DrugBank ID: db00649
Synonymous :1-(2,3-dideoxy-beta-d-glycero-pent-2-enofuranosyl)thymine | 2’,3’-didehydro-3’-deoxythimidine | 3’-deoxy-2’-thymidinene | estavudina | sanilvudine | stavudin | stavudine | stavudinum | stv
Drug Sentece Context
Table 1. Analysis of context sentence of stavudine gene in 2 abstracts.
|32562705||While all 11 molecules tested displayed incorporation, 6 exhibited immediate termination of the polymerase reaction (triphosphates of Carbovir, Ganciclovir, Stavudine and Entecavir; 3’-OMe-UTP and Biotin-16-dUTP), 2 showed delayed termination (Cidofovir diphosphate and 2’-OMe-UTP), and 3 did not terminate the polymerase reaction (2’-F-dUTP, 2’-NH2-dUTP and Desthiobiotin-16-UTP). […] Prodrugs of five of these nucleotide analogues (Cidofovir, Abacavir, Valganciclovir/Ganciclovir, Stavudine and Entecavir) are FDA-approved medications for treatment of other viral infections, and their safety profiles are well established.|