QUINACRINE
DrugBank ID: db01103
DrugCentral: quinacrine
Synonymous :2-methoxy-6-chloro-9-diethylaminopentylaminoacridine | 3-chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine | 6-chloro-9-((4-(diethylamino)-1-methylbutyl)amino)-2-methoxyacridine | mepacrine | n4-(6-chloro-2-methoxy-9-acridinyl)-n1,n1-diethyl-1,4-pentanediamine
Drug Sentece Context
Table 1. Analysis of context sentence of quinacrine gene in 5 abstracts.
| pmid | sentence |
|---|---|
| 32619669 | In this context, this study aimed to evaluate in silico the molecular interactions of drugs with therapeutic indications for treatment of COVID-19 (Azithromycin, Baricitinib and Hydroxychloroquine) and drugs with similar structures (Chloroquine, Quinacrine and Ruxolitinib) in docking models from the SARS-CoV-2 main protease (M-pro) protein. […] Therefore, this study allows proposing the use of baricitinib and quinacrine, in combination with azithromycin; however, these computer simulations are just an initial step for conceiving new projects for the development of antiviral molecules. |
| 33116299 | Using hPSC-LOs, we performed a high-throughput screen of drugs approved by the FDA (US Food and Drug Administration) and identified entry inhibitors of SARS-CoV-2, including imatinib, mycophenolic acid and quinacrine dihydrochloride. |
| 33506949 | Quinacrine (Qx) has been used since the 1930s as preventive antimalarial compound. […] Herein, we review the potential mechanisms associated with quinacrine as an antiviral compound. |