CXCL10


C-X-C motif chemokine ligand 10


ENTREZID: 3627 | Type: Protein Coding | Map: 4q21.1

OMIM: 147310


Summary Entrez
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the ‘cytokine storm’ immune response to SARS-CoV-2 infection. [provided by RefSeq, Sep 2020]