OS9

OS9 endoplasmic reticulum lectin

ENTREZID: 10956 | Type: NA | Map: 12q13.3-q14.1

OMIM: 300335


Summary Entrez
This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]