pleckstrin and Sec7 domain containing

ENTREZID: 5662 | Type: Protein Coding | Map: 10q24.32

OMIM: 217090 | 173350

Summary Entrez
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]