interferon regulatory factor 1
Gene Context Sentence
Table 2. Analysis of context sentence of IRF1 gene in 3 abstracts.
|PMID||Gene Context Sentence|
|32616594||Importantly, CsA induced interferon regulatory factor 1 (IRF1), a pronounced type-III-interferon (IFNλ) response and expression of antiviral genes. […] Down-regulation of IRF1 or IFNλ increased MERS-CoV propagation in presence of CsA.|
|33278357||Mechanistically, TNF-α and IFN-γ co-treatment activated the JAK/STAT1/IRF1 axis, inducing nitric oxide production and driving caspase-8/FADD-mediated PANoptosis.|
|33506741||Further, degree centrality analysis reveals that IRF1/9/7, TP53, and CASP3, UBA52, and UBC are vital proteins for IFN-γ-mediated signaling, apoptosis, and proteasomal degradation of CD4, respectively.|