Tissue Sentence Context

Table 1. Analysis of context sentence of retina tissue in 27 abstracts.

PMID Senteces
32316719 Real-time PCR was performed to quantify ACE2 and TMPRSS2 gene expression in conjunctiva, cornea, lacrimal gland, iris, lens, retina, lung, heart, kidney, and liver from male mice.
32461407 The aim of this article is to develop preferred practice patterns, by developing a consensus amongst the lead experts, that would help the institutes as well as individual vitreo-retina and uveitis experts to restart their practices with confidence.
32461415 The majority of the queries were directed to the department of cornea (34.15%), followed by retina (24.74%).
32469258 To report the presence of viral ribonucleic acid (RNA) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human retina in deceased patients with confirmed novel coronavirus disease 2019 (COVID-19). […] A sample of human retina was secured and fixed in RNAlater™. […] In three out of 14 eyes SARS-CoV-2 viral RNA was detected in the retina of deceased COVID-19 patients. […] As analysis for three different sequences (RdRp-gene, E-gene and Orf1 gene) revealed positive results in RT-PCR, the existence of SARS-CoV-2 viral RNA in human retina is proven according to the standards of the World-Health-Organization. […] Viral RNA of SARS-CoV-2 is detectable in the retina of COVID-19 patients.
32526045 Most previous applications have used UVC light emitted from broad spectrum 254-nm low-pressure mercury lamps, which, however, has undesirable, harmful effects on the skin and retina of mammals due to, among other things, biomolecule damage by mutagenic and carcinogenic bipyrimidine photoproducts.
32567041 To evaluate the risk of transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after exposure to a COVID-19+ physician in a retina clinic. […] Records of 142 patients and 11 staff members from a single retina clinic that were exposed to a COVID-19+ ophthalmologist were reviewed.
32611912 Retinal screening is unnecessary for coronavirus patients taking chloroquine or hydroxychloroquine as the probability of toxic damage to the retina is less due to short-duration of drug therapy.
32637738 Postmortem tissue procurement and preparation were performed with personal protective equipment (PPE) and the necessary protective measures. qRT-PCR-testing was performed for the following ocular tissues and fluids: conjunctival fluid swabs, bulbar conjunctiva, corneal epithelium, corneal stroma, corneal endothelium, anterior chamber fluid, lens, iris, vitreous, retina, uvea, sclera, and optic nerve.
32674481 Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene therapy is highly dependent on the proportion of successfully transduced cells. […] In this review, we explore the immunomodulatory activity of hydroxychloroquine and chloroquine, their impact on viral infections, and their potential to improve the efficacy and safety of retinal gene therapy by reducing AAV-induced immune responses. […] The safety and practicalities of delivering hydroxychloroquine into the retina will also be discussed.
32729633 ACE2 receptor is widely expressed in multiple organs, including the retina, an extension of the central nervous system. […] To assess whether there is any retinal disease associated with COVID-19. […] We have evaluated 27 asymptomatic subjects, with retinal fundoscopic, optical coherence tomography (OCT) and OCT angiography fourteen days after hospital discharge due to COVID-19 bilateral pneumonia.
32730210 Moreover, the proposed method can be easily extended to other similar clinical applications such as computer-aided detection and diagnosis of pulmonary nodules in CT images, glaucoma lesions in Retina fundus images, etc.
32735134 Papillophlebitis is a rare condition characterized by venous congestion and optic disc edema, which has been suggested to occur as a consequence of inflammation of the retinal veins or, possibly, the capillaries of the optic disc, leading to venous insufficiency and compression of the central retina vein. […] OS fundus examination showed dilated and tortuous retinal vessels, disc edema, and retinal hemorrhages.
32740067 To reduce disease transmission, national regulatory agencies temporarily recommended curtailment of all nonurgent office visits and elective surgeries in March 2020, including vitreoretinal outpatient care in the USA. […] The effect of these guidelines on utilization of vitreoretinal care has not been explored to date. […] Retinal outpatient visits, new patient visits, intravitreal antivascular endothelial growth factor injections and in-office multimodal retinal imaging has seen a significant decline in utilization in the early phase of the pandemic. […] Telemedicine visits, enabled by new national legislation for all areas of medicine, have been adopted to a modest degree by the retina community. […] In-office retinal care declined in response to the COVID-19 pandemic and national regulatory guidelines limiting nonurgent care. […] These trends in practice patterns and care utilization may be of interest to vitreoretinal providers and all ophthalmologists at large.
32748176 To evaluate diabetic retinopathy (DR) screening with a portable handheld smartphone-based retinal camera and telemedicine in an urban primary healthcare setting and to evaluate the learning curve for image acquisition, performed by healthcare personnel without previous experience in retinal imaging. […] After a brief training in image acquisition, there was further continuous feedback given by a retina specialist during the remote image reading process. […] A total of 627 adult individuals with T2DM underwent retinal evaluation.
