MERTK


MER proto-oncogene, tyrosine kinase


ENTREZID: 10461 | Type: Protein Coding | Map: 2q13

OMIM: 618872 | 611318


Summary Entrez
This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008]