surveillance of symptoms onset, and close contact monitoring. | 2020-12-01 |
| 33257095 | This study aimed to assess the efficacy of a virtual information session hosted by a diagnostic radiology residency program at addressing applicant concerns about the 2020-2021 interview cycle and highlighting key aspects of the residency program. | 2020-12-01 |
| 33257144 | Outcomes were pediatric ED visit rates before and after the onset of pandemic, by age, disposition, and diagnosis. | 2020-12-01 |
| 33257293 | Patients with neurocognitive comorbidities were more likely to exhibit behavioral problems, especially externalizing problems compared with patients with a diagnosis of anxiety/depression. | 2020-12-01 |
| 33257396 | Recently, it has been recognised that COVID-19 may present in multi-systemic ways which can cause diagnostic uncertainty or error.We present a patient who attended hospital with features of Guillain-Barré syndrome (GBS) before developing clinical and radiological findings of COVID-19. […] While the authors recognise that neurological complications have been reported following COVID-19 infection, to their knowledge this report describes a unique presentation of GBS without preceding COVID-19 symptoms.Since these conditions may have considerable overlapping features including respiratory failure and (following prolonged critical care admission) profound weakness, it is possible that one diagnosis may be overlooked. | 2020-12-01 |
| 33257492 | Among a cohort of 308 patients with a diagnosis of COVID-19, 138 patients died while 170 patients recovered and were discharged from the hospital. | 2020-12-01 |
| 33257496 | We conducted a cohort study at Mass General Brigham in Boston, Massachusetts, of patients with RMD matched to up to five comparators by age, sex and COVID-19 diagnosis date (between 30 January 2020 and 16 July 2020) and followed until last encounter or 18 August 2020. | 2020-12-01 |
| 33257629 | We used snowball sampling techniques through an online structured questionnaire. | 2020-12-01 |
| 33257638 | Based on this, clinicians should have a low threshold to suspect a diagnosis of deep vein thrombosis/pulmonary embolism (DVT/PE), especially in the abdominal visceral region if a patient comes in several days after a COVID-19 diagnosis with abdominal pain. […] Whether or not empiric full dose anticoagulation is needed in patients without definite diagnosis of thromboembolism is still controversial. […] Further studies need to be done; meanwhile, we advocate the use of regular dose thromboprophylaxis in all hospitalized patients and therapeutic anticoagulation only when there is a confirmed diagnosis of thromboembolism. | 2020-12-01 |
| 33257910 | A total of 2113 members of two Facebook groups for coronavirus patients with persistent complaints in the Netherlands and Belgium, and from a panel of people who registered on a website of the Lung Foundation Netherlands, were assessed for demographics, pre-existing comorbidities, health status, date of symptoms onset, COVID-19 diagnosis, healthcare utilisation, and the presence of 29 symptoms at the time of the onset of symptoms (retrospectively) and at follow-up (mean±sd 79±17 days after symptoms onset). | 2020-12-01 |
| 33257914 | NoCoV-ARDS was identified by an ARDS diagnosis in the 5 years before the COVID-19 pandemic period. | 2020-12-01 |
| 33257915 | Images were analysed using internationally recognised techniques which included assessment of the pleura, number of B-lines, pathology in the PLAPS (posterolateral alveolar and/or pleural syndrome) point, bedside lung ultrasound in emergency profiles, and the lung ultrasound score. | 2020-12-01 |
| 33258019 | The most frequent diagnosis was rheumatoid arthritis with 17%, ANCA-associated vasculitis (AAV) with 14% and SLE with 12%. | 2020-12-01 |
| 33258165 | While the diagnostic value of anti-N antibodies is clear, their role in immunity is not. | 2020-12-01 |
| 33258333 | The KSTR members at 17 COVID-19 referral centers retrospectively collected imaging data and clinical information of consecutive patients with reverse transcription polymerase chain reaction-proven COVID-19 in respiratory specimens from February 2020 through May 2020 who underwent diagnostic chest computed tomography (CT) or radiograph in each participating hospital. | 2020-12-01 |
| 33258748 | Imaging of peripheral nerves in COVID-19 patients may help characterize nerve pathology, identify site and severity of nerve damage, and potentially elucidate mechanisms of injury thereby aiding the medical diagnosis and decisionmaking process. | 2020-12-01 |
| 33259358 | Treatment modalities range from resiliency techniques to trauma-focused cognitive behavioral therapy to pharmacotherapy. | 2020-12-01 |
| 33259429 | While improved handwashing techniques, social distancing, and other interventional measures may positively influence AMR, the widespread use of antibiotics to treat or prevent bacterial coinfections, especially in unconfirmed cases of COVID-19, may have unintended negative implications with respect to AMR. | 2020-12-01 |
| 33259441 | The aim of this study was to compare a diagnosis support system to detect COVID-19 pneumonia on chest radiographs (CXRs) against radiologists of various levels of expertise in chest imaging. […] The proposed system achieved higher overall diagnostic accuracy (94.3%) than the radiologists (61.4% ± 5.3%). | 2020-12-01 |
| 33259936 | Left ventricular angiography showed decreased with hypercontractile ventricular bases and mid-apical ballooning, consistent with diagnosis of Takotsubo syndrome. | 2020-12-01 |
| 33259955 | Molecular testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the mainstay for accurate diagnosis of the infection, but the diagnostic performances of available assays have not been defined. […] We compared 12 molecular diagnostic assays, including 8 commercial kits using 155 respiratory samples (65 nasopharyngeal swabs, 45 oropharyngeal swabs, and 45 sputum) collected at two Japanese hospitals. | 2020-12-01 |
| 33259980 | Content categories included Diagnostic Approach, Specific Imaging Diagnoses, Noninterpretive Skills, and Special Topics. […] The most popular episode discussing COVID-19 diagnosis and imaging, emphasized the importance of selecting high yield content to match listener needs. | 2020-12-01 |
| 33260013 | Current evidence suggests a decrease in elective diagnostic imaging procedures during the COVID-19 pandemic with potentially severe long-term consequences. […] Decrease in public interest coupled with delays and deferrals of diagnostic imaging will likely result in a high demand for healthcare in the coming months. | 2020-12-01 |
| 33260122 | When confronted with choices in terms of differential diagnosis and tests, the rigor of a simple application of the Bayesian framework can minimize costs arising from uncertainties. | 2020-12-01 |
| 33260236 | Data regarding clinical investigation, laboratory investigation, diagnosis, and treatment measures of 21 COVID-19 patients with spontaneous pneumothorax from January to March of 2020 were collected and analyzed in this study. | 2020-12-01 |
| 33260480 | Different diagnostic tools, such as Chest X-ray (CXR), lung ultrasound (LUS), and computerized tomography (CT), have been used to detect active pneumonic lesions associated with COVID-19 with their varying degrees of sensitivity and specificity. | 2020-12-02 |
| 33260639 | To perform a meta-analysis to evaluate the diagnostic performance of chest CT, common CT morphological abnormalities, disease prevalence, biodata information, and gender prevalence of patients. | 2020-12-02 |
| 33260778 | Descriptive, regression, and correlation analysis were used in the analytical processing, while the analyses included students’ scores in three diagnostic tools (Perceived Stress Scale (PSS), Patient Health Questionnaire for depression (PHQ 9), and Alcohol Use Disorders Identification Test (AUDIT)), as well as gender and income characteristics. | 2020-12-02 |
| 33260987 | -tests) the CBCL scores during lockdown with previous ones, and (ii) investigate the influence (multiple linear regression models) of variables such as age, diagnosis grouping (neurological, neurodevelopmental, emotional, and behavioural disorders) and financial hardship. | 2020-12-02 |
| 33261356 | The unavailability of vaccines, delays in diagnosis of the disease, and lack of proper treatment resources are the leading causes of the rapid spread of COVID-19. | 2020-12-02 |
| 33261629 | Reverse Transcription-Polymerase Chain Reaction (RT-PCR) for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) diagnosis currently requires quite a long time span. […] A quicker and more efficient diagnostic tool in emergency departments could improve management during this global crisis. | 2020-12-02 |
| 33261717 | Serologic tests must be carefully evaluated to assess coronavirus disease spread and immunity in tropical regions. | 2020-12-02 |
| 33261820 | Veterans with a previous PTSD clinical diagnosis were more likely to receive COVID-19 testing than veterans without PTSD. […] However, among those with available COVID-19 test results (n = 168,032), veterans with a previous PTSD clinical diagnosis were less likely to test positive than veterans without PTSD. | 2020-12-02 |
| 33261988 | The accelerated research activity in the development of diagnostic kits for SARS-CoV-2 is in progress for the rapid sequencing of various strains of SARS-CoV-2. | 2020-12-02 |
| 33262051 | As part of the BSc (Hons) Diagnostic Radiography programme students learn and undertake research relevant to their development as first post radiographers (dose optimisation and image quality) within the Research-Informed Teaching experience (RiTe). | 2020-12-02 |
| 33262093 | A positive COVID-19 polymerase chain reaction swab test, or symptoms (fever > 37.5 °C, upper respiratory tract symptoms, chest pain, and contact/travel history) associated with interstitial pneumonia on chest computed tomography scan were considered diagnostic of COVID-19 disease. | 2020-12-02 |
| 33262205 | The aim of this review is to summarize the clinical presentation, diagnosis, and outcomes of COVID-19 in pregnant women and neonates, who may be especially vulnerable to the effects of COVID-19, and to discuss what is known about potential maternal-fetal and maternal-neonatal transmission of SARS-CoV-2. | 2020-12-02 |
| 33262681 | With the diagnosis of SARS-CoV-2, he was treated based on the national protocol and stayed in the home quarantine for two weeks. […] Following the diagnosis of moderate airsickness, he was abstained from flying and treated with different prevention and rehabilitation techniques. | 2020-12-02 |
| 33262796 | Computed tomography (CT) scan plays an important role in the early diagnosis of coronavirus disease (COVID-19) pneumonia. […] In resource-limited regions with limited availability of polymerase chain reaction (PCR) kits, CT findings, together with appropriate clinical parameters, are used to establish an accurate diagnosis. […] Diagnosis based on radiological features can be especially challenging in the presence of a comorbid lung disease. | 2020-12-02 |
| 33262928 | Lung Ultra-Sound (LUS) can be very helpful at the diagnostic stage of COVID-19 pneumonia. | 2020-12-02 |
| 33262931 | The decline in the diagnostic testing kits supply chained to increased interest in 3D printed Nasopharyngeal (NP) swabs. | 2020-12-02 |
| 33263106 | Patients were divided into two subgroup: those with or without clinical and/or laboratory diagnosis of COVID-19. | 2020-12-02 |
| 33263109 | In total, 404 patients were included for final analysis with a COVID-19 diagnosis being made in 114 (28.2%) patients. | 2020-12-02 |
| 33263111 | Although neither an effective, clinically proven antiviral agents’ strategy nor an approved vaccine exist to eradicate the COVID-19 pandemic, there are alternatives that may reduce the huge burden on not only limited healthcare systems but also the economic sector; the most promising include harnessing non-clinical techniques such as machine learning, data mining, deep learning and other artificial intelligence. […] These alternatives would facilitate diagnosis and prognosis for 2019-nCoV pandemic patients. | 2020-12-02 |
| 33263129 | The observational study included consecutive patients admitted to a large community teaching hospital with a diagnosis of SARS-CoV-2 between March 6, 2020 and March 31, 2020. | 2020-12-02 |
| 33263485 | This article explores the essential statistical concepts used to interpret the findings of diagnostic investigations, with examples illustrated using COVID-19 antibody tests. | 2020-12-02 |
| 33263635 | This review presents an update on the diagnostic methods for COVID-19, including reverse-transcriptase polymerase chain reaction (RT-PCR) tests, serology tests, and imaging, and summarizes the current recommendations for the management of the disease. […] The diagnostic criteria and management of MIS-C are also summarized. | 2020-12-02 |
| 33263648 | Questionnaires were used to assess TMD symptoms in accordance with the Diagnostic Criteria for Temporomandibular Disorders: clinical protocol and assessment instruments, a questionnaire to verify oral behaviors and Hospital Anxiety and Depression Scale to assess symptoms of anxiety and depression in students of dentistry at the Faculty of Health Sciences of the University of Brasília in May 2020. | 2020-12-02 |
| 33264056 | During the initial stages of an outbreak, laboratory response capacity focuses on expansion of efficient diagnostic tools for rapid case detection, contact tracing, putting epidemiological findings into sources, mode of transmission, and identification of susceptible groups and reservoirs. […] It is important for public health diagnostic laboratories to have a fundamental knowledge of viral shedding, antibody response kinetics, assay validation, interpretation, and uncertainties of test results. | 2020-12-02 |
| 33264337 | Subjects admitted to 11 designated public hospitals in Taiwan between April 1 and May 31, 2020, with COVID-19 diagnosis confirmed by pharyngeal real-time RT-PCR for SARS-CoV-2, were randomized at a 2:1 ratio and stratified by mild or moderate illness. | 2020-12-02 |
| 33264366 | For all enrolled patients, longer duration from diagnosis to admission (odds ratio [OR] 1.108, 95% CI 1.022-1.202; P = 0.013), pulse oxygen saturation at admission <93% (OR 5.775, 95% CI 1.257-26.535; P = 0.024), higher neutrophil count (OR 1.495, 95% CI 1.177-1.899; P = 0.001) and higher creatine kinase-MB level at admission (OR 2.449, 95% CI 1.089-5.511; P = 0.030) were associated with a higher risk, whereas higher lymphocyte count at admission (OR 0.149, 95% CI 0.026-0.852; P = 0.032) was associated with a lower risk of critical illness development. | 2020-12-02 |
| 33264390 | These have been used for studying the prevalence and spread of infection in different populations, helping establish a recent diagnosis of coronavirus disease 2019 (COVID-19), and will likely be used to confirm humoral immunity after infection or vaccination. | 2020-12-02 |
| 33264484 | With the increasing understanding of COVID-19, changes have been made in aetiology, epidemiology, pathology, clinical features, diagnostic criteria, clinical classification, and treatment. | 2020-12-02 |
| 33265901 | These properties allow them to be used as an element of biosensors for the detection of specific proteins, including viral ones, which makes it possible to design valuable diagnostic tools. […] Therefore, a diagnostic solution is needed that will allow distinguishing between both pathogens, with high sensitivity and specificity; it should be cheap, quick and possible to use in the field, for example, in a doctor’s office. | 2020-12-03 |
| 33267587 | Diagnosis of COVID-19 has been challenging owing to the need for mass testing and for combining distinct types of detection to cover the different stages of the infection. […] In this review, we have surveyed the most used methodologies for diagnosis of COVID-19, which can be basically categorized into genetic-material detection and immunoassays. […] Detection of genetic material with real-time polymerase chain reaction (RT-PCR) and similar techniques has been achieved with high accuracy, but these methods are expensive and require time-consuming protocols which are not widely available, especially in less developed countries. | 2020-12-03 |
| 33267767 | In this review, the existing understanding of fatal, pandemic human coronavirus SARS-Cov2 (COVID-19), with special reference to its diagnosis, origin, transmission, and different approaches to develop its therapeutics, will be discussed. | 2020-12-03 |
| 33267785 | A total of 185 pregnant women infected with SARS-CoV-2 were enrolled with a median age of 31 years (interquartile range, IQR: 27.5-34), and median gestational age at diagnosis of SARS-CoV2 infection was 29 weeks (IQR: 18-34). | 2020-12-03 |
| 33267836 | Anosmia and ocular pain were symptoms independently associated with COVID-19 diagnosis. | 2020-12-03 |
| 33267892 | All the planned techniques were performed in 94.9% and the bronchoscopist was satisfied in 96.6% of the bronchoscopies. | 2020-12-03 |
| 33268329 | All identified cases were enrolled in a telehealth monitoring service, and symptoms were systematically monitored from diagnosis to recovery. […] At the time of diagnosis, 83 (5.3%) individuals reported no symptoms, of whom 49 (59%) remained asymptomatic during follow-up. […] At diagnosis, 216 (14%) and 349 (22%) people did not meet the case definition of the Centers for Disease Control and Prevention and the World Health Organization, respectively. […] A substantial proportion of SARS-CoV-2-positive people did not meet recommended case definitions at the time of diagnosis. | 2020-12-03 |
| 33268939 | The ongoing COVID-19 pandemic has hugely impacted the economy of many countries, and there is an acute shortage of diagnostic resources. […] With the exponential increase in the number of cases and necessity to screen large number of people, there is a steep increase in the demand for diagnostic kits. […] Medline, Google Scholar, Embase, and preprint servers (e.g., bioRxiv) were searched for literature on pooled testing for diagnosis of COVID-19, and out of initial 60 articles/reports, nine original articles were retained. | 2020-12-03 |
| 33269031 | Using recent advances in Bayesian spatial econometric techniques, we particularly focus on the time-dependent importance of alternative spatial linkage structures such as the number of flight connections, relationships in international trade, and common borders. | 2020-12-03 |
| 33269428 | The most standard diagnostic method is reverse transcription-polymerase chain reaction (RT-PCR) on a nasopharyngeal and/or an oropharyngeal swab. | 2020-12-03 |
| 33269683 | Disruptions to TB programs and healthcare services due to COVID-19 could potentially prolong diagnostic delays and worsen TB treatment adherence and outcomes. | 2020-12-03 |
| 33270005 | The ability to detect SARS-CoV-2 in saliva over a 1 week period is an important finding that presents further opportunities for saliva testing as a diagnostic specimen for the diagnosis of SARS-CoV-2. | 2020-12-03 |
| 33270029 | Visual analytics (VA) promotes the understanding of data with visual, interactive techniques, using analytic and visual engines. […] The analytic engine includes automated techniques, whereas common visual outputs include flow maps and spatiotemporal hot spots. […] This scoping review aims to address a gap in the literature, with the specific objective to synthesize literature on the use of VA tools, techniques, and frameworks in interrelated health care areas of population health and health services research (HSR). | 2020-12-03 |
| 33270044 | In addition to discussing the current epidemiological situation, diagnostic procedures, risk groups and COVID-19 characteristics, the paper presents recommendations and proposed solutions for employers and employees regarding the prevention of SARS‑CoV- 2, along with currently applicable laws and recommendations on employee prophylactic examinations during the pandemic. | 2020-12-03 |
| 33270166 | We guaranteed all urgent and semi-urgent examinations, including those to stage newly diagnosed cancers and to evaluate response to treatment, ensuring the continuation of the diagnostic and therapeutic pathway of our patients. | 2020-12-03 |
| 33270431 | Finally, clinical samples from COVID-19 patients led to a successful diagnosis. […] We anticipate that the current method can be employed for simple and accurate diagnosis of viruses. | 2020-12-03 |
| 33270719 | To evaluate the role of fasting blood glucose (FBG) to minimise the use of the oral glucose tolerance test in pregnancy (POGTT) for the diagnosis of gestational diabetes mellitus (GDM). […] Only 4,638 (17.7%) women having FBGs from 4.7-5.0mmol/l would require further evaluation to confirm or exclude the diagnosis. | 2020-12-03 |
| 33270741 | A total of 212 consecutive patients with a confirmed diagnosis of COVID-19 were compared with 185 medical patients from the previous year. | 2020-12-03 |
| 33270908 | Based on a diagnostic algorithm, patients with suspect symptoms underwent an infectious disease specialist’s evaluation and a COVID-19 swab. […] Serologic tests were proposed for patients who had symptoms or altered laboratory tests that did not fall into the diagnostic algorithm but were suspicious for COVID-19. […] Seventy-one patients (13%) had suspect symptoms and/or altered laboratory tests that were not included in the diagnostic algorithm and, of these, 47 patients (73%) underwent testing for severe acute respiratory syndrome coronavirus 2 antibody: 6 (13%) were positive for IgG (n = 5) or for both IgM and IgG (n = 1), and antibody tests were negative in the remaining 41 patients. […] The overall incidence of COVID-19 diagnosis (1%) and antibody positivity (13%) in patients with suspect symptoms was similar to that observed in the general population. | 2020-12-03 |
| 33271157 | CT is thought to play a key role in coronavirus disease 2019 (COVID-19) diagnostic workup. […] We aimed to prospectively validate the CO-RADS as a COVID-19 diagnostic tool at the ED and to evaluate whether the CTSS is associated with prognosis. […] Diagnostic accuracy measures were calculated for CO-RADS, using PCR as reference. […] Our findings support the use of CO-RADS and CTSS in triage, diagnosis, and management decisions for patients presenting with possible COVID-19 at the ED. | 2020-12-03 |
| 33271290 | We report two cases of Corona Virus Disease-19 (COVID-19) in patients with Down Syndrome (DS) and describe the identification, diagnosis, clinical course and management of the infection. | 2020-12-03 |
| 33271558 | Lung ultrasound (LUS) showed a promising role in the diagnosis and monitoring of patients hospitalized for novel coronavirus disease (COVID-19). […] The aim of this study was to evaluate the diagnostic and prognostic role of LUS in elderly patients hospitalized for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pneumonia. […] Thirty-seven hospitalized elderly patients (19 men) with a diagnosis of SARS-CoV-2 infection were consecutively enrolled. […] LUS could play a role in the diagnosis and prognosis in elderly patients hospitalized for SARS-CoV-2 infection. | 2020-12-03 |
| 33271595 | We included 168 691 people with a recorded diagnosis of RAIRD alive on 01/03/2020. | 2020-12-03 |
| 33272221 | Only 9 (18%) respondents declared uninterrupted bariatric surgery during a pandemic. 91% of surgeons declared continuation of bariatric care with telemedicine techniques. | 2020-12-04 |
| 33273040 | We constructed receiver-operating characteristic curves, calculated diagnostic parameters, and developed a multivariable model for predicting adverse outcome. | 2020-12-04 |
| 33273243 | The aims of the study were to review facial PPE (surgical masks and N95 respirators) ingredients, to identify facial PPE resterilization techniques, and to recommend strategies for prevention and management of facial PPE-related dermatoses. […] Resterilization techniques were identified. | 2020-12-04 |
| 33273713 | The diagnosis of severe acute respiratory syndrome 2 (SARS-CoV-2) infection by quantitative PCR with reverse transcription (RT-qPCR) typically involves bulky instrumentation in centralized laboratories and an assay time of 1-2 h. | 2020-12-04 |
| 33273714 | The inexpensive amplification-free detection of SARS-CoV-2 RNA should facilitate the rapid diagnosis of COVID-19 at the point of care. | 2020-12-04 |
| 33273946 | In the current review, we gathered and summarized the results of various studies on characteristics, diagnosis, treatment, and prevention of this pandemic crisis. | 2020-12-04 |
| 33274111 | Details of neurotrauma admissions under the neurosurgery department at our institute since the onset of COVID-19 pandemic in the country were collected retrospectively and compared to the same period last year in terms of demographic profile, mode of injury, GCS at admission, severity of head injury, radiological diagnosis, management (surgical/conservative), and outcome. | 2020-12-04 |
| 33274172 | Patients with such abscesses are often initially misdiagnosed or there is a significant diagnostic delay. | 2020-12-04 |
| 33274180 | Clinical experience with recurrent pregnancy loss offers workable interventions to address this challenge, but success will depend on prompt and accurate SARS-CoV-2 diagnosis. | 2020-12-04 |
| 33274292 | ID physicians acted as the patients and then conducted feedback sessions, which focused on PPE choice, donning and doffing techniques, and ID diagnosis and management principles. | 2020-12-04 |
| 33274357 | The HemoScreen analyzer demonstrates lab equivalent performance, tested at different clinical settings and sample characteristics, and might outperform standard techniques in the presence of certain interferences. | 2020-12-04 |
| 33274387 | We simulated facility-based isolation strategies with various capacities and starting times under different diagnosis rates. […] Facility-based isolation with high capacity of 10 beds per 10 000 population would achieve greater reduction of 76% (62-84%) in new infections and 52% (37-64%) in deaths when supported by the expanded testing with a 20% daily diagnosis rate. | 2020-12-04 |
| 33274414 | All adult patients with a COVID-19 diagnosis between March 1, 2020, and April 12, 2020, in 10 hospitals in Massachusetts, USA. | 2020-12-04 |
| 33274416 | In the future, this could help in triage, diagnosis and early management. | 2020-12-04 |
| 33274432 | The data was collected through direct care, written conversations, physical communication, observation, medical record reviews, diagnosis reports, and nursing assessments of physical, psychological, social, and spiritual distress. | 2020-12-04 |
| 33274617 | Cervical intraepithelial neoplasia 3 and high-grade squamous intraepithelial lesions should be treated immediately after diagnosis using at least a loop electrosurgical excision procedure while any major surgery should be postponed by 10-12 weeks. […] Vulvar and vaginal cancers can be treated within 10-12 weeks of diagnosis, but radiotherapy should be given in preference in this situation. | 2020-12-04 |
| 33274782 | In symptomatic medical inpatients with known or suspected COVID-19, we recommend the use of LUS to: (1) support the diagnosis of pneumonitis but not diagnose COVID-19, (2) rule out concerning ultrasound features, (3) monitor patients with a change in the clinical status, and (4) avoid unnecessary additional imaging for patients whose pretest probability of an alternative or superimposed diagnosis is low. | 2020-12-04 |
| 33275187 | Hence, Deep Learning and Image Classification techniques can be employed to learn from these irregularities, and classify accordingly with high accuracy. […] Also, this research demonstrates handling data imbalance using various techniques involving Generative Adversarial Networks and sampling techniques. | 2020-12-04 |
| 33275578 | During the COVID-19 pandemic, an ultra-portable ultrasound smart probe has proven to be one of the few practical diagnostic and monitoring tools for doctors who are fully covered with personal protective equipment. | 2020-12-04 |
| 33275588 | Real-time reverse transcription polymerase chain reaction (rRT-PCR) and chest computed tomography (CT) imaging both play an important role in COVID-19 diagnosis. | 2020-12-04 |
| 33276017 | We present evidence supporting early intervention immediately following a positive diagnosis via inhaled delivery of mAbs with vibrating mesh nebulizers as a promising approach for the treatment of COVID-19. | 2020-12-04 |
| 33276252 | Following a comparison of different propensity score weighting methods, overlap propensity score weighting was used to analyze the association between medication use and COVID-19 diagnosis. | 2020-12-04 |
| 33276318 | Preventing overcrowding in the ED is key to reducing the risk of disease transmission, and teleconsulting practice is thought to be effective in the diagnosis, treatment, and reduction of transmission risk of disease, most notably during the COVID-19 pandemic. | 2020-12-04 |
| 33276520 | More than half of the students met the diagnostic criteria of GAD (52%) and depression (63%). | 2020-12-05 |
| 33276612 | The aim of this review is to highlight the impact of such a “de-prioritization” of cataract surgery and to summarize some critical issues and useful hints on how to reorganize cataract pathways, with a special focus on perioperative diagnostic tools during the recovery phase and beyond. | 2020-12-05 |
| 33276628 | : RTMUS echo allows for rapid access to diagnostic imaging in various clinical settings. | 2020-12-05 |
| 33276770 | When other procedures were performed during the encounter, the majority were diagnostic in nature, primarily radiographs. | 2020-12-05 |
| 33276839 | To analyze the cardiovascular disease (CVD) burden in hospitalized patients with a diagnosis of coronavirus from the pre-coronavirus disease 2019 era in the United States. […] We identified hospitalized adults with a diagnosis of coronavirus in a large US administrative database, the National (Nationwide) Inpatient Sample, from January 1, 2016, to December 3, 2017, to study patient demographic characteristics, clinical comorbidities, and outcomes (in-hospital mortality and health care resource utilization) based on the presence or absence of CVD. […] A total of 21,300 hospitalized adults with a diagnosis of coronavirus in 2016 and 2017 from all across the United States were included in the final analysis; the mean age was 63.6 years, 11,033 (51.8%) were female, and 15,911 (74.7%) had public insurers. […] Among these hospitalized patients, 11,930 (56.0%) had a diagnosis of CVD. | 2020-12-05 |
| 33277291 | Patients diagnosed with COVID-19 from 22 February 2020 to 17 May 2020 were followed from date of diagnosis until outcome of interest, death or 17 May 2020. […] Use of statins, defined as a redeemed drug prescription in the 6 months prior to COVID-19 diagnosis. | 2020-12-05 |
| 33277976 | The first version of the guidance was approved in June 2020, and consisted of 40 final guidance statements accompanied by a flow diagram depicting the diagnostic pathway for MIS-C. | 2020-12-05 |
| 33278049 | It is debated if skin lesions could represent a diagnostic or prognostic indicator. […] Specifically, it is unclear whether skin lesions may be used to perform an early diagnosis and/or to predict worse outcomes. […] In this review, we described the cutaneous signs so far reported as COVID-19-related and discussed their incidence, clinico-pathological features, and diagnostic and prognostic value. | 2020-12-05 |
| 33278088 | Bedside sonography became an important tool to manage the patient by adapting artificial ventilation parameters and played a key role in the diagnosis of thrombotic events and the monitoring of subarachnoid hemorrhage that unexpectedly complicated the case. | 2020-12-05 |
| 33278107 | A broad diagnostic approach is recommended, given overlapping presentations between MIS-C and many other disease processes. […] Several studies have described the clinical manifestations of MIS-C, but definitive diagnosis remains challenging. […] Robust information about long-term outcomes awaits further study, as do immunologic data to refine diagnostic and therapeutic strategies. | 2020-12-05 |
| 33278110 | The purpose of this review is to describe current diagnostic modalities for SARS-CoV-2 and outline their use. […] Antigen testing is being widely deployed as a faster and more convenient alternative to PCR, but is less sensitive and should only be used for diagnosis early after symptom onset. | 2020-12-05 |
| 33278301 | Patients with a physician-estimated prognosis from the underlying hematologic malignancy of <12 months at the time of COVID-19 diagnosis and those with relapsed/refractory disease experienced a higher proportion of moderate/severe COVID-19 disease and death. | 2020-12-05 |
| 33278329 | In the current climate this would help manage appropriate use of imaging resources during the post COVID-19 pandemic recovery phase, as well as support recommendations regarding diagnostic reform and a move towards more community-based diagnostics. | 2020-12-05 |
| 33278549 | Those with a current/past diagnosis of eating disorders reported significantly greater difficulties in regulating eating, increased preoccupation with food, exercise thoughts and behaviours and concern about appearance, even when compared to those with other mental health and developmental disorders. | 2020-12-05 |
| 33278644 | A COVID-19 diagnosis was made by transcriptase polymerase chain reaction by means of nasopharyngeal swab or by chest computer tomography (CT) without iodine contrast media. | 2020-12-05 |
| 33278737 | Several RT-qPCR kits are available for SARS-CoV-2 diagnosis, some of them with Emergency Use Authorization (EUA) by FDA, but most of them lacking of proper evaluation studies due to covid19 emergency. […] We evaluated Viasure RT-qPCR kit (CerTest Biotec, Spain) for SARS-CoV-2 diagnosis using FDA EUA 2019-nCoV CDC kit (IDT, USA) as a gold standard. […] Viasure RT-qPCR kit is a reliable tool for SARS-CoV-2 diagnosis but improvement of an alternative RT-qPCR reaction for RNA extraction quality control as RNaseP is recommended. | 2020-12-05 |
| 33278758 | During an outpatient follow-up visit, chest CT, pulmonary function and COVID-19 related symptoms were assessed approximately 10 weeks after diagnosis. […] Demographics, baseline (time of diagnosis) CT score and blood results were collected from patient files. […] Fifty-four percent of COVID-19 survivors had abnormal lung function 10 weeks after diagnosis. | 2020-12-05 |
| 33278855 | This paper aimed to review and analyse the published studies about COVID-19 diagnosis, prevention, and treatment. | 2020-12-05 |
| 33279106 | In addition, we describe inpatient and outpatient diagnosis-based algorithms to help select patients for telemedicine versus in-person evaluation. | 2020-12-06 |
| 33279331 | We sought to describe and characterize the impact of COVID-19 on hospital admissions through EDs, with a specific focus on diagnosis group, age, gender, and insurance coverage. […] The most common diagnosis during this time was SARS-CoV-2. | 2020-12-06 |
| 33279652 | Patients with a confirmed COVID-19 or Influenza diagnosis, for whom a complete hospital course was available (i.e., the patient was discharged or died in hospital) were included. | 2020-12-06 |
| 33279860 | Early diagnosis of coronavirus disease 2019 (COVID-19) is of the utmost importance but remains challenging. | 2020-12-06 |
| 33279989 | Various next generation sequencing (NGS) based strategies have been successfully used in the recent past for tracing origins and understanding the evolution of infectious agents, investigating the spread and transmission chains of outbreaks, as well as facilitating the development of effective and rapid molecular diagnostic tests and contributing to the hunt for treatments and vaccines. […] The development of efficient and rapid sequencing methods to reconstruct the genomic sequence of SARS-CoV-2, the etiological agent of COVID-19, has been fundamental for the design of diagnostic molecular tests and to devise effective measures and strategies to mitigate the diffusion of the pandemic. | 2020-12-06 |
| 33279995 | Automated text mining techniques for searching, reading and summarizing papers are helpful for addressing information overload. | 2020-12-06 |
| 33280141 | All patients with a neuromuscular junction disorder diagnosis code in the Duke Health System were invited to participate. | 2020-12-06 |
| 33280199 | Barrier techniques, such as plastic sheets or intubation boxes, are purported to offer additional protection for healthcare workers. […] To assess the functionality, perceived safety, droplet protection, and aerosol protection of several barrier techniques. […] Firstly, a simulation study with 12 different laryngoscopists was conducted to assess the time taken to perform an intubation (via direct laryngoscopy, via video laryngoscopy, and via a bougie) with four different barrier techniques (personal protective equipment only, a plastic sheet, a tented plastic sheet, and an intubation box). | 2020-12-06 |
| 33280213 | The evaluation of MPV and lymphocyte levels together could increase diagnostic success in asymptomatic COVID-19 patients. | 2020-12-06 |
| 33280586 | The scientific and medical communities are rallying to study different strains and probable mutations to develop more rapid and reliable molecular diagnostic tests and possible therapeutic approaches for SARSCoV-2. […] The next section summarizes the current diagnostic tests for COVID-19 such as nucleic acid and computed tomography (CT) techniques with further emphasizing on emerging diagnostic approaches for COVID-19. | 2020-12-07 |
| 33280767 | Here, we report the case of a 31-year-old patient with unexplained extensive DVT and bilateral pulmonary embolism in the absence of COVID-19 pneumonia, leading to the diagnosis of otherwise asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. | 2020-12-07 |
| 33281041 | Chest CT derived measurements were evaluated retrospectively for 217 patients with a diagnosis of COVID-19 pneumonia. | 2020-12-07 |
| 33281048 | Thus, we have successfully developed a SARS-CoV-2 NP-specific rapid diagnostic test, which is expected to be a simple and rapid diagnostic test for COVID-19. | 2020-12-07 |
| 33281082 | Although nucleic acid testing of SARS-CoV-2 is still the gold standard for diagnosis, there are well-recognized early-detection problems including time-consuming in the diagnosis process, noticeable false-negative rate in the early stage and lacking nucleic acid testing kits in some areas. […] Therefore, effective and rational applications of imaging technologies are critical in aiding the screen and helping the diagnosis of suspected patients. | 2020-12-07 |
| 33281114 | This study aimed to investigate the association between the change in laboratory markers during the three days after pneumonia diagnosis and severe respiratory failure in COVID-19 patients. […] The levels of hemoglobin (Hb) and albumin (Alb) decreased in the MV group during the three days after pneumonia diagnosis more than in the non-MV group (median Hb: 1.40 vs. -0.10 g/dL, P = 0.015; median Alb: 0.85 vs. -0.30 g/dL, P = 0.020). […] The decrease in Hb level during the short period after pneumonia diagnosis might be a predictor of worsening pneumonia in COVID-19 patients. | 2020-12-07 |
| 33281225 | The diagnostic pathway, treatment and clinical course of this rare disease are described. | 2020-12-07 |
| 33281415 | Inclusion criteria were (1) primary studies, (2) positive disease diagnosis (3) limb ischemia, (4) reported treatment. | 2020-12-07 |
| 33281434 | The reported research in facemasks has covered many of their material types, fabrication techniques, mechanism characterization, and application aspects. | 2020-12-07 |
| 33281589 | As infection, resulting illness, and the often prolonged recovery period continue to be characterized, therapeutic roles for transcranial electrical stimulation (tES) have emerged as promising non-pharmacological interventions. tES techniques have established therapeutic potential for managing a range of conditions relevant to COVID-19 illness and recovery, and may further be relevant for the general management of increased mental health problems during this time. […] Furthermore, these tES techniques can be inexpensive, portable, and allow for trained self-administration. […] Here, we summarize the rationale for using tES techniques, specifically transcranial Direct Current Stimulation (tDCS), across the COVID-19 clinical course, and index ongoing efforts to evaluate the inclusion of tES optimal clinical care. | 2020-12-07 |
| 33281824 | Illustrating human antibody responding to viral antigen could potentially provide valuable information for basic research and clinical diagnosis. […] The antibody can be used as a complement to the viral detection for the rapid diagnosis of infected patients. […] As a major antigen, NP is a potential target for the diagnosis of SARS-CoV-2 infection. […] Among these 16 antibodies, two well-paired antibodies were finally screened out for SARS-CoV-2 diagnosis by double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) method. […] Our works may provide a potential resource for the clinical diagnosis of SARS-CoV-2 infection. | 2020-12-07 |
| 33282072 | These cases demonstrate that viral shedding after COVID-19 diagnosis can be prolonged. | 2020-12-07 |
| 33282076 | So far, the real-time reverse transcriptase-polymerase chain reaction (RT-qPCR) is the assay of choice for COVID-19 diagnosis considering its rapidity and accuracy in informing on active coronavirus (CoV) infection. […] This review provides a critical assessment of various published works on RT-qPCR assays used for COVID-19 diagnosis with their different indicators of positivity i.e., cycle threshold (Ct) cut-off values. […] Knowledge of diagnostic tests for COVID-19 is still evolving and, as a prospect, underscores the need for local validation of positive-negative Ct cut-off values when establishing RT-qPCR assays for SARS-CoV-2 detection. | 2020-12-07 |
| 33282093 | The testing capacity for COVID-19 diagnosis in Africa is grossly inadequate coupled with a severe shortage of personal protective equipment and inadequate infectious diseases expert. | 2020-12-07 |
| 33282166 | This cross-sectional study reports on the baseline complete blood count in patients attending publicly funded primary care settings with a diagnosis of suspected COVID-19 infections in the state of Qatar. […] Nine hundred sixty-two adult patients attended publicly funded primary health care settings in the state of Qatar between February the 10th and April the 30th 2020 with a diagnosis of suspected COVID-19 infections had prior recorded blood investigations in the last six months and were included in this study. | 2020-12-07 |
| 33282198 | However, definitive diagnosis of pulmonary hypertension is difficult because of the risk of spreading the infection. | 2020-12-07 |
| 33282582 | We report the first case of a thyrotoxic crisis precipitated by COVID-19 and describe its identification, diagnosis, and management in the emergency unit. | 2020-12-07 |
| 33282650 | Once she tested positive, she was hospitalized in the pneumological department with a diagnosis of pneumonia based on a chest X-ray and biochemical tests. […] This case highlights the fact that, in a pandemic situation, there is a potentially fatal risk of overlooking an alternative diagnosis in a COVID-19 patient who is generally considered as suffering only from pneumonia. | 2020-12-07 |
| 33282675 | Inactivation of SARS-CoV-2 in WWTPs depends on the operational parameters and is generally enhanced by the tertiary treatment and disinfection techniques with a higher dosage. | 2020-12-07 |
| 33282717 | Aortic dissection is one of the major life-threatening diseases that needs to be identified early on in the emergency department; however, in this case delayed diagnosis raised significant concerns due to underlying evolving triaging system for COVID-19 and atypical and overlapping clinical presentation. | 2020-12-07 |
| 33282810 | Korean biotech firms promptly developed diagnostic test kits, and the nation achieved capacity to test more than 20,000 people daily. | 2020-12-07 |
| 33282890 | Reverse transcriptase-Polymerase chain reaction (RT-PCR) is a diagnostic test of choice for SARS CoV-1, MERS-CoV, and SARS CoV-2 infections. […] This review aims to discuss epidemiological, clinical features, diagnosis, and management of human coronaviruses with a focus on SARS CoV-1, MERS-CoV, and SARS CoV-2. | 2020-12-07 |
| 33283031 | Chest CT findings have been described as an aid for COVID-19 diagnosis and management. | 2020-12-07 |
| 33283161 | This review is an update on the mechanisms underlying TTS, its diagnosis, and its optimal management. | 2020-12-07 |
| 33283230 | Because of the rapidly emerging SARS-CoV-2 pandemic and its wide public health challenges, rapid diagnosis is essential to decrease the spread. […] Poor sensitivity of the BIOCREDIT COVID-19 test does not permit its use for diagnosis, and it can only be used in conjunction with RT-PCR for screening. | 2020-12-07 |
| 33283237 | Cross-sectional multicenter study including all diagnosis of KD, myocarditis and multisystem inflammatory syndrome in children (MIS-C) from February to April,2020. | 2020-12-07 |
| 33283554 | : The SARS-CoV-2 pandemic had a profound negative effect on the diagnostic output of our centralized molecular diagnostics center. | 2020-12-07 |
| 33283759 | Since the beginning of the pandemic, laboratory diagnostic methods have evolved substantially, and with them has been the necessity for readily available, fast, and accurate preoperative testing methods. | 2020-12-07 |
| 33283840 | It has also provided guidance for diagnostic testing and has described immune and virologic correlates with disease severity. | 2020-12-07 |
| 33283979 | Highlights Our multicenter study reports a higher proportion of diabetic ketoacidosis presentation of over 60% in newly diagnosed patients with type 1 diabetes with or without confirmed coronavirus disease 2019 (COVID-19) at diagnosis. | 2020-12-07 |
| 33284396 | When FNAs are properly requested by endocrinologists for nodules characterised by relevant clinical and ultrasound features, cytopathologists play a pivotal role in the diagnostic work-up. […] Conversely, improper FNA requests can lead to questionable diagnostic efficiency. […] Recently, recommendations to delay all non-urgent diagnostic procedures, such as thyroid FNAs, to contain the spread of COVID-19 infection, have made the interplay between endocrinologists and cytopathologists even more essential. | 2020-12-07 |
| 33284510 | Changes in engaged personnel were encountered between the two surveys, along with increasing use of advanced echocardiographic techniques (23.1% in 2018 vs. | 2020-12-07 |
| 33284778 | The majority of respondents (n=1335, 96.4%) were confident about their doctor’s expertise in terms of COVID-19 diagnosis and treatment, which was positively associated with less distress caused by the outbreak (B=-7.84, 95% CI -14.58 to -1.11). | 2020-12-07 |
| 33284779 | Thus, it is the first review that describes and summarizes features of the identified AI techniques and data sets used for their development and validation. | 2020-12-07 |
| 33284780 | Our overarching goal is to evaluate the efficacy and usability of web-based peer-learning for advanced suturing techniques (ie, running subcuticular sutures). […] The students will view eight videos and rate the surgical techniques using the Objective Structured Assessment of Technical Skills Global Rating Scale and the Subcuticular Suture Checklist as evaluation criteria. | 2020-12-07 |
| 33284987 | A total of 1523 patients with a current or past diagnosis of solid tumors and diagnosed with COVID-19 (confirmed with PCR) between 11 March and 20 May 2020 were included. […] Seventy-seven (5.1%) patients died within 30 days of diagnosis. | 2020-12-07 |
| 33285190 | Following the declaration of the outbreak as a Public Health Emergency of International Concern by the World Health Organization (WHO) on January 30th, 2020, it has become imperative to develop diagnostic tools to reliably detect the virus in infected patients. […] In addition, these methods have been recommended by the WHO for laboratory diagnosis. […] Since most of these protocols are based on the use of fluorogenic probes and one-step reagents (cDNA synthesis followed by PCR amplification in the same tube), these techniques can be difficult to perform given the limited supply of reagents in low- and middle-income countries. | 2020-12-07 |
| 33285191 | Here we offer a Hong Kong perspective on different aspects of the pandemic virus (SARS-CoV-2) and the disease : public health (diagnosis and control), food safety (reducing transmission in the workplace) and animal vectors (controlling potential reservoirs of the virus and their movements). | 2020-12-07 |
| 33285279 | Seroprevalence with a high-quality diagnostic in Germany seemed to be around 2%. | 2020-12-07 |
| 33285285 | Accuracy testing demonstrated excellent assay agreement between expected and observed values and comparable diagnostic performance to reference tests. | 2020-12-07 |
| 33285482 | The efficient diagnosis of COVID-19 plays a key role in preventing the spread of this disease. […] The computer-aided diagnosis with deep learning methods can perform automatic detection of COVID-19 using CT scans. […] The COVID-AL consists of the lung region segmentation with a 2D U-Net and the diagnosis of COVID-19 with a novel hybrid active learning strategy, which simultaneously considers sample diversity and predicted loss. […] The experimental results demonstrate that the proposed COVID-AL outperforms the state-of-the-art active learning approaches in the diagnosis of COVID-19. | 2020-12-07 |
| 33285550 | The receiver operating characteristic (ROC) curve was used to evaluate diagnostic accuracy. | 2020-12-07 |
| 33285678 | According to the fourth version of the guidelines on the Diagnosis and Treatment of COVID-19 by the National Health Commission of China, patients were divided into subgroups according to disease severity (moderate and severe/critical) or age (<40 years, 40-64 years and ≥65 years). | 2020-12-08 |
| 33285727 | COVID-19 has the characteristics of rapid transmission, atypical clinical symptoms, easy missed diagnosis and misdiagnosis, and so on. which has seriously affected social and economic development and people’s health. | 2020-12-08 |
| 33285740 | Diagnosis of severe COVID-19 infectious pneumonia was established by travel history, clinical features, chest imaging, and a positive oropharyngeal swab specimen result for the severe acute respiratory syndrome coronavirus 2 RT-PCR assay. | 2020-12-08 |
| 33286803 | This approach, after further studies, or combined with more measures such as Sample Entropy, is certainly very promising in becoming an early diagnosis tool based solely on body temperature temporal patterns, which is of great interest in the current Covid-19 pandemic scenario. | 2020-12-08 |
| 33287199 | Given the novelty of the virus causing this pandemic, it has not been easy to address diagnostic and management issues in PE. | 2020-12-08 |
| 33287732 | We evaluated LUS as a rapid diagnostic triage tool for the management of patients with suspected COVID-19 in the emergency department (ED). | 2020-12-08 |
| 33287821 | COVID-19 surveillance is challenged by delayed or absent clinical symptoms and imperfect diagnostic sensitivity of standard RT-PCR tests. | 2020-12-08 |
| 33287943 | Early diagnosis and isolation of mild or asymptomatic COVID-19 patients is important to control the spread of SARS-CoV-2. […] In this study, we investigate the potential clinical utility of lymphocyte CPD for early diagnosis of COVID-19. […] To investigate the potential of lymphocyte cell population data (lymphocyte CPD) for use in early diagnosis of coronavirus disease 2019 (COVID-19). […] The parameters were subjected to sensitivity and specificity analysis to determine their suitability as biomarkers for early diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. […] These results suggest that lymphocyte CPD parameters have great diagnostic potential for SARS-CoV-2 infection and can be used for early diagnosis of the disease. | 2020-12-08 |
| 33288350 | The potential for home diagnosis and monitoring could reduce infectious risk for other patients and health care providers, limit use of finite hospital resources, and enable better social distancing and isolation practices. […] Her clinical picture and typical lung findings of COVID-19 on ultrasound, combined with a normal echocardiogram and negative deep vein thrombosis study, helped inform her diagnosis. […] Her diagnosis was confirmed with a positive IgG antibody test after 3 weeks. […] Novel times call for novel solutions and our case demonstrates one possible path for home diagnosis and monitoring of COVID-19. | 2020-12-08 |
| 33288661 | Here, we characterize the IgA response to SARS-CoV-2 in a cohort of 149 convalescent individuals after diagnosis with COVID-19. | 2020-12-08 |
| 33288981 | In this study, the use of lung ultrasonography (LUS) to diagnosis lung findings was evaluated in patients with suspected COVID-19 who were admitted to the emergency department (ED). […] The sensitivity of LUS in the diagnosis of pneumonia in the COVID-19 patients was 62.5%, while its specificity was 62.5%. […] LUS may also be used in the diagnosis of pneumonia in COVID-19 patients because it is a valuable and accessible bedside diagnostic tool. | 2020-12-08 |
| 33288986 | After about 1 year of Corona-virus pandemic, it still presents with some rare pulmonary and extrapulmonary manifestations, so, familiarity with these manifestations is important for a correct diagnosis and treatment. | 2020-12-08 |
| 33288999 | Computer tomographic scan of the chest is a principal diagnostic measure for Corona Virus Disease 2019 (COVID-19). | 2020-12-08 |
| 33289143 | Serological detection of SARS-CoV-2-specific antibody is usually limited to immunoglobulin (Ig)M, IgG and total antibodies, comprising IgA, IgM and IgG.IgA antibodies are less frequently used for SARS-CoV-2 detection as IgM and IgG-based assays are the gold standard for serological diagnosis. | 2020-12-08 |
| 33289151 | The diagnosis of COVID-19 is well defined, but efficacious treatment is lacking. | 2020-12-08 |
| 33289157 | This paper seeks to elaborate on the potential application of IgM and IgG antibodies and the viral antigens for the diagnosis and the course of the disease as well as the recurrence of positive nucleic acid tests after discharge. | 2020-12-08 |
| 33289192 | Understanding the immune response dysregulation in COVID-19 is essential to develop more effective diagnostic, therapeutic, and prophylactic strategies in this pandemic. | 2020-12-08 |
| 33289365 | Further investigations are needed to utilize DXR more effectively and to establish it as a valuable diagnostic tool. | 2020-12-08 |
| 33289485 | While symptoms associated with HE were reported by 29.9% (149/499) of patients, the actual diagnosis of HE was reported less frequently by 11.2% (53/473) with a median duration of 120 days. | 2020-12-08 |
| 33289545 | This reference standard was then used to challenge the LoDs of six officially approved diagnostic assays. | 2020-12-08 |
| 33289913 | This includes, among other things, which patients can be treated in the clinic, how registration is carried out, how the diagnosis is carried out and which treatment strategies are available. | 2020-12-08 |
| 33289923 | The analysis included epidemic curves, temporal-spatial distribution, clinical classification and interval times between onset and diagnosis. […] The median of the interval in paediatric cases between onset and diagnosis, isolation and notification were 3, 0 and 3 days, respectively, and all of those were significantly shorter than in adults. | 2020-12-08 |
| 33289964 | This study evaluated the role of eosinopenia as a diagnostic and prognostic indicator in COVID-19 infection. […] Eosinopenia for early diagnosis of COVID-19 had a sensitivity of 80.68% and specificity of 100% with an accuracy of 85.24. […] Eosinopenia on admission is a reliable and convenient early diagnostic marker for COVID-19 infection, helping in early identification, triaging and isolation of the patients till nucleic acid test results are available. | 2020-12-08 |
| 33290144 | Moreover, the signature presented an excellent diagnostic power in differentiating HCC and normal tissues. | 2020-12-08 |
| 33290245 | Inclusion criteria includes the capacity to consent; a primary diagnosis of generalized anxiety disorder or major depressive disorder, with symptoms that started or worsened during the COVID-19 pandemic; the ability to speak and read English; and consistent and reliable access to the internet. | 2020-12-08 |
| 33290293 | Baseline laboratory tests other than SARS-CoV-2 reverse transcription polymerase chain reaction were not diagnostic; the mean absolute lymphocyte count was 8.7±2.4×10/L. | 2020-12-08 |
| 33290427 | Healthcare workers are directly involved in the prevention, diagnosis, treatment, and care of patients with COVID-19. | 2020-12-08 |
| 33290544 | A high proportion of tested children with SARS-CoV-2 infection had evidence of complement activation and met clinical and diagnostic criteria for TMA. | 2020-12-08 |
| 33290570 | In this article, we review available evidence and approaches for vaccine communication, including the importance of using a whole-team approach, building trust, starting the conversation early, using a presumptive approach for vaccine recommendations, motivational interviewing with parents who have concerns for vaccines, and additional techniques for responding to parent questions. | 2020-12-08 |
| 33291059 | Prevalence of self-reported flu diagnosis in adults age 18-64 who received the flu vaccine between September 1, 2019 and April 15, 2020 (n = 3,225) was 5.8 %, while self-reported flu or flu-like illness (without a flu diagnosis) was 17.9 %. | 2020-12-08 |
| 33291193 | Ultrasound has several advantages including no ionizing radiation exposure for health care workers, being a safe, fast and non-invasive diagnostic technique with bedside usage. […] Hence, ultrasound is an efficient alternative to diagnosis and monitor of patients with COVID-19 pneumonia. | 2020-12-09 |
| 33291194 | One hundred and forty-four patients with the diagnosis of COVID-19, confirmed by Rt-PCR (reverse transcription-polymerase chain reaction), were restrospectively reviewed. | 2020-12-09 |
| 33291238 | Early and accurate diagnosis of ARDS depends upon clinical suspicion and chest imaging. […] Coronavirus disease 2019 (COVID-19) is an important novel cause of ARDS with a distinct time course, imaging and laboratory features from the time of SARS-CoV-2 infection to hypoxemic respiratory failure, which may allow diagnosis and management prior to or at earlier stages of ARDS. […] Future improved clinical outcomes in ARDS of all causes depends upon individual patient physiological and biological endotyping in order to improve accuracy and timeliness of diagnosis as well as optimal targeting of future therapies in the right patient at the right time in their disease. | 2020-12-09 |
| 33291619 | PIMS-TS is a new disease developed in a small percentage of patients, so a high degree of suspicion is necessary to establish the diagnosis. | 2020-12-09 |
| 33291638 | Moreover, the implementation of molecular diagnostic tools, which were initially absent, enabled health care experts to make quick diagnoses. | 2020-12-09 |
| 33291710 | Background The use of computed tomography (CT) for coronavirus disease 2019 (COVID-19) diagnosis in an area of northern Italy with a high incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may have identified more patients with this disease than RT-PCR in the very early onset of the COVID-19 pandemic. […] Results Among 32 patients with a diagnosis of COVID-19, 17 patients were asymptomatic or had mild symptoms (53.1%), while 15 developed severe disease (46.8%). | 2020-12-09 |
| 33291719 | Four papers were aimed at assessing patients and health practitioners experiences about Teledentistry, three studies reported a cost analysis and cost description of Teledentistry in residential aged care facilities, and two studies investigated the feasibility and accuracy of Teledentistry for diagnosis dental pathology. | 2020-12-09 |
| 33291722 | Because of the latent existing risk of facing another pandemic like the one we are living through due to COVID-19, researchers are constantly looking forward to developing new technologies for diagnosis and treatment of infections caused by different bacteria and viruses. […] Therefore, this work aims to present a comprehensive review that exposes how biosensors work in terms of bacterial and viral detection, and the nanotechnological features that are contributing to achieving a faster yet still efficient COVID-19 diagnosis at the point-of-care. | 2020-12-09 |
| 33291791 | This laboratory finding could help to identify patients at high-risk of COVID-19 in the setting where gold standard diagnostic methods are not available. | 2020-12-09 |
| 33292336 | This paper thoroughly summarizes interdisciplinary notions and techniques, including disease model, biochip, network pharmacology, and molecular docking technology, etc., providing a reference for researchers in the screening of drugs for COVID-19 prevention and treatment. | 2020-12-09 |
| 33292370 | We explore COVID-19 treatment service options at the patient level (diagnosis, management, location and level of treatment) and measures to reduce nosocomial transmission (cohorting patients, protecting healthcare workers). | 2020-12-09 |
| 33292536 | The number of COVID-19 deaths and the COVID-19 mortality rate per million were calculated for hospitals, nursing homes and other places of death, according to diagnostic status (confirmed/possible infection). | 2020-12-09 |
| 33292579 | This is of particular salience as face-to-face healthcare and traditional frontline interventions are disrupted, and we are challenged to re-design our practices to deliver diagnostic and treatment services in highly adaptive digital contexts. | 2020-12-09 |
| 33292820 | Therefore, COVID-19 is a new differential diagnosis to bear in mind when evaluating patients with musculoskeletal symptoms and rheumatologists might play a crucial role in identifying COVID-19 cases in early phases of the illness. | 2020-12-09 |
| 33292922 | Three cases occurred concomitantly with COVID-19 diagnosis; 1 occurred on day 15 of intensive care. | 2020-12-09 |
| 33293201 | This study aims to investigate the efficacy of a brief online form of Emotional Freedom Techniques (EFT) in the prevention of stress, anxiety, and burnout in nurses involved in the treatment of COVID patients. | 2020-12-09 |
| 33293326 | Early diagnosis of these cases is a powerful tool to control the pandemic. | 2020-12-09 |
| 33293424 | (ICD-10-CM) diagnosis codes occurring before and after the onset of the COVID-19 pandemic in an exposure-crossover design. […] We included patients who received a diagnosis of COVID-19 between Mar. 1, 2020, and Apr. 30, 2020, and computed risk estimates and odds ratios (ORs) of association with COVID-19 for every ICD-10-CM diagnosis code. […] Among 70 288 patients with COVID-19, 69 of 1724 analyzed ICD-10-CM diagnosis codes were significantly associated with COVID-19. | 2020-12-09 |
| 33294105 | The review shows that, at present, antibodies have little use in the diagnosis of COVID-19 within the first seven days from onset of symptoms. | 2020-12-09 |
| 33294111 | the COVID-19 pandemic, which results from infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), presents important diagnostic challenges. […] Diagnostic strategies available to identify or rule out current infection, or to identify people in need of care escalation, or to test for past infection and immune response have become available, to reduce household and community transmission. […] We highlight a Cochrane review, published in September 2020, on the assessment of diagnostic accuracy of point-of-care antigen and molecular-based tests to determine current SARS-CoV-2 infection. the authors of the Cochrane review searched multiple electronic databases for studies, which assessed SARS-CoV-2 infection with a diagnostic test. | 2020-12-09 |
| 33294160 | Due to the common failure in preoperative diagnosis, it is important for surgeons to have a clinical suspicion for de Garengeot herniae for patients, presenting with a right groin bulge. | 2020-12-09 |
| 33294487 | More policing about precautionary measures and ensuring diagnostic testing and accuracy are needed. | 2020-12-09 |
| 33294592 | The purpose of preparing this Feature Article was to explore and share my lived experience of living with multiple layers of chronic pain, with a diagnosis of advanced, aggressive and metastasized prostate cancer, and COVID-19. | 2020-12-09 |
| 33294596 | The main end points of this study were visit volume, wait times, visit duration, patient diagnosis, prescriptions received, and satisfaction. | 2020-12-09 |
| 33294847 | There is increasing evidence that these patients are at risk for various cardiovascular insults; however, there are currently no guidelines for the diagnosis and management of such cardiovascular complications in patients with coronavirus disease 2019. […] While there are guidelines for the diagnosis and management of pulmonary complications of coronavirus disease 2019, there needs to be more information regarding the management of cardiovascular complications as well. […] These recommendations garnered from the coronavirus disease 2019 cardiology subcommittee from our institution will add to the existing knowledge of these potential cardiovascular insults as well as highlight suggestions for the diagnosis and management of the range of cardiovascular complications of coronavirus disease 2019. | 2020-12-09 |
| 33294892 | Training should be implemented for all hospital staff on infection prevention techniques. | 2020-12-09 |
| 33294959 | Demographic data and principal electrocardiogram diagnosis were collected and analyzed. […] The comparative analysis of data shows a 54% reduction of telemedicine electrocardiogram transmission in Genoa telemedicine center (from 364 to 166), 68% in Brescia (from 5.745 to 1.905), 24% in Bari (from 15.825 to 11.716); relative reduction according to electrocardiogram diagnosis was 38% for acute coronary syndrome, 40% for other acute CVD in Genoa center, 24% for acute coronary syndrome, and 38% for other acute CVD in Bari. | 2020-12-09 |
| 33295064 | This platform will provide a more accurate and convenient pathway for diagnosis of COVID-19 or other infectious diseases in low-resource regions. | 2020-12-09 |
| 33295140 | Over the last 3 months, the pandemic has challenged the diagnosis and treatment of all cancer, including rectal cancer. | 2020-12-09 |
| 33295221 | Many organizations have recognized that COVID-19 patients may have sudden loss of smell or taste and have included these symptoms in their diagnostic guidelines. | 2020-12-09 |
| 33295313 | The Institute (IPK) was founded in 1937 and is now Cuba’s national reference center for the diagnosis, treatment, control and prevention of communicable diseases. | 2020-12-09 |
| 33295422 | The main described contributions of telemedicine in the diagnosis and treatment of such neurological conditions were presented, indicating a great potential of use of this type of assistance in all these fields. | 2020-12-09 |
| 33295423 | To describe two patients with severe SARS-CoV-2 infection and delayed recovery of consciousness after sedation withdrawal, in whom MRI disclosed multifocal white matter brain lesions, compatible with the diagnosis of acute disseminated encephalomyelitis. | 2020-12-09 |
| 33295610 | While much of the work remains in research laboratories, the first nano-based treatments, vaccines, drugs, and diagnostic devices, are now receiving approval for commercialisation and clinical use. | 2020-12-09 |
| 33295626 | These findings bolster confidence that reinforcement learning techniques can reliably guide resource allocation for future public health emergencies. | 2020-12-09 |
| 33295640 | Saliva represented a promising tool in COVID-19 diagnosis and the collection method would reduce the exposure risk of frontline health workers which is one of the major concerns in primary healthcare settings. | 2020-12-09 |
| 33295734 | COVID-19 which is the name given to the clinical syndrome related to this infection has been shown to own a wide diversity of clinical presentations which challenges the healthcare workers and makes difficult the diagnosis and management of patients. | 2020-12-09 |
| 33296088 | All adult virtual clinical encounters from March to May 2020 with a principal diagnosis of ARS were reviewed for demographic data and the presence or absence of an antibiotic prescription during the coronavirus shut down in Massachusetts. […] There were 2,075 patients in March to May 2020 and 3,654 patients March to May 2019 who received an ARS principal diagnosis at their virtual and in-person outpatient visits, respectively. | 2020-12-09 |
| 33296149 | Initial psychological responses were predictive of a PTSD diagnosis, even though most patients showing acute psychological distress (33.5% of the sample) improved in the following weeks. | 2020-12-09 |
| 33296169 | We also detail the recent development of diagnostic methods and potential treatment strategies of COVID-19 with focus on the ongoing clinical trials of antibodies, vaccines, and inhibitors for combating the emerging coronavirus. | 2020-12-09 |
| 33296477 | This was a descriptive cross-sectional study involving the total population of patients with laboratory confirmed diagnosis of COVID-19 in the University of Benin Teaching Hospital, Edo State, Nigeria from March 31 to June 30, 2020. | 2020-12-09 |
| 33296557 | The patients who have received rituximab treatment in the previous 5 years with the diagnosis of pemphigus group of diseases at Cerrahpaşa Medical Faculty were questioned for COVID-19 infection. | 2020-12-09 |
| 33296578 | There will also be high needs for all categories of healthcare workers and for both diagnostic and treatment equipment. | 2020-12-09 |
| 33296598 | The detection of trace protein biomarkers is essential in the diagnostic field. […] Despite continuous progress, current systems are insufficient for the diagnosis of diseases that require high sensitivity. | 2020-12-09 |
| 33296818 | After a mean of almost 50 days following the diagnosis, 98 patients (34.5%) reported clinically significant PTSD, anxiety, and/or depression, with PTSD being the most common condition reported (25.4%). | 2020-12-09 |
| 33297614 | Compared with the traditional prediction (i.e. using indicators from the first test at admission and the critical admission conditions to assess whether patients are in mild or severe status), the new model’s prediction additionally takes into account of the baseline physiological indicators and dynamic changes of COVID-19 patients, so it can predict the risk of severe outcomes in COVID-19 patients more comprehensively and accurately to reduce the missed diagnosis of severe COVID-19. | 2020-12-10 |
| 33297703 | CP is indicated mainly in severe cases of COVID-19, which require oxygen support, ideally within 2-3 days after diagnosis, but our and foreign experience shows a beneficial effect of CP even in moderately severe cases that do not need oxygen treatment. | 2020-12-10 |
| 33297938 | The fourfold elevation of NSE may have diagnostic/prognostic value as a biomarker in CSF for COVID-19 patients who have altered mental status. | 2020-12-10 |
| 33298131 | Due to the pandemic, 87.8% reported a decrease in the total number of patients undergoing emergency surgery and approximately 25% estimated a delay of more than 2 h in the time-to-diagnosis and another 2 h in the time-to-intervention. […] The combination of an estimated decrease in numbers of emergency surgical patients and an observed increase in more severe septic diseases may be a result of the fear of patients from infection with COVID-19 and a consecutive delayed hospital admission and diagnosis. […] A critical delay in time-to-diagnosis and time-to-intervention may be a result of changes in in-hospital logistics and operating room as well as intensive care capacities. | 2020-12-10 |
| 33298613 | With the approach of respiratory virus season in the Northern Hemisphere, clinical microbiology and public health laboratories will need rapid diagnostic assays to distinguish SARS-CoV-2 from influenza and respiratory syncytial virus (RSV) infections for diagnosis and surveillance. […] This test will provide a valuable clinical diagnostic and public health solution for detecting and differentiating SARS-CoV-2, influenza A and B, and RSV infections during the current respiratory virus season. | 2020-12-10 |
| 33298615 | We are presenting a highly specific diagnostic tool for the detection of SARS-CoV-2-reactive T cells. | 2020-12-10 |
| 33298746 | Levamisole is not currently included in routine drug testing panels, although a variety of confirmatory testing techniques exist across a range of antemortem and postmortem specimen options. | 2020-12-10 |
| 33298761 | Medical charts were reviewed for the date of admission, past medical history, and demographic variables, presenting signs and symptoms, admitting laboratory values, diagnostic imaging, diagnosis, treatment modalities, and outcomes including length of stay and disease severity. […] Approximately 2 weeks after the peak in reported SARS-CoV-2 cases in New Jersey, we began to see fewer pneumonia cases and an increase in admissions for Multi-Inflammatory Syndrome in Children and cases of acute appendicitis in association with a diagnosis of SARS-CoV-2 infection. | 2020-12-10 |
| 33298894 | Longitudinal characterization of SARS-CoV-2 PCR testing from COVID-19 patient’s nasopharynx and its juxtaposition with blood-based IgG-seroconversion diagnostic assays is critical to understanding SARS-CoV-2 infection durations. […] Here, we retrospectively analyze 851 SARS-CoV-2-positive patients with at least two positive PCR tests and find that 99 of these patients remain SARS-CoV-2-positive after 4 weeks from their initial diagnosis date. […] Among 104 patients with an IgG test result, 90 patients were seropositive to date, with mean upper bound of time to seropositivity from initial diagnosis being 37.8 days (95% CI: 34.3-41.3). | 2020-12-10 |
| 33299071 | Difficulty comprehending government advice and uncertainty of diagnosis, based on a public health policy of not testing to confirm self-reported COVID-19 infection during lockdown, therefore reduce willingness to adopt a government contact-tracing app to a level below the threshold for effectiveness as a tool to suppress an epidemic. | 2020-12-10 |
| 33299361 | In all presenting patients, initial symptoms showed large variation; therefore, COVID should be considered as a main differential diagnosis at every patient presentation, and patients with high pre-test probability should, if possible, be isolated until testing results are known. | 2020-12-10 |
| 33299720 | Central to these guidelines are preoperative COVID-19 testing, appropriate personal protective equipment, and operative techniques/principles that minimize operative time and aerosolization of the virus. | 2020-12-10 |
| 33299742 | Improved antibiotic stewardship can be accomplished through rapid diagnosis by longitudinal sampling of patients. | 2020-12-10 |
| 33299775 | This observational cohort study included Moroccan patients with COVID-19 diagnosis and were hospitalized in Cheikh Khalifa International University Hospital, Casablanca, Morocco between March 26 and April 20, 2020. | 2020-12-10 |
| 33299786 | COVID 19 so far is not a known cardiotropic virus, and the term “myocarditis” should be exclusively used after EMB or autopsy proven diagnosis. […] We describe the workup that led to the potential diagnosis. | 2020-12-10 |
| 33300117 | The role and performance of chest CT in the diagnosis of the coronavirus disease 2019 pandemic remains under active investigation. […] A recent case report in this journal found that a COVID-19 diagnosis has been made from the serological results despite first CT scan and RT-PCR negative results. | 2020-12-10 |
| 33300152 | Understanding the neuropathogenesis and cellular mechanisms underlying Neuro-SARS2 is crucial for both basic research and clinical practice to establish effective strategies for early detection/diagnosis, prevention, and treatment. | 2020-12-10 |
| 33300261 | The mean value of the FSFI satisfaction score differs from COVID-19 before and after diagnosis (P = .012). […] The score of the subgroups of FSFI did not differ from COVID-19 before and after diagnosis (P > .050). […] The median value of SF-36 pain differs from COVID-19 before and after diagnosis (P = .008). | 2020-12-10 |
| 33300355 | In this narrative review, our aim was to clarify the roles of diagnostic methods used in COVID-19 disease. […] The mainstay approach to limit this virus spread is an early and accurate diagnosis of the viral infection and appropriate quarantine of patients with coronavirus infection. […] In literature, there are numerous studies that underline the importance of CT as the first-step diagnostic tool in COVID-19 diagnosis. […] There is a need for an algorithm, which involves a combination of PCR and CT in diagnosis of COVID-19 (Ref. | 2020-12-10 |
| 33300378 | The majority of respondents were women (75%), 84% respondents were mentally healthy and did not have any diagnosis of mental illnesses. | 2020-12-10 |
| 33300700 | In connection with the scope and duration of the COVID-19 pandemic, the clinical judgement of clinicians and medical practitioners could be influenced such that diagnostic errors (delays and inaccuracies) may ensue. […] We hereby recall through two clinical scenarios the constant need for practitioners to take a step back in reflecting of the diagnostic process to avoid the « tunnel effect » which may result in delaying common and frequent infectious diseases. | 2020-12-10 |
| 33300956 | Among 16 570 patients diagnosed with COVID-19, 1200 had a cancer diagnosis and 690 had a recent cancer diagnosis of at least 1 of the 13 common cancers. […] Those with recent cancer diagnosis were at significantly increased risk for COVID-19 infection (aOR, 7.14 [95% CI, 6.91-7.39]; P < .001), with the strongest association for recently diagnosed leukemia (aOR, 12.16 [95% CI, 11.03-13.40]; P < .001), non-Hodgkin lymphoma (aOR, 8.54 [95% CI, 7.80-9.36]; P < .001), and lung cancer (aOR, 7.66 [95% CI, 7.07-8.29]; P < .001) and weakest for thyroid cancer (aOR, 3.10 [95% CI, 2.47-3.87]; P < .001). […] Among patients with recent cancer diagnosis, African Americans had a significantly higher risk for COVID-19 infection than White patients; this racial disparity was largest for breast cancer (aOR, 5.44 [95% CI, 4.69-6.31]; P < .001), followed by prostate cancer (aOR, 5.10 [95% CI, 4.34-5.98]; P < .001), colorectal cancer (aOR, 3.30 [95% CI, 2.55-4.26]; P < .001), and lung cancer (aOR, 2.53 [95% CI, 2.10-3.06]; P < .001). | 2020-12-10 |
| 33300996 | Computational linguistics and statistical techniques were applied to study the trend, content, and predictors of aging narratives. | 2020-12-10 |
| 33300998 | Only 128 (4%) people received a diagnosis of COVID-19, with a positive swab test. […] No flu vaccinations for the last five flu seasons were specifically associated with diagnosis of COVID-19 or with positive results of serology tests. | 2020-12-10 |
| 33301018 | Inpatient and hospital-based outpatient visits with a principal or secondary discharge diagnosis of COVID-19 (International Classification of Diseases, Tenth Revision, Clinical Modification diagnosis code, U07.1) between April 1 and May 31, 2020, were included. | 2020-12-10 |
| 33301073 | In light of the growing number of COVID-19 cases, the need for diagnostic tools to identify COVID-19 infection at early stages is of vital importance. | 2020-12-10 |
| 33301236 | Fibrin/fibrinogen degradation products (FDP) values reflect coagulation and fibrinolysis status, and FDP levels are helpful for diagnosis and classification of disseminated intravascular coagulation (DIC). […] LIASAUTO P-FDP displayed the reactivity towards various fibrin/fibrinogen degradation products, and it might be useful for DIC diagnosis because the fibrinolytic status differed in the DIC types and stages. | 2020-12-10 |
| 33301248 | Tracheostomy was performed using Ciaglia (22) and Griggs (9) techniques. | 2020-12-10 |
| 33301417 | Assigning meaningful probabilities of SARS-CoV-2 infection risk presents a diagnostic challenge across the continuum of care. […] The aim of this study was to develop and clinically validate an adaptable, personalized diagnostic model to assist clinicians in ruling in and ruling out COVID-19 in potential patients. […] We compared the diagnostic performance of probabilistic, graphical, and machine learning models against a previously published benchmark model. […] We trained models with 100,000 simulated patient profiles based on 13 symptoms and estimated local prevalence, imaging, and molecular diagnostic performance from published reports. […] Of these, 69% (n=38) were confirmed via reverse transcription-polymerase chain reaction (RT-PCR) to be positive for SARS-CoV-2 infection, and 20% (n=11) had repeated negative nucleic acid testing and an alternate diagnosis. […] After integrating imaging and laboratory test statistics with the predictions of the Bayesian inference network, changes in diagnostic uncertainty at each step in the simulated clinical evaluation process were highly sensitive to location, symptom, and diagnostic test choices. | 2020-12-10 |
| 33301459 | The risk of bias was assessed using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool. | 2020-12-10 |
| 33301657 | In comparative tests with similar test systems «Vitrotest® SARS-CoV-2 IgG» (Vitrotest, Ukraine) and «Anti-SARS-Cov-2 ELISA (IgG)» (EUROIMMUN AG, Germany) high diagnostic efficiency of the new test system was shown. | 2020-12-10 |
| 33301658 | The study presents the results of the creation and evaluation of the diagnostic characteristics of the rapid immunochromatographic test for the qualitative detection and differentiation of IgM/IgG antibodies to SARS-CoV-2 in human serum, plasma, and whole blood “ИХА-COVID-19-IgM / IgG”. […] Test kit can be use as the rapid diagnostic test in the context of the COVID-19 pandemic and to assess the immune status of convalescents. | 2020-12-10 |
| 33301883 | However, many of the reported cases do not completely fill the clinical diagnostic criteria, which has made some researchers use the term “Kawasaki-like disease” instead of KD for this state. | 2020-12-10 |
| 33301962 | Besides throat-nose swab polymerase chain reaction (PCR), unenhanced chest computed tomography (CT) is a recommended diagnostic tool for early detection and quantification of pulmonary changes in COVID-19 pneumonia caused by the novel corona virus. | 2020-12-10 |
| 33302235 | All signed diagnostic and procedural radiology reports were curated from January 1st to July 1st of 2019 and 2020. | 2020-12-10 |
| 33302632 | Thus, CT is an important clinical tool for early diagnosis and assessment of the severity of COVID-19. | 2020-12-11 |
| 33302684 | In the present study, we discuss the etiology, epidemiology, pathology, clinical manifestations, diagnosis, and treatment of SARS, MERS, and COVID-19 at first. | 2020-12-11 |
| 33302744 | Both techniques were well tolerated and most patients would repeat the procedure in hindsight. | 2020-12-11 |
| 33303102 | Guidance is provided with diagnostic “red flags” that raise the suspicion of pathology. | 2020-12-11 |
| 33303154 | The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. […] In fact, statistical reports of diagnostic tools show that their accuracy, specificity and sensitivity in the detection of COVID hampered by some challenges that can be eliminated by using nanoparticles (NPs). […] Afterward, some methods of COVID-19 detection such as imaging, laboratory and kit-based diagnostic tests are surveyed. […] Finally, current challenges and future perspective for the development of diagnostic or monitoring technologies in the control of COVID-19 are discussed to persuade the scientists in advancing their technologies beyond imagination. | 2020-12-11 |
| 33303174 | Targeting the total antibodies response to infection enabled achieving 100% diagnostic specificity (95.75-100, C.I. 95%, n = 85 healthy and with other infections individuals) and 94.6% sensitivity (84.9-98.9, C.I. 95%, n = 62 SARS CoV-2 infected subjects) as early as 7 days post confirmation of positivity. | 2020-12-11 |
