SEROTONIN

Drug Sentece Context

Table 1. Analysis of context sentence of serotonin gene in 15 abstracts.

pmid	sentence
32314850	Acetyl-CoA is a necessary cosubstrate for arylalkylamine N-acetyltransferase, providing an acetyl group to serotonin, and thereby initiating the melatonergic pathway.
32535509	INFs are known to shift the metabolism of tryptophan (TRP) away from its role as a precursor of serotonin. […] Selective serotonin reuptake inhibitors may also be tried if the depressive symptomatology is not short-lived.
32685905	The serotonin release assay confirmed HIT in 1 case, and 2 cases were negative.
32720827	The serotonin release assay eventually returned positive, which confirmed the diagnosis of HIT.
32768893	We propose using a class of antidepressants named selective serotonin reuptake inhibitors for their reported potential antiviral effect, modulatory effect of respiratory symptoms, antioxidant properties and immunoregulatory effects beside their main action as antidepressant. […] In addition, the low cost of selective serotonin reuptake inhibitors might add a benefit for coronavirus disease patients.
32811575	Results from the Imperial College London Psilodep-RCT comparing the efficacy and mechanisms of action of psilocybin therapy to the selective serotonin reuptake inhibitor (SSRI) escitalopram will soon be published.
32838110	We agree that false-positive enzyme immunoassay (EIA) detection of anti-platelet factor 4 (PF4)/heparin antibodies could explain the results we observed in patients #2 and #3 (2), and this has been the conventional interpretation when functional testing (such as the serotonin-release assay [SRA]) returns negative.
32933552	Use of warfarin, selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), diuretics, corticosteroids, and antiarrhythmic drugs.
32957797	DDC is a crucial enzyme that participates in the synthesis of both dopamine and serotonin. […] SARS-CoV2-induced downregulation of ACE2 expression might reduce dopamine and serotonin synthesis, causing hypodopaminergia.
33022271	In addition to its classical role as a neurotransmitter, serotonin (5-hydroxytryptamine, 5-HT) has immunomodulatory properties, downregulating the inflammatory response by central and peripheral mechanisms. […] In this review, we describe the roles of 5-HT in the regulation of systemic inflammation and the potential benefits of the use of specific serotonin reuptake inhibitors as a coadjutant therapy to attenuate neurological complications of COVID-19.
33036662	Use of warfarin, selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), diuretics, corticosteroids, and antiarrhythmic drugs 3.
33041811	Predictors of mortality were older age (P = 0.001), antecedents of cerebrovascular disorders (P = 0.034), previous use of oral anticoagulants (P = 0.009) or selective serotonin reuptake inhibitors (P = 0.003), and increased levels of interleukin-6 (P = 0.001).