TEPROTUMUMAB
DrugBank ID: db06343
DrugCentral: teprotumumab
Synonymous :immunoglobulin g1, anti-(human insulin-like growth factor i receptor) (human monoclonal heavy chain), disulfide with human monoclonal light chain, dimer | teprotumumab-trbw
Drug Sentece Context
Table 1. Analysis of context sentence of teprotumumab gene in 1 abstracts.
| pmid | sentence |
|---|---|
| 32795835 | Teprotumumab is a monoclonal antibody directed against the IGF-1R that was FDA-approved in 2020 for the treatment of Graves’ orbitopathy. […] In order to determine if teprotumumab may reduce lung injury and death related to ARDS in the setting of COVID-19, preliminary clinical data is needed. […] Once these are ascertained, and if the data support IGF-1 involvement, a randomized, placebo-controlled phase 2A trial of teprotumumab therapy in the setting of COVID-19-related ARDS and non-COVID-19-related ARDS designed to generate initial data on short-term efficacy, safety, dosing and administration should be performed. |