| 33303323 | DNA-sensors based on DNA-modifying enzymes for fast determination and monitoring of pathogenic (Zika, Dengue, SARS-Cov-2 (inducer of COVID-19), human papillomavirus, HIV, etc.) viruses and diagnosis of virus-induced diseases is a key factor of this overview. […] Recently, DNA-modifying enzymes (Taq DNA polymerase, Phi29 DNA polymerase) have been widely used for the diagnosis of virus or pathogenic disease by gold standard (PCR, qPCR, RT-qPCR) methods, therefore, alternative methods have been reviewed. | 2020-12-11 |
| 33303510 | Endobronchial ultrasound (EBUS) has long been a common diagnostic tool used in the diagnosis of pulmonary pathologies. […] It improves the diagnostic yield of lesions and prevents subsequent referral to gastrointestinal colleagues which may delay diagnosis especially during the COVID-19 pandemic as was the case in our patient cohort where services are already limited. […] Each of our cases resulted in early histological diagnosis and subsequent appropriate treatment. | 2020-12-11 |
| 33303539 | In this prospective, multicentre, observational study, we systematically evaluated the cardiopulmonary damage in subjects recovering from COVID-19 at 60 and 100 days after confirmed diagnosis. […] A relevant percentage of post-COVID-19 patients presented with persisting symptoms and lung function impairment along with pulmonary abnormalities more than 100 days after the diagnosis of COVID-19. | 2020-12-11 |
| 33303562 | The determination of optimized cut-off values through ROC curves analyses had a significant impact on the diagnostic resolution of several enzyme immunoassays by increasing the sensitivity significantly without a large trade-off in specificity. | 2020-12-11 |
| 33303831 | We show that our workflow is effective at processing data from all recently proposed SARS-CoV-2 sequencing based diagnostic tests, and is generally applicable to any diagnostic HMSA. | 2020-12-11 |
| 33303951 | In a broader sense, BLI-ISA can be developed as a novel diagnostic platform to evaluate antibodies and other biomolecules in clinical specimens. | 2020-12-11 |
| 33304007 | The objective of this article is to share the strategy we used in order to restructure the radiology and diagnostic imaging department of a referral institution during the coronavirus disease 2019 pandemic, on the basis of the current recommendations. | 2020-12-11 |
| 33304008 | In this study we present ultrasound images of the lungs of neonates with a suspected or confirmed diagnosis of COVID-19, distinguishing between the changes related to COVID-19 and those unrelated to the disease. | 2020-12-11 |
| 33304207 | “Burn units”, “burns”, “COVID-19”, “health personnel”, “protective devices”, “severe acute respiratory syndrome coronavirus 2”, “surgeons” and “telemedicine” were reviewed during the entire diagnosis and management process of burn patients. | 2020-12-11 |
| 33304706 | We present a case of a 64-year-old female with past medical history of diabetes mellitus and hypertension who presented to the Emergency Medicine Department with shortness of breath and worsening chest discomfort, then had a ventricular fibrillation (VF) arrest while in triage, in the context of COVID-19 diagnosis. | 2020-12-11 |
| 33305162 | Since COVID-19 has caused numerous human casualties and severe economic loss posing a global threat, the development of readily available, accurate, fast, and cost-effective diagnostic techniques in hospitals and in any places where humans spread the virus is urgently required. […] These tests may include virus isolation, nucleic acid-based molecular assays like real-time polymerase chain reactions, antigen or antibody-based immunological assays such as rapid immunochromatographic tests, enzyme-linked immunosorbent assays, immunofluorescence techniques, and indirect fluorescent antibody techniques, electrochemical sensors, etc. […] However, current methods should be developed by novel approaches for sensitive, specific, and accurate diagnosis of COVID-19 cases to control and prevent this outbreak. […] Thus, this review will cover an overview and comparison of multiple reports and commercially available kits that include molecular tests, immunoassays, and sensor-based diagnostic methods for diagnosis of COVID-19. | 2020-12-11 |
| 33305456 | In the present study, we provide a brief review of the general biological features of CoVs and explain the pathogenesis, clinical symptoms and diagnostic approaches regarding monitoring future infectivity and prevent emerging COVID-19 infections. | 2020-12-11 |
| 33305475 | D-dimer values were recorded at diagnosis in children hospitalized for SARS-CoV-2-related manifestations. | 2020-12-11 |
| 33305544 | Using a large multi-center electronic health record network, we conducted a comparative cohort study of patients with SARDs diagnosed with COVID-19 (identified by diagnostic code or positive molecular test) versus non-SARD comparators with COVID-19, matched by age, sex, race/ethnicity, and body mass index (primary model) and comorbidities and health care utilization (extended model). | 2020-12-11 |
| 33305558 | He was identified on February 16, 2020, and his laboratory diagnosis was made on February 26, 2020. | 2020-12-11 |
| 33305712 | Therefore, understanding the cross-talk between lung and heart during COVID-19 might give us better clarity for early-diagnosis followed by appropriate treatment in patients with the likelihood of developing severe symptoms. | 2020-12-11 |
| 33305832 | The rapid spread of coronavirus disease 2019 (COVID-19), a disease caused by severe acute respiratory syndrome coronavirus 2, poses a huge demand for immediate diagnosis. […] Real-time reverse transcriptase-polymerase chain reaction (rRT-PCR) of nasopharyngeal (NP) and oropharyngeal (OP) swabs have been used to confirm the clinical diagnosis. | 2020-12-11 |
| 33305891 | We conducted a cross-sectional study starting on March 29 to April 5, 2020, based on a national online survey using snowball sampling techniques. | 2020-12-11 |
| 33305992 | Challenges include the diagnosis and identification of resistant infections, limited access to novel antimicrobials or to paediatric-friendly formulations, limited access to research and clinical trials and implementation challenges related to prevention and successful completion of treatment. | 2020-12-11 |
| 33306235 | All the patients had a confirmed COVID-19 diagnosis and no previously clinical record of autoimmune disease. | 2020-12-11 |
| 33306409 | Rapid SARS-CoV-2 diagnosis was soon perceived critical for arresting community spread and effective therapy development. | 2020-12-11 |
| 33306666 | Cardiac magnetic resonance imaging (CMR) with its new quantitative mapping techniques has proved to be an essential diagnostic tool for detecting myocardial injury associated with coronavirus disease 2019 (COVID-19) infection. […] Myocarditis (40.2%) was the most prevalent diagnosis. […] Myocarditis is the most common imaging diagnosis, with the common imaging findings being mapping abnormalities and myocardial edema on T2, followed by LGE. | 2020-12-11 |
| 33306735 | A cross-sectional clinical study was carried out, with a survey of all patients aged 0 to 17 years who were admitted with a diagnosis of respiratory diseases between January 2015 and July 2020. […] The variables used for analysis were date of admission, date of discharge, length of stay, age, sex and diagnosis. | 2020-12-11 |
| 33306764 | Nuclear medicine departments among others, have been reorganizing and reprioritizing diagnostic and theragnostic procedures. | 2020-12-11 |
| 33306976 | The CF dyes can be used along with existing flow cytometry dyes to provide a quick, accurate, and cost-effective method for the diagnosis and immunology treatment of diseases such as minimal residual disease (MRD) after cancer therapy. | 2020-12-11 |
| 33307062 | Sepsis is a leading cause of maternal death, and developing diagnostic tests for infection is increasingly important to reduce maternal mortality. […] The existing inflammatory markers, like C-reactive protein, are not specific for infection, which introduces diagnostic uncertainty. | 2020-12-11 |
| 33307163 | International and Canadian data have reported dramatically increased wait-times for diagnostic tests and cardiovascular procedures, as well as associated increased cardiovascular morbidity and mortality. […] Specific recommendations targeting the main pillars of cardiovascular care are presented: ambulatory, inpatient, procedural, diagnostic, surgical and rehabilitation. | 2020-12-11 |
| 33307227 | Molecular assays on nasopharyngeal swabs remain the cornerstone of COVID-19 diagnostic. […] This approach provides a valuable new option for COVID-19 diagnosis, only requiring a blood draw and easily scalable in all clinical laboratories. | 2020-12-11 |
| 33307658 | To assess the effectiveness of the use of low-frequency magnetotherapy in the complex medical rehabilitation of patients who have had pneumonia in the phase of convalescence. =22), therapy was carried out in accordance with the Temporary Clinical Recommendations of the Ministry of Health of the Russian Federation for the prevention, diagnosis and treatment of new coronavirus infection COVID-19 (version 8.1 of 01/10/2020), as well as the Temporary Clinical recommendations for medical rehabilitation for a new coronavirus infection (version 8.1 of 01/10/2020). | 2020-12-14 |
| 33308026 | Combining the assays detecting NC and S1/S2 antibody increased diagnostic yield. | 2020-12-14 |
| 33308161 | Telehealth was less suitable when a physical examination was needed, when the diagnosis was unknown or for patients who had a strong preference to be seen in-person. | 2020-12-14 |
| 33308254 | Developing therapeutic strategies for a SARS-CoV-2 infection is challenging, but first the correct diagnosis has to be made. […] However, early viral clearing jeopardizes a sound diagnosis of COVID-19. […] Computed tomography is a crucial diagnostic prerequisite in this context. | 2020-12-14 |
| 33308653 | Case finding, an important parameter in fight against Tuberculosis (TB) has always remained a challenge despite advances in diagnostic modalities, access to health care and administrative commitment. | 2020-12-14 |
| 33308658 | Since its outbreak, SARS-CoV-2 has had a major impact on clinical diagnostic laboratories. […] At present, there is a growing list of over 400 SARC-CoV-2 diagnostic tests either in development or approved for clinical use. […] Proper respiratory specimen collected at the appropriate time and from the right anatomical site is critical in the accurate and timely diagnosis of SARSCoV2. […] Real-time RT-PCR based molecular assay remains the test of choice for the etiological diagnosis of SARS-CoV-2 while serological tests are being introduced as supplementary tools. […] Finally, there is an urgent need for scaling up the diagnostic capacity by the introduction of reliable and accurate point-of-care tests which will assist in effective control of this outbreak. | 2020-12-14 |
| 33308662 | The consequences of the COVID-19 pandemic, and our global response to it with lockdowns, are likely to leave a profound and long-lasting impact on TB diagnosis and control, potentially leading to an additional 6.3 million cases of TB between 2020 and 2025, and an additional 1.4 million TB deaths during this time. | 2020-12-14 |
| 33308664 | Accurate and rapid diagnostic tests are critical for achieving control of coronavirus disease 2019 (covid-19), a pandemic illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Diagnostic tests for covid-19 fall into two main categories: molecular tests that detect viral RNA, and serological tests that detect anti-SARS-CoV-2 immunoglobulins. […] Reverse transcriptase polymerase chain reaction (RT-PCR), a molecular test, has become the gold standard for diagnosis of covid-19; however, this test has many limitations that include potential false negative results, changes in diagnostic accuracy over the disease course, and precarious availability of test materials. […] Serological tests have generated substantial interest as an alternative or complement to RT-PCR and other Nucleic acid tests in the diagnosis of acute infection, as some might be cheaper and easier to implement at the point of care. | 2020-12-14 |
| 33308845 | The aim of the study is to know the prevalence of SARS-CoV-2 infection in patients and professional staff of a medium or long-stay hospital during the peak period of the pandemic in Spain, spring 2020. , 2020. 26 out of 230 patients tested positive in any of the diagnostic techniques (PCR, antibodies IgG, IgM) with a 11.30% prevalence. […] 5.95% in outpatients, with a significantly higher risk in admitted patients after adjustment for age and gender (OR=3,309, 95%CI: 1,154-9,495). 24 out of 294 hospital staff tested positive in any of the diagnostic techniques, with a 8.16% prevalence. […] Combining PCR tests (gold standard) with antibodies tests proved useful as a diagnostic strategy. | 2020-12-14 |
| 33308853 | The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. | 2020-12-14 |
| 33308865 | Women with a current or prior diagnosis of ovarian cancer completed an online survey which included a query about coping strategies during the COVID-19 pandemic. | 2020-12-14 |
| 33308974 | With these new initiatives, it is conceivable that the diagnosis of cancer care may be delayed. […] We performed a retrospective review of our electronic medical record and examined patient characteristics of those presenting for a possible new cancer diagnosis to our urologic oncology clinic. | 2020-12-14 |
| 33309464 | All regression models included age, gender, ethnicity, diagnosis of psychiatric condition, level of education, being at high-risk for difficulties relating to COVID-19, living alone, and diagnosed or suspected COVID-19 as covariates. | 2020-12-14 |
| 33309506 | In this study, we aimed to investigate and compare the prognostic impacts of C-reactive protein (CRP), white blood cell (WBC) count, neutrophil (NEU)-to-lymphocyte (LYM) ratio (NLR), platelet-to-lymphocyte ratio (PLR), Red Cell Distribution Width (RDW) biomarkers in laboratory-confirmed COVID-19 cases as well as to explore the most useful diagnostic biomarkers and optimal cutoff values in COVID-19 patients. | 2020-12-14 |
| 33309535 | COVID-19 outcomes varied significantly among Californians receiving IDD services by type of residence and skilled nursing care needs: higher rates of diagnosis in settings with larger number of residents, higher case-fatality and mortality rates in settings that provided 24-h skilled nursing care. […] Diagnosis with COVID-19 among Californians receiving IDD services appears to be related to the number of individuals within the residence, while adverse COVID-19 outcomes were associated with level of skilled nursing care. | 2020-12-14 |
| 33309764 | In this population-based study in the Veneto Region, we retrospectively reviewed all patients aged 65 years or older, with a laboratory-confirmed COVID-19 diagnosis. | 2020-12-14 |
| 33309899 | For screening procedure delay, outcomes included 5-year survival and cancer stage at diagnosis. | 2020-12-14 |
| 33310108 | Overall diagnostic sensitivities were: Euroimmun (IgA) 87%; Epitope Diagnostics (IgG) 83%; YHLO (IgG) 77%; Roche (IgM/IgG) 77%; Euroimmun (IgG) 75%; Diasorin (IgG) 53%; Epitope Diagnostics (IgM) 52%; Snibe (IgG) 47%; YHLO (IgM) 35%; and Snibe (IgM) 26%. […] Diagnostic specificities were: YHLO (IgG) 100%; Roche, 100%; Snibe (IgM/IgG) 100%; Diasorin (IgG) 97%; Euroimmun (IgG) 94%; YHLO (IgM) 94%; Euroimmun (IgA) 83%. | 2020-12-14 |
| 33310113 | Polysomnography (PSG) examinations are essential for the diagnosis and treatment management of several sleep disorders, which may constitute a public or personal safety issue such as obstructive sleep apnea syndrome. | 2020-12-14 |
| 33310595 | We retrospectively identified patients in the Vizient Clinical Data Base® with IS as a discharge diagnosis. | 2020-12-14 |
| 33310656 | Among asymptomatic women, 16 /103 (15 %) became symptomatic after diagnosis. | 2020-12-14 |
| 33310733 | CRISPR-read SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) RNA levels were similar in patient saliva and nasal swabs, and viral loads measured by RT-PCR and the smartphone-read CRISPR assay demonstrated good correlation, supporting the potential use of this portable assay for saliva-based point-of-care COVID-19 diagnosis. | 2020-12-14 |
| 33310830 | We briefly review the pathophysiology and diagnosis of TCM (also described as apical ballooning syndrome and stress-induced cardiomyopathy). […] Additionally, this case highlights the importance of a multidisciplinary approach to clinical decision-making and resource allocation in diagnosis and management of critical illness in the setting of the ongoing international COVID-19 pandemic. | 2020-12-14 |
| 33311861 | Secondly, the results of two forecasting approaches in the SSA, namely vector and recurrent forecasting, are compared to those from other commonly used time series forecasting techniques. | 2020-12-14 |
| 33312022 | In this study, it is aimed to review the studies on newborn babies with COVID-19 infection and to compile the epidemic data, clinical findings, diagnosis and current information recommended for treatment. | 2020-12-14 |
| 33312067 | We included all consecutive patients who were admitted in Cheikh Khalifa International University Hospital, Casablanca, Morocco, between February to April 2020, with a confirmed diagnosis of COVID-19 infection using SARS-CoV-2 viral nucleic acid via RT-PCR. | 2020-12-14 |
| 33312178 | As a whole, we propose that a high MAFB/MAF expression ratio in lung macrophages could serve as an accurate diagnostic tool for COVID-19 progression. | 2020-12-14 |
| 33312565 | These observations provide a timely monitoring approach for identifying SARS-CoV-2 cellular immunity and may serve as a diagnostic for the stratification of risk in immunocompromised and other at-risk individuals. | 2020-12-14 |
| 33312763 | As clinician-scientists delivering mind-body interventions in our hospital, we suggest applying evidence-based mind-body techniques that promote resiliency and adaptive coping during these difficult times. | 2020-12-14 |
| 33312843 | Patients who have experienced a systemic allergic reaction following an insect sting should be referred to an allergy specialist for diagnosis and treatment. | 2020-12-14 |
| 33312852 | In all cases, the underlying conditions, clinical presentation, fungal diagnostic tests used and their results, features of the chest scan images, antifungals used and clinical outcomes are detailed. | 2020-12-14 |
| 33312997 | Drug-induced first-degree AVB from paliperidone and mirtazapine should be on the differential diagnosis in patients on paliperidone and/or mirtazapine who present with chest pain, tachycardia or new-onset first-degree AVB. | 2020-12-14 |
| 33313015 | An appropriate epidemiological approach and differential diagnosis are very important so that the right clinical intervention can be selected. | 2020-12-14 |
| 33313016 | These manifestations have a broad differential diagnosis and it was difficult to exclude drug reactions. […] We hope to raise awareness of this possible manifestation of COVID-19 in order to raise suspicion of this diagnosis among clinicians when they encounter patients with fever and rash. […] Cutaneous manifestations can occur as part of COVID-19, so clinicians should be suspicious of this diagnosis in patients with fever and rash.The differential diagnosis is large and drug reactions are difficult to rule out. | 2020-12-14 |
| 33313018 | Her Epstein-Barr virus serology was positive and thus the diagnosis was infectious mononucleosis. | 2020-12-14 |
| 33313569 | Rapid antibody test could help in diagnosis of COVID-19 in asymptomatic or symptomatic EMS personnel who did not undergo RT-PCR test or the test was reported as negative. […] However, its sensitivity could be enhanced through use along with other diagnostic methods. | 2020-12-14 |
| 33313582 | This study aimed to compile the up-to-date information about the methods and pharmacological agents used in the diagnosis and treatment of coronavirus disease 2019 (COVID-19) and examine the methods used in the treatment of COVID-19 in patients in the intensive care unit by reviewing the treatment guidelines published by national health authorities worldwide. | 2020-12-14 |
| 33313973 | As consequence, we underline that measures to guarantee oncogenetic testing (e.g., gBRCA testing) along with new diagnostic/clinic strategies are mandatory. | 2020-12-14 |
| 33314116 | These risks are not confined to those with a pre-existing dysautonomia diagnosis. | 2020-12-14 |
| 33314316 | Lymphocyte count (LYM) of peripheral blood and some indices of general biochemical analysis had diagnostic and prognostic value for coronavirus disease 2019 (COVID-19), and the value of other remaining indices is rare. […] The diagnostic and prognostic value of indices in peripheral blood cell count and general biochemical analysis was analyzed. […] Neutrophil/lymphocyte ratio (NLR) had higher sensitivity and specificity for COVID-19 diagnosis. | 2020-12-14 |
| 33314322 | Data were analysed for the period February to September 2020, with the number of services provided per month across five categories (diagnostic, preventive, restorative, endodontic and oral surgery) compared with the monthly average for 2019 (95% CI) and the same month for 2019. […] There was a greater decline in preventive and diagnostic services, and a smaller decline in endodontic and oral surgery services. | 2020-12-14 |
| 33314910 | Telemedicine or mobile health (mHealth) is well-positioned during this time to reduce potential disease spread and prevent overloading of the healthcare system through at-home COVID-19 screening, diagnosis, and monitoring. | 2020-12-14 |
| 33315008 | This has resulted in an urgent need to obtain information regarding its pathogenesis, diagnosis and clinical manifestations. […] They may help establishing an early diagnosis, namely in oligosymptomatic patients or when confirmatory tests are impossible to perform. | 2020-12-14 |
| 33315115 | Time-to-treatment initiation (TTI), the interval between diagnosis and therapy, using intervals of 8 to 60, 61 to 120, 121 to 180, and greater than 180 days. 5-year and 10-year predicted all-cause mortality. | 2020-12-14 |
| 33315119 | The present case describes the diagnostic and therapy of the pulmorenal syndrome of a 40-year-old patient who presented in our clinic due to increasing respiratory insufficiency and hemoptysis with confirmed COVID-19 disease. | 2020-12-14 |
| 33315138 | Except for one participant with a pre-existing diagnosis of rheumatoid arthritis, all other participants were previously healthy. | 2020-12-14 |
| 33315163 | Weeks passed before the diagnosis was established. | 2020-12-14 |
| 33315348 | 65 years who were hospitalized with the diagnosis of new coronavirus pneumonia (COVID-19). | 2020-12-14 |
| 33315725 | The role of teleglaucoma has expanded and will continue to evolve as remote diagnostic devices undergo further refinement and validation. | 2020-12-14 |
| 33315728 | Lung cancer scans for initial diagnosis/staging saw the largest fall and slowest recovery compared with scans for known lung cancer. | 2020-12-14 |
| 33315854 | In addition, it suggests that CLOCC can be considered as a differential diagnosis by clinicians in patients with SARS-CoV-2 infection who present with unexplained neurological and neuropsychiatric symptoms, leading to poor outcome. | 2020-12-14 |
| 33316056 | We describe the pathology in three patients with severe COVID-19 who underwent antemortem examination of lung tissue at least 8 weeks after initial diagnosis. | 2020-12-14 |
| 33316059 | In addition, for SARS-CoV-2 detection, specimens are usually shipped to a designated laboratory for testing, which may extend the diagnosis and treatment time of patients with COVID-19. | 2020-12-14 |
| 33316070 | A total of 51 patients were included in the study (46 women, mean age at diagnosis of infection of 60 years). | 2020-12-14 |
| 33316223 | A face-to-face consultation was avoided for at least 3 months in 85% of patients (n=318); 87.1% (n=325) received a diagnosis and the dermatologist’s level of confidence in this diagnosis was 7 or higher in 77.5% of cases (n=290). | 2020-12-14 |
| 33316254 | In this retrospective study, patients found to have a CTPA and a COVID-19 diagnosis during the same admission were selected for analysis. | 2020-12-14 |
| 33316285 | The worldwide COVID-19 pandemic outburst has caused a serious public health issue with increasing needs of accurate and rapid diagnostic and screening testing. | 2020-12-14 |
| 33316401 | Treatment with azithromycin for ≥3 days was associated with the diagnosis of probable IPA (odds ratio 3.1, 95% confidence interval 1.1-8.5, p = 0.02). | 2020-12-14 |
| 33316596 | In this study, the first attempted COVID-19 case predicting model based on county-level demographic, environmental, and mobility data was constructed with multiple machine learning techniques and a hybrid framework. […] In future works, we expect to involve a longer period of data, consider more county-dependent factors, and employ more sophisticated techniques to decrease the modeling uncertainty and apply it to counties nationally and other countries. | 2020-12-14 |
| 33317101 | The diagnosis is established similar to other etiologies, and is based on detailed history, clinical exam, laboratory findings and non-invasive imaging studies. […] Endomyocardial biopsy may be performed if the diagnosis remains uncertain. | 2020-12-15 |
| 33317135 | We used the DSM-5 diagnostic guidelines to categorize participants as fulfilling the PTSD symptom criteria or not. | 2020-12-15 |
| 33317461 | One hundred eligible patients with diagnosis of COVID-19 were recruited in the study and assigned randomly to two groups of either hydroxychloroquine followed by KALETRA (Lopinavir/ritonavir) or hydroxychloroquine followed by ARB. | 2020-12-15 |
| 33317538 | The focus is on well known, pathogenic viruses for which there are ample diagnostic tools. | 2020-12-15 |
| 33317566 | Regarding his treatment, since there was no recommended replacement to heparin available to us at the time of diagnosis, we decided to use rivaroxaban temporarily. | 2020-12-15 |
| 33317745 | Finally, we further summarized the significance of the neuroinvasion and the follow-up issues that need to be paid attention to by scientists, so as to help neurologists understand the influence of SARS-CoV-2 on nervous system better and promote the accurate diagnosis and efficient treatment of COVID-19. | 2020-12-15 |
| 33318065 | Multiple serologic tests have been developed for SARS-CoV-2. […] Highly sensitive and specific immunological diagnostic methods for antibodies or those that directly detect viral antigens in clinical samples would be beneficial for the rapid and accurate diagnosis of SARS-CoV-2 infection. | 2020-12-15 |
| 33318316 | COVID-19 was diagnosed according to the COVID-19 diagnosis and treatment plan released by the National Health and Health Committee of China. | 2020-12-15 |
| 33318528 | We coupled these data with symptom reports and COVID-19 diagnosis data. | 2020-12-15 |
| 33318594 | Immunohistochemistry and in situ hybridisation techniques that facilitate reliable and reproducible detection of SARS-CoV and SARS-CoV-2 viral products in formalin-fixed paraffin-embedded (FFPE) specimens would be of great utility. […] The diverse techniques for virus detection and control material generation demonstrated in this study can be applied to investigations of coronavirus pathogenesis and therapeutic research in animal models. | 2020-12-15 |
| 33318646 | However, there are several challenges associated with the diagnostic of the COVID-19 during the current outbreak (Liu and Li (2019), Nature 2020;579:265-9, N. […] Firstly, the high number of cases overwhelms diagnostic test capacity and proposes the need for a rapid solution for sample processing (Science 2018;360:444-8). […] Molecular biology tools that include gene-editing approaches such as CRISPR-Cas12/13-based SHERLOCK, DETECTR, CARVER and PAC-MAN, antisense oligonucleotides, antisense peptide nucleic acids, ribozymes, aptamers, and RNAi silencing approaches produced with cutting-edge scientific advances compared to conventional diagnostic or treatment methods could be vital in COVID-19 and other future outbreaks. […] Thus, in this review, we will discuss potent the molecular biology approaches that can revolutionize diagnostic of viral infections and therapies to fight COVID-19 in a highly specific, stable, and efficient way. | 2020-12-15 |
| 33318711 | We aim to correlate those patients’ demographics, symptoms and comorbidities, with the risk of mortality from COVID-19, length of hospital stay, and time from diagnosis to definitive outcome. […] Moreover, a multivariable linear regression conducted with statistically significant variables (p < 0.05) showed that age (OR = 0.97, 95% CI = 0.95-0.98, p < 0.001) and time from diagnosis to definitive outcome (OR = 1.67, 95% CI = 1.64-1.71, p < 0.001) are associated with the length of hospital stay. | 2020-12-15 |
| 33318719 | As data collection techniques, students were asked to write learning log diaries and reflective essays and to participate in an online focus group discussion. | 2020-12-15 |
| 33318723 | We argue that the integration of these techniques into local, national, and international healthcare systems will save lives, and propose specific methods by which implementation can happen swiftly and efficiently. […] We offer to extend these resources and knowledge to assist policymakers seeking to implement these techniques. | 2020-12-15 |
| 33318752 | In this focused review, the authors discuss how COVID-19 is affecting acute cardiology care and propose pragmatic guideline modifications for the diagnosis and management of acute coronary syndrome patients, particularly around the appropriateness of invasive strategies as well as length of hospital stay. | 2020-12-15 |
| 33318859 | Finally, as a major warning for targeted techniques, a loss of coverage in any given region of the genome should alert to a potential rearrangement or a SNP in primer-annealing or probe-hybridizing regions and would require further validation using unbiased metagenomic sequencing. | 2020-12-15 |
| 33318893 | We used the techniques of Laplace Adomian decomposition method for the approximate solution of consider system. | 2020-12-15 |
| 33318916 | •Geographic Information System (GIS) techniques are widely used across scientific disciplines, including public health since the mid-1960s. | 2020-12-15 |
| 33319345 | It guided the diagnosis in cases where CT was non-contributory and led to a change in therapeutic management in most patients. | 2020-12-15 |
| 33319383 | Rapid and accurate diagnosis of 2019-nCoV are important for early treatment and cutting off epidemic transmission. […] In this review, recent advances in nano-based techniques have been highlighted and compared briefly with PCR and CT as well-known methods for 2019-nCoV detection. | 2020-12-15 |
| 33319449 | We address the impact of COVID-19 on organ transplantation globally and review current understanding of the epidemiology, outcomes, diagnosis and treatment of COVID-19 in SOT recipients. | 2020-12-15 |
| 33320080 | Bacterial and fungal co-infections caused by region-endemic pathogens, including hypervirulent K. pneumoniae in eastern Asia, should be included in the differential diagnosis of coronavirus disease patients with acutely deteriorating condition. | 2020-12-15 |
| 33320294 | The COVID-19 pandemic has a major impact on the diagnosis and treatment of ENT patients. […] Especially worrisome was that diagnostic procedures for suspected malignancies decreased by 41% during the pandemic. | 2020-12-15 |
| 33320635 | human tissue models, for more efficient diagnosis, drug/vaccine development, and focusing on the need for patient-specific therapy. […] We believe that combining the basics of virology with tissue engineering techniques can help the researchers to understand the molecular mechanism underlying viral infection, which is critical for effective drug design. | 2020-12-15 |
| 33320717 | The elderly immunocompromised patients with pre-existing comorbidities being more risk-prone to severe COVID-19, the importance of early diagnosis and intervention in AKI is imperative. | 2020-12-15 |
| 33320822 | The main objective of this research study was to determine the effectiveness of delivering an EI curriculum and mindfulness techniques using an AI conversation platform, Ajivar, to improve symptoms of anxiety and depression during this pandemic. | 2020-12-15 |
| 33320825 | An analysis of self-reported COVID-19 symptom items revealed a 1-factor solution, the EPICOVID19 diagnostic scale. […] We developed a short diagnostic scale to detect subjects with symptoms that were potentially associated with COVID-19 from a wide population. […] Although these results come from the Italian pandemic period, this short diagnostic scale could be optimized and tested as a screening tool for future similar pandemics. | 2020-12-15 |
| 33320856 | With the ongoing COVID-19 (Coronavirus Disease 2019) pandemic, caused by the novel coronavirus SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), there is a need for sensitive, specific, and affordable diagnostic tests to identify infected individuals, not all of whom are symptomatic. | 2020-12-15 |
| 33320883 | The recent outbreak of betacoronavirus Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which is responsible for the Coronavirus Disease 2019 (COVID-19) global pandemic, has created great challenges in viral diagnosis. […] Thus, there is an urgent demand to develop a rapid, inexpensive, and sensitive diagnostic test to aid point-of-care viral detection for disease monitoring. […] In this study, we developed a clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR associated proteins (Cas) 12a-based diagnostic method that allows the results to be visualized by the naked eye. | 2020-12-15 |
| 33321139 | We then review the literature on the pharmaceutical stability of mRNA vaccine candidates, including attempts to improve their stability, analytical techniques to monitor their stability, and regulatory guidelines covering product characterization and storage stability. | 2020-12-15 |
| 33321326 | Majority of the AIDP (66.7%) and AMAN/AMSAN (57.2%) patients belonged to Brighton level 1 indicating maximum diagnostic certainty. | 2020-12-15 |
| 33321459 | This study aimed to investigate the incidence, computed tomography (CT) characteristics, and diagnostic value of the VE pattern in coronavirus disease 2019 (COVID-19). […] A good understanding of the CT characteristics of the VE pattern may contribute to the early and accurate diagnosis of COVID-19 and prediction of the evolution of lesions. | 2020-12-15 |
| 33322035 | As a result that these tests cannot be done in local clinics where RT-qPCR testing capability is lacking, rapid antigen tests (RATs) for COVID-19 based on lateral flow immunoassays are used for rapid diagnosis. | 2020-12-16 |
| 33322959 | The diagnosis of COVID-19 was based on the results of real-time reverse-transcriptase polymerase-chain-reaction (rRT-PCR) detection. | 2020-12-16 |
| 33323137 | The NPV of this strategy was calculated for (1) clinical coronavirus disease 2019 (COVID-19) diagnosis from day 8-14 after exposure, and for (2) asymptomatic SARS-CoV-2 detected by standardized nasopharyngeal swab and saliva specimens collected at days 9, 10, and 14 after exposure. | 2020-12-16 |
| 33323339 | The diagnosis of childhood absence epilepsy (CAE) is typically based on history and description of spells, supported by an office-based positive hyperventilation test and confirmed by routine electroencephalography (EEG). […] Our series documents the feasibility of CAE diagnosis and management by telemedicine. | 2020-12-16 |
| 33323794 | Psychiatry’s patients have lost a past of community-based mental health services, interdisciplinary care teams, preventive consultation with social agencies, and, with reimbursements targeted for 15-minute visits, time adequate with the physician to individualize diagnosis and treatment. | 2020-12-16 |
| 33323917 | CASE REPORT A 61-year-old man presented with a painful, swollen limb and gangrene, findings consistent with a diagnosis of PCD due to venous thrombosis. | 2020-12-16 |
| 33323921 | In the specific case of cystic fibrosis detection, the implementation of a new strategy meant a 100% reduction in the request for second samples and a 70% reduction in the age of diagnosis of the newborn. | 2020-12-16 |
| 33323923 | The purpose of this paper was to describe the diagnosis, treatment and follow-up of patients diagnosed with congenital hypothyroidism (CH) by the Neonatal Screening Program in the Autonomous Community of Madrid during the state of alarm due to the COVID-19 health crisis. […] The data were extracted from the retrospective analysis of patients diagnosed with CH and treated at the Clinical Diagnosis and Follow-up Center of CH located in the Pediatric Endocrinology Unit of the General University Hospital Gregorio Marañon. […] The Screening Center contacted the Clinical Diagnosis and Follow-up Center urgently, with the location and clinical assessment of the patient on the same day, performing the usual complementary examinations in all of them according to clinical pathway. […] The median age of diagnosis was 15.5 days (range 7.00-24.00). […] All patients seen at the Congenital Hypothyroidism Clinical Diagnosis and Follow-up Center during the alarm state period were diagnosed, treated and reevaluated following the usual clinical pathways without incidents. | 2020-12-16 |
| 33324131 | Patients did not dare to go to their general practitioner, general practitioners were reticent about hospital referrals, and diagnostic and treatment trajectories were delayed or adapted. […] From the week of the first COVID-19 diagnosis in the Netherlands, a decrease of 20-40% in the number of cancer diagnosis was noticed. […] This decrease was observed in nearly all cancer types, including cancers such as lung cancer (average 23%), head-neck cancer (average 36%) and hematology (average 26%), for which a missed or delayed diagnosis can be life threatening. | 2020-12-16 |
| 33324324 | Non-invasive neuromodulation is a toolbox of techniques that based on targeted pathways and empirical evidence (largely in non-COVID-19 patients) can be investigated in the management of patients with COVID-19. | 2020-12-16 |
| 33324525 | The diagnosis was confirmed by real-time polymerase chain reaction (RT-PCR) and computed tomography (CT) imaging of the lungs. | 2020-12-16 |
| 33324948 | We reviewed the charts of all patients who had telehealth visits from April 1 through April 30, 2020, and collected demographic information, diagnosis, type of visit, and whether they received surgery; a satisfaction questionnaire was also administered. | 2020-12-16 |
| 33325043 | Highly scored recommendations included definition of urgent/emergent cases that required surgery; surgery for acute airway obstruction; prompt diagnosis of suspected cancer; and surgical intervention for sepsis following initial first-line medical management. | 2020-12-16 |
| 33325240 | The primary outcome was death within 28 days of COVID-19 diagnosis. […] Secondary outcomes were COVID-19 diagnosis and COVID-19-related hospital admission. […] There was no association between BP control and COVID-19 diagnosis or hospitalization. | 2020-12-16 |
| 33325426 | This paper describes an ultrasonographic diagnosis of a foot ganglion - after sewing 300 face masks within two months using a foot-operated sewing machine. | 2020-12-16 |
| 33325715 | Shotgun proteomics techniques infer the presence and quantity of proteins using peptide proxies produced by cleavage of the proteome with a protease. | 2020-12-16 |
| 33326307 | This article draws on the experience of the China NMPA in evaluating diagnostic reagents used to supplement the gold standard test method in the early stage of an epidemic of an infectious disease, as well as to serve as reference for clinicians and regulators. | 2020-12-16 |
| 33326377 | Most of existing methods can be summarized as anomaly object detection-based and reconstruction error-based techniques. | 2020-12-16 |
| 33326405 | The objective of this study was to conduct a systematic review of the literature on the role of AI as a comprehensive and decisive technology to fight the COVID-19 crisis in the fields of epidemiology, diagnosis, and disease progression. […] These publications were classified into 3 themes based on AI applications employed to combat the COVID-19 crisis: Computational Epidemiology, Early Detection and Diagnosis, and Disease Progression. […] Next, 40 of 130 (30.8%) studies that applied AI techniques to detect COVID-19 by using patients’ radiological images or laboratory test results were classified under the Early Detection and Diagnosis theme. | 2020-12-16 |
| 33326409 | Telehealth has the potential to increase treatment availability, decrease diagnosis waiting times, and aid in NDD monitoring. | 2020-12-16 |
| 33326503 | We conducted a diagnostic accuracy study where subjects with a confirmed diagnosis of COVID-19 (n = 401) and healthy volunteers (n = 100) were asked to self-swab from their oropharynx and mid-turbinate (OPMT), and self-collect saliva. | 2020-12-16 |
| 33326873 | To develop a novel quadruplex real-time reverse transcription polymerase chain reaction (rRT-PCR) assay for the diagnosis of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, differential diagnosis and detection of co-infections. | 2020-12-16 |
| 33326924 | Future work in pandemic simulations should use empirical human activity data for agent-based techniques. | 2020-12-16 |
| 33327890 | Inclusion criteria were diagnosis of oncologic disease, COVID-19-related symptoms, and signed written informed consent. | 2020-12-17 |
| 33327924 | Currently, RNA RT-PCR is the screening tool, while bilateral chest CT is the confirmatory clinical diagnostic test. […] This review article summarizes current data on the COVID-19 pandemic starting from the early outbreak, viral structure and origin, pathogenesis, diagnosis, treatment, discharge criteria, and future research. | 2020-12-17 |
| 33328150 | Retrospective descriptive study of children with confirmed or probable diagnosis of COVID-19 attended by telephone consultations in Hospital La Paz (Madrid) between March and June 2020. […] COVID-19 diagnosis was confirmed in 33 children by RT-PCR, and in 7 by serology tests. | 2020-12-17 |
| 33328211 | A Diagnostic and Statistical Manual of Mental Disorders fifth edition diagnosis of brief psychotic disorder with marked stressor (brief reactive psychosis) was made. | 2020-12-17 |
| 33328406 | For this reason, PILS should be considered in the differential diagnosis post-COVID-19 patients. | 2020-12-17 |
| 33328754 | To explore the clinical value of SARS-CoV2 IgM and IgG antibodies in the diagnosis of COVID-19 in suspected cases by likelihood ratio. […] By reinterpreting data from a previous study, the positive likelihood ratio of IgM and IgG antibodies in COVID-19 pneumonia diagnosis was calculated, and the posterior probability of IgM and IgG antibodies and their tandem detection was calculated finally. […] However, the posterior probability of the two antibody-tandem test was 99.15%, which could give clinicians more quantitative confidence in the diagnosis of COVID-19 in suspected cases. | 2020-12-17 |
| 33329044 | This study provides significant findings that will be used not only to supplement previous studies carried out in Morocco in order to resume the epidemiological situation in comparison with other countries, but also to improve the quality of the diagnosis of COVID-19 patients by identifying all the symptoms of the disease and better understanding its clinical outcomes. | 2020-12-17 |
| 33329136 | The findings suggest that singles and those with a psychiatric diagnosis were most affected by loneliness during the implementation of social distancing measures to impede the coronavirus. | 2020-12-17 |
| 33329152 | A large number of patients with neurocognitive disorders missed crucial appointments due to government’s restrictive measures, and many experienced a delay in initial diagnosis and initiation of treatment. | 2020-12-17 |
| 33329335 | Presently the early recognition and diagnosis of neurological manifestations remains a challenge for clinicians as the SARS-CoV-2 related neurological manifestations are in evolution. | 2020-12-17 |
| 33329336 | However, one of the crucial steps in neuromuscular diseases is diagnosis, and in most scenarios, more than one face-to-face visit is needed. | 2020-12-17 |
| 33329592 | Laboratory results within 24 h after the diagnosis of sepsis were provided by the clinical laboratory. | 2020-12-17 |
| 33329607 | Moreover, it is possible that mucosal immunity can be exploited for beneficial diagnostic, therapeutic, or prophylactic purposes. | 2020-12-17 |
| 33329662 | Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. […] Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. | 2020-12-17 |
| 33329895 | Chest computed tomographic scanning is helpful for diagnosis. | 2020-12-17 |
| 33329934 | The nuclear medicine field holds accurate and safe exam techniques, such as positron emission tomography-computed tomography and scintigraphy, that allow the anatomophysiological study of the majority of human organ systems. | 2020-12-17 |
| 33329953 | Under diagnosis and treatment of mental health illnesses lead to chronic presentations and consequences. | 2020-12-17 |
| 33329994 | Health Care Worker are faced with the uncertainty of contracting infections while performing procedures in patients with a confirmed diagnosis of COVID-19 or suspected cases. | 2020-12-17 |
| 33330119 | To develop a rapid detection reagent for SARS-CoV-2 antigen for the auxiliary diagnosis of new coronary pneumonia (COVID-19), and perform the methodological evaluation and clinical evaluation of the reagent. | 2020-12-17 |
| 33330317 | Aim of this manuscript is to provide a guidance model for the management of suspected, probable, or confirmed cases of SARS-CoV-2 infection in the primary care setting, from diagnosis to treatment, applying also the recommendations of the Italian Society of General Medicine. | 2020-12-17 |
| 33330341 | It specifically provides the quality of the diagnostic method adopted for the prediction of COVID-19 infections in a patient. | 2020-12-17 |
| 33330564 | Our objective was to determine the accuracy of teledermatology in the 10 most frequent skin neoplasms in our population, comparing telediagnosis to histopathological report and in-person dermatologists’ diagnosis. […] Thirteen teledermatologists who participated in the project had three options to refer the patients: send them directly to biopsy, to the in-person dermatologist, or back to the general physician with the most probable diagnosis and management. […] In the groups referred to the in-person dermatologist and biopsy, we looked for the 10 most frequent International Statistical Classification of Diseases and Related Health Problems-10 (ICD-10) of skin neoplasms, which resulted in 289 histopathologic reports and 803 in-person dermatologists’ diagnosis. […] The proportion of complete, partial, and no agreement rates between the in-person dermatologist’s, histopathologic report, and the teledermatologist’s diagnosis was assessed. | 2020-12-17 |
| 33330604 | A significant decrease in outpatient activity, invasive diagnostic procedures, and endoscopic and major surgeries was reported. | 2020-12-17 |
| 33330645 | We suggest that all these novel Ace2-associated genes and pathways may be targeted for preventive, diagnostic, and therapeutic purposes in cardiovascular damage in patients with systemic inflammation, including COVID-19 patients. | 2020-12-17 |
| 33330782 | Diagnosis is based on detection of SARS-CoV-2 by polymerase chain reaction (PCR) testing of nasopharyngeal swabs or sputum. | 2020-12-17 |
| 33330783 | Online diagnosis and treatment platforms provided by companies cover most of the regions in China. […] During the prevention and control of this epidemic, online diagnosis and treatment has filled the gap of family doctors in epidemic prevention and control, it has reduced the chance of cross-infection of patients with a mild infection, and it has overcome the geographical limitations of medical resources. […] However, online diagnosis and treatment still faces challenges in terms of resource allocation and industry supervision. | 2020-12-17 |
| 33330797 | The importance of laboratory diagnostic capacity for effective infectious disease control has been widely recognized in recent years, but many of the countries still struggled to establish it when the newly discovered diseases was happened, such as coronavirus disease 2019 (COVID-19). […] Even in the country that the laboratory system was highly evaluated by Global Health Security Index like Myanmar, support from external partners is essential to establish the diagnostic capacity for COVID-19. […] WHO and other contributors, including Japan, have been supporting the establishment of a diagnostic system for SARS-CoV-2 in response to the disease outbreak. […] The first confirmed diagnosis was reported on March 23, and 15 positive cases as of March 31. […] Since it is difficult to control the outbreak in a given country without controlling it in the neighboring countries, continuous international cooperation for establishing the coronavirus disease 2019 diagnostic capacity was crucial despite the challenges of fighting the outbreak in home countries. | 2020-12-17 |
| 33330811 | However, FDG-PET/CT cannot be routinely used in an emergency setting and is not generally recommended as a first choice for diagnosis of infectious diseases. | 2020-12-17 |
| 33331072 | Clinicians may warn the exacerbation of COVID-19 facing above risk factors and associated characteristics, and adjust the diagnosis and treatment plan to delay the disease progression, reduce complications and mortality and improve the prognosis of patients. | 2020-12-17 |
| 33331164 | The viral etiology was nevertheless excluded by repeated nasopharyngeal swabs and serological tests and the final diagnosis was amiodarone induced organizing pneumonia. […] Even during a pandemic, differential diagnosis should always be considered and pulmonary toxicity has to be taken into account in any patient taking amiodarone and who has new respiratory symptoms. | 2020-12-17 |
| 33331264 | Integration of clinical manifestations, history of exposure, laboratory profiles, and dynamic of disease progression assisted the physicians in precise diagnosis. | 2020-12-17 |
| 33331392 | We compared the following health outcomes: self-perception of anxiety or sadness, fear of COVID-19 infection, cancer-related complications during social isolation, self-medication, diagnosis of COVID-19, and death between patients with and without delayed cancer care. | 2020-12-17 |
| 33331401 | COVID-19 is a public health emergency of international concern whose detection in recovered asymptomatic patients is dependent on accurate diagnosis as it enables the estimation of the susceptibility of the population to the infection. […] Correlating the results of rNP and WVA ELISAs resulted in improved performance for COVID-19 diagnosis. […] The choice of antigen is an important aspect in optimizing the laboratory diagnosis of COVID-19. […] IgG serology using several assays, and with the spectral patterns of SARS-CoV-2, resulted in confusing information that must be clarified before the establishment of diagnostic serology criteria. | 2020-12-17 |
| 33331510 | The following descriptors were used: [(pediatrics) AND (emergencies) AND (diagnostic imaging) AND (medical overuse)] and [(Coronavirus infections) OR (COVID-19) AND (pediatrics) AND (emergencies) AND (diagnostic imaging)]. | 2020-12-17 |
| 33331542 | Health professionals are more affected, but they also have greater access to diagnosis; however, data are still scarce on other professional categories, as well as on the social determinants that lead to greater labor-related vulnerability. | 2020-12-17 |
| 33331603 | This was a cross-sectional study using records of flu-like syndrome cases containing results of COVID-19 diagnostic tests in the Brazilian state capitals and Federal District, held on the e-SUS Notifica system, from March 1st, 2020 to August 18th, 2020. | 2020-12-17 |
| 33331654 | Our data will help develop the diagnosis and vaccine of SARS-CoV-2. | 2020-12-17 |
| 33331657 | Samples were taken at the time of diagnosis and analyzed via flow cytometry within 24 hours. | 2020-12-17 |
| 33331665 | We considered all types of empirical studies, which quantitatively assessed impact including epidemiological studies, modelling studies, mixed-methods studies, and diagnostic studies that assessed the impact of relevant interventions beyond diagnostic test accuracy. | 2020-12-17 |
| 33331709 | In times of coronavirus, a patient with respiratory symptoms whose chest CT scan reveals ground-glass opacities, COVID-19 may seem an obvious diagnosis. | 2020-12-17 |
| 33331722 | Early diagnosis is important to provide complementary non-pharmacological interventions (gentle passive mobilization) and medication (non-steroidal anti-inflammatory drugs, such as indomethacin). | 2020-12-17 |
| 33331864 | Reverse transcription-quantitative PCR on nasopharyngeal swabs is currently the reference COVID-19 diagnosis method but exhibits imperfect sensitivity. […] Multiplex RT-ddPCR represents an alternative and complementary tool for the diagnosis of COVID-19, in particular to control RT-qPCR ambiguous results. | 2020-12-17 |
| 33332042 | There are reports of multiple groups of skin lesions presenting in different stages of this diagnosis. […] It is recommended to consider an infection with SARS-CoV-2 in the differential diagnosis in patients presenting with these groups of skin lesions. | 2020-12-17 |
| 33332052 | The municipal public health services of Groningen and Fryslân invited all HCPs aged above 18 years who tested positive for COVID-19 between March 18th and April 3rd 2020 to fill out an online questionnaire (n = 109), on average one month after diagnosis. | 2020-12-17 |
| 33332170 | Adult and pediatric patients diagnosed with COVID-19 with a current or historical diagnosis of malignancy were identified from the electronic medical record at the University of California, San Francisco, and Stanford University. […] The proportion of patients undergoing active cancer management whose care was affected was quantified and analyzed for significant differences with regard to management type, treatment intent, and the time of COVID-19 diagnosis. | 2020-12-17 |
| 33332288 | The FDA has issued emergency use authorization (EUA) for hundreds of COVID-19 diagnostic tests of different classes. […] Whereas nucleic acid testing (NAT) such as RT-PCR remains the criterion standard for COVID-19 diagnosis, serological antibody and antigen tests are increasingly being developed. […] Tests based on the novel RNA sensing techniques (e.g., SHERLOCK, DETECTR, and Toehold Switch) are promising due to their relatively low cost, high accuracy, and rapid detection time. […] Diagnostic testing results for SARS-CoV-2 should be interpreted with caution, since they depend heavily on factors such as viral load, virus replication, the source and timing of sample collection, sample extraction, and characteristics of various testing methods. […] This review aims to present the current status of common diagnostic testing for SARS-CoV-2 infection, review the current regulatory requirements, and identify future directions in the development of improved diagnostics that are more accurate, accessible, and rapid. | 2020-12-17 |
| 33332331 | The observed reduction in ICU admission rates appeared to occur for most categories of ICU admission diagnosis but was not evident for patients with neurologic disorders. | 2020-12-17 |
| 33332412 | The results indicate that careful consideration is required in practical applications of DNNs to COVID-19 diagnosis; in particular, they emphasize the need for strategies to address security concerns. | 2020-12-17 |
| 33332853 | WALANT techniques hold promise for use in future disaster scenarios and should be evaluated for potential incorporation into routine orthopaedic surgical care. | 2020-12-17 |
| 33333012 | COVID-19-associated pulmonary aspergillosis is proposed to be defined as possible, probable, or proven on the basis of sample validity and thus diagnostic certainty. […] Our aim is to provide definitions for clinical research and up-to-date recommendations for clinical management of the diagnosis and treatment of COVID-19-associated pulmonary aspergillosis. | 2020-12-17 |
| 33333189 | We observed an important reduction in elective and urgent interventions compared to the same period of the previous year; in parallel, we observed an increase in the diagnosis of deep vein thrombosis (DVT) in hospitalized patients, especially with severe infection. | 2020-12-17 |
| 33333331 | To safeguard the supply chain of PPEs, several decontamination techniques have been adopted worldwide ensuring their effective reprocessing to prioritize the circular economy within the system. | 2020-12-17 |
| 33333399 | In March 2020, several international organizations started making recommendations regarding the need for prompt coronavirus-based diagnosis in order to prevent its spread among the world’s population. […] We classified and estimated the amount of plastic residues generated as a consequence of COVID-19 diagnostic tests and analyzed the relationships of the plastics generated with number of confirmed cases, population size, and gross domestic product in each country. […] About 97% of the plastic residues from diagnostic tests for coronavirus are incinerated due to their hazardous nature to humans, but toxic chemicals are released into the environment during the process. | 2020-12-17 |
| 33333471 | Cases with acute longitudinally extensive transverse myelitis (LETM) have been recently reported in SARS-CoV-2 infection but did not fulfill the international consensus diagnostic criteria for NMOSD. | 2020-12-17 |
| 33333506 | The effects and significance levels were comparable in nearly all different diagnostic subgroups according to the ICD codes. […] For cancer diagnosis and treatment, we found a statistically significant decrease in hospital admissions in the range of 10-20% for both study periods in comparison to the previous year. | 2020-12-17 |
| 33333674 | In the process of dealing with epidemic situation, medical laboratories have played an important role in disease diagnosis, treatment, efficacy evaluation and prognosis judgment and so on. […] Beijing Youan Hospital, as the designated hospital of the coronavirus disease 2019 (COVID-19), has set up an emergency laboratory in the capital for the prevention and control of the COVID-19 by carrying out routine tests and virus nucleic acid tests, it provides timely and effective evidence for clinical diagnosis and treatment. | 2020-12-17 |
| 33333879 | Rising rates of maternal overweight and obesity, increasing maternal age and the diversity of ethnicity are key epidemiological impactors, overlaid by the 2015 changes in screening and diagnostic parameters. | 2020-12-18 |
| 33334135 | The present study aimed to assess the diagnostic usability of rapid tests for the detection of antibody against SARS-CoV-2 through comparison of their results with the results of reverse transcription polymerase chain reaction (RT-PCR) test for the detection of SARS-CoV-2 genomic RNA and with the results of a quantitative test for antibody detection. […] All the antibody tests exhibited poor sensitivity at the timing of initial RT-PCR diagnosis. […] All antibody tests were unsatisfactory to replace RT-PCR for the early diagnosis of COVID-19. […] Diagnostic usability of rapid antibody tests for COVID-19 should be investigated rigorously. | 2020-12-18 |
| 33334241 | -test, and ANOVA analysis techniques to analyze differences within position and demographic variables. | 2020-12-18 |
| 33334357 | All patients aged 20-75 years with the diagnosis of Covid-19 based on the PCR test. | 2020-12-18 |
| 33334375 | We aimed to determine the prognosis of patients with current or previous cancer with either a PCR-confirmed COVID-19 infection or a probable diagnosis according to chest CT scan. , 2020. | 2020-12-18 |
| 33334391 | The effects on emergency and elective caseload, intensive care unit (ICU) admissions from theatre, theatre cancellations and regional techniques were noted. […] Theatre caseload decreased by 30% from January to April 2020 (p=0.02), ICU admissions remained constant, and theatre cancellations were proportionally reduced, as were the absolute number of regional techniques. | 2020-12-18 |
| 33334773 | A diagnosis of Kawasaki disease (KD) should be considered in infants with exanthematous fever. […] Physicians should consider a diagnosis of KD if BCG site reactivation is noted in children presenting with febrile exanthema. | 2020-12-18 |
| 33335187 | Accurate, reliable and rapid detection of SARS-CoV-2 is essential not only for correct diagnosis of individual COVID-19 disease but also for the development of a rational strategy aimed at lifting confinement restrictions and preparing for possible recurrent waves of viral infections. | 2020-12-18 |
| 33335206 | In this study, multiple thermal analytical techniques have been implemented to acquire the thermodynamic parameters of 3CLpro at different buffer conditions. | 2020-12-18 |
| 33335637 | The patient developed a supraventricular arrhythmia, and the diagnosis and management of the arrhythmia was done online. | 2020-12-18 |
| 33335829 | Since the declaration of a global pandemic, a lot has been learnt about its spread, disease pattern, diagnosis and management. […] There are a range of imaging modes useable in diagnosis, prognosis, monitoring, and therapy of Covid-19. […] This case highlights the role played by the thoracic ultrasound in the diagnosis and progression of Covid-19 pneumonia. | 2020-12-18 |
| 33336011 | This study is helpful for early diagnosis and timely clinical management by mastering the typical imaging of novel coronavirus disease (COVID-19). | 2020-12-18 |
| 33336017 | However, after a long period of intensive diagnosis and treatment in clinics and due to physical exertion and tiredness, problems such as improper operation are prone to occur during the tedious PPE doffing, thereby producing a relatively high risk of infection. | 2020-12-18 |
| 33336029 | This report described the clinical course of two COVID-19 patients and the purpose of the study was to discuss the combination of chest CT and clinical features for diagnosis of COVID-19. […] Our study shows that chest CT has high sensitivity for diagnosis of COVID-19 in clinical practice, particularly when the nucleic acid test is negative. […] The chest CT should be considered as a diagnostic tool for the COVID-19 screening, comprehensive evaluation, and follow-up and patients would benefit from effective treatments in time. | 2020-12-18 |
| 33336038 | Early diagnosis and treatment are crucial for the survival of severe Coronavirus Disease 2019 (COVID-19) patients, but data with regard to risk factors for disease progression from milder COVID-19 to severe COVID-19 remain scarce. | 2020-12-18 |
| 33336385 | Despite being widely used as a screening tool, a rigorous scientific evaluation of infrared thermography for the diagnosis of minimally symptomatic patients suspected of having COVID-19 infection has not been performed. […] Thirty-four patients had an RT-PCR confirmed diagnosis of COVID-19 and 26 had negative test results. | 2020-12-18 |
| 33336772 | The epidemiological characteristics were as follows: (1) the median incubation period was 8 days (with an interquartile range of 4-12 days); (2) the incubation period in one case was ≥18 days; (3) one infant patient was asymptomatic prior to their diagnosis; and (4) two asymptomatic patients had a positive nucleic acid test after their family members were diagnosed with COVID-19. | 2020-12-18 |
| 33336775 | Furthermore, US research is more geared toward detection techniques and mathematical models, China focuses more on monitoring the epidemic situation, and EU engages in both. | 2020-12-18 |
| 33336778 | Isolation of contaminated workers and healthcare professionals requires clinical and diagnostic criteria. […] On the other hand, interrupting the isolation of healthcare employees and professionals is critical because diagnostic tests do not support clinical decisions. […] Uncertainty about natural and herd immunity to the disease leads to the development of appropriate antivirals, diagnostic tests and vaccines. | 2020-12-18 |
| 33336779 | Here the objective is to analyze the infection trend of flights from a regional data set and discuss the solutions for diagnosis and travel medicine. […] The public data was applied for trend analysis and new solutions were provided based on the current diagnosis information and resembling cancer diagnosis. […] Hotel, mandatory PPE, airport diagnosis, rapid imaging/biomarker diagnosis by advanced high-technology and emergency-travel medicine department are suggested as solutions. […] SARS-CoV-2 prevention in flights needs multiple solutions by potential on-site diagnosis and urgent establishment of a travel medicine unit at airport. | 2020-12-18 |
| 33337442 | Following the principle of territoriality, laboratories of molecular diagnosis were created in the provinces that did not have it. […] Free medical care and treatment; the preparation of a single national intersectoral government plan; the use of particular strategies for research, diagnosis and case tracing; and the implementation of a universal protocol for disease prevention and treatment of confirmed cases allowed to control the disease with a perspective of equity in health. | 2020-12-18 |
| 33337474 | Inpatients were identified using COVID-19 ICD-10-CM diagnosis codes. […] Among 66,646 (6.5%) admissions with a COVID-19 diagnosis, across 613 U.S. hospitals, 12,388 (18.6%) died in-hospital. | 2020-12-18 |
| 33337579 | Flipped classroom techniques, with multiple hands-on exercises, were developed for first-year medical students (MD/PhD [n = 9], Clinical and Translational Research Pathway (CTRP) students [n = 9]). | 2020-12-18 |
| 33338078 | Participants with a previous diagnosis of ALRTIs were recruited from three primary health care centres in Barcelona and one in Tarragona. | 2020-12-18 |
| 33338439 | In addition, cases were excluded when a direct link to SARS-CoV-2 infection could not be established or an established alternate diagnostic cause could be hypothesised. | 2020-12-18 |
| 33338544 | Serologic techniques can serve as a complement to diagnose SARS-CoV-2 infection. […] The objective of our study was to compare the diagnostic performance of six immunoassays to detect antibodies against SARS-CoV-2: three lateral flow immunoassays (LFAs), one ELISA and two chemiluminescence assays (CLIAs). […] Agreement between techniques was evaluated using the kappa score (k). […] One Step, Dia.Pro, Elecsys and COV2T obtained the best diagnostic performance results. […] All these techniques showed a specificity of 100 % and sensitivities over 97 % from 14 days after the onset of symptoms, as well as excellent levels of agreement. | 2020-12-18 |
| 33338856 | Twenty-one (42.0%) patients had active disease at COVID-19 diagnosis, while 25 (50.0%) had no evidence of disease (NED), and 4 (8.0%) were unknown. | 2020-12-18 |
| 33338954 | The case series cited above implicates that TTS should be considered in the differential diagnosis across the entire spectrum of myocardial injury in SARS-CoV-2 infected patients. | 2020-12-18 |
| 33339330 | The elevation of aspartate aminotransferase (AST) or alanine aminotransferase (ALT) to the highest level between COVID-19 diagnosis and hospital discharge was categorized according to a standardized toxicity grade scale. […] Of these patients, 225 (28.1%) developed LEE of grade ≥2 after a median of three days (interquartile range (IQR): 0-8 days) from the diagnosis of COVID-19, and they were estimated to have a higher hazard of death or ICU admission (adjusted hazard ratio (aHR): 1.46, 95% confidence interval (CI): 1.14-1.88). | 2020-12-19 |
| 33339391 | This new scenario will require rapid, inexpensive diagnostic systems, applicable anywhere in the world and, preferably, without the need for specialized personnel. | 2020-12-19 |
| 33339468 | In three days at the beginning of the COVID-19 pandemic, the Copenhagen Emergency Medical Services developed a digital diagnostic device. […] This paper reflects on the uncertain aspects of the performance, risks and issues of accountability pertaining to the digital diagnostic device in order to draw lessons for future improvements. | 2020-12-19 |
| 33339516 | Here, we describe the cases of two children with DS and a confirmed COVID-19 diagnosis who had a severe course. | 2020-12-19 |
| 33339521 | Therefore diagnostic testing is central to contain the global pandemic. […] Up to now real-time reverse transcriptase polymerase chain reaction-based molecular assays for detecting SARS-CoV-2 in respiratory specimens is the current reference standard for COVID-19 diagnosis. […] In HHT patients undergoing a diagnostic test to evaluate the SARS-CoV-2 infection status, especially in those patients with frequent epistaxis with a history of anemia and repeated hospitalizations, it is therefore advisable to perform an oropharyngeal swab. […] According to the risk-benefit assessment and based on our experience, we consider that, despite a lower diagnostic sensitivity, oropharyngeal swab is preferable to nasopharyngeal swab for the diagnosis of SARS CoV-2 infection in patients with HHT. | 2020-12-19 |
| 33339534 | Both complications occurred quite late after COVID-19 diagnosis and were probably precipitated by systemic inflammation, as indicated by a significant delayed increase in inflammatory markers, including interleukin-6 (IL-6). | 2020-12-19 |
| 33339622 | Although the diagnosis of infection with SARS-CoV-2 is microbiological, imaging techniques play an important role in supporting the diagnosis, grading the severity of disease, guiding treatment, detecting complications, and evaluating the response to treatment. | 2020-12-19 |
| 33339696 | As there are clinically reported cases of asymptomatic carriers of SARS-CoV-2, fast and accurate diagnosis plays an important role in the control and further prevention of this disease. […] Herein, we present recent technologies and techniques that have been implemented for the diagnosis of COVID-19. […] Finally, we propose some promising techniques that could potentially be applied to the detection of SARS-CoV-2, and tracing the asymptomatic carriers of COVID-19 rapidly and accurately in the early stages of infection, based on reviewing the research studies on the detection of similar infectious viruses, especially severe acute respiratory syndrome (SARS) coronavirus, and Middle East respiratory syndrome (MERS) coronavirus. | 2020-12-19 |
| 33339741 | Over a period of 4 months, 127 patients with diabetes and 127 individuals without diabetes with a diagnosis of COVID-19 were recruited. | 2020-12-19 |
| 33339871 | Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy was used as a guideline for conducting this systematic review. […] We searched peer-reviewed and preprint articles in PubMed, BioRxiv and MedRxiv up to 28 September 2020 to identify studies that provide data to calculate sensitivity, specificity and diagnostic odds ratio (DOR). […] Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) was applied for assessing quality of included studies and Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies (PRISMA-DTA) was followed for reporting. […] Diagnostic specificities were high (> 0.95) for included studies while sensitivities varied depending on type of assays and sample used. […] Diagnostic performances by CRISPR and RT-LAMP on purified RNA were similar. […] Other diagnostic platforms including RT- recombinase assisted amplification (RT-RAA) and SAMBA-II also offered high sensitivity (> 0.95). | 2020-12-19 |
| 33339931 | The natural progression of conditions such as caries and periodontitis is inevitable without diagnosis and management. | 2020-12-19 |
| 33340034 | Using techniques including computed tomography imaging, immunophenotyping, and alveolar/peripheral cytokine response and immunohistochemical analyses, we delineated cellular immune responses to SARS-CoV-2 infection in macaque and baboon lungs, including innate and adaptive immune cells and a prominent type-I interferon response. | 2020-12-19 |
| 33340166 | Seldom performance evaluation and diagnosis comparison studies were reported for different chemiluminescent immunoassay (CLIA) kits approved under an emergency approval program for SARS-CoV-2 infection. […] ROC analysis indicated all kits had a diagnostic power greater than 0.9. […] The performance of CLIA kits satisfied the diagnosis of SARS-CoV-2 infection. | 2020-12-19 |
| 33340312 | The diagnosis of COVID-19 is based on the detection of SARS-CoV-2 in respiratory secretions, blood, or stool. | 2020-12-19 |
| 33340765 | Because cyclization can increase the protease resistance of peptides, novel IL-6R-binding mClPh-cyclized peptides discovered in this study have the potential to be used for a variety of research, therapeutic, and diagnostic applications involving IL-6/IL-6R signaling. | 2020-12-19 |
| 33340854 | Among the top 50 cited articles, the most common study type, topic of study, publication year, and keyword were, respectively, original scientific paper (n = 26), definition-diagnosis of malnutrition (n = 17), 2010 (n = 13), and malnutrition (n = 18). | 2020-12-19 |
| 33341155 | The diagnosis of COVID-19 (International Classification of Diseases [10th edition] codes U07.10, U07.11, U07.12, U07.14, or U07.15) or influenza (J09, J10, or J11) comprised primary, related, or associated diagnosis. | 2020-12-20 |
| 33341205 | With most of the hospital’s outpatient services closed, the routine clinical diagnosis and treatment for patients with dermatomyositis has been disturbed. | 2020-12-20 |
| 33341212 | This contribution will discuss possible causes of pernio and pernio-like lesions and offer suggestions for appropriate diagnostic workup and management when indicated. | 2020-12-20 |
| 33341460 | In this review we provide both a historical overview of the application of nanomedicine to respiratory diseases and more recent cutting-edge approaches such as nanoparticle-mediated combination therapies, novel double-targeted nondrug delivery system for targeting, stimuli-responsive nanoparticles, and theranostic imaging in the diagnosis and treatment of pulmonary diseases. | 2020-12-20 |
| 33341481 | In this devastating situation, precautionary measures, early diagnosis, and repurposed drugs appear to be timely and decisive factors by which to handle this problem until the discovery of an effective, dedicated vaccine or medicine is made. […] Based on the available literature, this review article sought to highlight the current understanding of the origin, transmission, diagnosis, precautionary measures, infection and drug action mechanisms, therapeutic role, and toxicities of targeted drugs for the prevention and cure of COVID-19. | 2020-12-20 |
| 33341505 | The results of this survey pointed out a significant delay of lung cancer diagnosis along with a relevant reduction of patients’ accrual within clinical trials. | 2020-12-20 |
| 33341806 | We performed a retrospective cohort study of adult patients with COVID-19 diagnosis admitted to the intensive care unit (ICU) between March 2020 and May 2020. | 2020-12-20 |
| 33342313 | LYM count was found to be low in a significant number of patients (57.5%) especially in the ICU group and as an important risk factor and diagnostic parameter on admission to ICU (OR: 125, AUC: 0.74). […] Routine laboratory tests provide important information in terms of both diagnosis and severity of COVID-19. | 2020-12-21 |
| 33342437 | Analysis revealed a confusing illness with many, varied and often relapsing-remitting symptoms and uncertain prognosis; a heavy sense of loss and stigma; difficulty accessing and navigating services; difficulty being taken seriously and achieving a diagnosis; disjointed and siloed care (including inability to access specialist services); variation in standards (e.g. inconsistent criteria for seeing, investigating and referring patients); variable quality of the therapeutic relationship (some participants felt well supported while others felt “fobbed off”); and possible critical events (e.g. deterioration after being unable to access services). | 2020-12-21 |
| 33342449 | Recent European Society of Parenteral and Enteral Nutrition guidelines highlighted the interest of prevention, diagnosis and treatment of malnutrition in the management of coronavirus disease 19 (COVID-19) patients. […] Patients were divided into two groups according to the diagnosis of malnutrition. | 2020-12-21 |
| 33342483 | Radiological examinations have a significant role in the diagnosis and management of Coronavirus disease 2019 (COVID-19), the disease caused by the novel coronavirus SARS-CoV-2. […] This is especially so in resource-limited settings where access to molecular diagnostic techniques such as Reverse Transcription Polymerase Chain Reaction (RT-PCR) is not optimal. […] Importantly, these findings were frequently obtained before PCR diagnosis. […] Chest CT scan can help in the diagnosis and triaging of suspected or confirmed COVID-19 patients in jurisdictions with limited PCR diagnostic capacity and can improve early isolation, contact tracing and treatment thus helping to reduce community spread, morbidity and mortality. | 2020-12-21 |
| 33342517 | This paper examines how estimates from data and models of time-evolving reproduction numbers of national COVID-19 infection spread change by using different techniques and assumptions. […] Given the importance acquired by reproduction numbers as diagnostic tools, assessing their range of possible variations obtainable from the same epidemiological data is relevant. | 2020-12-21 |
| 33342518 | The proposed framework is model-free and applies Early Warning Detection Systems (EWDS) techniques to detect changes in the territorial spread of infections in the very early stages of onset. | 2020-12-21 |
| 33342643 | Varieties of diagnostic protocols are being developed for the diagnosis of COVID-19. […] Many of these diagnostic protocols however, have limitations such as for example unacceptable no of false-positive and false-negative cases, particularly during the early stages of infection. […] At present, the real-time (quantitative) reverse transcriptase-polymerase chain reaction (RT-PCR) is considered the gold standard for COVID-19 diagnosis. […] To overcome the current challenges, the authors propose a diagnostic protocol based on Surface-enhanced Raman Spectroscopy (SERS) coupled with microfluidic devices containing integrated microchannels functionalized either with vertically aligned Au/Ag coated carbon nanotubes or with disposable electrospun micro/nano-filter membranes. […] This would be a valuable diagnostic tool not only for mass screening of current COVID-19 pandemic but also in viral pandemic outbreaks of future. | 2020-12-21 |
| 33342702 | Recently, the 2019 novel coronavirus (COVID-19) pandemic has shined a spotlight on CLIA-waived diagnostic testing. […] To meet this increased patient demand for diagnostic testing, the U.S. | 2020-12-21 |
| 33342753 | We assessed four outcomes: COVID-19 diagnosis; hospital admission with COVID-19; hospital admission with pneumonia; and hospital admission with pneumonia, acute respiratory distress syndrome, acute kidney injury, or sepsis. […] Among 1 355 349 antihypertensive users (363 785 ACEI or ARB monotherapy users, 248 915 CCB or THZ monotherapy users, 711 799 ACEI or ARB combination users, and 473 076 CCB or THZ combination users) included in analyses, no association was observed between COVID-19 diagnosis and exposure to ACEI or ARB monotherapy versus CCB or THZ monotherapy (calibrated hazard ratio [HR] 0·98, 95% CI 0·84-1·14) or combination use exposure (1·01, 0·90-1·15). […] No clinically significant increased risk of COVID-19 diagnosis or hospital admission-related outcomes associated with ACEI or ARB use was observed, suggesting users should not discontinue or change their treatment to decrease their risk of COVID-19. | 2020-12-21 |
| 33342977 | When a patient during anticancer therapy develops pneumonia, we need to cite, as differential diagnosis, anti-cancer drug induced lung injury as well as various pulmonary diseases such as viral pneumonia, bacterial pneumonia, pneumocystis pneumonia, and fungal pneumonia. | 2020-12-21 |
| 33342978 | Also, the fewer cancer diagnosis for cancer has suggested. […] The delay of cancer diagnosis will lead to presentation at more advanced stages and poor outcomes. | 2020-12-21 |
| 33343204 | The current COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to distinct diagnostic and management challenges for front-line healthcare workers. […] Serial inflammatory markers in conjunction with anti-phospholipid antibody testing is critical for the diagnosis of APS in this emerging patient population. […] Our case report reviews details suggestive of APS in the setting of SARS-CoV-2 and aims to provide clinical diagnostic clues that could help warrant further workup and assist with management strategies. | 2020-12-21 |
| 33343358 | Empirical diagnostic and prognostic systems have yet to be validated in the field of periodontics. […] Early diagnosis and intervention prevents periodontitis progression in most patients. […] This review highlights new developments in oral biomarker discovery and their validation for clinical application to advance precision oral medicine through improved diagnosis, prognosis and patient stratification. | 2020-12-21 |
| 33343395 | Measurements collected in this framework ultimately aim to inform predictive computational models and enable the effective development of ventilators and early diagnostic strategies. | 2020-12-21 |
| 33343414 | Stigma impacts health-related outcomes, not only as a barrier to receiving the timely diagnosis and appropriate treatment but also as an important variable that increases mental health issues such as anxiety and depression. | 2020-12-21 |
| 33343415 | An online survey using snowball sampling techniques was conducted during 15 days between March and April 2020, representing the early phase of the quarantine associated with COVID-19 outbreak. | 2020-12-21 |
| 33343657 | At present, even in low-income countries, diagnostic and medical services are becoming more accessible and available. […] Digital platforms can help optimize diagnosis, consulting, and treatment of patients. | 2020-12-21 |
| 33343780 | To control the spread of the pandemic and to choose a suitable treatment plan, a fast, accurate, effective, and ready-to-use diagnostic method has become an important prerequisite. […] In this Review, we introduce the principles of multiple off-site and on-site detection methods for virus diagnosis, including qPCR-based, ELISA-based, CRISPR-based methods, etc. […] We also summarize currently available diagnostic methods for the detection of SARS, MERS, and COVID-19. […] Finally, we hope that understanding of current microfluidic-based detection approaches can help physicians and researchers to develop advanced, rapid, and appropriate clinical detection techniques that reduce the financial expenditure of the society, accelerate the examination process, increase the accuracy of diagnosis, and eventually suppress the worldwide pandemic. | 2020-12-21 |
| 33343799 | To improve practices, WAHO has organized regional training workshops on laboratory diagnostic, surveillance and simulation exercises of outbreak response for key actors, as well as webinars on different aspects of COVID-19 pandemic surveillance, coordination and management. | 2020-12-21 |
| 33343851 | For the last few years, computer-aided diagnosis (CAD) has been increasing rapidly. […] A quick, safe, and accurate early-stage diagnosis of leukemia plays a key role in curing and saving patients’ lives. […] The system allows real-time coordination for testing, diagnosis, and treatment of leukemia among patients and healthcare professionals, which may save both time and efforts of patients and clinicians. | 2020-12-21 |
| 33344389 | Most patients had a clinical history of exposure to COVID-19 patients and/or SARS-COV2 biological diagnosis. | 2020-12-21 |
| 33344540 | Chest radiography and computed tomography play an important role in disease diagnosis, differential diagnosis, severity evaluation, prognosis prediction, therapeutic effects assessment and follow-up of patients with COVID-19. | 2020-12-21 |
