RAMIPRIL
DrugBank ID: db00178
DrugCentral: ramipril
Synonymous :(2s-(1(r(r)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid | ramipril | ramiprilum
Drug Sentece Context
Table 1. Analysis of context sentence of ramipril gene in 2 abstracts.
| pmid | sentence |
|---|---|
| 32470515 | RASTAVI (NCT03201185) is an ongoing randomized clinical trial randomly allocating Ramipril or control after successful transcatheter aortic valve replacement at 14 centers is Spain. […] As in April 1st 2020, 102 patients (50 Ramipril and 52 controls) were included in the trial. […] Median time of Ramipril treatment was 6 months [IQR:2.9-11.4]. […] Eleven patients (10.8%) have been diagnosed with COVID-19 (6 in control group and 5 receiving Ramipril, HR=1.150 [95%CI: 0.351-3.768]). […] Admission and oxygen supply was required in 4.9% (2 patients in the Ramipril and 3 in control), and 4 of them died (two in each randomized group). […] In a high risk population of old patients with cardiovascular disease, randomization to Ramipril had no impact in the incidence or severity of COVID-19. |
| 32752951 | The results obtained from this study showed that Ramipril, Delapril and Lisinopril could bind with ACE2 receptor and [SARS-CoV-2/ACE2] complex better than chloroquine and hydroxychloroquine. |
| 33310740 | In healthy young mice, neither the ACE inhibitor ramipril nor the AT1 receptor blocker telmisartan affected lung or kidney ACE2 or TMPRSS2, except for a small increase in kidney ACE2 protein with ramipril. |