T cell receptor delta locus
Gene Context Sentence
Table 2. Analysis of context sentence of TRD gene in 3 abstracts.
|PMID||Gene Context Sentence|
|32811575||The COMPASS Pathways (COMPASS) phase 2b double-blind trial of psilocybin therapy in antidepressant-free, treatment-resistant depression (TRD) is underway to determine the safety, efficacy and optimal dose of psilocybin. […] However, the efficacy and safety of psilocybin therapy in conjunction with SSRIs in TRD is not yet known.|
|32978766||This study was designed to explore the related changes in daily life and impacts on the well-being of a group of patients with chronic treatment-resistant depression (TRD) during the COVID-19 pandemic. […] This study was a part of a long-term, follow-up study of a cohort of patients with TRD collected in 2018. […] The three emerging themes included: The threatening of homogeneity in the whole person’s health, the interaction between bio-psycho-social aspects, and positive growth of individuals with TRD. […] The COVID-19 pandemic has affected the health of patients with TRD in both positive and negative ways.|
|33157937||Treatment-resistant depression (TRD) has a high prevalence and can be exacerbated by poor physical health and economic hardships, which have become common stressors during the current COVID-19 pandemic. […] The main aim of this study will be to evaluate the effectiveness of an Internet-based adjuvant lifestyle-based intervention for patients with TRD. […] A total of 180 patients with TRD will be randomly allocated (1:1:1) to 1 of 3 groups: treatment prescribed by the mental health team and written suggestions for lifestyle changes (placebo control group); treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week mindfulness-based cognitive therapy program (active control group); or treatment prescribed by the mental health team, written suggestions for lifestyle changes, and an 8-week lifestyle change promotion program (intervention group). […] Patients with TRD are especially vulnerable when face-to-face psychotherapy is unavailable. […] Our results may provide guidance for treatment of patients with TRD in future situations that require lockdown measures.|