MOG


myelin oligodendrocyte glycoprotein


ENTREZID: 4340 | Type: Protein Coding | Map: 6p22.1

OMIM: 600754 | 277950


Summary Entrez
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]