DrugBank ID: db11298
DrugCentral: thioredoxin
Synonymous : None

Drug Sentece Context

Table 1. Analysis of context sentence of thioredoxin gene in 1 abstracts.

pmid sentence
32984400 Using web-based protease cleavage site prediction tools, we show that Mpro may be targeting not only GPX1, but several other selenoproteins including SELENOF and thioredoxin reductase 1, as well as glutamate-cysteine ligase, the rate-limiting enzyme for glutathione synthesis. […] This hypothesized proteolytic knockdown of components of both the thioredoxin and glutaredoxin systems is consistent with a viral strategy to inhibit DNA synthesis, to increase the pool of ribonucleotides for RNA synthesis, thereby enhancing virion production.