SULODEXIDE
DrugBank ID: db06271
DrugCentral: sulodexide
Synonymous :sulodexida
Drug Sentece Context
Table 1. Analysis of context sentence of sulodexide gene in 7 abstracts.
| pmid | sentence |
|---|---|
| 33030036 | Sulodexide represents a mixture of fast-moving heparin (FMH) and dermatan sulfate (DS) and has been used for the management of venous diseases such as DVT and related disorders. […] The purpose of this study is to compare sulodexide and its components with unfractionated heparin (UFH) to determine its suitability for the indications in which UFH is used. […] Active pharmaceutical ingredients (API) versions of sulodexide, FMH and DS were obtained from Alfasigma. […] In the clot based (PiCT, aPTT and TT), anti-Xa and IIa assays, both the UFH and FMH produced stronger activities in these assays followed by sulodexide. […] Sulodexide was slightly weaker in this assay, whereas DS produced relatively weaker effects. […] In comparison to sulodexide, both UFH and FMH exhibit comparable anticoagulant activity despite differences in their molecular weight. […] These results suggest that sulodexide can be developed as a parenteral anticoagulant for indications in which UFH is used. |