CD74 molecule

Gene Context Sentence

Table 2. Analysis of context sentence of CD74 gene in 1 abstracts.

PMID Gene Context Sentence
32855215 CIITA induces resistance by activating expression of the p41 isoform of invariant chain CD74, which inhibits viral entry by blocking cathepsin-mediated processing of the Ebola glycoprotein. […] We further show that CD74 p41 can block the endosomal entry pathway of coronaviruses, including SARS-CoV-2. […] These data therefore implicate CIITA and CD74 in host defense against a range of viruses, and they identify an additional function of these proteins beyond their canonical roles in antigen presentation.