SINEFUNGIN


DrugBank ID: db01910
DrugCentral: sinefungin
Synonymous :(2s,5s)-2,5-diamino-6-[(2r,3s,r,5r)-5-(6-amino-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]hexanoic acid | 6,9-diamino-1-(6-amino-9h-purin-9-yl)-1,5,6,7,8,9-hexadeoxy-beta-d-ribo-decofuranuronic acid | 6,9-diamino-1-(6-amino-9h-purin-9-yl)-1,5,6,7,8,9-hexadeoxydecofuranuronic acid | adenosyl-ornithine | sinefungin | sinefungina | sinefungine | sinefunginum



Drug Sentece Context


Table 1. Analysis of context sentence of sinefungin gene in 4 abstracts.

pmid sentence
32379896 Our theoretical models suggest several drugs, such as carfilzomib, sinefungin, tecadenoson, and trabodenoson, that could be further investigated for their potential for treating COVID-19.
32563813 The most active nsp14 inhibitor identified is as potent as but particularly more specific than the broad-spectrum MTase inhibitor, sinefungin.
32573355 First, drug shape-based screening (among FDA approved drugs) with a known template of MTase inhibitor, sinefungin was done and best compounds with high similarity scores were selected. […] The results showed that Raltegravir and Maraviroc among other compounds can bind strongly to the active site of the protein compared to sinefungin, and can be potential candidates to inhibit NSP-16. […] Also, the MD simulation results suggested that the Maraviroc and Raltegravir are more effective drug candidates than Sinefungin for inhibiting the enzyme.