| 33344544 | The patients were diagnosed according to the World Health Organization interim guidance and critical cases met any one of the following criteria: Respiratory failure and required mechanical ventilation, the occurrence of shock, and the combined failure of other organs that required intensive care unit monitoring and treatments, according to the diagnostic criteria of critical COVID-19. | 2020-12-21 |
| 33344581 | In the two cohorts of HCV patients, COVID-19 diagnosis was made in 0.07% of those with liver disease and 1% of those with cirrhosis. | 2020-12-21 |
| 33344605 | The deviation of the nucleic acid test by throat swab (the current gold standard of COVID-19) caused by variation in sampling techniques and reagent kits and coupled with nonspecific clinical manifestations make confirmation of the suspected cases difficult. | 2020-12-21 |
| 33344608 | The diagnosis of CoVID-19 was made based on laboratory results, chest CT images, clinical manifestations and epidemiologic characteristics. […] CT is an acceptable method for the primary diagnosis and treatment should be initiated as soon as possible. | 2020-12-21 |
| 33344676 | This article lays a concrete emphasis on reviewing the limited published literature that is specific to the pediatric population regarding epidemiology, pathogenesis, diagnosis, and treatment modalities of COVID-19. | 2020-12-21 |
| 33345364 | In our experience, this digitally-enabled dermatopathology practice revealed myriad benefits, including an improved diagnostic workflow and increased access to teaching. […] Whole slide imaging (WSI) is a related system that digitizes glass slides with high resolution and has been clinically validated for primary diagnosis. | 2020-12-21 |
| 33345619 | However, teleconsultation has some major limitations and drawbacks, especially for ocular surface assessment that relies on high-quality graphic data for adequate diagnosis. | 2020-12-21 |
| 33346080 | The purpose of this study was to examine the impact of COVID-19 on lung cancer screening and subsequent cancer diagnosis. | 2020-12-21 |
| 33346100 | Using several in silico techniques, we proposed prospective therapeutics against this virus. | 2020-12-21 |
| 33346244 | To determine the probabilities of transition between different types of care and diagnostic states for the population infected with COVID-19 in Colombia, by age group. | 2020-12-21 |
| 33346606 | There was a 65% reduction across all services; 97.6% of respondents reported some reduction in diagnostic procedures and 71.3% reduction in therapies; 85% worked with a reduced workforce. | 2020-12-21 |
| 33346711 | Nucleic acid detection techniques are always critical to diagnosis, especially in the background of the present coronavirus disease 2019 pandemic. […] Simple and rapid detection techniques with high sensitivity and specificity are always urgently needed. […] However, current nucleic acid detection techniques are still limited by traditional amplification and hybridization. | 2020-12-21 |
| 33346946 | Because the diagnosis of COVID-19 is challenging in children, we recommend pretransplant monitoring of graft recipients and their parents by monthly RT-PCR and serology. | 2020-12-21 |
| 33346956 | During the NCP epidemic, all medical workers are confronted with special challenges in the diagnosis and treatment of various diseases and required of even more accurate therapeutic protocols as well as stricter observation of the principles for the prevention and control of NCP. […] Therefore, the Andrology Branch of Chinese Medical Association convened relevant experts to summarize the special points for andrologic clinicians to attend to in the diagnosis and treatment of male diseases during the NCP epidemic. | 2020-12-21 |
| 33347032 | Of the 291 participants (median age of 55 [43.5-63] years, 93.8% females), limited systemic sclerosis was the most common diagnosis (42.3%). | 2020-12-21 |
| 33347935 | Quantitative reverse transcription polymerase chain reaction (qPCR) techniques were employed to measure nucleic acid area densities from a broad range of human adenoviruses and rhinoviruses, as well as coronavirus OC43, influenza A, and norovirus GI. | 2020-12-21 |
| 33348007 | Management of the pandemic caused by the novel coronavirus SARS-CoV-2 challenges both scientists and physicians to rapidly develop, and urgently assess, effective diagnostic tests and therapeutic interventions. | 2020-12-21 |
| 33348224 | Clinical, imaging and laboratory data of 120 patients whose COVID-19 diagnosis based on RT-PCR were evaluated retrospectively. | 2020-12-21 |
| 33348293 | Here, we intended to assess the CAR’s diagnostic power in early differentiation of hospitalized severe COVID-19 cases. […] The calculation of receiver operating characteristic (ROC) curve was used to determine the diagnostic power of CAR in differentiating severity of COVID-19. | 2020-12-21 |
| 33348699 | This review will also discuss the potential for EVs to be exploited as diagnostic and treatment tools for viral infection. | 2020-12-22 |
| 33349108 | Aim of our study was to assess the presence of SARS-CoV-2 RNA in platelets from hospitalized patients with aconfirmed diagnosis of COVID-19. | 2020-12-22 |
| 33349165 | The new mink-associated SARS-CoV-2 variant with a possible reduced sensitivity to neutralizing antibodies poses serious risks and is expected to have a direct effect on the diagnostic techniques, therapeutics, and vaccines that are currently under development. | 2020-12-22 |
| 33349261 | The easy access to a quick diagnosis of coronavirus disease 2019 (COVID-19) is a key point to improve the management of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and to contain its spread. […] Consequently, new diagnostic tools are required. ) is evaluated by a retrospective and a prospective analysis on SARS CoV-2 samples previously assessed with an FDA “authorized for the emergency use-EUA” reference method. | 2020-12-22 |
| 33349271 | The median interval from symptom onset to diagnosis was 10.0 (6.0-14.0) days; the interval from onset to diagnosis gradually shortened. […] The median intervals from diagnosis to death and symptom onset to deaths were 6.0 (2.0-11.0), 17.0 (12.0-22.0) days, respectively. | 2020-12-22 |
| 33349495 | Comparative analysis was carried out evaluating prospective and retrospective consecutively admitted patients with a diagnosis of CFI of odontogenic origin in the COVID-19 lockdown period from 15 March to 15 June 2020 and pre-COVID-19 during the same period of the previous year. | 2020-12-22 |
| 33349562 | Qualitative study with action research methodology, responding to the following algorithm: plan the action, diagnosis of the need and hypothesis-action; apply the action, creation of the group of case managers and training of the members; observe the action, collect and analyse the information. | 2020-12-22 |
| 33349792 | The exploitation of bioinformatics tools and techniques has successfully interpreted this viral genomics architecture. | 2020-12-22 |
| 33349988 | The participants disclosed their COVID diagnosis to different groups, including family, close friends, community members and workplace contacts. | 2020-12-22 |
| 33350316 | The aims of this meta-analysis were to assess: 1) the prevalence of coronavirus disease 2019 (COVID-19) in hip fracture patients; 2) the associated mortality rate and risk associated with COVID-19; 3) the patient demographics associated with COVID-19; 4) time of diagnosis; and 5) length of follow-up after diagnosis of COVID-19. […] A total of 17 studies reported whether a patient presented with COVID-19 (n = 108 patients, 35.1%) or developed COVID-19 following admission (n = 200, 64.9%), of which six studies reported a mean time to diagnosis of post-admission COVID-19 at 15 days (2 to 25). | 2020-12-22 |
| 33350484 | The novel CE marked Aptima SARS-CoV-2 TMA and the LDT for hCoV were validated with 321 diagnostic specimens from the upper and lower respiratory tract in comparison to two SARS-CoV-2 RT-PCRs (PF E-gene RT-PCR and genesig RT-PCR, 157 specimens) or the R-GENE hCoV/hParaFlu RT-PCR (164 specimens), respectively. […] In conclusion, the SARS-CoV-2 TMA and the LDT for hCoV enhanced the diagnostic spectrum of the PF for all coronaviruses circulating globally for a multitude of diagnostic materials from the upper and lower respiratory tract. | 2020-12-22 |
| 33350677 | Both techniques are considered high-risk aerosol-generating procedures and present a heightened risk of exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for operating room personnel. | 2020-12-22 |
| 33351339 | All concerns and anticipated risks are related to the potential impact of COVID-19 on perinatal outcomes, so pregnant women require special attention in relation to the preventive measures, diagnosis and treatment of a new coronavirus disease. | 2020-12-22 |
| 33351775 | This self-administered and cost-effective approach has many advantages over self-report questionnaire-based methods and provides a more objective measure of smell and taste changes associated with COVID-19 infection; this will encourage otherwise asymptomatic individuals who are potential spreaders of the virus to self-isolate and seek formal medical diagnosis if they experience a sudden change in sensory acuity. | 2020-12-22 |
| 33351801 | The increase of new confirmed cases has been consistent during this time period for all provinces, with some demonstrating a sharp increase, in part due to the surge in national diagnostic capacity. | 2020-12-22 |
| 33351802 | All positive cases were isolated, treated and had their contacts traced, which led to early and proactive diagnosis of cases and in turn yielded up to 95-98% asymptomatic cases. | 2020-12-22 |
| 33352102 | We describe the case of a 64-year-old male patient with a diagnosis of IPF under antifibrotic treatment for 1 year; the patient tested positive for COVID-19 with polymerase chain reaction test of the nasopharyngeal swab, and his chest computed tomography results were compatible with COVID-19 pneumonia described in the literature as well as the findings compatible with interstitial lung disease. | 2020-12-22 |
| 33352277 | In this review, we discuss the novel developments and challenges for the diagnosis and treatment of stroke in patients with COVID-19, and delineate the principles for a rational approach toward precision medicine in this emerging field. | 2020-12-22 |
| 33352326 | The outcome measures were the diagnosis of COVID-19 and severe COVID-19. […] Angiotensin receptor blockers were not associated with either the diagnosis of COVID-19 (adjusted OR [aOR], 1.02; 95% confidence interval [CI], 0.90-1.15) or severe disease (aOR, 1.11; 95% CI, 0.87-1.42). | 2020-12-22 |
| 33352569 | Most discharged patients got negative rRT-PCR in nasopharyngeal swabs within 26 days of diagnosis. | 2020-12-22 |
| 33353045 | We present a novel method for modelling epidemic dynamics by a model selection method using wavelet theory and, for its applications, machine learning-based curve fitting techniques. | 2020-12-23 |
| 33353349 | In this study, we will present for the first time, an overview of SRs/MAs, which provides a comprehensive, dynamic evidence landscape on prevalence, prevention, diagnosis, treatment, and prognosis of COVID-19. | 2020-12-23 |
| 33353379 | A limitation of LUS is that it requires practitioners with sufficient competence to ensure timely, safe, and diagnostic clinical/imaging assessments. | 2020-12-23 |
| 33353381 | To perform a systematic review and meta-analysis to compare the diagnostic accuracy of CT and initial reverse transcriptase polymerase chain reaction (RT-PCR) for detecting COVID-19 infection. […] We searched three databases, PubMed, EMBASE, and EMCARE, to identify studies reporting diagnostic accuracy of both CT and RT-PCR in detecting COVID-19 infection between December 2019 and May 2020. […] Pooled diagnostic accuracy of both the tests was calculated by using a bivariate random effects model. = o.ooo1]. […] Since the results of a CT scan are available quickly, it can be used as an adjunctive initial diagnostic test for patients with a history of positive contact or epidemiological history. | 2020-12-23 |
| 33353419 | Fundus examination revealed bilateral venous stasis and dot and blot intra-retinal hemorrhages preceding the diagnosis of COVID-19 in a patient with mild respiratory symptoms that progressed within a few days to a severe respiratory distress. | 2020-12-23 |
| 33353540 | We aim to study the impact of COVID-19 on the utilization of pediatric hospital services including emergency department (ED) attendances, hospitalizations, diagnostic categories and resource utilization in Singapore. | 2020-12-23 |
| 33353731 | Global changes in diagnostic and therapeutic colorectal cancer practices were evident. | 2020-12-23 |
| 33353888 | We also compared the diagnostic tests for Sars-CoV-2. | 2020-12-23 |
| 33353972 | These nanobodies and their derivatives have therapeutic, preventative, and diagnostic potential. | 2020-12-23 |
| 33354060 | TP aims to address the treatment gaps, barriers for utilization, accessibility, diagnostic validity, financial implications, and individual client preferences. | 2020-12-23 |
| 33354252 | Laboratory diagnostic tests and imaging modalities are two test groups used for the detection of COVID-19. […] Among these tests, RdRp/Hel RT-PCR assay had the lowest diagnostic limitation and highest sensitivity and specificity for the detection of SARS-CoV-2 RNA in both respiratory tract and nonrespiratory tract clinical specimens. | 2020-12-23 |
| 33354272 | Physical examination and radiography are essential to diagnosis. […] Awareness of this complication and early diagnosis may help minimize functional impairment. | 2020-12-23 |
| 33354330 | Among the 2336 patients enrolled, 5.5% had confirmed COVID-19 diagnosis. […] Multivariate analysis showed that oxygen therapy on diagnosis and a decrease in lymphocyte count were independent risk factors associated with disease severity and with mortality. | 2020-12-23 |
| 33354349 | Both participants with a diagnosis of psychiatric illness or obesity (body mass index [BMI] ≥ 30) were most likely to report declines in weight gain protective behaviours and show an overall profile of weight management behaviours worsening. | 2020-12-23 |
| 33354370 | Malaria and COVID-19 are major public health issues in Nigeria; more researches on these diseases especially in epidemiology, pathology, diagnosis, treatment, and vaccine production are vital. | 2020-12-23 |
| 33356382 | We conducted a nationwide cohort study using administrative database of all hospitalized patients with main diagnosis of acute ischemic stroke (AIS), transient ischemic attack, or intracerebral hemorrhage. | 2020-12-28 |
| 33356661 | : Diagnosis should rely on PCR and not on clinical presumption. […] Early diagnosis, care, and implementation of an antiviral treatment; the use of immunomodulators at a later stage; and the quality of intensive care are critical regarding mortality rates. | 2020-12-28 |
| 33357041 | Our study contributes to recent discussions about death anxiety as a transdiagnostic factor in psychopathology and yields important implications for psychosocial support in the current pandemic. | 2020-12-28 |
| 33357150 | A diagnosis of COVID-19 was confirmed by polymerase chain reaction. | 2020-12-28 |
| 33357174 | Almost half (49.4%) of those hospitalised with a diagnostic code had pneumonia/lower respiratory tract infection and another 36.6% had an upper respiratory tract infection or other known COVID-19 symptoms. | 2020-12-28 |
| 33357198 | Computed tomography (CT) plays a vital role in the diagnosis. | 2020-12-28 |
| 33357240 | Multi-organ point-of-care ultrasound (PoCUS) including lung ultrasound (LUS) and focused cardiac ultrasound (FoCUS) as a clinical adjunct has played a significant role in triaging, diagnosis and medical management of COVID-19 patients. | 2020-12-28 |
| 33358012 | The times from diagnosis to treatment and the type of initial care were compared too. | 2020-12-28 |
| 33358285 | During the COVID-19 pandemic, electrochemical platforms have shown the potential to address significant limitations of conventional diagnostic platforms, including accuracy, affordability, and portability. | 2020-12-28 |
| 33359083 | Of the 7,334 women who underwent the OGTT between 22 and 30 weeks gestation, 966 had HIP (WHO diagnostic criteria, reference standard). […] SFD proposal sensitivity for HIP diagnosis and the occurrence of HIP-related events (preeclampsia, large for gestational age infant, shoulder dystocia or neonatal hypoglycaemia) in women with false negative (FN) and true positive (TP) HIP-diagnoses were evaluated. | 2020-12-28 |
| 33360025 | Clarification of the pathogenic mechanisms of SARS-CoV-2 is needed to encourage prompt diagnosis and optimized care. | 2020-12-28 |
| 33360242 | SARS-CoV-2 RNA post-mortem detection could have a key diagnostic role in deaths lacking medical assistance, unattended deaths, and patients with multiple comorbidities. | 2020-12-28 |
| 33360269 | Diagnostic accuracy, diagnostic confidence, image quality regarding the assessment of GGO, as well as subjective time-efficiency of MinIP and standard MPR series were analyzed based on the assessment of six radiologists. […] MinIP reconstructions achieved significantly higher ratings by radiologists concerning diagnostic confidence (medians, 5.00 vs 4.00), image quality (medians, 4.00 vs 4.00), contrast between GGO and unaffected lung parenchyma (medians, 5.00 vs 4.00) as well as subjective time-efficiency (medians, 5.00 vs 4.00) compared with MPR-series (all P < .001). | 2020-12-28 |
| 33360731 | Thus, the diagnostic pathologist can use either hematoxylin and eosin stain or immunohistochemistry for caspase 3 and ACE2 to document the endothelial cell damage of COVID-19. | 2020-12-28 |
| 33360865 | Students reported on average worse depressive symptoms during lockdown than 6 months before isolation (median increase in the BDI-2 score +2; IQR = -3, 6; β = 0.09 ± 0.03, p = 0.005), with students without any established diagnosis of psychopathology being affected the most. | 2020-12-28 |
| 33361078 | There is an urgent need to generate evidence for diagnosis and management of this condition in the midst of a pandemic. | 2020-12-28 |
| 33361083 | All patients were followed up for a maximal of 60 days after the diagnosis of COVID-19. […] The primary outcome was all-cause mortality within 60 days after the diagnosis of COVID-19. | 2020-12-28 |
| 33361386 | To discuss the pathogenic and diagnostic relevance of cellular and humoral immune responses against severe acute respiratory syndrome novel coronavirus (SARS-COV-2) and pertinent observations made in progressive multifocal leukoencephalopathy (PML). | 2020-12-28 |
| 33361400 | Surveys collected demographic information, SARS-CoV-2 exposures, and previous COVID-19 diagnosis. […] Participants with a known previous COVID-19 diagnosis showed a decline or loss of IgG antibodies over 2 months. | 2020-12-28 |
| 33361525 | Our results suggest that SARS-CoV-2 may elicit allergic immune responses in patients and that the levels of CRP, PA, LDH, and HBDH, as well as the absolute numbers of CD4 and CD8 lymphocytes could be used as early diagnostic markers of SARS-CoV-2 infection. | 2020-12-28 |
| 33362199 | We suggest quantification of AWC on the low-dose chest CT, which is initially performed for the diagnosis of COVID-19, to screen for patients at risk of severe COVID-19. | 2020-12-28 |
| 33362291 | Interactions of hydroxychloroquin (HCQ) with the receptor binding domain (RBD) of SARS-CoV-2 were studied from atomistic simulation and ONIOM techniques. | 2020-12-28 |
| 33362332 | In contrast, more flexible modelling techniques reveal a robust effect of Covid-19 infections on political trust. | 2020-12-28 |
| 33362345 | It is of great importance to rapidly and accurately segment COVID-19 from CT to help diagnostic and patient monitoring. | 2020-12-28 |
| 33362395 | In the coming years, the use of state-of-the-art technologies will revolutionize routine diagnostic and treatment approaches, as well as have a positive effect on the physician-patient relationship. | 2020-12-28 |
| 33362654 | A rapid review was conducted to identify the most effective stress reduction techniques for health care providers dealing with patients infected with severe coronavirus (SARS, MERS, and COVID-19). […] All empirical quantitative and qualitative studies in which relaxation techniques of various types implemented on health care providers caring for patients during severe coronavirus pandemics and articles that consider the implementation of mental health care services considered to be pertinent, such as commentaries, were included. | 2020-12-28 |
| 33362695 | First, the RT-PCR diagnostic was validated for CSF studies using stringent criteria; and second, 61% of these patients had CSF testing within 1 week of a positive nasopharyngeal diagnostic test. | 2020-12-28 |
| 33362757 | We evaluated the peripheral blood mononuclear cells profile of 63 patients with COVID-19 at diagnosis. | 2020-12-28 |
| 33362916 | Chest X-ray and computed tomography (CT) are the primary imaging tests for diagnosis of SARS-CoV-2 pneumonia, follow-up, and detection of complications. | 2020-12-28 |
| 33362917 | The integrated clinical, laboratory and ultrasound approach is essential for the diagnosis, evaluation and monitoring of the patient’s therapy in coronavirus disease 2019 pneumonia. | 2020-12-28 |
| 33363065 | Although fear from the COVID-19 pandemic determined a delayed diagnosis of serious pediatric diseases, the increasing prevalence and severity of AA were not demonstrated in the most COVID-19-affected areas of Italy. | 2020-12-28 |
| 33363096 | Based on the principles of positive and client-centered psychology, ecotherapy-related techniques have been shown to be effective in medical disorders like hypertension, obesity, post-surgical recovery and psychosocial conditions like depression, stress reduction, post-traumatic stress disorder (PTSD), attention deficit hyperkinetic disorder (ADHD) and adjustment disorders. […] The principles of ecotherapy have been integrated into other psychotherapeutic techniques for better efficacy. […] This review attempts provides an overview of techniques, applications and challenges related to ecotherapy in psychology. | 2020-12-28 |
| 33363098 | In this article, a focus has been made to highlight on current epidemiology on the COVID-19 infection, clinical features, diagnosis, and transmission, with special emphasis on treatment measures of the disease at different stages of clinical research and the global economic influence due to this pandemic situation. | 2020-12-28 |
| 33363278 | Researches are ongoing to develop vaccines and traditional methods of Medicine and Biology have been applied in diagnosis and treatment. […] Thus, further research is required to strengthen the current technologies and there is a strong need for the emergence of a robust computationally intelligent model for early differential diagnosis of COVID-19. | 2020-12-28 |
| 33363279 | The OD provided diagnosis and education, press-on prisms, strategies and modifications, and follow-up recommendations. | 2020-12-28 |
| 33363303 | Accurate diagnostic tests that provide results in a timely manner are essential for the clinical and public health management of COVID-19 diseaseThe choice as to which test to use will depend on the clinical presentation and the stage of the illness Nucleic acid tests, using real-time reverse transcriptase-polymerase chain reaction, are the most appropriate for diagnosing acute infection. | 2020-12-28 |
| 33363440 | The topics of discussion include different detection approaches, methods of signalling and fabrication techniques. | 2020-12-28 |
| 33364090 | Bone marrow biopsy confirmed hemophagocytosis and immunoperoxidase staining established the diagnosis of relapsed Classic Hodgkin’s Lymphoma. | 2020-12-28 |
| 33364102 | The diagnosis of erythema ab igne was made as his mother verified that the child was spending approximately two hours per day playing video games in the cold basement of his house, with a space heater positioned close to his left leg. […] Our case of erythema ab igne is unique due to the relatively young age of the affected child, and it provides an example of how this diagnosis can be made via a telemedicine visit. | 2020-12-28 |
| 33364109 | The diagnosis of typical angina was made in nine patients and they were instructed to seek emergency care. | 2020-12-28 |
| 33364248 | FTA including CDS evaluation contributed to a substantial reduction of PVL in GCA by shortening the time to diagnosis and treatment initiation. | 2020-12-28 |
| 33364275 | A mixture of purposive and snowball techniques facilitated to choose the respondents via email. | 2020-12-28 |
| 33364386 | The objective of this study is to determine the diagnostic yield of the smell dysfunction as screening tool for COVID-19. […] However, it is not really efficient in the screening of SARS-CoV-2 infection and thus, they should not be considered as a single diagnostic instrument. | 2020-12-28 |
| 33364402 | Patient demographics, comorbid medical conditions, COVID-19 diagnosis dates, symptoms, intubation, and tracheostomy status, along with subsequent laryngological symptoms related to voice, airway, and swallowing were collected. […] Unilateral vocal fold immobility was the most common diagnosis (40%), along with posterior glottic (15%) and subglottic (10%) stenoses. 45% of patients underwent further procedural intervention in the operating room or office. | 2020-12-28 |
| 33364604 | The principles of this new practice anchor in analysis of continuous bedside monitoring data, training models on diagnosis-specific paths of deterioration using clinician-identified events, and continuous display of trends in risks rather than alerts when arbitrary thresholds are exceeded. | 2020-12-28 |
| 33364797 | The aim of the present study was to assess the diagnostic performance of an LFA compared with an ELISA test in a cohort of HWs operating in a COVID-19 unit of a teaching hospital in southern Italy. | 2020-12-28 |
| 33365178 | In addition, he had an infiltrate in both lungs consistent with the diagnosis of COVID-19. | 2020-12-28 |
| 33365322 | The current COVID-19 respiratory triage score has marginal diagnostic performance characteristics. | 2020-12-28 |
| 33365357 | Delayed diagnosis led to prolonged hospitalization and extensive antibiotic use. | 2020-12-28 |
| 33365392 | A majority felt that it helped improve their telemedicine communication skills (93%), interpretation of physical exam findings (84%), development of differential diagnosis (95%), and correlation of clinical and basic science content (93%). | 2020-12-28 |
| 33367199 | However, an extension of CT would be associated with increased irradiation doses for the patient, and its diagnostic relevance was unclear. […] This paper adds further evidence to that from other single UK centres that the addition of CT chest for all patients does not yield any further diagnostic information regarding coronavirus. | 2020-12-28 |
| 33367546 | Neither history of transplant, including within a year of COVID-19 diagnosis, nor other anti-MM treatments were associated with outcomes. | 2020-12-28 |
| 33367664 | The use of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serologic tests detects antibodies in the host, contributing to the identification of individuals who have been exposed to coronavirus disease 2019 (COVID-19). | 2020-12-28 |
| 33367803 | The survival gap widened with the follow-up time up to the third to fourth weeks after diagnosis. | 2020-12-28 |
| 33367984 | We modeled the impact of public and private sector contributions to developing diagnostic testing and treatments on COVID-19-related healthcare resource use. […] Private sector contributions to expanded diagnostic testing and treatments led to further reductions in mortality (- 44%), intensive care unit (ICU) and non-ICU hospital beds (- 30% and - 28%, respectively), and ventilator use (- 29%). […] The combination of lower diagnostic test sensitivity and proportions of patients self-isolating may exacerbate case numbers, and policies that encourage self-isolating should be considered. […] While mechanisms exist to facilitate research, development, and patient access to diagnostic testing, future policies should focus on ensuring equitable patient access to both diagnostic testing and treatments that, in turn, will alleviate COVID-19-related resource constraints. | 2020-12-28 |
| 33368021 | It seems COVID-19 leads to a distinct intravascular coagulation syndrome that may need separate diagnostic criteria. | 2020-12-28 |
| 33368088 | This review describes diagnosis and treatment of CAC in the emergency department and in intensive care. | 2020-12-28 |
| 33368236 | This would imply (a) shifting the focus of intervention from symptom reduction and containment of acute crises in a comparatively small number of severe cases to a broader preventive strategy, guided by a gradient of increasing intensity and specificity of treatment; (b) promoting smooth access pathways into services and encouraging participation of families; (c) adopting a transdiagnostic staging model to capture the developmental fluctuations from subsyndromal to syndromal states and back, with related changes in the intensity of the need of care; and (d) implementing digital tools to encourage help-seeking and compliance by digitally native youth. | 2020-12-28 |
| 33368395 | We determined the proportions of donor candidates who passed initial telephone health screening, who qualified after diagnostic testing, who presented to the regional CCP donation center, and who completed CCP donation. […] Of 360 contacted volunteers, 186 (5.7%) were excluded by interview; 133 were referred for additional diagnostic screening, 97 completed donor antibody and antigen testing, and 87 were qualified for CCP donation, resulting in 35 CCP donations (9.7% of initial telephone contacts). | 2020-12-28 |
| 33368603 | CHWs were trained by the NYU College of Dentistry dental hygienist faculty members using dental models and flip charts to instruct patients on proper brushing and flossing techniques. | 2020-12-28 |
| 33368966 | Almost all patients were on antiretroviral therapy (ART) and in 94%, HIV RNA was below 50 copies/mL prior to COVID-19 diagnosis. | 2020-12-28 |
| 33369342 | To investigate the computed tomography (CT) characteristics and differential diagnosis of high altitude pulmonary edema (HAPE) and COVID-19, CT findings of 52 cases of HAPE confirmed in Medical Station of Sanshili Barracks, PLA 950 Hospital from May 1, 2020 to May 30, 2020 were collected retrospectively. […] The size, number, location, distribution, density and morphology of the pulmonary lesions of these CT data were analyzed and compared with some already existed COVID-19 CT images which come from two files, “Radiological diagnosis of COVID-19: expert recommendation from the Chinese Society of Radiology (First edition)” and “A rapid advice guideline for the diagnosis and treatment of 2019 novel corona-virus (2019-nCoV) infected pneumonia (standard version)”. […] In summary, some cloudy shadows are the feature of HAPE CT image, and “crazy paving pattern” and “pleural parallel sign” belong to the COVID-19 CT, which can be used for differential diagnosis. | 2020-12-28 |
| 33369820 | The dental residents had a very good knowledge of the epidemiology, diagnosis, prevention and treatment of COVID-19 and majority of them felt that it would affect their training residency programme. | 2020-12-28 |
| 33369997 | We present a 16-year-old male with H1N1 influenza-induced atypical hemolytic uremic syndrome who quickly improved with complement-blocking therapy, highlighting an urgent need to include TMA in the differential diagnosis of severe viral infections. | 2020-12-28 |
| 33370087 | Collection of nasopharyngeal samples using swabs followed by the transfer of the virus into a solution and an RNA extraction step to perform reverse transcription polymerase chain reaction (PCR) is the primary method currently used for the diagnosis of COVID-19. […] Thus, our electrochemical immunosensor is a promising diagnostic tool for the direct rapid detection of the COVID-19 virus that requires no sample transfer or pretreatment. | 2020-12-28 |
| 33370363 | Participant samples with negative or equivocal results but with analytical signals above the limit of detection and/or previously confirmed COVID-19 diagnosis were also tested for IgG anti-Nucleocapsid. […] Interestingly, among 341 participants with a confirmed COVID-19 diagnosis, 36 (10.55%) tested negative for SARS-CoV-2 IgG (both S1/S2 and recombinant N antigen). | 2020-12-28 |
| 33370645 | Neuroendocrine neoplasms (NENs) are a heterogeneous family of uncommon tumours with challenging diagnosis, clinical management and unique needs that almost always requires a multidisciplinary approach. | 2020-12-28 |
| 33370766 | This review discusses facets of the importance of self-care as mental health first aid tool for health care professionals including doctors and psychologists using research and supportive techniques to help them process stress and anxiety during and after the global pandemic. | 2020-12-28 |
| 33370933 | With improved diagnostic techniques and better disease understanding, an increased number of cases are being reported with extrapulmonary manifestations of this disease ranging from renal and gastrointestinal to cardiac, hepatic, neurological and haematological dysfunction. | 2020-12-29 |
| 33371309 | Innovative measures include the mobile case-tracing application, mobile self-quarantine safety protection application, mobile self-diagnosis application, and drive-thru screening centres. | 2020-12-29 |
| 33371500 | Nuclear medicine techniques can be used for functional imaging of (patho)physiological processes at the cellular or molecular level and for treatment approaches based on targeted delivery of therapeutic radionuclides. | 2020-12-29 |
| 33371524 | From a large cohort of 152 patients consecutively admitted from February to March 2020 for fever and dyspnea to the emergency departments (ED) of three Italian hospitals, we evaluated 85 patients with confirmed diagnosis of COVID-19 and 67 patients with acute illness. | 2020-12-29 |
| 33371667 | A separate section has been included describing the role of nanostructures in biosensing and diagnosis of SARS-CoV-2. […] Based on ongoing research and commercialization of this nanoplatform for a viral disease, the nanomaterials show the potential in therapy, biosensing, and diagnosis of SARS-CoV-2. | 2020-12-29 |
| 33371830 | The review highlights how a variety of NMR-based tools can be employed to better understand viral machineries, develop anti-viral agents and set-up diagnostic and therapeutic routes. […] The review focuses on a subset of human viruses that have been largely studied through NMR techniques. […] In addition, NMR-based metabolomics analyses of biofluids from virus-infected patients let identify metabolites biomarkers of the disease and follow changes in metabolic profiles associated with antiviral therapy thus paving the way for novel diagnostic and therapeutic approaches. | 2020-12-29 |
| 33372181 | Among these 27 proteins, the present study aimed to discover likely antigenic proteins and epitopes to be used for the development of a vaccine or serodiagnostic assay using an in silico approach. […] For this purpose, after the full genome analysis of SARS-CoV-2 Wuhan isolate and variant proteins that are detected frequently, surface proteins including spike, envelope, and membrane proteins as well as proteins with signal peptide were determined as probable vaccine candidates whereas the remaining were considered as possible antigens to be used during the development of serodiagnostic assays. […] Nucleocapsid protein and a highly antigenic GGDGKMKD epitope were identified as ideal antigens to be used in the development of serodiagnostic assays. | 2020-12-29 |
| 33372191 | This finding can be used to determine effective public measures, such as rapid isolation and identification, which are critical since delay of diagnosis is the most common cause of superspreading events. | 2020-12-29 |
| 33372194 | The diagnostic protocol is based on quantitative reverse-transcription polymerase chain reaction (RT-PCR) and chests CT scan, with uncertain accuracy. […] This meta-analysis study determines the diagnostic value of an initial chest CT scan in patients with COVID-19 infection in comparison with RT-PCR. […] Regarding the overall diagnostic sensitivity of 87% for chest CT, the RT-PCR testing is essential and should be repeated to escape misdiagnosis. | 2020-12-29 |
| 33372199 | Comprehensive profiling of humoral antibody response to severe acute respiratory syndrome (SARS) coronavirus-2 (CoV-2) proteins is essential in understanding the host immunity and in developing diagnostic tests and vaccines. […] All the results demonstrate the utility of our microarray as a platform to determine the changes of antibody responses in COVID-19 patients and animal models as well as to identify potential targets for diagnosis and treatment. | 2020-12-29 |
| 33372243 | Lung regions were extracted by U-net, then transformed and fed to pre-trained ResNet-50-based IDANNet (Identification and Analysis of New covid-19 Net) to produce a diagnostic probability. […] The diagnostic threshold to differentiate COVID-19 and non-COVID-19 pneumonia was 0.685 with an AUC of 0.906 (95% CI: 0.886-0.913) in the internal validation group. […] • In the prospective RWD cohort, our DL diagnostic model achieved a sensitivity of 0.811, a specificity of 0.822, and AUC of 0.868 (95% CI: 0.851-0.876), non-inferior to the performance of 3 experienced radiologists. […] • The attention heatmaps were fully generated by the model without additional manual annotation and the attention regions were highly aligned with the ROIs acquired by human radiologists for diagnosis. | 2020-12-29 |
| 33372425 | Per the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) polymerase chain reaction test results, none of the 317 HCWs who came in contact had a confirmed COVID-19 diagnosis (0.00%; 95% confidence interval, 0.00%-0.01%). | 2020-12-29 |
| 33372426 | Severe clinical outcomes were defined as the use of inotropics, conventional oxygen therapy, high-flow nasal cannula, mechanical ventilation, or extracorporeal membrane oxygenation and the development of AKI, cardiac arrest, myocardial infarction, or acute heart failure after the diagnosis of COVID-19. […] AKI was defined as the initiation of renal replacement therapy after the diagnosis of COVID-19 in patients not requiring maintenance dialysis. | 2020-12-29 |
| 33372570 | In terms of professional liability, it is necessary to first clarify that the telemedicine service is comparable to any diagnostic-therapeutic health service considering that the telemedicine service does not replace the traditional health service, but integrates the latter to improve its effectiveness, efficiency and appropriateness. | 2020-12-29 |
| 33372894 | Components of successful interventions include self-monitoring, incorporation of theory and behavior change techniques, and social and professional support. | 2020-12-29 |
| 33372916 | No significant incidences were observed in diagnostic confirmation and treatment in the RCU. | 2020-12-29 |
| 33372924 | Given that both these diseases share many clinical manifestations, in areas where tropical diseases are endemic, it is important to make careful evaluations of the patient who consults for fever in order to establish a timely diagnosis. […] Laboratory diagnostic tests are necessary to take the pertinent measures for each patient. […] Simultaneous infection will worsen the epidemiological situation, and complicate the diagnosis, control and treatment of both diseases. | 2020-12-29 |
| 33373505 | Additional studies are needed to determine the diagnostic capabilities of thromboelastography in patients with NCP. | 2020-12-29 |
| 33373507 | Therefore, fast and accurate diagnosis of infection is key to timely treatment and elimination of the spread of the virus. | 2020-12-29 |
| 33373511 | In this work we tested two reagent kits developed by us for detecting SARS-CoV-2 RNA using a fragment of the ORF1ab gene in digital PCR and real-time PCR formats. […] The developed reagent kits provided 100% sensitivity and a detection limit of 103 GE / ml for qPCR, and at least 200 copies / ml of viral RNA when performing digital PCR. […] It has been shown that dPCR is more sensitive and can be used to analyze samples with low viral load, including those from patients without clinical symptoms. dPCR significantly improves the accuracy of laboratory research and significantly reduces the number of false negative results in the diagnosis of SARS-CoV-2. | 2020-12-29 |
| 33373555 | First, in the absence of explicit guidance for responding to cases in which there is significant uncertainty or disagreement about the relative therapeutic, prophylactic or diagnostic merits of available interventions they perpetuate self-defeating practices. | 2020-12-29 |
| 33373680 | People with a prior mental health diagnosis experienced greater psychological distress. | 2020-12-29 |
| 33373728 | The surgical indications included endometrial cancer (n = 11), borderline ovarian tumor (n = 3), early-stage ovarian cancer (n = 1), stage IA cervical cancer after diagnostic conization (n = 1), and an ovarian cyst that turned out to be benign at final histologic examination (n = 1). | 2020-12-29 |
| 33373808 | Modelling of predictors of negative emotions established several risk factors related to demographic variables, personal vulnerabilities, financial stresses, and social distancing perceptions; particularly being young, female, or having a mental illness diagnosis. | 2020-12-29 |
| 33374106 | We encourage researchers to perform research on promising technologies such as artificial intelligence and remote diagnostic devices, which could make more diagnoses and conditions possible to be treated by digital visits. | 2020-12-30 |
| 33374168 | In addition, differential epitopes could be used for the differential diagnosis of SARS-CoV-2 infection. | 2020-12-30 |
| 33374333 | In our opinion, convalescent plasma may be used as a supportive treatment in COVID-19 patients because of the low frequency of adverse effects and availability, but must be given as early from the diagnosis as possible. | 2020-12-30 |
| 33374452 | The clinical outcomes noted were: hospitalization, the use of inotropics, high flow nasal cannula, conventional oxygen therapy, mechanical ventilation, extracorporeal membrane oxygenation, development of acute kidney injury, cardiac arrest, myocardial infarction, acute heart failure, pulmonary embolism, and disseminated intravascular coagulation after the diagnosis of COVID-19. | 2020-12-30 |
| 33374492 | For diagnosing SARS-CoV-2, this type of AI is critical for optimizing PCR tests because it enables rapid diagnosis and reduces false positives. | 2020-12-30 |
| 33374612 | Current standard diagnostic methods are inadequate for widespread testing as they suffer from prolonged turn-around times (>12 h) and mostly rely on high-biosafety-level laboratories and well-trained technicians. […] Due to the COVID-19 pandemic, POC technologies have been rapidly innovated to address key limitations faced in existing standard diagnostic methods. | 2020-12-30 |
| 33374748 | The summary of pathological, clinical, immunological, and molecular accounts discussed in this review is of theranostic importance to clinicians for early diagnosis of COVID-19 and its management. | 2020-12-30 |
| 33374759 | Additionally, we have reviewed various aspects of patient management strategies including mechanism of action, available diagnostic tools, etc., and also discussed different strategies for the development of effective vaccines and therapeutic combinations to deal with this viral outbreak. | 2020-12-30 |
| 33375040 | Our goal was to assess whether the tools routinely used to monitor our hemodialysis patients could represent reliable and quickly accessible diagnostic indicators to improve the management of our hemodialysis patients in this pandemic environment. […] In this prospective observational diagnostic study, we recruited patients from La Conception hospital. | 2020-12-30 |
| 33375308 | By using a reverse transcription polymerase chain reaction assay, we detected two SARS-CoV-2 RNA positive samples in a room where a COVID-19 patient stayed prior to diagnosis. | 2020-12-30 |
| 33375405 | Participants were recruited by purposeful sampling and snow-ball techniques between May and June 2020. | 2020-12-30 |
| 33375876 | The omics-scale research on COVID-19 has been carried out rapidly, bringing hope for developing a robust diagnostic assay, discovering reliable biomarkers to assess disease progression, and developing therapeutic drugs and vaccines. | 2020-12-30 |
| 33375928 | However, further investigations provided a diagnosis of unusual presentation of ABPA. | 2020-12-30 |
| 33376330 | Fourteen of the most popular colloidal silver products purchased from Amazon (www.amazon.com) were evaluated using state-of-the-art analytical techniques widely accepted as gold standards for investigating the properties (size, shape) and the dispersion of silver nanoparticles. […] Commercial samples were analysed using UV-Vis, FE-SEM and AAS techniques. | 2020-12-30 |
| 33376473 | Timely and accurate diagnosis of COVID-19 is of paramount importance for detecting cases early and to prevent transmission. […] Various clinical laboratory parameters have been investigated for their potential for diagnosis and prognosis of the disease, prediction of complications and monitoring of treatment response. […] Different routine and uncommon parameters have been shown to have the diagnostic and prognostic capacity. […] This update discusses the role of the laboratory in diagnosis, prognosis and monitoring of treatment response. […] Different methodologies for diagnostic testing as well as various clinical laboratory parameters having diagnostic and predictive powers have been discussed. | 2020-12-30 |
| 33376619 | The treatment of this aggressive disease process begins with early diagnosis, where a high index of suspicion is vital. | 2020-12-30 |
| 33376631 | The combination of real-time polymerase chain reaction and the immunoglobulin class M-immunoglobulin class G antibody serology testing can be a powerful strategy for more accurate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection diagnosis with less false results slipping through the cracks. […] The following viewpoint is describing the immunological response to SARS-Cov-2 infection and its implication in the selection of the appropriate diagnosis tools. | 2020-12-30 |
| 33376694 | Based on clinical findings and various diagnostic tests, it is evident that it holds the potential to affect multiple organ systems of the body preferably lungs and immune and coagulation systems. | 2020-12-30 |
| 33376769 | The emergence of SARS-CoV-2 has prompted the mobilization of a network of public health laboratories to diagnose COVID-19 patients, trace contacts and identify hot-spot areas for active community transmission at the expense of arbovirus diagnosis and control practices. | 2020-12-30 |
| 33376990 | Together, our results demonstrate that sustained sub-clinical cognitive impairments might be a common complication after recovery from COVID-19 in young adults, regardless of clinical course that were unmasked by our diagnostic approach. | 2020-12-30 |
| 33377529 | We analyzed medical records of all patients aged of 75 and older with a confirmed diagnosis of COVID-19 hospitalized in our Hospital between March 3 and April 25, 2020. | 2020-12-30 |
| 33377751 | This article provides evidence-based information and techniques to promote and foster mental and physical health for our patients and health care providers. | 2020-12-30 |
| 33377883 | Although the diagnosis establishment is done by detecting the viral ribonucleic acid (RNA) through reverse transcription-polymerase chain reaction (RT-PCR) method, CT scan has an important role in detection and treatment of COVID-19 especially in high prevalence regions. | 2020-12-30 |
| 33377885 | An array of modalities including novel techniques are being utilized as vaccine platforms, with the closest to phase III clinical trial completion being mRNA (manufactured by Moderna and BioNTech/Pfizer), inactivated virus (Sinovac, Sinopharm), viral vector (Oxford/AstraZeneca, Gamaleya, Janssen/Johnson&Johnson, CanSino), and protein subunit (Novavax). | 2020-12-30 |
| 33377948 | Of those not participating to the survey, diagnosis of domestic violence was only 0.6%(128/19,160). | 2020-12-30 |
| 33378058 | Of the 62 COVID-19 patients, 48 cases of early stage and 14 cases of advanced stage were found in the CT data of the first diagnosis. […] Among them, the CT of 14 patients with advanced stage at the first diagnosis showed multiple stage lesions (advanced stage + early stage) at the same time. […] Blood glucose is of great value in clinical diagnosis of COVID-19 and in determining the stage and prognosis of this disease. | 2020-12-30 |
| 33378060 | Data collection included demographics, previous underlying diseases, clinical manifestations, laboratory examinations, imaging examination results, diagnosis, and prognosis. | 2020-12-30 |
| 33378122 | The primary study outcome was mortality, defined as all-cause mortality or in-hospital mortality within 30 days of initial COVID-19 diagnosis. | 2020-12-30 |
| 33378275 | C-reactive protein (CRP) and computed tomography scan chest (CT-chest) had added value on COVID-19 diagnosis in suspected cases. | 2020-12-30 |
| 33378321 | This presents a unique set of challenges for diagnosis, prevention, and treatment of thrombotic complications. […] We highlight the importance of diagnosis and management of dysregulated coagulation in COVID-19 in order to improve outcomes in COVID-19 patients with thromboembolic complications. | 2020-12-30 |
| 33378344 | Every successful strategy in controlling the SARS-CoV-2 infection depends on timely diagnosis, which should include testing of asymptomatic carriers. […] Consequently, increasing the throughput for clinical laboratories for the purposes of conducting large-scale diagnostic testing is urgently needed. […] Here we support the hypothesis that standard diagnostic protocol for SARS-CoV-2 virus could be conveniently applied to pooled samples obtained from different subjects. | 2020-12-30 |
| 33378367 | Follow up was done for the participants from the first date of diagnosis to the date of recovery (negative Real-time Reverse Transcriptase Polymerase Chain Reaction (rRT-PCT) test of throat swab). | 2020-12-30 |
| 33378566 | In addition, older age (OR = 2.149, 95% CI = 1.424-3.248), diabetes (OR = 3.951, 95% CI = 2.077-7.788), cardiovascular disease (OR = 3.414, 95% CI = 1.432-8.799), nervous system disease (OR = 4.125, 95% CI = 1.252-18.681), dyspnoea (OR = 31.944, 95% CI = 18.877-92.741), achieving highest in-hospital temperature of >39.0°C (OR = 37.450, 95% CI = 7.402-683.403) and longer onset of illness to diagnosis (≥9 days) were statistically associated with higher risk of developing severe COVID-19. | 2020-12-30 |
| 33378904 | Simulations demonstrate that enlarging the testing capacity and motivating infected individuals to test for an early diagnosis may facilitate mitigating the disease spread in a relatively short time. | 2020-12-31 |
| 33379001 | Currently, reverse transcription quantitative qPCR (RT-qPCR) is used as the gold standard for diagnosis of SARS-CoV-2. […] More accurate and sensitive methods are urgently needed to support the quality assurance of the RT-qPCR or as an alternative diagnostic approach. […] To explore the feasibility of RT-dPCR in diagnostic of SARS-CoV-2, a total of 196 clinical pharyngeal swab samples from 103 suspected patients, 77 close contacts and 16 supposed convalescents were analyzed by RT-qPCR and then measured by the proposed RT-dPCR. […] The overall sensitivity, specificity and diagnostic accuracy of RT-dPCR were 91%, 100% and 93%, respectively. | 2020-12-31 |
| 33379066 | In detecting infectious diseases, such as coronavirus 2019 (COVID-19), real-time reverse-transcription polymerase chain reaction (RT-PCR) is one of the most important technologies for RNA detection and disease diagnosis. | 2020-12-31 |
| 33379092 | The COVID-19 pandemic has had a devastating impact worldwide and has brought clinical assays both for acute diagnosis and prior exposure determination to the forefront. | 2020-12-31 |
| 33380584 | There is limited information about its diagnosis, treatment and prognosis. […] COVID-19 diagnosis was confirmed with reverse transcription polymerase chain reaction method, with nasal, oral or sputum specimens. | 2020-12-31 |
| 33380736 | We furthermore tested our method in transport medium diagnostic remnant samples that previously had been tested for SARS-CoV-2, showing that our method not only correctly identified all positive samples but also substantially improved detection of the virus in low viral load samples. | 2020-12-31 |
| 33380791 | Overall, almost three quarters (71%) of the participants chose the 80-year-old patient with a diagnosis of AD to be the last to be provided with a ventilator. | 2020-12-31 |
| 33381140 | Urgent measures are needed to contain and control the virus, particularly diagnostic kits for detection and surveillance, therapeutics to reduce mortality among the severely affected, and vaccines to protect the remaining population. […] We calculate the investment required in molecular farming infrastructure that would enable us to capitalize on this technology, and provide a roadmap for the development of diagnostic reagents and biopharmaceuticals using molecular farming in plants to complement production methods based on the cultivation of microbes and mammalian cells. | 2020-12-31 |
| 33381298 | While rapid and accessible diagnosis is paramount to monitoring and reducing the spread of disease, COVID-19 testing capabilities across the U.S. remain constrained. | 2021-01-01 |
| 33381313 | Bronchoalveolar lavage (BAL) is currently not recommended in noncritically ill patients for the diagnosis of SARS-CoV-2 infection. […] Indeed, the diagnosis is based on the RT-PCR test on a nasopharyngeal swab (NPS) and abnormal findings on the chest CT scan. […] Therapeutic management was changed in 33 patients because another infectious agent was identified in 23 patients or because an alternative diagnosis was made in 10 patients. | 2020-12-31 |
| 33381691 | The groups were created according to the COVID-19 Diagnostic Guide of Ministry of Health: A: outpatients with suspected COVID-19, B: inpatients for follow-up and treatment, C: patients treated in intensive care unit (ICU). […] The diagnostic accuracy of UFT was detected in all group, the pooled sensitivity was 92% (95% CI: 87-95%) and specificity was 89% (95% CI: 80-98%). […] The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. | 2020-12-31 |
| 33381779 | The median duration of acute infection was 19 days; one patient remained reverse transcription polymerase chain reaction (RT-PCR) positive >11 weeks from diagnosis. | 2020-12-31 |
| 33381929 | Thus, the diagnosis of COVID-19 requires specific viral RNA testing. | 2020-12-31 |
| 33382639 | Statistics included bivariate and multivariate techniques. | 2020-12-31 |
| 33382773 | We conducted a retrospective study on patients admitted to the ICU with a diagnosis of COVID-19 between March 10 (i.e. the date of the first admitted patients) and April 30, 2020. | 2020-12-31 |
| 33382826 | Among those hospitalized, the fully adjusted OR for getting into intensive care or expiring was 5.18 (1.29, 20.72) when based on plasma samples obtained at the time of diagnosis or up to one week before. | 2020-12-31 |
| 33382912 | Low ADAMTS13 activity confirmed the diagnosis of thrombotic thrombocytopenic purpura (TTP). | 2020-12-31 |
| 33383171 | The hallmark is elevated troponin, which occurs in 36% of COVID patients, with electrocardiogram, echocardiogram, and cardiac magnetic resonance being valuable tools to assist in diagnosis. | 2020-12-31 |
| 33383210 | Proper detection using sensitive and precise NAT kits is essential to guarantee diagnosis. | 2020-12-31 |
| 33383219 | The pathologist is involved in many diagnostic steps together with the clinical infectious disease team in the management of COVID-19-affected patients. | 2020-12-31 |
| 33383223 | Aside from the outbreak of the coronavirus disease 2019 (COVID-19), serological tests are not well known for their diagnostic value. | 2020-12-31 |
| 33383396 | As breathing relaxation techniques can improve sleep quality, anxiety, and depression, the current study aimed to evaluate the effectiveness of diaphragmatic breathing relaxation training (DBRT) for improving sleep quality among nurses in Wuhan, China during the COVID-19 outbreak. | 2020-12-31 |
| 33383438 | The diagnosis of AKI was based on the KDIGO criteria. | 2020-12-31 |
| 33383888 | Diagnostic tests have been considered as the main alternative for the control of coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as a correct diagnosis allows for decision making when facing the disease, particularly as there is a lack of effective therapeutic protocols and vaccines. […] Thus, in this review, we summarized the main diagnostic approaches currently available for the diagnosis of SARS-CoV-2 infection in humans based on studies available in article databases. […] The studies have shown that the performance of diagnostic methods depends on different factors, such as the type of samples and the characteristics of each assay. […] Thus, the COVID-19 pandemic has highlighted the critical role of diagnostic technologies in the control of infectious diseases. | 2021-01-01 |
| 33384403 | The hemorrhagic form of cerebral venous thrombosis can be a diagnostic challenge and is treated by anticoagulation therapy, despite the existence of an intracerebral hemorrhage. | 2021-01-01 |
| 33385250 | The finding revealing that olfactory dysfunction was the first symptom in 40% of the patients suggests the importance of inquiry on olfactory functions for the early diagnosis of the disease. | 2021-01-01 |
| 33385524 | Remotely monitored physiologic sensors on implantable cardiac devices can provide insight into the differential diagnosis of dyspnea in the heart failure population. | 2021-01-01 |
| 33385640 | Data for all patients admitted to seven community hospitals in Michigan, United States, with polymerase chain reaction confirmed diagnosis of COVID-19 from March 10 to April 15, 2020 were analyzed. | 2021-01-01 |
| 33385714 | In this regard, different multiple sequence alignment techniques are used to align the SARS-CoV-2 genomes separately. […] Subsequently, consensus conserved regions are identified after finding the conserved regions from each aligned result of alignment techniques. | 2021-01-01 |
| 33385765 | Qualitative detection of total (IgG + IgM) anti-SARS-CoV-2 antibody was performed using electrochemiluminescence immunoassay in plasma samples collected at least 14 days post-polymerase chain reaction (PCR) confirmation of diagnosis. at admission of 8.3 ± 1.0%. […] Anti-SARS-CoV-2 antibody was estimated at a median of 16 (14-17) days post-PCR confirmation of COVID-19 diagnosis. […] COVID-19 patients with T2DM may not undergo seroconversion even after two weeks of diagnosis. | 2021-01-01 |
| 33385779 | Depressive and anxiety symptoms appear to be predictors of sleep quality regardless of any pre-existing diagnosis. […] This study shed new light on how the COVID-19 pandemic might affect the sleep behaviors of young adults without a pre-existing mental health diagnosis. | 2021-01-01 |
| 33387046 | Graft delamination is primarily an imaging diagnosis and is confirmed with the help of ultrasound which shows the separation of graft fabric layers. […] The diagnosis was established on ultrasonography which revealed separation of the graft fabric layers with thrombosis within the “false” and “true” lumen of the graft. | 2021-01-02 |
| 33387222 | After diagnosis, median time to death was 7 days in the 14 patients who died, with a range between 4 and 18 days. | 2021-01-02 |
| 33387306 | Alternative tools are needed that can help in diagnosis of the coronavirus. […] Researchers of this article investigated the potential of machine learning methods for automatic diagnosis of corona virus with high accuracy from X-ray images. | 2021-01-02 |
| 33387345 | A Sequential Organ Failure Assessment (SOFA) score at AKI diagnosis of 8 or higher was associated with RRT, OR 5.2, p 0.032. […] At the time of AKI diagnosis, patients had a worse liver profile and higher inflammation markers than at admission. | 2021-01-02 |
| 33387453 | Cancer patients who did not receive anticancer treatment and clinical or radiological diagnosis of COVID-19 without a positive reverse transcription-polymerase chain reaction (RT-PCR) test were excluded. | 2021-01-02 |
| 33387553 | These results highlight the importance of endodontic diagnosis and treatment in the provision of emergency dental care during a pandemic, and demonstrates that dental treatment can be provided in a manner that minimizes the risk of viral transmission, maintaining continuity of care for a large patient population. | 2021-01-02 |
| 33387561 | The gold standard method in the diagnosis of SARS-CoV-2 infection is the detection of viral RNA in the nasopharyngeal sample by RT-PCR. | 2021-01-02 |
| 33388003 | These advantages comes with limitations, some of them include a limited physical exam, lack of access to diagnostic testing or imaging, and many other pitfalls and persistent unmet needs. | 2021-01-03 |
| 33388247 | More specifically, we observed a reduction of hospitalizations for new diagnosis (from n = 44 to n = 27) and endoscopic re-evaluations (from n = 46 to n = 8). | 2021-01-03 |
| 33389111 | The mean interval between the diagnosis of maternal COVID-19 infection and the delivery was 8.5 days. | 2021-01-03 |
| 33389315 | Emerging studies in patients with COVID-19 are suggesting a key role of monocytes/macrophages in the pathogenesis of this viral infection, and there is a significant overlap between several features reported in severe COVID-19 and the features included in the HLH-2004 diagnostic criteria. […] Because HLH is a multi-organ syndrome, the diagnostic approach in a patient with severe COVID-19 in whom HLH is suspected must be carried out in a syndromic and holistic way, and not in the light of isolated clinical or laboratory features. […] In COVID-19 patients presenting with persistent high fever, progressive pancytopenia, and hepatosplenic involvement, together with the characteristic triad of laboratory abnormalities (hyperferritinaemia, hypertriglyceridaemia, and hypofibrinogenaemia), the suspicion of HLH is high, and the diagnostic workup must be completed with specific immunological and histopathological studies. | 2021-01-03 |
| 33389359 | LA-GSA+ (optimal cut-off ≤ 9.1%, AUC 0.95) showed the highest diagnostic performance. | 2021-01-03 |
| 33389368 | The participants stated that they could not continue routine interventional diagnosis and treatment practices during the outbreak. […] For this reason, 14.9% of physicians said to missed the diagnosis in this process. | 2021-01-03 |
| 33389439 | Participants were selected using convenience and snowball sampling techniques. | 2021-01-03 |
| 33389499 | In this review, we summarized SARS-CoV-2 laboratory diagnostic schemes, pathophysiological indices of tissues and organs of COVID-19 patients, and laboratory diagnostic strategies for distinct disease stages. | 2021-01-03 |
| 33389519 | On day 8 laboratory tests confirmed the diagnosis of acquired TTP. | 2021-01-03 |
| 33389959 | It is important to establish proactive care and screening tests for diabetic patients suspected with COVID-19 for timely disease diagnosis and management. | 2021-01-04 |
| 33390088 | AI techniques can significantly improve treatment consistency and decision making by developing useful algorithms. | 2021-01-04 |
| 33390432 | Of 212 cases, which included 13 confirmed COVID-19 cases in the diagnostic cohort, exposure to COVID-19 cases (P<0.0001) and chest CT bGGO (P=0.0022) were identified as significant predictors of COVID-19. | 2021-01-04 |
| 33390566 | Besides the direct effects of COVID-19 on mortality, collateral impacts on diagnosis and management of acute febrile illnesses (AFI) is a matter of great concern. | 2021-01-04 |
| 33390662 | Early diagnosis of the virus is of great significance for both of infected patients and doctors providing treatments. […] Chest Computerized tomography (CT) screening is one of the most straightforward techniques to detect pneumonia which was caused by the virus and thus to make the diagnosis. | 2021-01-04 |
| 33390676 | Viral lysis buffer maintains the integrity of SARS-CoV-2 RNA for up to 48 hours even at room temperature and supports delayed diagnosis with an overwhelming sample load in testing laboratories. | 2021-01-04 |
| 33391394 | Histopathology departments have adapted to the challenges posed by the COVID-19 pandemic by a variety of changes including working pattern alterations, technology adoptions and incorporation of techniques. | 2021-01-04 |
| 33391734 | Diagnosis of FD should not preclude providing full therapeutic and organ support as needed for patients with FD and severe or critical COVID-19, although a FD-specific safety profile review should always be conducted prior to initiating COVID-19-specific therapies. | 2021-01-04 |
| 33391769 | It also highlights some of the challenges associated with diagnosis and care of patients with rare diseases such as sCJD, and how these have been intensified by COVID-19. | 2021-01-04 |
| 33392037 | With the global outbreak of coronavirus disease 2019 (COVID-19), chest computed tomography (CT) is vital for diagnosis and follow-up. […] All images were subjectively evaluated by 2 radiologists to determine whether the nodules were detectable and if the overall image quality met diagnostic requirements. | 2021-01-04 |
| 33392306 | Understanding a virus shedding patterns in body fluids/secretions is important to determine the samples to be used for diagnosis and to formulate infection control measures. | 2021-01-04 |
| 33392388 | Due to the limitation of test kits and the need for screening and rapid diagnosis of patients, it is essential to perform a self-operating detection model as a fast recognition system to detect COVID-19 infection and prevent the spread among the people. | 2021-01-04 |
| 33392511 | We envisage there will be many more such presentations of acute COVID-19-associated cardiogenic shock and we recommend clinicians consider this diagnosis when presented with an acutely unwell patient with an unclear diagnosis following a viral illness. | 2021-01-04 |
| 33392516 | Outcomes were assessed within 30 days of COVID-19 diagnosis, including hospitalisation, intensive care unit admission, invasive mechanical ventilation, renal failure, and death. | 2021-01-04 |
| 33392545 | Secretion management techniques include nebulized bronchodilators, chest percussion/drainage techniques, manually assisted coughing techniques, nasotracheal suctioning, and mechanical insufflation-exsufflation. […] ED professionals, including respiratory therapists, should be familiar with the significant comorbidities associated with SCI/D and the customized secretion management procedures and techniques required for optimal medical management and prevention of respiratory failure. | 2021-01-04 |
| 33392568 | This cross-sectional survey was developed using the Life Events Checklist for Diagnostic and Statistical Manual of Mental Disorders, 5th Edition: DSM-5 (DSM-5) and the PTSD Checklist for DSM-5 (PCL-5). | 2021-01-04 |
| 33393066 | CRISPR gene-editing technology has the potential to transform the diagnosis and treatment of infectious diseases, but most clinicians are unaware of its broad applicability. […] We searched Pubmed and Google Scholar for CRISPR-based strategies in the diagnosis and treatment of infectious diseases. […] CRISPR technologies can be harnessed to create rapid, low-cost diagnostic systems, as well as to identify drug-resistance genes. | 2021-01-04 |
| 33393315 | This review is focused on discussion and critical evaluation of instrumental tools for COVID-19 diagnosis that were developed in the last months. […] The global epidemic pointed at the necessity to introduce sensitive methods for instrumental diagnosis of COVID-19 and distinguishing it from the other viral diseases. | 2021-01-04 |
| 33393319 | The diagnosis of all patients included in the study was made according to the WHO interim guideline. | 2021-01-04 |
| 33393672 | Our findings demonstrate that random saliva is an alternative diagnostic specimen for the detection of SARS-CoV-2. | 2021-01-04 |
| 33393750 | All responses were anonymous and results were analyzed with standard statistical techniques. 176 surveys were returned and 164 were entirely completed. | 2021-01-04 |
| 33393790 | We believe that the early detection and characterization of coinfections by using metaproteomics from COVID-19 patients will potentially impact the diagnosis and treatment of patients affected by SARS-CoV-2 infection. | 2021-01-04 |
| 33394078 | In order to effectively control the source of infection, cut off the transmission route, protect the susceptible population, ensure the medical quality and medical safety, perform epidemic prevention and control, and comprehensively guarantee the life safety and physical health of medical staff, patients, and family members, it is very important to organize and carry out nuclear medicine diagnosis and treatment scientifically and safely. | 2021-01-04 |
| 33394096 | In this retrospective study, we searched our clinical database between March 1st, 2020 and May 22nd, 2020 to identify patients who had positive real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat swabs for COVID-19, had availability of clinical, laboratory information and had availability of CT scan of chest or abdominal radiograph, abdominal ultrasound or CT scan within 2 weeks of the diagnosis. | 2021-01-04 |
| 33394125 | Health care workers who come into contact with the upper aero-digestive tract during diagnostic and therapeutic procedures, such as otolaryngologists, oral and maxillofacial surgeons, and head and neck surgeons, may undergo profound changes in their activities and are particularly at risk. | 2021-01-04 |
| 33394144 | To contain this pandemic, collaborative approach involving accurate diagnosis, epidemiology, surveillance, and prophylaxis is essential. […] However, proper diagnosis using rapid technologies plays a crucial role. […] To address these challenges, several POC assays have been developed to facilitate the COVID-19 diagnosis outside the centralized testing laboratories as well to accelerate the clinical decision making with a least turnaround time. […] Hence, in this report, we review different nucleic acid-based and serological techniques available for the diagnosis and effective prevention of COVID-19. […] KEY POINTS : • Provides comprehensive information on the different diagnostic tools available for COVID-19 • Nucleic acid based tests or antigen detection tests are used for diagnostic purpose • Accurate diagnosis is essential for the efficient management of COVID-19. | 2021-01-04 |
| 33394194 | Patients admitted to our center with the diagnosis of ischemic and hemorrhagic stroke, between March 1, 2019, Jun 1, 2019, and the similar 3-month period in 2020 (COVID-19 pandemic period), were compared in terms of clinical characteristics and outcome. | 2021-01-04 |
| 33394281 | The study included 609 consecutive adult patients (male: 54.52%, mean age: 59.23 ± 15.55 years) hospitalized with the diagnosis of COVID-19 in a tertiary level hospital. | 2021-01-04 |
| 33394313 | The following paper aimed to present the most crucial aspects of SARS-CoV-2 infection from the point of view of forensic experts and pathologists, recommendations and safety precautions regarding autopsies, autopsy room requirements, possible techniques, examinations used for effective viral detection, recommendations regarding burials, and gross and microscopic pathological findings of the deceased who died due to SARS-CoV-2 infection. | 2021-01-04 |
| 33394354 | The ASA score, severity of peritonitis, qSOFA score, diagnosis other than appendicitis, and COVID period resulted independent predictors of complications. | 2021-01-04 |
| 33394364 | GGO, CO, RNO and a peripheric, diffuse and basal prevalence showed good correlation with COVID-19 diagnosis. […] A logistic regression analysis pointed out GGO and a basal or diffuse distribution as independent predictors of COVID-19 diagnosis. […] GGO and others CXR findings showed a good correlation with COVID-19 diagnosis; besides GGO a diffuse or bibasal distribution resulted in independent variables highly suggestive for COVID-19 infection thus enabling radiologists to signal to clinicians radiologically suspect patients during the pandemic descending phase. | 2021-01-04 |
| 33394522 | A low awareness of the allergenic potential of PEG among consumers, manufacturers and doctors leads to under-diagnosis and under-reporting of allergy to PEGs, putting patients at risk of repeated severe reactions. […] To investigate clinical manifestations, time to diagnosis and impact of a PEG allergy diagnosis on the daily life of patients diagnosed with allergy to PEG from 2010 to 2019. […] Detailed clinical history was obtained, and allergy investigations had been performed at the time of diagnosis. […] All patients were contacted and asked to retrospectively complete a questionnaire about causes and impact on daily life of an allergy to PEG, scored on a likert scale (0-10) before and after diagnosis. […] Seven patients reported repeated reactions before diagnosis (median 3, range 2-6). […] Median time from first reaction to diagnosis was 20 months (range 2-120). […] None of the patients experienced severe allergic reactions after the diagnosis. […] Median likert score of the impact on daily life before diagnosis was 7 compared with 4 after diagnosis. […] Improved awareness about the clinical presentation and common culprits, clear product labelling and a standardized nomenclature is needed to ensure the timely diagnosis of PEG allergy to prevent repeated anaphylactic reactions with severe impact on patients’ lives. | 2021-01-04 |
| 33394709 | Laboratory testing, echocardiography, cardiac magnetic resonance imaging, and even endomyocardial biopsy may be needed for timely diagnosis. […] Future research is needed to understand the true prevalence of COVID-19 myocarditis, as well as to better define various diagnostic protocols and treatment strategies. | 2021-01-04 |
| 33394823 | A 38-question web-based survey was distributed to site principal investigators of the Critical Care EEG Monitoring Research Consortium, and institutional contacts for the Neurodiagnostic Credentialing and Accreditation Board. | 2021-01-04 |
| 33394922 | The diagnosis of these cutaneous changes may be challenging and resemble other cutaneous conditions. | 2021-01-04 |
| 33394951 | The most common medical diagnosis was respiratory compromise, and the most common surgical diagnosis was appendicitis. | 2021-01-04 |
| 33394992 | Donors with a previous diagnosis of COVID-19 were accepted after documenting 2 negative PCR tests with complete symptom resolution for at least 28 days and significant social distancing for 14 days prior to surgery. | 2021-01-04 |
| 33395240 | Among respondents, 59% reported that the use of telemedicine helps expedite diagnosis and treatment more than seeing patients in person in the clinic, 55% of respondents managed urgent issues by telemedicine, 80% believed that patients benefited From urgent assessment by telemedicine, and 57% believed an emergency department visit or a hospitalization was avoided because of a telemedicine visit. | 2021-01-04 |
| 33395304 | This RdRP detection method can provide a new route for rapid diagnosis of RNA virus-infected patients. | 2021-01-04 |
| 33395398 | The patients’ gender, age, residence, primary diagnosis, drug classification, weekly number of prescriptions, and prescribed drugs were analyzed. | 2021-01-04 |
| 33395576 | To better understand the relative performance characteristics of saliva and upper airway samples, I performed a rapid systematic review (registered on PROSPERO as CRD42020205035), focusing on studies that included at least 20 subjects who provided diagnostic saliva and upper airway samples on the same day, which were tested by nucleic acid amplification methods and for which a confusion matrix could be constructed for based on a composite reference standard. […] Seven of these cohorts were incorporated into a meta-analysis using a random effects model, which suggests that nasopharyngeal swabs are somewhat more sensitive than saliva samples for the diagnosis of early disease in ambulatory patients, such as in drive-through centers or community health centers. | 2021-01-04 |
| 33395698 | A positive result of SARS-CoV-2 nucleic acid detection provides critical laboratory evidence for clinical confirmed diagnosis, pandemic status evaluation, a pandemic prevention plan, treatment of infected people with symptoms, and protection of uninfected people. | 2021-01-04 |
| 33396557 | Affording complexity for superior fitness and camouflage, SARS-CoV-2 challenges diagnosis and vaccine vigilance. | 2021-01-05 |
| 33396587 | Diagnostic performance was assessed by the area under the receiver operating characteristic curve (AUC). […] Thus, providing rapid accurate diagnosis in patients suspected of COVID-19 infection, facilitating the timely implementation of isolation procedures and early intervention. | 2021-01-05 |
| 33396792 | Currently, different types of diagnostic testing have been adopted globally, such as nucleic acid detection tests, immunological tests and imaging approaches; however, real-time reverse transcriptase-polymerase chain reaction (RT-PCR) remains the “gold standard” for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). | 2021-01-05 |
| 33397246 | Different diagnostic laboratory tests have been used to detect the infection. […] Each diagnostic tool, such as Chest Computed tomography (CT) imaging, genome sequencing, nucleic acid amplification methods, whole genome sequencing, microarray, and serology testing have several advantages and disadvantages. […] Nucleic acid amplification methods are better diagnostic tools for the detection of SARS-CoV-2 in early stages of the infection, while serological tests are more appropriate for the recognition of previously infected patients. […] In this review, we will briefly consider each diagnostic method, and discuss its pros and cons. | 2021-01-05 |
| 33397344 | Indirect questioning techniques with higher levels of confidentiality seem helpful in obtaining more realistic estimates of the degree to which people follow the recommended personal hygiene measures. | 2021-01-05 |
| 33397457 | Patients with confirmed COVID-19 diagnosis (defined as SARS-CoV-2 PCR positive nasopharyngeal swab) will be recruited from four participating isolation and treatment centres in Nigeria: two secondary care facilities (Infectious Diseases Hospital, Olodo, Ibadan, Oyo State and Specialist State Hospital, Asubiaro, Osogbo, Osun State) and two tertiary care facilities (Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Osun State and Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State). […] The model was implemented in REDCap and includes stratification by age, gender, viral load at diagnosis and presence of relevant comorbidities. | 2021-01-05 |
| 33397587 | This POCT detected SARS-CoV-2 antigen in saliva and would be useful for COVID-19 diagnosis. | 2021-01-05 |
| 33397593 | Delays in diagnosis and treatment initiation may have an impact on the extent of the primary lesion as well as the cancer-specific survival because of the development and progression of inguinal lymph node metastases. […] The international consensus panel proposed a framework for the diagnostic and invasive therapeutic procedures for penile cancer within a low-risk environment for COVID-19. | 2021-01-05 |
| 33397753 | There have been many advances in diagnostic methods for SARS-CoV-2 and therapies for hospitalized patients nationwide. | 2021-01-05 |
| 33397829 | These findings suggest that the qPCR assay with the ddPCR defined reference materials could be used as a highly sensitive and compatible diagnostic method for viral RNA detection. | 2021-01-05 |
| 33397872 | As positive CT findings were more prominent in symptomatic and co-morbid patients HRCT chest in COVID-19 patient had a major diagnostic and prognostic importance. | 2021-01-05 |
| 33397903 | The current practice for diagnosis of COVID-19, based on SARS-CoV-2 PCR testing of pharyngeal or respiratory specimens in a symptomatic patient at high epidemiologic risk, likely underestimates the true prevalence of infection. […] This array can be used as a diagnostic tool, as an epidemiologic tool to more accurately estimate the disease burden of COVID-19, and as a research tool to correlate antibody responses with clinical outcomes. | 2021-01-05 |
| 33397956 | High quality serology is key to avoiding medically costly diagnostic errors, as well as to assuring properly informed public health decisions. | 2021-01-05 |
| 33398013 | Effective screening of SARS-CoV-2 enables quick and efficient diagnosis of COVID-19 and can mitigate the burden on healthcare systems. | 2021-01-05 |
| 33398067 | The diagnostic test sensitivity of COVID-19 is limited due to irregularities in specimen handling. […] We propose a deep learning framework that identifies COVID-19 from medical images as an auxiliary testing method to improve diagnostic sensitivity. […] The proposed method represents a potential computer-aided diagnosis method for COVID-19 in clinical practice. | 2021-01-05 |
| 33398232 | This study aimed to share our experiences during the coronavirus disease 2019 (COVID-19) pandemic obtained in diagnostic radiology facilities of five Training Research Hospitals in the Asian part of Istanbul (North Hospitals). […] As the corporate radiology team serving in these designated pandemic hospitals, examination details and safety procedures of some diagnostic radiology facilities among five training research hospitals have been identified in the current study. […] Our guidelines and preparedness protocol aimed to reduce patient morbidity and infection-related mortality through quick and proper diagnosis to prevent the spread of COVID-19 to our employees, patients and the general public during the COVID-19 pandemic. […] Technical details of recent investigation can provide useful information about the management of diagnostic radiology departments during the fight with the COVID-19 pandemic in cities with high population density such as Istanbul. | 2021-01-05 |
| 33398233 | This review provides a current status of the COVID-19, epidemiology, an overview of phylogeny, mode of action, diagnosis, and possible treatment methods and vaccines. | 2021-01-05 |
| 33398237 | From the 1918 influenza pandemic (H1N1) until the recent 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, no efficient diagnostic tools have been developed for sensitive identification of viral pathogens. | 2021-01-05 |
| 33398256 | The cornerstones of this approach include the fundamental principles of management of infantile spasms, decentralization of patient care to local health providers, efforts for improving sensitivity and specificity of diagnosis, early initiation of first-line therapeutic options, and constant motivation of parents and local health providers to be vigilant for therapeutic response, adverse effects of therapy, and infections. | 2021-01-05 |
| 33398711 | For each X-ray, participants were asked to choose the most likely diagnosis, and to grade the degree of self-confidence regarding the accuracy of their answer in a score from 0 (not confident) to 10 (very confident). | 2021-01-05 |
| 33399086 | This study evaluated the consequences in Europe of the COVID-19 outbreak on pathology laboratories orientated toward the diagnosis of thoracic diseases. | 2021-01-05 |
| 33399137 | Using synthetic SARS-CoV-2 samples and RNA extracts from patients, we demonstrate that colorimetric LAMP is a quantitative method comparable in diagnostic performance to RT-qPCR (i.e., sensitivity of 92.85% and specificity of 81.25% in a set of 44 RNA extracts from patients analyzed in a hospital setting). | 2021-01-05 |
| 33399180 | Difficulty in reaching the correct diagnosis due to the lack of physical examination was one of the disadvantages that faced the participants. | 2021-01-05 |
