ZOLEDRONIC


DrugCentral: zoledronic
Synonymous : None



Drug Sentece Context


Table 1. Analysis of context sentence of zoledronic gene in 2 abstracts.

pmid sentence
32396134 IV zoledronic acid infusions can be delayed for 6-9 months during the pandemic.
32600410 Amino-bisphosphonates such as zoledronic acid (ZA) can possibly ameliorate or prevent severe COVID-19 disease by at least three distinct mechanisms: (1) as immunostimulants which could boost γδ T cell expansion, important in the acute response in the lung; (2) as DC modulators, limiting their ability to only partially activate T cells; and (3) as prenylation inhibitors of small GTPases in the endosomal pathway of the DC to prevent expulsion of lysosomes containing SARS-CoV-2 virions.