ABO


ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase


Gene Context Sentence


Table 2. Analysis of context sentence of ABO gene in 13 abstracts.

PMID Gene Context Sentence
32293713 In order to evaluate the efficacy of convalescent plasma therapy in COVID-19 patients, we did this timely descriptive study. 6 laboratory confirmed COVID-19 patients were enrolled and received the transfusion of ABO-compatible convalescent plasma. […] The efficacy of this intervention was determined by the alleviation of symptoms, changes in radiologic abnormalities and laboratory tests.
32337859 He received a second KT from an ABO-incompatible donor 8 years ago.
32389803 We recorded higher 1-year rates of graft failure (hazard ratio [HR], 2.26; 95% confidence interval, 1.17 to 4.35; P = .01) and of 1-year overall mortality (HR, 3.13; 95% CI, 1.60 to 6.11; P = .0008) after transplantation of cryopreserved compared with noncryopreserved grafts, with adjustment for sex, performance score, comorbidity, cytomegalovirus serostatus, and ABO blood group match.
32400013 There has been growing concern about donor-derived transmissions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). […] Herein, we present the case of a patient who underwent ABO-incompatible living donor liver transplantation without knowing that the liver donor was infected with COVID-19 during the donation procedure.
32420611 We read with interest the recent report from Li and colleagues describing an association between ABO blood groups and risk of SARS-CoV-2 pneumonia [1]. […] Subsequently, in a larger validation cohort that included 2153 patients with COVID-19, this ABO effect was reproduced with blood group O again being associated with a significant protective effect (p < 0.001).
32423094 Data from the World Health Organization (WHO) and Chinese scientists show that of all cases about 1.7% of women who contract the virus will die compared with 2.8% of men, and data from Hong Kong hospitals state that 32% of male and 15% of female COVID-19 patients required intensive care or died. […] Other genes, out from the RAS-pathway, might directly or indirectly impact on the ACE1/ACE2 balance by influencing its main actors (e.g., ABO locus, SRY, SOX3, ADAM17).
32453863 Juyi Li et al. [1] have recently published “an association between ABO blood groups and risk of SARS-CoV-2 pneumonia”, an observation already reported a few weeks ago as a MedRxiv preprint by Jiao Zhao et al. [2] and which had a certain impact in the press.
32516462 I read with interest the recent article by Li et al (1) detailing the risk for COVID-19 pneumonia and ABO blood group.
32525844 Thus, we analyzed key safety metrics after transfusion of ABO compatible human COVID-19 convalescent plasma in 5,000 hospitalized adults with severe or life threatening COVID-19, with 66% in the intensive care unit, as part of the US FDA Expanded Access Program for COVID-19 convalescent plasma.
32558485 The association signal at locus 9q34.2 coincided with the ABO blood group locus; in this cohort, a blood-group-specific analysis showed a higher risk in blood group A than in other blood groups (odds ratio, 1.45; 95% CI, 1.20 to 1.75; P = 1.48×10-4) and a protective effect in blood group O as compared with other blood groups (odds ratio, 0.65; 95% CI, 0.53 to 0.79; P = 1.06×10-5). […] We identified a 3p21.31 gene cluster as a genetic susceptibility locus in patients with Covid-19 with respiratory failure and confirmed a potential involvement of the ABO blood-group system.
32562665 To explore ABO blood group distribution and clinical characteristics in patients with COVID-19. […] The differences in the ABO blood group distribution between COVID-19 patients and the control group (1991 cases) were analyzed. […] The ABO blood group distribution was related to COVID-19 status. […] Patients with blood group A had an increased risk for infection with SARS-CoV-2, whereas blood group O was associated with a decreased risk, indicating that certain ABO blood groups were correlated with SARS-CoV-2 susceptibility.
32573724 To comprehensively evaluate the effectiveness, safety, and indications of convalescent plasma transfusion (CPT) therapy for severe or critical COVID-19 patients, we analyzed the clinical, laboratory, and radiologic characteristics of 1,568 patients from a single center, in which 138 patients received ABO-compatible CPT.
32593060 In testing, ABO compatibility is assessed after classifying donors into the four blood types, namely, A, B, AB and O, to indicate the suitability and safety of plasma for administration in order to refine the CP tested list repository.