CD74
CD74 molecule
Gene Context Sentence
Table 2. Analysis of context sentence of CD74 gene in 1 abstracts.
| PMID | Gene Context Sentence |
|---|---|
| 32855215 | CIITA induces resistance by activating expression of the p41 isoform of invariant chain CD74, which inhibits viral entry by blocking cathepsin-mediated processing of the Ebola glycoprotein. […] We further show that CD74 p41 can block the endosomal entry pathway of coronaviruses, including SARS-CoV-2. […] These data therefore implicate CIITA and CD74 in host defense against a range of viruses, and they identify an additional function of these proteins beyond their canonical roles in antigen presentation. |