SPERMIDINE
DrugBank ID: db03566
DrugCentral: spermidine
Synonymous :1,5,10-triazadecane | 4-azaoctamethylenediamine | 4-azaoctane-1,8-diamine | n-(3-aminopropyl)-1,4-butane-diamine | n-(3-aminopropyl)butane-1,4-diamine | spermidin | spermidine
Drug Sentece Context
Table 1. Analysis of context sentence of spermidine gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 33317695 | We demonstrate that levels of the endogenous autophagy-inducing metabolite spermidine fall in human T cells with age. […] Spermidine supplementation in T cells from old donors recovers their autophagy level and function, similar to young donors’ cells, in which spermidine biosynthesis has been inhibited. […] Finally, our data show that endogenous spermidine maintains autophagy via the translation factor eIF5A and transcription factor TFEB. |
| 33494530 | In this study, we investigated the polyglucin:spermidine conjugate as a carrier of an mRNA-RBD vaccine encoding the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. […] Our results showed that the proposed polycationic polyglucin:spermidine conjugate can be considered a promising and safe means to the delivery of mRNA vaccines, in particular mRNA vaccines against SARS-CoV-2. |