interferon gamma

ENTREZID: 3458 | Type: Protein Coding | Map: 12q15

OMIM: 613254 | 609532 | 609423 | 609135 | 607948 | 147570

Summary Entrez
This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]