TEICOPLANIN


DrugBank ID: db06149
DrugCentral: teicoplanin
Synonymous :teichomycin a2 | teicoplanin | teicoplanina | téicoplanine | teicoplaninum



Drug Sentece Context


Table 1. Analysis of context sentence of teicoplanin gene in 6 abstracts.

pmid sentence
32179150 Teicoplanin, an antibiotic used to treat staphylococcal infections, previously showed efficacy to inhibit the first stage of the Middle East respiratory syndrome coronavirus (MERS-CoV) viral life cycle in human cells. […] This activity is conserved against SARS-Cov-2, thus placing teicoplanin as a potential treatment for patients with this virus.
32307245 The roles of teicoplanin (which inhibits the viral genome exposure in cytoplasm) and monoclonal and polyclonal antibodies in the treatment of SARS-CoV-2 are under investigation.
32394467 Cathepsin L is required for entry of the 2019-nCoV virus into the cell as target teicoplanin inhibits virus replication.
32400323 Although in vitro studies are scarce, data regarding chloroquine and hydroxychloroquine, remdesivir, nitazoxanide, teicoplanin, ivermectin, lopinavir, homoharringtonine and emetine seem promising.
32419524 To obtain convincing recommendations, we referred to opinions from the US National Institute of Health regarding drugs repurposed for COVID-19 therapy.Expert opinion: Although strong evidence of well-designed randomized controlled studies regarding COVID-19 therapy is presently lacking, remdesivir, teicoplanin, hydroxychloroquine (not in combination with azithromycin), and ivermectin might be effective antiviral drugs and are deemed promising candidates for controlling SARS-CoV-2.
32522754 A rapid recovery of respiratory and general symptoms was observed after 1 week of treatment with lopinavir/ritonavir plus hydroxychloroquine and broad-spectrum antibiotics (piperacillin-tazobactam plus teicoplanin).