MTHFR, MTHFR
phosphoribosylformylglycinamidine synthase
Gene Expression
Table 1. PFAS expression overview from human protein atlas database.
| ENSEMBL | Tissue | Protein | mRNA |
|---|---|---|---|
| ENSG00000178921 | appendix | High | 16.0 |
| ENSG00000178921 | tonsil | High | 13.5 |
| ENSG00000178921 | urinary bladder | High | 9.4 |
| ENSG00000178921 | bone marrow | Low | 8.7 |
| ENSG00000178921 | caudate | Low | NA |
| ENSG00000178921 | cerebral cortex | Low | 13.0 |
| ENSG00000178921 | colon | Low | 9.1 |
| ENSG00000178921 | duodenum | Low | 7.1 |
| ENSG00000178921 | epididymis | Low | 4.1 |
| ENSG00000178921 | heart muscle | Low | 2.8 |
| ENSG00000178921 | hippocampus | Low | NA |
| ENSG00000178921 | liver | Low | 2.1 |
| ENSG00000178921 | lung | Low | 7.6 |
| ENSG00000178921 | lymph node | Low | 17.2 |
| ENSG00000178921 | ovary | Low | 8.5 |
| ENSG00000178921 | skeletal muscle | Low | 2.4 |
| ENSG00000178921 | skin | Low | 10.4 |
| ENSG00000178921 | small intestine | Low | 8.3 |
| ENSG00000178921 | thyroid gland | Low | 9.9 |
| ENSG00000178921 | tonsil | Low | 13.5 |
| ENSG00000178921 | adrenal gland | Medium | 8.0 |
| ENSG00000178921 | appendix | Medium | 16.0 |
| ENSG00000178921 | breast | Medium | 7.3 |
| ENSG00000178921 | caudate | Medium | NA |
| ENSG00000178921 | cerebellum | Medium | NA |
| ENSG00000178921 | cerebral cortex | Medium | 13.0 |
| ENSG00000178921 | endometrium | Medium | 12.6 |
| ENSG00000178921 | fallopian tube | Medium | 12.2 |
| ENSG00000178921 | gallbladder | Medium | 5.9 |
| ENSG00000178921 | kidney | Medium | 6.1 |
| ENSG00000178921 | lymph node | Medium | 17.2 |
| ENSG00000178921 | ovary | Medium | 8.5 |
| ENSG00000178921 | pancreas | Medium | 1.6 |
| ENSG00000178921 | parathyroid gland | Medium | 10.6 |
| ENSG00000178921 | placenta | Medium | 9.2 |
| ENSG00000178921 | prostate | Medium | 10.1 |
| ENSG00000178921 | rectum | Medium | 9.0 |
| ENSG00000178921 | seminal vesicle | Medium | 8.0 |
| ENSG00000178921 | spleen | Medium | 14.7 |
| ENSG00000178921 | stomach | Medium | 6.2 |
| ENSG00000178921 | testis | Medium | 13.6 |
| ENSG00000178921 | tonsil | Medium | 13.5 |
| ENSG00000178921 | adipose tissue | Not detected | 8.4 |
| ENSG00000178921 | breast | Not detected | 7.3 |
| ENSG00000178921 | cerebral cortex | Not detected | 13.0 |
| ENSG00000178921 | cervix, uterine | Not detected | 9.3 |
| ENSG00000178921 | colon | Not detected | 9.1 |
| ENSG00000178921 | endometrium | Not detected | 12.6 |
| ENSG00000178921 | esophagus | Not detected | 6.1 |
| ENSG00000178921 | kidney | Not detected | 6.1 |
| ENSG00000178921 | lung | Not detected | 7.6 |
| ENSG00000178921 | placenta | Not detected | 9.2 |
| ENSG00000178921 | salivary gland | Not detected | 3.6 |
| ENSG00000178921 | skin | Not detected | 10.4 |
| ENSG00000178921 | smooth muscle | Not detected | 12.4 |
| ENSG00000178921 | spleen | Not detected | 14.7 |