ADAR
adenosine deaminase RNA specific
Gene Context Sentence
Table 2. Analysis of context sentence of ADAR gene in 5 abstracts.
| PMID | Gene Context Sentence |
|---|---|
| 32589459 | Two RNA editing enzymes involved in antiviral responses, APOBEC3A, and ADAR-1 were also highly expressed. |
| 32596474 | We identify nucleotide changes that may be signatures of RNA editing: adenosine-to-inosine changes from ADAR deaminases and cytosine-to-uracil changes from APOBEC deaminases. […] However, the reduced ADAR signature in these data raises the possibility that ADARs might be more effective than APOBECs in restricting viral propagation. […] Our results thus suggest that both APOBECs and ADARs are involved in coronavirus genome editing, a process that may shape the fate of both virus and patient. |
| 32992592 | We reveal that host immune response via APOBEC and ADAR gene editing gives rise to near 65% of recorded mutations. |
| 33101175 | No correlation was found with other molecules associated with Coronavirus infection, including ADAR, BST2, IRF3, IFITM3, ISG15, MX1, MX2, RNASEL, RSAD2, and VPRBP. |
| 33234239 | In this brief review we describe three such human defense mechanisms, the apolipoprotein B mRNA editing catalytic polypeptide-like proteins (APOBEC), adenosine deaminase acting on RNA proteins (ADAR), and reactive oxygen species (ROS), and discuss their potential implications on SARS-CoV-2 evolution. |