| 33399743 | This article highlights the importance of an early diagnosis of gastrointestinal and hepatic manifestations, increase the index of suspicion, make a timely diagnosis, and recognize eventual complications of the disease. | 2021-01-05 |
| 33399763 | In this document, a team of international specialists in interventional pulmonology elaborated a series of recommendations, based on the available evidence to define the risk stratification, diagnostic methods and technical considerations on procedures such as bronchoscopy, tracheostomy, and pleural procedures among others. | 2021-01-05 |
| 33399877 | Half of the patients with an abdominal ultrasound and/or CT scan had signs of severity at diagnosis, four times higher than the previous year. | 2021-01-05 |
| 33400058 | The developments of nanoparticle-based therapeutic and diagnostic approaches have been also discussed for COVID-19. | 2021-01-05 |
| 33400067 | During SARS-CoV2 pandemic, Italian physicians were forced to work with less instrumental diagnostic resources, relying on their clinical knowledge mostly. […] The aim of this case report is to highlight the importance of performing a precise neurological evaluation, particularly during these challenging times: it might avoid incorrect diagnosis and favour the discovery of rare clinical diseases. | 2021-01-05 |
| 33400417 | Early identification, diagnosis, and management through a multidisciplinary approach can facilitate safe disease resolution for patients. | 2021-01-05 |
| 33400680 | We also noted the most frequent billing codes used based on the time spent in the patient care and the number of clinical tasks (eg, activity suggested through diagnosis or procedural code) that were addressed remotely by the physicians. | 2021-01-05 |
| 33400682 | Coupled with a meta-analysis and natural language processing techniques, the emotion polarity of individual opinions was examined in their given context. | 2021-01-05 |
| 33400771 | Diagnosis of major bleeding was registered in 0.5% (47/9,460) of all SARS-CoV-2 positive individuals and in 2.3% of those hospitalized. | 2021-01-05 |
| 33401144 | Transcription factors (TFs) served as essential DNA binding proteins play an integral role in regulating cytokine storm, and the detection of it in the human coronavirus environment provides especially valuable approaches to diagnosis and treatment of 2019-nCoV and development of antiviral drugs. | 2021-01-05 |
| 33401205 | A large number of patients present atypical symptoms, which represent a big challenge for early diagnosis and prompt infection source isolation. […] Currently, COVID-19 diagnosis predominantly depends on nucleic acid tests (NAT) for SARS-CoV-2 in respiratory specimens, but this method presents a high rate of false negative results. […] Therefore, serum antibody measurement has been rapidly developed as a supplementary method with the aim of improving diagnostic accuracy. | 2021-01-05 |
| 33401340 | Qualitative research was undertaken, using an empirical approach and inductive content analysis techniques. | 2021-01-05 |
| 33401392 | With over 43 million cases and 1.1 million deaths recorded worldwide, accurate and rapid diagnosis continues to be a cornerstone of pandemic control. […] In this review, we aim to present an objective overview of the latest nucleic acid-based diagnostic tests for the detection of SARS-CoV-2 that have been authorized by the Food and Drug Administration (FDA) under emergency use authorization (EUA) as of 31 October 2020. […] We systematically summarize and compare the principles, technologies, protocols and performance characteristics of amplification- and sequencing-based tests that have become alternatives to the CDC 2019-nCoV Real-Time RT-PCR Diagnostic Panel. | 2021-01-06 |
| 33401657 | This study provides evidence for SARS-CoV-2 infection in the human nervous system, digestive system, reproductive system, respiratory system, circulatory system, and urinary system using scRNA-seq data, which helps in the clinical diagnosis and treatment of patients. | 2021-01-06 |
| 33401683 | A total of 225 healthcare workers from hospitals, medical centres and diagnostic units completed a set of questionnaires during the first few months of the COVID-19 lockdown period (March-May 2020). | 2021-01-06 |
| 33402136 | 72.8% were satisfied with the depth of discussion in virtual MDTs and 83.3% felt that the decision-making in diagnosis had not changed following the switch from face-to-face MDTs. | 2021-01-06 |
| 33402334 | We provide an overview of the impact of the ongoing COVID-19 pandemic on hepatitis B virus (HBV) programmes globally, focusing on the possible consequences for prevention, diagnosis and treatment. | 2021-01-06 |
| 33402392 | Current smokers were more likely to report symptoms suggesting a diagnosis of COVID-19; classic symptoms adjusted OR (95% CI) 1.14 (1.10 to 1.18); >5 symptoms 1.29 (1.26 to 1.31); >10 symptoms 1.50 (1.42 to 1.58). | 2021-01-06 |
| 33402443 | Characteristics potentially associated with anxiety, self-isolation and medication adherence (gender/age/diagnosis/education/work status/comorbidity/DMARD/smoking/EQ-5D/disease activity) were explored with multivariable logistic regression analyses. | 2021-01-06 |
| 33402610 | Computed tomography (CT) of the chest plays an important role in the diagnosis and management of coronavirus disease 2019 (COVID-19), but it should not be used indiscriminately. […] In conclusion, though CT chest is an indispensable diagnostic tool in COVID-19, it should be used judiciously and only when specifically indicated. | 2021-01-06 |
| 33402754 | We estimated the number of new cases, diagnostic tests required, and the number of available hospital and intensive care unit (ICU) beds (with and without ventilators) for each scenario. if all restrictions were to be lifted and the infection growth rate increased to 10%. | 2021-01-06 |
| 33403166 | The report highlights the importance of differential diagnosis of TB in COVID-19 patients as well as the consideration of TB in a patient with peripheral neuropathy after nutritional causes have been ruled out. | 2021-01-06 |
| 33403178 | Subsequently, four of the five patients tested positive for COVID-19, and one of them was presumed to have the diagnosis based on clinical and imaging findings. | 2021-01-06 |
| 33403179 | Significant factors in the conservatively managed group included lack of tension physiology, the smaller size of pneumothorax, lack of underlying diabetes, presence of pneumomediastinum, and not being on mechanical ventilation during diagnosis. | 2021-01-06 |
| 33403980 | Specific recommendations for parasite and vector surveillance, diagnosis, case management, mosquito vector control and community outreach and sensitisation are given. | 2021-01-06 |
| 33403997 | ‘Long-COVID’ or ‘COVID long-haulers’ generally describes those persons with COVID-19 who experience symptoms for >28 days after diagnosis, whether laboratory confirmed or clinical. | 2021-01-06 |
| 33403998 | Early diagnosis of malaria by either a rapid diagnostic test or microscopy enables prompt treatment with the effective antimalarial, artemether-lumefantrine, preventing progression to severe disease and death. | 2021-01-06 |
| 33404079 | They were tested within 3 days of diagnosis and 28 to 169 days after infection. | 2021-01-06 |
| 33404147 | After the dermatological examinations, the diagnosis and management of the diseases, and classification of diseases according to lesion locations were recorded. | 2021-01-06 |
| 33404516 | Currently, there is a lack of comprehensive understanding in various biomedical features and appropriate analytical approaches for enabling the early detection and effective diagnosis of patients with COVID-19. […] Our findings, which come from a relatively large sample size, and analytical workflow will supplement and assist with clinical decision support for current COVID-19 diagnostic methods and other clinical applications with high-dimensional multimodal biomedical features. | 2021-01-06 |
| 33404786 | Elucidating the distinguishing radiographic features of MIS-C may help refine the case definition and expedite diagnosis and treatment. | 2021-01-06 |
| 33404890 | Telemedicine, which is used to deliver health care services using information or communication technology, provides an opportunity to carry out the evaluation, diagnosis, and even monitor the patients after discharge when social distancing is needed [15]. | 2021-01-06 |
| 33405001 | Observational studies suggest that a heart failure (HF) diagnosis carries a poor prognosis in subjects with severe SARS-CoV2 (COVID-19) infection, but it is unknown whether this association reflects direct myocardial damage due to COVID-19 or the consequence of preexisting cardiac defects and related cardiovascular disease (CVD) risk burden. […] Therefore, a specific algorithm focused on diagnostic differentiation in acute patients distinguishing between acute HF and acute respiratory distress syndrome related to COVID-19 is needed. […] Further, several concerns exist for the management of patients with an uncertain diagnosis and acute dyspnea, the exact relationship existing between COVID-19 and HF. | 2021-01-06 |
| 33405302 | We retrospectively reviewed electronic medical records of 552 patients who were evaluated by a Henry Ford Health System dermatologist between February 2020 and September 2020 and had a diagnosis of COVID-19 infection. | 2021-01-06 |
| 33405338 | Differentiating COVID-19 from other acute illnesses will require widespread diagnostic testing, especially during influenza seasons. | 2021-01-06 |
| 33405402 | The clinical differential diagnosis was viral rash, acute generalized exanthematous pustulosis (AGEP), or multiform erythema. computed tomography with a diagnosis of interstitial pneumonia and a respiratory tract sample positive for SARS-CoV-2 in a reverse transcriptase polymerase chain reaction assay. | 2021-01-06 |
| 33406052 | During the ongoing COVID-19 outbreak, mHealth can assist with health promotion, directions for medication use, and disease diagnosis via online chat and video consultation without contacting others. | 2021-01-06 |
| 33406053 | A time-correlated Bayesian approach called Nowcasting by Bayesian Smoothing (NobBS) was applied in real time to line lists of reportable disease surveillance data, accounting for the delay from diagnosis to reporting and the shape of the epidemic curve. | 2021-01-06 |
| 33406112 | Rapid diagnosis is an important intervention in managing the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outbreak. | 2021-01-06 |
| 33406122 | Presence of immunoglobulin G (IgG) antibody specific to SARS-CoV-2 nucleoprotein was detected using a chemiluminescent microparticle immunoassay in samples from 7,370 patients, without previous history of COVID-19 diagnosis, suspected of having either Dengue (n = 1,700) or Chikungunya (n = 7,349) from December 1st, 2019 to June 30th, 2020. […] Our findings demonstrate that concomitant Dengue or Chikungunya outbreaks may difficult the diagnosis of SARS-CoV-2 infections. […] Data presented here demonstrate that in arboviral endemic regions, SARS-CoV-2 infection must be always considered, regardless of the existence of a previous positive diagnosis for Dengue or Chikungunya. | 2021-01-06 |
| 33406478 | Real-time polymerase chain reaction using nasopharyngeal swabs is currently the most widely used diagnostic test for SARS-CoV-2 detection. […] We also found an association between correct nasopharyngeal swab techniques and recency of video publication date (relative to May 15, 2020). | 2021-01-06 |
| 33406644 | Massive molecular testing for SARS-CoV-2 diagnosis is mandatory to manage the spread of COVID-19. […] Diagnostic screening should be performed at a mass scale, extended to the asymptomatic population, and repeated over time. […] An accurate diagnostic pipeline for SARS-CoV-2 that could massively increase the laboratory efficiency, while being sustainable in terms of time and costs, should be based on a pooling strategy. | 2021-01-07 |
| 33406788 | For this reason, the aim is to automate the process of diagnosis and treatment. | 2021-01-07 |
| 33406872 | Purpose was to analyze the impact of COVID-19 pandemic in stroke care and to evaluate stroke outcomes according to the diagnosis of COVID-19. | 2021-01-07 |
| 33407347 | The primary endpoint was a diagnosis of COVID-19 between January 1st and June 4th, 2020; the secondary endpoint was hospital mortality of patients with COVID-19. | 2021-01-07 |
| 33407578 | An appropriate diagnostic screening for thrombotic complications and the early treatment recommendations of antithrombotic drugs could represent an important topic even in asymptomatic individuals. | 2021-01-07 |
| 33407750 | A total of 11,894 prehospital records were included, of which 481 had a primary hospital diagnosis code related to-, or positive test results for Covid-19. | 2021-01-07 |
| 33407911 | Proper diagnosis can increase the likelihood of appropriate and timely antibiotic treatment, identify potential clusters of disease, and facilitate source attribution. | 2021-01-07 |
| 33408084 | Unbiased multivariate logistic regression analysis was performed to determine variables that were independently and significantly associated with increased risk of death and/or intensive care unit (ICU) admission within 30 days of COVID-19 diagnosis. 62% of patients in our cohort were of non-white ethnic background and the prevalence of diabetes was 38%. 323 (36%) patients met the primary outcome of death/admission to the ICU within 30 days of COVID-19 diagnosis. | 2021-01-07 |
| 33408209 | Testing used in screening, diagnosis and follow-up of COVID-19 has been a subject of debate. […] An important number of recommendations focused on the diagnosis of suspected cases (48%) and deisolation measures (11%). | 2021-01-07 |
| 33408218 | The RT-PCR data will be analysed to assess the diagnostic performance of individual biomarkers in predicting COVID-19-related outcomes, such as viral pneumonia, acute respiratory distress syndrome or bacterial pneumonia. | 2021-01-07 |
| 33408671 | Parents residing in Spain observed less play time in the high ability sample, and more time spent on homework, whether or not they have a diagnosis of high ability. | 2021-01-07 |
| 33408775 | The development of the experimental vaccines requires a plethora of molecular techniques as well as strict compliance with safety procedures. | 2021-01-07 |
| 33409021 | As a result, the virus may cause symptoms of an acute neurological event and should be taken into diagnostic consideration. | 2021-01-07 |
| 33409173 | Different diagnostic tools to detect SARS-CoV-2 are being used around the globe, but the identification of asymptomatic carriers of the disease is a serious challenge in countering the COVID-19 pandemic. | 2021-01-07 |
| 33409413 | As SARS-CoV-2 is pandemic and as its most severe consequences result from a dysregulated immunological response to infection, the ideal therapies should be inexpensive and should be able to be administered to non-hospitalized persons at the time of their initial diagnosis. | 2021-01-07 |
| 33409421 | However, due to the characteristics of this disease, delays in diagnosis and treatment in hospitalized patients may leave them with serious visual impairment. | 2021-01-07 |
| 33409588 | • Discharge diagnosis was significantly different as well, in particular a relative increase in the proportion of children presenting with traumatic injuries and a decrease of viral infections were observed. | 2021-01-07 |
| 33409832 | All hospitalized adult patients with a diagnosis of SARS-CoV-2 infection by rRT-PCR performed on a nasopharingeal sample from March 1 to March 18 in our institution were included. | 2021-01-07 |
| 33410130 | In this case, several detection methods have been established based on nucleic acid diagnostic techniques and immunoassays to achieve sensitive and specific detection of SARS-CoV-2. […] Nucleocapsid protein gene was tested as a model target, and the sensitivity for quantitative detection was as low as 10 copies/μl, which basically meet the needs of clinical diagnosis. […] In addition, with the advantages of lower material cost, shorter detection time, and no requirement for professional instrument in comparison with quantitative reverse transcription-polymerase chain reaction, this assay is expected to provide a powerful technical support for the early diagnosis and intervention during epidemic prevention and control. | 2021-01-07 |
| 33410174 | The Samples were subjected to RT - PCR or Rapid Antigen test for diagnosis of SARS CoV- 2. […] A cohort of 3745 patients with confirmed diagnosis of SARS CoV -2 infection in a tertiary care center in New Delhi, India were included in this study. | 2021-01-07 |
| 33410205 | The suspicion of a possible COVID-19-associated cutaneous manifestation prompted timely testing and diagnosis of SARS-CoV-2 infection. | 2021-01-07 |
| 33410259 | Myocardial infarction might be an important differential diagnosis to consider in deteriorating patients with COVID-19, especially if dyspnoea persists after acute infection. | 2021-01-07 |
| 33410394 | We suggest against using diagnostic imaging to improve triage of reverse transcriptase (RT)-PCR-confirmed COVID-19 patients, unless a patient has worsening respiratory status. […] We suggest the use of diagnostic imaging to improve sensitivity of appropriate triage in suspected COVID-19 patients who are RT-PCR negative but have moderate to severe symptoms and are suspected of a false-negative RT-PCR with high risk of disease progression. […] We suggest the use of diagnostic imaging to improve sensitivity of appropriate triage in suspected COVID-19 patients with moderate or severe clinical features who are without access to RT-PCR testing for SARS-CoV-2. | 2021-01-07 |
| 33410425 | The global research community faces urgent calls for the development of rapid diagnostic tools, effective treatment protocols, and most importantly, vaccines against the pathogen. | 2021-01-07 |
| 33410826 | Since then, several diagnostic approaches have been re-adapted, and also improved from the previous detections of SARS and MERS coronavirus. […] The best strategy to handle this situation seems to rely on a triad of detection methods: (i) highly sensitive and specific techniques as the gold standard method, (ii) easier and faster point of care tests accessible for large population screening, and (iii) serology assays to complement the direct detection and to use for surveillance. […] In this study, we assessed the techniques and tests described in the literature, their advantages and disadvantages, and the interpretation of the results. […] Other nucleic acid amplification methods have been shown to be adequate as point of care (POC) diagnostic tests with similar performance as RT-qPCR. | 2021-01-07 |
| 33410887 | However, olfaction has been evaluated solely on reported symptoms, after COVID-19 diagnosis, and in both mild and severe COVID-19 cases, but rarely has it been assessed in prospectively unselected populations. […] To evaluate the diagnostic value of a semiobjective olfactory test developed to assess patient-reported chemosensory dysfunction prior to testing for the presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients attending a COVID-19 screening facility. […] This prospective diagnostic study with participants and observers blinded to COVID-19 status was conducted in a COVID-19 screening center of a tertiary university hospital in France from March 23 to April 22, 2020. […] The COVID-19 status was assessed using reverse transcriptase-polymerase chain reaction to detect the presence of SARS-CoV-2 in samples collected via nasopharyngeal swab (reference standard) to calculate the diagnostic values of patient-reported chemosensory dysfunction and CODA. […] Olfactory dysfunction, either self-reported or clinically ascertained (CODA score ≤3), yielded similar sensitivity (0.31 [95% CI, 0.20-0.45] vs 0.34 [95% CI, 0.22-0.48]) and specificity (0.97 [95% CI, 0.96-0.98) vs 0.98 [95% CI, 0.96-0.99]) for COVID-19 diagnosis. […] In this prospective diagnostic study of outpatients with asymptomatic or mild to moderate COVID-19, systematically assessed anamnesis and clinical testing with the newly developed CODA were complementary and specific for chemosensory dysfunction. | 2021-01-07 |
| 33411127 | To examine their response to the pandemic, we analyzed their perspective, and association with psychiatric symptoms and stress among HCW with psychiatric diagnosis. […] Sixteen out of 129 HCWs reported a pre-existing psychiatric diagnosis (median age 32 years, 8 were females, 8 work in the emergency department). […] There is a growing importance to protect HCWs mental health, including those with pre-existing psychiatric diagnosis, and proactively counter psychosocial consequences of healthcare crises. | 2021-01-07 |
| 33411128 | The patients were divided in three groups depending on psychiatric diagnosis: delirium, severe mental illness (SMI) and non-severe mental illness (NSMI). | 2021-01-07 |
| 33411175 | The aim of this study is to evaluate the diagnostic performances of NS referred to NPA for SARS-CoV-2 in children. | 2021-01-07 |
| 33411332 | On admission, delirium was determined by the Diagnostic and Statistical Manual of Mental Disorders (5th edition) criteria, 4AT, m-Richmond Agitation Sedation Scale, or clinical impression depending on the site. | 2021-01-07 |
| 33411700 | To assess the effectiveness of this policy, VDH analyzed testing data for contacts of persons with a COVID-19 diagnosis. | 2021-01-07 |
| 33411707 | From 14 March to 16 May 2020, we enrolled all patients admitted to our ED that had a diagnosis of COVID-19 pneumonia. | 2021-01-07 |
| 33411737 | Here we present a straightforward and robust estimation of the diagnostic rate in each European country. […] The method to obtain the diagnostic rate is transparent and empirical. […] The estimation protocol is dynamic, and it has been yielding converging numbers for diagnostic rates in all European countries as from mid-April, 2020. […] Using this diagnostic rate, policy makers can obtain Effective Potential Growth updated every day, providing an unbiased assessment of the countries at greater risk of experiencing an uncontrolled situation. […] The method developed has been and will be used to track possible improvements in the diagnostic rate in European countries as the epidemic evolves. | 2021-01-07 |
| 33412174 | Sensitive and precise diagnostic tools are urgently needed. | 2021-01-07 |
| 33412272 | Upon diagnosis of secondary hemophagocytic lymphohistiocytosis, immunosuppression with anakinra and steroids was started, leading to a hepatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and viremia. […] In the differential diagnosis, an acute crisis of Wilson’s disease was raised by laboratory and genetic testing. | 2021-01-07 |
| 33412349 | The Diagnosis Manual of Mental Disorders fifth edition was used to identify the presence of major depressive symptoms. | 2021-01-07 |
| 33412544 | An observational study of 20 sequential bronchoscopic diagnostic sampling procedures was performed on mechanically ventilated patients with suspected ventilator-associated pneumonia. […] The Ambu Bronchosampler unit was a reliable, effective, and possibly safer technique for diagnostic sampling in ICU. | 2021-01-07 |
| 33412793 | The RDt index, on the other hand, is borrowed from the techniques of time series analysis for the trend of an event measurement that develops as a function of time. […] The RDt index does not take into account the time of infection, but the date of the diagnosis of positivity and for this reason it is defined as diagnostic replication index, as it aims to describe the intensity of the development of frequency for cases recognized as positive in the population.The comparison between different possible applications of the methods and the use of different types of monitoring data was limited to four areas for which complete individual data were available in March and April 2020. | 2021-01-08 |
| 33412796 | Through a web platform, it collects individual data of laboratory confirmed cases of SARS-CoV-2 infection and gathers information on their residence, laboratory diagnosis, hospitalisation, clinical status, risk factors, and outcome. | 2021-01-08 |
| 33412797 | Data relating to pregnant or post-partum women with a confirmed SARS-CoV-2 infection diagnosis addressing the maternities for outpatient visits or hospitalization were collected. | 2021-01-08 |
| 33412800 | to describe the organisation and the role of the Department of Prevention of the Local Health Unit (APSS) of Trento (Trentino-Alto Adige Region, Northern Italy) against the spread of COVID-19 in the population, in the management of possible cases (with only clinical criteria of influenza-like illness, ILI, without diagnostic swab) reported by General practitioners (GPs) and by Family paediatricians (FPs) during the initial phase of the pandemic COVID-19 in Trentino-Alto Adige Region. descriptive study. this study analysed the reports of patients with ILI sent to the Healthcare company from 17 March to 17 April 2020 by their GPs or FP and subsequently classified into: redundant reports (people already known to the healthcare company as confirmed or probable case COVID-19); reports inconsistent with ILI criteria (patients not known to APSS as probable/confirmed case; without ILI criteria); appropriate reports (patients not known to APSS as probable/confirmed case; with ILI criteria). proportion of GPs and FPs who participated to report system reporting at least one patient, out of the total number of GPs and FPs; frequency of patients reported as ILI; time (in days) to manage reported patients. | 2021-01-08 |
| 33412809 | In the case of serological tests, there are several aspects that have to be considered: why we perform the test, what population is tested, which are the parameters conditioning the results and their interpretation. to show how to quantify the uncertainty related to the validity of the serological test with respect to its predictive value and in particular the positive predictive value. the evaluation of a qualitative diagnostic test includes four distinct assessments: accuracy, empirical evidence, practical importance, and prevalence of the pathology. […] Accuracy is measured by the sensitivity and specificity of the test; empirical evidence is quantified by the likelihood ratio, respectively for a positive and negative test result; the practical importance of the result of a diagnostic test is assessed by the positive or negative predictive value. […] Prevalence of COVID-19 is substantial uncertainty and it is possible to estimate the apparent prevalence starting from the results obtained with a diagnostic test. at the moment, the knowledge about the accuracy of serological tests is limited and little attention is paid to confidence interval on point estimates. | 2021-01-08 |
| 33412813 | to explore clinical and epidemiological characteristics associated with an imaging feature of COVID-19 pneumonia at disease onset, in order to identify factors that may be evaluable by general practitioners at patient’s home, and which may lead to identify a more severe disease, needing hospitalization. this is a retrospective/prospective observational hospital cohort. the study population includes all patients consecutively admitted to the emergency department of Città della salute e della scienza University Hospital from 01.03 to 31.05.2020 with a confirmed diagnosis of SARS-CoV-2 infection. patients were classified in two groups according to the findings of X-ray imaging, lung ultrasound and chest computer tomography, as pneumonia or not pneumonia patients. in multivariable analysis, factors most strongly associated with emergency department admission with pneumonia were age, oxygen saturation <90% (adj OR 4.16 ;95%CI 1.44-12.07), respiratory rate >24 breaths/min (adj OR 6.50; 95%CI 2.36-17.87), fever ≥38° (adj OR 3.05; 95%CI 1.53-6.08) and the presence of gastroenteric symptoms (vomiting and diarrhea). | 2021-01-08 |
| 33412828 | to describe the course of Italian organized cancer screening programmes during the COVID-19 emergency; to provide estimates of the diagnosis of malignant or pre-malignant lesions that will face a diagnostic delay due to the slowing down of screening activities. quantitative survey of aggregated data for each Region and overall for Italy relating to screening tests carried out in the period January-May 2020 compared to those of the same period of 2019; estimate of diagnostic delays starting from the calculation of the average detection rate of the last 3 years available (specific by Region). | 2021-01-08 |
| 33412830 | A total of 3,129 women were included in the study. using multiple weighted logistic regression models, self-perceived knowledge level was analysed in relation with the following variables: age, education level, family size, cumulative incidence of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) cases until 7 April 2020 by province, presence of COVID-19-like symptoms, SARS-CoV-2 testing, and COVID-19 diagnosis. the prevalence of self-perceived poor/medium knowledge was 57%. […] In multivariable logistic regression analyses, the odds ratio (OR) of self-perceived poor/medium COVID-19 knowledge level was increased for low/medium compared with high education level (OR 1.57; 95%CI 1.34-1.84), and decreased for SARS-CoV-2 testing (OR 0.25; 95%CI 0.16-0.39) and COVID-19 diagnosis (OR 0.20; 95%CI 0.07-0.60). | 2021-01-08 |
| 33412833 | A total of 34 papers were analyzed, which document the profound clinical, organizational and procedural changes introduced in mental health services following this exceptional and largely unforeseen planetary event.Among the main innovations recorded everywhere, the strong push towards the use of telemedicine techniques should be mentioned: however, these require an adequate critical evaluation, which highlights their possibilities, limits, advantages and disadvantages instead of simple triumphalist judgments. | 2021-01-08 |
| 33412986 | This case report illustrates the successful use of telemedicine and remote patient data acquisition to make a life-saving diagnosis. | 2021-01-08 |
| 33413026 | The association between initial illness and abnormal chest x-ray, 6MWT distance and perception of maximal exertion was investigated. 487 patients were offered an outpatient appointment, of which 153 (31%) attended for assessment at a median of 75 days after diagnosis. 74 (48%) had required hospital admission during acute infection. | 2021-01-08 |
| 33413059 | As the virus is transmitted by inhaling infectious respiratory droplets that are produced by sneezing or coughing, so early and rapid diagnosis of the disease can prevent infection and transmission. […] In this context, the current review article highlights the Artificial Intelligence methods that are playing an effective role in rapid, accurate and early diagnosis of the disease via pattern recognition, machine learning, expert system and fuzzy logic by improving cognitive behavior and reducing human error. […] In addition, CT scan, X-ray, MRI, and RT-PCR are some of the techniques that are being employed in the identification of COVID-19. […] We hope using AI techniques, the world can emerge from COVID-19 pandemic while mitigating social and economic crisis. | 2021-01-08 |
| 33413480 | This study aimed to investigate the value of chest CT radiomics for diagnosing COVID-19 pneumonia compared with clinical model and COVID-19 reporting and data system (CO-RADS), and develop an open-source diagnostic tool with the constructed radiomics model. […] The diagnostic performance was assessed by receiver operating characteristics curve (ROC) analysis, calibration curve, and decision curve analysis (DCA). […] An easy-to-use open-source diagnostic tool was developed using the combined model. | 2021-01-08 |
| 33413610 | During COVID-19, diagnostic serological tools and vaccines have been developed. […] SARS-CoV-2 spike and nucleocapsid proteins are both vaccine and serological diagnostic targets. | 2021-01-08 |
| 33413717 | For example, robotics, artificial intelligence, and digital technology have been deployed in hospitals and public areas for maintaining social distancing, reducing person-to-person contact, enabling rapid diagnosis, tracking virus spread, and providing sanitation. | 2021-01-08 |
| 33414132 | Hence, the MRF Scientific Advisory Council and Breakthrough Consortium, a group that includes clinicians and scientists, reconvened to facilitate intensive discussions on thematic areas essential to melanoma researchers and patients alike - prevention, detection, diagnosis, metastatic dormancy and progression, response and resistance to targeted and immune-based therapy, and the clinical consequences of COVID-19 for melanoma patients and providers. | 2021-01-08 |
| 33414225 | Our results may suggest that in children, neurologic involvement in COVID-19 is rare, neuroimaging has a low yield in diagnosis, and acute neuroimaging should involve careful risk-benefit analysis. | 2021-01-08 |
| 33414483 | Univariate analysis, showed a significant relationship between death and age, male gender, decreased lymphocyte counts, need for respiratory support, comorbidities and diagnosis of MF, while no association with essential thrombocythemia (ET), polycythemia vera (PV), and prefibrotic-PMF (pre-PMF) was found. […] Regarding MPN-directed therapy ongoing at the time of COVID-19 diagnosis, Ruxolitinib (Ruxo) was significantly more frequent in patients who died in comparison with survivors (p = 0.006). […] In conclusion, we found a high risk of mortality during COVID-19 infection among MPN patients, especially in MF patients and/or discontinuing Ruxo at COVID-19 diagnosis. | 2021-01-08 |
| 33414763 | Anterior spinal artery occlusion and possibly transverse myelitis were considered as differential diagnosis of long segment myelopathy. | 2021-01-08 |
| 33415083 | SARS-CoV-2 nucleic acid testing (NAT) has been routinely used for COVID-19 diagnosis during this pandemic; however, there have been concerns about its high false negative rate. | 2021-01-08 |
| 33415577 | Just 21.4% of respondents reported no negative effects from the pandemic on diagnostic practice patterns, and just 19.1% reported no negative effect on patient follow-up practices. | 2021-01-08 |
| 33415590 | Optical coherence tomography (OCT) demonstrated hyper-reflectivity band, in the outer nuclear layer and outer plexiform layer, nasal to the fovea of the right eye, and hyperreflective patch in outer retina segmentation en-face OCT, suggestive of the diagnosis of AMN. […] Nine days after AMN diagnosis, dyspnea, malaise, and cough was initiated. | 2021-01-08 |
| 33415689 | Patients were grouped based on trauma aetiology and diagnosis. | 2021-01-08 |
| 33416425 | Seven themes were identified as barriers to symptom reporting or accessing healthcare: lack of knowledge of the disease and its treatment, fear of the disease and fear of subsequent treatments or requirements, stigmatization attached to having a disease, invasion of privacy, low concern about symptoms, economic consequences of disease diagnosis, and challenges related to attending a healthcare facility. | 2021-01-08 |
| 33416429 | Our results indicate important sex-dependent differences in the diagnosis, clinical manifestation, and treatment of patients with COVID-19. | 2021-01-08 |
| 33416804 | We align this commentary with the tenets of the sociology of diagnosis, which argue that even though there are material realities of disease, their social form and consequence cannot be separated from the tangible nature of illness and its management. | 2021-01-08 |
| 33416859 | The analysis was adjusted for differences in demographic characteristics, pre-existing comorbidities, and period of diagnosis. […] A delayed diagnosis in non-Italian cases could explain their worse outcomes compared to Italian cases. […] Ensuring early access to diagnosis and treatment to non-Italians could facilitate the control of SARS-CoV-2 transmission and improve health outcomes in all people living in Italy, regardless of nationality. | 2021-01-08 |
| 33417084 | As misinformation thrives in crisis periods, well-designed studies are needed to flatten the infodemic curve regarding prevention, diagnosis, and long-term complications of COVID-19. | 2021-01-08 |
| 33417113 | So, the goal of the present study is to learn from the pathophysiology of COVID-19 clinical features, laboratory results, and high-resolution CT manifestations in different stages of disease severity to provide significant reference values for diagnosis, prevention, and treatment. […] Correlating them can make it possible for physicians and radiologists to quickly obtain the final diagnosis and staging of the COVID-19 pneumonia. | 2021-01-08 |
| 33417193 | This observational study was conducted on the patients of Imam Hossein Hospital, and 361 adult patients (214 males) with confirmed diagnosis of COVID-19 from March 5, 2020 to April 3, 2020, were enrolled. | 2021-01-08 |
| 33417230 | PVS was defined as the duration of shedding of at least 21 days after diagnosis. […] According to univariate analysis, factors associated with PVS were immunosuppression (6.7% vs 21.7%, p = 0.02), increased interleukin-6 (IL-6) levels (≥ 35 ng/ml) at the time of diagnosis (43.4% vs 67.3%, p = 0.02), time from onset of symptoms to diagnosis (median days 7.0 vs 3.5, p = 0.001), intensive care unit admission (22.7% vs 43.5%, p = 0.02), and need for invasive mechanical ventilation (20.0% vs 41.3%, p = 0.01). […] The multivariate analysis indicated that immunosuppression, increased IL-6 levels at the time of diagnosis, time from onset of symptoms to diagnosis, and need for mechanical ventilation were independent factors associated with PVS. | 2021-01-08 |
| 33417610 | Therefore, researchers are trying to address various aspects that may help in diagnosis this pneumonia. | 2021-01-08 |
| 33417696 | A subset of 91 donations were evaluated by OVSARS2IgG and compared to PRNT titers for diagnostic accuracy. | 2021-01-08 |
| 33417840 | The diagnosis of COVID-19 was mainly made by clinical compatibility (N = 430). | 2021-01-08 |
| 33418105 | Considering the gravity of its impact there is an immediate need to develop a detection technique that is sensitive, specific, fast, and affordable for the clinical diagnosis of the disease. […] Several modern techniques exhibiting assured results with enhanced sensitivity and specificity against the SARS-CoV-2 associated viral components or immune response against it have been developed and may be implemented. […] The review deals with the conventional RT-PCR detection techniques and compares them to other detection platforms viz., biosensor based detection of antigens, fluorescent or colorimetric detection systems including CRISPR-Cas 13 based SHERLOCK kit, CRISPR Cas-9 based FELUDA test kit, CRISPR DETECTR kit, Next Generation Sequencing or microarray-based kits. […] These modern techniques are great as a point of care detection methods but should be followed by RT PCR based detection for the confirmation of COVID-19 status. | 2021-01-08 |
| 33418142 | Apart from major health concerns associated to the SARS-coronavirus-2 (SARS-CoV-2) pandemic, also the diagnostic workflow encountered serious problems. […] Selected samples of the routine diagnostic workflow at Clinical Microbiology Laboratories of four Dutch hospitals have been subjected to the rapid QIA P&A protocol and the results have been compared to routine diagnostic data. | 2021-01-08 |
| 33418182 | The rapid identification of pathogenic microorganisms plays a crucial role in the timely diagnosis and treatment strategies during a global pandemic, especially in resource-limited area. | 2021-01-08 |
| 33418230 | We used the i2b2 patient’s registry platform at the University of Florida Health Center to generate a count of patients using the international classification of diseases (ICD)-10 diagnosis codes for the period of October 1, 2015, through June 30, 2020. […] Patients with vitamin D deficiency were 4.6 times more likely to be positive for COVID-19 (indicated by the ICD-10 diagnostic code COVID19) than patients with no deficiency (P < 0.001). | 2021-01-08 |
| 33418595 | The most common diagnosis was pneumonia, observed in 123 patients (63 %). | 2021-01-08 |
| 33418886 | In this study, we compared five commercially available diagnostic assays for the diagnostic identification of SARS-CoV-2-specific antibodies. | 2021-01-09 |
| 33419177 | Lung ultrasound (LU) is becoming an increasingly important diagnostic tool in detecting lung involvement in Corona Virus Disease 2019 (COVID-19). | 2021-01-09 |
| 33419393 | Kidney biopsy may therefore have significant value in pulling together a clinical diagnosis, and may impact outcome if a treatable cause is identified. | 2021-01-09 |
| 33419456 | This review summarizes available evidence and provides a clinical decision algorithm with risk mitigation techniques to guide clinicians in care of the hypoxemic, non-intubated, patient during the COVID-19 pandemic. […] These techniques may improve oxygenation sufficiently to allow some patients to avoid intubation; however, patients must be carefully monitored for signs of increased work of breathing. | 2021-01-09 |
| 33419461 | Up to 25 asymptomatic SARS-CoV-2 positive study participants will be purposefully selected to explore the way in which asymptomatic men and women diagnosed with SARS-CoV-2 give meaning to their diagnosis and to the dialectic between feeling concurrently healthy and yet also being at risk for transmitting COVID-19. | 2021-01-09 |
| 33419483 | Exclusion criteria including those who had no definite history of head injury or the diagnosis of cSDH were made from a scheduled follow-up scan. […] The primary outcome was the interval between the initial head injury and the final radiological diagnosis of cSDH. […] For the primary outcome, the average interval between head injury and the diagnosis of cSDH was significantly longer at 56.6 days (49 to 74 days, SD 9.83 days) during the period from March to April 2020, versus 29.4 days (17 to 42 days, SD 8.59 days) in 2019 for the corresponding period (p = 0.00703). | 2021-01-09 |
| 33419752 | Delayed diagnosis can result in fatal embolic and haemorrhagic complications. | 2021-01-09 |
| 33420343 | Questions assessed patient characteristics and impacts of the pandemic on RUD diagnosis and management. | 2021-01-09 |
| 33420528 | The success of our online rotation highlights the merits of self-directed learning and flipped-classroom techniques. | 2021-01-09 |
| 33420641 | In fighting against COVID-19, effective diagnosis of infected patient is critical for preventing the spread of diseases. […] Due to limited availability of test kits, the need for auxiliary diagnostic approach has increased. […] Recent research has shown radiography of COVID-19 patient, such as CT and X-ray, contains salient information about the COVID-19 virus and could be used as an alternative diagnosis method. […] In order to reduce intra- and inter-observer variability, during radiological assessment, computer-aided diagnostic tools have been used in order to supplement medical decision making and subsequent management. […] Using ablation studies, we show the effectiveness of the enhanced images in improving the diagnostic accuracy. | 2021-01-09 |
| 33420842 | Tracheostomy formation facilitates liberation from mechanical ventilation with advantages for both the patient and wider critical care resource, and can be performed using both percutaneous dilatational and surgical techniques. | 2021-01-09 |
| 33420872 | Using UK Biobank resource, we investigated the association between circulating IGF-1 concentrations and mortality risk (available death data updated on 07 Sep 2020) among COVID-19 patients who had pre-diagnostic serum IGF-1 measurements at baseline (2006-2010). | 2021-01-09 |
| 33421032 | Typical and atypical neuroimaging features have been observed in some disease entities, so that familiarity with these imaging patterns appears reasonable and may assist clinicians in the differential diagnosis of COVID-19 CNS manifestations. | 2021-01-09 |
| 33421213 | Conversely, immunosuppression intensity and degree of reduction following COVID-19 diagnosis were not associated with either survival or acute allograft rejection. | 2021-01-09 |
| 33421278 | We confirm the importance of CBA in the serological diagnosis of RIA-negative MG. | 2021-01-09 |
| 33421281 | However, only 47 fulfilled the clinical criteria for the diagnosis of HF. | 2021-01-09 |
| 33421351 | Hence, understanding the CNS characteristics of COVID-19 can help us for better diagnosis and ultimately prevention of worse outcomes. | 2021-01-09 |
| 33421417 | The primary outcome variables were the facial fracture diagnosis, the abbreviated injury scale (AIS), injury severity score (ISS), and the mechanism of injury. | 2021-01-09 |
| 33421573 | Household contacts were tested at a median of 2 days (range, 1-7) after diagnosis of the index case, whereas non-household contacts (n = 296) were tested at a median of 6 days (range, 1-7) after exposure. | 2021-01-09 |
| 33421989 | National health registries were used to identify all hospitalized patients with a COVID-19 diagnosis. | 2021-01-10 |
| 33422034 | Mobile phones were used for surveillance, prevention, diagnosis, and communication demonstrating good performance, acceptance and usability by users, as well as feasibility of mobile phone under real life conditions and effectiveness in terms of contributing to a reduction of vectors/ disease and improving users-oriented behaviour changes. | 2021-01-10 |
| 33422083 | Assuming 100% specificity of the diagnostic assay, the FNR and sensitivity in this group of patients with discordant testing was 9.3% (95% CI 1.5-17.0%) and 90.7% (95% CI 82.6-98.9%) respectively. | 2021-01-10 |
| 33422421 | Establishing a standard of care in ophthalmic practice by modifying the conventional examination techniques and adopting tele-ophthalmology model to triage the patients can control the community spread of the disease. | 2021-01-10 |
| 33422820 | The sample comprised 43 individuals with a verified diagnosis of BD and 24 healthy controls. | 2021-01-10 |
| 33423106 | Non-hospitalized patients with a sudden loss of smell and a confirmed COVID-19 diagnosis were recruited by hospital call from February to April 2020. | 2021-01-10 |
| 33423180 | Rapid diagnostic testing for COVID-19 is key to guiding social distancing orders and containing emerging disease clusters by contact tracing and isolation. | 2021-01-10 |
| 33423415 | Within US telehealth, skin conditions have become the fifth most common diagnosis. | 2021-01-11 |
| 33423567 | Prompt diagnosis is the key to mitigate this situation. […] As several diagnostic tools for COVID-19 are already available and still others are under development, mandating a comprehensive review of the efficacy of existing tools and evaluate the potential of others. […] An ideal detection method should be sensitive, specific, rapid, cost-effective, and should allow early diagnosis of the infection as near as possible to the point of care that could alter the current situation for the better. […] Medical diagnostics is a highly dynamic field as no diagnostic method available for SARS-CoV-2 detection offers a perfect solution and requires more attention and continuous R&D to challenge the present-day pandemic situation. | 2021-01-11 |
| 33423804 | A high level of clinical suspicion, lower threshold for diagnostic imaging and aggressive early and extended thromboprophylaxis is indicated. | 2021-01-11 |
| 33423880 | Twomedical practices of an urban health center in Salamanca (Spain). ≥18 years diagnosed with SAR-CoV-2 between March 11th and April 20th. clinical-epidemiological chatacteristics, diagnosis, treatment and outcome at the end of study RESULTS: 122 patients (63.9% female), 19.7% social and health care workers y 4.9% from nursing homes. | 2021-01-11 |
| 33423918 | Presented results indicate that SQT is highly concordant with RT-PCR and should be useful for the diagnosis of COVID-19 in any clinical setting. | 2021-01-11 |
| 33424051 | We applied the statistical techniques cosine similarity and agglomerative hierarchical clustering analysis to examine and compare affinities in research preferences among them. | 2021-01-11 |
| 33424118 | The algorithm of the ensemble ML classifier has performed feature extraction using the advanced techniques of term frequency-inverse document frequency (TF/IDF) which is an effective information retrieval technique from the corona dataset. […] By using the machine learning techniques, the three-way COVID-19 stages are classified by the extraction of the feature using the data retrieval process. […] This study established the feasibility of techniques to analyze blood tests and machine learning as an alternative to rRT-PCR for detecting the category of COVID-19-positive patients. | 2021-01-11 |
| 33424133 | The diagnostic accuracies of GBDT, LR, and LR-5 were 0.889, 0.868, and 0.887, respectively. | 2021-01-11 |
| 33424144 | International Guidelines have voted for PCR as the Gold Standard in COVID diagnosis. […] But the diagnostic sensitivity of nasopharyngeal PCR decreases with increase in lapse between the infection and presentation to hospital. […] The aim of the study was to see if COVID antibody testing be coupled with PCR for diagnosis especially in patients presenting late (more than 14 days) of onset of infection? | 2021-01-11 |
| 33424145 | Real time PCR is still considered as standard method of diagnosis along with other serology, radiological and biochemical investigations. […] Thus, this review provides detailed knowledge about the different landscapes of disease incidence, etiopathogenesis, involvement of various organs, diagnostic criteria’s and treatment guidelines followed for management of COVID-19 infection since its inception. | 2021-01-11 |
| 33424386 | At present, quantitative real-time PCR (qRT-PCR) is a widely used diagnostic method. […] These constraints reflect the significant need for the development of alternative diagnostic options. | 2021-01-11 |
| 33424424 | The diagnostic ratio analyses of BC shows that wood burning contribution was too high during the lockdown situations. | 2021-01-11 |
| 33424426 | This research study should be helpful for further management and spatial diagnosis of water resource of river Damodar. | 2021-01-11 |
| 33424428 | Our point-of-care diagnostic system can be installed at a fixed place (stationary), and it can also be transported to various strategic places (itinerant). […] This research determines that the proposed point-of-care diagnostic system meets all requirements to set and operate molecular techniques to diagnose infectious diseases, such as COVID-19, with good laboratory conditions, secure and eco-efficient energy, supporting the health scheme to prevent and control the spread of the virus. | 2021-01-11 |
| 33424433 | It is observed that proposed method outperforms existing nonlinear dimensionality reduction techniques in low-dimensional representation for synthetic datasets. | 2021-01-11 |
| 33424652 | Since 2016, the project “Early Bird Diagnostic Protocol for Autism Spectrum Disorders (ASD)” funded by the Italian Ministry of Health has been operative at IRCCS Fondazione Stella Maris (FSM), Pisa (IT), with the main aim of developing early age-specific diagnostic protocols by longitudinally enrolling two different populations at risk for ASD: (i) toddlers with older siblings with ASD (FR) and (ii) toddlers referred by a child psychiatrist or pediatrician for suspected ASD (CR). | 2021-01-11 |
| 33424666 | The observed changes in mental health and the identified potential risk factors underlying these changes provide critical data justifying timely and public emergency-tailored preventive, diagnostic, and therapeutic mental health interventions, which should be integrated into future public health policies globally. | 2021-01-11 |
| 33424692 | There is a lack of control in disease early diagnosis and rapid evolution, which impacts both the medical and the economic system. | 2021-01-11 |
| 33424908 | Similar procedures could be easily deployed to produce diagnostic reagents and, eventually, could be adapted for rapid therapeutic responses. | 2021-01-11 |
| 33424917 | The numerous technological breakthroughs in this field have acknowledged personalized medicine as the next generation of diagnosis and treatment. […] Starting from the treatment of malaria, as a first more personalized therapeutic approach, it highlights the need of new diagnostic tools and therapeutic regimens based on individuals’ genetic background. | 2021-01-11 |
| 33424976 | This was an unlikely diagnosis in a patient with no known underlying lung condition and no other precipitating factors such as barotrauma. | 2021-01-11 |
| 33425046 | Chest CT is used in the COVID-19 diagnosis process as a significant complement to the reverse transcription polymerase chain reaction (RT-PCR) technique. […] We have developed inference engines that will turn X-ray machines into powerful diagnostic tools by using deep learning technology to detect COVID-19. […] This study was focused on the problem of multi-class classification (COVID-19, viral pneumonia, and normal), which is a rather difficult task for the diagnosis of COVID-19. […] These powerful diagnostic engines allow for the early detection of COVID-19 as well as distinguish it from viral pneumonia with similar radiological appearances. | 2021-01-11 |
| 33425051 | The preliminary diagnosis of COVID-19 empowers health experts and government professionals to break the chain of change and level the epidemic curve. […] Chest X-ray images to be used to diagnosis the COVID-19. […] In particular, the modified pre-trained CNN-ResNet50 based Extreme Learning Machine classifier (ELM) has proposed for different diagnosis abnormalities such as COVID-19, Pneumonia, and normal. […] This CNN model can help in the automatic diagnosis of COVID-19 cases and help decrease the burden on medicinal services frameworks. | 2021-01-11 |
| 33425089 | Because of these unique characteristics, carbon nanomaterials are explored in a wide range of fields, including the diagnosis and treatment of viruses. | 2021-01-11 |
| 33425132 | Real-time reverse transcriptase polymerase chain reaction (RT-PCR) tests for SARS-CoV-2 nucleic acid were performed using nasopharyngeal swabs (Novel Coronavirus PCR Fluorescence Diagnostic Kit, BioGerm Medical Biotechnology at the Nigeria Centre for Disease Control (NCDC) in Abuja. | 2021-01-11 |
| 33425263 | This study aimed to propose a dietary protocol for hospitalized patients with the diagnosis of acute respiratory infectious disease caused by COVID-19 based on Persian Medicine. | 2021-01-11 |
| 33425270 | In the current COVID-19 pandemic, there is a rising need for a rapid and reliable diagnostic tool. […] The aim of this study was to compare the diagnostic value of chest CT and RT-PCR in Iranian patients with suspected COVID-19. […] Chest CT had higher specificity in the diagnosis of COVID-19 than that of the previous studies. […] Therefore, it can play a crucial role in the early diagnosis. | 2021-01-11 |
| 33425271 | ROC curve analysis for diagnostic values of NLR and PLR showed that the areas under the ROC curves for NLR and PLR were 0.703 (95% CI: 0.64-0.76) and 0.535 (95% CI: 0.46-06), respectively. | 2021-01-11 |
| 33425272 | In this diagnostic accuracy study, all probable COVID-19 patients older than 16-year-old who were transferred to the hospital by the Tehran Emergency Medical Services (EMS) during the first month of the pandemic, entered to the study. | 2021-01-11 |
| 33425277 | Based on these results, the diagnosis of SARS-CoV-2 infection was retained. | 2021-01-11 |
| 33425279 | Following ICU administration and confirmed diagnosis of COVID-19, considering critical condition of the young patient, plasmapheresis was performed once on a daily basis, three doses of interferon beta(IFN-β-1b) was injected subcutaneously every other day and dexamethasone was given at a dose of 4 mg every 8 hours along with common antiviral regimen. | 2021-01-11 |
| 33425411 | COVID-19, as a global concern and pivotal issue in the healthcare system, could have various presentations, leading to difficulty in diagnosis and management. […] This report highlights the representation of MS in a young woman, which resulted in a COVID-19 diagnosis. | 2021-01-11 |
| 33425516 | The limited clinical diagnostic capacity emphasizes the need for a reliable diagnostic test. | 2021-01-11 |
| 33425644 | The results are compared with existing benchmark techniques. | 2021-01-11 |
| 33425645 | Secured medical image transmission requires adequate techniques for protecting patient privacy. | 2021-01-11 |
| 33425664 | Many face detection models have been created using several algorithms and techniques. | 2021-01-11 |
| 33425670 | The diagnosis of these poisonings is challenging as direct assays are not available in our setting. […] Indirect markers such as clinical features and laboratory results can lead to the diagnosis when direct assays are unavailable. | 2021-01-11 |
| 33425682 | There is a rapid accumulation of data on its epidemiology, clinical course, diagnosis, management, and complications. | 2021-01-11 |
| 33425696 | Comprehensively we recommend intervention only in emergency procedures during pandemic, use of personal protective equipment during all procedures, preoperative investigations for diagnosis and modifications in operation theatre, anesthesia and surgical techniques to reduce aerosols generation will minimize risk of infection transmission to health care workers. | 2021-01-11 |
| 33425823 | This review summarizes the literature on diagnosis, parameters of disease severity, and current treatment regimens. | 2021-01-11 |
| 33425958 | Controlled clinical research on famotidine for COVID-19 should follow, as well as the development of valid and reliable research diagnostic criteria to define and operationalize the features of a putative COVID-19 neuropsychiatric residual. | 2021-01-11 |
| 33425987 | Therefore, advances in the field of virus diagnosis and the development of new point-of-care testing kits become necessary globally. […] Several rapid nucleic acid diagnostic kits have been developed and validated using Cas9, Cas12, and Cas13 proteins. […] This review summarizes the CRISPR/Cas-based next-generation molecular diagnostic techniques and portability of devices for field-based utilization. | 2021-01-11 |
| 33425988 | These findings clearly indicate the potential of this inexpensive, sensitive, and specific molecular diagnostic test to extend our testing capabilities for the detection of SARS-CoV-2 to curtail COVID-19 transmission. | 2021-01-11 |
| 33426424 | Encrypted transmission is required to the Dentist for early diagnosis and treatment in Teledental system in this pandemic context. | 2021-01-11 |
| 33426426 | In doing so, the side effect profile must be taken into account, including hypersensitivity reactions, whose diagnostic and logistical management must aim at a safe and efficient therapy of the underlying disease. […] Therefore, research and development of suitable diagnostic methods for detection of immunologically caused side effects as well as detection of potential therapy responders and non-responders is of great importance. | 2021-01-11 |
| 33426467 | Reviewing published research highlights the pivotal roles of nanotechnology and biomaterials in the development and efficiency of detection techniques, e.g., by applying nanotechnology and nanomedicine as part of the road map in the treatment of coronavirus disease 2019 (COVID-19) patients. | 2021-01-11 |
| 33426483 | Our study reveals that a family medicine clerkship can be successfully delivered using telemedicine and remote learning techniques. | 2021-01-11 |
| 33426534 | We must develop strategies and techniques to study the impact of AI-based technologies on patient care outcomes and the clinical workflow. | 2021-01-11 |
| 33426630 | Three-hundred and twelve people with a clinically defined diagnosis of an ED and undergoing a specialist ED treatment in different Italian ED services before the spreading of COVID-19 pandemic filled in an online survey. | 2021-01-11 |
| 33426645 | Performing lung ultrasound during the clinical assessment of patients with suspicion of noncritical COVID-19 may increase the diagnostic rate of pulmonary involvement over other diagnostic techniques used in routine clinical practice. […] We compared 2 cohorts, differentiated by the use of lung ultrasound as a diagnostic tool. | 2021-01-11 |
| 33426733 | High suspicion is necessary, because the diagnosis of this potentially life-threatening condition in COVID-19 patients can be challenging. | 2021-01-11 |
| 33426894 | diagnostic research (IVDr) information on quantitative lipoprotein profiles (112 parameters) extracted from the raw 1D NMR data. […] All NMR methods gave highly significant discrimination of SARS-CoV-2 positive patients from controls and SARS-CoV-2 negative patients with individual NMR methods, giving different diagnostic information windows on disease-induced phenoconversion. | 2021-01-11 |
| 33427042 | Our report demonstrates that timely recognition of clinical signs and symptoms led to the appropriate diagnosis of an uncommon ECMO complication. | 2021-01-11 |
| 33427079 | We use standard regression techniques, including instrumental variables analysis addressing endogeneity on COVID-19 testing and deaths data as of the end of May and beginning of September. | 2021-01-11 |
| 33427241 | Owing to sensitive and specific HCR technology, this protocol can also be used as a diagnostic tool. | 2021-01-11 |
| 33427417 | The national lockdown imposed in Italy in March-May 2020 and the consequent assisted reproductive techniques (ART) activity blockage allowed to evaluate the conception ability of couples who suffered the postponement of ART cycles. | 2021-01-11 |
| 33427452 | Fast screening and diagnosis are thus crucial for quick isolation and clinical intervention. […] In this work, we showed that attenuated total reflection-Fourier transform infrared spectroscopy (ATR-FT-IR) can be a primary diagnostic tool for COVID-19 as a supplement to in-use techniques. | 2021-01-11 |
| 33427749 | T cells were evaluated using a 28-marker phenotypic panel, and findings were modelled against time from diagnosis, humoral and inflammatory responses. | 2021-01-11 |
| 33427998 | Lung ultrasound has a high accuracy for the diagnosis of pulmonary diseases; however, there are few prospective studies demonstrating that lung ultrasound can predict outcomes in COVID-19 patients. | 2021-01-11 |
| 33428057 | All patients discharged from Akershus University Hospital with a diagnosis of transient ischemic attack (TIA) or acute stroke from January to September 2020 were identified by hospital chart review. | 2021-01-11 |
| 33428110 | Several lung ultrasound (US) protocols for pneumonia diagnosis are used in clinical practice, but none has been proposed for COVID-19 patients’ screening in the emergency department. […] We adopted a simplified 6-scan lung US protocol for COVID-19 pneumonia diagnosis (LUSCOP) and compared its sensitivity with high resolution computed tomography (HRCT) in patients suspected for COVID-19, presenting to one Emergency Department from February 21st to March 15th, 2020, during the outbreak burst in northern Italy. […] COVID-19 pneumonia’s final diagnosis was based on real-time reverse-transcription polymerase chain reaction from nasal-pharyngeal swab and on clinical data. […] Out of 150 suspected COVID-19 patients, 131 were included in the study, and 130 had a final diagnosis of COVID-19 pneumonia. […] LUSCOP protocol showed optimal sensitivity and can be proposed as a simple screening tool for COVID-19 pneumonia diagnosis in the context of outbreak burst areas where prompt isolation of suspected patients is crucial for patients’ and operators’ safety. | 2021-01-11 |
| 33428446 | Studies including at least 5 paired nasopharyngeal swab and saliva samples and reporting diagnostic accuracy for SARS-CoV-2 detection. […] Data were independently extracted using standardized forms, and study quality was assessed using QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2). […] Among persons without a previous SARS-CoV-2 diagnosis, saliva was 7.9 percentage points less (CI, 14.7 percentage points less to 0.8 percentage point more) sensitive. | 2021-01-11 |
| 33428630 | The COVID-19 pandemic does not fit into prevailing Post-traumatic Stress Disorder (PTSD) models, or diagnostic criteria, yet emerging research shows traumatic stress symptoms as a result of this ongoing global stressor. | 2021-01-11 |
| 33428634 | In an outbreak, effective detection of the aetiological agent(s) involved using molecular techniques is key to efficient diagnosis, early prevention and management of the spread. | 2021-01-11 |
| 33428900 | Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is the gold standard method for the diagnosis of coronavirus disease (COVID-19) worldwide. […] Recently, new methods have been developed for nucleic acid detection and pathogen diagnosis using CRISPR-Cas systems. […] These methods present rapid and cost-effective diagnostic platforms that provide high sensitivity and specificity without the need for complex instrumentation. […] Here, we briefly describe the RT-qPCR method, and discuss its limitations in meeting the current diagnostic needs. […] We explain how the unique properties of various CRISPR-associated enzymes are utilized for nucleic acid detection and pathogen diagnosis. […] Then, we highlight the important features of CRISPR-based diagnostic methods developed for SARS-CoV-2 detection. | 2021-01-11 |
| 33428981 | Cas12 and Cas13 are CRISPR proteins that are efficient agents for diagnosis and combating single-stranded RNA (ssRNA) viruses. […] Thus, accurate and rapid diagnostic and therapeutic tools are essential for early detection and treatment of this widespread infectious disease. […] In this review, we talk about Cas12 and Cas13 CRISPR systems and their applications in diagnosis and treatment of RNA virus mediated diseases. […] Moreover, we highlight novel CRISPR based diagnostic platforms and therapies for COVID-19. […] We also discuss the challenges of diagnostic CRISPR based platforms as well as clarifying the proposed solution for high efficient selective in vivo delivery of CRISPR components into SARS-CoV-2-infected cells. | 2021-01-11 |
| 33428984 | Regression techniques were used to model changes in the number of confirmed cases and data was combined across states using meta analyses. | 2021-01-11 |
| 33428990 | Diagnostic real time reverse transcription PCR (rRT-PCR) is usually done using nucleic acid (NA) purified from the sample. | 2021-01-11 |
| 33429204 | In the present study, we upgraded Pyrococcus furiosus Argonaute (PfAgo) mediated nucleic acid detection method and established a highly sensitive and accurate molecular diagnosis platform for the large-scale screening of COVID-19 infection. […] The diagnostic results of clinic samples with SARS-CoV-2 PAND displayed 100% consistence with RT-qPCR test. | 2021-01-11 |
| 33429246 | The main end point was the deteriorated erectile function or ejaculatory control ability, defined by self-evaluation or by decreased International Index of Erectile Function-5 items (IIEF-5) scores or increased premature ejaculation diagnostic tool (PEDT) scores. | 2021-01-11 |
| 33429434 | Consequently, both econometric and spatial analysis techniques are recommended for tracking the spatiotemporal spread of this disease and for monitoring the effectiveness of policy measures across heterogeneous neighbourhoods. | 2021-01-11 |
| 33429476 | Herein, we describe the case of a 12-year-old boy who had a history of polymerase chain reaction-confirmed COVID-19 and developed MIS-C approximately three weeks after an initial diagnosis of COVID-19. | 2021-01-11 |
| 33429731 | The time from a positive diagnosis to a negative result of 2 consecutive nucleic acid tests (not on the same day), cure rate. | 2021-01-12 |
| 33429796 | The data was described and synthesized to summarize the diagnosis and management strategy of ACS, the preparation of catheter laboratory, and the protection of the medical staff in the context of COVID-19. […] Ethical approval is not required in this study, because it is a review with no recourse to patient identifiable information.Standardized diagnosis and treatment advice can help reduce the mortality of COVID-19 patients with ACS. | 2021-01-12 |
| 33429831 | Brochoalvelolar lavages (BALs) from patients suffering from hospitalized infections with SARS-CoV-2, other corona viruses (human coronavirus (HCoV)-229E, HCoV-OC43, HCoV-NL63, and HCoV-HKU1), Influenza virus type A and B, Haemophilus influenzae and Pneumocystis jirovecii were compared cytopathologically.The aim of the study was to evaluate if the cellular profile detectable in BAL may be specific for the respective pathogens and could lead to diagnosis of COVID-19 even in the absence of PCR results.Differential cytology and flow cytometry datasets of 62 patients were observed and compared.We observed a significant association between individual cell pattern changes and the causing pathogen, but no general cell distribution pattern.The cytology pattern of the BAL fluid in COVID-19 is not specific enough to use it as a sole diagnostic criterion, although it may support clinical decision making. | 2021-01-12 |
| 33429915 | The novel immunosensor has a significantly faster analysis time than the standard qPCR and is operated by a portable device which can enable on-site diagnosis of infection. | 2021-01-12 |
| 33430132 | American diagnostic criteria for PTSD have evolved across editions of the manual, and the current definition excludes naturally occurring medical illness (such as viral illness) as a qualifying trauma, ruling out this viral pandemic as the basis for a diagnosis of PTSD. […] This article provides an in-depth nosological consideration of the diagnosis of PTSD and critically examines three essential elements (trauma, exposure, and symptomatic response) of this diagnosis, specifically applying these concepts to the mental health outcomes of the COVID-19 pandemic. […] The current criteria for PTSD are unsatisfying for guiding the response to mental health consequences associated with this pandemic, and suggestions are made for addressing the conceptual diagnostic problems and designing research to resolve diagnostic uncertainties empirically. […] Options might be to revise the diagnostic criteria or consider categorization of COVID-19-related psychiatric syndromes as non-traumatic stressor-related syndromes or other psychiatric disorders. | 2021-01-12 |
| 33430260 | The aim of this study was to evaluate the diagnostic performance of circulating platelets (PLT)-derived extracellular vesicles (EVs) as biomarkers for Sars-Cov-2 infection, by setting a rapid and reliable test on unmanipulated blood samples. […] Diagnostic performance of PLT-EVs was evaluated by receiver operating characteristic (ROC) curve. | 2021-01-12 |
| 33430745 | The present review is based on the publicly available literature in order to explore the knowledge regarding epidemiology, virology, diagnosis, clinical features, pharmacological and therapeutic ways to treat the novel coronavirus. | 2021-01-12 |
| 33430850 | Advanced age, frailty, White-European ethnicity, a diagnosis of any co-morbidity and receipt of cardiovascular medications were associated with ceiling of care decisions. | 2021-01-12 |
| 33430924 | A confirmed diagnosis of COVID-19 infection, within the last 14 days, prior to randomization, as determined by PCR or other approved commercial or public health assay, in a specimen as specified by the test used. | 2021-01-12 |
| 33431331 | Retrospective unicenter observational cohort study that included patients under 14 years of age seen in the ED with a diagnosis of AA during the months of March to May 2019 (non-pandemic) and 2020 (pandemic). 90 patients were included (41 in non-pandemic and 49 in pandemic). […] No significant differences were observed in the rate of complicated AA in intraoperative diagnosis (35% vs 33%; p=0.870) or anatomopathology (35% vs 48%; p=0.222), nor in the number of postoperative complications, length of hospitalization and readmissions. […] An increase in the anatomopathological diagnosis of AA with periapendicitis was observed (47% vs 81%; p=0.001) CONCLUSION: During the pandemic, a delay from arrival at the ED until the surgery was observed in children diagnosed with AA. […] This delay resulted in an increase in the diagnosis of histologically evolved AA, but without an increase in the clinical complications of the disease. | 2021-01-12 |
| 33431356 | Universal screening for high-risk populations may facilitate earlier diagnosis of COVID-19 and implementation of control strategies. | 2021-01-12 |
| 33431524 | During a pandemic, it is easy to ‘think horses and not zebras’, and with a patient presenting with the classic coronavirus symptoms it would have been easy to jump to that as her diagnosis. […] After a careful history and examination, it became clear that there was another underlying diagnosis. | 2021-01-12 |
| 33432268 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus-specific reverse transcriptase-polymerase chain reaction (RT-PCR) represents the diagnostic gold standard. | 2021-01-12 |
| 33432278 | The focus was on clinical reasoning, counseling, and the following the Association of American Medical Colleges (AAMC) Core Entrustable Professional Activities (EPAs): 1 (history and physical exam), 2 (prioritize a differential diagnosis), 3 (recommend and interpret diagnostic tests), and 5 (document a clinical encounter). | 2021-01-12 |
| 33432282 | The assortment of reporting techniques alongside other issues, such as underreporting and budgetary constraints, makes predicting the spread and lethality of the virus a challenging task. | 2021-01-12 |
| 33432288 | Statistical analysis presented by the World Health Organization and other health organizations explicitly indicates that optimized support and care extended to infected persons is the key to therapy, and the clinical effectiveness of alternative techniques is still under study. | 2021-01-12 |
| 33432301 | Pulmonary involvement and PCR confirmed the diagnosis. | 2021-01-12 |
| 33432306 | We also discuss diagnosis, medical management, and surgical approach to an upper extremity arterial thromboembolism in a patient with coronavirus disease 2019, to highlight the challenges of hypercoagulability in such patients. | 2021-01-12 |
| 33432307 | The importance of this study is the efficacy of “symptoms only” approach at a screening clinic for coronavirus disease 2019 (COVID-19) diagnosis in low- and middle-income countries (LMIC) setting. […] Rapid triaging for confirmatory diagnosis of COVID-19 is feasible at screening clinic based on history taking alone by training of primary care physicians. | 2021-01-12 |
| 33432308 | The lack of effective methods of early diagnosis and accurate detection may result in severe infection as well as mortality. […] Therefore, it is urgently required that rapid, selective, and accurate techniques for detecting pathogenic viruses are developed. […] These representative studies demonstrate appealing performance as biosensors and hold great promise for clinical diagnosis. | 2021-01-12 |
| 33432534 | The gold standard for COVID-19 diagnosis is currently a real-time reverse transcriptase polymerase chain reaction (RT-PCR) to detect SARS-CoV-2. […] We performed a clinical diagnostic study comparing the IM2 swab to the Copan FLOQSwab. […] Forty patients with a known diagnosis of COVID-19 and 10 healthy controls were recruited. | 2021-01-12 |
| 33432912 | We report on a set of pragmatic recommendations for the prevention, diagnosis, and management of patients with COVID-19 and AKI in low- and middle-income countries (LMICs). […] For the diagnosis of AKI, we suggest that any patient with COVID-19 presenting with an elevated serum creatinine level without available historical values be considered as having AKI. | 2021-01-12 |
| 33433081 | The aim of this study was to use the 3D imaging software, ITK-SNAP as a platform to define a gold standard for anatomically accurate boundaries of the nasal airway in 3D CBCT and to create a more reliable and precise 3D CBCT segmentation of the nasal airway for assisting diagnosis, treatment, and monitoring of nasal airway obstruction and OSAS. […] This information can be useful in the diagnosis and treatment of airway compromised dental patients. | 2021-01-12 |
| 33433671 | To review the extracardiac radiologic findings of MIS-C in a group of children and young adults with a confirmed diagnosis of MIS-C. […] The diagnosis of MIS-C and its distinction from other pathologies should be primarily based on clinical presentation and laboratory evidence of inflammation because imaging findings are nonspecific. | 2021-01-12 |
| 33433784 | However, to predict protein interactions with artificial intelligence techniques, protein sequences need to be mapped. | 2021-01-12 |
| 33434269 | However, before antibody testing, 482 of them (67%) had no previous diagnosis of SARS-CoV-2-infection. | 2021-01-12 |
| 33434663 | This assay can be a useful tool for a proper patient management, because the level and duration of viral replication are important factors to assess the risk of transmission and to guide decisions regarding the isolation and release of patients; an accurate diagnosis is critical information, whereas the current COVID-19 pandemic represents the biggest current global health problem. | 2021-01-12 |
| 33434668 | The COVID-19 diagnosis is difficult and ambiguous due to nonspecific symptoms. […] Thus, this work aims to provide epidemiology information about the burden of COVID-19 in Mexican outpatients and to identify symptomatic COVID-19 profiles that could help in the early diagnosis of the disease. […] The incidence of SARS-CoV-2 was high among outpatients with a significant proportion of presymptomatic carriers, and thus it is necessary to increase testing and continue SARS-CoV-2 surveillance with a better description of signs and symptoms; in this regard, we identified three symptomatic profiles that could help in the diagnosis of COVID-19. | 2021-01-12 |
| 33434671 | Multiple molecular kits are available for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) worldwide, with many lacking proper clinical evaluation due to the emergency caused by the coronavirus disease 2019 (COVID-19) pandemic, particularly in developing countries. […] This study was conducted to evaluate the clinical performance of the Isopollo COVID-19 detection kit (M Monitor, South Korea) for reverse transcription loop-mediated isothermal amplification (RT-LAMP) SARS-CoV-2 diagnosis, using the SARS-CoV-2 reverse transcription polymerase chain reaction (RT-PCR) protocol as the gold standard. […] Proper clinical performance evaluation studies by regulatory agencies in developing countries such as Ecuador should be mandatory prior to clinical use authorization of SARS-CoV-2 diagnosis kits, particularly when those kits lack either US Food and Drug Administration or country of origin clinical use authorization. | 2021-01-12 |
| 33434780 | Different techniques, including genome sequencing, structural feature classification by electron microscopy, and chest imaging using computed tomography, are primarily used to diagnose and screen SARS-CoV-2 suspected individuals. […] Determination of the viral structure, surface proteins, and genome sequence has provided a design blueprint for the diagnostic investigations of novel SARS-CoV-2 virus and rapidly emerging diagnostic technologies, vaccine trials, and cell-entry-inhibiting drugs. […] This report also aims to review recently established diagnostic technologies and developments in surveillance measures for SARS-CoV-2 as well as the characteristics and performance of emerging techniques. […] We also describe promising point-of-care (POC) diagnostic technologies that are under consideration by researchers for advancement beyond the proof-of-concept stage. […] Developing novel diagnostic techniques needs to be facilitated to establish automatic systems, without any personal involvement or arrangement to curb an existing SARS-CoV-2 epidemic crisis, and could also be appropriate for avoiding the emergence of a future epidemic crisis. | 2021-01-12 |
| 33435711 | Our objective is to evaluate the diagnostic accuracy of a DL algorithm and the performance of portable handheld retinal cameras in the detection of DR in a large and heterogenous type 2 diabetes population in a real-world, high burden setting. […] The DL algorithm reached a good diagnostic accuracy for more than mild DR in a real-world, high burden setting. | 2021-01-13 |
| 33435943 | Furthermore, the integration of MRI techniques and cognitive assessment in combination with data on behavioral, biological and environmental variables will provide an opportunity to examine brain structure and cognitive function in relation to health behavior and air pollution, as well as other factors affecting resilience against and vulnerability to adverse changes in brain structure and cognitive aging. | 2021-01-13 |
| 33435973 | In this prospective, single centre, diagnostic accuracy cohort study, consecutive adults (≥ 18 years) presenting with symptoms consistent with COVID-19 or previous contact to infected individuals, admitted to the emergency department and supposed to be referred to general ward were included in March and April 2020. […] Of 165 participants (56.4% male, 71 ± 16 years) included in the study, the diagnosis of COVID-19 was confirmed with RT-PCR and AB tests in 13 participants (prevalence 7.9%). | 2021-01-13 |
| 33436122 | Self-collected swab techniques can overcome many of the disadvantages of a nasopharyngeal swab, but they require evaluation. […] Three self-collected non-nasopharyngeal swab techniques (saline gargle, oral swab and combined oral-anterior nasal swab) were compared to a nasopharyngeal swab for SARS-CoV-2 detection at multiple COVID-19 assessment centers in Toronto, Canada. […] These alternative collection techniques are cheap and can eliminate barriers to testing, particularly in underserved populations. | 2021-01-13 |
| 33436362 | Diagnosis was made based on positive transthoracic echocardiogram (TTE) findings and a raised troponin, not in the context of suspected acute coronary syndrome. | 2021-01-13 |
| 33436406 | OSA diagnosis and COVID-19 infection were extracted from the hospital discharge, causes of death and infectious diseases registries in individuals who participated in the FinnGen study (n=260 405). | 2021-01-13 |
| 33436416 | These themes highlight the unintended consequence on families, siblings, disease diagnosis, and hospital-based care provision. | 2021-01-13 |
| 33436435 | To foster collaborations between microbiologists and natural history collections, we provide recommendations for integrating vouchering techniques and archiving of microbiological samples into host-pathogen studies. | 2021-01-13 |
| 33436456 | Therefore, rapid diagnosis in conjunction with infection prevention measures is important to prevent transmission of the diseases. | 2021-01-13 |
| 33436471 | The most common symptoms of confirmed COVID-19 were cough, fatigue, myalgia and headache; whereas self-reported fever (OR 3.0, 95% CI 2.4 to 3.9), anosmia (OR 3.3, 95% CI 2.6 to 4.4) and ageusia (OR 2.9, 95% CI 2.3 to 3.8) were most strongly associated with a positive COVID-19 diagnosis by RT-PCR or serology. […] COVID-19 presents in a similar way to other mild community-acquired respiratory diseases, but the presence of fever, anosmia and ageusia can assist the specific diagnosis. | 2021-01-13 |
| 33436939 | The COVID-19 pandemic caused by the SARS-CoV-2 virus motivates diverse diagnostic approaches due to the novel causative pathogen, incompletely understood clinical sequelae, and limited availability of testing resources. […] Given the variability in viral load across and within patients, absolute viral load quantification directly from crude lysate is important for diagnosis and surveillance. […] More broadly, digital droplet assays provide a potential method for nucleic acid measurement and infectious disease diagnosis with limited sample processing, underscoring the utility of such techniques in laboratory medicine. | 2021-01-13 |
| 33437098 | Diabetic ketoacidosis (DKA) is a life-threatening emergency in children and adolescents with manifestation of type 1 diabetes mellitus (DM1) and often associated with delayed diagnosis or previous diagnostic errors. […] The centers also documented their assessment, if the presentation was delayed or the diagnosis was not made on the first medical consultation. […] Of the patients 31% had either a delayed presentation or a missed diagnosis. […] Age <6 years, migration background and delayed diagnosis were the main risk factors. | 2021-01-13 |
