XANTHINE
DrugBank ID: db02134
DrugCentral: xanthine
Synonymous : None
Drug Sentece Context
Table 1. Analysis of context sentence of xanthine gene in 7 abstracts.
| pmid | sentence |
|---|---|
| 32473070 | Pentoxifylline is a methyl-xanthine and it inhibits phosphodiesterase IV (PDE IV). |
| 32536670 | Favipiravir is metabolized to an inactive metabolite M1 by aldehyde oxidase and xanthine oxidase, and excreted into urine. |
| 32787748 | Pentoxifylline is an inhibitor of TNF-α production and oxypurinol inhibits xanthine oxidase. |
| 32840387 | In MA-induced OA rat, the tumor necrosis factor alpha, interleukin 6, C-reactive protein, rheumatoid factors, reactive oxygen species, as well as all the mitochondrial markers such as mitochondria membrane potential, swelling mitochondria, cytochrome c oxidase (complex IV), and serum oxidative/antioxidant status (malondialdehyde level and activities of myeloperoxidase and xanthine oxidase) are elevated. |
| 33129363 | • Clinical prognostic non-survival, palliative care, or in deep coma and no have response to supportive treatment within three hours of admission • Patient with irregular rhythm • Patient with a history of heart attack (myocardial infarction) • Patient with a family history of sudden death from heart attack before the age of 50 • Take other drugs that can cause prolonged QT interval • Patient who is receiving immunosuppressive therapy (cyclosporin) which cannot be switched to another agent or adjusted while using the investigational drug • Gout/history of Gout or hyperuricemia (above the ULN), hereditary xanthinuria or xanthine calculi of the urinary tract. |