SELINEXOR
DrugBank ID: db11942
DrugCentral: selinexor
Synonymous :selinexor
Drug Sentece Context
Table 1. Analysis of context sentence of selinexor gene in 5 abstracts.
| pmid | sentence |
|---|---|
| 32549297 | This review also reports the rationale for a possible use of drugs commonly employed in neoplastic therapy, such as bevacizumab, ibrutinib, selinexor, thalidomide, carfilzomib, and PD-1 inhibitors, for the treatment of SARS-CoV-2 infection. |
| 32569833 | Clinical studies using the XPO1 inhibitor selinexor as a therapy for COVID-19 infection are in progress. |
| 33079180 | Leronlimab, a monoclonal antibody blocker of CCR5 originally developed to treat HIV-1 infection, was administered as an open label compassionate use therapeutic for COVID-19. 23 hospitalized severe/critical COVID-19 patients received 700mg leronlimab subcutaneously, repeated after seven days in 17/23 patients still hospitalized. 18/23 received other experimental treatments, including convalescent plasma, hydroxychloroquine, steroids, and/or tocilizumab. 5/23 received leronlimab after blinded placebo-controlled trials of remdesivir, sarilumab, selinexor, or tocilizumab. |
| 33097472 | Simulated treatment with remdesivir, selinexor, neutralizing antibodies, or cellular immunotherapy demonstrates that rapid viral elimination is possible if in vivo potency is sufficiently high. |