Gene Context Sentence
Table 2. Analysis of context sentence of DMD gene in 2 abstracts.
|PMID||Gene Context Sentence|
|32485610||At the moment, little treatment options are available for Duchenne muscular dystrophy (DMD). […] The attention towards dietary supplements in DMD is rapidly increasing, with the aim to counteract pathology-related alteration in nutrient intake, the consequences of catabolic distress or to enhance the immunological response of patients as nowadays for the COVID-19 pandemic emergency. […] For most supplements, little research has been done and little evidence is available concerning their effects in DMD as well as their preventing actions against infections. […] Then, little is known about the real extent of supplement use in DMD patients. […] This review discusses the supplements mostly used by DMD patients, focusing on their potential toxicity, due to a variety of mechanisms including pharmacodynamic or pharmacokinetic interactions and contaminations, as well as on reports of adverse events. […] This overview underlines the need for caution in uncontrolled use of dietary supplements in fragile populations such as DMD patients.|
|32503092||Disease-modifying drugs (DMDs) may alter the immune status and thus increase the susceptibility to coronavirus disease 2019 (COVID-19) in patients with MS or neuromyelitis optica spectrum disorders (NMOSD). […] Information about MS and NMOSD disease duration and the usage of DMDs were collected. […] Eight hundred eighty-two of 1,804 (48.89%) patients with MS and 2,129 of 3,060 (69.58%) patients with NMOSD were receiving DMDs. […] There were no alterations in the patients’ DMD regimen during January 15, 2020, to March 15, 2020, the 3-month period. […] None of the patients with MS treated with DMDs had COVID-19. […] No increased risk of COVID-19 infection was observed in patients with MS or NMOSD, irrespective of whether these patients received DMDs.|