| 33437132 | Shortage of RT-PCR test kits and delays in obtaining test results calls for alternative methods of rapid and reliable diagnosis. | 2021-01-13 |
| 33437173 | Hence, there is a need for a less expensive and faster diagnostic model to identify the positive and negative cases of COVID-19. […] Therefore, this study develops six predictive models for COVID-19 diagnosis using six different classifiers (i.e., BayesNet, Logistic, IBk, CR, PART, and J48) based on 14 clinical features. […] The results could help in the early diagnosis of COVID-19, specifically when the RT-PCR kits are not sufficient for testing the infection and assist countries, specifically the developing ones that suffer from the shortage of RT-PCR tests and specialized laboratories. | 2021-01-13 |
| 33437283 | To evaluate the diagnostic value of the rtRT-PCR test and CT in patients presenting with typical clinical symptoms of COVID-19. […] It should be noted that a negative result in the rtRT-PCR test does not rule out the possibility of COVID-19 diagnosis in patients whose symptom duration is longer than five days, who are elderly with comorbidities and in particular who present with fever and shortness of breath. […] In these patients, typical CT findings are diagnostic for COVID-19. | 2021-01-13 |
| 33437347 | Since the widespread of acute respiratory syndrome infection caused by coronavirus-19, unenhanced computed tomography (CT) was considered a useful imaging tool commonly used in early diagnosis and monitoring of patients with complicated Covid-19 pneumonia. | 2021-01-13 |
| 33437464 | To compare different pooling methods in an attempt to improve the COVID-19 PCR diagnostic capacities. protocols in a simulation study, across variety of scenarios. ), which minimizes the number of terminal pools and manages to retain savings compared to other protocols, despite marginally longer processing times. | 2021-01-13 |
| 33437493 | Results will be stratified by the African geographic region, diagnostic methods and co-morbidity. […] COVID-19 distribution data will be shown by interest variables such as residence/geographic region, diagnostic methods, type of co-morbidity and outcomes of co-morbidity. | 2021-01-13 |
| 33437534 | State-of-the-art nanopore sequencing enables rapid and real-time identification of novel pathogens, which has wide application in various research areas and is an emerging diagnostic tool for infectious diseases including COVID-19. […] Here, we review recent progress and future development trends of 2D materials and their ångström- and nano-scale pore-based nucleic acid (NA) sequencing including fabrication techniques and current and emerging sequencing modalities. | 2021-01-13 |
| 33437562 | Reasons that hamper an earlier diagnosis of COVID-19 include the unspecific and mild symptoms during the first stage, the delay in the diagnosis and specific management caused by the requirement of a real-time reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2 for the diagnosis of COVID-19, and the insufficient sensitivity of the RT-PCR-SARS-CoV-2, converse to what is recommended for a screening test during an outbreak. […] More sensitive and earlier diagnostic tools for COVID-19 should be unraveled as a key strategy for a breakthrough change in the disease course and response to specific therapies, particularly those that target the blockage of viral shedding. […] We aimed to create an accurate, sensitive, easy-to-perform, and intuitive clinical scoring for the diagnosis of COVID-19 without the need for an RT-PCR-SARS-CoV-2 (termed The AndroCoV Clinical Scoring for COVID-19 Diagnosis), resulting from a 1,757 population cohort, to eventually encourage the management of patients with a high pre-clinical likelihood of presenting COVID-19, independent of an RT-PCR-SARS-COV-2 test, to avoid delays and loss of appropriate timing for potential therapies. […] Methods This is a post-hoc analysis of clinical data prospectively collected of the Pre-AndroCoV and AndroCov Trials, which resulted in scorings for the clinical diagnosis of COVID-19 based on the likelihood of presenting with actual COVID-19 according to the number of symptoms, presence of anosmia, and known positive household contact. […] Conclusion The AndroCoV clinical scoring for COVID-19 diagnosis was demonstrated to be a feasible, easy, costless, and sensitive diagnostic tool for the clinical diagnosis of COVID-19. […] Because the clinical diagnosis of COVID-19 avoids delays in specific treatments, particularly for high-risk populations, prevents false-negative diagnosis, and reduces diagnostic costs, this diagnostic tool should be considered as an option for COVID-19 diagnosis, at least while SARS-CoV-2 is the prevailing circulating virus and vaccination rate is below the required for herd immunity. | 2021-01-13 |
| 33437679 | Delayed TB diagnosis and treatment perpetuate the high burden of TB-related morbidity and mortality in resource-constrained settings. | 2021-01-13 |
| 33437684 | Age, gender, place of residence, clinical diagnosis and the operative procedure performed were included in the data profile for analysis. | 2021-01-13 |
| 33437915 | Given the high rates of thrombo-embolic events in COVID-19 patients, PE should be in the differential diagnosis of ST elevation, particularly in younger patients with few risk factors for coronary artery disease. | 2021-01-13 |
| 33437921 | On the other hand, transthoracic echocardiography (TTE) and TOE represent the first-line imaging exams for the diagnosis of infective endocarditis (IE). […] In COVID-19 patients, echocardiography remains the leading imaging exam for the diagnosis of IE. | 2021-01-13 |
| 33437922 | Echocardiography showed a poor left ventricular systolic function with apical ballooning consistent with the diagnosis Takotsubo cardiomyopathy. | 2021-01-13 |
| 33437952 | Comorbidity prevalences were calculated 1 and 5 years from cancer diagnosis. […] Haematological cancer survivors had large elevated risks persisting for >10 years (HR overall 15.17, 7.84-29.35; HR >10 years from cancer diagnosis 10.06, 2.47-40.93). […] Survivors of other cancers had evidence of raised risk up to 5 years from cancer diagnosis only (HR >5 years 2.22, 1.31-3.74). | 2021-01-13 |
| 33437971 | The objective of this systematic review and meta-analysis is to outline patient characteristics, challenges in diagnosis and treatment, and outcomes of patients with lung cancer with COVID-19. | 2021-01-13 |
| 33438132 | These results indicate that point-of-care LUS has the potential to be an initial imaging modality for the diagnosis of pneumonia. […] The LUS diagnosis of ventilator-associated pneumonia in intensive care units is more challenging in comparison with the diagnosis of community-acquired pneumonia in emergency departments due to the limited access to the mechanically ventilated patients and the high prevalence of atelectasis. […] However, several studies have demonstrated that the combination of LUS findings with other clinical markers improved the diagnostic accuracy. | 2021-01-13 |
| 33438491 | Telecardiology tools have improved bedside diagnosis when introduced as part of COVID-19 care by remote supervision and interpretation of POCUS and echocardiographic data. […] Evidenced based use of Tele-ICU can prevent delay in cardiac diagnosis, optimize safe use of expert resources and ensure timely care in the setting of critically ill cirrhosis, ACLF and liver transplantation in the COVID-19 era. | 2021-01-13 |
| 33438544 | For the diagnosis of the coronavirus disease, due to the growing number of cases, a limited number of test kits for COVID-19 are available in the hospitals. […] Hence, it is important to implement an automated system as an immediate alternative diagnostic option to pause the spread of COVID-19 in the population. | 2021-01-13 |
| 33438548 | To evaluate the diagnostic performance of texture analysis and machine learning models for the diagnosis of Covid-19 interstitial pneumonia in Chest X-ray images. | 2021-01-13 |
| 33439059 | Based on the type of diagnostic assay, the primary targets are viral genome (RNA) and encoded proteins. | 2021-01-13 |
| 33439160 | Here, we describe a polystyrene-toner (PS-T) centrifugal microfluidic device manually controlled by a fidget spinner for molecular diagnosis of COVID-19 by RT-LAMP, with integrated and automated colorimetric detection. | 2021-01-13 |
| 33439678 | Trainees suggested several modifications of teaching techniques to improve their participation and concentration in class. | 2021-01-13 |
| 33439938 | A descriptive analysis of the survey topics was performed: adherence to social restriction measures, diagnosis of the new coronavirus, work situation and income, difficulties in routine activities, presence of comorbidities, psychological issues, and access to health services. | 2021-01-13 |
| 33439993 | It adapts the Poisson pseudo-maximum-likelihood (PPML) and the quantile regression techniques to effectively exploit the non-linear estimates of the data in order to derive non-biased point estimates at each quantile and make interquantile comparisons. | 2021-01-13 |
| 33440111 | Myopericarditis should be included as a differential diagnosis for patients with suspected COVID-19. | 2021-01-13 |
| 33440114 | A multi-modal diagnostic and monitoring approach including both thromboelastometry and SCT such as plasma fibrinogen and D-dimer concentrations is recommended. | 2021-01-13 |
| 33440299 | The role of lung function testing is well defined for the diagnosis of various diseases and conditions. | 2021-01-13 |
| 33440622 | A summary study testing 50 serum samples highlighted an epitope of the N protein (region 155-71) providing good diagnostic performance in discriminating Covid-19 positive vs. healthy individuals. | 2021-01-14 |
| 33440649 | Biomarkers to reliably predict the patient’s clinical cause of the virus infection, ideally, to be applied in point of care testing or through routine diagnostic approaches, are highly needed. | 2021-01-14 |
| 33440674 | For better interpretability of the results, we applied visualization techniques to provide visual explanations for the models’ predictions. | 2021-01-14 |
| 33441063 | More is expected to come in the near future from using such advanced machine learning techniques in combating this pandemic. | 2021-01-14 |
| 33441073 | The extent of neurological involvement in SARS-CoV-2 infection warrants the necessity of further research to systematically classify neurological complications associated with SARS-CoV-2 infection, its diagnosis, and treatment. | 2021-01-14 |
| 33441188 | In additional analyses, the most frequent cardiovascular diagnosis was cardiomyopathy (34%), the most common cancer drug leading to referral was trastuzumab (29%), and the most prevalent cancer type was breast cancer (42%). | 2021-01-14 |
| 33441367 | To investigate this we will conduct a systematic review that will identify what messages and behaviour change techniques have the potential to optimise the effect on population behaviour in relation to reducing transmission of respiratory infections. | 2021-01-14 |
| 33441395 | These results clarify Ag concentration distributions in clinical samples, providing insight into the performance of Ag RDTs and offering a new approach to diagnosis of COVID-19. | 2021-01-14 |
| 33441822 | In this paper, deep learning is coupled with explainable artificial intelligence techniques for the discovery of representative genomic sequences in SARS-CoV-2. […] Finally, the primer is synthesized and tested on patient samples (n = 6 previously tested positive), delivering a sensitivity similar to routine diagnostic methods, and 100% specificity. | 2021-01-14 |
| 33442244 | An electronic literature search was done using PubMed to gather information on the pathogenesis, transmission of infection, clinical symptoms, diagnosis, and therapeutic options for COVID-19. […] Rapidly increasing amounts of information about the diagnosis and treatment of patients with SARS-CoV-2 allow a better understanding of the etiology and course of the infection. […] In the current epidemiological situation, readily accessible information helps minimize the time to acquire knowledge and focus on prevention methods, diagnostic and treatment options. | 2021-01-14 |
| 33442550 | We discuss the characteristics and differential diagnosis of acute kidney injury, as well as management of immunosuppression in connection with overall clinical status and evolution of kidney function. | 2021-01-14 |
| 33442553 | We therefore aimed to assess and compare the diagnostic accuracy of LUS and computed tomography (CT) in suspected COVID-19 patients. […] We calculated diagnostic accuracy measures for LUS and CT using both PCR and multidisciplinary team (MDT) diagnosis as reference. […] LUS specificity increased to 80% (95% CI 69.9-87.9) compared to MDT diagnosis, with an AUROC of 0.85 (95% CI 0.79-0.91). […] LUS and CT have comparable diagnostic accuracy for COVID-19 pneumonia. […] LUS can safely exclude clinically relevant COVID-19 pneumonia and may aid COVID-19 diagnosis in high prevalence situations. | 2021-01-14 |
| 33442589 | He was admitted due to these symptoms suggestive of COVID-19, and a chest CT and PCR test confirmed the diagnosis. | 2021-01-14 |
| 33442890 | Diagnosis included: aneurysm (45%), acute aortic syndrome (44%), pseudoaneurysm (4%), aortic valve endocarditis (4%), and other (3%). | 2021-01-14 |
| 33442905 | After the diagnosis of COVID-19, patients were treated according to the most recent recommendations. | 2021-01-14 |
| 33443134 | Diagnostic neurological work-up did not show signs of devastating brain injury. | 2021-01-14 |
| 33443837 | The contribution of several technologies (i.e. virtual reality, actigraphy, computational psychiatry) combining clinical data and neuroscience underlines the great neurobehavioural variability even within the same diagnostic category, calling for greater precision in therapeutic offers as suggested e.g. by developments in neurofeedback. | 2021-01-14 |
| 33444392 | This is a cross-sectional and incidence study carried out on healthcare workers based on molecular and serological diagnosis of SARS-CoV-2 infection. | 2021-01-14 |
| 33444511 | In addition, it highlighted the immunological basis for the new coronavirus 2019 prevention, therapy and diagnosis. | 2021-01-14 |
| 33444833 | Adaptations to surgical techniques included minimising drilling, draping modifications, and using nasal iodine wash. | 2021-01-14 |
| 33444904 | Since many more people are expected to have been infected with this virus without the official diagnosis, the number of people who have recovered from the SARS-CoV-2 infection should be substantial. | 2021-01-14 |
| 33444930 | We assessed the perceived impact of the COVID-19 outbreak, length of isolation, diagnosis/symptoms/hospitalisation related to the COVID-19 (oneself and family). | 2021-01-14 |
| 33445007 | Third, we examine the performance of environmental neurology as a clinical discipline in tropical climates, with focus on the diagnostic and therapeutic challenges posed by human African trypanosomiasis. | 2021-01-14 |
| 33445036 | This would help to provide early diagnosis and reduce contagion by the virus. | 2021-01-14 |
| 33445604 | The non-association with rhinitis symptoms and the high prevalence as a presenting symptom make olfactory disturbances an important symptom in the differential diagnosis between COVID-19 and common flu. | 2021-01-15 |
| 33445727 | One possibility is to expand on existing COVID-19 testing strategies by including large-scale rapid point-of-care diagnostic tests (POCTs). […] In this review, we have used the World Health Organization’s (WHO) recently published target product profiles (TPPs) for specific use cases of COVID-19 diagnostic tests to screen for top-performing POCTs on the market. […] Several POCTs, based on clinical sensitivity/specificity, the limit of detection, and time to results, which meet WHO TPP criteria for direct detection of SARS-CoV-2 (acute infection) or indirect diagnosis of past infection (host antibodies), are highlighted here. | 2021-01-15 |
| 33445821 | We conducted a retrospective cohort study using Korea’s nationwide healthcare database, which contained all individuals who received a diagnostic test for COVID-19 (n=232,390) as of May 15, 2020. | 2021-01-15 |
| 33445824 | From the completely enumerated COVID-19 cohort in Korea, we identified 1,290 patients with hypertension, of whom 682 had and 603 did not have records of ACEI/ARB use during the 30-day period before their COVID-19 diagnosis. | 2021-01-15 |
| 33445940 | To analyse some clinical, diagnostic and therapeutic aspects of Covid-19 in the context of the Czech Republic and to compare them with the data from the most recent literature. […] As soon as new information became available, new diagnostic and therapeutic options were introduced into routine practice. | 2021-01-15 |
| 33445967 | We conducted a convergent mixed method analysis of audience responses to actor Tom Hanks’ March 11, 2020 disclosure of his COVID-19 diagnosis via social media. | 2021-01-15 |
| 33446003 | The prevalence of at least one diagnosis on PHQ-9 is 13.45% (reverse migrants 19.3% and undisplaced 7.6) and the prevalence of other depressive disorder is significantly higher in reverse migrants (17.1%) than undisplaced (4.0%). […] The study concludes that prevalence of mental health issues and substance abuse in migrant population is significantly higher than the general population and the prevalence of at least one diagnosis and other depressive disorder is significantly higher in reverse migrants than undisplaced. | 2021-01-15 |
| 33446311 | The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. […] Its effects on delivery of diagnostic care for cardiovascular disease, which remains the leading cause of death worldwide, have not been quantified. […] The study sought to assess COVID-19’s impact on global cardiovascular diagnostic procedural volumes and safety practices. […] Surveys were submitted from 909 inpatient and outpatient centers performing cardiac diagnostic procedures, in 108 countries. […] COVID-19 was associated with a significant and abrupt reduction in cardiovascular diagnostic testing across the globe, especially affecting the world’s economically challenged. | 2021-01-15 |
| 33446334 | The through-glass technique was quickly implemented, producing diagnostic quality chest radiographs while conserving PPE and reducing risks to radiology staff. | 2021-01-15 |
| 33446945 | As with many other pulmonary conditions, ultrasound may be a better diagnostic tool than routine chest radiography. | 2021-01-15 |
| 33446968 | Demographic profile, clinical, and laboratory variables of 425 patients admitted from April to June 2020 with symptoms and laboratory-confirmed diagnosis through real-time polymerase chain reaction (RT-PCR) were studied. | 2021-01-15 |
| 33447021 | Of the 10,420 patients included in the SEMI-COVID registry as of May 21, 2020, 746 (7.16%) had a diagnosis of COPD. | 2021-01-15 |
| 33447115 | The objective of this study was to investigate the influence of the pandemic on the diagnosis and treatment of sleep-disordered breathing (SDB) in China. […] The questionnaire focused on four main aspects: 1) general information about the centers; 2) changes in SDB management activities, including patient volumes, diagnostic and positive airway pressure (PAP) titration procedures, and follow-up methods, from February to June 2020, compared with before; 3) the application of telemedicine and sleep specialists’ self-assessments of knowledge and their perspectives on telemedicine; and 4) changes in medical staff active in sleep services during the pandemic compared with before. […] Polygraphy played a major role in SDB diagnosis during the pandemic. | 2021-01-15 |
| 33447249 | Data analyses were conducted through descriptive and inferential techniques, with the use of non-parametric tests and linear regression models. | 2021-01-15 |
| 33447639 | The definition of bacterial community-acquired pneumonia (bCAP) included proven (clinical, laboratory, and radiographic criteria plus microbiologic diagnosis), probable (clinical, laboratory, and radiographic criteria without microbiologic diagnosis), and possible (not all clinical, laboratory, and radiographic criteria met) categories. | 2021-01-15 |
| 33447995 | Population: Symptomatic pregnant women with confirmed diagnosis of COVID-19. […] Between the 12th of March and 17th of April 2020, all the symptomatic pregnancies were screened with diagnostic test for SARS-CoV-2. […] Twenty patients with positive COVID-19 diagnostic test out of thirty-four suspected. | 2021-01-15 |
| 33448030 | Evaluate the diagnostic value of cutaneous manifestations of SARS-CoV-2 infection and investigate their duration and timing in relation to other COVID-19 symptoms METHODS: We used data from 336,847 UK users of the COVID Symptom Study app to assess the diagnostic value of body rash or an acral rash in SARS-CoV-2 infection, and data from an independent online survey of 11,546 respondents to investigate skin-specific symptoms and collect their photographs. | 2021-01-15 |
| 33448631 | We included all patients receiving therapeutic anticoagulation for at least 1 month before COVID diagnosis. | 2021-01-15 |
| 33448732 | We do not know the D-dimer increment mechanism in severe patients yet, but we think that these findings will be useful in the early diagnosis of severe disease and the first treatment. | 2021-01-15 |
| 33448734 | This study was carried out to investigate the possible aggravating effect of smoking on the prognosis of patients with COVID-19 pneumonia presenting with pulmonary involvement. 114 adult patients who received inpatient treatment in our clinic with the diagnosis of COVID-19 pneumonia between 11 March 2020 and 30 April 2020 were retrospectively included in the study; in particular, they were evaluated in terms of smoking history, severity of disease, need for NIMV and ICU admission, and mortality during their hospitalization. | 2021-01-15 |
| 33448909 | Currently, several molecular diagnostic platforms such as PCR, qRT-PCR, reverse transcription loop-mediated isothermal amplification (RT-LAMP), CRISPR are utilized for the diagnosis of SARS-CoV-2. […] These conventional techniques are costly, time consuming and require sophisticated instrumentation facility with well trained personnel for testing. […] On the other hand, several serological biosensors such as lateral flow immunosensor, optical, electrochemical, microfluidics integrated electrochemical/fluorescence is currently utilized for the diagnosis of SARS-CoV-2. […] In current pandemic situation, there is an urgent need of rapid and efficient diagnosis on mass scale of SARS-CoV-2 for early stage detection. […] In this review, the SARS-CoV-2 and their biomarkers in biological samples, collection of samples and recently reported potential electrochemical immunosensors for the rapid diagnosis of SARS-CoV-2 are discussed. | 2021-01-15 |
| 33449069 | Nasopharyngeal swab nucleic acid amplification testing (NAAT) is the noninvasive criterion standard for diagnosis of coronavirus disease 2019 (COVID-19). […] Saliva NAAT represents an attractive alternative, but its diagnostic performance is unclear. […] To assess the diagnostic accuracy of saliva NAAT for COVID-19. […] In this systematic review, a search of the MEDLINE and medRxiv databases was conducted on August 29, 2020, to find studies of diagnostic test accuracy. […] The Quality Assessment of Diagnostic Accuracy Studies 2 tool was used to assess the risk of bias. […] These results suggest that saliva NAAT diagnostic accuracy is similar to that of nasopharyngeal swab NAAT, especially in the ambulatory setting. | 2021-01-15 |
| 33449272 | With the diagnosis of the first infected HD case, all other patients who shared the same session were screened. […] COVID-19 diagnosis was made based on clinical, biochemical along radiologic findings. | 2021-01-15 |
| 33449530 | The introduction of the Stroke Platform (SP) in the Belgorod Region to improve the efficiency of diagnosis and care for patients with stroke. | 2021-01-15 |
| 33449840 | Based on the disease course as well as CT-scan findings, a diagnosis of COVID-19 was made. […] Diagnosis of ASSD was eventually retained and immunosuppressive therapy was started. | 2021-01-15 |
| 33449887 | Several studies indicate that lung Computed Tomography (CT) images can be used for a fast and accurate COVID-19 diagnosis. | 2021-01-15 |
| 33449905 | To avoid being caught unprepared by future crises, digital transformation must be further driven to ensure collaboration, and the diagnostic and therapeutic process must be opened to disruptive strategies. | 2021-01-15 |
| 33450165 | Gustatory dysfunction seems to be an understudied symptom of COVID-19 and this may explain the inconsistencies of diagnostic criteria for COVID-19 case definition. […] Furthermore, this diagnostic underestimation can lead to an increased risk of contagion for the whole population and for the working classes most at risk, including the dental one. | 2021-01-15 |
| 33450372 | Serological antibody testing is an important diagnostic method used increasingly in clinics, although its clinical application is still under investigation. […] Tests conducted 2 weeks after symptom onset showed better diagnostic accuracy than tests conducted earlier. […] Chemiluminescence immunoassay and detection of S protein as the antigen could offer more accurate diagnostic results. […] These findings support the supplemental role of serological antibody tests in the diagnosis of COVID-19. | 2021-01-15 |
| 33450533 | The aim of this study is to describe the efficacy and safety outcomes of the virtual training program. ology: A prospective observational cohort study was performed, including patients with diagnosis of T1D previously treated with multiple doses of insulin (MDI) or sensor augmented pump therapy (SAP) who were updating to HCL system, from March to July 2020. | 2021-01-15 |
| 33450670 | The current diagnosis based on nuclear acid requires specialized instruments, time-consuming, and laborious, the low-cost and convenient technologies were still urgently needed. | 2021-01-15 |
| 33450853 |
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2021-01-16 |
| 33450867 | Saline (0.45%) and guanidine hydrochloride have a similar SARS-CoV-2 diagnostic capability as tube additives. | 2021-01-16 |
| 33451000 | In the future, we recommend close monitoring of all patients with skin lesions not attributable to other causal factors; in the diagnostic perspective, clinicians should aim to confirm if the skin lesions are associated with COVID-19. | 2021-01-16 |
| 33451039 | The control over the spread of the disease requires an efficient and scalable laboratory-based strategy for testing the population based on multiple platforms to provide rapid and accurate diagnosis. […] With the onset of the pandemic, the reverse transcription polymerase chain reaction (RT-PCR) method has become a standard diagnostic tool, which has received wide clinical use. […] These are used to assess the level of population immunity in various categories of people, as well as for retrospective diagnosis of asymptomatic and mild COVID-19 in patients. […] However, the widespread use of traditional diagnostic tools in the context of the rapid spread of COVID-19 is hampered by a number of limitations. […] To cope with the COVID-19 pandemic, the healthcare system requires a combination of various types of laboratory diagnostic testing techniques, whodse sensitivity and specificity increases with the progress in the SARS-CoV-2 research. | 2021-01-16 |
| 33451296 | We included patients older than 65 years of age with a diagnosis of COVID-19, from March 2020 to May 2020, divided in two groups according to their age (Elderly: 65-80 years old; Very Elderly > 80 years old). | 2021-01-16 |
| 33451324 | Measles diagnosis was promptly confirmed. | 2021-01-16 |
| 33451352 | A placoid, hyperreflective band at the level of the GCL and IPL was visible in OCT which spared the outer retina, at the time of diagnosis and 1 month later. […] We present a case of COVID-19 diagnosis based on retinal ophthalmic examination. | 2021-01-16 |
| 33451758 | After the diagnosis of COVID-19, MMF was stopped and the tacrolimus dose was reduced so that blood level was between 4 and 6 ng/mL. | 2021-01-16 |
| 33451911 | At that time, the better assessment of the radio-induced malignancies, essentially in children and young patients, as well as the efficacy of the new anti-inflammatory drugs (steroids and non-steroids), led to the almost disappearance of those techniques, at least in France. | 2021-01-16 |
| 33452143 | Elevated LDH has a sensitivity of 0.74 (95% CI 0.60 to 0.85), specificity of 0.69 (95% CI 0.58 to 0.78), positive likelihood ratio of 2.4 (95% CI 1.9 to 2.9), negative likelihood ratio of 0.38 (95% CI 0.26 to 0.55), diagnostic OR of 6 (95% CI 4 to 9) and area under curve of 0.77 (95% CI 0.73 to 0.80). | 2021-01-16 |
| 33452375 | Early diagnosis of viral infection and disease control have always been critical. | 2021-01-16 |
| 33452570 | We reviewed medical records of children with MIS-C diagnosis seen at the Children’s Hospital of Michigan in Detroit between April and June 2020. | 2021-01-16 |
| 33452656 | We collected clinical reports of all consecutive patients admitted with diagnosis of acute ischemic stroke or transient ischemic attack (TIA) during the phase 1 of the lockdown period (11 March 2020-4 May 2020). | 2021-01-16 |
| 33452689 | Therefore, we provide a simplified algorithm of prevention, diagnosis and treatment of severe allergic reactions and a list of recommended medications and equipment for vaccine centres. […] Finally, we identify unmet research needs and propose a concerted international roadmap towards precision diagnosis and management to minimise the risk of allergic reactions to COVID-19 vaccines and to facilitate their broader and safer use. | 2021-01-16 |
| 33452824 | The most common primary diagnosis of 30-day readmission was a hypoxic respiratory failure (68.8%) followed by thromboembolism (12.5%) and sepsis (6.3%). | 2021-01-16 |
| 33452919 | A total of 2579 patients with a positive diagnosis of COVID-19 were identified between March 22 and June 3, 2020 from 18 European hospitals. | 2021-01-16 |
| 33452927 | Successful containment strategies for the SARS-CoV-2 pandemic will depend on reliable diagnostic assays. […] For diagnostic assessment, we used a large set of PCR-positive and PCR-negative respiratory swabs from asymptomatic and symptomatic patients and health care workers in the setting of two University Hospitals in Munich, Germany, i.e. emergency rooms, patient care units or employee test centers. […] For primary diagnosis of asymptomatic and symptomatic individuals, diagnostic sensitivities were 60.9% (FIA) (n = 189) and 64.5% (RAT) (n = 256). | 2021-01-16 |
| 33453023 | Diagnosis of COVID-19 in end-stage kidney disease (ESKD) patients on hemodialysis is challenging, as the symptoms are often atypical. […] SARS-CoV-2 infection was later confirmed by a qualitative RT-PCR test and the diagnosis COVID-19 pneumonia was established. | 2021-01-16 |
| 33453090 | This is a retrospective multihospital cohort study on 1871 patients with confirmed COVID-19 diagnosis. | 2021-01-16 |
| 33453291 | The diagnostic role of oral steroids is discussed and there were some in favour of vitamin A drops. | 2021-01-16 |
| 33453763 | Data were extracted from four population-based datasets spanning NHS England (the National Cancer Cancer Waiting Time Monitoring, Monthly Diagnostic, Secondary Uses Service Admitted Patient Care and the National Radiotherapy datasets) for all referrals, colonoscopies, surgical procedures, and courses of rectal radiotherapy from Jan 1, 2019, to Oct 31, 2020, related to colorectal cancer in England. | 2021-01-17 |
| 33454051 | Machine learning techniques can be leveraged to improve the ability to predict which patients with COVID-19 are likely to require mechanical ventilation, identifying unrecognised bellwethers and providing insight into the constellation of accompanying signs of respiratory failure in COVID-19. | 2021-01-17 |
| 33454317 | Data included 145,936 babies with a CA diagnosis (livebirths, stillbirths and terminations of pregnancy for CA) from 15 population-based EUROCAT registries in 13 European countries, covering 9 million births 1995-2012. | 2021-01-17 |
| 33454365 | Early diagnosis and appropriate treatment are essential in reducing the morbidity and mortality of COVID-19-infected patients. | 2021-01-17 |
| 33454574 | Therefore, the MWSR method can improve the clarity of CT images of COVID-19 and effectively assist the diagnosis and quantitative assessment of COVID-19. | 2021-01-17 |
| 33454928 | COVID-19 can be a precipitating factor in TB respiratory failure and, during ongoing SARS-COV-2 pandemic, clinicians must be aware of this possible co-infection in differential diagnosis of patients with active TB and new or worsening chest imaging. | 2021-01-17 |
| 33454941 | It was discussed that he might have the diagnosis of “mixed anxiety and depression”. | 2021-01-17 |
| 33455138 | In addition to etiology and imaging examination, doctors can also improve the routine laboratory tests such as blood routine test, liver and kidney function to assist diagnosis and disease prediction of patients with respiratory tract infection. | 2021-01-17 |
| 33455218 | The nanostructured surfaces were fabricated using wet-etching techniques which generated nanotextured, randomly aligned ridges approximately 23 nm wide on the Al 6063 alloy surfaces. | 2021-01-18 |
| 33455418 | To describe the profile of advanced cancer inpatients to an exclusive Palliative Care Unit (PCU) with the diagnosis of COVID-19, and to evaluate the factors associated with death in these cases. […] Diagnostic of COVID-19 and death were the dependent variables. […] Eighty-three (53.5%) patients had a diagnostic confirmation of COVID-19. […] Having diabetes mellitus (OR: 2.2; 95% CI: 1.1-6.6) and having received chemotherapy in less than 30 days before admission (OR: 3.8; 95% CI: 1.2-12.2) were associated factors to diagnosis of COVID-19. | 2021-01-18 |
| 33455451 | There is a growing need for data regarding their clinical utility and performance in the diagnosis of SARS-CoV-2 infection in the real life setting of 5 EDs. […] We implemented AGTEST (here: Roche/SD Biosensor) in all four adult and the one pediatric EDs at Charité - Universitätsmedizin Berlin in our diagnostic testing strategy. […] The first swab was collected for nucleic acid testing through SARS-CoV-2 Real-Time Reverse Transcriptase (rt)-PCR diagnostic panel (PCRTEST) in the central laboratory. […] Diagnostic performance was calculated using the PCRTEST as reference standard. | 2021-01-18 |
| 33455920 | All patients who attended our rheumatology outpatient clinic with diagnosis of inflammatory rheumatic disease receiving treatment with biological agents were included. | 2021-01-18 |
| 33455936 | The primary outcome was 30-day mortality from time of first hospital admission with COVID-19 diagnosis during or prior to admission. | 2021-01-18 |
| 33455939 | Participants’ estimates of the SARS-CoV-2 prevalence; the predictive and diagnostic accuracy of the test; the behavioural impact of (positive vs negative) test results; the perceived usefulness of a short-term repetition of the test following positive or negative results; and rankings of causes for false positives and false negatives. […] Most participants considered the swab test useful (89.6%) and provided predictive values consistent with their estimates of test diagnostic accuracy and infection prevalence (67.0%). | 2021-01-18 |
| 33456148 | There are four major types of antibody tests: rapid diagnostic tests, enzyme-linked immunosorbent assays, neutralization assays, and chemiluminescent immunoassays. | 2021-01-18 |
| 33456287 | This paper is in response to the published article entitled “Success, failure and emotions: examining the relationship between performance feedback and emotions in diagnostic reasoning” (Jarrell, Harley, Lajoie, & Naismith, Education Technology & Research Development, 65, 1263-1284: 2017) focusing on its implications to inform educational practice and research as learning and instruction are shifted to digital environments in times of emergencies and crisis. | 2021-01-18 |
| 33456428 | Different fabrication techniques, detection principles, and applications of various pathogens with the electrochemical biosensors were also discussed. | 2021-01-18 |
| 33456433 | We have utilized the latest deep learning techniques such as Long Short Term Memory networks (LSTM), Recurrent Neural Network (RNN), and Gated Recurrent Units (GRU) to quantify the intensity of pandemic for the near future. | 2021-01-18 |
| 33456522 | A brief review of the clinical symptoms of the condition and current diagnostic methods and treatment plans for SARS-CoV-2 are also presented and the progress of preclinical research into medical intervention against SARS-CoV-2 infection are discussed. | 2021-01-18 |
| 33456646 | Its definitive diagnosis is made by PCR on nasopharyngeal swabs. […] However, this diagnostic test has low sensitivity with delayed results. | 2021-01-18 |
| 33456651 | Diagnosis was based on nasal and nasopharyngeal swab positive result of reverse transcriptase-polymerase chain reaction (RT-PCR) result. | 2021-01-18 |
| 33456652 | All children stayed in the isolation center for 14 days and were re-tested for COVID-19 two weeks after initial diagnosis. […] This has significant implication on the diagnosis of COVID-19 in malaria-endemic settings and on how best to manage children who present with fever during the COVID-19 pandemic. | 2021-01-18 |
| 33456658 | So in this case report, we intend to discuss the possible impact of the current COVID-19 pandemic on patients with acute leukaemia in terms of diagnosis, chemotherapy, and prophylactic measures. | 2021-01-18 |
| 33456721 | However, for the treatment and diagnosis of various lung diseases, such as pneumonia, asthma, cancer, and pulmonary tuberculosis, are becoming increasingly challenging. […] Currently, several types of treatments and/or diagnostic methods are used to treat lung diseases; however, the occurrence of adverse reactions to chemotherapy, drug-resistant bacteria, side effects that can be significantly toxic, and poor drug delivery necessitates the development of more promising treatments. […] In recent years, nanotechnology has provided a feasible platform for improving the diagnosis and treatment of diseases, nanotechnology-based strategies may have broad prospects in the diagnosis and treatment of COVID-19. | 2021-01-18 |
| 33457109 | Here, we summarise details of the SARS-CoV-2 genome to assist understanding of the emergence, evolution and diagnosis of this deadly new virus. […] Importantly, current diagnosis requires specific recognition and amplification of the SARS-CoV-2 RNA genome by qPCR, despite these ongoing viral genome changes. […] Alternative diagnostic procedures relying on immunoassay are becoming more prevalent. | 2021-01-18 |
| 33457115 | Concerning the barriers to telemedicine, the ones having the most concordance were technological limitations (66.6%) and concerns of diagnostic reliability (66.1%). […] The responses from our study seem to suggest that while the attitudes toward telemedicine are positive, practicing physicians are concerned about a perceived lack of clarity regarding related legal frameworks and barriers such as technological issues, cultural factors, and diagnostic concordance. | 2021-01-18 |
| 33457170 | The goals include safely use as potential prophylactic or therapeutic treatments, based on in silico and in vivo studies, including clinical trials around the world for the correct and timely diagnosis of the infection. | 2021-01-18 |
| 33457174 | The AI technology strategies and framework is highlighted in terms of bulk data computing, predicting infection threats, providing medical assistance, and analyzing diagnosis results. | 2021-01-18 |
| 33457307 | It also has introduced great challenges to the diagnosis and management of children with hepatoblastoma (HB). […] During the COVID-19 pandemic, pediatric surgeons should not only develop personalized treatment plans for HB therapy, but also emphasize the diagnosis, prevention, and treatment of this virus. | 2021-01-18 |
| 33457355 | The initial presumptive diagnosis was of severe coronavirus illness. […] This case report highlights the importance of keeping an open mind to alternative diagnoses and examines some of the challenges in the diagnosis and management of a rare condition in the pandemic environment. | 2021-01-18 |
| 33457377 | The course was complicated by the classic pentad of thrombocytopenia, intravascular haemolysis, acute kidney injury, neurological symptoms and fever, which prompted the diagnosis of probable TTP. […] The potential role of plasma exchange in COVID-19 patients without a positive diagnosis of TTP (the so-called ‘TTP resembling presentation’) is an area of further research. | 2021-01-18 |
| 33457379 | We report the case of a young man admitted with a diagnosis of COVID-19 pneumoniae with PH unrelated to viral infection and in whom partial anomalous pulmonary venous drainage (PAPVD) was eventually diagnosed. | 2021-01-18 |
| 33457446 | The heatmap and confidence score of the detection are also demonstrated, such that users or human experts can use them for a final diagnosis in practical usages. | 2021-01-18 |
| 33457490 | Our data suggest the assessment of high sensitivity cardiac troponin in patients with COVID-19 for early diagnosis of cardiac involvement. | 2021-01-18 |
| 33457507 | A positive diagnosis for COVID-19 is a threat not only to the health of an individual but also to the community where the disease manifests. | 2021-01-18 |
| 33458451 | Despite many radiation oncologists having little prior experience with tele-consultations, a majority were satisfied in being able to explain the details of a medical diagnosis, provide results of imaging and bloodwork, and discuss recommendations around radiation treatments through this format. | 2021-01-18 |
| 33458567 | The time interval from the symptom onset to TTS diagnosis was median 6.5 days (IQR: 1.0-8.0) in case series and 6.7 days (IQR: 4-10) in individual patients’ database. | 2021-01-18 |
| 33458687 | This was a retrospective cohort study of 39 adult patients admitted to the ICU with a confirmed coronavirus disease 2019 diagnosis at a large tertiary-care academic medical center. | 2021-01-18 |
| 33458689 | In recent times, patient care in ICUs has become more complex with technological advances in monitoring, diagnostic testing, and therapeutics; many of these advances have translated into improved patient outcomes. | 2021-01-18 |
| 33458811 | Of almost 59K donors registering on the website, 75% reported an existing COVID-19 diagnostic PCR or an antibody test. | 2021-01-18 |
| 33459685 | Chest X-ray imaging has been proved as a powerful diagnostic method to detect and diagnose COVID-19 cases due to its easy accessibility, lower cost and rapid imaging time. […] This study demonstrated that the proposed CNN model called nCoV-NET can be utilized for reliably detecting COVID-19 cases using chest X-ray images to accelerate the triaging and save critical time for disease control as well as assisting the radiologist to validate their initial diagnosis. | 2021-01-18 |
| 33459907 | The diagnostic performance of the algorithm was assessed by comparing results on a test set of 1885 images. | 2021-01-18 |
| 33460428 | Kidney infarction cases require high diagnostic suspicion and possibility of starting anticoagulation. | 2021-01-18 |
| 33460503 | Investigated experiences included exposure to COVID-19-related news, having being in close proximity to people with a COVID-19 diagnosis or with COVID-19-like symptoms, having being sick or having suffered COVID-19-like symptoms, having tested negative for COVID-19. […] Perceived stigma was also directly and negatively related to hedonic and eudaimonic well-being, whereas having tested negative for COVID diagnosis was positively and directly associated with eudaimonic well-being. | 2021-01-18 |
| 33461214 | Clinical testing for antibodies to SARS-CoV-2 has rapidly become widespread, but data regarding the inter-laboratory performance of these serologic assays are limited. - To describe the development and initial results of the College of American Pathologists (CAP) SARS-CoV-2 Serology Survey. - Members from the CAP Microbiology and Diagnostic Immunology and Flow Cytometry Committees formed a working group to support development of a new proficiency testing survey for anti-SARS-CoV-2 antibody assays. | 2021-01-18 |
| 33461602 | Confirmed diagnosis of SARS-CoV-2 infection based on polymerase chain reaction (PCR) of nasopharyngeal secretions or clinical manifestations along with chest computed tomography (chest CT) scan 2. | 2021-01-19 |
| 33461632 | Seventeen per cent had D-dimer values two times above the threshold for diagnosis of pulmonary embolism (two unexpected and clinically silent pulmonary thrombosis were discovered by investigating striking D-dimer elevation). | 2021-01-19 |
| 33461641 | There may be value in promoting these techniques more widely in the community to manage general distress during such times. | 2021-01-19 |
| 33461715 | The COVID-19 global pandemic of 2019-2020 pointedly revealed the lack of diagnostic solutions that are able to keep pace with the rapid spread of the virus. […] In this critical review, we assess the current state of progress on the development of point-of-care technologies for the diagnosis of viral diseases that cause pandemics. […] First, we recommend a set of requirements to heed when designing point-of-care diagnostic technologies to address the testing needs of a pandemic. | 2021-01-19 |
| 33461842 | The etiological diagnosis of bronchopulmonary infections cannot be assessed with clinical, radiological and epidemiological data alone. […] The diagnosis of viral bronchopulmonary infections is based on the analysis of secretions, collected from the lower respiratory tract when possible, by techniques that detect either influenza and respiratory syncytial viruses, or a large panel of viruses that can be responsible for respiratory disease. […] The availability of new diagnostic technologies, the recent emergence of SARS-CoV-2, together with the availability of new antiviral drugs are likely to impact future recommendations for the management of viral bronchopulmonary infections. | 2021-01-19 |
| 33461849 | ) of IgG antibody (CR3022) to SARS-CoV-2 in human serum samples, demonstrating the efficacy of these devices for COVID-19 diagnosis. […] This work provides a methodology for the rational design of high-performance EIS μPADs and has the potential to facilitate diagnosis in pandemics. | 2021-01-19 |
| 33461859 | Information on patient age, gender, and surgical diagnosis, site, and procedure was collected for cases operated on in each period. | 2021-01-19 |
| 33461884 | Accurate diagnostic testing to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical. […] This study seeks to explore whether the integration of lung ultrasonography with clinical evaluation is associated with increased sensitivity for the diagnosis of coronavirus disease 2019 pneumonia, and therefore may facilitate the identification of false-negative SARS-CoV-2 RT-PCR results. | 2021-01-19 |
| 33462068 | In keeping with a diagnosis of Guillain-Barré syndrome, cerebrospinal fluid examination showed albuminocytologic dissociation and nerve conduction studies supported the diagnosis of an acute inflammatory demyelinating polyradiculoneuropathy. | 2021-01-19 |
| 33462118 | Of those who accessed SHS, 28% reported an STI diagnosis. | 2021-01-19 |
| 33462560 | Deep learning-based time series techniques are considered to predict world-wide COVID-19 cases in advance for short-term and medium-term dependencies with adaptive learning. | 2021-01-19 |
| 33462561 | The skilled techniques of disinfection, sanitization, and other viable wayouts are to be modified with time, place, and prevailing climatic conditions, handling the pandemic efficiently. | 2021-01-19 |
| 33462565 | We discuss in depth factors related to this woman’s care, such as appropriate assessment and evaluation of early medical abortion cases, the diagnostic challenges of early pregnancy scanning as well as the implications of the COVID-19 pandemic on the provision of care in these scenarios, and how this affected this woman’s care. | 2021-01-19 |
| 33463126 | For introducing a factor as a diagnostic/prognostic biomarker, diagnostic test accuracy (DTA) systematic review and meta-analysis are recommended. […] Pooled-diagnostic odds ratios were 6.78 (95% CI, 3.65-12.61) for prognosis of critical condition and 13.21 (95% CI, 3.95-44.19) for mortality. | 2021-01-19 |
| 33463566 | Diagnosis of mucormycosis was based on clinical features, culture, and histopathology from sinus biopsy. […] The mean duration between diagnosis of COVID-19 and development of symptoms of mucor was 15.6 ± 9.6 (3-42) days. […] High index of suspicion, early diagnosis, and appropriate management can improve survival. | 2021-01-19 |
| 33463719 | A key aspect in limiting the virus diffusion is to ensure early and accurate diagnosis. […] The aim of this study was to evaluate the diagnostic accuracy of a second generation chemiluminescent automated immunoassay able to detect anti-SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies. | 2021-01-19 |
| 33463960 | In this article, we describe different types of diagnostic tests currently used to detect SARS-CoV-2 infection. […] This article also provides an insight into various supplementary diagnostic modalities, including recent advancements in sensing technologies and further clinical improvement and novelties to fight this pandemic. | 2021-01-19 |
| 33464400 | COVID-19 polymerase chain reaction (PCR) was the diagnostic standard. | 2021-01-19 |
| 33464429 | APLs are assessed for anti-phospholipid syndrome (APS) diagnosis, characterized by thrombocytopenia, thrombosis, and coagulopathy. | 2021-01-19 |
| 33464917 | Specifically, we discuss how (1) mass spectrometry-based structural techniques can overcome limitations and complement traditional structural approaches to inform the dynamic structure of SARS-CoV-2 proteins, complexes, and virions; (2) virus-host protein-protein interaction mapping can identify the cellular machinery required for SARS-CoV-2 replication; (3) global protein abundance and post-translational modification profiling can characterize signaling pathways that are rewired during infection; and (4) proteomic technologies can aid in biomarker identification, diagnostics, and drug development in order to monitor COVID-19 pathology and investigate treatment strategies. | 2021-01-19 |
| 33465012 | Presence of co-morbidities, diagnostic values, and clinical findings. | 2021-01-19 |
| 33465033 | A 15-item questionnaire was designed including different sections as follows: demographics, diagnostic characteristics, STD patterns, medication use as well as comorbidities. | 2021-01-19 |
| 33465426 | Although clinical trials are needed to determine the efficacy of both drugs in the treatment of COVID-19, this analysis suggests that primary care diagnosis and treatment with antihistamines, plus azithromycin in selected cases, may treat COVID-19 and prevent progression to severe disease in elderly patients. | 2021-01-19 |
| 33465496 | Data was collected from all patients (≥16 years) with a diagnosis of AA between November 1, 2019 to March 10, 2020 (pre-COVID period) and March 10, 2020 to July 5, 2020 (COVID period). […] Radiological diagnosis of AA was more frequent during the COVID period. | 2021-01-19 |
| 33465590 | Screening and diagnostic assessments tools for autism spectrum disorder (ASD) are important to administer during childhood to facilitate timely entry into intervention services that can promote developmental outcomes across the lifespan. […] Currently, in-person screening and diagnostic assessments for ASD are limited due to the COVID-19 pandemic and will continue to be a concern for situations that limit in-person contact. | 2021-01-19 |
| 33465784 | Oro- and nasopharyngeal swab specimens by quantitative reverse-transcriptase polymerase chain reaction (RT-PCR) to detect SARS-CoV-2 is currently the main diagnostic tool during the ongoing COVID-19 pandemia. | 2021-01-19 |
| 33466265 | The following inclusion criteria were observed: age at the time of diagnosis less than 30 months, absence of other neurological, genetic, or sensorineural pathologies, and severity level 1 measured by symptoms evaluation based on the ADOS 2 module T (used for diagnosis). | 2021-01-20 |
| 33466537 | Due to the steadily rising case numbers of SARS-CoV-2 infections worldwide, there is an increasing need for reliable rapid diagnostic devices in addition to existing gold standard PCR methods. […] Actually, public attention is focused on antigen assays including lateral flow tests (LFTs) as a diagnostic alternative. | 2021-01-20 |
| 33466884 | The importance of a timely and accurate diagnosis is essential to determine the course of the pandemic. […] Further, a broader perspective of the correct use and interpretation of the results obtained with these diagnostic tools is proposed to improve the containment strategy and identify the true impact of the pandemic. | 2021-01-20 |
| 33466948 | Little is known about how people with dementia and/or their family carers access health and social care services after a diagnosis. […] Four themes emerged from the interviews: (1) Getting the ball rolling: the process of diagnosis; (2) Balancing the support needs of people with dementia and carers; (3) Barriers to accessing support; and (4) Facilitators to accessing support. […] People with YOD and LOD and their carers require better support in accessing services after a diagnosis. | 2021-01-20 |
| 33467501 | A nasopharyngeal swab is a sample used for the diagnosis of SARS-CoV-2 infection. […] This study aimed to evaluate the utility of saliva for the diagnosis of SARS-CoV-2 infection. […] In conclusion, saliva sample utility is limited for clinical diagnosis, but could be a useful alternative for the detection of SARS-CoV-2 in massive screening studies, when the availability of trained professionals for sampling or personal protection equipment is limited. | 2021-01-20 |
| 33467761 | Besides, with an obvious parallel to clinical diagnostic practice, such imaging platforms are potent and valuable instruments leading to a more refined use of animals from a welfare perspective. | 2021-01-20 |
| 33467861 | We analyzed how the healthcare restrictions that occurred in hospitals in Spain due to the COVID-19 pandemic, mainly in March, April and May 2020, influenced the diagnosis, management and treatment of ulcerative colitis (UC) in our center. | 2021-01-20 |
| 33467990 | Here we hope to have contributed to its possible amelioration with highlights of the latest thinking on neglect diagnosis, prevalence and treatment. | 2021-01-20 |
| 33468160 | These abilities make the nanozymes suitable for multiple applications in sensing and imaging, tissue engineering, environmental protection, satisfactory tumor diagnostic and therapeutic, because of distinguished properties compared with other artificial enzymes such as high biocompatibility, low toxicity, size dependent catalytic activities, large surface area for further bioconjugation or modification and also smart response to external stimuli. | 2021-01-20 |
| 33468242 | Patients were under the age of 18 and had a diagnosis of an eating disorder. | 2021-01-20 |
| 33468435 | To analyse the diagnostic performance of eosinopenia, alone or combined with polymorphonuclear neutrophils (PMN) and/or lymphocytes, as a marker of active COVID-19 in patients hospitalized for suspicion of SARS-CoV-2 infection. […] Patients for which there was a doubt upon diagnosis, who were recently under oral corticosteroids, had myeloid malignancy or human immunodeficient virus infection were excluded. | 2021-01-20 |
| 33468605 | Accurate diagnosis of acute severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection is critical for appropriate management of patients with this disease. […] We analyzed the influence of timing and clinical severity on the diagnostic value of class-specific coronavirus disease 2019 (COVID-19) serology testing. […] Our findings suggest the potential utility of IgA serology in the acute setting and explore the benefits and limitations of class-specific serology as a complementary diagnostic tool to PCR for COVID-19 in the acute setting. | 2021-01-20 |
| 33469083 | A test-and-isolate strategy, using PCR diagnostic tests, could help to minimise the impact of this second wave. | 2021-01-20 |
| 33469377 | During this trying time, patients with ovarian cancer (OC) have been affected by a delay in diagnosis, surgery, chemotherapy and radiation treatments, and oncology follow-ups being conducted via telemedicine instead of in-person visits. […] In this article, we succinctly review the impact of the COVID-19 pandemic on the diagnosis and treatment and ongoing clinical trials of OC. | 2021-01-20 |
| 33469467 | In this study, a new COVID-19 diagnosis strategy called Feature Correlated Naïve Bayes (FCNB) has been introduced. […] The proposed FCNB strategy has been compared to recent competitive techniques. […] Experimental results have proven the effectiveness of the FCNB strategy in which it outperforms recent competitive techniques because it achieves the maximum (99%) detection accuracy. | 2021-01-20 |
| 33469560 | Later, they make recommendations on the stabilisation, diagnosis, and treatment of this syndrome. | 2021-01-20 |
| 33469649 | The correct diagnosis of viral diseases represents a crucial step towards effective treatments and control. […] Additionally, we explore this methodology in a case study for the detection of highly pathogenic coronaviruses that share the same cell receptor upon infection (i.e. the Angiotensin-Converting Enzyme 2, ACE2), as a conceptual example of the potential of the GPCR/YSD strategy for the diagnosis of COVID-19. | 2021-01-20 |
| 33470070 | Knowledge of diagnostic methods is continuously evolving, so it is crucial to understand the nature of the tests and to be able to interpret their results. […] This review discusses the current literature on diagnostic methods, prognostic markers, diagnostic recommendations, choice of the appropriate test, type of biological material, and interpretation of results depending on test sensitivity and disease duration. […] Further development of diagnostic techniques and incorporation of new technologies can provide more accurate and faster tools for control the epidemic. | 2021-01-20 |
| 33470072 | Molecular diagnostic methods, including real-time reverse transcription-PCR (RT-PCR) assay are the recommended methods for the identification and laboratory confirmation of COVID-19 cases. […] In response to demand of a molecular diagnostic test for SARS-CoV-2, within a first few months ongoing pandemic many commercial kits has become available on the market. | 2021-01-20 |
| 33470437 | Investigate factors that influence the decision to accept or decline diagnostic testing for pregnant women referred for genetic counseling. […] There were no differences in sociodemographic factors between women undergoing a diagnostic procedure compared to those not undergoing a procedure. […] As the perceived risk for having a baby with genetic problem increased by one point, the estimated odds of having the diagnostic procedure increased by 43% controlling for the perceived risk of procedure related loss (p < .0001). […] Similarly, as the perceived risk of miscarriage increased by one point, the odds of having the diagnostic procedure decreased by 40%, controlling for the perceived risk of having a baby with a genetic problem (p < .0001). […] Pregnant women that decline diagnostic testing have a higher perceived risk of procedure related loss and lower perceived risk of fetal chromosomal abnormality than those who accept. | 2021-01-20 |
| 33470800 | The flexible fabric substrate, the sponge-like porous architecture of the high-efficiency sol-gel sorbent coating, the availability of a large cache of sorbent coatings, including polar, nonpolar, mixed mode, and zwitterionic phases, the easy installation into the facemask, and the possibility of sampling without interrupting regular activities provide FPSMs unparalleled advantages over other sampling techniques, and their applications are expected to expand to many other clinical or toxicological studies. | 2021-01-20 |
| 33470830 | In patients with tinnitus, one of the most important diagnostic element is medical history data. […] The knowledge about the patient’s hearing condition before contracting COVID-19, the early symptoms of SARS-CoV-2 infection, the method of diagnosis of the infection, the time and method of isolation of the patient, and the time from the diagnosis of COVID-19 to the appearance of otolaryngological symptoms might enable the reader to gain more knowledge on the correlation between COVID-19 and tinnitus. | 2021-01-20 |
| 33470952 | Coronavirus disease (COVID-19) blindness, that is, the excessive consideration of the disease in diagnosis, has reportedly led to delayed diagnosis of some diseases. […] Our findings suggested that due to the COVID-19 epidemic/pandemic, focusing on the exclusion of its infection using CT scans leads to an overall delay in the diagnosis and treatment of bacteremia. | 2021-01-20 |
| 33471219 | To identify subgroups of patients where artificial intelligence (AI) can be of particular value and analyse what imaging features may have contributed to the performance of AI by means of visualisation techniques. | 2021-01-20 |
| 33471349 | Iidiopathic pulmonary fibrosis (IPF) diagnosis and treatment during this COVID-19 pandemic have been affected. | 2021-01-20 |
| 33471350 | So, this study was planned to validate the diagnostic accuracy of the ROX index for prediction of COVID-19 pneumonia outcome (the need for intubation) and, in addition, to underline the significant association of the ROX index with clinical, radiological, demographic data. | 2021-01-20 |
| 33471512 | An efficient diagnostic method must be highly accurate, while having a cost-effective profile. […] The method applied for COVID-19 diagnosis showed specificity >96% and sensitivity >83%, and specificity >80% and sensitivity >85% during risk assessment, both from blinded data. | 2021-01-20 |
| 33471720 | COVID-19 could be associated with worsening diabetes control and new diabetes diagnosis that could be linked to high expression of angiotensin-converting enzyme 2 (ACE2) receptors (coronavirus point of entry into the host) in the endocrine pancreas. | 2021-01-20 |
| 33471776 | Anxiety and depression were assessed using the 2-item Generalized Anxiety Disorder scale (GAD-2) and 2-item Patient Health Questionnaire (PHQ-2), and scores ≥3 indicated a clinical diagnosis of anxiety or depression, respectively. | 2021-01-20 |
| 33472036 | This study aimed to validate two serologic tests for total (IgM, IgG, IgA) SARS-CoV-2 antibodies, (i) the Ortho-Clinical Diagnostics Anti-SARS-CoV-2 Total Antibody assay for the Vitros 5600 analyzers and (ii) a manual laboratory developed ELISA (FDA EUA pending), for use in parallel orthogonal testing of asymptomatic healthcare workers and affiliates of the University of Maryland Medical System. | 2021-01-20 |
| 33472127 | One hundred and eighty five patients were admitted during the total period of observation with the diagnosis of ACS. | 2021-01-20 |
| 33472638 | Lockdowns can be an effective pandemic response strategy that can buy much needed time to slow disease transmission and adequately scale up preventative, diagnostic, and treatment capacities. | 2021-01-21 |
| 33472790 | Records from the Argentine Integrated Health Reporting System for all persons with suspected and RT-PCR-confirmed diagnosis of COVID-19 between 31 January and 14 July 2020. | 2021-01-21 |
| 33474768 | They were scanned after a median of 32 days (IQR 22-62 days) from the diagnosis. […] Diagnosis of acute myocarditis was based on modified Lake Louise criteria. […] We have shown that in a small group of elite athletes with mainly asymptomatic to mild Covid-19, lack of electrocardiographic changes, and normal troponin concentration 1-2 months after the diagnosis, there were no signs of acute myocarditis, but 19% of athletes had some abnormalities as assessed by cardiac MR. | 2021-01-21 |
| 33474816 | We conducted an observational, monocentric, prospective study of patients with a COVID-19 diagnosis hospitalized during the 3-month period of the first wave of the COVID-19 pandemic in a tertiary hospital in Madrid (Spain). | 2021-01-21 |
| 33475019 | For this purpose, a rapid alternative diagnostic choice to prevent COVID-19 spread among individuals must be implemented as an automatic detection method. | 2021-01-21 |
| 33475159 | Co-infection with influenza A virus (IFV-A) during the upcoming flu season may complicate diagnosis and treatment of COVID-19. | 2021-01-21 |
| 33475217 | Median length-of-stay, 30-day mortality and admission diagnosis were comparable. | 2021-01-21 |
| 33475330 | Misdiagnosis and delayed diagnosis are common problems in healthcare and are typically related to patient, provider, and socioeconomic factors. | 2021-01-21 |
| 33475683 | Further studies are required to determine specific diagnostic capabilities in various telehealth practice settings. | 2021-01-21 |
| 33476063 | A variable and a minimal amount of data are available for the signs and symptoms of Covid-19, allowing a composite of maximum likelihood algorithms to be employed to enhance the accuracy of disease diagnosis and to identify potential drugs. | 2021-01-21 |
| 33476080 | The advent of the loop-mediated isothermal amplification (LAMP) assay provided an innovative tool for establishing a rapid diagnostic technique based on the molecular amplification of pathogen RNA or DNA. […] In this review, we explore the applications, diagnostic effectiveness of LAMP test for molecular diagnosis and surveillance of severe acute respiratory syndrome coronavirus 2. […] Our results show that LAMP can be considered as an effective point-of-care test for the diagnosis of Covid-19 in endemic areas, especially for low- and middle-income countries. | 2021-01-21 |
| 33476193 | The summit consisted of five sessions: (I) Keynotes, (II) Preparedness, (III) Response, (IV) Recovery, and (V) Surveillance; eight parts: (A) Background, (B) Resilience, (C) Outpatient Care, (D) Inpatient Care, (E) Resources, (F) High-Risk Groups, (G) Regulation, and (H) The Future; and 24 sections: (1) Historic Pandemics and Impact on Society, (2) Pathophysiology/Risk Factors for COVID-19, (3) Social Determinants of COVID-19, (4) Preparing for the Future, (5) Medications and Vaccines, (6) Psychology of Patients and Caregivers, (7) Outpatient Treatment of Diabetes Mellitus and Non-Pharmacologic Intervention, (8) Technology and Telehealth for Diabetes Outpatients, (9) Technology for Inpatients, (10) Management of Diabetes Inpatients with COVID-19, (11) Ethics, (12) Accuracy of Diagnostic Tests, (13) Children, (14) Pregnancy, (15) Economics of Care for COVID-19, (16) Role of Industry, (17) Protection of Healthcare Workers, (18) People with Diabetes, (19) International Responses to COVID-19, (20) Government Policy, (21) Regulation of Tests and Treatments, (22) Digital Health Technology, (23) Big Data Statistics, and 24) Patient Surveillance and Privacy. | 2021-01-21 |
| 33476707 | Facing the ongoing pandemic caused by SARS-CoV-2, there is an urgent need for serological assays identifying individuals previously infected by coronavirus disease 2019 (COVID-19), including rapid diagnostic tests (RDTs). | 2021-01-21 |
| 33476761 | While musculoskeletal symptoms were not associated with developing a pneumonia, to avoid missing a diagnosis of COVID-19, clinicians should be aware of its variable onset, particularly when respiratory symptoms are absent at the time of presentation. | 2021-01-21 |
| 33476975 | The patients with OTD had a lower Ct value at diagnosis, and hence, a higher viral load than those without OTD. | 2021-01-21 |
| 33477522 | Furthermore, answers regarding the clinical picture, diagnostic approach, and treatment options are discussed. | 2021-01-22 |
| 33478188 | At present, although combined imaging, serology, genomics, proteomics and other methods have been combined to screen for suspected lung cancer, there are still problems such as missed diagnosis and misdiagnosis. | 2021-01-22 |
| 33478237 | This review provides a brief synopsis regarding the molecular biology, pathology and laboratory tests commonly used in the diagnosis and prognosis of covid-19, as well as the development of vaccines and therapeutic strategies to manage its current and future mutations. | 2021-01-22 |
| 33478499 | Most proposals focused on the development and innovation of personal protective equipment, medical devices, diagnostic tests, medicines and vaccines, which were rapidly identified as research priorities by the scientific community. | 2021-01-22 |
| 33478655 | Myocarditis is an uncommon pathologic diagnosis occurring in 4.5% of highly selected cases undergoing autopsy or endomyocardial biopsy. | 2021-01-22 |
| 33478743 | Due the COVID-19 pandemic, several restrictive measures have been implemented by the State federation’s governments, and cancer diagnosis reference centers were also impacted by these measures. […] Thus, this study aimed to compare SUS-oriented cancer diagnosis in Brazil before and during the pandemic so far. […] The pandemic period has dramatically reduced the diagnosis of new cases of cancer in Brazil, since consultations in public health services were compromised by restrictive measures. | 2021-01-22 |
| 33479021 | Most frequent diagnosis was rheumatoid arthritis, RA (48%). 29% of the patients were hospitalised, 5.5% needed ventilation. 19 patients died. | 2021-01-22 |
| 33479073 | The case highlights how the COVID-19 pandemic can create new challenges in the diagnosis of GPA. | 2021-01-22 |
| 33479162 | The most common diagnostic test was detection of viral RNA by polymerase chain reaction of nasopharyngeal swabs at a median age of 3 hours after delivery (1-12 hours). | 2021-01-22 |
| 33479795 | COVID-19 will continue to disrupt the diagnosis-treatment process of cancer patients. […] The patients admitted to the medical oncology follow-up, new diagnosis, or chemotherapy (CT) outpatient clinics during the first quarter of pandemic period (March 15-June 1, 2020) of each center were determined and compared with the admissions of the same frame of previous year (March 15-June 1, 2019). […] The number of patients admitted new diagnosis outpatient clinics in both clean and pandemic hospitals decreased significantly during the pandemic compared with the previous year. | 2021-01-22 |
| 33479801 | However, in a minority of cases, a clinical picture with symptoms fulfilling criteria for MIS-C diagnosis develops during the acute phase of SARS-CoV-2 infection. | 2021-01-22 |
| 33480019 | Diagnosis of SARS-CoV-2 infection is a major public health issue. […] In a context of limited diagnostic capacity with the reference technique (real-time RT-PCR), many manufacturers have developed rapid diagnostic tests (RDTs). […] TDRs based on antibody detection are not appropriate for the early diagnosis of COVID-19. […] However, validated and specific tests could provide complementary diagnostic information to reference tests. | 2021-01-22 |
| 33480020 | The clinician is required to know this type of manifestations in order to limit the delay in diagnosis and to better assess the prognosis. | 2021-01-22 |
| 33480338 | Recent outburst of disease COVID-19 (nCoV19) is a recent example wherein effective management of virus using conventional medication or adopting preventive and effective diagnostic measures is a challenge. […] While many ongoing strategies from vaccine development to drug repurposing, are currently being investigated, a targeted approach with nanotechnology can be helpful to meet the demand for preventive and diagnostic measures. […] The significant results of nanotechnology in resolving better efficacy in pharmaceutical drugs is expected to be helpful in combating nCoV19 by using nanotechnology-based solutions preventive, treatment, and diagnosis. […] Multiple applications of nanotechnology is expected to be helpful in preventive and diagnostic measures, immune response modulation and immunity boosters along with projecting a pathway for industry and academic researchers for addressing such pandemic. | 2021-01-22 |
| 33480349 | A paradigm shift was observed globally as the world’s emphasis shifted to testing, diagnosis, treatment, and developing a coronavirus cure. | 2021-01-22 |
| 33480553 | The index case was anesthetized for diagnostic workup. […] This case series describes the clinical presentation, diagnostic evaluation, and management of tigers and lions infected with SARS-CoV-2 and describes the duration of viral RNA fecal shedding in these cases. | 2021-01-22 |
| 33480807 | Coagulopathy in COVID-19, showing mixed features of complement-mediated and consumption coagulopathy, creates a dilemma in diagnosis and management. | 2021-01-22 |
| 33480973 | Accurate molecular diagnostic tests are necessary for confirming a diagnosis of coronavirus disease 2019 (COVID-19). […] The numbers of available SARS-CoV-2 nucleic acid detection tests are rapidly increasing, as is the COVID-19 diagnostic literature. […] The IDSA’s goal was to develop an evidence-based diagnostic guideline to assist clinicians, clinical laboratorians, patients and policymakers in decisions related to the optimal use of SARS-CoV-2 nucleic acid amplification tests. […] In addition, we provide a conceptual framework for understanding molecular diagnostic test performance, discuss the nuance of test result interpretation in a variety of practice settings and highlight important unmet research needs in the COVID-19 diagnostic testing space. […] The panel agreed on 17 diagnostic recommendations. […] Recognizing these limitations, the IDSA panel weighed available diagnostic evidence and recommends nucleic acid testing for all symptomatic individuals suspected of having COVID-19. | 2021-01-22 |
| 33481202 | This retrospective, single-center study was performed to systemically describe the characteristics and outcomes of patients with severe and critical coronavirus disease 2019 (COVID-19) in Wuhan, analyze the risk factors, and propose suggestions for clinical diagnosis and treatment to guide the subsequent clinical practice. | 2021-01-22 |
| 33481314 | As these skin lesions may have a possible association with diagnosis, management, prognosis, and severity of the disease, all health practitioners need to be well acquainted with these Covid-19 skin lesions. | 2021-01-22 |
| 33481726 | We describe the creation of the NIVSU, the health professional-patient ratio, the type of room, the modified personal protection equipment; diagnostic, monitoring and ventilatory support equipment for treatment, as well as the inclusion criteria and the treatment algorithm. | 2021-01-22 |
| 33481731 | For diagnosis, more than one reverse transcriptase polymerase chain reaction (RT-PCR) sample was needed in 24% of cases. | 2021-01-22 |
| 33481732 | We aim to describe the diagnostic yield of early blood cultures in patients with COVID-19 pneumonia in a public hospital in Buenos Aires City. | 2021-01-22 |
| 33481900 | Of the 747 (14.5%) participants reporting COVID-19-like symptoms, 367 (49.1%) obtained a diagnostic test. | 2021-01-22 |
| 33481990 | To understand the impact on resource and service utilisation, techniques of quality improvement should be implemented, and appropriate metrics reflecting both process and outcome will be essential to underpin robust and sustainable business cases to support implementation of delirium care as a long-term solution. | 2021-01-22 |
| 33482113 | All patients-irrespective of age, diagnosis, donor type, graft source, or conditioning regimens-were included in the analysis with data cutoff of Aug 12, 2020. […] The main outcome was overall survival 30 days after a COVID-19 diagnosis. […] Factors associated with mortality after COVID-19 diagnosis were examined using Cox proportional hazard models. […] The median time from HSCT to COVID-19 diagnosis was 17 months (IQR 8-46) for allogeneic HSCT recipients and 23 months (8-51) for autologous HSCT recipients. […] The median follow-up of survivors was 21 days (IQR 8-41) for allogeneic HSCT recipients and 25 days (12-35) for autologous HSCT recipients. 34 (18%) of 184 allogeneic HSCT recipients were receiving immunosuppression within 6 months of COVID-19 diagnosis. […] At 30 days after the diagnosis of COVID-19, overall survival was 68% (95% CI 58-77) for recipients of allogeneic HSCT and 67% (55-78) for recipients of autologous HSCT. | 2021-01-22 |
| 33482115 | Assess diagnostic radiology examination utilization and associated social determinants of health during the early stages of reopening after state-mandated shutdown of nonurgent services due to coronavirus disease 2019 (COVID-19). […] This institutional review board-approved, retrospective study assessed all patients with diagnostic radiology examinations performed at an academic medical center with eight affiliated outpatient facilities before (January 1, 2020, to March 8, 2020) and after (June 7,2020, to July 15, 2020) COVID-19 shutdown. […] Primary outcome was number of diagnostic radiology examinations per day compared pre- and post-COVID-19 shutdown. […] The COVID-19 pandemic has exacerbated known pre-existing inequities in diagnostic radiology utilization. […] Resources should be allocated to address subgroups of patients who may be less likely to receive necessary diagnostic radiology examinations, potentially leading to compromised patient safety and quality of care. | 2021-01-22 |
| 33482433 | This study examined the possible association between the prognostic nutritional index (PNI) and in-hospital mortality rates in cases with a high cardiovascular risk burden and hospitalized with the diagnosis of coronavirus disease 2019 (COVID-19). | 2021-01-22 |
| 33482920 | However, CDC-approved clinical-grade sampling supplies and techniques using a synthetic swab are expensive, potentially expose laboratory workers to viable virus and prohibit analysis of the microbiome due to the presence of antibiotics in viral transport media (VTM). […] To this end, we performed a series of experiments comparing the diagnostic yield using five consumer-grade swabs (including plastic and wood shafts and various head materials including cotton, synthetic, and foam) and one clinical-grade swab for inhibition to RNA. | 2021-01-23 |
| 33483143 | The radiologic pattern of these infections is nonspecific, and chest X-rays alone are insufficient for the diagnosis. | 2021-01-23 |
| 33483166 | Severe disease was associated with lower hemoglobin prior to coronavirus disease 2019 diagnosis and lower lymphocyte count at the time of diagnosis but not age, sex, ethnicity, or preexisting comorbidities. | 2021-01-23 |
| 33483200 | The exclusion of these conditions is essential to establish the diagnosis. […] The current criteria to establish the diagnosis are not specific and have overlapping features with EVALI, making the accurate diagnosis a clinical challenge during continued COVID-19 transmission within the community. […] WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Physician awareness of overlapping and differentiating EVALI and MIS-C features is essential to direct appropriate diagnostic evaluation and medical management of adolescents and young adults presenting with systemic inflammatory response during the unfolding pandemic of COVID-19. | 2021-01-23 |
| 33483259 | This observational study compared the prevalence of COVID-19 symptoms, diagnosis and hospitalization in IBD patients with a control population with non-inflammatory bowel disorders. […] The prevalence of COVID-19 symptoms, diagnosis and hospitalization for COVID-19 was assessed. 1810 patients (64%) responded to the questionnaire (941 IBD patients and 869 controls). […] IBD patients had a lower rate of nasopharyngeal swab-PCR confirmed diagnosis (0.2% vs 1.2%; OR:0.14, 95%CI:0.03-0.67). | 2021-01-23 |
| 33483314 | This retrospective, territory-wide cohort study used an electronic public healthcare database in Hong Kong to identify patients with SARS or COVID-19 by diagnosis codes, virologic results, or both. | 2021-01-23 |
| 33483321 | Palliation is the only treatment and early diagnosis is an important aspect in relation to gaining speedy access to palliative and end-of-life care services. | 2021-01-23 |
| 33483707 | Based on the results, we identified several S protein-derived 12-mer peptides that have high diagnostic performance. […] Furthermore, the diagnostic performance of the S2-78 (aa 1148-1159) IgG was successfully validated by ELISA in an independent sample cohort. […] The peptides identified in this study may be applied independently or in combination with the S1 protein for accurate, affordable, and accessible COVID-19 diagnosis. | 2021-01-23 |
| 33484085 | The diagnosis of patients with Coronavirus disease 2019 (COVID-19) suspicion but negative reverse transcriptase-polymerase chain reaction (RT-PCR) test is challenging. […] We aimed to investigate the diagnostic value of chest computed tomography (CT) in RT-PCR-negative patients with suspected COVID-19. […] The study included patients who were admitted to our hospital with the suspicion of COVID-19 between 1 April 2020 and 30 April 2020 and tested negative after RT-PCR test, and underwent CT for further diagnosis. […] Seventy-seven patients (22.78%) had extrapulmonary incidental findings CONCLUSION: The diagnostic value of CT in RT-PCR-negative patients with suspected COVID-19 is not very high. | 2021-01-23 |
| 33484229 | Over the past decade, major advancements in the development of mobile applications and telehealth monitoring systems have assisted healthcare professionals in the diagnosis and management of chronic disease. | 2021-01-23 |
| 33484428 | Such developed techniques of severity assessment may be extended to other lung diseases beyond the current pandemic. | 2021-01-23 |
| 33484452 | Despite the alarm that this possibility generated among physicians, there is paucity of information about mechanisms, prevalence, prognosis, diagnosis and therapy of myocarditis in the context of COVID-19. […] This brief review has the goal to revise and summarize current knowledge on myocarditis in COVID-19 patients and underline problems especially related to diagnosis and treatment. | 2021-01-23 |
| 33484783 | It can be a diagnostic challenge to identify COVID-19 patients in whom antibiotics can be safely withheld. | 2021-01-23 |
| 33484862 | Their thorough validation is of extreme importance before using them as epidemiological tools to infer seroprevalence in specific populations, and as complementary diagnostic tools to molecular approaches (e.g. […] This study highlights the sensitivity heterogeneity accompanied by an almost general high specificity of most tests and sets the basis for the usefulness of these tests as a complement for diagnosis and population seroprevalence studies. | 2021-01-23 |
| 33485259 | These techniques are used for the first time in a CoVID-19 sleep study. | 2021-01-23 |
| 33485605 | Towards this effort, the present review discusses the vital concepts related to COVID-19, in terms of its origin, transmission, clinical aspects and diagnosis. | 2021-01-24 |
| 33485971 | RDNI has been recommended for treating Coronavirus Disease 2019 (COVID-19) in the “New Coronavirus Pneumonia Diagnosis and Treatment Plan”. | 2021-01-24 |
| 33486013 | Following diagnosis, the challenge was to identify the appropriate treatment modality for this unique situation. | 2021-01-24 |
| 33486074 | Mitigation of the ongoing COVID-19 pandemic requires reliable and accessible laboratory diagnostic services. | 2021-01-24 |
| 33486135 | Early diagnosis of COVID-19 is the most effective method to control disease spread and prevent further mortality. | 2021-01-24 |
| 33486146 | Food and Drug Administration (FDA)-approval and rollout of the Pfizer-BioNTech and Moderna COVID-19 vaccines, it is important for radiologists to consider recent COVID-19 vaccination history as a possible differential diagnosis for patients with unilateral axillary adenopathy. | 2021-01-24 |
| 33486262 | The COVID-19 pandemic is one such challenge that is testing the performance of both our conventional and newly-developed disease diagnostic technologies. | 2021-01-24 |
