Leydig

Cell Sentence Context


Table 1. Analysis of context sentence of adipocytes tissue in 12 abstracts.

PMID Senteces
32339391 In this Perspective, we argue that adipocytes and adipocyte-like cells, such as pulmonary lipofibroblasts, may play an important role in the pathogenic response to COVID-19. […] Expression of angiotensin-converting enzyme 2 (ACE2 - the functional receptor for SARS-CoV) - is upregulated in adipocytes of obese and diabetic patients, which turns adipose tissue into a potential target and viral reservoir. […] Similar to the recently established adipocyte-myofibroblast transition (AMT), pulmonary lipofibroblasts located in the alveolar interstitium and closely related to classical adipocytes, demonstrate the ability to transdifferentiate into myofibroblasts that play an integral part of PF.
32492562 Immune cells accumulate in visceral adipose tissue and together with paracrine adipocytes release a wide range of biologically active cytokines (including IL-1β, IL5, IL6 and IL8) that can result in both local, pulmonary and systemic inflammation.
32593740 RNA-seq data revealed 14857 genes expressed in human subcutaneous adipocytes, including genes mentioned above. […] Our results, in human subcutaneous adipocytes cell culture, indicate a positive effect of irisin on the expression of multiple genes related to viral infection by SARS-CoV-2; furthermore, translatable for other tissues and organs targeted by the novel coronavirus and present, thus, promising approaches for the treatment of COVID-19 infection as therapeutic strategy to decrease ACE2 regulatory genes.
32593832 This increase permeability further leads to translocation of microbial components such as MAMPs (microbial-associated molecular pattern), triggering an inflammatory immune response by TLR-expressing cells of the mesentery fat (mostly macrophages and adipocytes).
32647360 Leptin is secreted by adipocytes in proportion to body fat and regulates appetite and metabolism through signaling in the hypothalamus.
32649962 The adipose tissue also expresses ACE2, suggesting that adipocytes are potentially infected by SARS-CoV-2.
32825713 Caveolae are flask-shaped invaginations of the plasma membrane found in numerous cell types and are particularly abundant in endothelial cells and adipocytes.
32910704 We speculate that reducing the size of overgrown fat tissue by ultra-sharp blades and using near-normal adipocytes will create a ‘new normal.’
32938758 Hyperinsulinaemia promotes: magnesium depletion via increased renal excretion, reduced intracellular levels, lowers vitamin D status via sequestration into adipocytes and hydroxylation activation inhibition.
33114495 In this perspective article, we discuss group differences in the amount of visceral fat levels and the extent of inflammation in adipocytes of visceral fat tissue, which may, in part, drive population, cross-national, ethnic, and sex differences in COVID-19 disease.
33202598 White adipocytes express ACE-2 receptors in high concentration, especially in obese patients.
33503828 Hypothetically, high levels of visceral adiposity cause systemic inflammation, thus decreasing the ACE2 amount on the surface of both visceral adipocytes and alveolar epithelial type 2 cells in the lungs.