DrugBank ID: db00020
Synonymous :recombinant human granulocyte-macrophage colony stimulating factor | rgm-csf | rhu gm-csf | sargramostim
Drug Sentece Context
Table 1. Analysis of context sentence of sargramostim gene in 5 abstracts.
|32503663||Sargramostim is a man-made form of the naturally-occurring protein GM-CSF. […] Inhaled sargramostim 125 μg twice daily for 5 days in addition to standard care. […] Upon progression of disease requiring mechanical ventilation or to acute respiratory distress syndrome (ARDS) and initiation of mechanical ventilator support within the 5 day period, inhaled sargramostim will be replaced by intravenous sargramostim 125 μg/m2 body surface area once daily until the 5 day period is reached. […] From day 6 onwards, progressive patients in the active group will have the option to receive an additional 5 days of IV sargramostim, based on the treating physician’s assessment. […] Subjects progressing to ARDS and requiring invasive mechanical ventilatory support, from day 6 onwards in the standard of care group will have the option (clinician’s decision) to initiate IV sargramostim 125m μg/m2 body surface area once daily for 5 days.|
|33173052||Drug enrichment analysis of dysregulated genes has allowed us to propose novel therapies, including lung surfactants, respiratory stimulants, sargramostim, and oseltamivir.|