| 33486333 | Understanding immunology of COVID-19 is important in developing effective therapies as well as diagnostic, and prophylactic strategies for this disease. | 2021-01-24 |
| 33486387 | Diagnostic microbiology services form a critical component of the response to infectious disease outbreaks. […] As with other laboratories, numerous other challenges were also faced during this period, including the requirement to introduce a new and unaccredited diagnostic PCR assay for SARS-CoV-2, local and global shortages of reagents for sampling and sample processing, and a significant institutional SARS-CoV-2 outbreak in our laboratory catchment area. […] A successful service delivery during this period could only be maintained by a dynamic whole-of-laboratory and organizational response including (1) operational changes to the hours of service and the expansion of diagnostic testing at our laboratory site and other sites within our organization (2) careful management of specialist staff and re-training and recruitment of additional staff (3) changes to laboratory workflows to improve SARS-CoV-2 PCR test turnaround time and to accommodate limits to precious laboratory reagents; (4) clear communication within our laboratory and the NSW Health Pathology organization; and (5) collaborative co-ordination and support by NSW Health Pathology. | 2021-01-24 |
| 33486624 | These data show that it may be beneficial to develop dynamic prevention, early diagnosis and treatment strategies for this vulnerable group of patients who are affected by the infection so much. | 2021-01-24 |
| 33486649 | Patients whose diagnosis was confirmed by reverse-transcriptase polymerase chain reaction (RT-PCR) were called by phone, and their chronic ocular disease, previous ocular surgery, ocular medication, contact lens wear and ocular irritation symptoms were queried during the active disease period. | 2021-01-24 |
| 33486885 | With specific regard to the achievement of WHO hepatitis elimination goals, all measures that will be put in place during and after COVID-19 pandemic could be transferred in increasing diagnosis and linkage to care of people with hepatitis. | 2021-01-24 |
| 33486896 | Analyses were conducted on 4413 patients with an ICD-10 diagnosis of type 2 diabetes and COVID-19. | 2021-01-24 |
| 33487012 | Diagnosis of COVID-19 within seven days of admission (likely community acquired) was independently associated with male sex (odds ratio (OR) 2.34, p = 0.040, confidence interval (CI) 1.04 to 5.25) and symptoms of COVID-19 (OR 15.56, CI 6.61 to 36.60, p < 0.001). […] Diagnosis of COVID-19 made between seven and 30 days of admission to hospital (likely hospital acquired) was independently associated with male sex (OR 1.73, CI 1.05 to 2.87, p = 0.032), Nottingham Hip Fracture Score ≥ 7 (OR 1.91, CI 1.09 to 3.34, p = 0.024), pulmonary disease (OR 1.68, CI 1.00 to 2.81, p = 0.049), American Society of Anesthesiologists (ASA) grade ≥ 3 (OR 2.37, CI 1.13 to 4.97, p = 0.022), and length of stay ≥ nine days (OR 1.98, CI 1.18 to 3.31, p = 0.009). | 2021-01-25 |
| 33487038 | After multivariate analysis, PTs’ perceived stress remained associated with female sex, younger age, previous diagnosis of depressive or anxiety disorder, worsening in sleep patterns, large reduction in family income, housework, relationship with the partner, concern about close people/family members being infected by SARS-CoV-2, and loneliness. | 2021-01-25 |
| 33487146 | ROC-analysis was used for evaluating the diagnostic significance of different EchoCG parameters for prediction of a specific outcome and its probability. […] Overall diagnostic significance was 90.0±2.9 %. | 2021-01-25 |
| 33487174 | Radiological imaging methods have an invaluable role in diagnosis, follow-up, and treatment. | 2021-01-25 |
| 33487301 | The nutritional diagnosis and early nutritional management of COVID-19 patients must be integrated into the overall therapeutic strategy. | 2021-01-25 |
| 33487401 | Knowledge of the many etiologies of this pattern can be useful in preventing diagnostic errors. […] In addition, although the etiology of subpleural sparing pattern is frequently indistinguishable during an initial radiologic evaluation, the differences in location of opacities in the lungs, as well as the presence of additional radiologic findings, patient history, and clinical presentation, can often be useful to suggest the appropriate diagnosis. […] This review aims to describe the primary differential diagnosis of subpleural sparing pattern seen on chest imaging with a strong emphasis on clinical and radiographic findings. […] We also discuss the pathogenesis and essential clues that are crucial to narrow the differential diagnosis. | 2021-01-25 |
| 33487473 | Lung ultrasound (LUS) has shown promising diagnostic potential in different pulmonary conditions. […] We evaluated the diagnostic accuracy of LUS for pulmonary COVID-19. […] Association of a summation score (0-36 points) with the final diagnosis was tested using the area under the receiver operating characteristic curve and sensitivity and specificity at different cutoff points. […] LUS score showed excellent diagnostic performance, with an odds ratio of 1.30 per point (95% confidence interval [CI], 1.09-1.54, p = 0.003) and an area under the curve of 0.85 (95% CI, 0.71-0.99). | 2021-01-25 |
| 33487583 | Dentists’ awareness of the diagnostic criteria for case definition of COVID-19 can facilitate early detection of the disease. | 2021-01-25 |
| 33487628 | Cognitive changes associated with COVID-19 will have increasing significance for patient diagnosis, prognosis, and long-term care. | 2021-01-25 |
| 33487783 | This situation has created enormous demand for the improvement of current diagnostic methods and the development of new diagnostic methods for fast, low-cost and user-friendly confirmation of SARS-CoV-2 infection. […] This critical review focuses on viral electrochemical biosensors that are promising for the development of rapid medical COVID-19 diagnostic tools. […] The advantages and drawbacks of conventional diagnostic methods, such as quantitative reverse-transcription polymerase chain reaction (qRT-PCR), are critically discussed. | 2021-01-25 |
| 33488517 | Six of the nine COVID-19 critically ill patients had random plasma cortisol concentrations below 10 µg/dl, which met the criteria for the diagnosis of CIRCI. | 2021-01-25 |
| 33488691 | Chest X-rays are one of the most common but most difficult to interpret radiographic examination for early diagnosis of coronavirus-related infections. […] Consequently, this swift and computer-aided diagnosis can help in saving precious human lives and minimizing the social and economic impact on society. | 2021-01-25 |
| 33488698 | Based on our experience with the 11 COVID-19 patients who had undergone endoscopy, we provide an endoscopic reprocessing method for the bedside endoscopic diagnosis and treatment of COVID-19 patients for reference. | 2021-01-25 |
| 33488791 | A receiver operating characteristic (ROC) curve analysis was used to compare the diagnostic efficacy of different indexes. […] Among all individual indexes, hsCRP had the highest diagnostic efficacy (area under the curve=0.870), with a sensitivity and specificity of 0.828 and 0.802, respectively. | 2021-01-25 |
| 33488837 | To make more accurate diagnosis on COVID-19 than existing approaches, this paper proposed a novel method combining DenseNet and optimization of transfer learning setting (OTLS) strategy. | 2021-01-25 |
| 33488897 | Since the widespread of acute respiratory syndrome infection caused by Coronavirus-19, unenhanced computed tomography (CT) was considered a useful imaging tool commonly used in early diagnosis and monitoring of patients with complicated Covid-19 pneumonia. | 2021-01-25 |
| 33489048 | We aimed to examine the characteristics of the cells detected in the pathological rate and/or appearance and whether these findings are related to the clinical course by evaluating the peripheral blood smear at the time of diagnosis in COVID-19 patients. […] Clinical features, laboratory data, peripheral blood smear of fifty patients diagnosed with COVID-19 by PCR was evaluated at diagnosis. […] Increased Pseudo-Pelger-Huet anomaly/mature lymphocyte rate suggests a severe stage disease, while high initial mature lymphocyte and monocytes with vacuoles rates at the time of diagnosis may be an indicator of shortened duration of hospitalization. | 2021-01-25 |
| 33489234 | Previous reports have described its management and treatment in medical units, but have not discussed confirmatory tests or differential diagnosis. | 2021-01-25 |
| 33489242 | The timing of safe cardiac surgery is yet to be clarified in the setting of COVID-19 diagnosis. | 2021-01-25 |
| 33489409 | An emergency flexible ureteroscopy greatly helped in the establishment of the diagnosis. […] The diagnosis was only confirmed in the postoperative period, retrospectively. […] Diagnosis of rare clinical entities can be sometimes challenging in the everyday routine practice. […] Having atypical clinical course, the surgeon should be prepared and sometimes must take responsible decisions promptly, even if needed intraoperatively, to manage unexpected findings in order to get the right diagnosis without compromising the patient’s safety. | 2021-01-25 |
| 33489530 | To date, the diagnostic criteria for COVID-19 include nasopharyngeal and oropharyngeal swabs. […] In the literature, there are few cases of COVID-19 pneumonia diagnosis made using magnetic resonance imaging (MRI). […] She was asymptomatic at the time of the examination and had passed the triage carried out on all the patients prior to diagnostic tests during the COVID-19 pandemic. […] The nasopharyngeal swab later confirmed the diagnosis of SARS-CoV-2 infection. | 2021-01-25 |
| 33489609 | Information obtained from the medical records included demographic data, date of visit, the reason for the visit, history of a similar episode, number of ED visits during the past year, priority given at the ED, length of hospitalization, diagnosis of COVID-19 at KAUH, known chronic diseases, and whether brain imaging was performed with which kind of imaging. | 2021-01-25 |
| 33489624 | The initial diagnosis was blepharitis, and it was recommended that he continue with the warm compresses, and doxycycline 100 mg to use if the symptoms worsened or did not improve. […] Physicians and health care workers should be aware of the ocular manifestations of SARS-CoV-2 to make a timely diagnosis of infected individuals. | 2021-01-25 |
| 33489725 | To develop a fast-track risk score valid for every COVID-19 patient at diagnosis. […] SODA score could improve preventive measures taken at diagnosis in high-risk patients and also relieve resources by identifying very low-risk patients. | 2021-01-25 |
| 33489729 | Since ultrasound semiotics is already widely known and described in other similar diseases (acute respiratory distress syndrome, interstitial flu virus, and pneumonia), thoracic ultrasound is a useful diagnostic tool in different scenarios in the COVID-19 pandemic: in the first triage of symptomatic patients, both in the prehospital setting or in the emergency department, in the prognostic stratification and monitoring of patients with pneumonia, and in the management of patients in the intensive care unit. | 2021-01-25 |
| 33489730 | Ultrasound has been widely used in the COVID-19 pandemic as an extremely reliable technique and has proved to have a key role in the diagnosis and monitoring of patients with acute respiratory failure. […] The diagnostic accuracy of LUS is higher than chest X-ray and similar to computed tomography, which is considered the gold standard. […] COVID-19 pneumonia has some distinctive ultrasonographic signs but not pathognomonic, and LUS significantly improves the management of COVID-19 patients speeding up the diagnostic path. […] The examination is bedside; reduces the risk of contamination, avoiding mobilization of the patients; cuts down the amount of radioactive exposure; and gives real-time answers to many diagnostic and therapeutic doubts. | 2021-01-25 |
| 33489731 | The “gold” standard radiological method for the diagnosis of the lung findings in COVID-19 patients is known to be the chest high-resolution computed tomography. […] However, in a mass casualty scenario, as in times of COVID-19 epidemics, in which emergency departments, intensive care units, and whole hospitals are massive overcrowded and continue to change their original configuration, a more rapid, flexible, and performant diagnostic approach is required. […] Lung ultrasonography, a rapid, reliable, bedside, nonradiating and repeatable examination, with its sensitivity closed to chest CT and much higher than the chest X-ray for COVID patients, has proved to be in COVID-19 pandemic as crucial diagnostic and monitoring tool of patients with acute respiratory failure. […] It could be performed in the prehospital setting, in the emergency department (as part of the diagnostic approach), up to the normal wards and the intensive care unit. […] The aim of this article is to describe the central role of LUS in the management of COVID-19 critically ill patients with acute respiratory distress syndrome, as valid diagnostic and monitoring point-of-care technique. | 2021-01-25 |
| 33489732 | The pandemic caused by the new SARS-CoV-2, named coronavirus disease 2019 (COVID-19) disease, has challenged the health-care systems and raised new diagnostic pathways and safety issues for cardiac imagers. […] Myocardial injury may complicate COVID-19 infection in more than a quarter of patients and due to the wide a range of possible insults, cardiac imaging plays a crucial diagnostic and prognostic role. […] The health-care system and physicians are called to reorganize the diagnostic pathways to minimize the possibility of spreading the infection. | 2021-01-25 |
| 33489733 | Moreover, CT has demonstrated a prognostic role in patients with a diagnosis of COVID-19 pneumonia. […] Lung ultrasounds (LUS) are an emergent tool in the diagnosis of the disease. […] The adoption of LUS combined to chest X-rays in COVID-19 in pneumonia diagnosis is an interesting prospect that needs to be confirmed. | 2021-01-25 |
| 33490143 | The coronavirus disease 2019 (COVID-19) has already become a pandemic wherein the infection’s timely diagnosis has proven beneficial to patient treatment and disease control. […] Nucleic acid detection has been the primary laboratory diagnostic method for the detection of SARS-CoV-2. | 2021-01-25 |
| 33490198 | Therefore, we seek to provide an overview of SARS-CoV-2, including its classification, origin, genomic structure, replication cycle, transmission, pathogenesis, clinical aspects, diagnosis, treatments, prevention and vaccine options. | 2021-01-25 |
| 33490654 | PRES occurrence may be less rare than supposed in COVID-19 patients and a high suspicion index is warranted for prompt diagnosis and treatment. | 2021-01-25 |
| 33490695 | Following the fast and pandemic-scale spread of COVID-19, mutations in SARS-CoV-2 have raised new diagnostic challenges which include the redesign of the oligonucleotide sequences used in RT-PCR assays to avoid potential primer-sample mismatches, and decrease sensitivities. […] Hence, this article sought to offer detailed biology of SARS-CoV-2 re-infections and their implications on immune response milieu, diagnostic laboratory tests and control measures against COVID-19. | 2021-01-25 |
| 33490856 | This research will propose two topic mining that can handle a large-scale dataset-rolling online non-negative matrix factorization (Rolling-ONMF) and sliding online non-negative matrix factorization (Sliding-ONMF)-and compare the insights produced by both techniques. | 2021-01-25 |
| 33490871 | However, they are the common lower respiratory tract specimens submitted for laboratory diagnosis. | 2021-01-25 |
| 33490967 | Since there is direct association between electrocardiography (ECG) data and the prognosis of cardiovascular disease, a systematic literature review was performed in the present study to address this association and make a conclusive agreement on the early diagnostic and prognostic values of ECG in patients with COVID-19. […] It is recommended to use ECG as a valuable diagnostic and prognostic tool for cardiac evaluation of patients with COVID-19. | 2021-01-25 |
| 33491346 | Patients were admitted to the 118 Emergency Pre-Hospital and Emergency Department based on two diagnostic criteria, the nasopharyngeal swab assessed by reverse-transcriptase-polymerase-chain-reaction (RT-PCR) and CT-scan image characterized by ground glass opacity. | 2021-01-25 |
| 33491422 | In this review, we summarized the latest research highlighting the clinical features, pathogenesis, and diagnosis, with a concentration on hematological parameters that predict severity to help identify patients with severe disease. | 2021-01-25 |
| 33491459 | For the standard untargeted 1D, CPMG, and JRES NMR experiments on the same samples, the reduced signal-to-noise was more constraining and required greater scanning times to achieve similar differential diagnostic performance (15 min per sample per experiment for 3 mm 1D and CPMG, compared to 4 min for the 5 mm tubes). | 2021-01-25 |
| 33491475 | Patients aged 18 with a cancer diagnosis were eligible to participate and asked about their clinical and demographic characteristics, concerns about research participation given the COVID-19 pandemic, anxiety levels measured using the Generalized Anxiety Disorder-7 (GAD-7) scale, amongst other questions. | 2021-01-25 |
| 33491869 | Therefore, the purpose of this study was to analyse the repercussion of perceived threat from COVID-19 on the mental health of actively employed nurses, considering a COVID-19 diagnosis, whether their own or of someone close to them. | 2021-01-25 |
| 33491921 | They were divided into four diagnostic outcomes according to their clinical records: no-infection, bacterial infection, viral infection and co-infection. | 2021-01-25 |
| 33492003 | Improvements in imaging, especially ultrasound, and especially in the application of rapid molecular diagnosis are likely to have significant impact on the management of CAP. […] Improvements in imaging and pathogen diagnosis are welcome, as is the potential for secondary benefits of anti-COVID-19 therapies that may have reach effect on respiratory viruses other than severe acute respiratory syndrome coronavirus 2. | 2021-01-25 |
| 33492297 | We introduce current initiatives promoting regional diagnosis, visibility, and capacity, including the forthcoming launch of the Latin American Brain Health Institute (BrainLat). | 2021-01-25 |
| 33492524 | A variety of diagnostic techniques, including chest X-rays, computer tomography (CT) scans, analysis of viral nucleic acids, proteins, or whole virions, and host antibody detection using serological assays have been developed for the detection of these viruses. | 2021-01-25 |
| 33492608 | We report seven cases of opsoclonus-myoclonus syndrome presumably parainfectious in nature and discuss their phenomenology, their possible pathophysiological relationship to COVID-19, and diagnostic and treatment strategy in each case. […] Finally, we review the relevant data in the literature regarding the opsoclonus-myoclonus syndrome and possible similar cases associated with COVID-19 and its diagnostic importance for clinicians in various fields of medicine encountering COVID-19 patients and its complications. | 2021-01-25 |
| 33492984 | We defined cancer survivors as adults with a self-reported diagnosis of cancer (n = 854, 7.6%). | 2021-01-25 |
| 33493130 | However, with the increasing use of big data growth in biomedical and healthcare communities, the performance of artificial intelligence (Al) techniques of diagnosis is improving, and can help avoid medical practice errors, including under the current circumstance of the COVID-19. […] This study aims to visualize and measure patients’ heterogeneous preferences from various angles of Artificial intelligence (AI) diagnosis versus clinicians in the context of the COVID-19 epidemic in china. […] We also aim to to illustrate the different decision-making factors of the latent class of discrete choice experiment (DCE) and prospects for the application of AI techniques in judgment and management during the pandemic of SARS-CoV-2 and future. […] Attributes from different dimensions that have been hypothesized: diagnostic method; outpatient waiting time, diagnosis time, accuracy, follow-up after diagnosis and diagnostic expense. […] A total of 55.74% of the respondents (428 out of 767) opted for AI diagnosis regardless of the description of the clinicians. […] The attributes with the most substantial effect and highest percentage weights are the accuracy (39.29% in general) and expense of diagnosis (21.69% in general), especially the preferences for diagnosis ‘accuracy’ attribute, which is constant across classes. […] Latent class analysis was prominent and useful in quantifying preferences for attributes of diagnosis choice. […] People’s preference for the ‘accuracy’ and ‘diagnosis expense’ are palpable. […] However, accuracy and diagnosis expenses need to be taken into consideration. | 2021-01-25 |
| 33493365 | Adjusted prevalence ratios (aPR) of high nAb titre (≥1:160) were estimated by blood group using multivariable modified Poisson regression models that adjusted for age, sex, hospitalization status and time since SARS-CoV-2 diagnosis. | 2021-01-25 |
| 33493416 | The results of our analyses do not provide clear evidence of increased risk of COVID-19 diagnosis, hospitalization or severity, due to asthma. | 2021-01-25 |
| 33493433 | By diagnosis, the largest reduction from 2019 to 2020 in treatment courses was for prostate cancer (77·0% in April) and non-melanoma skin cancer (72·4% in April). | 2021-01-25 |
| 33493593 | We reported a significant increase in the total number of procedures for patients with a chronic limb-threatening ischemia (CLTI) diagnosis (+21%, P < 0.001). […] Stringent protective measures for patient and staff or higher use of endovascular techniques and local anesthesia are some of the successful changes implemented in the department. | 2021-01-25 |
| 33493853 | We also generate sensitivity, specificity, positive and negative likelihood ratio (PLR & NLR), diagnostic odds ratio (DOR), and area under curve (AUC). : 32.86%); with sensitivity of 0.74 [0.53, 0.88], specificity of 0.54 [0.29, 0.77], PLR of 1.6 [1.1, 2.3], NLR of 0.49 [0.35, 0.66], DOR of 3 [2, 5], and AUC of 0.70 [0.66, 0.74]. | 2021-01-25 |
| 33493886 | In the medical literature, some case reports on the association of the COVID-19 infection and occurrence of spontaneous subarachnoid hemorrhage (SAH)have been reported Aim of the present paper is to search the causes of this association The diagnosis of COVID-19 was based on the real-time reverse-transcription polymerase chain reaction (PCR) test and computed tomography (CT) of the chest. | 2021-01-25 |
| 33493900 | Amplification-based nucleic acid detection is widely employed in food safety, medical diagnosis and environment monitoring. | 2021-01-25 |
| 33493922 | This analysis summarizes the pathogenicity of COVID-19 and aims to raise awareness of COVID-19 among the population and to continually boost the detection, monitoring, diagnosis and care level. | 2021-01-25 |
| 33494237 | In this review, we present a succinct overview of the SARS-CoV-2 virus structure, molecular mechanisms of infection, COVID-19 epidemiology, diagnosis, and clinical manifestations. | 2021-01-26 |
| 33494406 | As we emanate from the second national lockdown in the UK with mixed feelings of hope and despair-due to vaccination and new COVID-19 variant, respectively-we reflect on the impact of the first wave on the provision on diagnosis and management of with upper gastrointestinal (UGI) cancers. | 2021-01-26 |
| 33494551 | Therefore, the literature review including screening and diagnostic audiometry, cochlear implants and hearing aids, and aural rehabilitation, telecommunications technology regarding several fields of teleaudiology, and considerations for practicing were identified. | 2021-01-26 |
| 33494822 | These findings can aid timely diagnosis of potentially life-threatening COVID-19 myopericarditis with cardiac tamponade. | 2021-01-26 |
| 33494912 | Regional anesthesia techniques were recently introduced to provide analgesia for breast surgery. […] These techniques are rarely used as the primary anesthesia due to the complexity of breast innervation, with numerous structures that can potentially be disrupted during breast surgery. | 2021-01-26 |
| 33495491 | However, there has been substantial variability in the policies and intensity of diagnostic efforts between countries. | 2021-01-26 |
| 33495685 | The early diagnosis of COVID-19 based on detection of reactive oxygen species overproduction because of virus-induced dysfunctioning of lung cells has also been highlighted. | 2021-01-26 |
| 33495740 | PS may also promote thromboinflammation without circulating if expressed on the surface of endothelial cells, a condition that might only be documented if novel imaging techniques are developed. | 2021-01-26 |
| 33495743 | •COVID-19 infection is associated with a prothrombotic state•Point of care ultrasound (POCUS) provides prompt bedside diagnosis of covid-19 complications such as clot in transit•Bedside TEE guidance of mechanical CPR arm placement improves the efficiency of chest compressions. | 2021-01-26 |
| 33495747 | To implement rapid and effective clinical management, early diagnosis is the mainstay. […] Today, real-time reverse transcriptase (RT)-PCR test is the major diagnostic practice as a gold standard method for accurate diagnosis of this disease. […] Herein, we comprehensively review major smart materials such as nanomaterials, photosensitive materials, electrically sensitive materials, their integration with sensor platforms, and applications as wearable tools within the scope of the COVID-19 diagnosis. | 2021-01-26 |
| 33495755 | Results suggested that comparable qualities of diagnosis and surgical treatment as well as perioperative outcomes were safely and successfully achieved. | 2021-01-26 |
| 33495880 | All human, animal, and in vitro studies which used accepted analytic techniques for viral detection were included. | 2021-01-26 |
| 33495916 | This joint position statement of Latin American Medical Societies provides an updated guide for the prevention, diagnosis, and treatment of osteoporotic patients in the face of possible clinical scenarios posed by the COVID-19 health crisis. […] The objective of this study is to provide an updated guide for the prevention, diagnosis, and treatment of osteoporotic patients in the face of possible clinical scenarios posed by the COVID-19 health crisis. | 2021-01-26 |
| 33496362 | LUS-score had only a moderate diagnostic value for requirement of invasive mechanical ventilation in moderate to severe COVID-19. | 2021-01-26 |
| 33496442 | For the apparent validity analysis, 29 people who had been hospitalized in HDS with a COVID-19 infection diagnosis and at the time of the interview were in their homes. | 2021-01-26 |
| 33496647 | At weeks 18-30 after diagnosis, all remained seropositive but spike protein-targeting antibody titers declined. | 2021-01-26 |
| 33496672 | The cancer information needs included general topics such as what cancer is, what causes it, cancer screening and diagnosis, cancer treatment, and practical information on what to expect during cancer care. | 2021-01-26 |
| 33497039 | Some hemodialysis techniques reduce systemic inflammation but their impact on COVID-19 has not been addressed. | 2021-01-26 |
| 33497234 | The study represents the first thorough evaluation of sensitivity and robustness of targeted mass spectrometry in nasal swabs, constituting a promising SARS-CoV-2 antigen assay for the first-line diagnosis of COVID-19 and compatible with the constraints of clinical settings. | 2021-01-26 |
| 33497352 | Analyses using natural language processing techniques with domain expert involvement can produce useful information for public health. | 2021-01-26 |
| 33497372 | SARS-CoV-2 in saliva has been identified in various studies, which suggests that this could be a useful sample for diagnosis. | 2021-01-26 |
| 33497420 | Furthermore, accurate descriptions of seroconversion are needed to inform the best use of serological assays for diagnostic testing and serosurveillance studies. | 2021-01-26 |
| 33497663 | This monumental and rapid undertaking led to the adoption of novel virtual interviewing techniques, many of which have actually been developed and partially rolled out by other specialties for years. […] However, most, if not all, of the novel interview techniques that were rapidly adopted by cardiothoracic training programs during the 2020 interview season will continue to be relevant even after the pandemic and need for social distancing subsides. […] In this literature review, we highlight techniques that can be used by cardiothoracic training programs to virtually showcase their attributes and strengths, in order to give applicants as realistic of a view of the program as possible. | 2021-01-26 |
| 33497877 | The outbreak of life-threatening pandemic like COVID-19 necessitated the development of novel, rapid and cost-effective techniques that facilitate detection of viruses like SARS-CoV-2. […] The presently popular approach of a collection of samples using the nasopharyngeal swab method and subsequent detection of RNA using the real-time polymerase chain reaction suffers from false-positive results and a longer diagnostic time scale. […] Alternatively, various optical techniques namely optical sensing, spectroscopy, and imaging shows a great promise in virus detection. […] The state-of-art research activities in utilizing the photonics tools such as near-infrared spectroscopy, Fourier transform infrared spectroscopy, Raman spectroscopy, fluorescence-based techniques, super-resolution microscopy, surface plasmon resonance-based detection, for virus detection accounted extensively with an emphasis on coronavirus detection. […] The progress in the field of optical techniques for virus detection unambiguously show a great promise in the development of rapid photonics-based devices for COVID-19 detection. | 2021-01-26 |
| 33497879 | Amid the ongoing COVID-19 pandemic, there is an increasing interest in implementing CRISPR-based diagnostic principles to develop fast and precise methods for detecting SARS-CoV-2. […] In this work, we reviewed and summarized these CRISPR-based diagnostic systems as well as their characteristics and challenges. […] We also provided future perspectives of CRISPR-based sensing towards point-of-care molecular diagnosis applications. | 2021-01-26 |
| 33498011 | However, interventions targeting loneliness are less common than interventions for other mental health problems, such as depression and anxiety, and existing interventions focus primarily on building social skills and increasing opportunities for social interaction despite research suggesting these techniques are not the most effective. | 2021-01-26 |
| 33498060 | As the number of patients with this diagnosis is rising, the infection risk for the surgical staff will be higher. | 2021-01-26 |
| 33498106 | Notably, this direct RNA diagnostic technology enables detecting a wide range of RNA molecules at the single-molecule level. | 2021-01-27 |
| 33498157 | Accurate and rapid diagnostic tools are needed for management of the ongoing coronavirus disease 2019 (COVID-19) pandemic. […] We set up LFRET assays for antibodies against SP and NP and evaluated their diagnostic performance using a panel of 77 serum/plasma samples from 44 individuals with COVID-19 and 52 negative controls. | 2021-01-27 |
| 33498180 | Secondary spontaneous pneumothorax (SSP), as a complication in severe forms of COVID-19 pneumonia, especially in female patients without risk factors is rare, and early diagnosis and treatment are essential for increasing the survival chances of these patients. | 2021-01-27 |
| 33498929 | However, early diagnosis and treatment may be associated with positive resolution of these severe complications. | 2021-01-27 |
| 33499223 | The aim of this retrospective study was to investigate the impact of the coronavirus disease 2019 (COVID-19) pandemic on cancer diagnosis in general and specialized practices in Germany. […] Together, these data show that the COVID-19 pandemic had a significant negative impact on cancer diagnosis in Germany, highlighting the need for public health measures improving the management of cancer in this country during this ongoing pandemic. | 2021-01-27 |
| 33499379 | Presently, various techniques are used for the diagnosis of SARS-CoV-2 infection, with various advantages and weaknesses to each. […] In addition, we discuss principles, advantages, and disadvantages of these detection methods, and highlight the potential methods for the development of additional techniques and products for early and fast detection of SARS-CoV-2. | 2021-01-27 |
| 33499580 | This review critically analyzed COVID-19 as a public health hazard in order to help policy makers, health care givers, and primary physicians to promote early diagnosis and prevention. | 2021-01-27 |
| 33500125 | Local as well as global stability of the equilibrium points of the model have been studied using Lyapunov function and the geometrical approach techniques. | 2021-01-27 |
| 33500147 | In the present study, we analyzed the development of antibodies in 77 patients with an oncologic diagnosis 26 days after positive RT-qPCR testing for SARS-CoV2. | 2021-01-27 |
| 33500209 | The diagnosis was made following the ad hoc definitions described for patients admitted to ICU with severe influenza, including clinical criteria (fever for 3 days refractory to the appropriate antibiotic therapy, dyspnea, pleural friction rub, worsening of respiratory status despite antibiotic therapy and need of ventilator support), a radiological criterion (pulmonary infiltrate) and a mycological criterion (several positive galactomannan tests on serum with ratio ≥0.5). […] Galactomannan and Aspergillus DNA detection would be useful methods for Aspergillus infection diagnosis as they allow avoiding the biosafety issues related to these patients. | 2021-01-27 |
| 33500363 | Pooling of up to 5 samples can be employed in laboratories for the diagnosis of COVID-19 for efficient utilization of resources, rapid screening of a greater number of people, and faster reporting of test results. | 2021-01-27 |
| 33500385 | Saliva is increasingly being suggested as an alternate diagnostic sample in SARS-CoV-2 infection. […] This scoping review was done with the objective of exploring the evidence on the role of saliva as an alternate diagnostic sample in SARS-CoV-2 condition. | 2021-01-27 |
| 33500389 | Having combined depression and anxiety symptoms was positively associated with poor adherence to treatment (OR = 1.42, P = 0.02) and more severe insomnia (OR = 1.19, P < 0.01) and pain (OR = 1.15, P < 0.01), and was negatively associated with the diagnosis of schizophrenia (OR = 0.50, P = 0.04) and others (OR = 0.53, P < 0.01). | 2021-01-27 |
| 33500431 | This study describes the diagnosis, symptoms, treatment and outcomes of hospitalized patients with COVID-19 needing oxygen support during their stay on regular ward. […] All 133 patients admitted to the RWTH Aachen university hospital with the diagnosis of COVID-19 were included in an observational registry. | 2021-01-27 |
| 33500453 | For public health interventions, a diagnostic test with high sensitivity and specificity is required. […] The gold standard protocol for diagnosis by the Word Health Organization (WHO) is RT-PCR. […] To detect low viral loads and perform large-scale screening, a low-cost diagnostic test is necessary. […] We validated an auxiliary protocol for molecular diagnosis with the SYBR Green RT-PCR methodology to successfully screen negative cases of SARS-CoV-2. | 2021-01-27 |
| 33500503 | The diagnosis of COVID-19 relies on the direct detection of SARS-CoV-2 RNA in respiratory specimens by RT-PCR. […] The pandemic spread of the disease caused an imbalance between demand and supply of materials and reagents needed for diagnostic purposes including swab sets. […] We assessed the diagnostic performance of an in-house system developed according to recommendations by the US CDC. […] Thus, a simple combination of broadly available materials may enable diagnostic laboratories to bypass global limitations in the supply of swab sets. | 2021-01-27 |
| 33500623 | Currently, the “gold standard” is real-time reverse transcriptase-polymerase chain reaction (RT-PCR) amplification of the viral DNA for diagnosis of COVID-19 infection. […] Early discussions suggested that CT should be the preferred modality for the diagnosis of COVID-19. […] Real-time reverse transcriptase-polymerase chain reaction amplification of the viral DNA for diagnosis of COVID-19 infection. | 2021-01-27 |
| 33500681 | This is not only the case for COVID-19, but for the other abnormalities needing radiological diagnosis as well. […] In this work, we present an automated technique for rapid diagnosis of COVID-19 on computed tomography images. […] In the final phase, the best features are subjected to various classifiers for the diagnosis. | 2021-01-27 |
| 33500689 | Advanced strategies include no-touch techniques such as engineered antimicrobial surfaces and automated room disinfection systems using hydrogen peroxide vapor or ultraviolet light. | 2021-01-27 |
| 33500811 | A 49-year-old male was admitted to the hospital with a diagnosis of cervical stenosis and a C6-C7 disc herniation with spinal cord compression. | 2021-01-27 |
| 33501370 | We compared data from electrocardiograms (ECGs) transmissions and STEMI diagnosis collected between February and April 2020 with the data from the same period of 2019. […] The total number of STEMI diagnosis in the months under examination during 2019 were 47 out of 7463 ECGs (0.63%), while in 2020 were 48 out of 5797 ECGs (0.83%). […] The efficiency of our telecardiology system along with the low spread of the infection in our region contributed to maintaining the number of STEMI diagnosis and patient’s care in line with the past even during the pandemic. | 2021-01-27 |
| 33501506 | F-FDG brain PET of long COVID patients from the same center with a biologically confirmed diagnosis of SARS-CoV-2 infection and persistent functional complaints at least 3 weeks after the initial infection. | 2021-01-27 |
| 33501645 | We aimed to assess the diagnostic value of saliva samples in mildly symptomatic and asymptomatic patients with confirmed Covid-19. […] We performed a cohort study to validate the use of saliva for SARS-CoV-2 detection in mildly symptomatic and asymptomatic patients with a confirmed diagnosis of Covid-19. | 2021-01-27 |
| 33501676 | The difference between clinical size at diagnosis and final pathology size was assessed in 315 stage I-III primary invasive breast cancer patients who were divided into three groups based on the time between diagnosis and definitive surgery. […] Compared with the group with ≤60 days between diagnosis and surgery, tumor growth was observed for 12% of tumors in the 61- to 120-day group and 17% of tumors in the >120-day group (p for trend = 0.032). […] Luminal B phenotype was the only clinical variable known at the time of diagnosis that strongly predicted growth. | 2021-01-27 |
| 33501822 | All interventional pulmonology procedures done during the three months after implementation of lockdown were evaluated retrospectively for patient demographics, clinical diagnosis, indication for procedure and diagnostic accuracy. […] Twenty-three of the procedures were for the diagnostic indication (79%), and six were therapeutic (20.6%). […] The diagnostic yield in suspected neoplasm was 100% while for suspected infections was 58.3%. | 2021-01-27 |
| 33501831 | Swab sample collection and recovery are vital for reducing false negative diagnostic tests, early detection of pathogens, and harvesting DNA from limited biological samples. […] The nanofiber swabs show great promise in improving test sensitivity, potentially leading to timely and accurate diagnosis of many diseases. | 2021-01-27 |
| 33501911 | The authors have reviewed techniques to reduce coughing, thereby decreasing the potential of virus exposure through contact with large respiratory droplets and aerosolized particles that may remain suspended in air. | 2021-01-27 |
| 33501951 | Individual and serial samples covered the time of initial diagnosis, during the disease course, and following recovery. | 2021-01-27 |
| 33502002 | For assessing the risk of bias and quality of included studies, we used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool for observational studies concerned with screening, ROBINS-I for observational ecological studies and a bespoke tool for modelling studies. | 2021-01-27 |
| 33502003 | Two review authors independently rated the quality of included studies using the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool for diagnostic accuracy studies and a modified form designed originally for economic evaluations for modelling studies. […] We rated the certainty of evidence for days to outbreak, transmission, cases missed and detected, diagnostic accuracy (i.e. true positives, false positives, true negatives, false negatives) using the GRADE approach. | 2021-01-27 |
| 33502074 | Immunocompromised patients, including solid organ transplant recipients, may present with atypical symptoms, making the diagnosis of COVID-19 more difficult to make. | 2021-01-27 |
| 33502175 | Early diagnosis of viral infection undoubtedly allows rapid intervention, disease management, and substantial control of the rapid spread of the disease. […] Currently, the standard approach for COVID-19 diagnosis globally is the RT-qPCR test; however, the limited access to kits and associated reagents, the need for specialized lab equipment, and the need for highly skilled personnel has led to a detection slowdown. […] Recently, the development of clustered regularly interspaced short palindromic repeats (CRISPR)-based diagnostic systems has reshaped molecular diagnosis. […] The benefits of the CRISPR system such as speed, precision, specificity, strength, efficiency, and versatility have inspired researchers to develop CRISPR-based diagnostic and therapeutic methods. […] With the global COVID-19 outbreak, different groups have begun to design and develop diagnostic and therapeutic programs based on the efficient CRISPR system. […] CRISPR-based COVID-19 diagnostic systems have advantages such as a high detection speed (i.e., 30 min from raw sample to reach a result), high sensitivity and precision, portability, and no need for specialized laboratory equipment. | 2021-01-27 |
| 33502436 | To assess whether a diagnosis of a schizophrenia spectrum disorder, mood disorder, or anxiety disorder is associated with mortality in patients with COVID-19. […] After adjusting for demographic and medical risk factors, a premorbid diagnosis of a schizophrenia spectrum disorder was significantly associated with mortality (odds ratio [OR], 2.67; 95% CI, 1.48-4.80). […] In comparison with other risk factors, a diagnosis of schizophrenia ranked behind only age in strength of an association with mortality. […] In this cohort study of adults with SARS-CoV-2-positive test results in a large New York medical system, adults with a schizophrenia spectrum disorder diagnosis were associated with an increased risk for mortality, but those with mood and anxiety disorders were not associated with a risk of mortality. | 2021-01-27 |
| 33502483 | Identification of biomarkers associated with ARDS risk may guide clinical diagnosis and prognosis. | 2021-01-27 |
| 33502487 | This prospective cohort study at an academic hospital in Northern Italy was conducted among a consecutive series of patients aged 18 years and older (or their caregivers) who had received a confirmed diagnosis of severe acute respiratory coronavirus 2 (SARS-CoV-2) infection severe enough to require hospital admission from March 1 to June 29, 2020. | 2021-01-27 |
| 33502554 | In patient group, there were no differences in scale scores according to variables such as rheumatological disease diagnosis, the consulting of doctor for treatment, thinking that RD increases the risk of COVID-19, the history of rheumatic disease attack during the pandemic process, and the use of biological agents. | 2021-01-27 |
| 33502593 | Comprehending the pathogenesis of these diseases and exploring novel theories may favor the development of new strategies for diagnosis and therapy in the future. | 2021-01-27 |
| 33502666 | Furthermore, 217/383 reported a previous diagnosis of primary headache disorder: 137 were affected by migraine and 80 had tension-type headache. | 2021-01-27 |
| 33502999 | During our transcript analyses, we identified terms that were related to 24 symptoms outside of those included in the diagnostic criteria for anxiety and depression. | 2021-01-27 |
| 33503002 | The aim of this paper is to describe quantitatively how the abrupt transition to DP might affect the quality of diagnosis, to model the possible causes via probabilistic modeling and to gauge qualitatively the perception of this abrupt transition. […] For each case, several different diagnostic tasks were recorded and answers were compared to the original diagnosis. […] Our diagnostic performance is in line with literature, emphasizing that the duration of transition (lengthy or abrupt) might not influence it. | 2021-01-27 |
| 33504028 | CT images were reviewed first by two radiologists who identified COVID-19 typical CT patterns and then reanalyzed by another two radiologists using a CT structured report for COVID-19 diagnosis. […] The second reading changed the CT diagnosis in 16/60 (26.7%) cases contributing to an increase the concordance with the RT-PCR. […] Double reading of CT scans and expert second readers could increase the diagnostic confidence of radiological interpretation in COVID-19 patients. | 2021-01-28 |
| 33504067 | The present study provides insights on the performance of three fully automated assays, which could help diagnostic laboratories in the choice of a particular assay according to the intended use. | 2021-01-28 |
| 33504309 | Rheumatoid arthritis was the most frequent diagnosis (55%). | 2021-01-28 |
| 33504319 | The patents addressed the issues of diagnosis, therapeutic agents, prevention and control, along with other applications. […] Several promising strategies have been documented in intellectual property databases favoring the need for further studies on the pathogenesis and optimization of the diagnosis and therapeutic treatment for these emerging infections. | 2021-01-28 |
| 33504347 | The day of diagnosis of COVID-19 varied from Day 1 to Day 13, with 63.6% (n = 56) of these in the first week of quarantine. 50% of the people in the SHA were referred to rpavirtual for ongoing clinical management. | 2021-01-28 |
| 33504366 | Among the previous nine BLS and ALS TOR rules, KoCARC TOR rule I was most suitable for predicting poor survival outcomes and showed improved diagnostic performance. | 2021-01-28 |
| 33504377 | This report also highlights the additional benefits of cardiac CT in the diagnosis and follow-up of coronary aneurysms. | 2021-01-28 |
| 33504483 | Age, sex, smoking status, comorbidities, rheumatic disease diagnosis, disease activity and medications were included as covariates in multivariable logistic regression models. | 2021-01-28 |
| 33504593 | Nasopharyngeal (NP) swabs are considered the highest-yield sample for diagnostic testing for respiratory viruses, including SARS-CoV-2. […] We systematically searched PubMed, Google Scholar, medRxiv, and bioRxiv (last retrieval October 1st, 2020) for comparative studies of alternative specimen types [saliva, oropharyngeal (OP), and nasal (NS) swabs] versus NP swabs for SARS-CoV-2 diagnosis using nucleic acid amplification testing (NAAT). […] NP swabs remain the gold standard for diagnosis of SARS-CoV-2, although alternative specimens are promising. | 2021-01-28 |
| 33505425 | Statistical analysis of integral mutations and global spread are necessary and could help improve primer design for nucleic acid diagnosis and vaccine development. […] Mutation analysis of the SARS-CoV-2 can inform primer design for nucleic acid diagnosis to improve virus detection efficiency. | 2021-01-28 |
| 33505640 | To determine the best diagnostic and therapeutic approach, multidisciplinary tumor boards should convene regularly, including through conference calls and telematics platforms. […] A prompt diagnostic workup may reduce children’s suffering and prevent loss of confidence in the health care system among parents. […] Moreover, ensuring adequate support and information regarding measures for preventing SARS-CoV-2 infection in pediatric patients and their families is essential for avoiding panic and excessive stress, allowing early reporting of any suspected symptoms of cancer and, in turn, facilitating early diagnosis and prompt modulation of treatment. | 2021-01-28 |
| 33505649 | Using a prospectively maintained prehospital quality improvement database, we reviewed our hospital EMS transports with a diagnosis of stroke from January to April 2019 (baseline) and January to April 2020 (pandemic). […] We compared the volume of patients, transport/presentation times, severity of presenting symptoms, and final diagnosis. . | 2021-01-28 |
| 33505658 | This case highlights that LTS should be included in the differential diagnosis for patients re-presenting with breathing difficulties after prolonged intubation or tracheostomy for COVID-19. | 2021-01-28 |
| 33505676 | Further studies are needed to address the clinical characteristics, diagnosis and management in COVID-19 patients with active tuberculosis. | 2021-01-28 |
| 33505730 | Consecutive cases of intubated patients in the intensive care unit with the diagnosis of COVID-19 pneumonia and pneumothorax were included. | 2021-01-28 |
| 33505734 | Granulomatosis with polyangiitis (GPA) is a type of small and medium vessel vasculitis that is often associated with pulmonary issues and has been shown to raise diagnostic complications in COVID-19 infection. | 2021-01-28 |
| 33505752 | He was treated according to the diagnosis of Kawasaki disease (KD). […] On the sixth day of hospitalization, the patient experienced hypotension, which necessitated treatment with inotropic drugs and resulted in a change of diagnosis to MIS-C. | 2021-01-28 |
| 33505949 | Clinical characteristics are essential for the correct diagnosis of diseases. […] The current review aimed to summarize the global clinical characteristics of the COVID-19 patients systematically and identify their diagnostic challenges to help the medical practitioners properly diagnose and for better management of COVID-19 patients. […] Global features on the clinical characteristics of COVID-19 obtained from laboratory tests and CT scan results will provide useful information to the physicians to diagnose the disease and for better management of the patients as well as to address the diagnostic challenges to control the infection. | 2021-01-28 |
| 33505977 | In this study, we attempted to identify new transcriptomic signatures as candidate diagnostic models for clinical testing or as therapeutic targets for vaccine design. | 2021-01-28 |
| 33506230 | We examined person-generated health data (PGHD), consisting of survey and commercial wearable data from individuals’ everyday lives, for 230 people who reported a COVID-19 diagnosis between March 30, 2020, and April 27, 2020 (n = 41 with wearable data). | 2021-01-28 |
| 33506402 | Adult patients admitted to the hospital with a COVID-19 diagnosis confirmed by polymerase chain reaction. | 2021-01-28 |
| 33506607 | This progress report discusses the selection of antiviral siRNA sequences, delivery techniques to the infection sites, and provides an overview of antiviral siRNAs against respiratory viruses. | 2021-01-28 |
| 33506942 | To evaluate the diagnostic accuracy of the Food and Drug Administration Emergency Use Authorization (FDA-EUA) authorized point-of-care tests (POCTs) for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] We included studies providing information regarding diagnostic test accuracy of FDA-EUA POCTs for SARS-CoV-2 detection. […] The methodologic quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. […] FDA-EUA POCTs, especially molecular assays, have high sensitivity, specificity, and overall diagnostic accuracy for detecting SARS-CoV-2. | 2021-01-28 |
| 33506943 | It seems that the conduction of routine blood coagulation test could be a beneficial supplementary approach for early diagnosis of COVID-19. | 2021-01-28 |
| 33506970 | All efforts should be made to continue to monitor SARS-CoV-2 genomes for potential variants that can impair diagnostic testing and lead to false negative results. | 2021-01-28 |
| 33506974 | Previous studies have revealed a diagnostic role of pathogen-specific IgA in respiratory infections. […] Our study indicates that co-detection of IgA antibodies for respiratory pathogens might provide diagnostic value for the clinics and also be informative for risk stratification and disease management in COVID-19 patients. | 2021-01-28 |
| 33506983 | As measured by the ATP test, performing diagnostic EGD does not lead to contamination on the face shield of the endoscopist. | 2021-01-28 |
| 33507054 | Patients should be scheduled for an in-person visit when the diagnosis or management plan is in question. | 2021-01-28 |
| 33507259 | This retrospective, observational cohort study included consecutive adult patients hospitalized with a diagnosis of laboratory-confirmed COVID-19 across 36 North American centers from April 15 to June 5, 2020. | 2021-01-28 |
| 33507323 | During the observation period, 1521 persons had hospitalization with COVID-19 as primary or secondary diagnosis. | 2021-01-28 |
| 33507637 | To describe our experience in the diagnostic and therapeutic management of patients with acute abdomen as the main manifestation of SARS-CoV-2 infection. […] For an accurate diagnosis to be achieved, a good clinical record and a comprehensive physical exploration, as well as complementary tests in search of characteristic findings of COVID-19, should be carried out. | 2021-01-28 |
| 33507641 | 5.1% of patients had a positive SARS-CoV-2 diagnostic test. 30 different procedures were carried out, with appendectomy being the most frequent one (n = 13, 19.6% of patients). | 2021-01-28 |
| 33507895 | Among these 446 contacts, five had received a diagnosis of COVID-19 during June-November and were excluded from attack rate calculations. | 2021-01-28 |
| 33507958 | Provide some initial diagnostic criteria using laboratory markers to stratify these patients. […] As diagnostic criteria to define the patients at risk of developing a COVID-19 hyper-inflammatory response, we propose the following parameters (IL-6 > = 40 pg/ml, and/or two of the following: C-reactive protein > = 100 mg/L, D-dimer > = 1000 ng/ml, ferritin > = 500 ng/ml and lactate dehydrogenase > = 300 U/L). | 2021-01-28 |
| 33508260 | The IgG-IgM serological assay has demonstrated good accuracy in early detection in symptomatic patients, but its role in the diagnosis of asymptomatic patients is uncertain. […] However, serological screening showed very low sensitivity with respect to NST in identifying infected workers, and negative IgG and IgM results should not exclude the diagnosis of COVID-19. […] IgG-IgM chemiluminescence immunoassays could increase the diagnosis of COVID-19 only in association with NST, and this association is considered helpful for decision-making regarding returning to work. | 2021-01-28 |
| 33508291 | The most important diagnostic feature in individuals with COVID-19 is lymphocyte depletion, most importantly, T-cells. | 2021-01-28 |
| 33508293 | Due to the importance of detection of diseases and viruses, several techniques have been introduced for detecting process. […] Here, we report the development of biosensors based on various techniques. | 2021-01-28 |
| 33508323 | The special strong periodicity-2 regions and the intensity of periodicity-2 in the SARS-CoV-2 whole genome may become diagnostic and pharmaceutical targets in monitoring and curing the COVID-19 disease. | 2021-01-28 |
| 33508500 | The estimation of tissue oxygenation is vital in the diagnosis and therapeutic evaluation of a huge assortment of diseases. | 2021-01-28 |
| 33508591 | Demographics (including age and gender), diagnosis, plan of treatment, and status of the visit (either new or follow-up) were collected. […] The most common diagnosis among the follow-up cases was chronic rhinosinusitis with nasal polyposis (n = 130, 38.3%). | 2021-01-28 |
| 33508669 | This study supports wastewater-based COVID-19 surveillance of populations in augmenting the efficacy of diagnostic testing, which can suffer from sampling biases or timely reporting as in the case of hospitalization census. | 2021-01-28 |
| 33509306 | Thrombocytopenia had a sensitivity of 0.26 (0.18-0.36), specificity of 0.89 (0.84-0.92), positive likelihood ratio of 2.3 (1.6-3.2), negative likelihood ratio of 0.83 (0.75-0.93), diagnostic odds ratio of 3 (2, 4) and area under curve of 0.70 (0.66-0.74) for composite poor outcome. | 2021-01-29 |
| 33509374 | Early diagnosis of severe acute respiratory syndrome coronavirus 2 pneumonia is not only crucial for both appropriate patient management but also helps to ensure appropriate postexposure precautions are implemented for the department and hospital staff and those who have been in contact with the patient. | 2021-01-29 |
| 33510104 | The objectives of this paper are to gain a better understanding of the key presenting symptoms of COVID-19 in HCWs in a district specialist hospital, to establish the proportion of symptomatic COVID-19 cases among HCWs and its severity and to determine the time taken from onset of symptoms or perceived exposure to diagnostic testing. | 2021-01-29 |
| 33510181 | The COVID-19 pandemic has resulted in an urgent need for a rapid, point of care diagnostic testing that could be rapidly scaled on a worldwide level. | 2021-01-29 |
| 33510247 | We found 1 in 5 patients with a negative swab and clinical suspicion of COVID-19 received a clinical diagnosis of COVID-19 within clinical documentation, discharge summary or death certificate. | 2021-01-29 |
| 33510530 | The diagnosis of multisystem inflammatory syndrome in children was confirmed on the basis of characteristic clinical features and laboratory parameters fulfilling standard case definition for multisystem inflammatory syndrome in children. | 2021-01-29 |
| 33510584 | The techniques applied here to an authentic HIV-1 envelope at two levels of spatial resolution (29 million particles and 280 million atoms) are broadly applicable to the study of other viruses. […] The authors are actively employing these techniques to develop and characterize an authentic SARS-CoV-2 envelope. | 2021-01-29 |
| 33510786 | This narrative review paper defines an ideal extubation, otherwise known as a “smooth extubation,” reviews perioperative criteria for extubation and risks and adverse events related to extubation, and explores various perioperative techniques that can be used to achieve a smooth extubation while caring for an uncomplicated patient without significant risk factors for extubation failure. | 2021-01-29 |
| 33510852 | The role of chest computed tomography (CT) in the screening or diagnosis of COVID-19 remains the subject of much debate. […] Several institutes and organizations around the world have released guidelines, recommendations and statements against the use of CT for diagnosing or screening COVID-19 infection and advocating its use only for those cases with a strong clinical suspicion of complication or an alternate diagnosis. […] However, these guidelines and recommendations are in disagreement with majority of the widely available literature, which strongly favour CT as a pivotal tool in the early diagnosis, management and even follow-up of COVID-19 infection. […] This article besides comprehensively reviewing the current status quo on COVID-19 disease in general, also writes upon the current consensus statements/recommendations on the use of diagnostic imaging in COVID-19 as well as highlighting the precautions and various disinfection procedures being employed world-wide at the workplace to prevent the spread of infection. | 2021-01-29 |
| 33510902 | The granular cast, which is known to be a valuable diagnostic tool for confirming the diagnosis of acute tubular necrosis, was detected in both patients at the onset of AKI. | 2021-01-29 |
| 33510992 | Labs and imaging were consistent with the clinical diagnosis of subacute thyroiditis. | 2021-01-29 |
| 33511330 | Accurate detection, timely diagnosis, effective treatment, and future prevention are the vital keys to management of COVID-19, and can help curb the viral spread. […] Traditionally, biomarkers play a pivotal role in the early detection of disease etiology, diagnosis, treatment and prognosis. | 2021-01-29 |
| 33511381 | The sample-to-answer molecular in vitro diagnostic (IVD) test for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) includes nucleic acid extractions from saliva, removal of dsDNA and quantitative reverse transcription polymerase chain reaction (RT-PCR). | 2021-01-29 |
| 33511392 | Primary diagnosis by whole-slide imaging (WSI) is a key component that would aid departments in providing uninterrupted histopathology diagnosis and maintaining revenue streams from disruption. […] We sought to perform rapid validation of the use of WSI in primary diagnosis meeting recommendations of the College of American Pathologists guidelines. […] Cases were classified as concordant or with minor or major disagreement with the original diagnosis. […] We describe a novel double-blinded method for rapid validation of WSI for primary diagnosis. […] Our findings highlight the occurrence of a range of diagnostic reproducibility when deploying digital methods. | 2021-01-29 |
| 33511662 | To add to this compendium of associations with COVID-19, we would like to report a patient who developed Toxic Epidermal Necrolysis (TEN) following a positive diagnosis of COVID-19. | 2021-01-29 |
| 33511797 | Because prompt detection and proper treatment can be critical to COVID-19 patients, echocardiographic examinations are essential diagnostic tools in the diagnosis and determination of treatment options. […] However, because there is an increased risk of infection during echocardiographic examinations, healthcare providers should pay attention to mitigate the risk of infection during the diagnosis and management of COVID-19 patients. | 2021-01-29 |
| 33511802 | POCUS plays an important role in the bedside diagnosis, hemodynamic assessment and management of patients with acute hypoxic respiratory and circulatory failure with COVID-19 pneumonia. | 2021-01-29 |
| 33511905 | These results highlight the potential utility in assessing level of worry about COVID-19, a transdiagnostic construct, among combustible cigarette smokers to better understand cognitive-affective factors that may maintain smoking behavior in the context of the COVID-19 pandemic. | 2021-01-29 |
| 33512126 | In this case of bicausal diagnosis (the presence of a comorbidity), the primary disease contributed to the acute progression of the background disease (secondary infiltrative tuberculosis with the development of specific pleuritis and pneumothorax with the addition of acute bilateral focal confluent bronchopneumonia with a history of undifferentiated immunodeficiency syndrome. […] Emphasis is laid on the possibility and importance of involving the brain structures in the process in COVID-19 for the timely diagnosis of emerging neurological disorders. | 2021-01-29 |
| 33512464 | Despite the shortcomings, serological assays have an important part to play in combating the pandemic by aiding in diagnosis and sero-epidemiological studies. | 2021-01-29 |
| 33512601 | The diagnostic accuracy of the chest CT suggesting COVID-19 was 71% (95% CI: 65-77%). | 2021-01-29 |
| 33512616 | The high values of sensitivity attained in the present study from a relatively early period of time after hospitalization support the use of the evaluated serological assays as supplementary diagnostic tests for the clinical management of COVID-19. | 2021-01-29 |
| 33512617 | To face the COVID-19 pandemic, the need for fast and reliable diagnostic assays for the detection of SARS-CoV-2 is immense. | 2021-01-29 |
| 33512827 | In the management of AMD, the implementation of artificial intelligence and “virtual clinics” have provided assistance in screening, diagnosis, monitoring of the progression and the treatment of AMD. | 2021-01-29 |
| 33512845 | Out of 243 individuals with a confirmed diagnosis of Crohn’s disease, there was a 24% relative increase in active symptoms between the pre-COVID-19 period to the during-COVID-19 period (P < 0.0001) reflecting an absolute change from 45 to 56%, respectively. | 2021-01-29 |
| 33512891 | To determine if boys with acute testicular torsion, a surgical emergency requiring prompt diagnosis and treatment to optimize salvage of the testicle, delayed presentation to a medical facility and experienced an extended duration of symptoms (DoS), and secondarily, a higher rate of orchiectomy, during the coronavirus disease 2019 (COVID-19) pandemic. | 2021-01-29 |
| 33513044 | This has reduced potential infectious exposure for pregnant mothers and minimized contact between physicians without compromising diagnostic accuracy. | 2021-01-29 |
| 33513240 | Delay in diagnosis and referral may have adversely affected the prognosis and outcome. | 2021-01-29 |
| 33513511 | The Center for Disease Control (CDC) 2019-Novel Coronavirus (2019-nCoV) RT-qPCR Diagnostic Panel was used to identify the presence of SARS-CoV-2 in nasopharyngeal swabs. | 2021-01-29 |
| 33513984 | In this research, we look at the Artificial Intelligence (AI)-based ML and DL methods for COVID-19 diagnosis and treatment. | 2021-01-30 |
| 33513988 | Diagnostic testing remains the backbone of the coronavirus disease 2019 (COVID-19) response, supporting containment efforts to mitigate the outbreak. […] The severity of this crisis and increasing capacity issues associated with polymerase chain reaction (PCR)-based testing, accelerated the development of diagnostic solutions to meet demands for mass testing. […] Since March, the Innovation Observatory has applied advanced horizon scanning methodologies and tools to compile a diagnostic landscape, based upon data captured for molecular (MDx) and immunological (IDx) based diagnostics (commercialized/in development), for the diagnosis of SARS-CoV-2. […] Here we present the global evolution of diagnostic innovations devised to meet changing needs, their regulation and trends across geographical regions, providing invaluable insights into the complexity of the COVID-19 phenomena. | 2021-01-30 |
| 33514012 | The recent development of complex imaging softwares, called deep learning techniques, opens new scenarios for the diagnosis and management. | 2021-01-30 |
| 33514153 | During the COVID-19 outbreak, the auscultation of heart and lung sounds has played an important role in the comprehensive diagnosis and real-time monitoring of confirmed cases. | 2021-01-30 |
| 33514391 | The major problem remains the fear for possible diagnostic delays in life-threatening or crippling diseases; our study doesn’t demonstrate an increase in number or significant delay in some serious conditions such as tumors, peritonitis, diabetic ketoacidosis, ileo-colic intussusception and testis/ovary torsion. | 2021-01-30 |
| 33514406 | Diagnostic swab for COVID-19 was performed in 25% of patients, especially in subjects with co-morbidities or multiple access. […] Only two positive patients fulfilled the criteria for diagnostic swab provided by the Italian Health Authorities, because of close contact with suspected or confirmed cases. | 2021-01-30 |
| 33514761 | These are used as controls, and allow measurement and improvement of the accuracy and quality of diagnostic tests. […] Using a pair of chimeric A/B RNA standards, this allowed incorporation of positive and negative controls into diagnostic testing for the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). | 2021-01-30 |
| 33514852 | Recently, chest computed tomography (CT) has shown utility for COVID-19 diagnosis. | 2021-01-30 |
| 33514902 | Emerging infectious diseases should therefore be considered in the differential diagnosis of ocular inflammatory conditions in patients inhabiting or returning from endemic territories, and more general vigilance is advisable in the context of a global pandemic. […] Eye specialists are in a position to facilitate swift diagnosis, improve clinical outcomes, and contribute to wider public health efforts during outbreaks. | 2021-01-30 |
| 33515095 | Recent publications on the probable role of heparin-binding protein (HBP) as a biomarker in sepsis prompted us to investigate its diagnostic and prognostic performance in severe COVID-19. | 2021-01-30 |
| 33515380 | We collected data retrospectively from the electronic medical records of all patients receiving a diagnosis of COVID-19 between 11th March and 10th May 2020 undergoing maintenance haemodialysis at four satellite dialysis units from the Royal Free London NHS Foundation Trust, London, UK. | 2021-01-30 |
| 33515625 | Significant differences were found between reasons for using telemedicine and diagnosis, occupational status, contact week and treatment. | 2021-01-30 |
| 33515633 | Pool testing is one of the strategy to expedite testing capacities while simultaneously conserving various diagnostic kits, reagents and consumables and time. […] In the present study, we investigated potential role of combined specimen collection technique for the diagnosis of SARS-CoV-2 virus infection where five nasopharyngeal swabs were collected from different individuals and pooled together in a single viral transport medium (VTM). | 2021-01-30 |
| 33515783 | Continuous identification of potential antiviral drugs and diagnostic methods would also be needed. | 2021-01-30 |
| 33515985 | Hence, accurate and cheap portable sensors are crucially important for the clinical diagnosis of COVID-19. […] The presented strategy unlocks a new route for the development of rapid COVID-19 diagnostic tools. | 2021-01-30 |
| 33516166 | Despite the proven diagnosis of haemophagocytic lymphohistiocytosis, the excessively high ferritin levels of the patient did not seem fully explained by this diagnosis. | 2021-01-30 |
| 33517214 | Its diagnosis is late due to the absence of specific clinical and radiological features. | 2021-01-31 |
| 33517343 | It is important to raise awareness of arterial thrombosis as a possible complication of the hypercoagulable state caused by SARS-CoV-2 because prompt recognition is essential for early diagnosis and treatment. | 2021-01-31 |
| 33517462 | Thirty physical therapists working at 11 national public hospitals during the COVID-19 outbreak were recruited by purposeful sampling and snowball techniques. | 2021-01-31 |
| 33517546 | Ultrasound, chest X-ray, and computed tomography (CT) have been used with excellent results in diagnosis, first assessment, and follow-up of COVID-19 confirmed and suspected patients. […] Ultrasound and chest X-ray have the advantages of the wide availability and acquisition at the patient’s bed; CT showed high sensitivity in COVID-19 diagnosis. […] Radiologists should be aware of the advantages and limitations of the available imaging techniques and of the different pulmonary aspects of COVID-19 infection. | 2021-01-31 |
| 33517809 | We illustrate how the primary medical teams and psychiatrists collaborated in clinical diagnosis, treatment, and management. […] Patients with serious mental illness and COVID-19 infection require active collaboration between primary medical teams and psychiatrists for diagnostic clarification, reduction of psychotropic polypharmacy to avoid adverse effects and drug-drug interactions, prevention of psychiatric decompensation, and active management of agitation while balancing staff and patient safety concerns. | 2021-02-01 |
| 33518410 | Molecular detection of SARS-CoV-2 is the only diagnostic test currently available in acutely or recently infected individuals. | 2021-02-01 |
| 33518528 | Urban tertiary care center in New York City. 302 patients admitted in an inpatient setting, ≥18 years old, with a laboratory-confirmed diagnosis of COVID-19 via nasal PCR swab were randomly selected. | 2021-02-01 |
| 33518801 | The current studies have shed a light on molecular docking and molecular dynamics methodologies as powerful techniques in establishing therapeutic strategies to combat COVID-19 pandemic. | 2021-02-01 |
| 33518812 | Although several studies have demonstrated the potential of deep learning in the automatic diagnosis of COVID-19 using CT and X-ray, the generalization on unseen samples needs to be improved. | 2021-02-01 |
| 33518813 | As such, there is a critical need for a quick and automatic diagnostic system. […] Diagnosis from chest CT images is a promising direction. […] To this end, we propose a new deep learning algorithm for the automated diagnosis of COVID-19, which only requires a few samples for training. […] Our results demonstrate the superior performance of our model for the accurate diagnosis of COVID-19 based on chest CT images. | 2021-02-01 |
| 33518818 | Both the short and long-term response strategies adopted by the two supply chains are assessed, using a combination of qualitative and quantitative techniques in three distinct phases. | 2021-02-01 |
| 33518851 | Apart from the gold standard clinical diagnostics, electrochemical techniques have also demonstrated their great potentials in the detection of different viruses and their correlated antibodies and antigens, showing high sensitivities and selectivities, and faster times for the analysis. | 2021-02-01 |
| 33518877 | These outbreaks highlight the pathogenic potential of CoVs and the importance of infection prevention and diagnostic testing to reduce the spread of infectious diseases representing a global health threat. | 2021-02-01 |
| 33518878 | There is a need for effective and reliable systems that perform automatic detection and mass screening of COVID-19 as a quick alternative diagnostic option to control its spread. | 2021-02-01 |
| 33519010 | Accurate and selective assessment of MERS-CoV, SARS-CoV and SARS-CoV-2 would assist in the effective diagnosis of infected individual, offer clinical guidance and aid in assessing clinical outcomes. […] In this mini-review, we review the literature on various aspects, including the history and diversity of SARS-CoV-2, SARS-CoV and MERS-CoV, their detection methods in effective clinical diagnosis, clinical assessment of COVID-19, safety guidelines recommended by World Health Organization and legal regulations. […] This review article also deals with existing challenges and difficulties in the clinical diagnosis of SARS-CoV-2. […] Developing alternative diagnostic platforms by spotting the shortcomings of the existing point-of-care diagnostic devices would be useful in preventing future outbreaks. | 2021-02-01 |
| 33519082 | Non-aerosol techniques and minimally invasive procedures will be preferable whenever possible. […] The moment is suitable for the use of preventive practice and minimally invasive techniques. | 2021-02-01 |
| 33519091 | Those results suggested the POCT system possess the potential to contribute to rapid and accurate serological diagnosis and epidemiological survey of COVID-19. | 2021-02-01 |
| 33519100 | The newly discovered coronavirus (COVID-19) pneumonia is providing major challenges to research in terms of diagnosis and disease quantification. […] Deep-learning (DL) techniques allow extremely precise image segmentation; yet, they necessitate huge volumes of manually labeled data to be trained in a supervised manner. […] It also provides a general framework for lung disease diagnosis in limited data situations. | 2021-02-01 |
| 33519119 | Using a cost-effectiveness analysis method, our results show that combining awareness with diagnosis is the most effective strategy. | 2021-02-01 |
| 33519136 | Data includes; diagnosis, COVID-19 swab dates, results and mortality using orthopaedic admission sheets, patient and pathology electronic recording system. 3/4 of admitted patients tested negative for SARS-CoV-2 initially. | 2021-02-01 |
| 33519188 | We have reviewed the current information on SARS-CoV-2 in the ophthalmologic field and provide up-to-date recommendations to help create protocols that can adapt to the dynamic situation of ophthalmologic institutions, patient cases, economic situations and access to diagnostic tests. | 2021-02-01 |
| 33519247 | We believe that this patient’s diverticulum is very classic, and the treatment plan is highly integrated with the needs of epidemic prevention and control and achieves a satisfactory therapeutic effect, so we hope to provide colleagues with new diagnosis and treatment enlightenment through this case. | 2021-02-01 |
| 33519256 | The presence of viral RNA was evaluated using novel coronavirus nucleic acid diagnostic real time PCR kits. | 2021-02-01 |
| 33519278 | As the number of COVID-19 patients increases dramatically worldwide, there is an urgent need to find a quick and sensitive diagnostic tool for controlling the outbreak of SARS-CoV-2 in the community. […] Today, molecular testing methods utilizing viral genetic material (e.g., PCR) represent the crucial diagnostic tool for the SARS-CoV-2 virus despite its low sensitivity in the early stage of viral infection. | 2021-02-01 |
| 33519319 | The widely used diagnostic test for the SARS-CoV 2 is the real-time reverse transcription-polymerase chain reaction assay while antibody-based techniques are being introduced as supplemental tools, but the lack of specialized nucleic acid extraction and amplification laboratories hampers/slows down timely large-scale testing. | 2021-02-01 |
| 33519321 | To improve diagnosis, we aimed to design and develop a novel advanced AI system for COVID-19 classification based on chest CT (CCT) images. | 2021-02-01 |
| 33519327 | To the best of the authors’ knowledge, there is no similar study that proposes an automated method for COVID-19 diagnosis using EfficientNet. | 2021-02-01 |
| 33519443 | The primary outcome was the clinical diagnosis of COVID-19 performed by a physician at the hospital or at the primary care center, from the March 1-29, 2020. | 2021-02-01 |
| 33519638 | The collected data were analyzed through appropriate statistical techniques. | 2021-02-01 |
| 33519709 | Interestingly, we found that metformin treatment prior to diagnosis of COVID-19 was independently associated with a significant reduction in mortality in subjects with diabetes and COVID-19 (OR 0.33; 95% CI 0.13-0.84; p=0.0210). […] Thus, these results suggest that while diabetes is an independent risk factor for COVID-19-related mortality, this risk is dramatically reduced in subjects taking metformin prior to diagnosis of COVID-19, raising the possibility that metformin may provide a protective approach in this high risk population. | 2021-02-01 |
| 33519745 | The unavoidable shortcomings of traditional diagnostic assay, including nucleic acid testing, diverse serological assays characterized by high-throughput and less workload, are playing a more and more crucial role to supplement the nucleic acid test. | 2021-02-01 |
| 33519973 | Furthermore, context-sensitive interpretation of diagnostic tests is essential. […] This article aims to review understanding of clinicopathological correlation in COVID-19, as well as clarifying the role of current diagnostic techniques. | 2021-02-01 |
| 33520007 | To battle this spread, clinical imaging techniques, for example, computed tomography (CT), can be utilized for diagnosis. | 2021-02-01 |
| 33520015 | According to the diagnosis and treatment plan issued in China and the existing clinical data, Shufeng Jiedu (SFJD) Capsule can be effectively used in the treatment of COVID-19 patients. | 2021-02-01 |
| 33520021 | These changes may not be specific to COVID-19, but owing to the severity of the pandemic, the use of RM to capture patient’s condition makes intuitive sense for early diagnosis, intervention, and additional follow-up in this high-risk population. | 2021-02-01 |
| 33520046 | Early diagnosis of abdominal complications in Covid-19 pneumonia can improve patient outcomes. | 2021-02-01 |
| 33520082 | More patients with atopic disease had COPD listed as a diagnosis in their chart (38.8% versus 17.3%, p < 0.001). | 2021-02-01 |
| 33520094 | Outpatient visit counts by type (in-person, phone, and video) were extracted from the electronic medical record using data warehousing techniques. | 2021-02-01 |
| 33520219 | The diagnosis was based on a set of clinical, biological, radiological and electrocardiographic findings. | 2021-02-01 |
| 33520223 | Radiological evaluation of suspected COVID-19 patients is required for early detection of thoracic involvement, particularly in emergency units, while waiting for definitive diagnosis by real-time reverse transcription polymerase chain reaction (RT-PCR). | 2021-02-01 |
| 33520224 | The diagnosis of indolent systemic mastocytosis can be quite a challenge due to its wide spectrum of clinical manifestations. […] The chronic neglected pruritus and elevated tryptase levels along with histological findings were the main clues that have led us to the final diagnosis of indolent systemic mastocytosis. | 2021-02-01 |
| 33520327 | We also summarize the current diagnostic tools and therapeutic strategies for COVID-19. | 2021-02-01 |
| 33520333 | The results suggest that these bacterial groups can serve as diagnostic biomarkers for COVID-19, and that the Ec/E ratio can be used to predict death in critically ill patients. | 2021-02-01 |
| 33520334 | Creative solutions such as application of topical viricidal agents, make-shift mask filters, three-dimensional (3-D) printable adapters for headlights, aerosol containing separation boxes, and a variety of new draping techniques have been developed to limit the risk of COVID-19 transmission. | 2021-02-01 |
| 33520396 | We present a timely collection of tips, techniques, and strategies for the facilitation of remote teaching sessions and modification of curriculum design, assessment, and evaluation. | 2021-02-01 |
| 33520499 | There are several diagnostic dilemmas with regards confirming VTE among patients with COVID-19 as there is a move to reduce the transfer of patients for angiographic studies or even venous Doppler ultrasonography because of the high transmissibility SARS-CoV-2. […] It is, therefore, crucial to understand the timing of VTE occurrence in the setting of COVID-19, identify strategies for early diagnosis of VTE, therapeutic options as well as prognostic implications of VTE in the setting of COVID-19. | 2021-02-01 |
| 33520543 | Workup for anemia led to the diagnosis of sickle cell disease (SCD). | 2021-02-01 |
| 33520604 | The diagnostic performance of swabs taken from the palatoglossal arch in detecting SARS-CoV-2 infection is similar to that of specimens taken from the nasopharyngeal region. | 2021-02-01 |
| 33520644 | Following epidemiological data, these workers underwent diagnostic testing for COVID-19 (1- nasal or throat swab tests; 2- blood test for enzyme-linked immunosorbent assays [ELISA]; 3- commercial rapid serology test). […] Three diagnostic tests were implemented. | 2021-02-01 |
| 33520958 | diagnostic (IVD) market, current testing landscape for COVID-19 and prospects of microfluidics in next generation diagnostics. | 2021-02-01 |
| 33521007 | Consequently, further research is necessary to determine the diagnostic and pathological significance of oral manifestations of COVID-19. | 2021-02-01 |
| 33521028 | A systematic screening for DVT in patients hospitalized in ICU was not associated with a higher diagnosis of VTE or a reduced diagnosis of PE. | 2021-02-01 |
| 33521076 | Here, we summarize current knowledge on the origin of COVID-19 as well as its epidemiological relationship with humans and animals, genomic resemblance, immunopathogenesis, clinical-laboratory signs, diagnosis, control and prevention, and treatment. | 2021-02-01 |
| 33521183 | The collected ECG images data were manually reviewed by medical professors using Telehealth ECG diagnostic system, under the supervision of senior medical professionals with experience in ECG interpretation. […] The collected data contains 12 leads-based ECG images dataset can be used by Data Scientist, IT Professional and Medical Research Institutes to design, compare, fine-tune classical techniques and Deep learning methods in studies focused on COVID-19, Arrhythmia, and other cardiovascular conditions. […] The dataset contains rare categories of patients that may be used for the development of automatic diagnosis tool for healthcare institutes. | 2021-02-01 |
