Gene Context Sentence
Table 2. Analysis of context sentence of PROS1 gene in 3 abstracts.
|PMID||Gene Context Sentence|
|32998369||The vitamin K-dependent factors protein S (PROS1) and growth-arrest-specific gene 6 (GAS6) and their tyrosine kinase receptors TYRO3, AXL, and MERTK, the TAM subfamily of receptor tyrosine kinases (RTK), are key regulators of inflammation and vascular response to damage. […] Because of these established biological functions, the GAS6-PROS1/TAM system is postulated to play an important role in SARS-CoV-2 infection and progression complications.|
|33254534||In it they expressed that hypercoagulation and immune hyper-reaction could occur secondary to decreased Protein S (PROS1). […] And hypoxia has been recently discovered to significantly decrease expression of PROS1.|
|33521069||Downstream analysis of unique DEGs of SARS-CoV-2 infection revealed changes in genes related to apoptosis (NRP1, FOXO1, TP53INP1, CSF2, and NLRP1), coagulation (F3, PROS1, ITGB3, and TFPI2), and vascular function (VAV3, TYMP, TCF4, and NR2F2), which may contribute to more systemic cardiovascular complications of COVID-19 than MERS and SARS.|