NLR family CARD domain containing 4

ENTREZID: 58484 | Type: NA | Map: 2p22.3

OMIM: 300335

Summary Entrez
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]