| 33521210 | By reviewing the pathogenesis of SARS-CoV-2 virus, and understanding the correlation among COVID-19, inflammation, intestinal microbiota, and lung microbiota, we provide perspective in prevention and control, as well as diagnosis and treatment of the COVID-19 disease. | 2021-02-01 |
| 33521254 | It is essential that physicians consider endocrinopathies in the differential diagnosis of such cases, given the risk of life-threatening adrenal crises and their possible contribution to persistent symptoms following recovery from COVID-19. | 2021-02-01 |
| 33521293 | The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. | 2021-02-01 |
| 33521303 | At the peak of the outbreak in Wuhan (January and February), there are two types of COVID-19 patients: laboratory confirmation and clinical diagnosis. | 2021-02-01 |
| 33521379 | It is rational to suppose that persons with coronary artery disease are prone to severe viral infection thereby, guideline-directed diagnosis and medical therapy is vital in CVD patients. | 2021-02-01 |
| 33521383 | Herein, we provide a review in terms of transmission, clinical presentation, diagnosis, and treatment options in clinical trials of COVID-19 (coronavirus disease 2019), because readers need to update themselves regularly, and there is still much more to know about it. | 2021-02-01 |
| 33521384 | Identifying variations in SARS-CoV-2 strains from different regions is a key factor for understanding the pathogenic mechanisms, aid in diagnosis, prevention and therapy of this disease. | 2021-02-01 |
| 33521511 | We provide guidance on risk assessment regarding COVID-19 vaccination in patients with allergic diseases and suggest a standardized, resource-oriented diagnostic and therapeutic procedure. | 2021-02-01 |
| 33521582 | Rule-based live registries were designed in EHR system to classify patients who 1) are currently tested positive for COVID-19; 2) were tested positive but has recovered from COVID-19; 3) are suspected of COVID-19 but did not yet meet clinical diagnostic criteria,; 4) had tested negative for COVID-19; and 5) exceeded a risk score for serious complications from COVID-19. | 2021-02-01 |
| 33521590 | The United States has published the most reports included in the WOS in the categories of non-pharmaceutical interventions, treatment, and vaccine-related reports, while China has published the most literature in the categories of clinical features and complications, virology and immunology, epidemiology, and detection and diagnosis. | 2021-02-01 |
| 33521610 | RT-qPCR is the reference test for identification of active SARS-CoV-2 infection, but is associated with diagnostic delay. […] Yet, their diagnostic test performance in real life settings has not been determined. = 63) in Utrecht and Aruba respectively. | 2021-02-01 |
| 33521621 | A number of serologic tests for immunoglobulin G (IgG) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are now commercially available, including multiple lateral flow immunoassays (LFIAs), which have the advantage of being inexpensive and easy to use, without the reliance on laboratory facilities. […] Median times to first and second tests after diagnosis were 17 (interquartile range, 15-20) and 35 (interquartile range, 30-39) days, respectively. | 2021-02-01 |
| 33521625 | This study combined real-world data and geospatial visualization techniques to demonstrate methods to monitor and communicate the uptake and impact of existing and new vaccines. […] For each week and multiple geographic scales, animated spatial and non-spatial visualization techniques were applied to demonstrate changes in seasonal rotavirus epidemic curves and population-based disease rates before, during, and after vaccine introduction in 2006. | 2021-02-01 |
| 33521671 | Disruption of the health-care system caused by the COVID-19 pandemic exposed weak points in clinical pathways for diagnosis and treatment of giant cell arteritis, but has also permitted innovative solutions. | 2021-02-01 |
| 33521691 | A diagnosis of autoimmune LE was made. | 2021-02-01 |
| 33521735 | : The implementation of social confinement measures to reduce the spread of coronavirus disease 2019 (COVID-19) has limited the clinical and laboratory diagnosis of sexually transmitted diseases (STDs) and their transmission. | 2021-02-01 |
| 33521736 | During the COVID-19 pandemic, poor sanitation is leading typhoid cases to a surge and obsolete diagnostic methods are paving the way towards ir-rational pharmacotherapy. […] Facing COVID-19 and XDR at the same time can lead to a catastrophy, unless the government, the stakeholders and healthcare workers take joint action to improve sanitation, educate the public, vaccinate vulnerable groups and establish good diagnostic and management practices. | 2021-02-01 |
| 33521748 | We simplified our saliva-based diagnostic test by (1) not requiring collection tubes with preservatives, (2) replacing nucleic acid extraction with a simple enzymatic and heating step, and (3) testing specimens with a dualplex qRT-PCR assay. | 2021-02-01 |
| 33521755 | We queried Google Trends for recent (October 2019-October 2020) and seasonal (October 2016-October 2020) trends of search terms pertaining to cardiovascular-related behaviors or clinical care including clinical diagnostic and therapeutic-related terms. […] Key terms related to CVD-related care, including diagnostic and therapeutic-related terms such as “Statin”, “Lipid profile”, “Low-density lipoprotein”, and “Hemoglobin A1C” declined to a four-year low in late March 2020 but regained pre-pandemic search query frequency by July 2020. | 2021-02-01 |
| 33521769 | Participants diagnosed with a psychiatric disorder before Jan 31 were included in the group of individuals with pre-pandemic psychiatric disorders, whereas participants without a diagnosis before the outbreak were included in the group of individuals without pre-pandemic psychiatric disorders. […] We observed excess risk, defined as risk that increased with the number of pre-pandemic psychiatric disorders, across all diagnostic categories of pre-pandemic psychiatric disorders. | 2021-02-01 |
| 33521773 | We describe two interventions to screen for SARS-Co-V2 in two squats of exiled persons in France following the diagnosis of symptomatic COVID-19 cases. | 2021-02-01 |
| 33521783 | The occurrence of stroke during the pandemic as a result of the novel coronavirus has a multifactorial character, and emergency physicians should focus on systematic measures for its screening and accurate diagnosis as well as on appropriate interventions based on early decisionmaking that may have a favorable impact on reducing damage and saving lives. | 2021-02-01 |
| 33522466 | A prolonged incubation period, atypical IC symptoms, and originally altered results of laboratory and instrumental diagnosis are characteristic of recipients due to immunosuppression. […] In 2020, the coronavirus infection (COVID-19) rapidly spread worldwide, and timely diagnosis and searching for effective treatments for this disease became a major challenge. […] Hospitalized patients with moderately severe COVID-19 (n=3) were treated with oxygen inhalation through nasal cannula and prone position with a positive effect.Conclusion Remote counseling of patients after CT and consistency of the outpatient treatment with recommendations of managing transplant physicians provided timely diagnosis of IC, early administration of treatment, and the absence of COVID-19 complications. | 2021-02-01 |
| 33522708 | The present review is designed to provide existing information on the various aspects of the disease such as its clinicopathology, transmission, epidemiology, diagnosis, prevention and control measures, and the potential role of wildlife in the further spread of disease. | 2021-02-01 |
| 33522892 | Although alcohol use has increased in response to the pandemic, no known studies have identified transdiagnostic risk factors for greater drinking in response to COVID-related distress. | 2021-02-01 |
| 33522893 | Some COVID-19 patients experience sudden and rapid deterioration with the onset of fatal cytokine storm syndrome (CSS), which have increased interest in CSS’s mechanisms, diagnosis and therapy. […] However, it should be emphasized that HLH/CSS diagnosis is difficult at the early stages due to the non-specific clinical signs and symptoms, which tends to result in missed and incorrect diagnoses. […] Therefore, clinicians should not only possess extensive clinical experience to ensure high sensitivity to the characteristics of HLH/CSS but must also be familiar with HLH-2004/2009 diagnostic criteria, and HScore methods. […] The paper concisely comment evolution of CSS classifications, cytokines associated with CSS, evolution of CSS diagnostic criteria and importance of the correct identification of hemophagocytes in diagnosing CSS, which is timely and may benefit clinicians familiar HLH-2004/2009 diagnostic criteria, and HScore methods. […] In addition, clinicians must also understand that there are some limitations to these diagnostic criteria. | 2021-02-01 |
| 33522907 | A retrospective analysis was performed in all patients ≤50 years with a confirmed diagnosis of COVID-19 admitted to Emergency department (ED) of San Salvatore Hospital in Pesaro from February 28th to April 8th, 2020. | 2021-02-01 |
| 33522933 | The aims of this study were to describe the immediate actions made by chiropractic programs to deliver education for manual therapy techniques and to summarise the experience of academics who teach manual therapy techniques during the initial outbreak of COVID-19 pandemic. […] This study used a qualitative descriptive approach to describe how some chiropractic programs immediately responded to the initial outbreak of the COVID-19 pandemic in their teaching of manual therapy techniques. | 2021-02-01 |
| 33522942 | Its diagnosis is based on immunotherapeutic histories, clinical symptoms, and the computed tomography (CT) imaging. […] Thus, clinicians are cautious in differential diagnosis especially in COVID-19 epidemic areas. […] Therefore, differential diagnosis depends on the epidemiological and immunotherapy histories, RT-PCR tests. […] The response to glucocorticoid is still controversial but helpful for the diagnosis. | 2021-02-01 |
| 33523020 | Significant efforts are being invested in the development and validation of digital outcomes to support diagnosis and track motor and mobility impairments “off-line”. | 2021-02-01 |
| 33523309 | Early diagnosis of the coronavirus disease in 2019 (COVID-19) is essential for controlling this pandemic. […] The deep learning techniques used in the proposed method is based on a convolutional neural network (CNN). […] Our manuscript focuses on differentiating the CT scan images of COVID-19 and non-COVID 19 CT using different deep learning techniques. […] A self-developed model named CTnet-10 was designed for the COVID-19 diagnosis, having an accuracy of 82.1%. […] Automated diagnosis of COVID-19 from the CT scan pictures can be used by the doctors as a quick and efficient method for COVID-19 screening. | 2021-02-01 |
| 33523318 | During the study period, 37,968 patients were hospitalized with a diagnosis of COVID-19. | 2021-02-01 |
| 33523457 | The clinical practice of postoperative analgesia, recommendations, the diagnosis, assessment and pharmachologic treatment of acute postoperative pain with the current available agents in Turkey are discussed in this article. | 2021-02-01 |
| 33523608 | Undetectable by current diagnostic methods, capillary flow disturbances limit oxygen diffusion exchange in lungs and tissue and may therefore cause hypoxemia and tissue hypoxia. | 2021-02-01 |
| 33523642 | Such polymers have served as therapeutic tools for drug delivery, including antigens, proteins, and genes, as well as diagnostic devices. | 2021-02-01 |
| 33523770 | Our brief review strongly recommends the application of saliva/tears and exhaled breath as clinical samples using technics such as high-performance liquid chromatography-laser-induced fluorescence, photoacoustic spectroscopy, and e-Nose, respectively, for the fast diagnosis of viral infections. | 2021-02-01 |
| 33524031 | The use of an in app survey and analytics can help identify gaps and opportunities for regional anesthesia techniques and practices. | 2021-02-01 |
| 33524188 | Approximately one third of patients with cirrhosis, especially those with decompensation, die after a median of 10 days from COVID-19 diagnosis, and nearly two-thirds of these deaths occur before intensive care unit admission for COVID-19-related pulmonary insufficiency. | 2021-02-01 |
| 33524238 | Next, we will focus on the different hallmarks of cellular senescence and cellular ageing, and the detection techniques most suitable for immune cells. […] Applying these techniques will deepen our understanding of immune cell senescence and to discover potential druggable pathways, which can be modulated to reverse immune ageing. | 2021-02-01 |
| 33525087 | Sophisticated techniques of sensitivity analysis are employed to determine the impacts of model parameters on basic reproduction number and symptomatic infected individuals. | 2021-02-02 |
| 33525201 | A cut-off of 33 identified a probable diagnosis of post-traumatic stress disorder while a cut-off of 22 identified subclinical post-traumatic stress disorder. 503 residents completed the questionnaire. […] Among residents who were directly involved in the clinical assistance of COVID-19 patients, 34.3% presented a probable diagnosis of post-traumatic stress disorder, while 21.5% presented subclinical post-traumatic stress disorder. | 2021-02-02 |
| 33525207 | A total of 117 patients were admitted with a diagnosis of facture and surgically treated, with no cases of COVID-19 positive patients. | 2021-02-02 |
| 33525216 | We also applied multivariate regression techniques to adjust for several epidemiological factors. | 2021-02-02 |
| 33525226 | The first and most accessible diagnostic information is from symptoms and signs from clinical examination. […] Formal diagnosis requires laboratory analysis of nose and throat samples, or imaging tests like CT scans. […] Considering the broad spectrum of clinical manifestations and the increasing worldwide burden of the disease, there is an urgent need to rapidly scale up the diagnostic capacity to detect COVID-19 and its complications. | 2021-02-02 |
| 33525228 | In this literature review, we describe the diagnosis, management, and implications of pulmonary hypertension (PH) among patients with COVID-19. | 2021-02-02 |
| 33525255 | Laboratory findings were consistent with a diagnosis of moderate diabetic ketoacidosis. | 2021-02-02 |
| 33525651 | Containment strategies rely firstly on rapid and sensitive laboratory diagnosis, with molecular detection of the viral genome in respiratory samples being the gold standard. […] The reliability of diagnostic protocols could be affected by SARS-CoV-2 genetic variability. […] In fact, mutations occurring during SARS-CoV-2 genomic evolution can involve the regions targeted by the diagnostic probes. […] Following a review of the literature and an in silico analysis of the most recently described virus variants (including the UK B 1.1.7 and the South Africa 501Y.V2 variants), we conclude that the described genetic variability should have minimal or no effect on the sensitivity of existing diagnostic protocols for SARS-CoV-2 genome detection. | 2021-02-02 |
| 33525739 | An interest in extracorporeal membrane oxygenation (ECMO), the pinnacle of ECLS techniques, has recently increased, as for the last decade, we have observed improvements in the survival of patients suffering from severe acute respiratory distress syndrome (ARDS) while on ECMO. | 2021-02-02 |
| 33526393 | Baseline characteristics did not differ during both periods however, infection control measures and additional investigation were required to clarify the diagnosis during the pandemic, resulting in a signal towards longer door-to-balloon times (95.9 min vs. | 2021-02-02 |
| 33527042 | Our patient didn’t want to go for any invasive diagnostic procedures and favored to wait for spontaneous recovery. | 2021-02-02 |
| 33527080 | The present pandemic situation due to coronavirus has led to the search for newer prevention, diagnostic, and treatment methods. | 2021-02-02 |
| 33527081 | IgM, IgA, and IgG were detected within the first week of diagnosis, with IgG appearing earlier and at higher titers. […] Neutralizing antibodies developed during the second week, reaching high titers 32 days after diagnosis. […] Profiling antibody response and neutralizing activity can assist in laboratory diagnosis and surveillance actions. | 2021-02-02 |
| 33527095 | Delirium may precede respiratory symptoms, and in some cases, it may be the only symptom, leading to a delay in the diagnosis. | 2021-02-02 |
| 33527126 | Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. | 2021-02-02 |
| 33527198 | We aimed to train and test a deep learning classifier to support the diagnosis of coronavirus disease 2019 (COVID-19) using chest x-ray (CXR) on a cohort of subjects from two hospitals in Lombardy, Italy. […] This preliminary experience based on ten CNNs trained on a limited training dataset shows an interesting potential of deep learning for COVID-19 diagnosis. | 2021-02-02 |
| 33527375 | Current diagnostic standards involve SARS-CoV-2 detection in nasopharyngeal swabs (NPS), but saliva is an attractive and non-invasive option for diagnosis. | 2021-02-02 |
| 33527409 | Real-time PCR is the reference method for the diagnosis of SARS-CoV-2 infection; however, the unprecedented increase in the number of infections worldwide calls for faster and easy methods that do not require skilled personnel and special equipment. | 2021-02-02 |
| 33527510 | To identify the main diagnostic features of SARS-CoV-2-positive patients at the time of hospitalisation and their prevalence. […] A rapid review and meta-analysis were carried out to identify the main diagnostic features of SARS-CoV-2-positive patients at the time of hospitalisation. […] This review provides an up-to-date synthesis of main diagnostic features of SARS-CoV-2-positive patients at the time of hospitalisation. | 2021-02-02 |
| 33527658 | In addition, an illustrative case is provided to emphasize the need to consider the diagnosis of neurosyphilis in HIV patients, and if delineated, to be prepared for a severe JHR. | 2021-02-02 |
| 33527788 | It is difficult to distinguish subtle differences shown in computed tomography (CT) images of coronavirus disease 2019 (COVID-19) and bacterial pneumonia patients, which often leads to an inaccurate diagnosis. […] It is desirable to design and evaluate interpretable feature extraction techniques to describe the patient’s condition. | 2021-02-02 |
| 33527848 | ozone generation are complementary techniques for an effective virucidal treatment of the air. | 2021-02-02 |
| 33528146 | The purpose of this study was to investigate whether a history of cardiovascular disease or cancer affects the risk of dying after a COVID-19 diagnosis in Norway. […] Increasing age, male sex (relative risk (RR): 1.5; confidence interval (CI): 1.2-2.0), prior stroke (RR: 1.5; CI: 1.0-2.1) and cancer with distant metastasis at the time of diagnosis (RR: 3.0; CI: 1.1-8.2) were independent risk factors for death after a diagnosis of COVID-19. […] Male sex, and a previous diagnosis of stroke or cancer with distant metastasis were also associated with an increased risk of death after a COVID-19 diagnosis. | 2021-02-02 |
| 33528801 | The financing system impacts were analyzed according to the Diagnosis Related Groups (DRG), the costs accounting method mostly used in European countries. | 2021-02-02 |
| 33528945 | To further control its transmission, early laboratory diagnosis of both asymptomatic and symptomatic patients is crucial. […] Presently, the COVID-19 diagnosis of infected individuals is dependent on computed tomography scanning and real-time polymerase chain reaction (PCR). […] The latter is considered more sensitive and efficient for early diagnosis. […] In this review, general comparisons are made (cases, fatality rate, incubation period, clinical features, and reservoirs) and diagnostic laboratory procedures (specimens, extraction methods, and positive rates by real-time PCR) are compared between SARS, Middle East Respiratory Syndrome, and SARS-2. […] As the COVID-19 cases are persistently increasing, the selection of appropriate specimens and laboratory assay would help in rapid and timely diagnosis. | 2021-02-02 |
| 33529045 | Two hundred thirty-nine cases (58%) underwent standard-of-care diagnosis, workup, and treatment plan. | 2021-02-02 |
| 33529154 | Many research studies on chest diseases rely on the strengths of deep learning techniques. […] Although some of these studies used state-of-the-art techniques and were able to deliver promising results, these techniques are not very useful if they can detect only one type of disease without detecting the others. […] The main objective of this study was to achieve a fast and more accurate diagnosis of COVID-19. […] This study proposes a diagnostic technique that classifies COVID-19 x-ray images from normal x-ray images and those specific to 14 other chest diseases. | 2021-02-02 |
| 33529155 | We utilized natural language processing (NLP) and machine learning techniques to automate the process of judging the conformity of each tweet with each of the four HBM constructs. 5,000 tweets were manually annotated for training the machine learning architecture. | 2021-02-02 |
| 33529156 | The mean amplitude of this circadian pattern differed between individuals during the 7 days before and the 7 days after a COVID-19 diagnosis compared to this metric during uninfected time periods (P =0.01). […] Longitudinally collected HRV metrics from a commonly worn commercial wearable device (Apple Watch) can identify the diagnosis of COVID-19 and COVID-19 related symptoms. […] Prior to the diagnosis of COVID-19 by nasal PCR, significant changes in HRV were observed demonstrating its predictive ability to identify COVID-19 infection. | 2021-02-02 |
| 33529157 | Factors associated with escalation to hospital care were the following: hypertension (odds ratio [OR] 3.6, 95% CI 1.28-9.87; P=.01), sputum production (OR 5.2, 95% CI 1.74-15.49; P=.001), and arthralgia (OR 3.8, 95% CI 1.21-11.71; P=.02) at illness onset and a polymerase chain reaction cycle threshold of ≤20 on a diagnostic nasopharyngeal swab (OR 5.0, 95% CI 1.25-19.63; P=.02). | 2021-02-02 |
| 33529223 | In the ongoing pandemic situation of COVID-19, serological tests can complement the molecular diagnostic methods, and can be one of the important tools of sero-surveillance and vaccine evaluation. | 2021-02-02 |
| 33529270 | The average diagnostic accuracy of the PMM was always above 90% and reached 100% for some parameters, compared to 80% accuracy for the Generalized Monitoring Models (GMM). | 2021-02-02 |
| 33529514 | The results of the analysis show that a greater number of general symptoms should lead to a diagnosis of influenza or common cold rather than COVID-19. | 2021-02-02 |
| 33529750 | Herein, we review the current understanding, diagnosis and treatment of ME/CFS and summarize past clinical studies aimed at identifying effective therapies. | 2021-02-02 |
| 33529763 | The combined usage of these techniques dramatically increased gp120 expression levels and yielded a functional product with human cell derived glycan. | 2021-02-02 |
| 33529907 | This study aimed to investigate whether differences in NLR among real-time polymerase chain reaction (PCR)-positive and -negative patients presenting with a prediagnosis of COVID-19 pneumonia could be useful in the differential diagnosis. […] Early diagnosis and treatment of these patients are crucial, as COVID-19 pneumonia shows a rapid progression in most cases. […] Thus, leukopenia, thrombocytopenia, elevated NLR, and elevated ferritin may be useful as supplementary diagnostic tests in these patients, which may allow early initiation of treatment and may contribute to preventing progression in patients with abnormal results. | 2021-02-02 |
| 33530015 | The primary independent variable was a 3-category variable: physical health diagnosis alone, mental health diagnosis alone, and combined mental and physical health diagnoses. […] Compared to physical health diagnosis alone, mental health diagnosis alone had lower odds of screening positive (OR=0.68, CI=0.51;0.92) and was not associated with hospitalization or mortality among positive screens. […] Overall, compared to physical health diagnosis alone, mental health diagnosis and combined had lower odds of positive screens. […] These findings add new evidence for risk of COVID-19 and related hospitalization in individuals who have a physical and mental health diagnosis. | 2021-02-02 |
| 33530092 | Patients with a diagnosis of ischemic stroke, TIA, or MI documented anonymously in 1,262 general practices in Germany were included. | 2021-02-02 |
| 33530272 | In all cases, diagnosis was confirmed using an electrocardiogram, assessment of laboratory cardiac markers, and imaging. | 2021-02-03 |
| 33530346 | The benefits of thromboelastography presented here, in addition to advantages compared with laboratory coagulation tests, position thromboelastography as an important opportunity for optimizing diagnosis of CAC and improving patient management in COVID-19. | 2021-02-03 |
| 33530357 | We show that a pre-existing diagnosis of Alzheimer’s disease predicts the highest risk of COVID-19 and mortality among elderly individuals. | 2021-02-03 |
| 33530550 | Also, we reviewed possible perspectives of using it as a dual cardio-inflammatory biomarker, for both early diagnosis, risk stratification and prognosis assessment of patients with concomitant HF and COVID-19. | 2021-02-03 |
| 33530822 | Secondary endpoints included incidence of extravasation, hyperglycemia, hypotension, and diagnosis of CLABSI/bacteremia. | 2021-02-03 |
| 33531037 | Through the implementation of a presurgical clinical protocol consisting of a physical examination; a clinical survey inquiring about signs, symptoms, and epidemiological contact with suspected or confirmed cases; and presurgical isolation but not involving the performance of molecular or serological diagnostic tests, positive results were obtained with regard to the performance of low- and medium-complexity elective orthopedic surgeries in an early stage of the COVID-19 pandemic. | 2021-02-03 |
| 33531454 | Diagnosis of Wellens often includes coronary angiography; however, during the current pandemic, many authorities have recommended medical management alone during the acute phase of care, depending on the severity of concomitant illness. | 2021-02-03 |
| 33531605 | The accurate and prompt diagnosis of SARS-CoV-2 infection is required for the control and treatment of the coronavirus infection disease 2019 (COVID-19). […] These results suggest that if the number of days since disease onset is taken into consideration, these antibody tests could be very useful for the diagnosis of COVID-19 and similar diseases. | 2021-02-03 |
| 33531720 | The research agenda proposes some new innovative approaches to capture and exploit new data sources using modern analytical techniques, like artificial intelligence, machine learning, and macro-data inputs, with the aim of providing enhanced predictive results. | 2021-02-03 |
| 33531721 | Early diagnosis and ultrahigh sample throughput screening are the need of the hour to control the geological spread of the COVID-19 pandemic. […] In this context, the point of care (PoC) diagnostic platform has proven to be the prospective approach in addressing the abovementioned challenges. […] This review emphasizes the mechanism of viral infection spread detailing the host-virus interaction, pathophysiology, and the recent advances in the development of affordable PoC diagnostic platforms for rapid and accurate diagnosis of COVID-19. […] Subsequently, the recent advances in the development of PoC biosensors, including lateral flow immunoassays and other emerging techniques, are highlighted. […] Finally, a focus on integrating nanotechnology with wearables and smartphones to develop smart nanobiosensors is outlined, which could promote COVID-19 diagnosis accessible to both individuals and the mass population at patient care. | 2021-02-03 |
| 33531833 | Pain symptoms present important challenge to clinicians’ diagnosis when treating COVID-19 patients with mild symptoms. […] Therefore, the summary of pain symptoms for COVID-19 patients can help doctors improve the accuracy and efficiency of diagnosis when treating COVID-19 patients with atypical or mild symptoms and adopt more targeted treatment methods. | 2021-02-03 |
| 33532006 | The diagnostic accuracy was comparable in all three assays (AUC 0.98). […] Although the diagnostic accuracy of the three investigated assays is comparable, their performance in low-prevalence settings is different. | 2021-02-03 |
| 33532151 | In developing countries, it is often associated with late diagnosis and high morbidity and mortality. | 2021-02-03 |
| 33532160 | He received a tentative diagnosis of COVID-19-induced pneumonia accompanied by severe acute respiratory distress syndrome (ARDS) and underwent urgent tracheal intubation and mechanical ventilation. | 2021-02-03 |
| 33532344 | Otorhinolaryngologists and head-neck surgeons must by now keep this diagnostic option in mind when evaluating cases of non-specific anosmia and ageusia that arose suddenly and are not associated with rhinitis/influenza symptoms. | 2021-02-03 |
| 33532346 | Retrospective study of tracheostomy in ten Covid-19 patients with ARDS using modifications of the surgical techniques revealed its efficacy in limiting the risks of spread to health care workers and improving surgical outcome. | 2021-02-03 |
| 33532374 | Such a simple modification can be useful in periphery wherein doctors are still not available and the growing number of patients would require a diagnosis of the chest conditions. | 2021-02-03 |
| 33532377 | All these considerations demand reviewing the treatment duration, discharge criteria, appropriate use of imaging techniques and importance of risk communication and health education to those recovered. | 2021-02-03 |
| 33532415 | This study aims to identify possible factors causing delay and losing precious time during diagnosis and treatment of COVID-19 at home and health facility level. […] It also aims to highlight perceptions and experiences of family members of deceased regarding diagnosis and treatment of COVID-19 infection in hospital. […] Socio demographic profile, sequence of events including clinical symptoms, medical aid taken, time of confirmation of diagnosis and treatment before death were noted from the records on a predesigned proforma. […] Median time from appearance of first symptom to first medical contact and confirmation of diagnosis was 1 and 5 days, respectively. […] On the basis of interview with deceased’s relative, various themes like delay in diagnosis and treatment, dissatisfied with hospital system and lack of communication between relative and patient were generated. | 2021-02-03 |
| 33532600 | Delay in cancer diagnosis will increase the stage progression of cancer patients and increased mortality in the future. | 2021-02-03 |
| 33532601 | Delay in cancer diagnosis will increase the stage progression of cancer patients and increased mortality in the future. | 2021-02-03 |
| 33532670 | Using electronic medical records from the second largest dialysis network in Guatemala, we performed a retrospective analysis of all adult patients on hemodialysis with the diagnosis of COVID-19 to estimate incidence of infection, and describe the demographics, comorbidities, and outcomes. | 2021-02-03 |
| 33532701 | We further discuss the emerging evidence supporting the use of 1) the non-invasive stimulation of vagus nerve as an additional therapeutic approach for severe COVID-19, and 2) the demonstrated vagal tone index, i.e., heart rate variability, via smartphone-based applications as a non-serological low-cost diagnostic of COVID-19. | 2021-02-03 |
| 33532847 | Resolving the coronavirus disease 2019 (COVID-19) pandemic requires diagnostic testing to determine which individuals are infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). | 2021-02-03 |
| 33533071 | Functions attributed to long non-coding RNAs (lncRNAs) make them highly attractive diagnostic and therapeutic targets in fibroproliferative diseases. […] Finally, we propose the potential approach of lncRNA-based diagnosis and therapy for pulmonary fibrosis. | 2021-02-03 |
| 33533105 | Immediate and accurate diagnosis of these scenarios is crucial to initiate the appropriate interventions. | 2021-02-03 |
| 33533210 | Amid a growing number of SARS-CoV-2 cases imported to Moscow in March 2020, the HCoV detection frequency dropped sharply, which can be explained by the competition between different coronaviruses and by the specificity of HCoV detection with the diagnostic test kit used in this study. | 2021-02-03 |
| 33533250 | Enhanced removal was attributed to the high hydrophobicity of ϕ6 imparted by its characteristic phospholipid envelope. ϕ6 adhesion to freshly precipitated iron (hydr)oxide also led to envelope damage causing inactivation in both coagulation techniques. | 2021-02-03 |
| 33533501 | Screening was suspended for at least 30 days in 13 countries, while diagnostic-services for screen-positives were suspended in 9 countries. […] A rating of ≤50 was given for screening services by 61.1%, diagnostic services by 44.4% and treatment services by 22.2% participants. | 2021-02-03 |
| 33533805 | Articles with children and/or adolescents with laboratory diagnosis of COVID-19 were used. thirty-two articles were included in the review. | 2021-02-03 |
| 33533822 | Identifying a bed bug during consultation is an uncommon feature that can help determine a particular diagnosis. | 2021-02-03 |
| 33533872 | Considering all types of diagnosis, there was no significant difference between the two groups (P = 0.261). | 2021-02-03 |
| 33533911 | There is scarce information about the performance of those visits. to compare telephone visits during the COVID-19 lockdown period with previous in-person visits. retrospective descriptive study. telephone visits from 15 March to 31 May 2020 were compared with in-person visits during the same period in 2019. the proportions of both groups were compared in term of failure to contact patient, requested diagnostic tests/referrals, discharges, admissions, and emergency visits within 30-60 days. | 2021-02-03 |
| 33533933 | To evaluate the association between HIV diagnosis and COVID-19 diagnosis, hospitalization, and in-hospital death in New York State. […] Diagnosis of HIV infection through December 31, 2019. […] The main outcomes were COVID-19 diagnosis, hospitalization, and in-hospital death. […] A total of 2988 persons living with diagnosed HIV (2109 men [70.6%]; 2409 living in New York City [80.6%]; mean [SD] age, 54.0 [13.3] years) received a diagnosis of COVID-19. […] After standardization, persons living with diagnosed HIV and persons living without diagnosed HIV had similar diagnosis rates (sRR, 0.94 [95% CI, 0.91-0.97]), but persons living with diagnosed HIV were hospitalized more than persons living without diagnosed HIV, per population (sRR, 1.38 [95% CI, 1.29-1.47]) and among those diagnosed (sRR, 1.47 [95% CI, 1.37-1.56]). […] Among persons living with diagnosed HIV, non-Hispanic Black individuals (aRR, 1.59 [95% CI, 1.40-1.81]) and Hispanic individuals (aRR, 2.08 [95% CI, 1.83-2.37]) were more likely to receive a diagnosis of COVID-19 than White individuals, but they were not more likely to be hospitalized once they received a diagnosis or to die once hospitalized. […] In this cohort study, persons living with diagnosed HIV experienced poorer COVID-related outcomes relative to persons living without diagnosed HIV; Previous HIV diagnosis was associated with higher rates of severe disease requiring hospitalization, and hospitalization risk increased with progression of HIV disease stage. | 2021-02-03 |
| 33533965 | While the primary diagnostic test for COVID-19 is the reverse transcriptase-polymerase chain reaction (RT-PCR) assay, chest CT has proven to be a diagnostic tool of high sensitivity. […] Radiologists and physicians should be aware of imaging patterns of these conditions to prevent an erroneous diagnosis that could adversely influence management and patients’ outcome. | 2021-02-03 |
| 33534308 | The authors present an 84-year-old male with atypical skull base osteomyelitis that developed from otitis media during the COVID-19 pandemic due to delayed diagnosis and partial treatment which is blamed for development of skull base osteomyelitis. […] The atypical presentations of skull base osteomyelitis pose a diagnostic challenge. […] Early diagnosis and aggressive management of skull base osteomyelitis are of upmost importance and will ensure a more favorable prognosis. | 2021-02-03 |
| 33534752 | We report on a set of pragmatic recommendations for microbiology and laboratory testing, imaging, and the use of diagnostic and prognostic models in patients with severe COVID-19 in LMICs. […] For diagnostic testing, where reverse transcription-PCR (RT-PCR) testing is available and affordable, we recommend using RT-PCR of the upper or lower respiratory specimens and suggest using lower respiratory samples for patients suspected of having COVID-19 but have negative RT-PCR results for upper respiratory tract samples. […] Where available, we recommend the use of point-of-care antigen-detecting rapid diagnostic testing for SARS-CoV-2 infection as an alternative to RT-PCR, only if strict quality control measures are guaranteed. […] We currently suggest against using diagnostic and prognostic models as these models require extensive laboratory testing and imaging, which often are limited in LMICs. | 2021-02-03 |
| 33534775 | Rapid diagnosis and timely intervention are crucial to ensure good patient outcomes. | 2021-02-03 |
| 33534813 | A total of 800 patients were admitted with confirmed diagnosis, mean age was 51.9 ± 13.9 years, 61% were males, 85% were either obese or overweight, 30% had hypertension and 26% type 2 diabetes. | 2021-02-03 |
| 33534838 | Lastly, end-point fluorescence imaging is found to provide an accurate diagnostic readout without requiring a qPCR thermocycler. | 2021-02-03 |
| 33534949 | We propose that scarce testing resources should be diverted away from confirmatory analysis of symptomatic people, as laboratory diagnosis appears to have little decision value in treatment choice over clinical diagnosis in patients presenting with symptoms. | 2021-02-03 |
| 33535007 | Cerebrospinal fluid was suggestive for GBS despite the electrodiagnostic test was not helpful because it was done in the first days. | 2021-02-03 |
| 33535011 | To our knowledge, this is the first description of a delayed onset cell-mediated encephalitis caused by COVID-19 virus after more than 40 days from the diagnosis. | 2021-02-03 |
| 33535120 | These were compared to those observed in 579 patients admitted in the first wave, between February 24th and April 26th 2020, by means of Cox regression techniques adjusted for age, sex and weight. | 2021-02-03 |
| 33535237 | These data showed that both techniques are equally sensitive in detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) providing additional value of DETECTR to the currently used qRT-PCR platforms. […] Because there is no need for specialized equipment, DETECTR could be rapidly implemented as a complementary technically independent approach to qRT-PCR thereby increasing the testing capacity of medical microbiological laboratories and relieving the existent PCR platforms for routine non-SARS-CoV-2 diagnostic testing. | 2021-02-03 |
| 33535238 | Notably, a novel serological test for antibodies against the receptor binding domain of SARS-CoV-2 showed that 100% of our asymptomatic cohort remained seropositive 3-6 weeks after diagnosis. | 2021-02-03 |
| 33535520 | Clinicians should have a low threshold for testing for COVID-19 in older and frail patients during periods of community viral transmission, and diagnosis should prompt early advanced care planning. | 2021-02-04 |
| 33535813 | The ongoing pandemic has demonstrated the utility of widespread surveillance and diagnostic detection of the novel SARS-CoV-2. | 2021-02-04 |
| 33535814 | Smell loss is important for coronavirus disease-2019 (COVID-19) screening and diagnosis. | 2021-02-04 |
| 33535916 | Other telemedical interventions included videoconferencing for peri-operative visits, diagnosis of peritonsillar abscess, telephone-based voice evaluations and evaluation of nasal fractures. | 2021-02-04 |
| 33535945 | To eradicate conventional time consuming steps like quantitative real time polymerase chain reaction for detection of COVID-19, nanoparticles mediated sensing approaches is providing a great advances in rapid diagnosis. […] Nano particles based biosensors are comparatively beneficial which offer tremendous potential for rapid medical diagnosis. | 2021-02-04 |
| 33536083 | Prospective, formative, pragmatic evaluation using both quantitative and qualitative techniques and driven by implementation science theoretical frameworks. | 2021-02-04 |
| 33536114 | We reported of a 55-year-old woman with a diagnosis of severe asthma for; 3 years and who was being treated withmepolizumab, with no evidence of loss of asthma control, at the time of contracting COVID-19 and who had been followed up inthe allergy clinic. | 2021-02-04 |
| 33536218 | SARS-CoV-2 infection has a distinct biosignature that differs between NP swabs and WB and can be leveraged for COVID-19 diagnosis. | 2021-02-04 |
| 33536436 | Of these, 102,002 had an outpatient diagnosis of COVID-19, 16,901 were hospitalised with COVID-19, and 5273 died after either being diagnosed or hospitalised with COVID-19 between 1st March and 6th May 2020. | 2021-02-04 |
| 33536446 | The large majority of individuals with SMI in this outpatient sample, regardless of broad diagnostic category, reported performing multiple behaviors intended to prevent COVID-19 infection at least once a month and reported distress associated with the pandemic. | 2021-02-04 |
| 33536460 | This study aims to analyze the clinical characteristics of COVID-19 ARDS patients and establish a diagnostic system based on artificial intelligence (AI) method to predict the probability of ARDS in COVID-19 patients. | 2021-02-04 |
| 33536572 | There is an urgent and unprecedented need for sensitive and high-throughput molecular diagnostic tests to combat the SARS-CoV-2 pandemic. | 2021-02-04 |
| 33536760 | Rapid severe acute respiratory syndrome coronavirus 2 test kits are crucial for bridging diagnostic gaps in health facilities and community screening mainly in resource limited settings. […] However, there is no objective evidence on their diagnostic performance. […] Thus, the study aimed to evaluate comparative diagnostic performance of three selected SARS-CoV-2 IgG/IgM rapid test kits in Ethiopia. […] Test kits showed a heterogeneous comparative diagnostic performance in their sensitivity and specificity. […] There was a significant difference on diagnostic performance among the three test kits and PCR with a p-value < 0.001 Cochran’s Q test. […] The diagnostic performance of the test kits was promising and recommended for COVID-19 diagnostics in combination with RT-PCR to detect more infected patients. […] We underline countries to evaluate rapid diagnostic test kits before diagnostic use. | 2021-02-04 |
| 33536999 | 7/606 PwP (1.15%) reported COVID-19 related symptoms, 4/606 (0.66%) underwent a rRT-PCR-based diagnostic test and 2/606 (0.33%) were confirmed as SARS-CoV-2 positive. | 2021-02-04 |
| 33537150 | We identify a variety of techniques that they deployed either to minimize, rationalize, justify or excuse deviations from the relevant public health rules. | 2021-02-04 |
| 33537246 | Unfortunately, the COVID-19 pandemic in Italy has led to a diagnostic delay of several malignancies and the impact of this delay has likely been underestimated. […] We present this case for its histological rarity and to document a case of diagnostic and therapeutic delay during the pandemic in Lombardy. | 2021-02-04 |
| 33537322 | In this note we analyze the problems in the nucleic acid testing (NAT) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and we also give some suggestions for improving the accuracy of NAT diagnosis. […] NAT testing is considered to be the diagnostic “gold standard”; at present there are few reviews on NAT for SARS-CoV-2. […] Moreover, many false-negative results always appear in the procedure of detecting, which has affected early diagnosis of the disease and brought a great challenge to mitigation and containment of the pandemic. […] In conclusion, comprehensive analyses of serological and imaging findings should be performed to guide the formulation of an accurate clinical diagnosis, treatment plan, and monitoring therapeutic efficacy, in an effort to achieve early diagnosis, containment, and treatment of the disease, thereby effectively reducing progression of the pandemic. | 2021-02-04 |
| 33537326 | An OS nomogram for the clinical diagnosis and treatment of COVID-19 was constructed using biomarkers. […] These data will be useful for the diagnosis, management, and therapy of COVID-19. | 2021-02-04 |
| 33537362 | Of the 590 HCWs included in the cohort, 134 (22%) were asymptomatic at diagnosis, and 15% (89 patients) remained asymptomatic during follow-up. […] Active screening for SARS-CoV-2 among HCWs for early diagnosis and stopping in-hospital transmission chains proved efficacious in our institution, particularly due to the high percentage of asymptomatic HCWs. | 2021-02-04 |
| 33537365 | Coronavirus disease 2019 and PCP co-occurrence is increasingly reported and may complicate diagnostic and therapeutic strategies. | 2021-02-04 |
| 33537687 | Subsequently, due to the disordered metabolic state of tumor cells, applications of Met in cancer treatment and diagnosis are summarized in detail. | 2021-02-04 |
| 33537862 | This is a narrative review on the recent state of the prevalence, mechanism, and diagnostic and therapeutic strategy of chemosensory dysfunction in COVID-19 patients during the global pandemic. […] Several suggestions on the diagnosis and treatment of COVID-19 patients with smell and taste disorders were summarized for the physicians. | 2021-02-04 |
| 33538019 | People of any age who had provided blood for testing at selected diagnostic pathology services (general pathology); pregnant women aged 20-39 years who had received routine antenatal screening; and Australian Red Cross Lifeblood plasmapheresis donors aged 20-69 years. | 2021-02-04 |
| 33538037 | Herein, the most promising strategies reported in the literature on the use of GRM-based materials against the COVID-19 pandemic and other types of viruses are showcased, with a strong focus on the impact of functionalization, deposition techniques, and integration into devices and surface coatings. | 2021-02-04 |
| 33539175 | We collected data on their breast cancer diagnosis, comorbidity, and demographic characteristics. | 2021-02-04 |
| 33539260 | This review seeks to describe the targets and diagnostic methods available or currently in development for SARS-CoV-2 infection, including reverse transcription PCR (RT-PCR), serologic immunoassays (SIA) and the protein microarray method (PMM). […] Knowing the specific targets and the sensitivity of each assay used for COVID-19 diagnosis can lead to more efficient detection of infected patients and it can provide better management of the pandemic status. | 2021-02-04 |
| 33539306 | Lockdowns and shelter-in-place orders during the COVID-19 pandemic have accelerated the adoption of remote and virtual care (RVC) models, which may include telehealth, telemedicine, internet-based electronic doctor visits (e-visits) for remote consultation, diagnosis, and care. | 2021-02-04 |
| 33539312 | Among the 5,594 patients included in this analysis, 234 died after COVID-19 diagnosis. | 2021-02-04 |
| 33539474 | To minimize sample dilution effect on SARS-CoV-2 pool testing, we assessed analytical and diagnostic performance of a new methodology, namely swab pooling. | 2021-02-04 |
| 33539485 | We now report the comparative performance of five real-time diagnostic assays. […] Nasopharyngeal swab samples were obtained from persons seeking a diagnosis for SARS-CoV-2 infection in Lagos, Nigeria. […] The varied performance of different diagnostic assays, mostly with emergency use approvals, for a novel virus is expected. | 2021-02-04 |
| 33539583 | Differential diagnosis with tumor- or treatment-related symptoms is always required to avoid unnecessary delays. […] A questionnaire-based triage has a low positive predictive value to triage patients with cancer and suspected SARS-CoV-2 symptoms, and a differential diagnosis with tumor- or treatment-related symptoms is mandatory to avoid unnecessary treatment delays. | 2021-02-04 |
| 33539644 | We describe a “don’t touch the bowel technique”, outline the benefits to patients of the use of less surgically aggressive techniques and also to surgeons in terms of the lower emission of aerosols that might transmit the COVID19 infection. | 2021-02-04 |
| 33539721 | CAPA was diagnosed a median of 10 days after coronavirus disease diagnosis. | 2021-02-04 |
| 33539846 | Limitations of the gold standard qRT-PCR for diagnosis of this infection includes need for expensive equipment, specialized molecular laboratory, and experienced staff. […] Currently, CRISPR-based diagnostic method was approved by the U.S. […] Therefore, this study evaluated the clinical performance of previously described CRISPR-Cas12a based diagnostic assays for SARS-CoV-2. […] According to the results, the CRISPR-Cas12a assays on N1 and S genes provided diagnostic accuracy (≥ 95 %) comparable to the qRT-PCR results. | 2021-02-04 |
| 33540131 | It enables health professionals to accurately identify frauds related to physician educational credentials and medical testing kits commonly used for home-based diagnosis. | 2021-02-04 |
| 33540323 | Prompt diagnosis, patient isolation, and contact tracing are key measures to contain the coronavirus disease 2019 (COVID-19). […] Here we describe a portable assay system for rapid, onsite COVID-19 diagnosis. | 2021-02-04 |
| 33540335 | The American Heart Association’s ‘Get with the Guidelines’ (GWTG) database was used to evaluate the following categories: code stroke, diagnosis of stroke upon discharge, inpatient mortality, modified Rankin Score (mRS) upon discharge (morbidity), and time since last known well (LKW). | 2021-02-04 |
| 33540410 | We performed a timely analysis of ischemic stroke (IS) and related consultations using the telestroke TEMPiS “working diagnosis” database prior (PL), within (WL), and after easing (EL) of CPL. | 2021-02-04 |
| 33540596 | The viral genome was sequenced in seven serial samples and in the diagnostic sample from her infected mother. […] The 20A lineage was absolute at the diagnosis (shared with the patient’s mother), but nine days later, the 20B lineage had 3% frequency, and two months later, the 20B lineage had 100% frequency. | 2021-02-05 |
| 33541033 | This study evaluated the diagnostic value of the various symptoms of COVID-19 in the screening of this disease. […] The methodological quality of included studies was evaluated using the Quality Assessment of Diagnostic Accuracy Studies tool (ver. […] The diagnostic odds ratio (DOR) of a change in olfaction and/or taste was 10.20 (95% confidence interval [CI], 8.43; 12.34). […] Olfactory and/or taste changes had a higher diagnostic value than the other otolaryngologic symptoms, a higher DOR and specificity, and a similar or higher diagnostic value than the other general symptoms. | 2021-02-05 |
| 33541492 | To analyze the clinical and laboratory characteristics of coronavirus disease 2019 (COVID-19) patients with different prognosis, and to provide evidence for the diagnosis and treatment of COVID-19. […] The changes of laboratory indexes of COVID-19 group and control group were observed. were significantly higher than those in control group. , also have important value in the differential diagnosis between COVID-19 and other viral pneumonia. | 2021-02-05 |
| 33541953 | Further diagnostic work-up confirmed the diagnosis of idiopathic hypereosinophilic syndrome (iHES), a rare myeloproliferative disease with a heterogeneous clinical presentation. […] This case accentuates the importance of an extensive multidisciplinary diagnostic work-up, since iHES is a condition with potential rapid progressive multiorgan failure which requires prompt analysis and treatment. | 2021-02-05 |
| 33542109 | There has been a significant impact on the provision of both diagnostic and therapeutic services in North-West of Ireland due to the COVID-19 pandemic. | 2021-02-05 |
| 33542424 | Standard molecular diagnostic laboratory equipment, and commercially available centrifugal filters, RNA isolation kits and SARS Cov2 PCR tests were used. | 2021-02-05 |
| 33542443 | We also tested the utility of next-generation sequencing (NGS) for diagnosis of COVID-19. […] We found saliva to be a sensitive and viable sample for COVID-19 diagnosis. | 2021-02-05 |
| 33542473 | Despite only relying on previously documented demographics and comorbidities, our models demonstrated similar performance to other prognostic models that require an assortment of symptoms, laboratory values, and images at the time of diagnosis or during the course of the illness. | 2021-02-05 |
| 33542609 | Based on the clinical history and findings in our patient, a diagnosis of optic neuropathy due to accidental ingestion of sanitizer containing methyl alcohol as an unlisted ingredient was made. | 2021-02-05 |
| 33542626 | Serological tests are an important method to assist in the diagnosis of COVID-19, used for epidemiological investigations. | 2021-02-05 |
| 33542825 | These changes have already impacted the dynamics of patient care and might lead to a risk of diagnostic delays which will have severe impacts on patient’s health. | 2021-02-05 |
| 33542878 | Methods We identified 235 patients who were admitted to our Hospital in NYC between March 19th and April 25th, 2020 with laboratory confirmed COVID-19 diagnosis with associated pneumonia and who also had documented inflammatory markers (D-dimer, C-reactive protein, lactate dehydrogenase, ferritin, procalcitonin) during their hospital stay. | 2021-02-05 |
| 33542972 | Early echocardiographic diagnosis of high-risk PE related to right heart thrombus was performed. | 2021-02-05 |
| 33543178 | Considering this, the rapid screening and accurate detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; 2019-nCoV) play an essential role in the diagnosis of COVID-19, which can minimize local transmission and prevent an epidemic. […] Due to this public health emergency, the development of ultra-fast reliable diagnostic kits is essential for the diagnosis of COVID-19. […] Recently, molecular biology and nanotechnology based analytical methods have proven to be promising diagnostic tools for the rapid screening of 2019-nCoV with high accuracy and precision. […] The main aim of this review is to provide a retrospective overview on the molecular biology tools (reverse transcription polymerase chain reaction (RT-PCR) and reverse transcription loop-mediated isothermal amplification (RT-LAMP)) and nanotechnology based analytical tools (enzyme-linked immunosorbent assay (ELISA), RT-PCR, and lateral flow assay) for the rapid diagnosis of COVID-19. […] This review also presents recent reports on other analytical techniques including paper spray mass spectrometry for the diagnosis of COVID-19 in clinical samples. […] Finally, we provide a quick reference on molecular biology and nanotechnology based analytical tools for COVID-19 diagnosis in clinical samples. | 2021-02-05 |
| 33543225 | The categories of information most concerned by all respondents was data such as the number of newly diagnosed patients and the number of cured cases, followed by the diagnosis and treatment of patients with COVID-19. | 2021-02-05 |
| 33543233 | Antimicrobial stewardship programs faced diagnostic and therapeutic uncertainties as well as healthcare resource challenges. | 2021-02-05 |
| 33543254 | Individual and serial samples covered the time of initial diagnosis, during the disease course, and following recovery. | NA |
| 33543338 | SARS-CoV-2 PCR confirmed the COVID-19 diagnosis. […] Through a systematic search of the medical literature, we retrieved two cases with newly onset SLE and five cases with previous SLE diagnosis that showed activity of the disease due to SARS-CoV-2 infection. […] We herein present a systemic review of these cases and discuss the clinical manifestations that could help to the diagnosis of this clinical condition. | 2021-02-05 |
| 33543434 | This is the first study that attempts to examine the nexus between the confirmed COVID-19 cases, deaths, meteorological factors, and the air pollutant namely PM2.5 in six South Asian countries, from 1 March 2020 to 30 June 2020, using the advanced econometric techniques that are robust to heterogeneity across nations. | 2021-02-05 |
| 33543440 | However, further studies are necessary to improve this instrument, adding new questions useful for the diagnosis and evaluation of cigarette dependence. | 2021-02-05 |
| 33544258 | We investigated the association between RRI and AKI diagnosis, different AKI stages and urine output. | 2021-02-05 |
| 33544506 | This is because of many reasons which include the atypical presentation in the geriatric population which might have led to diagnostic delay. | 2021-02-05 |
| 33544518 | We enrolled consecutive patients with confirmed diagnosis of COVID-19 admitted to Medical Departments (MD) or Intensive Care Units (ICU), and 54 healthy controls. […] COVID-19 patients showed increased TG at diagnosis. | 2021-02-05 |
| 33544531 | The secondary aim is to analyze the diagnostic value of hematologic parameters in COVID-19 complicated pregnancies. […] ROC analysis revealed that the optimal cut-off value for MLR was 0.354 which indicated 96.7% specificity and 59.5% sensitivity in diagnosis of pregnant women with COVID-19. […] MLR may serve as a supportive diagnostic parameter together with the Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) in assessment of COVID-19 in pregnant cohort. | 2021-02-05 |
| 33544647 | Laboratory testing is an important component in the diagnosis of respiratory tract infections such as with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). […] The goals of this article are to highlight the literature regarding self-collected nasal or oropharyngeal specimens for respiratory pathogen testing; discuss the role of self-collection in helping prevent the spread of the COVID-19 disease from infected patients and facilitating a shift toward “virtual” medicine or telemedicine; and describe the current and future state of self-collection for infectious agents, and the impacts these approaches can have on population health management and disease diagnosis and prevention. | 2021-02-05 |
| 33544690 | We used machine learning techniques and longitudinally analyzed a total of 46,732 English YoutTube comments that were retrieved from 57 videos of PM Trudeau’s COVID-19 daily briefings from March 13 to May 22, 2020. | 2021-02-05 |
| 33544857 | Recovered COVID-19 patients. 782 patients with a confirmed diagnosis of COVID-19 infection. | 2021-02-05 |
| 33544876 | These findings suggest that vulnerable older adults can mount an antibody response to SARS-CoV-2, and that antibodies are most likely to be detected within 15-30 days of diagnosis. […] Frequent surveillance and diagnostic testing based on low thresholds of clinical suspicion for symptoms and/or exposure will remain critical to inform strategies designed to mitigate outbreaks in SNFs while community SARS-CoV-2 prevalence remains high. | 2021-02-05 |
| 33544999 | Current main-stream diagnostic methods in the laboratory include nucleic acid PCR tests and direct viral antigen tests for detecting active infections, and indirect human antibody tests specific to SARS-CoV-2 to detect prior exposure. […] False negatives in antibody immunoassays can arise from assay formats, selection of viral antigens and antibody types, diagnostic testing windows, individual variance, and fluctuation in antibody levels. | 2021-02-05 |
| 33545052 | Second, we provide empirical evidence of the high propensity for antibody cross-reactivity between distinct strains of human coronaviruses, which is critical information for designing diagnostic and vaccine strategies for COVID-19. | 2021-02-05 |
| 33545157 | Since this pandemic began, extraordinary efforts have been made by scientists to understand the pathogenesis of COVID-19, and to fight the infection by providing various preventive, diagnostic and treatment opportunities based on either novel hypotheses or past experiences. | 2021-02-05 |
| 33545240 | A prospective, single-centre study enrolling 743 symptomatic patients referred for a diagnostic colonoscopy. […] The EPAGE guidelines, unlike the iFOBT, is not suitable for screening candidate patients for a diagnostic colonoscopy to detect CRC. | 2021-02-05 |
| 33545516 | Generalized mixed models were used to calculate the accuracy of vital parameters for detection of COVID-19 and to evaluate the diagnostic accuracy of CT. | 2021-02-05 |
| 33545517 | This paper aims to review the most recent medical imaging techniques used for the diagnosis of SARS-CoV-2 and their potential contributions to attenuate the pandemic. […] We review the main clinical features of SARS-CoV-2 revealed by different medical imaging techniques. […] Then, we describe several artificial intelligence approaches introduced for the SARS-CoV-2 diagnosis. […] CT is the most accurate diagnostic modality of SARS-CoV-2. […] The identification of SARS-CoV-2 manifestations on medical images is a key step in radiological workflow for the diagnosis of the virus and could be useful for researchers working on computer-aided diagnosis of pulmonary infections. | 2021-02-05 |
| 33545551 | In summary, the development of RT-Proofman-LAMP offers a versatile and highly-specific method for fast field screening and laboratory testing of SARS-CoV-2, making it a promising platform in COVID-19 diagnosis. | 2021-02-05 |
| 33545652 | During the visits, 39% of patients had their anticonvulsants adjusted while 18.8% and 11.2% were referred to laboratory/diagnostic testing and specialty consults, respectively. | 2021-02-05 |
| 33546319 | ML algorithms were applied to the collected data to predict a COVID-19 diagnosis using a 50-fold cross-validation scheme by randomly splitting the patients in training (75%) and testing datasets (25%). […] The ML algorithms applied reached an average accuracy of 80%, a sensitivity of 82%, and a specificity of 78% when using VAS to predict a COVID-19 diagnosis. […] This study concludes that smell and taste disorders are accurate predictors, with ML algorithms constituting helpful tools for COVID-19 diagnostic prediction. | 2021-02-06 |
| 33546341 | IgM assays have variable and low sensitivity, thus considered a poor marker for COVID-19 diagnosis. | 2021-02-06 |
| 33546527 | Patients were clinically classified according to disease severity as per ‘Diagnosis And Treatment Program of Pneumonia of New Coronavirus Infection’ recommended by China’s National Health Commission. | 2021-02-06 |
| 33546624 | Two biomedical databases were searched between September 2019 and June 2020 for case reports and series of pregnant women with a diagnosis of COVID-19 based either on a positive swab or high clinical suspicion where no swab had been performed. | 2021-02-06 |
| 33546639 | So that with early diagnosis and intervention mortality in COVID-19 patients may be reduced. | 2021-02-06 |
| 33546658 | This is a multihospital retrospective cohort study on 1871 adult patients between March 10, 2020, and June 30, 2020, with laboratory confirmed COVID-19 diagnosis. | 2021-02-06 |
| 33546734 | Adults who are admitted to hospital within the McGill University Health Centre systems (MUHC) including Royal Victoria Hospital (RVH), Montreal General Hospital (MGH) and Jewish General Hospital (JGH) and who are within 96 hours of COVID-19 diagnosis (confirmed via PCR on any biological sample) will be considered for the trial. […] Of note, the initial protocol to screen and enrol within 48 hours of COVID-19 diagnosis was extended through an amendment, to 96 hours to increase feasibility. […] Once a patient is admitted on the ward with a diagnosis of COVID-19, we will confirm with the treating physician if the participant is suitable for the RAAS-COVID trial and meets all the inclusion and exclusion criteria. | 2021-02-06 |
| 33546738 | This review contains replicable and widely usable instructions on how to avoid delays in the diagnosis and treatment of head and neck tumors and to ensure a gradual return to elective procedures. […] The Head and Neck Department of the research hospital “Casa Sollievo della Sofferenza” includes an Otolaryngology and a Maxillofacial Surgery Unit, both of which deal with the diagnosis and treatment of benign and malignant pathologies of the head and neck, as well as urgent/emergent consultations and surgical procedures that necessitate time sensitive operative management, such as cochlear implantation (CI). | 2021-02-06 |
| 33546881 | Here, we present a healthy young male, with presumed acute myocarditis, presenting 20 days after initial diagnosis of COVID-19 - and after a clinical, and apparent laboratory, resolution of the original episode. | 2021-02-06 |
| 33546959 | This novel SARS-CoV-2 antigen detection assay is highly sensitive, rapid, accurate, easily diagnostic. […] It may be useful in both clinical diagnosis and in screening because it does not require special methods such as PCR. | 2021-02-06 |
| 33547028 | For TB patients with COVID-19 the proportion of cases admitted is 58%, probably reflecting different scenarios related to the diagnosis of COVID-19 before, after or at the same time of the active TB episode. | 2021-02-06 |
| 33547029 | The available evidence on clinical aspects suggests that COVID-19 happens regardless of TB occurrence either before, during or after an active TB diagnosis. | 2021-02-06 |
| 33547323 | Diagnosis of COVID-19 depends on quantitative reverse transcription PCR (qRT-PCR), which is time-consuming and requires expensive instrumentation. […] In summary, this biosensor could be used as an on-site, real-time diagnostic test for COVID-19. | 2021-02-06 |
| 33547335 | The ML models predicted the risk of death (Receiver Operation Characteristics-Area Under the Curve, ROC-AUC) of 0.906 at diagnosis, 0.818, at hospital admission and 0.721 at Intensive Care Unit (ICU) admission. | 2021-02-06 |
| 33547610 | This paper examines the nexus between the Covid-19 confirmed cases, deaths, meteorological factors, including an air pollutant among the world’s top 10 infected countries, from 1 February 2020 through 30 June 2020, using advanced econometric techniques to address heterogeneity across the nations. | 2021-02-06 |
| 33547747 | Beyond its contribution at the emergency department, CD169 testing may be also helpful for patients’ triage at the ICU to rapidly reinforce suspicion of COVID-19 etiology in patients with acute respiratory failure awaiting for PCR results for definitive diagnosis. | 2021-02-06 |
| 33547981 | Operative diagnosis; droplet count and distribution on plastic sheet and face shields of console and assistant surgeons, and scrub nurse were documented. | 2021-02-06 |
| 33548030 | Chronic liver disease (CLD) was confirmed by consensus diagnostic criteria. | 2021-02-06 |
| 33548044 | Patients were followed-up at least fifteen days or until death after COVID-19 diagnosis. […] All patients were reviewed retrospectively over a median follow-up of 44 days (IQR, 36-52) after diagnosis of COVID-19. | 2021-02-06 |
| 33548415 | Medicare reimbursement methodologies were utilized to assign financial value: Diagnosis-Related Group (DRG) for inpatient services, Ambulatory Payment Classification (APC) for outpatient services, and Medicare Physician Fee Schedule (MPFS) for professional reimbursement and work relative value units (wRVU). | 2021-02-06 |
| 33548660 | Overall, 64.8% met the level of clinical concern for posttraumatic stress disorder and 51.3% met the level of probable posttraumatic stress disorder diagnosis. | 2021-02-06 |
| 33548855 | To evaluate the diagnostic performances of four SARS-CoV-2 IgG antibody immunoassays. | 2021-02-06 |
| 33548891 | On the other hand, vaccination causes various confusing radiologic patterns that pose diagnostic challenges for clinicians and pitfalls for reading radiologists. | 2021-02-06 |
| 33548937 | Median gestational age at symptom onset or diagnosis was 36 weeks. | 2021-02-06 |
| 33549624 | Compared to the general population, adult CA and SOT patients with COVID-19 had higher comorbidities, greater levels of inflammatory markers at diagnosis, and higher rates of intensive care and hospital mortality. | 2021-02-07 |
| 33549828 | The most common aim of these interventions was emotional regulation, which was treated by psychoeducational and cognitive-behavioural techniques in individual interventions. […] Several hospitals in Spain have developed mental health interventions for healthcare workers during the COVID-19 pandemic, deploying a wide range of therapeutic modalities and techniques. | 2021-02-07 |
| 33550007 | The outbreak of COVID-19 around the world has caused great pressure to the health care system, and many efforts have been devoted to artificial intelligence (AI)-based analysis of CT and chest X-ray images to help alleviate the shortage of radiologists and improve the diagnosis efficiency. | 2021-02-07 |
| 33550068 | Medical imaging provides a non-invasive, touch-free, and relatively safer alternative tool for diagnosis during the current ongoing pandemic. […] Artificial intelligence (AI) scientists are developing several intelligent computer-aided diagnosis (CAD) tools in multiple imaging modalities, i.e., lung computed tomography (CT), chest X-rays, and lung ultrasounds. […] The novelty of this review is the approach to classifying the AI models as per the by school of thought (SoTs), exhibiting based on segregation of techniques and their characteristics. | 2021-02-07 |
| 33550101 | Visits were assigned to pre-determined diagnostic categories. | 2021-02-07 |
| 33550272 | Patient demographics, emergency classification, distribution of the main diagnostic groups (associated with complaints) and services provided via telemedicine were collected. […] In the case of several main diagnosis groups, significant therapy loss and a delayed need for care could be expected. | 2021-02-07 |
| 33550533 | Recently, a number of studies evaluating the diagnosis and treatment of DIC in COVID-19 patients have been reported. […] The aim of this study is to identify existing gaps where further research is needed on the diagnosis and treatment of DIC complicated by COVID-19. […] Studies on DIC diagnostic criteria and anticoagulants were limited to the ISTH or SIC scores and heparinoids, particularly LMWH. | 2021-02-07 |
| 33550678 | The medical files of all patients were reviewed retrospectively. ) at the time of diagnosis. | 2021-02-07 |
| 33550713 | Diagnosis of HIT requires confirmation of heparin-dependent, platelets activating antibodies to avoid overdiagnosis and overtreatment with non-heparin anticoagulants. | 2021-02-07 |
| 33550733 | From January 15 to March 3, 2020, seven editions of the guidelines for the diagnosis and treatment of COVID-19 have been issued successively by the National Health Commission of the People’s Republic of China, and the guidelines’ name was changed from Guidelines for Diagnosis and Treatment of Novel Coronavirus Pneumonia to Diagnosis and Treatment for COVID-19. […] It optimized and perfected the etiology, clinical manifestations and types, diagnostic procedures and specific treatment measures of the disease, so that the clinical management of the cases was more scientific. […] In the revision process of guidelines for diagnosis and treatment, forensic medicine experts have also made some positive suggestions on clinical diagnosis and treatment. | 2021-02-07 |
| 33550849 | From March 2 to May 24, 2020, 11,512 patients who were hospitalized were tested for COVID-19, with 4,446 (38.62%) receiving a positive diagnosis for COVID-19. | 2021-02-08 |
| 33550940 | The literature supports an initial increase in mental health concerns which generally do not reach the threshold for diagnosis with a mental illness, but present to frontline telephone services. | 2021-02-08 |
| 33550944 | Symptoms and tests in most cases lead to a correct diagnosis; however, error may be around the corner. […] Clinicians should consider other life-threatening disease in the differential diagnosis of patients presenting with similar symptoms to minimize mistakes and avoid further unnecessary investigations. | 2021-02-08 |
| 33550983 | Improving early diagnosis along with timely and effective treatment of COVID-19 are urgently needed. | 2021-02-08 |
| 33550984 | The main clinical outcomes will be clinical severity in obese patients with COVID-19 as tachypnea (respiratory rate, ≥ 30 breaths per minute), hypoxemia (oxygen saturation, ≤ 93%), the ratio of the partial pressure of arterial oxygen to fraction of inspired oxygen (< 300), lung infiltrate (> 50% of the lung field involved within 24-48 h), diagnosis of the severe acute respiratory syndrome, need of invasive mechanical ventilation, and mortality. | 2021-02-08 |
| 33551188 | The aim is to recommend a fast and cost-effective screening procedure for UK/SA SARS-CoV-2 variants in a routing diagnostic setting. | 2021-02-08 |
| 33551247 | In this case report, we describe the diagnosis and management of priapism as a thromboembolic complication of severe COVID-19. | 2021-02-08 |
| 33551317 | These data suggest that among patients with DTC, advanced age and comorbid conditions are significant contributors to the risk of hospitalization from SARS-CoV2 infection, rather than factors associated with thyroid cancer diagnosis, treatment, or disease burden. | 2021-02-08 |
| 33551422 | Thereafter, reverse transcription polymerase chain reaction performed on a preserved bronchial lavage sample tested positive, and thus his diagnosis was corrected to COVID-19 pneumonia. | 2021-02-08 |
| 33551505 | These components were: identification and diagnosis of close contacts; suspected cases and confirmed cases of COVID-19; treatment of COVID-19 cases; compulsory quarantine of close contacts and suspected cases; and productivity losses for all affected residents. | 2021-02-08 |
| 33551665 | In case of Diabetes, clinicians and experts are finding challenging the timely diagnosis and analyzing the chances of developing underlying diseases. […] Louvain Mani-Hierarchical Fold Learning healthcare analytics showed maximum 0.952 correlations between two clusters with Spearman when applied on 240 instances extracted from comorbidities diagnostic data model derived from 15696 endocrine records of multiple visits of 100 patients identified by a unique ID. […] Endocrine diagnostic data is made available by Shifa International Hospital, Islamabad, Pakistan. | 2021-02-08 |
| 33551668 | Of all the available methods, reverse-transcriptase polymerase chain reaction (RT-PCR) has been widely practiced for the pandemic detection even though several diagnostic tools are available having varying accuracy and sensitivity. […] This review will discuss about the available diagnostic methods and biosensors for COVID-19 detection. | 2021-02-08 |
| 33551864 | It is suggested that awareness regarding COVID-19 stressors, use of community-based approaches like gatekeeper training, and brief online psychotherapy by using techniques of mindfulness, interpersonal psychotherapy, and cognitive behavior therapy can be useful in reducing suicide risk during COVID-19. | 2021-02-08 |
| 33551979 | It also emphasizes the diagnostic value of early CT imaging and the need for effective treatment once thrombotic events occur. | 2021-02-08 |
| 33552326 | Since the widespread of acute respiratory syndrome infection caused by Coronavirus-19, chest computed tomography (CT) was considered a useful imaging tool commonly used in early diagnosis and monitoring of patients with complicated Covid-19 pneumonia. | 2021-02-08 |
| 33552370 | The diagnosis was confirmed after a positive RT-PCR test. […] The diagnosis was confirmed after a positive RT-PCR test. | 2021-02-08 |
| 33552373 | Incidentally, the pandemic has encouraged the application of e-learning techniques for the continuing professional development of medical doctors in the country. | 2021-02-08 |
| 33552457 | This study aims to evaluate COVID-19 treatment options using multicriteria decision-making (MCDM) techniques. […] In this study, we evaluated the available COVID-19 treatment options by MCDM techniques, namely, fuzzy PROMETHEE and VIKOR. […] These techniques are based on the evaluation and comparison of complex and multiple criteria to evaluate the most appropriate alternative. […] Fuzzy PROMETHEE and VIKOR techniques are applied in aiding decision-makers in choosing the right treatment technique for the management of COVID-19. | 2021-02-08 |
| 33552515 | We should achieve accurate diagnosis and treatment for cancer patients through advantages of multidisciplinary diagnosis and treatment team. | 2021-02-08 |
| 33552629 | Here we show that the diagnostic results are in excellent agreement with the findings of polymerase chain reaction-based optical methods; they also exhibit rapid detection speed (~10 min for nucleic acid detection and ~5 min for immunoassay). | 2021-02-08 |
| 33552746 | Real-Time Reverse-Transcription Polymerase Chain Reaction (RT-PCR) is currently the only recommended diagnostic method for SARS-CoV-2. | 2021-02-08 |
| 33552875 | This review has highlighted the different traditional therapeutic techniques, along with the potential contribution of nanomedicine against the severe acute respiratory syndrome corovirus-2 (SARS-CoV-2). […] The self-assembled and metallic nanovaccines mostly based on the antigenic properties of spike (S) protein are also approachable, feasible, and promising techniques for lowering the viral burden. […] There are number of NP-based diagnostic systems have been reported for coronaviruses (CoVs) and specifically for SARS-CoV-2. | 2021-02-08 |
| 33552895 | Despite being nonspecific, its diagnosis can be made by the association of clinical and imaging criteria. | 2021-02-08 |
| 33552932 | Proposed Fuzzy Cloud-Based (FCB) COVID-19 Diagnosis Assistant aims to identify the patients as confirmed, suspects, or suspicious of COVID-19. […] This database helps to improve diagnostic accuracy as it contains the latest updates from real-world cases data. | 2021-02-08 |
| 33553699 | Accomplishing these goals will require novel strategies that allow for diagnosis, data capture, and prediction of future IS risk using tools that are adaptable to the evolving clinical challenges in patient care delivery and research. | 2021-02-08 |
| 33553782 | Simple panel proposed by us with only two cytokine markers can be used as predictors for fast diagnosis of patients with higher risk of COVID-19 disease deterioration and thus can be managed well for a favourable prognosis. | 2021-02-08 |
| 33553808 | Identification of diagnostic biomarkers was conducted using receiver operating characteristic (ROC) curve analysis. […] In total, ten genes (CBL, ISG15, NEDD4, PML, REL, CTNNB1, ERBB2, JUN, RPS8 and STUB1) were identified as good diagnostic biomarkers. […] In conclusion, the identified DEGs, hub genes and target genes contribute to the understanding of the molecular mechanisms underlying the advancement of SARS-CoV-2 infection and they may be used as diagnostic and molecular targets for the treatment of patients with SARS-CoV-2 infection in the future. | 2021-02-08 |
| 33553890 | Here, we present a cost-effective smartphone-based device coupled with machine learning-driven software that evaluates the fluorescence signals of the CRISPR diagnostic of SARS-CoV-2. | 2021-02-08 |
| 33554040 | After adjusting for demographics, smoking status, and comorbidities, a diagnosis of cancer was independently associated with higher odds of hospitalization (odds ratio = 2.16, 95% confidence interval = 1.12 to 4.18) and 30-day mortality (odds ratio = 5.67, 95% confidence interval = 1.49 to 21.59). | 2021-02-08 |
| 33554045 | Advanced materials based on nanotechnology are the basis of several technologies starting from masks and personal protection equipment to specific diagnostic tools that could diminish the impact of COVID-19. | 2021-02-08 |
| 33554155 | We found that individuals with mild or asymptomatic infection experienced an insignificant decay in neutralizing activity, which persisted six months after symptom onset or diagnosis. | 2021-02-08 |
| 33554209 | Clinical, laboratory, and epidemiological criteria are the basis for this diagnosis. | 2021-02-08 |
| 33554436 | In 14%, diagnostic workup or hospitalisation was cancelled or postponed. | 2021-02-08 |
| 33554485 | At present, inadequate diagnosis and unreliable evaluation systems hinder the implementation and development of effective prevention and treatment strategies. […] We also detected anti-SARS-CoV-2 antibodies in the above clinical and animal model samples to identify a reliable approach for the accurate diagnosis of SARS-CoV-2 infection. […] Results showed that, regardless of clinical symptoms, the highest detection levels of viral nucleic acid were found in sputum and tracheal brush samples, resulting in a high and stable diagnosis rate. […] Furthermore, integration of nucleic acid detection results from the various sample types did not improve the diagnosis rate. […] Therefore, SARS-CoV-2 nucleic acid detection using lower respiratory tract samples alone is reliable for COVID-19 diagnosis and study. | 2021-02-08 |
| 33554490 | This situation can lead to delay in T1D diagnosis and insulin treatment resulting in rapid progression to diabetic ketoacidosis (DKA) and therefore increased risk of complications and death. . […] Regular education of the whole society about the symptoms of diabetes could contribute to faster diagnosis of T1D and reduction of DKA prevalence. . | 2021-02-08 |
| 33554506 | Diagnostic and screening sensitivity/specificity and positive/negative predictive value were calculated. […] Diagnostic sensitivity (ability to detect a COVID-19 positive patient) ≥14 days after positive PCR testing was 96.7% (95% CI 88.5-99.6%) for DiaSorin, 93.3% (95% CI 83.8-98.2%) for Roche and 100% (95% CI 94.0-100%) for Siemens. […] Lower diagnostic sensitivities were observed <14 days after onset of symptoms for all three assay. […] Diagnostic specificity (ability to detect a COVID-19 negative patient) was 95.0% (95% CI 89.4-98.1%) for DiaSorin, 99.2% (95% CI 95.4-99.9%) for Roche and 100% (95% CI 97.0-100%) for Siemens. | 2021-02-08 |
| 33554511 | However, mass community screening would require the use of more sensitive techniques. | 2021-02-08 |
| 33554523 | Although the most effective strategy for preventing or containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreaks relies on early diagnosis, the paramount and unprecedented number of tests needed to fully achieve this target is overwhelming worldwide testing supply and capacity. […] Molecular detection of SARS-CoV-2 RNA in nasopharyngeal swabs is still considered the reference diagnostic approach. […] However, these advantages are counterbalanced by lower diagnostic sensitivity compared to molecular testing, which would only enable to identifying patients with higher SARS-CoV-2 viral load. | 2021-02-08 |
| 33554557 | All tests showed very high diagnostic specificity. […] Thorough on-site evaluation of commercially available serologic tests for detection of antibodies against SARS-CoV-2 remains imperative for laboratories. | 2021-02-08 |
| 33554608 | Accurate and rapid testing for SARS-COV-2 antibodies could improve the diagnosis and management of COVID-19. […] In this study we aim to evaluate the diagnostic accuracy of a commercially available point of care lateral flow kit independently and in comparison to an established platform based system. | 2021-02-08 |
| 33554893 | The worst prognosis occurred most likely during the first month after COVID-19 diagnosis. | 2021-02-08 |
| 33555484 | Encephalitis caused by Herpes simplex type 1 is the most common cause of sporadic encephalitis, and early diagnosis and prompt treatment can prevent the devastating outcome. | 2021-02-08 |
