AHR


aryl hydrocarbon receptor


ENTREZID: 196 | Type: Protein Coding | Map: 7p21.1

OMIM: 267430 | 145500 | 106165


Summary Entrez
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]