MUC1
mucin 1, cell surface associated
Gene Context Sentence
Table 2. Analysis of context sentence of MUC1 gene in 5 abstracts.
| PMID | Gene Context Sentence |
|---|---|
| 33098359 | A series of increased extracellular factors including Tenascin-C (TNC), Mucin-1 (KL-6 or MUC1), Lipocalin-2 (LCN2), periostin (POSTN), Chitinase 3-like 1 (CHI3L1 or YKL40), and S100A12, and the antigens including lymphocyte antigen 6D/E48 antigen (LY6D), CD9 antigen, CD177 antigen, and prostate stem cell antigen (PSCA) were identified, among which the proinflammatory factors TNC and KL-6 were further validated in serum of another thirty-nine COVID-19 patients and healthy controls, showing high potentials of being biomarkers or therapeutic candidates for COVID-19. |
| 33184103 | MUC1, MUC4, and MUC16 are the three major transmembrane mucins of the respiratory tracts which prevent microbial invasion, can act as releasable decoy receptors, and activate intracellular signal transduction pathways. |
| 33225317 | suggests that the FDA-approved SYK inhibitor fostamatinib inhibits MUC1 in the respiratory tract and has the potential to treat serious outcomes of coronavirus COVID-19, including acute respiratory distress syndrome (ARDS) and acute lung injury (ALI). |
| 33294858 | , SYK inhibition by the active metabolite R406 promotes MUC1 removal from the cell surface. |
| 33327522 | The increased synthesis of MUC1 was also confirmed by immunostaining. |