Gene Context Sentence

Table 2. Analysis of context sentence of EMB gene in 4 abstracts.

PMID Gene Context Sentence
32529795 Since December 2019, the novel coronavirus SARS-CoV-2 has spread rapidly throughout China and keeps the world in suspense. […] Cardiovascular complications with myocarditis and embolism due to COVID-19 have been reported. […] Endomyocardial biopsies (EMBs) of 104 patients (mean age: 57.90 ± 16.37 years; left ventricular ejection fraction: 33.7 ± 14.6%, sex: n = 79 male/25 female) with suspected myocarditis or unexplained heart failure were analysed. […] EMB analysis included histology, immunohistochemistry, and detection of SARS-CoV-2 genomes by real-time reverse transcription polymerase chain reaction in the IKDT Berlin, Germany. […] Among 104 EMBs investigated, five were confirmed with SARS-CoV-2 infected by reverse real-time transcriptase polymerase chain reaction. […] Additionally, we investigated histopathological changes in myocardial tissue showing that the inflammatory process in EMBs seemed to permeate vascular wall leading to small arterial obliteration and damage. […] This is the first report that established the evidence of SARS-CoV-2 genomes detection in EMBs. […] EMB-based identification of the cause of myocardial injury may contribute to explain the different evolution of complicated SARS-CoV-2-infection and to design future specific and personalized treatment strategies.
33225579 At the first endomyocardial biopsy (EMB)-proven episode, she had concomitant pneumonia, and a temporary biventricular assist device implant was followed by complete and long-lasting cardiac recovery. […] Despite negative seriate nasopharyngeal swabs and EMB during hospitalization, an antibody positivity for severe acute respiratory syndrome coronavirus 2 was discovered after 4 weeks from discharge. […] This is the first report of an EMB-proven, immune-mediated (virus-negative) recurrence of fulminant myocarditis.
33299786 COVID 19 so far is not a known cardiotropic virus, and the term “myocarditis” should be exclusively used after EMB or autopsy proven diagnosis.
33594347 The aetiology is often viral and endomyocardial biopsy (EMB) is the gold standard for definite myocarditis. […] EMB was performed but could neither identify the virus in the cardiomyocytes, nor signs of inflammation.