DrugBank ID: db00794
Synonymous :2-deoxyphenobarbital | 5-phenyl-5-ethyl-hexahydropyrimidine-4,6-dione | primidon | primidona | primidone | primidonum
Drug Sentece Context
Table 1. Analysis of context sentence of primidone gene in 4 abstracts.
|33273695||Therefore, we searched for a RIPK1 inhibitor and present the aromatic antiepileptic and FDA-approved drug primidone (Liskantin®) as a potent inhibitor of RIPK1 activation in vitro and in a murine model of TNFα-induced shock, which mimics the hyperinflammatory state of cytokine release syndrome. […] Our data provide a strong rationale for evaluating the drug primidone in conditions of hyperinflammation in humans.|