TET2


tet methylcytosine dioxygenase 2


ENTREZID: 54790 | Type: Protein Coding | Map: 4q24

OMIM: 614892 | 614162 | 613796 | 600555


Summary Entrez
The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]