Gene Context Sentence
Table 2. Analysis of context sentence of CD28 gene in 3 abstracts.
|PMID||Gene Context Sentence|
|32324595||The costimulatory molecule CD28 had opposite results.|
|33014780||Then, after gene expression profiling experiments, we found that several “antiviral” genes, such as CD28 and IFN gamma, were upregulated, while genes with “proviral” action, such as ARG-1, CEACAM1, and FUT4, were less expressed during treatment with imatinib, thus demonstrating that TKIs are not detrimental from the immunological point of view.|
|33033851||In 2006, six healthy volunteers received TGN1412, a CD28 superagonist antibody, in a first-in-man clinical trial and suffered from cytokine storm.|