GRN
granulin precursor
Gene Context Sentence
Table 2. Analysis of context sentence of GRN gene in 1 abstracts.
| PMID | Gene Context Sentence |
|---|---|
| 33249471 | In contrast, we observed a specific upregulation of the immunomodulatory protein progranulin (GRN). […] High GRN abundance was associated with adverse outcomes and increased expression of interleukin-6 in COVID-19. […] The data from this registry reveals that GRN is specifically upregulated in SARS-CoV-2 positive patients while interleukin-6 may serve as marker for disease severity. […] The potential of GRN as a biomarker and a possible impact of increased GRN expression on interferon signaling, virus elimination, and virus-induced lung tissue damage in COVID-19 should be further explored. |