BRD4


bromodomain containing 4


ENTREZID: 23476 | Type: Protein Coding | Map: 19p13.12

OMIM: 613347 | 613029 | 612555 | 605724 | 600185 | 194070 | 176807 | 155255 | 114480


Summary Entrez
The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]