RUPATADINE
DrugBank ID: db11614
DrugCentral: rupatadine
Synonymous :rupatadina | rupatadine
Drug Sentece Context
Table 1. Analysis of context sentence of rupatadine gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 32883529 | The histamine1 receptor antagonist rupatadine was developed to have anti-PAF activity and inhibits activation of human mast cells in response to PAF. […] Rupatadine could be repurposed for COVID-19 prophylaxis. |
| 33023287 | PureLut® or FibroProtek®) together with the antihistamine rupatadine, which also has anti-platelet activating factor (PAF) activity and inhibits mast cells that have been implicated in the pathogenesis of cytokine storms in COVID-19. |
| 33296106 | The histamine-1 receptor antagonist rupatadine was developed to have anti-PAF activity, and also inhibits activation of human mast cells in response to PAF. […] Rupatadine could be repurposed for COVID-19 prophylaxis alone or together with other PAF-inhibitors of natural origin such as the flavonoids quercetin and luteolin, which have antiviral, anti-inflammatory, and anti-PAF actions. |