angiotensin II receptor type 2
Gene Context Sentence
Table 2. Analysis of context sentence of AGTR2 gene in 3 abstracts.
|PMID||Gene Context Sentence|
|32589459||Other receptors such as ANPEP, AGTR2 are expressed at low level in the conjunctiva.|
|32750889||Here we found that AGTR2 (angiotensin II receptor type 2), a G-protein coupled receptor, has interaction with ACE2 and is highly expressed in lung with a high tissue specificity. […] More importantly, simulation of 3D structure based protein-protein interaction reveals that AGTR2 shows a higher binding affinity with the Spike protein of SARS-CoV-2 than ACE2 (energy: -8.2 vs. -5.1 [kcal/mol]). […] A number of compounds, biologics and traditional Chinese medicine that could decrease the expression level of AGTR2 were predicted. […] Finally, we suggest that AGTR2 could be a putative novel gene for the the entry of SARS-CoV-2 into human cells, which could provide different insight for the research of SARS-COV-2 proteins with their receptors.|
|33059811||Whole transcriptome resequencing was used to measure the mRNA expression of AGT, ACE, ACE2, Renin, Agtr1a, Agtr1b, Agtr2, and Mas1 in mouse lung tissue. […] Agtr2 expression gradually decreased to a low level after birth.|