32763298 Also, regular control of retina should be considered for patients under HCQ treatment.
32796445 These preliminary results can help the retina specialist community to foresee this unique scenario and to develop successful management strategies.
32803018 Two patients with seizure history present to a retina clinic for routine follow up.
32860621 Despite advances in ophthalmic diagnostics, the direct ophthalmoscope remains a key clinical skill taught to medical students and is the tool of choice for retina examination among non-ophthalmic physicians.
32883010 The ocular surface and retina have the necessary proteins, Transmembrane Serine Protease 2 (TMPRSS2), CD147, Angiotensin-Converting Enzyme 2 (ACE2) and Cathepsin L (CTSL) necessary to be infected with SARS-CoV-2.
32908681 Some reports described a possible ritonavir-related retinal toxicity. […] The objective of this research was to review and analyze previous studies conducted on ritonavir administration and retinal impairment in a narrative synthesis. […] PubMed was used to perform a systematic review of ritonavir effects and retinal damage. […] Seven single cases and one case series, reporting a total of 10 patients affected by retinal changes secondary to long-term ritonavir treatment, were included in the review. […] Variable degrees of outer retina and retinal pigment epithelium changes were detected in most of the patients, with two patients showing macular telangiectasia, four patients presenting intraretinal crystal deposits, two patients disclosing a bull’s eye maculopathy, and two patients revealing midperipheral bone spicule-like pigment changes. […] We aimed to alert ophthalmologists on the importance of recognizing ritonavir-induced retinal impairment in SARS-CoV-2 patients.
32946292 Recent studies demonstrated not only retinal impairments but also detected SARS-CoV-2 in the retina of patients with COVID-19. […] This letter discusses the retinal tropism of SARS-CoV-2, describing possible routes for this coronavirus to reach the retina and cellular mechanisms involved in the retinal cell infection. […] Determining how SARS-CoV-2 can affect the retinal tissue is essential for the development of new therapeutic strategies and preventive measures, as well as for understanding the possible relationship between COVID-19 damage to the retina and to the brain.
32955690 Viral RNA of COVID-19 has been detected in the retina of affected patients and recent publications highlight the possibility of retinal microangiopathy in patients with confirmed COVID-19 infection. […] Given the magnitude of the current pandemic, emphasis should be given to better reporting of clinically significant ocular symptoms, e.g. new scotoma, which could indicate the need for a retinal examination as well as follow-up testing after recovery from COVID-19.
32960319 To quantify the shrinking in outpatient and intravitreal injections’ volumes in a tertiary referral retina unit secondary to virus causing coronavirus disease 2019 (COVID-19). […] In this retrospective cross-sectional study, we reviewed the charts of all patients who had a visit at a medical retina referral center during the Italian quarantine (from 9th of March 2020 to 3rd of May 2020). […] The drop in intravitreal treatments was larger in patients with posterior uveitis, retinal vein occlusion, and diabetes (- 85.7%, - 61.9%, and - 59.6%, respectively).
32982151 To report the impact of COVID-19 on retina practices in three different “hot spot” cities in the United States. […] The authors assessed data of encounters and intravitreal injections from March 16th to May 8th 2020, at different offices specializing in retina in the United States. […] One practice was in an academic setting, one practice was in a private multispecialty setting, and one practice was a solo private vitreo-retina practice. […] The decline at Miami Ocular Oncology & Retina in Miami was 37% (1198 patients) in the encounters and 30% (867 patients) in the injections.
32983831 Viral RNA of COVID-19 has been detected in the retina of affected patients and recent publications highlight the possibility of retinal microangiopathy in patients with confirmed COVID-19 infection. […] Given the magnitude of the current pandemic, emphasis should be given to better reporting of clinically significant ocular symptoms, e.g. new scotoma, which could indicate the need for a retinal examination as well as follow-up testing after recovery from COVID-19.
32984785 We screened the fundus of patients with COVID-19 to detect alterations of the retina and its vasculature and to assess possible correlations with clinical parameters. […] The presence of retinal alterations in patients with COVID-19 and subjects unexposed to the virus was assessed using fundus photographs and their prevalence was compared. […] The influence of clinical/lab parameters on retinal findings was tested in COVID-19 patients. 54 patients and 133 unexposed subjects were enrolled. […] Retinal findings in COVID-19 included: haemorrhages (9·25%), cotton wools spots (7·4%), dilated veins (27·7%), tortuous vessels (12·9%). […] COVID-19 can affect the retina. […] Retinal veins diameter seems directly correlated with the disease severity.
33021856 Funduscopic examination revealed several retinal hemorrhages. […] Thrombotic complications associated with Covid-19 infection have high incidence and may involve the retina. […] We described a case of retinal involvement associated with Covid-19 infection. […] Funduscopic examination revealed retinal hemorrhages in a man with loss of vision.