CD14

CD14 molecule

Gene Context Sentence

Table 2. Analysis of context sentence of CD14 gene in 15 abstracts.

PMID	Gene Context Sentence
32257537	In addition, a group of CD14+CD11c+CD11b^mid regulatory DC cell population dramatically increased.
32377375	There was an increased ratio of classical CD14⁺⁺ monocytes with high inflammatory gene expression as well as a greater abundance of CD14⁺⁺IL1β⁺ monocytes in the ERS.
32502135	Standardized quantitative assessment of mHLA-DR on CD14+ cells was performed using calibrated flow cytometry at baseline (ICU admission), and at days 3 and 5 after ICU admission. […] When compared to non-critically ill hospitalized COVID-19 patients, ICU patients with severe COVID-19 disease showed reduced mHLA-DR expression on circulating CD14+ monocytes at ICU admission, indicating a dysfunctional immune response.
32543740	On admission, compared to patients with poor prognoses, those with good prognoses had significantly higher counts of monocytes (p < 0.05), macrophages (p < 0.05), higher frequency of CD3⁺ CD4⁺ CD45RO⁺ CXCR3⁺ subsets (p < 0.05), higher frequency of CD14⁺ CD11C⁺ HLA-DR⁺ subset of dendritic cells (DCs) (p < 0.05), and a lower count of neutrophils (p < 0.05).
32779733	The COVID-19-associated perniosis exhibited vasocentric and eccrinotropic T-cell and monocyte-derived CD11c, CD14, and CD123+ dendritic cell infiltrates.
32918975	FACS at admission showed in PE patients elevated frequencies of CD3+CD8+ T cells among all CD3+ T-cells, and lower frequencies of Tregs and CD14+HLA-DR+-monocytes.
32925314	When compared to noncritically ill hospitalized COVID-19 patients, ICU patients with severe COVID-19 disease showed reduced mHLA-DR expression on circulating CD14+ monocytes at ICU admission, indicating a dysfunctional immune response.
32943497	Immune signatures were related to shifts in neutrophil to T cell ratio, elevated serum IL-6, MCP-1 and IP-10, and most strikingly, modulation of CD14+ monocyte phenotype and function. […] Modified features of CD14+ monocytes included poor induction of the prostaglandin-producing enzyme, COX-2, as well as enhanced expression of the cell cycle marker Ki-67.
33015591	Single-cell gene expression analysis of bronchoalveolar lavage fluids revealed a characteristic trajectory of PPARγ-related disturbance in the CD14+/CD16+ cells.
33040384	On more detailed analysis, these CD14+ CD16+ , FSC-high monocytes show features of mixed M1/M2 macrophage polarization with higher expression of CD80+ and CD206+ compared with the residual FSC-low monocytes and secretion of higher levels of IL-6, IL-10, and TNF-α, when compared with the normal controls.
33089452	HSCs and HPCs expand less effectively and have less functional colony forming capacity when grown with S protein, while peripheral blood monocytes upregulate CD14 expression and show distinct changes in size and granularity.
33178720	We hereby describe the possible novel severity biomarkers for COVID-19, CD11b+CD33+HLA-DR-CD14+ cells and CD11b+CD33+HLA-DR-CD66b+ cells.
33238863	Increased pro-inflammatory cytokines and CD14+CD16+ inflammatory monocytes, lymphopenia, and decreased levels of regulatory T cells are some of the immunological features that are seen in patients with SARS-CoV-2.
33264073	Decreased lymphocytes and increased CD14 + 4- monocytes are found in patients with severe COVID-19.
33362757	Monocytes were preserved in total number but displayed among them a subpopulation with a higher forward and side scatter properties, composed mainly of cells with a reduced expression of both CD14 and HLA-DR.