BRCA1 DNA repair associated

Gene Context Sentence

Table 2. Analysis of context sentence of BRCA1 gene in 4 abstracts.

PMID Gene Context Sentence
32591346 Using the 9 kDa protein SRP9 and the breast cancer oncogene BRCA1 as examples, we show how the proteome expression data can be used to refine the annotation of protein-coding regions of the African green monkey and the Vero cell line genomes.
32788235 Half of the patients with PSA50 had both MSI-H and pathogenic alterations in BRCA1 and BRCA2 in their G360 assays.
33186762 Next-generation sequencing of BRCA1, BRCA2, PALB2, RAD51C and RAD51D was performed. […] Of the 27 patients tested during the COVID-19 period, three carried a PV, two in BRCA1 and one in RAD51C. […] The clinical impact was immediate for the two BRCA1 BC cases undergoing neo-adjuvant chemotherapy, since double mastectomy and salpingo-oophorectomy will now be performed using two-step strategies.
33313973 Recently, our lab, part of a referral center in Italy, reported its experience regarding the execution of germline BRCA1/2 (gBRCA) testing during the first months of the coronavirus disease-2019 (COVID-19) pandemic, which highlights a substantial reduction (about 60%) compared with the first 2 months of the current year.