OAT

ornithine aminotransferase

Gene Context Sentence


Table 2. Analysis of context sentence of OAT gene in 8 abstracts.

PMID Gene Context Sentence
32633418 This study aimed to investigate whether the use of oral antithrombotic therapy (OAT) was associated with a lower mortality in NH residents with COVID-19. […] The association between age, sex, comorbidity, OAT, and mortality was assessed using logistic regression analysis. […] OAT was associated with a lower mortality in NH residents with COVID-19 in the univariable analysis (odds ratio (OR) = 0.89; 95% confidence interval (CI) = 0.41-1.95). […] We did not find evidence for any protection against mortality by OAT, necessitating further research into strategies to mitigate poor outcome of COVID-19 in vulnerable NH populations.
32680520 Increasing access to safe and effective opioid agonist treatment (OAT) and other harm reduction services during this pandemic is critical to reduce risk. […] In response to COVID-19, healthcare is increasingly being delivered by telephone and video consultation, and this report describes the development of a national model of remote care to eliminate waiting lists and increase access to OAT in Ireland. […] The purpose of this initiative is to provide easy access to OAT by developing a model of remote assessment and ongoing care and eliminate existing national waiting lists. […] The Irish College of General Practitioners in conjunction with the National Health Service Executive office for Social Inclusion agreed a set of protocols to enable a system of remote consultation but still delivering OAT locally to people who use drugs. […] This model was targeted at OAT services with existing waiting lists due to a shortage of specialist medical staff. […] The development of a remote model of healthcare delivery allows for the reduction in transmission risks associated with COVID-19, increases access to OAT, reduces waiting times and minimises barriers to services. […] Fast adaptation of OAT delivery is critical to ensure access to and continuity of service delivery and minimise risk to our staff, patients and community.
32868681 To describe how the novel coronavirus (COVID-19) pandemic has affected opioid agonist treatment (OAT) programs in jails and prisons. […] Ten out of 16 systems reported downsizing their OAT programs. […] In 13 out of 16 systems some OAT program participants were released early due to COVID-19 infection risk. […] Jails and prisons with existing OAT programs have curtailed their operations in the context of the COVID-19 pandemic. […] Given the robust evidence base around OAT for treating opioid use disorder and averting overdose deaths, guidance is needed on maintaining and ramping up medication access as carceral facilities grapple with implementing COVID-19 mitigation.
32870435 The results showed that wheat-derived alpha/beta-gliadin, oat-derived avenin, and ribulose bisphosphate carboxylase small chain of different origin could be good protein source in generating potent binders to SARS-CoV-2 spike RBD.
33191004 On March 16, 2020, Ukraine’s Ministry of Health issued nonspecific interim guidance to continue enrolling patients in opioid agonist therapies (OAT) and transition existing patients to take-home dosing to reduce community COVID-19 transmission. […] Though the number of OAT patients increased modestly, the proportion receiving take-home dosing increased from 57.5% to 82.2%, which translates on average to 963,952 fewer clinic interactions annually (range: 728,652-1,016,895) and potentially 80,329 (range: 60,721-84,741) fewer hours of in-person clinical encounters. […] OAT delivery has improved and become more efficient, but clinicians should plan long-term should COVID-19 return in the near future. […] If the new efficiencies are maintained, it will free the workforce to further scale up OAT.
33277286 Opioid agonist treatment (OAT) can be effective in reducing illicit opioid use and fatal overdose, and improving multiple health and social outcomes. […] Despite evidence for its effectiveness, there are significant deficits in OAT globally. […] Telemedicine is not used routinely in OAT, and little is known about the current levels of use and effectiveness. […] To be included, studies must report on remote ways of providing OAT (including assessment, induction and monitoring) or related psychosocial support; be published in English after 2010. […] The results of this scoping review will inform the development of a national remote model of OAT.
33325311 Data from a 16-week outpatient randomised controlled trial (RCT) of 141 adults with opioid use disorder (OUD) receiving Opioid Assisted Treatment (OAT) using buprenorphine/naloxone film (BUP/NX-F) was, used to examine the association between family engagement in and opioid use and rate of retention in treatment. […] Family engagement in treatment is an independent predictor of retention in treatment but not opioid use in adults receiving OAT.
33385974 Individuals in opioid agonist treatment (OAT) are uniquely challenged because of disruption to treatment, medication diversion, and isolation during the pandemic. […] The use of fentanyl increased by 108% among OAT patients in Ontario during the COVID 19 pandemic. […] We argue that the persistent increase of fentanyl exposure over time, specifically in the OAT population, suggests that reduced monitoring may decrease OAT’s effectiveness and negatively impact patient outcomes.