T cell receptor delta locus

Gene Context Sentence

Table 2. Analysis of context sentence of TRD gene in 3 abstracts.

PMID Gene Context Sentence
32811575 The COMPASS Pathways (COMPASS) phase 2b double-blind trial of psilocybin therapy in antidepressant-free, treatment-resistant depression (TRD) is underway to determine the safety, efficacy and optimal dose of psilocybin. […] However, the efficacy and safety of psilocybin therapy in conjunction with SSRIs in TRD is not yet known.
32978766 This study was designed to explore the related changes in daily life and impacts on the well-being of a group of patients with chronic treatment-resistant depression (TRD) during the COVID-19 pandemic. […] This study was a part of a long-term, follow-up study of a cohort of patients with TRD collected in 2018. […] The three emerging themes included: The threatening of homogeneity in the whole person’s health, the interaction between bio-psycho-social aspects, and positive growth of individuals with TRD. […] The COVID-19 pandemic has affected the health of patients with TRD in both positive and negative ways.
33157937 Treatment-resistant depression (TRD) has a high prevalence and can be exacerbated by poor physical health and economic hardships, which have become common stressors during the current COVID-19 pandemic. […] The main aim of this study will be to evaluate the effectiveness of an Internet-based adjuvant lifestyle-based intervention for patients with TRD. […] A total of 180 patients with TRD will be randomly allocated (1:1:1) to 1 of 3 groups: treatment prescribed by the mental health team and written suggestions for lifestyle changes (placebo control group); treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week mindfulness-based cognitive therapy program (active control group); or treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week lifestyle change promotion program (intervention group). […] Patients with TRD are especially vulnerable when face-to-face psychotherapy is unavailable. […] Our results may provide guidance for treatment of patients with TRD in future situations that require lockdown measures.