RIFABUTIN
DrugBank ID: db00615
DrugCentral: rifabutin
Synonymous :1,4-dihydro-1-deoxy-1’,4-didehydro-5’-(2-methylpropyl)-1-oxorifamycin xiv | 4-deoxo-3,4-(2-spiro(n-isobutyl-4-piperidyl)-2,5-dihydro-1h-imidazo)-rifamycin s | 4-n-isobutylspiropiperidylrifamycin s | ansamicin | ansamycin | rifabutin | rifabutina | rifabutine | rifabutinum
Drug Sentece Context
Table 1. Analysis of context sentence of rifabutin gene in 1 abstracts.
| pmid | sentence |
|---|---|
| 32873176 | The aim of the present study is to identify the conservation level of nsp12 motifs (A-G), using consurf server, and discover their interactions with rifabutin, rifampicin, rifapentin, sorangicin A, streptolydigin, myxopyronin B, VXR and VRX using AutoDockTools-1.5.6, Gromacs 2018.2 and g-mmpbsa. […] The binding energies of streptolydigin, VXR, rifabutin, rifapentine, VRX, sorangicin A, myxopyronin B and rifampicin with nsp12 protein are -8.11, -8.23, -7.14, -6.94, -6.55, -5.46, -5.33 and -5.26 kcal/mol, respectively. |
| 32950529 | This study revealed that Rifabutin, Rifapentine, Fidaxomicin, 7-methyl-guanosine-5’-triphosphate-5’-guanosine and Ivermectin have a potential inhibitory interaction with RdRp of SARS-CoV-2 and could be effective drugs for COVID-19. |