| 33555535 | We analyzed the right ventricular functions of the patients using conventional techniques and two-dimensional speckle-tracking. | 2021-02-08 |
| 33555895 | Besides revealing the aspects of host-virus pathogenesis, our study opens new avenues to develop better diagnostic markers and therapeutic approaches. | 2021-02-08 |
| 33555956 | Hospitalized patients with a primary or secondary discharge diagnosis code for COVID-19 (ICD-10 code U07.1) from April 1 - October 31, 2020 were identified in the Premier Healthcare COVID-19 Database. | 2021-02-08 |
| 33556031 | In this scenario, clinicians may focus on documenting widely reported symptoms that appear to confirm the diagnosis of COVID-19, at the expense of infrequently reported symptoms. | 2021-02-08 |
| 33556034 | The Multinomial Logit Model (MNL) and Latent Class Model (LCM) were used to explore people’s preferences for different diagnosis methods. […] Among these respondents, 84.7% in 2017 and 91.3% in 2020 were confident that AI diagnosis would outperform human clinician diagnoses in the future. […] Both groups of respondents matched from 2017 and 2020 attached most importance to the attribute ‘accuracy’, and they prefer the combined diagnosis of AI and human clinicians (2017: odds ratio [OR] 1.645; 95% CI 1.535,1.763, p < 0.001; 2020: OR 1.513, 95% CI 1.413, 1.621, p < 0.001, Reference level: Clinician). […] In Class 1, the preference for combination diagnosis and accuracy remains constant in 2017 and 2020, and higher accuracy (e.g., 2017 OR for 100% 1.357; 95% CI 1.164, 1.581) is preferred. […] In Class 3, the respondents in 2017 and 2020 had different preferences for diagnosis method; respondents in Class 3 of 2017 prefer clinicians, whereas respondents in Class 3 of 2020 prefer AI diagnosis. […] Individual preference for clinical diagnosis between AI and human clinicians were mostly unaffected due to the pandemic. […] Diagnosis accuracy and expense for diagnosis were of the most important attributes of choice of the type of diagnosis. | 2021-02-08 |
| 33556041 | Inadequate diagnosis and poor health infrastructure jeopardize proper contact tracing and other actions to reduce the impact of COVID-19 in the region. | 2021-02-08 |
| 33556092 | It is further shown that the design could be produced using a variety of manufacturing methods, ranging from manual techniques to high-volume die-cutting and creasing. | 2021-02-08 |
| 33556151 | The COVID-19 pandemic challenged the resilience of public health, including diagnostic testing, antiviral development and transmission prevention. | 2021-02-08 |
| 33556355 | Three aspects are highlighted here: the first solution to assure quality and consistency to air sampling relies on the development of recovery tests using standard materials and investigating sampling materials, sampling techniques, sampling durations, sample conservation and pre-treatments; secondly, in order to overcome the shortcomings of every single sampling technique, coupling different samplers in parallel sampling could be an efficient strategy to collect more information and make data more reliable; finally, with regards to airborne virus sampling, the results could be confirmed by simplified emission and dilution models. | 2021-02-08 |
| 33556612 | This prospective study demonstrated that the LUMIPULSE antigen test is a highly accurate diagnostic for SARS-CoV-2. | 2021-02-08 |
| 33556700 | Eight parent-sibling dyads (16 individuals) completed semi-structured interviews discussing their family before, during and after receiving the ASD diagnosis, and in relation to the first UK lockdown. […] Dyads were, to an extent, consumed by the diagnosis both presently and in the future, implicating the need for a stretch in services to support parents and neurotypical siblings. | 2021-02-08 |
| 33556807 | This rapid pace in sensor development has been accentuated by vast improvements in data analysis methods in the form of machine learning and artificial intelligence that, together, promise fantastic opportunities in chronic sensing of biosignals to enable preventative screening, automated diagnosis, and tools for personalized treatment strategies. | 2021-02-08 |
| 33556918 | The aim of the present study was to evaluate the characteristics and outcomes of patients who were hospitalized with a diagnosis of COVID-19, who underwent psychiatric consultations. | 2021-02-08 |
| 33556920 | In the era of COVID-19 outbreak, various efforts are undertaken to develop a quick, easy, inexpensive, and accurate way for diagnosis. […] Although many commercial diagnostic kits are available, detailed scientific evaluation is lacking, making the public vulnerable to fear of false-positive results. […] Furthermore, our newly established risk assessment formula can be applied to a large-scale diagnosis in health institutions and agencies around the world. | 2021-02-08 |
| 33557013 | Post-viral fatigue syndrome (PVFS) is a widespread chronic neurological disease with no definite etiological factor(s), no actual diagnostic test, and no approved pharmacological treatment, therapy, or cure. | 2021-02-09 |
| 33557213 | Monitoring acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genetic diversity and emerging mutations in this ongoing pandemic is crucial for understanding its evolution and assuring the performance of diagnostic tests, vaccines, and therapies against coronavirus disease (COVID-19). | 2021-02-09 |
| 33557418 | Compared with this, the most sensitive EIAs were the Cobas Elecsys Anti-SARS-CoV-2 (98%) and Vitros Immunodiagnostic Anti-SARS-CoV-2 (100%), which detect total antibody targeting the N and S1 antigens, respectively. | 2021-02-09 |
| 33557431 | Pseudothrombocytopenia (PTCP), a relative common finding in clinical laboratories, can lead to diagnostic errors, overtreatment, and further (even invasive) unnecessary testing. […] New analytical technologies, such as fluorescence or optical platelet counting, will be soon overturning traditional algorithms and represent valuable diagnostic aids. | 2021-02-09 |
| 33557662 | Countries with higher International Health Regulations score were significantly more likely to have lower incidence (β coefficient -24, 95% CI -35 to -13) and mortality (β coefficient -1.7, 95% CI -2.5 to -1.0) per 100,000 population within 30 days since the first COVID-19 diagnosis. | 2021-02-09 |
| 33557772 | Currently, there is an urgent need for efficient tools to assess the diagnosis of COVID-19 patients. […] Two structurally-different deep learning techniques, SegNet and U-NET, are investigated for semantically segmenting infected tissue regions in CT lung images. […] Semantically segmenting CT scan images of COVID-19 patients is a crucial goal because it would not only assist in disease diagnosis, also help in quantifying the severity of the illness, and hence, prioritize the population treatment accordingly. […] We propose computer-based techniques that prove to be reliable as detectors for infected tissue in lung CT scans. | 2021-02-09 |
| 33557873 | We propose a diagnostic algorithm, to help case definition and guide work-up, and a therapeutic approach. | 2021-02-09 |
| 33557906 | Pediatricians are confronted with COVID-19 in a variety of presentations, which may lead to delayed diagnosis and treatment. […] Early diagnosis of the disease plays an important role in preventing transmission of the virus in the community. | 2021-02-09 |
| 33557927 | The aim of RApid community Point-of-care Testing fOR COVID-19 (RAPTOR-C19) is to assess the diagnostic accuracy of multiple current and emerging point-of-care tests (POCTs) for active and past SARS-CoV2 infection in the community setting. […] RAPTOR-C19 will provide the community testbed to the COVID-19 National DiagnOstic Research and Evaluation Platform (CONDOR). […] RAPTOR-C19 incorporates a series of prospective observational parallel diagnostic accuracy studies of SARS-CoV2 POCTs against laboratory and composite reference standards in patients with suspected current or past SARS-CoV2 infection attending community settings. […] In contrast, poorly performing POCTs could have negative effects, so it is necessary to undertake community-based diagnostic accuracy evaluations before rolling these out. | 2021-02-09 |
| 33558024 | In this review we compare the clinical features, diagnosis, and pathogenesis of COVID-CSS with other hematological CSS, namely secondary hemophagocytic lymphohistiocytosis (sHLH), idiopathic multicentric Castleman disease (iMCD), and CAR-T cell therapy associated Cytokine Release Syndrome (CRS). […] Established markers of inflammation as well as cytokine levels are compared and contrasted between these four entities in order to establish a foundation for future diagnostic criteria of COVID-CSS. | NA |
| 33558047 | In order to deal with the current pandemic caused by the novel SARS-CoV-2 coronavirus several serological immunoassays have been recently developed with the objective of being used as a complementary diagnostic tool and to support the RT-PCR technique currently considered the “gold-standard” method. […] In addition, we observed very good agreements among them, being better for the detection of IgG than for IgM antibodies (Cohen’s kappa index of 0.95 for VIRCLIA® IgG with ROCHE®), as well as good diagnostic power of the tests as determined by the ROC curves. […] This study demonstrates the proper performance of the different immunoassays in order to be applied in the clinical practice as support in the diagnostic approach and in the development of vaccines and seroepidemiological studies of COVID-19. | 2021-02-09 |
| 33558139 | Particularly in patients with cancer, these changes can exacerbate the pre-existing psychological stress associated with cancer diagnosis and treatment. […] Physicians treating these patients need to be aware of the psychologic stress the combined effects of the COVID-19 pandemic, cancer diagnosis, and cancer treatment can have and make appropriate referrals to support the holistic care of their patients. | 2021-02-09 |
| 33558330 | Community-acquired pneumonia (CAP) is an essential consideration in patients presenting to primary care with respiratory symptoms; however, accurate diagnosis is difficult when clinical and radiological examinations are not possible, such as during telehealth consultations. […] Five cough audio-segments were recorded and four patient-reported symptoms (fever, acute cough, productive cough, and age) were analysed by the smartphone-based algorithm to generate an immediate diagnostic output for CAP. […] Diagnostic agreement was calculated against the confirmed discharge diagnosis of CAP by specialist physicians. […] The algorithm provides rapid and accurate diagnosis of CAP. | 2021-02-09 |
| 33558358 | In Italy, the first diagnosis of COVID-19 was confirmed on 20 February 2020 in the Lombardy region. […] In this paper, we aim to evaluate the hypothesis on the early presence of the virus in Italy by analysing data on trends of access to emergency departments (EDs) of subjects with a diagnosis of pneumonia during the 2015-2020 period. | 2021-02-09 |
| 33558602 | We followed a total of 1040 patients with a positive RT-PCR diagnosis for COVID-19 from a large hospital from São Paulo, Brazil, from March to June 2020, of which 288 (28%) presented a severe prognosis, i.e. | 2021-02-09 |
| 33558607 | We first develop unsupervised modelling techniques based on associated symptom categories identified by the United Kingdom’s National Health Service and Public Health England. […] We also investigate transfer learning techniques for mapping supervised models from countries where the spread of the disease has progressed extensively to countries that are in earlier phases of their respective epidemic curves. | 2021-02-09 |
| 33558635 | Effective diagnosis, treatment, and prophylactic measures are urgently required to meet global demand: recombinant antibodies fulfill these requirements and have marked clinical potential. | 2021-02-09 |
| 33558710 | Early diagnosis of cancer, followed by timely and appropriate therapy, are the cornerstones of the secondary prevention of cancer, thus the NHS has set a 2028 target to achieve 75% early stage (TNM I/II) at cancer diagnosis. […] In this context, Barclay et al. evaluated overall, sex, age and deprivation-group-specific progress towards this target based on 202,000 cancer patients diagnosis in 2015. […] We discuss the impact of the pandemic and the efforts being made in innovative early detection and diagnosis research. | 2021-02-09 |
| 33558826 | Early diagnosis of suspected patients will play an essential role in preventing further spread of COVID-19. […] With the results revealing no significant difference between the two types of specimen in the diagnosis of COVID-19, the use of saliva specimen is preferable for widespread use because it is easily collected without the need for qualified health workers. […] However, more in vivo studies are required in order to compare and evaluate saliva and NPS specimens in detecting COVID-19 using various techniques. | 2021-02-09 |
| 33558835 | Sixty-two consecutive adult HD patients with confirmed COVID-19 from four dialysis facilities in Paris, France, from 19 March to 19 May 2020 were included.Blood tests were performed before diagnosis and at Days 7 and 14 after diagnosis. […] Compared with non-severe forms, these patients had more fever (93% versus 56%, P < 0.01), cough (71% versus 38%, P = 0.02) and dyspnoea (43% versus 6%, P < 0.01) at diagnosis. […] At Day 7 post-diagnosis, neutrophil counts, neutrophil:lymphocyte (N:L) ratio, C-reactive protein, ferritin, fibrinogen and lactate dehydrogenase levels were significantly higher in severe COVID-19 patients. | 2021-02-09 |
| 33558866 | Conclusions Our findings indicate negative mental health effects of the global COVID-19 pandemic and the restrictive measures in a particularly vulnerable population, with differential effects on diagnostic groups. | 2021-02-09 |
| 33559334 | The current study suggests that autistic adults who were younger, female, had a mental health diagnosis before the pandemic and knew someone who showed symptoms or tested positive for COVID-19 reported more areas negatively impacted by COVID-19 and greater difficulty coping with those effects. | 2021-02-09 |
| 33559558 | There were 824 orthopaedic referrals and 358 admissions (six/day) in the non-COVID period, with 38/358 (10.6%) admissions having a psychiatric diagnosis and 30/358 (8.4%) also having a fracture. […] This was compared with 473 referrals and 195 admissions (three/day) in the COVID period, with 73/195 (37.4%) admissions having a documented psychiatric diagnosis and 47/195 (24.1%) having a fracture. […] There was a reduction in the number of admissions and referrals during the pandemic, but a simultaneous three-fold rise in admissions with a psychiatric diagnosis. […] The proportion of patients with both a fracture and a psychiatric diagnosis more than doubled and the number of patients presenting due to a traumatic suicide attempt almost tripled. | 2021-02-09 |
| 33559755 | After the diagnosis of a giant cell arteritis, treatment with an oral glucocorticoid and subcutaneous methotrexate (MTX) was initiated, with good clinical and laboratory parameter responses. | 2021-02-09 |
| 33559789 | ROC curve cutoff values pointed that VAS > 70 severity, > 9 h duration, > 5 headache days, and IL-6 > 43 pg/mL levels can be diagnostic for COVID-19 headache. | 2021-02-09 |
| 33560178 | As a mitigation strategy, we ask that readers refocus on the fundamental principal of diagnostic testing: pretest probability. | 2021-02-09 |
| 33560192 | Interobserver agreement for categories with findings typical of COVID-19 and those suggesting an alternative diagnosis is high across multiple studies. […] Finally, artificial intelligence has shown promise in both diagnosis and prognosis of COVID-19 pneumonia both with respect to radiography and CT. | 2021-02-09 |
| 33560208 | Electronic medical records were queried for sleep disorders diagnostic codes. […] Data was extracted from polysomnography and home sleep testing in a subgroup with previous diagnostic testing at our center. | 2021-02-09 |
| 33560451 | The pandemic situation may make difficult to prioritize patients with allergies diseases (AD), face-to-face evaluation, and moreover concern about the possible COVID-19 diagnosis, since COVID-19 shared many symptoms in common with AD. | 2021-02-09 |
| 33560453 | The diagnosis of interstitial pneumonia was done considering lung alterations of CT of PET. | 2021-02-09 |
| 33560511 | Concentration techniques were recognized as useful to offset such negative outcomes. | 2021-02-09 |
| 33560555 | All patients with a diagnosis of inflammatory bowel disease, aged <18 years, and under the care of Southampton Children’s Hospital were eligible for inclusion. | 2021-02-09 |
| 33560673 | To summarize current literature evidence on the role of computed tomography (CT) scan in the diagnosis and assessment of coronavirus disease 2019 (COVID-19) pneumonia. […] Since COVID-19 was declared as a global pandemic, there was a push towards identifying appropriate diagnostic tests that are both reliable and effective. | 2021-02-09 |
| 33560995 | Automated lung infections classification using chest X-ray (CXR) images could strengthen diagnostic capability when handling COVID-19. | 2021-02-09 |
| 33560998 | Here, we provide an overview of recently published literature on the COVID-19 pandemics in four strategic areas: (1) triage, diagnosis and risk prediction; (2) drug repurposing and development; (3) pharmacogenomics and vaccines; (4) mining of medical literature. | 2021-02-09 |
| 33561010 | Circulating SARS-CoV-2 RNA may represent a more reliable indicator of infection than nasal RNA, but RT-qPCR lacks diagnostic sensitivity for blood samples. […] A CRISPR-augmented RT-PCR assay that sensitively detects SARS-CoV-2 RNA was employed to analyze viral RNA kinetics in longitudinal plasma samples from nonhuman primates (NHP) after virus exposure; to evaluate the utility of blood SARS-CoV-2 RNA detection for COVID-19 diagnosis in adults cases confirmed by nasal/nasopharyngeal swab RT-PCR results; and to identify suspected COVID-19 cases in pediatric and at-risk adult populations with negative nasal swab RT-qPCR results. […] In a patient cohort (n=159), this blood-based assay demonstrated 91.2% diagnostic sensitivity and 99.2% diagnostic specificity versus a comparator RT-qPCR nasal/nasopharyngeal test, while RT-qPCR exhibited 44.1% diagnostic sensitivity and 100% specificity for the same blood samples. […] Results of this study indicate that sensitive detection of SARS-CoV-2 RNA in blood by CRISPR-augmented RT-PCR permits accurate COVID-19 diagnosis, and can detect COVID-19 cases with transient or negative nasal swab RT-qPCR results, suggesting that this approach could improve COVID-19 diagnosis and the evaluation of SARS-CoV-2 infection clearance, and predict the severity of infection. | 2021-02-09 |
| 33561159 | Although antiretroviral therapy (ART) has been able to decrease the mortality rate of these diseases, particularly cryptococcosis, the disproportionately low distribution of funds to their diagnosis and treatment remains an obstacle in saving and improving the lives of patients affected. […] Due to progressive symptoms and high mortality rates of COVID-19 compared to fungal infections, particularly the FNTDs, funding is currently allocated predominantly for diagnostic and therapeutic research on COVID-19. | 2021-02-09 |
| 33561190 | TNP scores of cognitively normal (CN) patients were compared with patients with neurocognitive disorders (NCD), and score profiles were examined among suspected diagnostic groups of Alzheimer’s disease (AD), Parkinson’s disease (PD), and vascular disease (VaD). | 2021-02-09 |
| 33561453 | As more novel viruses with pandemic potential are expected to arise in future, these techniques are not limited to application to SARS-CoV-2 but also useful to rapidly respond to novel emerging viruses. | 2021-02-09 |
| 33561624 | Finally, we suggest the diagnostic/prognostic purpose of the elevated lactate levels that can be determined through sweat lactate testing. | 2021-02-09 |
| 33562011 | The aim of this study was to determine on chest computed tomography (CT) images whether a deep convolutional neural network algorithm is able to solve the challenge of differential diagnosis between COVID-19 pneumonia and ICI therapy-related pneumonitis. | 2021-02-10 |
| 33562309 | Computed tomography (CT) is an informative tool for the diagnosis of COVID-19 patients. […] However, due to the high complexity and non-transparency of deep models, the explanation of the diagnosis process is challenging, making it hard to evaluate whether such approaches are reliable. […] In this paper, we propose a visual interpretation architecture for the explanation of the deep learning models and apply the architecture in COVID-19 diagnosis. […] Our architecture designs a comprehensive interpretation about the deep model from different perspectives, including the training trends, diagnostic performance, learned features, feature extractors, the hidden layers, the support regions for diagnostic decision, and etc. […] With the interpretation architecture, researchers can make a comparison and explanation about the classification performance, gain insight into what the deep model learned from images, and obtain the supports for diagnostic decisions. […] Our deep model achieves the diagnostic result of 94.75%, 93.22%, 96.69%, 97.27%, and 91.88% in the criteria of accuracy, sensitivity, specificity, positive predictive value, and negative predictive value, which are 8.30%, 4.32%, 13.33%, 10.25%, and 6.19% higher than that of the compared traditional methods. […] It can also help deep learning methods to take a step forward in the clinical COVID-19 diagnosis field. | 2021-02-10 |
| 33562419 | The global spread of severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), could be due to limited access to diagnostic tests and equipment. […] Here, we tested MWR use first time for the early diagnosis of pulmonary COVID-19 complications in a cross-sectional controlled trial in order to evaluate MWR use in hospitalized patients with COVID-19 pneumonia and healthy individuals. | 2021-02-10 |
| 33562759 | Since myocarditis continues to be a significant public health issue, particularly in young adults in whom myocarditis is among the most common causes of sudden cardiac death, improved diagnostic and therapeutic procedures are necessary. […] This manuscript aims to summarize the current knowledge on the epidemiology of myocarditis, new diagnostic approaches and the current epidemiological impact of the COVID-19 pandemic. | 2021-02-10 |
| 33563186 | One of the major solutions seems to be early detection of the carriers, particularly the asymptomatic people with the help of sensitive and accurate diagnostic techniques. […] In this review, we discuss new therapeutic outcomes and cover and the most significant aspects of COVID-19, including the epidemiology, biological features, organs failure, and diagnostic techniques. | 2021-02-10 |
| 33563325 | Patients hospitalized on dedicated COVID wards are eligible for study inclusion when they are symptomatic (i.e., clinical or radiological signs) and have been diagnosed with COVID-19 within the last 72 h through PCR (nasopharyngeal swab or bronchoalveolar lavage) or chest CT scan showing typical features of COVID-19 and without alternate diagnosis. | 2021-02-10 |
| 33563624 | Adults with CDs were categorised based on a self-reported diagnosis of diabetes, high blood pressure, heart disease/heart attack/stroke, asthma, chronic obstructive pulmonary disease (COPD), bronchitis or emphysema, cystic fibrosis, liver disease, compromised immune system, or cancer (54%). -p=0.001). | 2021-02-10 |
| 33563629 | To describe the characteristics and outcomes of patients with a clinical diagnosis of COVID-19 and false-negative SARS-CoV-2 reverse transcription-PCR (RT-PCR), and develop and internally validate a diagnostic risk score to predict risk of COVID-19 (including RT-PCR-negative COVID-19) among medical admissions. […] Main outcomes were diagnosis of COVID-19, SARS-CoV-2 RT-PCR results, sensitivity of SARS-CoV-2 RT-PCR and mortality during hospital admission. […] For the diagnostic risk score, we report discrimination, calibration and diagnostic accuracy of the model and simplified risk score and internal validation. 4008 patients were admitted between 2 March and 3 May 2020. 1792 patients (44.8%) were diagnosed with COVID-19, of whom 1391 were SARS-CoV-2 RT-PCR positive and 283 had only negative RT-PCRs. […] A simple diagnostic risk score comprising of age, sex, ethnicity, cough, fever or shortness of breath, National Early Warning Score 2, C reactive protein and chest radiograph appearance had moderate discrimination (area under the receiver-operator curve 0.83, 95% CI 0.82 to 0.85), good calibration and was internally validated. […] Diagnostic risk scores could potentially help triage patients requiring admission but need external validation. | 2021-02-10 |
| 33563823 | Here, we report that repeated milk samples collected from 18 women following COVID-19 diagnosis did not contain SARS-CoV-2 RNA; however, risk of transmission via breast skin should be further evaluated. | 2021-02-10 |
| 33563901 | Interestingly, at COVID-19 diagnosis, MPN patients had significantly lower platelet count (p < 0.0001) than in the pre-COVID last follow-up.This decline was remarkably higher in ET (-23.3%, p < 0.0001) than in PV (-16.4%, p = 0.1730) and was associated with higher mortality rate (p = 0.0010) for pneumonia. | 2021-02-10 |
| 33563967 | A lot of serological diagnostic kits have been proposed on the market but validation studies have not been published for many of them. | NA |
| 33564223 | This imposes a pressing need for the development of anti-viral therapeutic agents and diagnostic tools that demonstrate multifunctional, target-specific, and non-toxic properties. […] Nanotheranostics facilitates targeted drug-delivery of anti-viral therapeutics as well as contributing to the development of diagnostic systems. […] Multifunctional metallic nanoparticles (NPs) have emerged as innovative theranostic agents that enable sustainable treatment and effective diagnosis. […] Metal-based NPs could act as carriers that enable the sustainable and targeted delivery of active anti-viral molecules, or as diagnostic agents that allow rapid and sensitive diagnosis of viral infections. | 2021-02-10 |
| 33564287 | In this case, only by adhering to the prevention and control methods of early diagnosis, early isolation, and early treatment, can the spread of the virus be prevented to the greatest extent. […] This article uses artificial intelligence-assisted medical imaging diagnosis as the research object, combines artificial intelligence and CT medical imaging diagnosis, introduces an intelligent COVID-19 detection system, and uses it to achieve COVID-19 disease screening and lesion evaluation. […] CT examination has the advantages of fast speed and high accuracy, which can provide a favorable basis for clinical diagnosis. […] Two professional radiologists analyzed the CT images using traditional imaging diagnostic methods and artificial intelligence-assisted imaging diagnostic methods, and the comparison showed the gap between the two methods. […] According to experiments, CT imaging diagnosis assisted by artificial intelligence only takes 0.744 min on average, which can save a lot of time and cost compared with the average time of 3.623 min for conventional diagnosis. […] In terms of comprehensive test accuracy, it can be concluded that the combination of artificial intelligence and imaging diagnosis has extremely high application value in COVID-19 diagnosis. | 2021-02-10 |
| 33564315 | It is carried out with the help of multivariate statistics techniques. | 2021-02-10 |
| 33564397 | diagnostic tests and their performance" of 15 April 2020 and is freely accessible at https://covid-19-diagnostics.jrc.ec.europa.eu/. | 2021-02-10 |
| 33564500 | We present a rare case of a 46-year-old woman with SSc with new onset of renal failure after a recent diagnosis of COVID-19. | 2021-02-10 |
| 33564509 | Here, we present a case series of five patients who were either asymptomatic or had very mild symptoms of COVID-19 infection upon diagnosis. […] These patients neither required a visit to the emergency department (ED) nor did they need to be hospitalized but became symptomatic and were found to have interstitial lung disease four to eight weeks after a COVID-19 diagnosis. | 2021-02-10 |
| 33564538 | Methods A retrospective cohort study involving 25 patients with a confirmed diagnosis of non-severe COVID-19 infection was conducted. | 2021-02-10 |
| 33564744 | These data, as well as mortality and further laboratory parameters, were compared across groups based on COVID-19 diagnosis and severity of disease. | 2021-02-10 |
| 33564833 | We describe the development, implementation, and outcomes of an inpatient diagnostic algorithm and clinical decision support system (CDSS) to evaluate PUIs. […] We conducted a pre-post study of CORAL (COvid Risk cALculator), a CDSS that guides frontline clinicians through a risk-stratified COVID-19 diagnostic workup, removes transmission-based precautions when workup is complete and negative, and triages complex cases to Infectious Diseases (ID) physician review. […] CORAL is an efficient and effective CDSS to guide frontline clinicians through the diagnostic evaluation of PUIs and safe discontinuation of precautions. | 2021-02-10 |
| 33564990 | In the month of January 2020, the whole genome of SARS-CoV2 was sequenced which made work easy for researchers to develop diagnostic kits and to carry out drug repurposing to effectively alleviate the pandemic situation in the world. | 2021-02-10 |
| 33565000 | To analyze diagnostic accuracy of chest computed tomography (CT) and RT-PCR (real-time polymerase chain reaction) for COVID-19 (coronavirus disease 19) pneumonia in early and progressive stages. […] To evaluate if combination of chest CT with RT-PCR can supplement the shortage of RT-PCR in diagnosis of COVID-19 pneumonia. | 2021-02-10 |
| 33565027 | In comparison, the chest CT has been considered as the prior choice in diagnosis and monitoring progress of COVID-19 infection. […] Although the COVID-19 diagnostic systems based on artificial intelligence have been developed for assisting doctors in diagnosis, the small sample size and the excessive time consumption limit their applications. […] To this end, this paper proposed a diagnosis prototype system for COVID-19 infection testing. […] Highly compressed image like Jpeg can be used to allow a quick diagnosis; and (3) it discriminates the virus infection within 6 seconds and thus allows an online test with light cost. | 2021-02-10 |
| 33565225 | Since the beginning of the COVID-19 epidemic, a large number of guidelines on diagnosis and treatment of COVID-19 have been developed, but the quality of those guidelines and the consistency of recommendations are unclear. […] The objective of this study is to evaluate the quality of the diagnosis and treatment guidelines on COVID-19 and analyze the consistency of the recommendations of these guidelines. […] We searched for guidelines on diagnosis and/or treatment of COVID-19 through PubMed, CBM, CNKI, and WanFang Data, from January 1, 2020 to August 31, 2020. […] We included diagnosis and/or treatment guidelines for COVID-19, including rapid advice guidelines and interim guidelines. […] We described the consistency of the direction of recommendations for treatment and diagnosis of COVID-19 across the included guidelines. […] The recommendations on diagnosis and treatment were to some extent consistent between the included guidelines. […] Computed tomography (CT), X-rays, lung ultrasound, RT-PCR, and routine blood tests were the most commonly recommended methods for COVID-19 diagnosis. […] The methodological quality of currently available diagnosis and treatment guidelines for COVID-19 is low. […] The diagnosis and treatment recommendations between the included guidelines are highly consistent. […] The main diagnostic methods for COVID-19 are RT-PCR and CT, with ultrasound as a potential diagnostic tool. | 2021-02-10 |
| 33565568 | A symptom-score ≥5, calculated on 195 patients with RT-PCR COVID-19 disease (sensitivity/specificity of 0.815/0.780 respectively) was used for the diagnosis. | 2021-02-10 |
| 33566110 | Confirmed cases were defined as COVID-19 infection confirmed by a diagnostic laboratory test. | 2021-02-10 |
| 33566573 | Herein, we introduce the MagiCoil diagnostic device, an inexpensive, portable, quantitative, and rapid bioassay platform based on the magnetic particle spectrometer (MPS) technique. | 2021-02-10 |
| 33566704 | We recommend that all physicians consider COVID-19 as a differential diagnosis in the presence of acute conjunctivitis with or without systemic symptoms. | 2021-02-10 |
| 33566791 | Advice using behavior change techniques in Germ Defence led to intentions to improve these behaviors. | 2021-02-10 |
| 33566873 | Widespread diagnostic testing is needed to reduce transmission of COVID-19 and manage the pandemic. […] Detection of SARS-CoV-2 RNA using AG processing with direct RT-qPCR provides a reliable and scalable diagnostic test for COVID-19 that can be integrated into a range of workflows, including automated settings. | 2021-02-10 |
| 33566921 | Diverse clinical characteristics should be considered for early diagnosis of COVID-19 in children. | 2021-02-10 |
| 33566990 | The lack of mass testing for COVID-19 diagnosis creates the need to determine the magnitude of the disease based on its clinical symptoms. | 2021-02-10 |
| 33567163 | Decreased cancer incidence and reported changes to clinical management indicate that the COVID-19 pandemic has delayed cancer diagnosis and treatment. […] This study aimed to develop and apply a flexible model to estimate the impact of delayed diagnosis and treatment on survival outcomes and healthcare costs based on a shift in the disease stage at treatment initiation. | 2021-02-10 |
| 33567626 | A prompt diagnosis of SARS-CoV-2 infection is crucial for the timely adoption of isolation measures and the appropriate management of cancer treatments. […] In lung cancer patients the symptoms of infection 19 may resemble those exhibited by the underlying oncologic condition, possibly leading to diagnostic overlap and delays. | 2021-02-11 |
| 33567748 | As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this disease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients with other conditions admitted to ICU. | 2021-02-11 |
| 33568153 | Autopsy of deceased patients fulfilling diagnostic criteria for DIC revealed microthromboses in multiple organs. | 2021-02-11 |
| 33568424 | /L and relative monocytosis (>9%) were common among patients with a confirmed COVID-19 diagnosis. | 2021-02-11 |
| 33568541 | The CO-MY-COVID registry was a multicenter, retrospective, observational cohort study conducted in neuromuscular referral centers and general hospitals of the FILNEMUS network (between March 1, 2020, and June 8, 2020), including MG patients with a confirmed or highly-suspected diagnosis of COVID-19. | 2021-02-11 |
| 33568956 | Since earlier times, the diagnosis has been an important procedure in estimating the fate of epidemics by indicating the extent to which disease has been spread and to the extent, further disease prognosis would occur. […] The absence of anti-viral therapies and vaccines for COVID-19 at present suggests early diagnosis and isolation of the patients as the only smart approach available as of now. […] Presently, the increasing death rates, faster rates of transmission, non-availability of vaccines, and treatment have over-pressurized the researchers, health professionals, and government officials to develop effective clinical strategies in diagnosis and to come up with guidelines to be followed during conduction of each diagnostic procedure for maintaining healthcare systems. […] Therefore, early diagnosis and isolation of susceptible individuals are the only way to limit the spread of the virus. […] Significance of diagnosis and triaging, information on specimen collection, safety considerations while handling, transport, and storage of samples have been highlighted in this paper to make people more aware and develop better clinical strategies in the future. | 2021-02-11 |
| 33569033 | However, rates of hospitalization and diagnosis by neuroimaging remained stable across the study period. | 2021-02-11 |
| 33569177 | Widespread diagnostic and serological (antibody) testing is one key to mitigating the COVID-19 pandemic. […] While at first, the majority of COVID-19 diagnostic testing in the USA took place in healthcare settings, quickly a direct-to-consumer (DTC) testing market also emerged. […] The first part of this paper provides an overview of the landscape of diagnostic and serological tests for COVID-19, anticipating how provision models are likely to evolve in the future. | 2021-02-11 |
| 33569392 | Experimental and computational techniques involved will be emphasized. | 2021-02-11 |
| 33569402 | This study included 59 patients (32 newly admitted and 27 hospitalized for ≥2 weeks) with a COVID-19-confirmed diagnosis at the Shanghai Public Health Clinical Center from March 3, 2020, to March 21, 2020. | 2021-02-11 |
| 33569413 | Our study has potentially provided an accurate tool on chest CT for early diagnosis of NCP with high transferability and showed high efficiency in differentiating between NCP and IP; these findings could help to reduce misdiagnosis and contain the pandemic transmission. | 2021-02-11 |
| 33569465 | Here, we summarized the clinical features, diagnosis, treatment, and prognosis of COVID-19 patients based on our clinical practice. | 2021-02-11 |
| 33569794 | We conducted a study to examine the impact of COVID on patients’ access and utilization of prenatal genetic screens and diagnostic tests at the onset of the COVID-19 pandemic in the U.S. […] We conducted telephone interviews with 40 patients to examine how the pandemic affected prenatal genetic screening and diagnostic testing decisions during the initial months of the pandemic in the U.S. | 2021-02-11 |
| 33569817 | The versatile clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system has emerged as a promising technology for therapy and molecular diagnosis. […] It is especially suited for overcoming viral infections outbreaks, since their effective control relies on an efficient treatment, but also on a fast diagnosis to prevent disease dissemination. […] Here, we thoroughly review recent advances in the use of the CRISPR/Cas system for the treatment and diagnosis of viral deleterious infections such as HIV or SARS-CoV-2, examining their strengths and limitations. | 2021-02-11 |
| 33570039 | By reflecting various physiopathological mechanisms, these biomarkers allow both a better understanding of the pathophysiology of Covid-19 and a contribution to the diagnosis of neurologic troubles; they could participate in the prognostic evaluation of patients. | 2021-02-11 |
| 33570199 | Two of the patients with hyperfiltration exhibited high blood pressure levels at diagnosis, and persistence of prehypertension at 6-month follow-up. | 2021-02-11 |
| 33570399 | The control of viral outbreaks requires a nucleic acid diagnostic test that is sensitive and simple and delivers fast and reliable results. […] The entire contiguous sample-to-answer workflow takes less than 40 min from a clinical swab sample to a diagnostic result without professional instruments and technicians. | 2021-02-11 |
| 33570430 | These data may suggest that some ED referral usually could be deferred, but on the other hand, pandemic will cause a great diagnostic delay. | 2021-02-11 |
| 33570576 | Eight of these positive samples were detected by the CRISPR-based assay and confirmed by Clinical Laboratory Improvement Amendments-certified diagnostic testing. | 2021-02-11 |
| 33570755 | Cases with a confirmed COVID-19 diagnosis or closed as “undetermined etiology” were deemed eligible. | 2021-02-11 |
| 33570775 | A 4-day old, 3.3 kg infant presented with suspected intestinal malrotation, necessitating emergent diagnostic laparoscopy. | 2021-02-11 |
| 33571095 | Extracted features are then processed by different machine learning and statistical modeling techniques to identify COVID-19 cases. | 2021-02-11 |
| 33571280 | This retrospective assessment was designed to quantify the correlation between pre-diagnosis aspirin and mortality for COVID-19 positive patients in our care. […] Findings demonstrated that pre-diagnosis aspirin prescription was strongly associated with decreased mortality rates for Veterans diagnosed with COVID-19. | 2021-02-11 |
| 33571300 | Data were extracted from the COVID-19 database of the Integrated Argentina Health Information System, encompassing the period of March 3rd to October 2nd, 2020, using a standardized case report form that included information on contact history, clinical signs and symptoms, and clinical diagnosis. | 2021-02-11 |
| 33571742 | The efforts were mainly aimed to acquire epidemiological, microbiological, pathogenetic, clinical, diagnostic, therapeutic and preventive information in order to increase the available weapons to fight an infection which was rapidly taking on the characteristics of the pandemic. | 2021-02-11 |
| 33571800 | Demographic data collected include age, race, gender, ethnicity, diagnosis, and admission status (one or multiple admissions). | 2021-02-11 |
| 33571860 | SARS-CoV-2 pandemic shows the importance of having efficient virus diagnosis, especially in groups of particular relevance such as health care professionals, without involving a large economic expense. […] Pools of 10 samples were performed, using the Xpert® Xpress SARS-CoV-2 test for the diagnosis from clinical samples of nasopharyngeal exudate. […] It can be concluded that the described sample pooling system is a useful and efficient tool in the diagnosis of SARS-CoV-2 in certain groups, assuming a cost reduction without reducing the sensitivity. | 2021-02-11 |
| 33571889 | Temporary changes to the diagnostic testing for GDM have been recommended for the COVID-19 pandemic. | 2021-02-11 |
| 33571900 | Lack of physical contact when working through telehealth was perceived to hamper accurate and effective diagnosis and management. | 2021-02-11 |
| 33572570 | The threshold for evaluation or diagnosis of thromboembolism should be low given the high frequency of these events. | 2021-02-12 |
| 33572857 | To this end, current up-to-date information on the coronavirus evolution and SARS-CoV-2 modes of transmission, detection techniques and current control and prevention strategies are summarized in this review. | 2021-02-12 |
| 33573631 | Psychoeducational interventions mainly included cognitive-behavioural techniques, stress management techniques, mindfulness-based stress reduction and positive psychotherapy. […] The present results could help mental health professionals to determine which psychological techniques should be emphasized to promote patients’ resilience in the context of COVID-19 disease. | 2021-02-12 |
| 33573650 | Furthermore, the economic burden of the disease in the country for inpatient cases with the definitive diagnosis was 22,688,925,933,095 Rials equal to $ 1,439,083,784. | 2021-02-12 |
| 33573681 | For the Covid-19 subgroup, the SARS-CoV2 infection is proved by RT-PCR <7 days before admission and/or another approved diagnostic technique and/or typical CT appearance pneumonia. | 2021-02-12 |
| 33573780 | To analyze COVID-19 mortality in cancer patients and associated factors such as age, sex, type of insurance, situation at COVID-19 diagnosis, and cancer histology during the pandemic at a cancer center in Brazil. […] There were no statistical differences in survival by sex, age group, type of insurance, situation at the diagnosis of COVID-19, and histology of cancer for COVID-19. | 2021-02-12 |
| 33573853 | We described a case report of a 50 years-old-woman admitted to the emergency department with abdominal pain associated with febrile hepatosplenomegaly with the final diagnosis of suprahepatic vein thrombosis secondary to COVID-19. | 2021-02-12 |
| 33574010 | Twenty five patients received plasma therapy within 7 days (early) of diagnosis of Covid-19 infection. […] Median day of plasma infusion from date of diagnosis of Covid-19 infection was 4 days (range: 2-25 days). | 2021-02-12 |
| 33574054 | The diagnostic work-up was consistent with ICIs-related pneumonia and it is conceivable that lung injury by SARS-CoV-2 has acted as an inflammatory primer for the development of the immune-related adverse event.Patients recovered from COVID-19 starting ICIs could be at greater risk of recall immune-mediated pneumonitis. […] The awareness of the phenomenon could allow an easier interpretation of radiological changes under treatment and a faster diagnostic work-up to resume ICIs. | 2021-02-12 |
| 33574070 | for the management of patients referred to respiratory triage during the early stages of the SARS-CoV-2 pandemic, either chest radiograph (CXR) or computed tomography (CT) were used as first-line diagnostic tools. […] The aim of this study was to compare the impact on triage, diagnosis and prognosis of patients with suspected COVID-19 when clinical decisions are derived from reconstructed CXR or from CT. we reconstructed CXR (r-CXR) from high-resolution CT (HRCT) scan. | 2021-02-12 |
| 33574116 | Multiparametric algorithms showed variable diagnostic performances in predicting survival, hospitalisation, disease progression or severity, and mortality. | 2021-02-12 |
| 33574119 | Serological SARS-CoV-2 assays are needed to support clinical diagnosis and epidemiological investigations. […] Recently, assays for large-scale detection of total antibodies (total-Ab) and immunoglobulin (Ig) G and M against SARS-CoV-2 antigens have been developed, but there are limited data on the diagnostic accuracy of these assays. | 2021-02-12 |
| 33574179 | And since COVID-19 positive persons have a specific volatilome different from non-infected persons, they can be recognised by the dogs, by sniffing different body fluids consequently aiding in the diagnosis of COVID-19. […] Possible applications of dogs as COVID-19 detectors will be an easy real-time mobile diagnostic aid with low cost and good performance. | 2021-02-12 |
| 33574897 | Low- and middle-income countries have needed to establish health strategies to combat the pandemic, many of which have collaterally affected the diagnosis and treatment of other illnesses. […] In recent decades, interventional cytopathology with fine-needle biopsy techniques has emerged as a minimally invasive, rapid, economical and effective procedure for diagnosing and staging cancer. | 2021-02-12 |
| 33574991 | Knowledge of incidence of these complications, lowering the threshold for diagnostic imaging in symptomatic patients and timely radiological detection can play a vital role in subsequent management of these critically ill patients. | 2021-02-12 |
| 33575149 | To determine the diagnostic accuracy of fully automated electro-chemiluminescence immunoassay (ECLIA) anti-SARS-CoV-2 serological test for detection of past SARS-CoV-2 infection and to be used in seroprevalence surveys. […] Diagnostic accuracy of anti-SARS-CoV-2 was 96.7% based on receiver-operating characteristic (ROC) curve analysis. | 2021-02-12 |
| 33575226 | These findings will guide the public health policymakers to understand the effects COVID-19 on preventive services and the risk of having an increased number of outbreaks for childhood communicable disease, cancer cases with delayed diagnosis due to the screening services suspension. | 2021-02-12 |
| 33575241 | NPS utility in the diagnostic algorithm of COVID-19 should be reconsidered. | 2021-02-12 |
| 33575413 | The infected patient presents with varying non-specific symptoms requiring an accurate and rapid diagnostic tool to detect SARS-CoV-2. […] The findings are discussed in three main thematic areas namely diagnostic approaches, therapeutic options, and potential vaccines in various phases of development. | 2021-02-12 |
| 33575501 | Several immunochromatography kits of the antibody for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed, but it is still unclear which kits have high diagnostic value. […] This study aims to evaluate the accuracy rate for antibody detection of each immunochromatography kit and reveal which kit has a high diagnostic value for antibody detection. […] Evidence from large population studies of immunochromatography kits is needed to clarify the details of diagnostic value for SARS-CoV-2. | 2021-02-12 |
| 33575808 | Self-reported smell or taste impairment was prospectively evaluated by SNOT-22 at diagnosis, 4-week, 8-week, and 6-month. […] At 6 months from the diagnosis, psychophysical evaluation of olfactory function was also performed using the 34-item culturally adapted University of Pennsylvania Smell Identification Test (CA-UPSIT). 145 completed both the 6-month subjective and psychophysical olfactory evaluation. […] Despite most patients report a subjectively normal sense of smell, we observed a high percentage of persistent smell dysfunction at 6 months from the diagnosis of SARS-CoV-2 infection, with 11.7% of patients being anosmic or severely microsmic. | 2021-02-12 |
| 33575849 | Heightened awareness about the clinical and imaging presentation of COVID-19-related AHLE can positively alter the outcome in a select few by enabling early diagnosis and aggressive management. | 2021-02-12 |
| 33576014 | This report and existing published literature indicate diagnostic challenges and poor outcomes of CAPA in ICU-patients. | 2021-02-12 |
| 33576155 | Physicians’ gestalt is central in the diagnostic pipeline of suspected COVID-19, due to the absence of a single tool allowing conclusive rule in or out. […] The aim of this study was to estimate the diagnostic test characteristics of physician’s gestalt for COVID-19 in the ED, based on clinical findings or on a combination of clinical findings and bedside imaging results. of April 2020, patients with suspected COVID-19 were prospectively enrolled in two EDs. […] The final diagnosis was adjudicated after independent review of 30-day follow-up data. […] In suspected COVID-19, CG and CBIIG have fair diagnostic accuracy, in line with physicians’ gestalt for other acute conditions. | 2021-02-12 |
| 33576536 | We aimed to identify their clinical characteristics to help early diagnosis. […] In terms of COVID-19 pneumonia and influenza A pneumonia, fatigue, ground-glass opacity, and higher level of albumin tend to be helpful for diagnosis of COVID-19 pneumonia, while older age, higher temperature, and higher level of monocyte count tend to be helpful for the diagnosis of influenza A pneumonia. | 2021-02-12 |
| 33576704 | TMAS was able to aid professional sailors as well as passengers/recreational sailors in terms of telemedicine (diagnosis and monitoring), logistics (barrier actions and isolation), and operations (evacuation and repatriation). | 2021-02-12 |
| 33576712 | Research from the current and past pandemics supports the association between transdiagnostic constructs-anxiety sensitivity (AS), disgust, and intolerance of uncertainty (IU)-and pandemic-related distress. […] Recent research suggests a moderating effect of disgust on the relationship of AS-physical concerns and COVID-19-related distress, suggesting that transdiagnostic constructs underlie individual differences in activation of the behavioral immune system (BIS). […] No previous study has examined the independent and conjoint effects of pre-COVID-19 AS-physical concerns, disgust propensity (DP), disgust sensitivity (DS), and IU in this context; thus, we did so using longitudinal survey data (N = 3,062 Canadian and American adults) with simple and moderated moderations controlling for gender, mental health diagnosis, and COVID-19 diagnosis. | 2021-02-12 |
| 33576721 | Furthermore, PN practitioners trained to utilize emerging techniques and services can help prepare society to meet our modern immune challenges. | 2021-02-12 |
| 33576733 | This research letter presents a cluster of severe medical conditions that were delayed in diagnosis due to postponed presentation to healthcare facilities during the COVID-19 pandemic. | 2021-02-12 |
| 33576819 | Number of hospital admissions by primary diagnosis for each encounter. | 2021-02-12 |
| 33576820 | This multicenter, single health system randomized clinical factorial open-label trial enrolled 214 adult patients with a diagnosis of SARS-CoV-2 infection confirmed with a polymerase chain reaction assay who received outpatient care in sites in Ohio and Florida. | 2021-02-12 |
| 33576823 | Two (4.3%) patients had acute vascular nephropathy, while eight (17%) had alternative diagnosis most likely unrelated to COVID-19. | 2021-02-12 |
| 33576926 | Additionally, C-reactive protein (CRP) and white blood cell (WBC) are the independent predictors for the diagnosis of MIS-C, particularly in the existence of conjunctival injection and rash. […] Conjunctival injection and higher CRP and low WBC count are reliable diagnostic parameters for MIS-C cases. […] • Higher CRP and low total WBC count are the independent predictors for the diagnosis of MIS-C. | 2021-02-12 |
| 33577066 | The aim of the present study was to assess the value of inflammatory factors procalcitonin (PCT), interleukin 6 (IL-6), and C-reactive protein (CRP) in the early diagnosis and evaluation of novel coronavirus pneumonia (COVID-19). | 2021-02-12 |
| 33577470 | According to Polish and global guidelines, the basis for diagnosis is molecular testing - real-time reverse transcriptasepolymerase chain reaction (RT-PCR). […] According to Polish and global guidelines, the basis for diagnosis is molecular testing, real-time reverse transcriptase-polymerase chain reaction (RT-PCR). | 2021-02-12 |
| 33577615 | The sensitivity of sVNT for the diagnosis of SARS-CoV-2 infection and its kinetics were determined. […] The sensitivity of sVNT for the diagnosis of SARS-CoV-2 infection was 99% (95% confidence interval (CI) 94.4-100%) and the specificity was 100% (95% CI 98.3-100%). […] It can be used clinically to aid diagnosis in both early and late infection especially in cases when the real-time RT-PCR results in weakly negative or weakly positive, and to determine the protective immune response from SARS-CoV-2 infection in patients. | 2021-02-12 |
| 33577728 | Since THI is a diagnosis of exclusion, other reasons that may cause ALP elevation should be ruled out. | 2021-02-12 |
| 33577957 | The worldwide demand for SARS-CoV-2 RT-PCR testing resulted in a shortage of diagnostic kits. […] RNA extraction step constitutes a major bottleneck to perform diagnostic. […] Despite a lower sensitivity for low viral loads, extraction-free reagents can provide a valuable option, cheaper, easier and less reagent consuming for SARS-CoV-2 diagnostic, especially in laboratory with lower experience and equipment for molecular assays. | 2021-02-12 |
| 33578017 | The detection of antibodies against the novel coronavirus SARS-CoV-2 is mandatory for the diagnosis, retrospective assessment of disease progression, and correct evaluation of the current infection situation in the population. […] Comparison of the control population with economic data makes it possible to validate the sampling set and therefore to determine diagnostic specificity. […] Using the chosen approach, it was shown that the Roche test achieved very good results in terms of diagnostic specificity, reproducibility and limit of detection. | 2021-02-12 |
| 33578396 | As this method provides a fast non-invasive diagnosis it should be further developed in a larger cohort for screening of communicable viral diseases. | 2021-02-12 |
| 33578829 | Through the diagnostic social-ecological system (SES) framework, this review paper aimed to investigate what and how the multifaceted social, physical, and governance factors affected the success level of seven selected Asia-Pacific countries (namely, South Korea, Japan, Malaysia, Singapore, Vietnam, Indonesia, and New Zealand) in combatting COVID-19. | 2021-02-13 |
| 33578973 | A rapid, sensitive and simple point-of-care (POC) nucleic acid diagnostic test is needed to prevent spread of infectious diseases. […] Paper-based toehold reaction, a recently emerged colorimetric POC nucleic acid diagnostic test, has been widely used for pathogen detection and microbiome profiling. | 2021-02-13 |
| 33578979 | Increased research on diagnostic tools is currently being implemented in order to assist with rapid identification of the virus, as mass diagnosis and containment is the best way to prevent the outbreak of the virus. […] This device needs to be sensitive, selective, and exhibit rapid diagnostic capabilities. […] Alongside the design, this review also discusses the detection principles, fabrication techniques, and applications of the biosensors. | 2021-02-13 |
| 33579329 | Nowadays, with the emergence of advanced biological techniques and substantial improvements in bio-engineered materials, strategies have been developed to overcome clinical challenges in MSC application. | 2021-02-13 |
| 33579344 | We present the ‘Contactless’ model, a comprehensive operational tool including a plurality of services delivered remotely, structured according to a complexity gradient, aimed to cover diagnostic procedures and monitor disease progression in chronic pediatric patients. | 2021-02-13 |
| 33579579 | New diagnostic algorithms considering age and chronic conditions may ease Covid-19 diagnosis and optimize health resources allocation. | 2021-02-13 |
| 33579697 | It combines point-of-care diagnosis with next-generation sequencing, aiming to achieve population-scale testing. | 2021-02-13 |
| 33579729 | Respondents with an underlying diagnosis of IBD and over 18 years of age were included. […] 60.5% of respondents fulfilled DASS criteria for at least moderate depression, anxiety or stress. 45% reported a pre-existing diagnosis of depression and/or anxiety. […] Of those without a pre-existing diagnosis of anxiety or depression, high rates of at least moderate to severe depression (34.9%), anxiety (32.0%) and stress (29.7%) were noted. | 2021-02-13 |
| 33579730 | Evaluation of compatibility of eNAT with Cepheid Xpert Xpress SARS-CoV-2 assay demonstrated equivalent diagnostic accuracy and sensitivity compared to VTM. | 2021-02-13 |
| 33579769 | Importantly, African-American race and Hispanic ethnicity were associated with antibody positivity even after adjusting for personal COVID-19 diagnosis status, suggesting the contribution of unmeasured structural or societal factors. […] The size and diversity of our study population, combined with robust survey and modelling techniques, provide a vibrant picture of the demographic factors, exposures and symptoms that can identify individuals with susceptibility as well as potential to mount an immune response to COVID-19. | 2021-02-13 |
| 33579939 | For postmenopausal patients, our data provide strong support for the use of ER and PgR status at diagnosis for triaging of patients into three groups in which (taking into account clinical factors): (i) NeoET is likely to be inappropriate (Allred ER <6 or ER 6 and PgR <6) (ii) a biopsy for Ki67 analysis (on-treatment Ki67) could be considered after 2-4 weeks of NeoET (a: ER 7 or 8 and PgR <6 or b: ER 6 or 7 and PgR ≥6) or (iii) NeoET is an acceptable course of action (ER 8 and PgR ≥6). | NA |
| 33581714 | Rapid diagnosis of SARS-CoV-2 during pandemic enables timely treatment and prevention of COVID-19. […] Evaluating the accuracy and reliability of rapid diagnostic testing kits is crucial for surveillance and diagnosis of SARS-CoV-2 infections in general population, injection drug users, multi-transfused populations, healthcare workers, prisoners, barbers and other high risk populations. […] The RDTs evaluated in this study showed limited sensitivities in comparison to gold standard RT-PCR, indicating that there is a dire need in Pakistan for development of suitable testing to improve accurate COVID-19 diagnosis in line with national demands. | 2021-02-14 |
| 33581843 | Nucleic acid testing (NAT) plays an important role in rapid laboratory diagnosis, treatment assessment, epidemic prevention and control of COVID-19. […] However, since COVID-19 is caused by a new emerging virus and NAT for COVID-19 has not been clinically applied before, false negative results inconsistent with clinical diagnosis have appeared in clinical practice. | 2021-02-14 |
| 33581991 | WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: During the COVID-19 pandemic it is important to keep mesenteric ischemia in the differential diagnosis of unexplained abdominal pain. | 2021-02-14 |
| 33582382 | The present analysis aims to evaluate the consequences of a 2-month interruption of mammographic screening on breast cancer (BC) stage at diagnosis and upfront treatments in a region of Northern Italy highly affected by the severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) virus. […] The 2-month stop in mammographic screening produced a significant decrease in in situ BC diagnosis (-10.4%) and an increase in node-positive (+11.2%) and stage III BC (+10.3%). […] Despite screening interruption, procedures to establish a definitive diagnosis and treatment start were subsequently carried out without delay. | 2021-02-14 |
| 33582454 | Serological testing is important method for diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. | 2021-02-14 |
| 33582903 | A diagnosis of secondary hemophagocytic lymphohistiocytosis (sHLH) was made when the patients had an HScore greater than 169. […] The interval from the onset of symptom of COVID-19 to the time of a diagnosis of sHLH made was 19 days and the interval from the diagnosis of sHLH to death was 4 days. | 2021-02-14 |
| 33583231 | Two weeks following COVID-19 diagnosis, he reported profund vision loss (counting fingers) in his right eye where central retinal artery occlusion (CRAO) was detected on fundoscopic examination. […] This is the first case that reports PAMM in the setting of CRAO following COVID-19 diagnosis. | 2021-02-15 |
| 33583292 | The aim of this study was to evaluatethe diagnostic yield and the proportionality of this pre-procedural screeningprotocol. | 2021-02-15 |
| 33583710 | D dimer values ≥ 1 500 ng/mL were diagnostic of VTE, with a sensitivity of 80% and a specificity of 42%. | 2021-02-15 |
| 33583739 | Moreover, decreased minimal lung compliance was correlated to VAP and higher SOFA score at VAP diagnosis was associated with lethality. | 2021-02-15 |
| 33583973 | To define diagnostic criteria for coronavirus disease 2019 (COVID-19) on computed tomography (CT); to study the correlation between CT and polymerase chain reaction (PCR) testing for infection with severe acute respiratory syndrome coronavirus 2; and to determine whether the extent of parenchymal involvement and the need for mechanical ventilation are associated with the CT findings and clinical characteristics of patients with COVID-19. […] The patterns of CT findings are useful for the diagnosis of COVID-19 and the evaluation of disease severity criteria. | 2021-02-15 |
| 33584016 | Early diagnosis of COVID-19, which not only prevents the disease from spreading further but allows more reasonable allocation of limited medical resources. […] The quantitative indicators show that the proposed method only uses a GPU can reach the best performance, up to 0.87 and 0.86, respectively, compared with some widely used and recent deep learning methods, which are helpful for COVID-19 diagnosis and patient triage. | 2021-02-15 |
| 33584148 | Provide an updated review of the clinical management and diagnosis of Kawasaki disease with inclusion of potential diagnostic difficulties with multisystem inflammatory syndrome in children (MIS-C) given the ongoing COVID-19 pandemic. | 2021-02-15 |
| 33584157 | Therefore, it has become very important to develop deep learning-based applications that automatically detect COVID-19 cases using chest X-ray images to assist specialists and radiologists in diagnosis. | 2021-02-15 |
| 33584530 | Clinical, laboratory, and electrodiagnostic findings in these patients were unequivocally consistent with myopathy. | 2021-02-15 |
| 33585015 | Therefore, the establishment of complementary, multilateral, and cost-effective measures for the treatment of symptomatic and early diagnosis and isolation of asymptomatic cases/contacts are strongly recommended because of low ascertainment rate and large number of infected cases. | 2021-02-15 |
| 33585153 | Specifically, chest X-ray images have been the focus of many investigations that apply artificial intelligence techniques for the automatic classification of this disease. […] This research discusses some of the problems found in the current scientific literature on the application of artificial intelligence techniques in the automatic classification of COVID-19. | 2021-02-15 |
| 33585176 | For differential, early and initial, diagnosis of COVID-19, complaint of the smell dysfunctions, and impairment butanol threshold may be a distinctive indicator. | 2021-02-15 |
| 33585177 | ENT symptoms can be considered as biomarkers for early diagnosis of Covid-19 patients ensuring faster treatment and isolation allowing better containment of the disease. | 2021-02-15 |
| 33585511 | A three-dimensional (3D) deep learning method is proposed, which enables the rapid diagnosis of coronavirus disease 2019 (COVID-19) and thus significantly reduces the burden on radiologists and physicians. […] Lastly, by inputting the COVID-19 graph into GCN, we obtain the final diagnosis results. | 2021-02-15 |
| 33585674 | A 48-year-old man with no previous history of lung disease was admitted to the emergency room with a diagnosis of acute respiratory failure due to SARS-COV2. | 2021-02-15 |
| 33585713 | The benefits and limitation of various AM techniques are discussed, as well as considerations for a scalable manufacture of a polyHIPE-based RPE. | 2021-02-15 |
| 33585724 | All patients seen during the studied time periods with a diagnosis of chalazion or hordeolum were identified through review of electronic medical records and included in the study. | 2021-02-15 |
| 33585726 | About half of the services had collaborators and patients during radiotherapy with a positive diagnosis of COVID-19. | 2021-02-15 |
| 33585793 | The goals of this review are to explore the techniques of 3D printing for the equipment that are used for COVID-19 battle and evaluate the materials that are used for manufacturing and the manufactured equipment. | 2021-02-15 |
| 33585881 | Fever, fatigue, myalgia, loss of taste/smell and headache were associated with increased odds of a Covid-19 diagnosis among symptomatic self-referred HCWs compared with those had negative swab results. | 2021-02-15 |
| 33586113 | We aimed to identify the rate of thrombotic complications in ICU-treated patients with COVID-19, to inform recommendations for diagnosis and management. | 2021-02-15 |
| 33586431 | Importantly, CALIBURN allowed accurate diagnosis of clinical samples with extremely low viral loads, which is a major obstacle for the clinical applications of existing CRISPR diagnostic platforms. […] Our results suggest that CALIBURN can serve as a versatile platform for the diagnosis of COVID-19 and other respiratory infectious diseases. | 2021-02-15 |
| 33587262 | For this reason, a rapid alternative diagnostic option should be introduced as an automated detection method to prevent COVID-19 spreading among individuals. | 2021-02-15 |
| 33587451 | We included all consecutive patients admitted to the hospital between February 26 and May 15, 2020 with a confirmed diagnosis of COVID-19. | 2021-02-15 |
| 33587810 | 150 COVID-19 patients were reviewed at St James’s Hospital Dublin between May and September 2020 at a median of 80.5 (range 44 - 155) days after initial diagnosis. | 2021-02-15 |
| 33588050 | Predictive value of thiol parameters in the diagnosis of COVID-19 and in the determining its severity, and its correlation with presence and duration of symptoms were investigated. […] NT and TT levels have a strong predictive value in the diagnosis of COVID-19 and in determining disease severity. | 2021-02-15 |
| 33588121 | Currently, the chest CT is regarded as a popular and informative imaging tool for COVID-19 diagnosis. | 2021-02-15 |
| 33588226 | A cross-sectional study starting on March 29 to April 5, 2020 based on a national online survey using snowball sampling techniques was conducted. | 2021-02-15 |
| 33588737 | The diagnostic performance of the variables was assessed using receiver operating characteristic (ROC) analysis was used. | 2021-02-16 |
| 33588968 | The overall average score of the disease-related knowledge of patients with COVID-19 was (79.19 ± 14.25), the self-care situation was positively correlated with knowledge of prevention and control (r=0.265, P=0.004) and total score of disease-related knowledge (r= 0.206, P= 0.025); the degree of anxiety was negatively correlated with the knowledge of diagnosis and treatment (r= -0.182, P= 0.049). […] It was recommended that we should pay more attention to the elderly and low-income groups, and increase the knowledge about diagnosis and treatment of COVID-19 and self-care in the future health education for patients. | 2021-02-16 |
| 33589119 | Timely diagnosis is essential for the containment of the disease and breaks in the chain of transmission of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). […] The present situation demands the countries to scale up their testing and design innovative strategies to conserve diagnostic kits and reagents. […] The pooling of samples saves time, workforce and most importantly diagnostic kits and reagents. | 2021-02-16 |
| 33589129 | This study aims to provide scientific basis for rapid screening and early diagnosis of the coronavirus disease 2019 (COVID-19) through analysing the clinical characteristics and early imaging/laboratory findings of the inpatients. […] Personalised criteria should be formulated according to different age groups in the early screening and diagnosis stage. | 2021-02-16 |
| 33589130 | The relevance, mode of operation and value addition of this essential public health service are discussed in the context of inter departmental collaboration and interaction with other institutes through the existing diagnostic, surveillance and infection control networks. | 2021-02-16 |
| 33589177 | Since the whole genome sequences of a number of strains of this novel RNA virus were available in the public domain by early January 2020, a number of real-time polymerase chain reaction (RT-PCR) protocols were designed and used for diagnosis of this infection. | 2021-02-16 |
| 33589192 | In the absence of effective treatment or vaccine, the current strategy for the prevention of further transmission of severe acute respiratory syndrome (SARS) CoV-2 (COVID-19) infection is early diagnosis and isolation of cases. […] The diagnosis of SARS-CoV-2 is done by detecting viral RNA in the nasopharyngeal and throat swabs by real-time polymerase chain reaction (PCR). | 2021-02-16 |
| 33589202 | In the current COVID-19 crisis, many national healthcare systems are confronted with a huge demand for mass testing and an acute shortage of diagnostic resources. | 2021-02-16 |
| 33589846 | There was a decline of -37% regarding overall cases during lockdown, -9.4% of early diagnosis cases and -35% regarding specialized medical consultancy (4 specialized practices). […] After lockdown the overall case numbers were significantly reduced with -17.1% in comparison to 2019, the early diagnosis cases caught up nearly completely with +9.4% and also the specialized care showed catch-up effects with +7%. | 2021-02-16 |
| 33589862 | Coronavirus disease (Covid-19) has been spreading all over the world and its diagnosis is attracting more research every moment. | 2021-02-16 |
| 33590456 | A swab test is considered the gold standard for the diagnosis of COVID-19 despite the high number of false negatives. […] Radiologists play a crucial role in the rapid identification and early diagnosis of pulmonary involvement. | 2021-02-16 |
| 33590575 | After the medical staff prepared for isolation and protection, the patients quickly underwent with series of diagnostic tests, such as laboratory, imaging, and SARS-COV-2 nucleic-acid examinations. | 2021-02-16 |
| 33590670 | Diagnostic radiographers reported increased procedural pressure on mobile radiography, computed tomography and general radiography. […] There was no difference in PPE supply reported by diagnostic radiographers and radiation therapists except for hand sanitiser (P = 0.003). | 2021-02-16 |
| 33590675 | We enrolled all adult SOT recipients at our center with confirmed SARS-CoV-2 infection who underwent antibody testing with a single commercially available anti-nucleocapsid antibody test at least 7 days after diagnosis in a retrospective cohort. […] In the final multivariable model, the years from transplant to diagnosis (OR 1.26, p=0.002) and baseline immunosuppression with more than 2 agents (OR 0.26, p=0.03) were significantly associated with the antibody test result, controlling for kidney transplantation. | 2021-02-16 |
| 33590992 | Despite improvement in patient’s respiratory status, abdominal pain worsened and clinical signs and symptoms progressed to a diagnosis of acute pancreatitis 4 days after initiation of remdesivir therapy. | 2021-02-16 |
| 33591004 | These findings provide a rationale to consider plasma exchange as a therapeutic option in COVID-19 and to include von Willebrand factor and ADAMTS13 in the diagnostic workup. | 2021-02-16 |
| 33591793 | The patients were divided by diagnosis into COVID (COVID-19 infection) or CONTROL (an alternate diagnosis). […] DiscussionMathematically combining the blood tests has the potential to assist clinical acumen allowing for rapid streaming and more accurate patient flow pending definitive diagnosis. | 2021-02-16 |
| 33592050 | Profession, gender, age and date of diagnosis were matched for 186 case-control pairs. | 2021-02-16 |
| 33592254 | Diagnostic work-up following any COVID-19 associated symptom will lead to extensive testing, potentially overwhelming laboratory capacity whilst primarily yielding negative results. | 2021-02-16 |
| 33592533 | The presence of these symptoms could facilitate the diagnosis of suspected COVID-19 disease and the earlier selection of those that require confirmatory tests. | 2021-02-16 |
| 33592682 | The prevalence of high level of PTSD symptoms (PCL-5 > =33, a probable diagnosis of PTSD) was 10.7%. | 2021-02-16 |
| 33592692 | A rapid diagnosis of the Covid-19 and a generalized testing protocol is essential to fight against the pandemic and to maintain health control in the population. […] Principal biosensing and diagnostic technologies used to monitor the spread of the SARS-CoV-2 are based on specific genomic analysis and rapid immune tests, both with different technology platforms that include advantages and disadvantages. […] Most of the in vitro diagnosis companies are competing to be the first on validating under different regulations their technology for placing their platforms for Covid-19 detection as fast as possible in this big international market. […] A comprehensive analysis of the commercialized technologies for the genomic based sensing and the antibody/antigen detection methods devoted to Covid-19 diagnosis is described in this review, which have been detailed and listed under different countries regulations. | 2021-02-17 |
| 33592734 | Diagnostic tools play significant roles in the fight against COVID-19 and other pandemics. […] In this review, we consolidate the newly developed diagnostic tools for COVID-19 using emerging biosensing technologies and discuss their application promise. | 2021-02-17 |
| 33592878 | Most of the severe-critically ill COVID-19 patients became deteriorated in 2 weeks after diagnosis. | 2021-02-17 |
| 33593219 | Given the infectious nature of the SARS-CoV-2, fast and accurate diagnosis tools are important to detect the virus. […] In this review, we discuss the different diagnostic tests that are currently implemented in laboratories and provide a description of various COVID-19 kits. […] We summarize molecular techniques that target the viral load, serological methods used for SARS-CoV-2 specific antibodies detection as well as newly developed faster assays for the detection of SARS-COV 2 in various biological samples. […] In the light of the widespread of the pandemic, the massive diagnosis of COVID-19, using various detection techniques, appears to be the most effective strategy for monitoring and containing its propagation. | 2021-02-17 |
| 33593629 | Brain magnetic resonance imaging and laboratory tests were normal, a 0.125% pilocarpine test confirmed the diagnosis. | 2021-02-17 |
| 33593636 | POCUS parameters have the potential to impact the diagnosis, management, and prognosis of patients with confirmed or suspected COVID-19. | 2021-02-17 |
| 33593710 | Currently, PCR assay is a golden standard for diagnosis of Covid-19. […] Therefore, this can serve as a powerful diagnostic tool, needed in the frontline of the clinic and hospitals. | 2021-02-17 |
| 33593750 | Type 2 diabetes was defined as previous diagnosis or treatment with diabetes medication, undiagnosed diabetes and pre-diabetes using glycosylated hemoglobin (HbA1c) American Diabetes Association (ADA) criteria and de novo or intrahospital hyperglycemia as fasting plasma glucose (FPG) ≥140 mg/dL. | 2021-02-17 |
| 33594159 | Additionally, diagnostic time of DL-MLP was more efficient than radiologists (38 s vs 5.15 min). | 2021-02-17 |
| 33594297 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological tests have been suggested as an additional diagnostic tool in highly suspected cases with a negative molecular test and determination of seroprevalence in population. […] We compared the diagnostic performance of eight commercial serological assays for IgA, IgM, and IgG antibodies to the SARS-CoV-2 virus. […] Diagnostic accuracy for IgG ELISA and CIA assays were excellent (AUC ≥ 0.90), without significant difference. […] IgA showed significantly better diagnostic accuracy than IgM (P < 0.001). | 2021-02-17 |
| 33594345 | After unsuccessful femoral artery access, the diagnostic angiography and the right coronary artery percutaneous coronary intervention were successfully performed from ultrasound-guided lower superficial temporal artery access. […] We showed that superficial temporal access can be used as an alternate access site for diagnostic coronary angiography and intervention when standard wrist and femoral access sites are not readily accessible. | 2021-02-17 |
| 33594347 | Myocarditis is a challenging diagnosis due to heterogeneity of clinical presentation, ranging from mild symptoms to fatal arrhythmia and cardiogenic shock (CS). […] However, the diagnosis is often made on medical history, clinical presentation, magnetic resonance imaging, and blood tests. | 2021-02-17 |
| 33594623 | Serological testing may be helpful for the diagnosis of suspected patients with negative RT-PCR results and for the identification of asymptomatic infections. | 2021-02-17 |
| 33595397 | The coronavirus disease 2019 (COVID-19) pandemic has highlighted the cardinal importance of rapid and accurate diagnostic assays. […] Molecular diagnostic assays are a major group of tests used to diagnose COVID-19. […] Other diagnostic molecular methods, including CRISPR-based assays, isothermal nucleic acid amplification methods, digital PCR, microarray assays, and next generation sequencing (NGS), are promising alternatives. […] In this review, we summarize the technical and clinical applications of the different COVID-19 molecular diagnostic assays and suggest directions for the implementation of such technologies in future infectious disease outbreaks. | 2021-02-17 |
| 33595414 | Transdiagnostic factors, such as anxiety sensitivity, could be an important component to understand how individuals experience COVID-19 specific fear, depression and anxiety. | 2021-02-17 |
| 33595506 | The most common ocular diagnosis was open globe injury (40.8%) in the COVID-19 period and microbial keratitis (47.9%) in the pre-COVID-19 period. | 2021-02-17 |
| 33595513 | Surgical techniques were performed ex vivo using the electrosurgical device, scalpel, and mechanized drill on the muscle and bone of commercially available chicken. […] The quantification of the aerosol generation will help surgeons take practical decisions in their surgical techniques in the pandemic era. | 2021-02-17 |
| 33595524 | Timely diagnosis and intervention have prevented a fatal outcome. | 2021-02-17 |
| 33595767 | In the LICs, there is a low capacity of outbreak response which is reflected by the significantly lower number of diagnostic tests. | 2021-02-17 |
| 33595844 | Consensus was completely reached on the item “Diagnostic” (100%), The field with the lowest consensus was “Demand for treatment with dental implants” (37.5%). | 2021-02-17 |
| 33595924 | On the other hand, the rise in the overall malignancy rate reflects the importance of prioritizing diagnostic procedures for patients at high oncological risk. | 2021-02-17 |
| 33596036 | Early diagnosis of SARS-CoV-2 infection is critical for facilitating proper containment procedures, and a rapid, sensitive antigen assay is a critical step in curbing the pandemic. […] SAb-functionalized FET sensors also exhibited good sensing performance in discriminating positive and negative clinical samples, indicating a proof of principle for use as a rapid COVID-19 antigen diagnostic tool with high analytical sensitivity and specificity at low cost. | 2021-02-17 |
| 33596179 | Because of the rapid and serious nature of acute cardiovascular disease (CVD) especially ST segment elevation myocardial infarction (STEMI), a leading cause of death worldwide, prompt diagnosis and treatment is of crucial importance to reduce both mortality and morbidity. | 2021-02-17 |
| 33596236 | Imprecision, diagnostic sensitivity and specificity and concordance were evaluated on IgG serologic assays from EuroImmun, Epitope Diagnostics (EDI), Abbott Diagnostics and DiaSorin and a rapid IgG/IgM test from Healgen. […] Diagnostic sensitivity of the assays was 100% (CI: 80-100%) for Abbott, EDI and EuroImmun and 95% (CI: 73-100%) for DiaSorin at ≥14 days post PCR. […] Only the Abbott assay had a diagnostic specificity of 100% (CI: 91-100%). | 2021-02-17 |
| 33596239 | The rapid emergence of coronavirus disease 2019 (COVID-19) as a global pandemic affecting millions of individuals globally has necessitated sensitive and high-throughput approaches for the diagnosis, surveillance, and determining the genetic epidemiology of SARS-CoV-2. | 2021-02-17 |
| 33596245 | Our preliminary data may provide valuable information and promising biomarkers for the diagnosis of the disease and, when validated in larger cohort, it could facilitate the stratification of patients based on the microbial signature. | 2021-02-17 |
| 33596462 | Whilst seventy women (11.4%) reported a current clinical diagnosis of depression, two hundred and sixty-four women (43%) reported a score of ≥13 on the EPDS, indicating clinically relevant depression. […] Whilst one hundred and thirteen women (18.4%) reported a current clinical diagnosis of anxiety, three hundred and seventy-three women (61%) reported a score of ≥40 on STAI-S, indicating clinically relevant anxiety. | 2021-02-17 |
| 33596475 | Responders were asked to include all patients admitted for the surgical drainage of a head and neck abscess of odontogenic origin during the first 2020 lockdown period, and in a similar time frame in 2018 and 2019 (control group), based on screening the French diagnostic and therapeutic classification of medical acts. | 2021-02-17 |
| 33596516 | The inadequacy of conventional diagnostic tools in terms of time consuming and complex laboratory-based diagnosis process is a major challenge to medical care. […] In addition, POCT devices also play a crucial role in preventing the transmission of infectious diseases by offering real-time testing and lab quality microbial diagnosis within minutes. […] Timely diagnosis and further treatment optimization facilitate the containment of outbreaks of infectious diseases. | 2021-02-17 |
| 33596605 | Telemedicine-conveying medical information virtually for planning, diagnosis, or treatment-has been a part of the American medical system for over 100 years. […] The purpose of this article is to provide an overview of the need for telepractice prior to and beyond the current pandemic, the efficacy of telepractice for the voice-specialized SLP, limitations of telepractice, and best practices for providing care over telepractice with a specific focus on voice disorder diagnosis and treatment. | 2021-02-17 |