CD6 molecule

Gene Context Sentence

Table 2. Analysis of context sentence of CD6 gene in 7 abstracts.

PMID Gene Context Sentence
32700604 Itolizumab, an anti-CD6 humanized IgG1 mAb, binds to domain-1 of CD-6 that is responsible for priming, activation, and differentiation of T-cells.
33015549 Itolizumab, an anti-CD6 monoclonal antibody, has been recently approved for the off-label indication of cytokine release syndrome in the background of COVID-19, by the Drug Controller General of India.
33048300 Itolizumab is a first-in-class anti-CD6 monoclonal antibody that was initially developed for various cancers and was later developed and approved in India for treatment of moderate to severe chronic plaque psoriasis in 2013.
33105142 Based on the increased susceptibility to cytokine release syndrome, inducing respiratory and systemic complications in this population, 19 patients were included in an expanded access clinical trial to receive itolizumab, an anti-CD6 monoclonal antibody.
33292350 Itolizumab is a humanized recombinant anti-CD6 monoclonal antibody (MAb), with the ability of reducing serum interferon gamma (INF-γ), tumour necrosis factor alpha (TNFα) and IL-6.
33304584 CD6 is a glycoprotein expressed on mature T lymphocytes which is a crucial regulator of the T-cell activation. […] Itolizumab is a humanised antibody targeting CD6.
33397150 Itolizumab is a monoclonal antibody that recognizes human CD6 expressed in activated T cells.