TYK2
tyrosine kinase 2
Gene Context Sentence
Table 2. Analysis of context sentence of TYK2 gene in 2 abstracts.
| PMID | Gene Context Sentence |
|---|---|
| 33193390 | Specifically, the SOCS bind to the activation loop of receptor-associated tyrosine kinases JAK2 and TYK2 through the SOCS kinase inhibitory region (KIR), which inhibits STAT transcription factor activation by the kinases. |
| 33307546 | We identify potential targets for repurposing of licensed medications: using Mendelian randomisation we found evidence in support of a causal link from low expression of IFNAR2, and high expression of TYK2, to life-threatening disease; transcriptome-wide association in lung tissue revealed that high expression of the monocyte/macrophage chemotactic receptor CCR2 is associated with severe Covid-19. |