SAMHD1

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1

ENTREZID: 25939 | Type: NA | Map: 20q11.23

OMIM: 300335


Summary Entrez
This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]